Kyle J. Norton
Diabetes is a medical condition caused by not insufficient insulin entering the bloodstream.
In other words, diabetes is a condition associated with the inability of the body to use insulin properly.
Most cases of insulin insufficiency in the bloodstream in diabetes are either caused by the gradual died-off of the pancreas beta cells or insulin receptors clogged up by fat and cholesterol.
Hallmarks of diabetes are hyperglycemia and insulin resistance.
According to the statistics, in 2017, 7.3% of Canadians aged 12 and older (roughly 2.3 million people) reported being diagnosed with diabetes
The most common causes of diabetes are
* Metabolic syndrome
Metabolic syndrome is a cluster of conditions including high blood pressure, cholesterol, and glucose
associated with an increased risk of diabetes.
* Gestational diabetes
High blood glucose in pregnant women has been found to increase the risk of diabetes in later life.
* Prediabetes
Most cases of prediabetes are caused by unhealthy diets with high saturated fat, smoking, and excessive alcohol drinking. Prediabetes is a high-risk state for diabetes, especially in patients who remain with prediabetes despite intensive lifestyle intervention.
* Damage to the Pancreas causes the gradual and irreversible loss of beta cells that reduce the production of insulin
* Influenza a viruses
Influenza A virus is a common cause of pancreatitis in naturally and experimentally infected animals.
However, recently, researchers found that influenza virus infection may play a role as a causative agent of pancreatitis and diabetes in humans.
* * Head trauma
Head trauma is considered a possible cause of central diabetes insipidus with symptoms of failure to concentrate urine, and an increase in urine specific gravity.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that processes anti-diabetes properties, researchers investigated the effect of different fractions of Cucumis prophetarum on antidiabetic and antioxidant activity.
The study was carried out to examine the anti-diabetes and antioxidants of the different doses of aqueous crude extract (CE) of C. prophetarum fruits fractionated into water-soluble fraction 1 (F1), chloroform fraction 2 (F2), basic fraction 3 (F3), and neutral fraction 4 (F4) by acid-base extraction,
Based on the chemical analysis,
* F1 exhibited effective antidiabetic activity with an IC50 value of 20.6 and 59.9 µg/mL.
* According to the α-amylase assay, the anti-diabetes activity was found in the decreasing order of CE > F4 > F3 > F2.
* According to the DPPH assay, F1 (IC50 = 73 µg/mL) showed better-reducing ability than CE >F4 >F2 > F3 (IC50 = 78-272 µg/mL
* Furthermore, according to the SO and metal chelation assays, F1 showed the highest activity anti-diabetes at the IC50 = 101 and 147 µg/mL.
These results strongly suggested that F1 possesses a potent antidiabetic compared to other fractions, in vitro.
In other words, all ingredients in cucumbers work synergistically to exhibit anti-diabetes activity compared to a single compound.
Taken together, cucumber may be used for the treatment of diabetes, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antidiabetic and antioxidant potency evaluation of different fractions obtained from Cucumis prophetarum fruit by Gawli K1, Lakshmidevi N. (PubMed)
(2) Cucurbitacin B Induces Hypoglycemic Effect in Diabetic Mice by Regulation of AMP-Activated Protein Kinase Alpha and Glucagon-Like Peptide-1 via Bitter Taste Receptor Signaling by Kim KH1,2, Lee IS1,2, Park JY1,2, Kim Y1,2, An EJ1,2, Jang HJ. (PubMed)
(3) Diabetes – The Causes by Kyle J. Norton
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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Tuesday, 1 August 2023
#Potatoes Process a Strong Anti-Inflammatory Activity, According to Studies
Kyle J. Norton
Inflammation is a natural defense of the immune system that protects the body against the insult from foreign invasion.
Acute inflammation occurs quickly or within hours and lasts a few days or weeks and the damaged tissues are healed themselves after all pathogens are killed off.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
However, overexpression of inflammatory cytokines in most cases can cause improper healing with scar formation or the death of nearby cells.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
However, if the immune system can not completely eradicate all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.
Chronic inflammation also can be caused by overexpression of free radicals compared to the antioxidant enzymes in the body. This result can lead to an imbalance of the ratio of the levels of free radicals and antioxidants, the major cause of oxidative stress.
Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.
