Kyle J. Norton
Green tea may have a therapeutic and positive effect in reducing the risk and treatment of gastric ulcer, some scientists suggested.
Gastric ulcers are sores that develop in the lining of the stomach as a result of bacterial infection or by overproduction of stomach acid. In other words, gastric ulcer is a condition characterized by open sores developed in the stomach, affecting the function of the stomach.
There are a set of factors that cause a gastric ulcer, including the infection of Helicobacter pylori (H. pylori), frequent use of anti-inflammatory medicine, aging, smoking and excessive alcohol drinking
Some researchers suggested that people who have radiation therapy for stomach cancer are also at a higher risk to gastric ulcer development.
According to the study "Are genetic influences on peptic ulcer dependent or independent of genetic influences for Helicobacter pylori infection?" by the Veterans Affairs Medical Center and Baylor College of Medicine. "Genetic influences are of moderate importance for liability to peptic ulcer disease. Genetic influences for peptic ulcer are independent of genetic influences important for acquiring H. pylori infection".
If you are experiencing the symptoms of dull pain in the stomach. weight loss. refuse to eat because of pain. persistent gastrointestinal discomforts, acid reflux, and heartburn, you may have a gastric ulcer. Please make sure that you check with your doctor to rule out the possibility.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
In the testing of healing of the hydroalcoholic extract including ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) from green tea (GEt) in the risk of gastric ulcer induced by application of 80 % acetic acid on serosal mucosa of rats, researchers showed that application of the extract after 7 days inhibited ulcer area by exhibiting the antioxidant activity in reducing the free radical overexpression.
Furthermore, application of the hydroalcoholic extract also inhibited the oxidative stress that cause gastric damage by injection of acetic acid by enhancing the production of antioxidant enzyme GSH, superoxide dismutase (SOD) and Glutathione-S-transferase (GST) enzymes and ameliorating the production of lipid hydroperoxides (LOOH), a free radical in precipitated ulcer development by withdrawing electrons from the lipids in cell membranes.
Additional analysis also suggested that rats fed with green tea (GEt) improved the capacity of mucin content in gastric juice which has been found at reduced levels in rats with an ulcer after infection with acetic acid.
Interestingly, injection of green tea (GEt) also decreased inflammatory infiltration of Myeloperoxidase (MPO) and N-acetylglucosaminidase (NAG) which has been used as biomarkers in the measurement of severity in some diseases including gastric ulcer.
Importantly, the application did not alter gastric acid secretion and induced acute toxicity.
Dr. Borato DG, the lead author, after taking into account the con-founders said, "GEt had a pronounced antiulcer effect, possibly through maintenance of mucin content and reduction of inflammation and oxidative stress".
Other polyphenol compound L-Theanine, isolated from green tea on NSAID (indomethacin)-induced maximum ulceration in the stomach on the third day at dose of 18 mg/kg inhibited the expression of the overproduction of reactive oxygen species (ROS) in the induction of lipid peroxidation, oxidation and protein carbonylation which is considered one of the most harmful irreversible oxidative protein that cause damage to the stomach.
The application also reduced expression of type 1 T helper (Th1) cells in the production of inflammatory cytokines, interferon-gamma, interleukin (IL)-2, and tumor necrosis factor (TNF)-beta, in the facilitated immune response in exhibiting inflammation in the acute stomach damage infection.
Additionally, L-Theanine also increased the levels of total thiol in the stomach tissue, and mucin content in the gastric juice. The enhanced antioxidant levels not only improve digestion but also protect the stomach against damage by foreign substances.
Moreover, at a higher dose of 40 mg/kg b.w. At 10 mg/kg b.w., Dr. Chatterjee S, the lead author said, "L-theanine significantly alleviated the adverse oxidative effect of indomethacin through enhanced synthesis of PGE2 by modulation of cyclooxygenase-1 and 2 [COX-1 and COX-2] expression, Th1/Th2 cytokine balance, and restoration of cellular antioxidant status at the gastric ulcer margin".
Taken together, tea with abundant bioactive polyphenols may be considered functional food for the treatment of gastric ulcers without causing any adverse effects.
