Kyle J. Norton
Aging is the natural and biological process of growing older.
You can not stop the aging clock, but, you can delay the progression by taking some preventive actions, including living a healthy lifestyle accompanied by moderate exercise.
Healthy aging refers to the creation of a series of conditions that allow the aging population to live functionally without being affected by serious chronic diseases or medical conditions (that are well-managed).
The World Health Organization in the definition of healthy aging wrote, "healthy aging as the process of developing and maintaining the functional ability that enables wellbeing in older age” and "Functional ability is about having the capabilities that enable all people to be and do what they have reason to value".
In other words, healthy aging must comprise all the mental and physical capacities such as the ability to walk, think, see, hear, and remember, particularly in bathing, dressing, and other independent living skills, such as shopping and housework.
Dr. Ruth Elaine Nieuwenhuis-Mark in the study of healthy aging as a disease wrote, "A popular theory in the aging literature since the early 1990s is the socioemotional selectivity theory (SST; Carstensen, 1992). SST was put forward as an attempt to explain the so-called “paradox of aging” which refers to the finding that while physical health tends to decline as we age subjective well-being may be maintained or even improve (Diener and Suh, 1998)".
And, "Focusing on normal aging as a disease could, therefore, be seen as a step-back for aging research rather than a move forward. Aging-as-disease proponents would argue however that their focus is on improving quality of life in our final years, not on increasing our lifespans per se".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers in aim to a natural compound that processes antiaging property examined the effects of bilberry anthocyanin extract consumption in healthy aging and intestinal barrier function and digestive enzyme activity, through regulating the gut microbiota in aging rats.
The study included aging rats fed with the medium-dose bilberry anthocyanin extract (20 mg per kg bw per day) in the regulation of intestinal function.
Consumption of the extract showed strong activity in the gut by allowing the bacteria beneficial in the intestine (Aspergillus oryzae, Lactobacillus, Bacteroides, Clostridiaceae-1, the Bacteroidales-S24-7-group, and the Lachnospiraceae_NK4A136_group) to grow, and inhibiting the growth of harmful bacteria (Verrucomicrobia and Euryarchaeota).
However, high-dose bilberry anthocyanin extract consumption was found to induce a negative effect in alternating some intestinally beneficial bacteria.
Furthermore, bilberry anthocyanin extract consumption also decreased the activity of digestive enzymes in breaking down food correlated to the changes in bacterial composition, short-chain fatty acids, and the intestinal mucosal barrier.
In other words, bilberry anthocyanin extract consumption improved digestive function without affecting the activity of the digestive enzyme which has been found in low levels in people with the digestive problem including the aging population.
Dr. Li J, the lead scientist said, "Bilberry anthocyanin extract consumption is a potential approach for assisting healthy aging".
The finding suggested that bilberry anthocyanin extract has a significant anti-aging effect by optimizing the function of the digestive system through wide range of mechanisms, including bacterial composition.
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered an anti-aging remedy, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Bilberry anthocyanin extract promotes intestinal barrier function and inhibits digestive enzyme activity by regulating the gut microbiota in aging rats by Li J1, Wu T1, Li N1, Wang X1, Chen G1, Lyu X1. (PubMed)
(2) The senescence-accelerated mouse-prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals by Schiborr C1, Schwamm D, Kocher A, Rimbach G, Eckert GP, Frank J. (PubMed)
(3) Healthy Aging as Disease? by Ruth Elaine Nieuwenhuis-Mark. (PubMed)
(4) What is Healthy Ageing? (WHO)
Monday, 24 July 2023
#Bromelain Is Effective for the Treatment of Flu Influenza Depeding on the Types of Bromeline, Reserachers Say
Kyle J. Norton
Influenza A, B, C, and D are 4 types of flu influenza. Influenza viruses A and B are seasonal flu occurred during the fall, winter, and early spring, which cause sniffling, aching, coughing, running and stuffy nose, and fever, affecting over 20% of the general population.
Influenza virus types C in the virus family Orthomyxoviridae tends to cause mild upper respiratory infections, similar to those of cold.
Influenza D viruses only affect cattle.
Individuals who have influenza are usually recovered within one week and symptoms are gone within 2 weeks.
However, people with the immature and weakened immune system including young children under age 5, adults older than age 65, elderly in nursing homes and other long-term care facilities, and chronic illnesses, such as asthma, heart disease, kidney disease, liver disease, and diabetes are not only associated with the risk of influenza but also increase the risk of influenza deadly complications.
Pregnant women and women up to two weeks postpartum due to changes in the immune system are more prone to influenza and influenza complications.
The most common H and N subtypes are influenza A which has been mutated to affect the combination of human, swine, and bird flu viruses, including
* H1N1 - Swine Flu
H1N1 normally is only transmitted among pigs. However, as of today, H1N1 became the first flu pandemic in the world that causes respiratory illness.
* H5N1 - Bird Flu
H5N1 is the strain of influenza known as bird or avian flu. Before, it is transmitted between birds, but today, it now can be passed from bird to human. The strain is dangerous to humans with high death rates.
The most common symptoms of influenza are high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and persistent fatigue.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the prevention and treatment of influenza, researchers compared the effect of two preparations of bromeline ("Sigma Co., Catalogues' Nos. B2252 and B5144).s
According to the tested assay, in the influenza A(H1N1) virus, B5144 did not have any impact on it under similar experimental conditions.
Furthermore, B5144 also showed an incomplete effect on the influenza A(H3N2) virus with particles (with intact external coatings).
However, enzyme B2252 was effective for all viruses selected for testing, with the highest effect noted for influenza A(H1N1) and B viruses.