However, in people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
Longer-term oxidative stress in the body can also cause oxidative damage to biomolecules, including lipids, proteins, and DNA damage.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.
Potato is the genus Solanum and belongs to the family Solanaceae. The veggie is a good source of protein and according to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. It now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
In finding a potential plant that processes anti-inflammatory activity researchers examined the pharmacological potential of dehydrated potatoes on inflammation.
In the bioaccessible peptides that were fractionated on tested intestinal epithelial cells (IEC-6) under oxidative and inflammatory conditions,
* The tested peptide fractions demonstrated a significant inhibition in the production of pro-inflammatory cytokines, tumor necrosis factor-α release, and cycloxygenase-2 and inducible nitric oxide synthase expression.
* The tested peptides also showed significant antioxidant activity against the inflammatory process by inhibiting the levels of reactive oxygen species (ROS) from mitochondria, and nitrotyrosine formation, and increasing the antioxidant response by heme oxygenase-1 and superoxide dismutase expression.
* Moreover, the peptide fractions showed a significant increase in wound repair in IEC-6 activity through its anti-inflammatory property.
Collectively, researchers said, "The obtained results indicate the anti-inflammatory potential of dehydrated potatoes at the intestinal level".
Taken together, potatoes may be considered a functional food for the prevention and treatment of inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells by Basilicata MG1,2, Pepe G1, Rapa SF1, Merciai F1,2, Ostacolo C3, Manfra M4, Di Sarno V1, Autore G1, De Vita D5, Marzocco S1, Campiglia P. (PubMed)
Inflammation is a natural defense of the immune system that protects the body against the insult from foreign invasion.
Acute inflammation occurs quickly or within hours and lasts a few days or weeks and the damaged tissues are healed themselves after all pathogens are killed off.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
However, overexpression of inflammatory cytokines in most cases can cause improper healing with scar formation or the death of nearby cells.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
However, if the immune system can not completely eradicate all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.
Chronic inflammation also can be caused by overexpression of free radicals compared to the antioxidant enzymes in the body. This result can lead to an imbalance of the ratio of the levels of free radicals and antioxidants, the major cause of oxidative stress.
Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.
However, in people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
Longer-term oxidative stress in the body can also cause oxidative damage to biomolecules, including lipids, proteins, and DNA damage.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.
Potato is the genus Solanum and belongs to the family Solanaceae. The veggie is a good source of protein and according to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. It now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
In finding a potential plant that processes anti-inflammatory activity researchers examined the pharmacological potential of dehydrated potatoes on inflammation.
In the bioaccessible peptides that were fractionated on tested intestinal epithelial cells (IEC-6) under oxidative and inflammatory conditions,
* The tested peptide fractions demonstrated a significant inhibition in the production of pro-inflammatory cytokines, tumor necrosis factor-α release, and cycloxygenase-2 and inducible nitric oxide synthase expression.
* The tested peptides also showed significant antioxidant activity against the inflammatory process by inhibiting the levels of reactive oxygen species (ROS) from mitochondria, and nitrotyrosine formation, and increasing the antioxidant response by heme oxygenase-1 and superoxide dismutase expression.
* Moreover, the peptide fractions showed a significant increase in wound repair in IEC-6 activity through its anti-inflammatory property.
Collectively, researchers said, "The obtained results indicate the anti-inflammatory potential of dehydrated potatoes at the intestinal level".
Taken together, potatoes may be considered a functional food for the prevention and treatment of inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells by Basilicata MG1,2, Pepe G1, Rapa SF1, Merciai F1,2, Ostacolo C3, Manfra M4, Di Sarno V1, Autore G1, De Vita D5, Marzocco S1, Campiglia P. (PubMed)
#Broccoli's BCE-I Mainly Consisted of Galactose and Arabinose Exhibits Anti-Metastatic Activities by Exhibiting the Natural Killer (NK) Cells, Researchers Show
Kyle J. Norton
Cancer is a class of diseases associated with irregular cell growth in the tissue of a specific organ.
Most cases of invasive cancer can spread to other organs in the body via lymph or blood.
According to the statistics provided by the Cancer Institute, between n 2011–2015, the number of new cases of cancer is 439.2 per 100,000 men and women per year (based on 2011–2015 cases).
The number of cancer deaths (cancer mortality) is 163.5 per 100,000 men and women per year.