However, high doses and long-term applications of green tea supplements were associated with acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea(Camellia sinensis (L.) Kuntze) on chronic gastric ulcers by Borato DG1, Scolaro CT2, Maria-Ferreira D1, da Silva LM1, de Souza LM2, Iacomini M2, Werner MF1, Baggio CH3. (PubMed)
(2) L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin by Chatterjee S1, Chatterjee A, Roy S, Bera B, Bandyopadhyay SK. (PubMed)
Wednesday, 5 July 2023
#Carrots Inhibit the Risk of #ProstateCancer Through Thiei Anti-Proliferative and Initiated Cancer Cell Apoptosis Activity, Researchers Say
Kyle J. Norton
Carrots may have a profound and positive effect in reduced risk, progression, and treatment of prostate cancer, some scientists suggested.
Prostate cancer is a condition characterized by cell growth disorderly and uncontrollably in prostate tissue. At the later stage, the cancerous cells may infect other healthy tissue and organ a distance away from the original site.
Carrot, a root vegetable with orange color is a sub spice of Daucus carota, belongings to the family Apiaceae, native to Asia and Europe.
The study to verify the effect of carrots on the risk of prostate cancer by reviewing the publication of literature in August 2013 of PubMed, EMBASE, Scopus, Web of Science, the Cochrane Register, and the Chinese National Knowledge Infrastructure databases, and the references of the retrieved articles, researchers at the Zhejiang University found that intake of carrot demonstrated a significantly reduced risk of prostate cancer with the odd ratio of .82 in compared to the non-serving group.
The risk of prostate cancer was decreased by 5% and 6% in intake of a weekly portion of 10 g of carrot increment without precipitating adverse effects.
Dr. Xu X, the lead author suggested that the intake of carrots frequently with limited volume may have a profound effect in reducing prostate cancer risk.
Further analysis of the potential effect of lycopene extract found abundantly in tomato and carrot in decreased risk of onset and treatment of prostate cancer indicated that lycopene inhibited prostate cancer proliferation through modulated the expression of PI3K/Akt pathway prostate cancer cell lines in regulating cancerous cellular functions including metabolism, growth, proliferation.
Dysfunction of the PI3K/Akt pathway was associated with a number of human diseases including cancer, diabetes, cardiovascular disease, and neurological diseases.
Moreover, the application of lycopene also displayed a strong effect in inhibiting the proliferation of androgen-dependent prostateLNCaP cancer cells through the activation of the peroxisome proliferator-activated receptor gamma (PPARγ) with the function to act as a tumor suppressor in prostate cells due to its activity in the induction of agonist ligands in inhibited growth of prostate cancer cells.
Additionally, the phytochemical also expressed a significant activity in exhibiting the liver X receptor alpha (LXRα) in reducing the proliferation of human oral cancer cells by promoting cell cycle arrest through increased expression of the cyclin-dependent kinase inhibitor p27, a tumor suppressor and promoted function of extracellular ATP-binding cassette transporter 1 (ABCA1) pathway in inhibited tumor growth through modulation of macrophage function within the tumor, and in establishing a link between cholesterol homeostasis and cancer.
Application of lycopene (10 μM) in the presence of a specific antagonist of PPARγ (GW9662) or LXRα (GGPP) exerted a huge effect in reduced liver X receptor α knockdown in the induction of resistance against LXRα in promoted the proliferation of DU145 cells.
Interestingly, lycopene in combination with the LXRα agonist T0901317, a potent chemical compound used in assays, exhibited anti-prostate cell proliferative activity through interaction with protein expression of PPARγ, LXRα, and ABCA1 in initiated cancer cell apoptosis.
In conclusion, Dr. Yang CM, the lead author said, "These results demonstrate that lycopene can inhibit DU145 cell proliferation via PPARγ-LXRα-ABCA1 pathway and that lycopene and T0901317 exhibit synergistic effects".
The result findings strongly suggested that long-term intake of carrots in moderate amounts may have substantial implications in the prevention and treatment of prostate cancer. But Intake of carrot supplements should be taken with care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Dietary carrot consumption and the risk of prostate cancer by Xu X1, Cheng Y, Li S, Zhu Y, Xu X, Zheng X, Mao Q, Xie L(PubMed)
(2) The effect of lycopene on the PI3K/Akt signaling pathway in prostate cancer by Chen J, O'Donoghue A, Deng YF, Zhang B, Kent F, O'Hare T(PubMed)
(3) Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway by Yang CM1, Lu YL, Chen HY, Hu ML(PubMed)
Carrots may have a profound and positive effect in reduced risk, progression, and treatment of prostate cancer, some scientists suggested.