In other words, not all bromlines are the same, some are more effective in the inhibition of viral influenza than the others.
Taken together, preparations of bromeline generation from bromelain may be considered a remedy for the prevention and treatment of influenza, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage by Wang W1, Suguitan AL Jr, Zengel J, Chen Z, Jin H. (PubMed)
(2) [The use of bromelain in obtaining the subviral particles of influenza A and B viruses].[Article in Russian] by Ivanova VT, Kordiukova LV, Manykin AA, Burtseva EI, Zagorskaia IuV, Oskerko TA, Slepushkin AN. (PubMed)
Influenza A, B, C, and D are 4 types of flu influenza. Influenza viruses A and B are seasonal flu occurred during the fall, winter, and early spring, which cause sniffling, aching, coughing, running and stuffy nose, and fever, affecting over 20% of the general population.
Influenza virus types C in the virus family Orthomyxoviridae tends to cause mild upper respiratory infections, similar to those of cold.
Influenza D viruses only affect cattle.
Individuals who have influenza are usually recovered within one week and symptoms are gone within 2 weeks.
However, people with the immature and weakened immune system including young children under age 5, adults older than age 65, elderly in nursing homes and other long-term care facilities, and chronic illnesses, such as asthma, heart disease, kidney disease, liver disease, and diabetes are not only associated with the risk of influenza but also increase the risk of influenza deadly complications.
Pregnant women and women up to two weeks postpartum due to changes in the immune system are more prone to influenza and influenza complications.
The most common H and N subtypes are influenza A which has been mutated to affect the combination of human, swine, and bird flu viruses, including
* H1N1 - Swine Flu
H1N1 normally is only transmitted among pigs. However, as of today, H1N1 became the first flu pandemic in the world that causes respiratory illness.
* H5N1 - Bird Flu
H5N1 is the strain of influenza known as bird or avian flu. Before, it is transmitted between birds, but today, it now can be passed from bird to human. The strain is dangerous to humans with high death rates.
The most common symptoms of influenza are high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and persistent fatigue.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the prevention and treatment of influenza, researchers compared the effect of two preparations of bromeline ("Sigma Co., Catalogues' Nos. B2252 and B5144).s
According to the tested assay, in the influenza A(H1N1) virus, B5144 did not have any impact on it under similar experimental conditions.
Furthermore, B5144 also showed an incomplete effect on the influenza A(H3N2) virus with particles (with intact external coatings).
However, enzyme B2252 was effective for all viruses selected for testing, with the highest effect noted for influenza A(H1N1) and B viruses.
In other words, not all bromlines are the same, some are more effective in the inhibition of viral influenza than the others.
Taken together, preparations of bromeline generation from bromelain may be considered a remedy for the prevention and treatment of influenza, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage by Wang W1, Suguitan AL Jr, Zengel J, Chen Z, Jin H. (PubMed)
(2) [The use of bromelain in obtaining the subviral particles of influenza A and B viruses].[Article in Russian] by Ivanova VT, Kordiukova LV, Manykin AA, Burtseva EI, Zagorskaia IuV, Oskerko TA, Slepushkin AN. (PubMed)
#WildOnion #Extracts Inhibit #ChemoCardiotoxicity through Its Antioxidant Activity, Researchers Say
Kyle J. Norton
Cardiotoxicity is a medical condition that causes damage to the heart muscle, leading to reduced heart muscles function to pump blood, and heart failure.
Long term intake of certain medication and people who are under treatment of chemotherapy have been found in most cases cardiotoxicity.
However, people who are infected by human immunodeficiency virus (HIV) genetic preposition, a malignant disease associated with the amyloid deposited on the heart or other organs, high blood pressure, untreated hyperthyroidism, and vitamin b2 deficiency are some of the most prevalent factors found in patients with cardiotoxicity.
Most common symptoms of cardiotoxicity are associated with not enough blood circulation in the body such as tiredness and fatigue, a long-term (chronic) cough, shortness of breath, floating due to the enlarged heart muscle, abnormal heart or lung sounds and swelling in your hands, feet, or unusual weight gain.
Conventionally, treatment of cardiotoxicity is totally depending on the types of the disease including
Beta-blockers, ACE inhibitors induce (widen) arterial dilation and improvement of the blood flow and diuretics.
Some researchers in examining the risk of cardiotoxicity in patients with chemotherapy wrote, "Age and preexisting left ventricular dysfunction have been identified most consistently as being associated with the development of clinical heart failure or a worsening of left ventricular function with chemotherapy".
And, ""Other cardiovascular conditions, including hypertension, diabetes, and coronary artery disease, are also associated with the risk of cardiotoxicity".
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In finding a potent ingredient that processes cardio-protective activity researchers examined the effects of extracts from edible wild onion species, Allium flavum, and Allium carinatum, which reduce side effects of cytostatic doxorubicin (Dox).
In human hepatoma (HepG2) and lung carcinoma (A549) cells, the methanol extracts exhibited high levels of antioxidant activity and worked synergistically to increased Dox anticancer activity, without affecting the health of normal cells.
Furthermore, antioxidative enzyme levels such as catalase and superoxide dismutases in the cancer cells were also suppressed by the chemicals, compared to normal cells upon applied treatments.
In the toxicity assays on the zebrafish model, the chemical extracts isolated from edible wild onion species process lower toxicity compared to Dox, with no teratogenic effects at applied doses.
Most importantly, the extracts not only successfully protect the Dox-treated embryos from life-threatening cardiomyopathy but also reduced developmental toxicity and neutropenia. in the zebrafish model.
Additionally, the extracts also processed a higher anti-angiogenic activity compared to those of antiangiogenic drugs such as sunitinib or auranofin.