In cancer cells, due to the alternation of DNA, can grow indefinitely.
Cancer cell metastasis is the process in that cancer cells break away from the primary site and travel through the blood or fluid circulation and form new tumors (metastatic tumors) in other parts of the body, similar to those of primary cancer.
The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases.
Through the expression of the lines of defense, depending on the stage of pathogenic invasion, the innate immune response protects the body via a different set of interactions.
In the acute phase of infection, the macrophages in the immune system stimulate the production of inflammatory cytokines at the site of the damage. The inflammatory cytokines not only play a critical role in stopping the stimuli from entering the body but also speeds up wound healing through growth factors.
The innate immune system also can destroy damaged cells such as cancer cells through the T cell activation of B cells which in turn stimulates the production of a protein associated with the production of antibody p53.
Some researchers suggested immune system also can kill cancer cells by reacting to activating cytokines (IFN-α/β, IL-12, IL-15, IL-18, IL-21) produced by tumor cells or by other immune cells stimulated by tumor cells.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
In finding natural food for the prevention and treatment of cancer proliferation, researchers examined the anti-metastatic activities of polysaccharides in broccoli, including BCE-I mainly consisted of galactose and arabinose, whereas BCE-II mainly consisted of galacturonic acid and rhamnose, and BCE-III mainly consisted of rhamnose and galactose.
According to the results of the analysis,
* BCE-I showed the greatest enhancement of the pro-inflammatory proteins such as tumor necrosis factor-α, interleukin (IL)-12, and IL-6 secretion by stimulating murine peritoneal macrophages in the immune response.
* Furthermore, intravenous (i.v.) administration of BCE-I enhanced the lethal activity on YAC-1 tumor cells significantly and dose-dependently in an ex vivo by exhibiting the natural killer (NK) cells.
* In lung metastasis of Colon26-M3.1 carcinoma cells, prophylactic i.v. and oral administration of BCE-I significantly and dose-dependently inhibited lung metastatic activity.
In other words, the inhibitory activity of BCE-1 on lung metastasis are depending on the NK cell function in GM1 activity.
Based on the results, researchers wrote, " BCE-I has potent antitumor metastatic activity, and that its anti-metastatic activity has relevance to the stimulation of NK and other immune cells".
Taken together, broccoli sprouts processed abundantly SFN may be considered supplements for inhibiting cancer cell metastasis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation by Kwak BS1, Hwang D2,3, Lee SJ1, Choi HJ4, Park HY5, Shin KS. (PubMed)
#Lycopene Extract Combined with Serenoa Repens, Selenium, + Bromelain and Methylsulfonylmethane Extract Inhibit the Onset of Chronic Bacterial Prostatitis, According to Studies
Kyle J. Norton
Prostatitis is a condition associated with the inflammation of the prostate and the areas around the prostate.
Chronic bacterial prostatitis is a medical condition of prostatitis induced by a bacterial infection.
According to the statistics provided by the American Family Physician, approximately 8.2 percent of men in the US are living with prostatitis. The conditions account for 8 percent of visits to urologists, and up to 1 percent of visits to primary care physicians.
Believe it or not, in 2000, prostatitis has cost over $84 million, including the charge of diagnosis and treatment.
The most common symptoms of prostatitis are painful, difficult and/or frequent urinating, groin pain, rectal pain, abdominal pain and/or low back pain, fever, chills, and body aches.
In severe cases, patients may also experience symptoms of urethral discharge, painful ejaculation or sexual dysfunction, and blood in the urine.
The exact causes of prostatitis are not identified, some researchers suggested that nerve damage in the lower urinary tract caused by surgery or trauma to the area has been found to induce prostatitis in patients.
Conventionally, most cases of prostatitis are treated by antibiotics in cases of infection, alpha-blockers to relax the bladder neck, and muscle fibers, and anti-inflammatory medicine to ease pain and discomforts.
Dr. JAMES J. STEVERMER, the lead scientist in the treatment of chronic bacterial prostatitis at the University of Missouri–Columbia School of Medicine, wrote, "If the patient responds to therapy, antibiotics are continued for at least three to four weeks, although some men require treatment for several months. A patient who does not respond might be evaluated for chronic nonbacterial prostatitis, in which nonsteroidal anti-inflammatory drugs, alpha-blocking agents, anticholinergic agents, or other therapies may provide symptomatic relief".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of prostatitis, researchers evaluated the efficacy and the safety of a combination of Serenoa repens, selenium, and lycopene extract + bromelain and methylsulfonylmethane extract associated with levofloxacin in patients with chronic bacterial prostatitis (CBP).