Prostate cancer is a condition characterized by cell growth disorderly and uncontrollably in prostate tissue. At the later stage, the cancerous cells may infect other healthy tissue and organ a distance away from the original site.
Carrot, a root vegetable with orange color is a sub spice of Daucus carota, belongings to the family Apiaceae, native to Asia and Europe.
The study to verify the effect of carrots on the risk of prostate cancer by reviewing the publication of literature in August 2013 of PubMed, EMBASE, Scopus, Web of Science, the Cochrane Register, and the Chinese National Knowledge Infrastructure databases, and the references of the retrieved articles, researchers at the Zhejiang University found that intake of carrot demonstrated a significantly reduced risk of prostate cancer with the odd ratio of .82 in compared to the non-serving group.
The risk of prostate cancer was decreased by 5% and 6% in intake of a weekly portion of 10 g of carrot increment without precipitating adverse effects.
Dr. Xu X, the lead author suggested that the intake of carrots frequently with limited volume may have a profound effect in reducing prostate cancer risk.
Further analysis of the potential effect of lycopene extract found abundantly in tomato and carrot in decreased risk of onset and treatment of prostate cancer indicated that lycopene inhibited prostate cancer proliferation through modulated the expression of PI3K/Akt pathway prostate cancer cell lines in regulating cancerous cellular functions including metabolism, growth, proliferation.
Dysfunction of the PI3K/Akt pathway was associated with a number of human diseases including cancer, diabetes, cardiovascular disease, and neurological diseases.
Moreover, the application of lycopene also displayed a strong effect in inhibiting the proliferation of androgen-dependent prostateLNCaP cancer cells through the activation of the peroxisome proliferator-activated receptor gamma (PPARγ) with the function to act as a tumor suppressor in prostate cells due to its activity in the induction of agonist ligands in inhibited growth of prostate cancer cells.
Additionally, the phytochemical also expressed a significant activity in exhibiting the liver X receptor alpha (LXRα) in reducing the proliferation of human oral cancer cells by promoting cell cycle arrest through increased expression of the cyclin-dependent kinase inhibitor p27, a tumor suppressor and promoted function of extracellular ATP-binding cassette transporter 1 (ABCA1) pathway in inhibited tumor growth through modulation of macrophage function within the tumor, and in establishing a link between cholesterol homeostasis and cancer.
Application of lycopene (10 μM) in the presence of a specific antagonist of PPARγ (GW9662) or LXRα (GGPP) exerted a huge effect in reduced liver X receptor α knockdown in the induction of resistance against LXRα in promoted the proliferation of DU145 cells.
Interestingly, lycopene in combination with the LXRα agonist T0901317, a potent chemical compound used in assays, exhibited anti-prostate cell proliferative activity through interaction with protein expression of PPARγ, LXRα, and ABCA1 in initiated cancer cell apoptosis.
In conclusion, Dr. Yang CM, the lead author said, "These results demonstrate that lycopene can inhibit DU145 cell proliferation via PPARγ-LXRα-ABCA1 pathway and that lycopene and T0901317 exhibit synergistic effects".
The result findings strongly suggested that long-term intake of carrots in moderate amounts may have substantial implications in the prevention and treatment of prostate cancer. But Intake of carrot supplements should be taken with care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Dietary carrot consumption and the risk of prostate cancer by Xu X1, Cheng Y, Li S, Zhu Y, Xu X, Zheng X, Mao Q, Xie L(PubMed)
(2) The effect of lycopene on the PI3K/Akt signaling pathway in prostate cancer by Chen J, O'Donoghue A, Deng YF, Zhang B, Kent F, O'Hare T(PubMed)
(3) Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway by Yang CM1, Lu YL, Chen HY, Hu ML(PubMed)
#Fennel #Extract Shows A Strong #AntipyreticActivity Against #Hyperpyrexia in Vivos. Researchers Say
Kyle J. Norton
Scientists may have found food and plant processes the antipyretic activity comparable to those of acetaminophen in patients with fever, some studies suggested.