Taken together, onion extracts may be considered a remedy for the prevention and treatment of cardio-toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Wild edible onions - Allium flavum and Allium carinatum - successfully prevent adverse effects of chemotherapeutic drug doxorubicin by Aleksandar P1, Dragana MĆ2, Nebojša J3, Biljana N3, Nataša S4, Branka V5, Jelena KV. (PubMed)
(2) Risk factors for chemotherapy-related cardiac toxicity by Polonsky TS1, DeCara JM. (PubMed)
Cardiotoxicity is a medical condition that causes damage to the heart muscle, leading to reduced heart muscles function to pump blood, and heart failure.
Long term intake of certain medication and people who are under treatment of chemotherapy have been found in most cases cardiotoxicity.
However, people who are infected by human immunodeficiency virus (HIV) genetic preposition, a malignant disease associated with the amyloid deposited on the heart or other organs, high blood pressure, untreated hyperthyroidism, and vitamin b2 deficiency are some of the most prevalent factors found in patients with cardiotoxicity.
Most common symptoms of cardiotoxicity are associated with not enough blood circulation in the body such as tiredness and fatigue, a long-term (chronic) cough, shortness of breath, floating due to the enlarged heart muscle, abnormal heart or lung sounds and swelling in your hands, feet, or unusual weight gain.
Conventionally, treatment of cardiotoxicity is totally depending on the types of the disease including
Beta-blockers, ACE inhibitors induce (widen) arterial dilation and improvement of the blood flow and diuretics.
Some researchers in examining the risk of cardiotoxicity in patients with chemotherapy wrote, "Age and preexisting left ventricular dysfunction have been identified most consistently as being associated with the development of clinical heart failure or a worsening of left ventricular function with chemotherapy".
And, ""Other cardiovascular conditions, including hypertension, diabetes, and coronary artery disease, are also associated with the risk of cardiotoxicity".
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In finding a potent ingredient that processes cardio-protective activity researchers examined the effects of extracts from edible wild onion species, Allium flavum, and Allium carinatum, which reduce side effects of cytostatic doxorubicin (Dox).
In human hepatoma (HepG2) and lung carcinoma (A549) cells, the methanol extracts exhibited high levels of antioxidant activity and worked synergistically to increased Dox anticancer activity, without affecting the health of normal cells.
Furthermore, antioxidative enzyme levels such as catalase and superoxide dismutases in the cancer cells were also suppressed by the chemicals, compared to normal cells upon applied treatments.
In the toxicity assays on the zebrafish model, the chemical extracts isolated from edible wild onion species process lower toxicity compared to Dox, with no teratogenic effects at applied doses.
Most importantly, the extracts not only successfully protect the Dox-treated embryos from life-threatening cardiomyopathy but also reduced developmental toxicity and neutropenia. in the zebrafish model.
Additionally, the extracts also processed a higher anti-angiogenic activity compared to those of antiangiogenic drugs such as sunitinib or auranofin.
Taken together, onion extracts may be considered a remedy for the prevention and treatment of cardio-toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Wild edible onions - Allium flavum and Allium carinatum - successfully prevent adverse effects of chemotherapeutic drug doxorubicin by Aleksandar P1, Dragana MĆ2, Nebojša J3, Biljana N3, Nataša S4, Branka V5, Jelena KV. (PubMed)
(2) Risk factors for chemotherapy-related cardiac toxicity by Polonsky TS1, DeCara JM. (PubMed)
#Ginger #Extract Inibits Inflammatory Markers Associated with the Onset of #MetabolicDysfunction in Obese, Researchers Say
Kyle J. Norton
Scientists may have found a pungent spice that processes the potential to reverse metabolic dysfunction, according to studies.
Metabolic dysfunction is a medical condition characterized by the improper function of the liver or pancreas.
In some cases, metabolic dysfunction may also be caused by enzyme deficiency due to a defective gene, including Antitrypsin (AAT) deficiency, a common metabolic liver disease that affects infants, children, and adults.
The liver, the large organ in humans plays a critical role in breaking down old or damaged blood cells. and a central role in all metabolic processes, including fat metabolism by breaking down fat to energy for the body's needs.
On the other hand, the pancreas also converts the food we eat into energy for the body's cells by regulating blood glucose through the production of insulin.
Dysfunction of one of the 2 organs not only has a strong impact on the energy levels in the body but also increases the risk of diabetes and nonalcoholic liver disease.
According to the statistics provided by the Centers for Diseases Control and Prevention, in the US, among adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%. The rise of metabolic dysfunction is probably associated with widespread obesity in the general population, some researchers suggested.
The risk factors associated with the onset of metabolic dysfunction include workers exposed to natural asbestos and mixed asbestos stock dust, improper nutrition, excessive intake of food with a high content of free sugar, saturated fatty acids, and common salt with a lack of chicken meat, cereals, fish, vegetables, fruits, and cultured milk foods in the diet and excessive body weight.
Most people with metabolic dysfunction do not experience any symptoms. However, if you have a large waist circumference and experience symptoms of high blood glucose, increased thirst and urination, fatigue, and blurred vision, you may have a metabolic disorder. Please check with your doctor to rule out the possibility.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the modulation of metabolism evaluated the effects and the mechanisms of ginger extract intake in the metabolic disturbances animal model. Mice selected for the study were induced metabolic dysfunction by a high-refined carbohydrate (HC) diet.
Ginger extract at doses of 200, 600, and 1800 mg/kg supplemented in the daily food of obese Balb/c mice for an 8-week showed a metabolic protective effect by preventing the increase of adiposity induced by HC diet, improving lipid profile, and promoting the decrease of inflammatory markers.