The study included all patients with a clinical and instrumental diagnosis of CBP, admitted to a single Urological Institution from March to June 2015 were enrolled in this phase III study.
All selected patients were randomized into two groups, Group A (n=40)received levofloxacin 500 mg o.d. for 14 days associated with lycopene and methylsulfonylmethane; Group B (n=39) received levofloxacin (500 mg o.d. for 14 days) only.
According to the results from the follow-up (T1), the NIH Chronic Prostatitis Symptom Index (CPSI), and International Prostatic Symptom Score (IPSS) of group A were significantly lower compared to group B.
In other words, group A showed milder symptoms compared to group B.
Furthermore, the symptomatic and microbiological recurrence was also significantly lower in group A n=1) compared to group B (n=7).
Moreover, these change between groups was continued at the second follow-up visit (T2) observed by the questionnaire results.
Based on the findings, researchers said, "The combination of Serenoa repens, selenium, lycopene + bromelain, and methylsulfonylmethane extracts improved the clinical efficacy of levofloxacin in patients affected by CBP without the development of side effects".
Taken together, lycopene found in tomatoes may be considered an adjunct therapy for the treatment of chronic bacterial prostatitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients by Cai T1, Tiscione D, Gallelli L, Verze P, Palmieri A, Mirone V, Bartoletti R, Malossini G. (PubMed)
(2) Treatment of Prostatitis by JAMES J. STEVERMER, M.D., M.S.P.H., and SUSAN K. EASLEY, M.D. (the University of Missouri–Columbia School of Medicine, Columbia, Missouri)
Prostatitis is a condition associated with the inflammation of the prostate and the areas around the prostate.
Chronic bacterial prostatitis is a medical condition of prostatitis induced by a bacterial infection.
According to the statistics provided by the American Family Physician, approximately 8.2 percent of men in the US are living with prostatitis. The conditions account for 8 percent of visits to urologists, and up to 1 percent of visits to primary care physicians.
Believe it or not, in 2000, prostatitis has cost over $84 million, including the charge of diagnosis and treatment.
The most common symptoms of prostatitis are painful, difficult and/or frequent urinating, groin pain, rectal pain, abdominal pain and/or low back pain, fever, chills, and body aches.
In severe cases, patients may also experience symptoms of urethral discharge, painful ejaculation or sexual dysfunction, and blood in the urine.
The exact causes of prostatitis are not identified, some researchers suggested that nerve damage in the lower urinary tract caused by surgery or trauma to the area has been found to induce prostatitis in patients.
Conventionally, most cases of prostatitis are treated by antibiotics in cases of infection, alpha-blockers to relax the bladder neck, and muscle fibers, and anti-inflammatory medicine to ease pain and discomforts.
Dr. JAMES J. STEVERMER, the lead scientist in the treatment of chronic bacterial prostatitis at the University of Missouri–Columbia School of Medicine, wrote, "If the patient responds to therapy, antibiotics are continued for at least three to four weeks, although some men require treatment for several months. A patient who does not respond might be evaluated for chronic nonbacterial prostatitis, in which nonsteroidal anti-inflammatory drugs, alpha-blocking agents, anticholinergic agents, or other therapies may provide symptomatic relief".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of prostatitis, researchers evaluated the efficacy and the safety of a combination of Serenoa repens, selenium, and lycopene extract + bromelain and methylsulfonylmethane extract associated with levofloxacin in patients with chronic bacterial prostatitis (CBP).
The study included all patients with a clinical and instrumental diagnosis of CBP, admitted to a single Urological Institution from March to June 2015 were enrolled in this phase III study.
All selected patients were randomized into two groups, Group A (n=40)received levofloxacin 500 mg o.d. for 14 days associated with lycopene and methylsulfonylmethane; Group B (n=39) received levofloxacin (500 mg o.d. for 14 days) only.
According to the results from the follow-up (T1), the NIH Chronic Prostatitis Symptom Index (CPSI), and International Prostatic Symptom Score (IPSS) of group A were significantly lower compared to group B.