Fever is a natural reaction caused by the production of pro-inflammatory cytokines in the immune system in protecting our body from damage and injury against foreign pathogens during the acute phase of infection.
According to medical literature, a person is not considered to have a significant fever until the temperature is above 100.4 F (38.0 C).
Although fever is a common syndrome, however, if you or your kid are experiencing fever accompanied by symptoms of a severe headache, unusual skin rash, sensitivity to bright light, persistent stiff neck and pain, mental confusion, particularly persistent vomiting, and difficulty breathing or chest pain, you or your kid should go to the hospital right the way.
Fennel (Foeniculum vulgare) is a plant species of the genus Foeniculum, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The plant and food have been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the study to evaluate the antipyretic effect of the aqueous extract of an herbal coded formulation containing an equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, in a yeast-induced pyrexia model in rabbits, researchers found that after recording the results immediately before the administration of the extractor paracetamol and again at 1 hour, application of the extract at 240mg/kg dose significant reduces elevated temperature as compared with that of standard drug paracetamol (150mg/kg).
Fennel extract applied alone showed antipyretic activity against hyperpyrexia in mice, induced by S.C. administration of 2 mL/100 g of a 20% aqueous suspension of brewer's yeast.
As an antipyretic agent, ethanolic extract of F. vulgare fruit showed a moderate antipyretic activity that was statistically significant after 30 and 90 min.
These results showed that herbal coded medicine at a dose of 240mg/kg and fennel extract have marked an antipyretic activity in animal models and this was strongly supported by the ethnopharmacological uses of medicinal plants.
Furthermore, in the examine the hepatotoxicity induced by acetaminophen caused by the excessive production of N-acetyl-para-benzoquinone imine (NAPQI) in the induction of symptoms such as fever due to inflammation, researchers showed that the application of trans-anethole, aromatic compounds isolated from fennel exerted a significant effect in the inhibited pro-inflammatory mediators such as prostaglandin (PGE2), cytokines (TNF, IL-1) and nitric oxide (NO)thus decreasing the risk of fever caused by overreaction of the immune system.
Application of AN at doses 125 and 250mg/kg once a day for seven days prevented the changes caused by the APAP overdose.
Additionally, researchers also discovered, AN infection prevents the overexpression of proinflammatory mediators such as NO, TNF, IL-1α, MIP-1α, and MCP-1 and induced the up-regulation of anti-inflammatory cytokines (IL-4 and IL-10), thus reducing the onset of fever.
Taken together, there is no doubt that fennel may be considered a functional food for the treatment of inflammatory-induced fever.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) Antipyretic potential of herbal coded formulation (Pyrexol) by Khan MS1, Hamid A2, Akram M3, Mustafa SB3, Sami A1, Shah SMA4, Usmanghani K(PubMed)
(3) Acetaminophen-induced hepatotoxicity: Preventive effect of trans-anethole by da Rocha BA1, Ritter AM2, Ames FQ3, Gonçalves OH4, Leimann FV5, Bracht L6, Natali MR7, Cuman RK8, Bersani-Amado CA(PubMed)
Scientists may have found food and plant processes the antipyretic activity comparable to those of acetaminophen in patients with fever, some studies suggested.
Fever is a natural reaction caused by the production of pro-inflammatory cytokines in the immune system in protecting our body from damage and injury against foreign pathogens during the acute phase of infection.
According to medical literature, a person is not considered to have a significant fever until the temperature is above 100.4 F (38.0 C).
Although fever is a common syndrome, however, if you or your kid are experiencing fever accompanied by symptoms of a severe headache, unusual skin rash, sensitivity to bright light, persistent stiff neck and pain, mental confusion, particularly persistent vomiting, and difficulty breathing or chest pain, you or your kid should go to the hospital right the way.
Fennel (Foeniculum vulgare) is a plant species of the genus Foeniculum, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The plant and food have been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the study to evaluate the antipyretic effect of the aqueous extract of an herbal coded formulation containing an equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, in a yeast-induced pyrexia model in rabbits, researchers found that after recording the results immediately before the administration of the extractor paracetamol and again at 1 hour, application of the extract at 240mg/kg dose significant reduces elevated temperature as compared with that of standard drug paracetamol (150mg/kg).