Furthermore, treated mice also exerted a decrease in the recruitment of cells visualized in vivo in the microvasculature of adipose tissue, a decrease in inflammatory cytokines, and an increase in adiponectin serum levels.
The finding suggested that ginger processes anti-metabolic dysfunction in obese mice induced by a long-term high-refined carbohydrate (HC) diet.
In order to reveal more information about ginger anti-metabolic syndrome activity, used in traditional medicine, researchers examined the herbal effects on hyperlipidemia, hyperglycemia, oxidative stress, and inflammation.
Ginger showed a potency activity in reducing the onset of metabolic syndrome through
mediating the several transcription factors associated with the metabolic function, including activated glucose and fatty acid uptake.
The results indicated the beneficial effects of ginger on obesity and related complications in MetS.
Taken together, ginger may be considered a functional remedy for the prevention and treatment of metabolic dysfunction, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale Rosc.) Ameliorated Metabolic and Inflammatory Dysfunction Induced by High-Refined Carbohydrate-Containing Diet in Mice by Oliveira CT1, Lacerda DR1, Zicker MC1, Martins LB1, Teixeira MM2, Bello de Araujo RL1, Ferreira AVM. (PubMed)
(2) Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review by Wang J1,2, Ke W1, Bao R1, Hu X1,2, Chen F. (PubMed)
(3) [Risk factors and development of metabolic disorders in workers of "Uralasbest" enterprise][Article in Russian] by Prianichnikova NI, Mazhaeva TV, Dubenko SÉ, Obukhova TIu, Chirkova IA.(PubMed)
(4) Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988–2012 by ORIGINAL RESEARCH — Volume 14 — March 16, 2017. (CDC)
Scientists may have found a pungent spice that processes the potential to reverse metabolic dysfunction, according to studies.
Metabolic dysfunction is a medical condition characterized by the improper function of the liver or pancreas.
In some cases, metabolic dysfunction may also be caused by enzyme deficiency due to a defective gene, including Antitrypsin (AAT) deficiency, a common metabolic liver disease that affects infants, children, and adults.
The liver, the large organ in humans plays a critical role in breaking down old or damaged blood cells. and a central role in all metabolic processes, including fat metabolism by breaking down fat to energy for the body's needs.
On the other hand, the pancreas also converts the food we eat into energy for the body's cells by regulating blood glucose through the production of insulin.
Dysfunction of one of the 2 organs not only has a strong impact on the energy levels in the body but also increases the risk of diabetes and nonalcoholic liver disease.
According to the statistics provided by the Centers for Diseases Control and Prevention, in the US, among adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%. The rise of metabolic dysfunction is probably associated with widespread obesity in the general population, some researchers suggested.
The risk factors associated with the onset of metabolic dysfunction include workers exposed to natural asbestos and mixed asbestos stock dust, improper nutrition, excessive intake of food with a high content of free sugar, saturated fatty acids, and common salt with a lack of chicken meat, cereals, fish, vegetables, fruits, and cultured milk foods in the diet and excessive body weight.
Most people with metabolic dysfunction do not experience any symptoms. However, if you have a large waist circumference and experience symptoms of high blood glucose, increased thirst and urination, fatigue, and blurred vision, you may have a metabolic disorder. Please check with your doctor to rule out the possibility.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the modulation of metabolism evaluated the effects and the mechanisms of ginger extract intake in the metabolic disturbances animal model. Mice selected for the study were induced metabolic dysfunction by a high-refined carbohydrate (HC) diet.
Ginger extract at doses of 200, 600, and 1800 mg/kg supplemented in the daily food of obese Balb/c mice for an 8-week showed a metabolic protective effect by preventing the increase of adiposity induced by HC diet, improving lipid profile, and promoting the decrease of inflammatory markers.
Furthermore, treated mice also exerted a decrease in the recruitment of cells visualized in vivo in the microvasculature of adipose tissue, a decrease in inflammatory cytokines, and an increase in adiponectin serum levels.
The finding suggested that ginger processes anti-metabolic dysfunction in obese mice induced by a long-term high-refined carbohydrate (HC) diet.
In order to reveal more information about ginger anti-metabolic syndrome activity, used in traditional medicine, researchers examined the herbal effects on hyperlipidemia, hyperglycemia, oxidative stress, and inflammation.
Ginger showed a potency activity in reducing the onset of metabolic syndrome through
mediating the several transcription factors associated with the metabolic function, including activated glucose and fatty acid uptake.
The results indicated the beneficial effects of ginger on obesity and related complications in MetS.
Taken together, ginger may be considered a functional remedy for the prevention and treatment of metabolic dysfunction, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale Rosc.) Ameliorated Metabolic and Inflammatory Dysfunction Induced by High-Refined Carbohydrate-Containing Diet in Mice by Oliveira CT1, Lacerda DR1, Zicker MC1, Martins LB1, Teixeira MM2, Bello de Araujo RL1, Ferreira AVM. (PubMed)
(2) Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review by Wang J1,2, Ke W1, Bao R1, Hu X1,2, Chen F. (PubMed)
(3) [Risk factors and development of metabolic disorders in workers of "Uralasbest" enterprise][Article in Russian] by Prianichnikova NI, Mazhaeva TV, Dubenko SÉ, Obukhova TIu, Chirkova IA.(PubMed)
(4) Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988–2012 by ORIGINAL RESEARCH — Volume 14 — March 16, 2017. (CDC)
#Onion Inversely is Associated with the Risk of Upper Aerodigestive Tract (#UADT) Cancer, According to Studies
Kyle J. Norton
The aerodigestive tract is the combined organs and tissues of the respiratory tract and the upper part of the digestive tract including the lip, tongue, major salivary glands, gums and adjacent oral cavity tissues, the floor of the mouth, tonsils, oropharynx, nasopharynx, hypopharynx and other oral regions, nasal cavity, accessory sinuses, middle ear, and larynx.