In other words, group A showed milder symptoms compared to group B.
Furthermore, the symptomatic and microbiological recurrence was also significantly lower in group A n=1) compared to group B (n=7).
Moreover, these change between groups was continued at the second follow-up visit (T2) observed by the questionnaire results.
Based on the findings, researchers said, "The combination of Serenoa repens, selenium, lycopene + bromelain, and methylsulfonylmethane extracts improved the clinical efficacy of levofloxacin in patients affected by CBP without the development of side effects".
Taken together, lycopene found in tomatoes may be considered an adjunct therapy for the treatment of chronic bacterial prostatitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients by Cai T1, Tiscione D, Gallelli L, Verze P, Palmieri A, Mirone V, Bartoletti R, Malossini G. (PubMed)
(2) Treatment of Prostatitis by JAMES J. STEVERMER, M.D., M.S.P.H., and SUSAN K. EASLEY, M.D. (the University of Missouri–Columbia School of Medicine, Columbia, Missouri)
#Strawberries Exert Neuro-Protective Activity by Inhibiting the Expression of Free Radicals, According to Studies
Kyle J. Norton
StrawberriesStrawberries are a genius of Fragaria × ananassa and belong to the family Rosaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.
Neuroprotective effects are defined as an event that protects the central nervous system (CNS) by relatively preserving neuronal structure and/or function.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
Many studies have been carried out by scientists to explore the effective agent which has the potential to prevent or slow disease progression and secondary injuries by halting or at least slowing the loss of neurons.
StrawberriesStrawberries are a genius of Fragaria × ananassa and belong to the family Rosaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.
Neuroprotective effects are defined as an event that protects the central nervous system (CNS) by relatively preserving neuronal structure and/or function.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
Many studies have been carried out by scientists to explore the effective agent which has the potential to prevent or slow disease progression and secondary injuries by halting or at least slowing the loss of neurons.
In spite of mitochondrial oxidative stress (MOS) as a major factor in the underlying pathology of many neurodegenerative diseases, chemical constituent anthocyanins suppress MOS-induced apoptosis by preserving mitochondrial GSH and inhibiting cardiolipin oxidation and mitochondrial fragmentation.
Also in the study of Berry fruit supplementation, polyphenolic compounds found in berry fruits, such as blueberries and strawberries, may exert their beneficial effects either through their ability to lower oxidative stress and inflammation or directly by altering the signaling involved in neuronal communication, calcium buffering ability, neuroprotective stress shock proteins, plasticity, PubMed and stress signaling pathways.
Dr. Richardson JS. indicated that pharmacological agents that protect damaged neurons are not ready yet for widespread clinical use, neuron damaging oxidative stress can be kept in check by ensuring adequate dietary sources of antioxidants with little or no scientific evidence, but the consumption of high-antioxidant foods, such as blueberries and strawberries, is appealing to most people regardless of any neuroprotective potential.
Reference
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) The Promise of Neuroprotective Agents in Parkinson’s Disease by Stacey E. Seidl and Judith A. Potashkin(Frontiers in Neurology)
(4) Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. by Kelsey N, Hulick W, Winter A, Ross E, Linseman D.(PubMed)
(5) Neuroprotective agents. by Richardson JS.(PubMed)
(6) Berry fruit supplementation and the aging brain. by Shukitt-Hale B, Lau FC, Joseph JA.(PubMed)
Reference
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) The Promise of Neuroprotective Agents in Parkinson’s Disease by Stacey E. Seidl and Judith A. Potashkin(Frontiers in Neurology)
(4) Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. by Kelsey N, Hulick W, Winter A, Ross E, Linseman D.(PubMed)
(5) Neuroprotective agents. by Richardson JS.(PubMed)
(6) Berry fruit supplementation and the aging brain. by Shukitt-Hale B, Lau FC, Joseph JA.(PubMed)
#Onion Peel #HydroalcoholicExtract (OPE) Exerts Vasorelaxant Effects Against the Risk of CardiovascularDisease, Researchers Show
Kyle J. Norton
Vasorelaxant is a term that refers to the reduction of vascular tension.
Vascular disease is a disease associated with an abnormal condition of the blood vessels, affecting the blood flow to the body.
There are many types of vascular disease associated with vascular constriction, including stroke, peripheral artery disease (PAD), a disease caused by reduced blood flow to the limbs, abdominal aortic aneurysm (AAA), carotid artery disease (CAD), arteriovenous malformation (AVM), pulmonary embolism (blood clots) and deep vein thrombosis (DVT).
According to the statistics, approximately 8.5 million people in the US are living with Peripheral artery disease (PAD), one of the most common types of vascular disease.
There are no single causes of vascular disease. However, diabetes, hyperlipidemia (high levels of fats in the blood, such as cholesterol and triglycerides), smoking, high blood pressure, obesity, and physical inactivity are some of the most prevalent factors found in patients with the condition.
Some researchers suggested that the rise of aging patients with vascular disease may be correlated to the promotion of a high-fat diet over the past few decades in inducing a large population with obesity and Type II diabetes in the US.
Dr. Morteza Mowlaie, the lead scientist wrote, " Significant positive association between left ventricular hypertrophy and plaque score and also a significant positive association between left ventricular hypertrophy with the presence of chest pain was found (p<0.05)"
And, "Association of diabetes mellitus with the presence of chest pain was positive. A positive correlation between hypertension with plaque score was demonstrated too (p<0.05). Also, an inverse association of plaque score with left ventricular ejection fraction was detected too (p<0.05)".
In other words, patients with diabetes are associated with vascular disease, that induces similar symptoms of atherosclerosis such as left ventricular hypertrophy, chest pain, and hypertension in plaque score
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
In finding a potent ingredient that processes cardioprotection researchers examined the investigate the effect of onion (Allium cepa) peel hydroalcoholic extract (OPE) on rat hypertension induced by a high-fructose diet and aorta contractility.
Three groups of rats were given fructose (10% WN/V) in drinking water for 6 weeks but the control group received tap water and the hypertensive groups received saline or OPE at 200, 400, and 800 mg kg(-1) daily for the last 3 weeks by gavage.
OPE reduces aorta contractions induced by KCl or Phe in a concentration-dependent manner through its vasorelaxant effects.
L-NAME (100 microM), methylene blue (10 microM), and indomethacin (10 microM) Inhibited nitric oxide, cGMP, and prostaglandin synthesis associated with a decrease of vasodilation also inhibited by the administration of OPE.
Furthermore, OPE did not change heart rate but reduced hypertension induced by fructose after 3 weeks of the experimental period.
The efficacy of OPE vasorelaxant activity was attributed to the inhibition of hypertension by extracting quercetin content, antioxidant activity, and inhibiting vascular smooth muscle cell's Ca2+ influx associated with the change of vascular diameter.
Taken together, onion may be considered a remedy for the promotion of vasorelaxant activity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Vasorelaxant and hypotensive effects of Allium cepa peel hydroalcoholic extract in rat by Naseri MK1, Arabian M, Badavi M, Ahangarpour A. (PubMed)
(2) Close association of arterial plaques with left ventricular hypertrophy and ejection fraction in hemodialysis patients by Morteza Mowlaie 1 and Hamid Nasri. (PMC)
Vasorelaxant is a term that refers to the reduction of vascular tension.
Vascular disease is a disease associated with an abnormal condition of the blood vessels, affecting the blood flow to the body.
There are many types of vascular disease associated with vascular constriction, including stroke, peripheral artery disease (PAD), a disease caused by reduced blood flow to the limbs, abdominal aortic aneurysm (AAA), carotid artery disease (CAD), arteriovenous malformation (AVM), pulmonary embolism (blood clots) and deep vein thrombosis (DVT).
According to the statistics, approximately 8.5 million people in the US are living with Peripheral artery disease (PAD), one of the most common types of vascular disease.
There are no single causes of vascular disease. However, diabetes, hyperlipidemia (high levels of fats in the blood, such as cholesterol and triglycerides), smoking, high blood pressure, obesity, and physical inactivity are some of the most prevalent factors found in patients with the condition.
Some researchers suggested that the rise of aging patients with vascular disease may be correlated to the promotion of a high-fat diet over the past few decades in inducing a large population with obesity and Type II diabetes in the US.