Cancer is a class of diseases characterized by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
Upper aerodigestive tract cancer is a type of invasive cancer that starts in the cell on the surface of the inner lining of the aerodigestive tract before proliferating to a deeper layer to form a tumor.
According to the statistics provided by the Scottish Health Service, upper aerodigestive tract cancer accounts for approximately 4% of all malignancies with cancers of salivary glands, gums, nasopharynx, nasal cavities, and accessory sinuses. Epidermoid carcinomas account for greater than 95% of all cases.
Epidemiologically, aging, male gender, and ethnicity are some of the most common prevalent factors associated with the incidences.
The 5-year relative survival rate of the upper aerodigestive tract (UADT) was approximately 50%, depending on the type of UADT.
Dr. F. Bravi, the lead scientist in the examination of the diet patterns in the risk of UADT wrote, "
The most consistent findings are the beneficial role of a dietary pattern based on fruit and vegetables or nutrients mostly contained in such foods and the unfavorable role of an alcohol drinker pattern. A possible unfavorable role of patterns based on meats and animal products emerged as well".
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
In finding a potent compound for the prevention and treatment of gastrointestinal tract cancer, researchers examined the effect of total allium, garlic, and onion intake on the risk of cancer of the upper aerodigestive tract (UADT).
The study identified 21 case-control and four cohort studies through the searching data of published observational studies, using a meta-analytic approach and random-effects models.
* The overall relative risks (RR) for the squamous cell carcinoma of the UADT were 0.72 (95% CI 0.57-0.91) for onion for the highest versus the lowest consumption.
* Onion showed a strong inverse relation in case-control studies with an RR of 0.56.
* In Chinese studies onion showed a lesser effect compared to garlic for esophageal than for head and neck cancers.
* Believe it or not, there was no relation between allium vegetable intake and adenocarcinoma of the esophagus.
These results strongly suggested that the onion process has a significant anti-upper aerodigestive tract (UADT) cancer effect, depending on the type of gastrointestinal tract cancer.
Collectively, researchers after taking other factors into account wrote, "We found a moderate inverse association between allium vegetable intake and the risk of squamous cell carcinoma of the UADT in case-control studies".
Taken together, onion processed with a higher amount of onionin A (ONA) may be considered a remedy for the treatment of upper aerodigestive tract cancer effect, depending on the types of UADT, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Allium vegetables and upper aerodigestive tract cancers: a meta-analysis of observational studies by Guercio V1, Turati F2, La Vecchia C1, Galeone C2, Tavani A. (PubMed)
(2) In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine by Ramakrishna Rao R1, Platel K, Srinivasan K. (PubMed)
(3) Upper aerodigestive tract cancers by Muir C1, Weiland L. (PubMed)
(4) Dietary patterns and upper aerodigestive tract cancers: an overview and review by
Bravi V. Edefonti G. Randi M. Ferraroni C. La Vecchia A. Decarli (Annuals of Oncology)
The aerodigestive tract is the combined organs and tissues of the respiratory tract and the upper part of the digestive tract including the lip, tongue, major salivary glands, gums and adjacent oral cavity tissues, the floor of the mouth, tonsils, oropharynx, nasopharynx, hypopharynx and other oral regions, nasal cavity, accessory sinuses, middle ear, and larynx.
Cancer is a class of diseases characterized by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
Upper aerodigestive tract cancer is a type of invasive cancer that starts in the cell on the surface of the inner lining of the aerodigestive tract before proliferating to a deeper layer to form a tumor.
According to the statistics provided by the Scottish Health Service, upper aerodigestive tract cancer accounts for approximately 4% of all malignancies with cancers of salivary glands, gums, nasopharynx, nasal cavities, and accessory sinuses. Epidermoid carcinomas account for greater than 95% of all cases.
Epidemiologically, aging, male gender, and ethnicity are some of the most common prevalent factors associated with the incidences.
The 5-year relative survival rate of the upper aerodigestive tract (UADT) was approximately 50%, depending on the type of UADT.
Dr. F. Bravi, the lead scientist in the examination of the diet patterns in the risk of UADT wrote, "
The most consistent findings are the beneficial role of a dietary pattern based on fruit and vegetables or nutrients mostly contained in such foods and the unfavorable role of an alcohol drinker pattern. A possible unfavorable role of patterns based on meats and animal products emerged as well".
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
In finding a potent compound for the prevention and treatment of gastrointestinal tract cancer, researchers examined the effect of total allium, garlic, and onion intake on the risk of cancer of the upper aerodigestive tract (UADT).
The study identified 21 case-control and four cohort studies through the searching data of published observational studies, using a meta-analytic approach and random-effects models.
* The overall relative risks (RR) for the squamous cell carcinoma of the UADT were 0.72 (95% CI 0.57-0.91) for onion for the highest versus the lowest consumption.
* Onion showed a strong inverse relation in case-control studies with an RR of 0.56.
* In Chinese studies onion showed a lesser effect compared to garlic for esophageal than for head and neck cancers.
* Believe it or not, there was no relation between allium vegetable intake and adenocarcinoma of the esophagus.
These results strongly suggested that the onion process has a significant anti-upper aerodigestive tract (UADT) cancer effect, depending on the type of gastrointestinal tract cancer.
Collectively, researchers after taking other factors into account wrote, "We found a moderate inverse association between allium vegetable intake and the risk of squamous cell carcinoma of the UADT in case-control studies".