Dr. Morteza Mowlaie, the lead scientist wrote, " Significant positive association between left ventricular hypertrophy and plaque score and also a significant positive association between left ventricular hypertrophy with the presence of chest pain was found (p<0.05)"
And, "Association of diabetes mellitus with the presence of chest pain was positive. A positive correlation between hypertension with plaque score was demonstrated too (p<0.05). Also, an inverse association of plaque score with left ventricular ejection fraction was detected too (p<0.05)".
In other words, patients with diabetes are associated with vascular disease, that induces similar symptoms of atherosclerosis such as left ventricular hypertrophy, chest pain, and hypertension in plaque score
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
In finding a potent ingredient that processes cardioprotection researchers examined the investigate the effect of onion (Allium cepa) peel hydroalcoholic extract (OPE) on rat hypertension induced by a high-fructose diet and aorta contractility.
Three groups of rats were given fructose (10% WN/V) in drinking water for 6 weeks but the control group received tap water and the hypertensive groups received saline or OPE at 200, 400, and 800 mg kg(-1) daily for the last 3 weeks by gavage.
OPE reduces aorta contractions induced by KCl or Phe in a concentration-dependent manner through its vasorelaxant effects.
L-NAME (100 microM), methylene blue (10 microM), and indomethacin (10 microM) Inhibited nitric oxide, cGMP, and prostaglandin synthesis associated with a decrease of vasodilation also inhibited by the administration of OPE.
Furthermore, OPE did not change heart rate but reduced hypertension induced by fructose after 3 weeks of the experimental period.
The efficacy of OPE vasorelaxant activity was attributed to the inhibition of hypertension by extracting quercetin content, antioxidant activity, and inhibiting vascular smooth muscle cell's Ca2+ influx associated with the change of vascular diameter.
Taken together, onion may be considered a remedy for the promotion of vasorelaxant activity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Vasorelaxant and hypotensive effects of Allium cepa peel hydroalcoholic extract in rat by Naseri MK1, Arabian M, Badavi M, Ahangarpour A. (PubMed)
(2) Close association of arterial plaques with left ventricular hypertrophy and ejection fraction in hemodialysis patients by Morteza Mowlaie 1 and Hamid Nasri. (PMC)
#Potatoes Inhibit Markers Associated with the Liver Injury and Damage, Researchers Say
Kyle J. Norton
Fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the organ tissues In other words, hepatic fibrosis is a portion of the liver that was affected by scar formation.
The exact causes of fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of fibrosis.
The 2 most common types of fibrosis in the human body are
* Renal fibrosis is a progressive condition caused by excessive accumulation of extracellular matrix including collagen, enzymes, and glycoproteins which provided structural and biochemical support of surrounding the renal cells during aging and chronic kidney disease (CKD).
According to the statistics, CKD and renal fibrosis affect approximately half of the adults age 70 and over and 10% of the world's population.
In other words, renal fibrosis is a direct consequence caused by the inability of the kidney to regenerate after injury, leading to the formation of renal scars that results in a progressive loss of renal function.
Most cases of renal fibrosis ultimately lead to end-stage renal failure and a need for dialysis or kidney transplantation.
* Liver fibrosis is a chronic liver disease due to liver scars overwhelmingly building up in the connective tissue in the liver.
A severe case of hepatic fibrosis can lead to cirrhosis, affecting the liver function in filtering the blood. In the US, over 4.5 million people are affected by liver cirrhosis, leading to the death of 12/100,000 of the population every year.
The most common causes of liver fibrosis are excessive alcohol drinking and infection with the hepatitis virus.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of severe scarring of the liver and life-threatening liver disease.
Potato is the genus Solanum, and belongs to the family Solanaceae. the root veggie is a good source of protein.
According to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. Potato now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
In finding a potential plant that processes anti-fibrotic activity researchers examined the effect of APPH, a potato protein hydrolysate on a high-fat diet (HFD) associated liver damage.
The study included six-week-old male hamsters that were randomly separated into six groups (n = 8) as control, HFD (HFD fed obese), L-APPH (HFD + 15 mg/kg/day of APPH), M-APPH (HFD + 30 mg/kg/day), H-APPH (HFD + 75 mg/kg/day of APPH) and PB (HFD + 500 mg/kg/day of probucol) with HFD fed hamsters were administered with APPH 50 days through oral gavage.
According to the results of the analysis,* Hamsters fed with a high-fat diet showed symptoms of liver damage as measured from serum stress markers like alanine aminotransferase and aspartate aminotransferase levels.
* Furthermore, HFD also modulated the expression of survival and apoptosis proteins in the hamster liver.
* Moreover, the HFD groups showed elevated levels of fibrosis markers in the liver correlated with the increase in the levels of phosphorylated extracellular signal-regulated kinases (pERK1/2) induced liver cell differentiation in the HFD-mediated liver damage.
* The administration of a 50-day long supplementation of APPH effectively ameliorated the effects of HFD.
* APPH treatment reduced the effect of HFD on the apoptosis and fibrosis markers considerably and provided hepato-protection.
Collectively, researchers said, "APPH can, therefore, be considered as an efficient therapeutic agent to ameliorate high-fat diet-related liver damages".
Taken altogether, potato may be considered a functional food for the prevention and treatment of liver fibrosis and damage induced fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protein hydrolysate from potato confers hepatic-protection in hamsters against high-fat diet-induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway by Asokan SM1,2, Hung TH3, Li ZY3, Chiang WD4, Lin WT. (PubMed)
Fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the organ tissues In other words, hepatic fibrosis is a portion of the liver that was affected by scar formation.
The exact causes of fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of fibrosis.
The 2 most common types of fibrosis in the human body are
* Renal fibrosis is a progressive condition caused by excessive accumulation of extracellular matrix including collagen, enzymes, and glycoproteins which provided structural and biochemical support of surrounding the renal cells during aging and chronic kidney disease (CKD).
According to the statistics, CKD and renal fibrosis affect approximately half of the adults age 70 and over and 10% of the world's population.
In other words, renal fibrosis is a direct consequence caused by the inability of the kidney to regenerate after injury, leading to the formation of renal scars that results in a progressive loss of renal function.
Most cases of renal fibrosis ultimately lead to end-stage renal failure and a need for dialysis or kidney transplantation.
* Liver fibrosis is a chronic liver disease due to liver scars overwhelmingly building up in the connective tissue in the liver.
A severe case of hepatic fibrosis can lead to cirrhosis, affecting the liver function in filtering the blood. In the US, over 4.5 million people are affected by liver cirrhosis, leading to the death of 12/100,000 of the population every year.
The most common causes of liver fibrosis are excessive alcohol drinking and infection with the hepatitis virus.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of severe scarring of the liver and life-threatening liver disease.
Potato is the genus Solanum, and belongs to the family Solanaceae. the root veggie is a good source of protein.
According to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. Potato now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.
In finding a potential plant that processes anti-fibrotic activity researchers examined the effect of APPH, a potato protein hydrolysate on a high-fat diet (HFD) associated liver damage.
The study included six-week-old male hamsters that were randomly separated into six groups (n = 8) as control, HFD (HFD fed obese), L-APPH (HFD + 15 mg/kg/day of APPH), M-APPH (HFD + 30 mg/kg/day), H-APPH (HFD + 75 mg/kg/day of APPH) and PB (HFD + 500 mg/kg/day of probucol) with HFD fed hamsters were administered with APPH 50 days through oral gavage.
According to the results of the analysis,* Hamsters fed with a high-fat diet showed symptoms of liver damage as measured from serum stress markers like alanine aminotransferase and aspartate aminotransferase levels.
* Furthermore, HFD also modulated the expression of survival and apoptosis proteins in the hamster liver.
* Moreover, the HFD groups showed elevated levels of fibrosis markers in the liver correlated with the increase in the levels of phosphorylated extracellular signal-regulated kinases (pERK1/2) induced liver cell differentiation in the HFD-mediated liver damage.
* The administration of a 50-day long supplementation of APPH effectively ameliorated the effects of HFD.
* APPH treatment reduced the effect of HFD on the apoptosis and fibrosis markers considerably and provided hepato-protection.
Collectively, researchers said, "APPH can, therefore, be considered as an efficient therapeutic agent to ameliorate high-fat diet-related liver damages".
Taken altogether, potato may be considered a functional food for the prevention and treatment of liver fibrosis and damage induced fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protein hydrolysate from potato confers hepatic-protection in hamsters against high-fat diet-induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway by Asokan SM1,2, Hung TH3, Li ZY3, Chiang WD4, Lin WT. (PubMed)
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