Taken together, onion processed with a higher amount of onionin A (ONA) may be considered a remedy for the treatment of upper aerodigestive tract cancer effect, depending on the types of UADT, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Allium vegetables and upper aerodigestive tract cancers: a meta-analysis of observational studies by Guercio V1, Turati F2, La Vecchia C1, Galeone C2, Tavani A. (PubMed)
(2) In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine by Ramakrishna Rao R1, Platel K, Srinivasan K. (PubMed)
(3) Upper aerodigestive tract cancers by Muir C1, Weiland L. (PubMed)
(4) Dietary patterns and upper aerodigestive tract cancers: an overview and review by
Bravi V. Edefonti G. Randi M. Ferraroni C. La Vecchia A. Decarli (Annuals of Oncology)
#Ginger Inhibits the Proteins Associated with the Onset of #ProstateCancer, Scientists Reveal
Kyle J. Norton
Scientists may have found a pungent spice that processes a potential for the prevention and treatment of prostate cancer, some studies suggested.
Prostate cancer is a chronic condition caused by cell growth irregularly and disorderly in the prostate tissue due to the alternation of DNA.
Prostate cancer is a slow-growth of cancer and can be detected during annual rectum exams.
At the early stage, prostate cancer cell which has grown on the surface of the inner lining of the prostate does not cause any symptoms due to the very small size of the tumor.
However, at the later stage, the large tumor size may suppress the nearby blood vessels and nerve cells, leading to internal bleeding and severe pain. Also, cancer cells may also travel a distance away from the stomach to infect other healthy tissue and organs, leading to secondary metastasis.
Common sites metastases of prostate cancer are bone, lymph nodes, lung, and liver.
Researchers do not know the exact causes of prostate cancer. However, they do know the increase in age, family and personal history, ethnicity, genetic preposition, a poor diet, being overweight or obesity are some of the prevalent risk factors of prostate cancer.
According to the Canadian Cancer Society, in 2017, 21,300 men were diagnosed with prostate cancer, which represented 21% of all new cancer cases and 4,100 men died from prostate cancer, and 10% of all cancer deaths.
The 5 years survival rate of localized prostate cancer is 100% and 98% of that of survivors are alive after 10 years compared to the advanced stage of only 31%.
Some researchers concerned about the widespread prostate cancer in North America, northwestern Europe, Australia, and on Caribbean islands compared to Asia, Africa, Central America, and South America, said, "One of the most striking characteristics of prostate cancer is the degree of geographic variation in its patterns of occurrence and progression; this variation is apparent at local, national, and international levels".
And "the known factors influencing the biology and epidemiology of prostate cancer and some of the ways in which findings to date have benefited from geography".
The results strongly indicated there must be something happening in the Western world that does not found in the East and Africa, Central America, and South America.
Some researchers suggested it may be the Western diet.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In the concern of prostate cancer risk in men in the Western world and its related mortality and morbidity, researchers in the cancer team at The University of Texas at Austin examined the anti-prostate cancer effect of 6-Shogaol (6-SHO), a potent bioactive compound in ginger (Zingiber officinale Roscoe).
Injection of the bioactive compound effectively reduced survival and induced apoptosis of cultured human (LNCaP, DU145, and PC3) and mouse (HMVP2) prostate cancer cells.
6-SHO reduced the expression of pro-inflammatory cytokines in the activation of the proteins involved in cell proliferation and the capacity for metastasis.
Furthermore, 6-SHO also inhibited the expression of cytokines in the stimulation of proteins and genes associated with the anti-apoptotic activity and tumor cell survival.
6-SHO was more effective than two other compounds found in ginger, 6-gingerol, and 6-paradol at reducing the survival of prostate cancer cells.
Moreover, 6-SHO also showed significant tumor growth inhibitory activity in an allograft model in HMVP2 cells.
In other words, 6-SHO inhibited prostate cancer through several mechanisms, including chemokine, cytokine, cell cycle, apoptosis, and genes.
Dr. Saha A and colleagues wrote in the final report, "6-SHO may have potential as a chemopreventive and/or therapeutic agent for prostate cancer".
Additionally, in order to reveal more information about ginger as a promising chemopreventive agent, researchers examined ginger extract (GE) growth-inhibitory and death-inductive effects in a spectrum of prostate cancer cells.
Injection of the extract showed a significant effect on perturbed cell-cycle progression, impaired reproductive capacity, modulated cell-cycle, and apoptosis in human prostate cancer cells.
Daily oral feeding of 100 mg/kg body weight of GE inhibited growth and progression of PC-3 xenografts by approximately 56 % in nude mice, observed by the tumor tissue from GE-treated mice compared to controls.
Most importantly, GE is safe as toxicity is not detected in normal, rapidly dividing tissues such as the gut and bone marrow.
Taken altogether, ginger-processed 6-Shogaol (6-SHO) may be considered a functioning remedy for the prevention and combined with the primary medicine for the treatment of prostate cancer with no side effects, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 year
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) 6-Shogaol from dried ginger inhibits the growth of prostate cancer cells both in vitro and in vivo through inhibition of STAT3 and NF-κB signaling by Saha A1, Blando J1, Silver E1, Beltran L1, Sessler J1, DiGiovanni J. (PubMed)
(2) Benefits of whole ginger extract in prostate cancer by Prasanthi Karna,1 Sharmeen Chagani,1 Sushma R. Gundala,1 Padmashree C. G. Rida,1Ghazia Asif,1 Vibhuti Sharma,1 Meenakshi V. Gupta,2 and Ritu Aneja. (PubMed)
(3) What can geography tell us about prostate cancer? by Klassen AC1, Platz EA. (PubMed)
Scientists may have found a pungent spice that processes a potential for the prevention and treatment of prostate cancer, some studies suggested.
Prostate cancer is a chronic condition caused by cell growth irregularly and disorderly in the prostate tissue due to the alternation of DNA.
Prostate cancer is a slow-growth of cancer and can be detected during annual rectum exams.
At the early stage, prostate cancer cell which has grown on the surface of the inner lining of the prostate does not cause any symptoms due to the very small size of the tumor.
However, at the later stage, the large tumor size may suppress the nearby blood vessels and nerve cells, leading to internal bleeding and severe pain. Also, cancer cells may also travel a distance away from the stomach to infect other healthy tissue and organs, leading to secondary metastasis.
Common sites metastases of prostate cancer are bone, lymph nodes, lung, and liver.
Researchers do not know the exact causes of prostate cancer. However, they do know the increase in age, family and personal history, ethnicity, genetic preposition, a poor diet, being overweight or obesity are some of the prevalent risk factors of prostate cancer.
According to the Canadian Cancer Society, in 2017, 21,300 men were diagnosed with prostate cancer, which represented 21% of all new cancer cases and 4,100 men died from prostate cancer, and 10% of all cancer deaths.
The 5 years survival rate of localized prostate cancer is 100% and 98% of that of survivors are alive after 10 years compared to the advanced stage of only 31%.
Some researchers concerned about the widespread prostate cancer in North America, northwestern Europe, Australia, and on Caribbean islands compared to Asia, Africa, Central America, and South America, said, "One of the most striking characteristics of prostate cancer is the degree of geographic variation in its patterns of occurrence and progression; this variation is apparent at local, national, and international levels".
And "the known factors influencing the biology and epidemiology of prostate cancer and some of the ways in which findings to date have benefited from geography".
The results strongly indicated there must be something happening in the Western world that does not found in the East and Africa, Central America, and South America.
Some researchers suggested it may be the Western diet.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In the concern of prostate cancer risk in men in the Western world and its related mortality and morbidity, researchers in the cancer team at The University of Texas at Austin examined the anti-prostate cancer effect of 6-Shogaol (6-SHO), a potent bioactive compound in ginger (Zingiber officinale Roscoe).
Injection of the bioactive compound effectively reduced survival and induced apoptosis of cultured human (LNCaP, DU145, and PC3) and mouse (HMVP2) prostate cancer cells.
6-SHO reduced the expression of pro-inflammatory cytokines in the activation of the proteins involved in cell proliferation and the capacity for metastasis.
Furthermore, 6-SHO also inhibited the expression of cytokines in the stimulation of proteins and genes associated with the anti-apoptotic activity and tumor cell survival.
6-SHO was more effective than two other compounds found in ginger, 6-gingerol, and 6-paradol at reducing the survival of prostate cancer cells.
Moreover, 6-SHO also showed significant tumor growth inhibitory activity in an allograft model in HMVP2 cells.
In other words, 6-SHO inhibited prostate cancer through several mechanisms, including chemokine, cytokine, cell cycle, apoptosis, and genes.
Dr. Saha A and colleagues wrote in the final report, "6-SHO may have potential as a chemopreventive and/or therapeutic agent for prostate cancer".
Additionally, in order to reveal more information about ginger as a promising chemopreventive agent, researchers examined ginger extract (GE) growth-inhibitory and death-inductive effects in a spectrum of prostate cancer cells.
Injection of the extract showed a significant effect on perturbed cell-cycle progression, impaired reproductive capacity, modulated cell-cycle, and apoptosis in human prostate cancer cells.
Daily oral feeding of 100 mg/kg body weight of GE inhibited growth and progression of PC-3 xenografts by approximately 56 % in nude mice, observed by the tumor tissue from GE-treated mice compared to controls.
Most importantly, GE is safe as toxicity is not detected in normal, rapidly dividing tissues such as the gut and bone marrow.
Taken altogether, ginger-processed 6-Shogaol (6-SHO) may be considered a functioning remedy for the prevention and combined with the primary medicine for the treatment of prostate cancer with no side effects, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 year
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) 6-Shogaol from dried ginger inhibits the growth of prostate cancer cells both in vitro and in vivo through inhibition of STAT3 and NF-κB signaling by Saha A1, Blando J1, Silver E1, Beltran L1, Sessler J1, DiGiovanni J. (PubMed)
(2) Benefits of whole ginger extract in prostate cancer by Prasanthi Karna,1 Sharmeen Chagani,1 Sushma R. Gundala,1 Padmashree C. G. Rida,1Ghazia Asif,1 Vibhuti Sharma,1 Meenakshi V. Gupta,2 and Ritu Aneja. (PubMed)
(3) What can geography tell us about prostate cancer? by Klassen AC1, Platz EA. (PubMed)
Tomato Supplementation Inhibits Hepatic Markers Through its Anti-Inflammatory and Antioxidant Activity and Lipid Metabolism
Kyle J. Norton
A hepatic marker is a blood test that measures the function of the liver. In other words, according to the blood test results, your doctor may know the severity of the liver damage.
The liver is the largest internal organ in the body which plays a critical role to filter out blood from the digestive system before passing them to other parts of the body.
Furthermore, the liver also produces bile which has a strong impact on the building of cell membranes, production of steroid hormones and vitamin D, and aiding the digestive system in the absorption of nutrients.
Liver transaminases aspartate transaminase (AST) and alanine transaminase (ALT) are some of the liver markers used by researchers to measure liver injury in a patient with some degree of intact liver function.
Aspartate transaminase (AST) is an enzyme found primarily in the liver and kidney. High levels of ALT are associated with liver damage. ALT screening is used often in patients with
liver disease.
Alanine aminotransferase (ALT) is a liver enzyme. increased levels of ALT have been found in patients with liver damage.
Other liver enzymes such as Alkaline phosphatase (ALP) and Gamma-glutamyl transpeptidase (GGT) also have a similar effect as seen in ALT and AST.
More precisely, elevated liver enzymes is an indication of liver inflammation or cell damage.
Dr. Edoardo G. Giannin, the lead scientist in the explanation of liver enzyme alternation, wrote, "Abnormal liver enzyme levels may signal liver damage or alteration in bile flow. Liver enzyme alteration may be either the accompanying biochemical picture in a patient with symptoms or signs suggestive of liver disease or an isolated, unexpected finding in a patient who has undergone a wide range of laboratory tests for a nonhepatic disease or for minor, vague complaints".
And, "The pattern of enzyme abnormality, interpreted in the context of the patient's characteristics, can aid in directing the subsequent diagnostic work-up. Awareness of the prevalence of the determining liver disease in specific populations and of possible hepatic involvement during systemic illnesses or drug therapies may help the clinician identify the cause of alterations efficiently".
The results strongly suggested that testing hepatic markers of patients with liver disease may be helpful to identify the causes.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods which process liver-protective effects, researchers examined the effect of dry tomato peel (DTP) on hepatic markers in a high-saturated-fat (HSF) diet animal model for 12 weeks.
The study included 40 8 weeks old, weighing 22.2±1.0 g) BALB/c male mice (n=40) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the tested assays, without supplements with DTP, HSF/HC diet-treated mice showed significantly increased body weight gain, adipose tissue weight, insulin resistance, and lipid peroxidation in the liver as well as the onset of liver steatosis and inflammation.
Upon the injection of DTP, HSF/HC diet mice demonstrated a significant increase in plasma lycopene concentration and reduced markers associated with metabolic syndrome developing.
In other words, DTP inhibited the liver damage and injury marker through its anti-inflammatory and antioxidant activity and lipid metabolism
Taken together, tomatoes processed with a high amount of lycopene may be considered a dietary supplement for liver protection, pending to large sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Feeding tomato and broccoli powders enriched with bioactives improves bioactivity markers in rats by Liu AG1, Volker SE, Jeffery EH, Erdman JW Jr. (PubMed)
(3) Liver enzyme alteration: a guide for clinicians by Edoardo G. Giannini, Roberto Testa, and Vincenzo Savarino. (PMC)
A hepatic marker is a blood test that measures the function of the liver. In other words, according to the blood test results, your doctor may know the severity of the liver damage.
The liver is the largest internal organ in the body which plays a critical role to filter out blood from the digestive system before passing them to other parts of the body.
Furthermore, the liver also produces bile which has a strong impact on the building of cell membranes, production of steroid hormones and vitamin D, and aiding the digestive system in the absorption of nutrients.
Liver transaminases aspartate transaminase (AST) and alanine transaminase (ALT) are some of the liver markers used by researchers to measure liver injury in a patient with some degree of intact liver function.
Aspartate transaminase (AST) is an enzyme found primarily in the liver and kidney. High levels of ALT are associated with liver damage. ALT screening is used often in patients with
liver disease.
Alanine aminotransferase (ALT) is a liver enzyme. increased levels of ALT have been found in patients with liver damage.
Other liver enzymes such as Alkaline phosphatase (ALP) and Gamma-glutamyl transpeptidase (GGT) also have a similar effect as seen in ALT and AST.
More precisely, elevated liver enzymes is an indication of liver inflammation or cell damage.
Dr. Edoardo G. Giannin, the lead scientist in the explanation of liver enzyme alternation, wrote, "Abnormal liver enzyme levels may signal liver damage or alteration in bile flow. Liver enzyme alteration may be either the accompanying biochemical picture in a patient with symptoms or signs suggestive of liver disease or an isolated, unexpected finding in a patient who has undergone a wide range of laboratory tests for a nonhepatic disease or for minor, vague complaints".
And, "The pattern of enzyme abnormality, interpreted in the context of the patient's characteristics, can aid in directing the subsequent diagnostic work-up. Awareness of the prevalence of the determining liver disease in specific populations and of possible hepatic involvement during systemic illnesses or drug therapies may help the clinician identify the cause of alterations efficiently".
The results strongly suggested that testing hepatic markers of patients with liver disease may be helpful to identify the causes.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods which process liver-protective effects, researchers examined the effect of dry tomato peel (DTP) on hepatic markers in a high-saturated-fat (HSF) diet animal model for 12 weeks.
The study included 40 8 weeks old, weighing 22.2±1.0 g) BALB/c male mice (n=40) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the tested assays, without supplements with DTP, HSF/HC diet-treated mice showed significantly increased body weight gain, adipose tissue weight, insulin resistance, and lipid peroxidation in the liver as well as the onset of liver steatosis and inflammation.
Upon the injection of DTP, HSF/HC diet mice demonstrated a significant increase in plasma lycopene concentration and reduced markers associated with metabolic syndrome developing.
In other words, DTP inhibited the liver damage and injury marker through its anti-inflammatory and antioxidant activity and lipid metabolism
Taken together, tomatoes processed with a high amount of lycopene may be considered a dietary supplement for liver protection, pending to large sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Feeding tomato and broccoli powders enriched with bioactives improves bioactivity markers in rats by Liu AG1, Volker SE, Jeffery EH, Erdman JW Jr. (PubMed)
(3) Liver enzyme alteration: a guide for clinicians by Edoardo G. Giannini, Roberto Testa, and Vincenzo Savarino. (PMC)
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