Fennel extract applied alone showed antipyretic activity against hyperpyrexia in mice, induced by S.C. administration of 2 mL/100 g of a 20% aqueous suspension of brewer's yeast.
As an antipyretic agent, ethanolic extract of F. vulgare fruit showed a moderate antipyretic activity that was statistically significant after 30 and 90 min.
These results showed that herbal coded medicine at a dose of 240mg/kg and fennel extract have marked an antipyretic activity in animal models and this was strongly supported by the ethnopharmacological uses of medicinal plants.
Furthermore, in the examine the hepatotoxicity induced by acetaminophen caused by the excessive production of N-acetyl-para-benzoquinone imine (NAPQI) in the induction of symptoms such as fever due to inflammation, researchers showed that the application of trans-anethole, aromatic compounds isolated from fennel exerted a significant effect in the inhibited pro-inflammatory mediators such as prostaglandin (PGE2), cytokines (TNF, IL-1) and nitric oxide (NO)thus decreasing the risk of fever caused by overreaction of the immune system.
Application of AN at doses 125 and 250mg/kg once a day for seven days prevented the changes caused by the APAP overdose.
Additionally, researchers also discovered, AN infection prevents the overexpression of proinflammatory mediators such as NO, TNF, IL-1α, MIP-1α, and MCP-1 and induced the up-regulation of anti-inflammatory cytokines (IL-4 and IL-10), thus reducing the onset of fever.
Taken together, there is no doubt that fennel may be considered a functional food for the treatment of inflammatory-induced fever.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) Antipyretic potential of herbal coded formulation (Pyrexol) by Khan MS1, Hamid A2, Akram M3, Mustafa SB3, Sami A1, Shah SMA4, Usmanghani K(PubMed)
(3) Acetaminophen-induced hepatotoxicity: Preventive effect of trans-anethole by da Rocha BA1, Ritter AM2, Ames FQ3, Gonçalves OH4, Leimann FV5, Bracht L6, Natali MR7, Cuman RK8, Bersani-Amado CA(PubMed)
#Herbal #Cinnamon Processes Anti-Infertility Property in Males, Scientists Say
Kyle J. Norton
Scientists may have found a kitchen spice that processes some underline mechanisms in enhancing the rate of fertility, some studies suggested.
Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or the cannot carry the pregnancy full term.
The syndrome affects over 5 million couples alone in the US. Because of the unawareness of treatments, only 10% seek help from professionals.
According to the statistic, about 35% of infertility is caused by the male's inability to fertilize. 35% is caused by the female's inability to conceive, 10% attributes to both, and 10 % is considered a failure with an unknown cause.
Dr, Romero Ramos R, in the study [Risk factors associated to female infertility], wrote, "There were 6 factors with statistical significance: advanced age (p < 0.001), elevated body mass index (p < 0.001), age of onset of sexual activity (p < 0.001), prior pelvic surgeries (p < 0.001), and presence of stress (p < 0.001). Other risk factors such as smoking, chemical, and radiological treatments, pelvic inflammatory disease, exercise, contraceptive use, alcohol intake, drugs, coffee, solvents, glue, and insecticides, were not significant".
In male infertility, according to a case-control study conducted by Dr. Buiatti E and colleagues, about coffee and alcohol consumption, smoking habits, x-ray exposure, usual sitting posture, drug consumption, other nonoccupational risk factors, socioeconomic status, education level, and occupational history are some of the prevalent risk factors associated to male infertility.
And, the high relative risk was associated with (a) occupation in the radioelectric industry, (b) non sedentary clerical workers, (c) clerical work in the typographic industry, and (d) occupation in the textile industry,
Cinnamon, a kitchen spice in many cultures, may be best known for its effectiveness in reducing the levels of blood glucose in diabetics and lipid peroxidation through its antioxidant activity(4).
In a total of 45 women with Polycystic Ovary Syndrome, randomized, 26 women completed 3 months of the study, and 17 women completed the entire 6 months of the study, researchers showed,
* Application of cinnamon exerts a positive effect in the improvement of menstrual cyclicity associated with luteal phase progesterone levels and ovulatory menses without altering insulin resistance or serum androgen levels
* Cinnamaldehyde, a major chemical compound of cinnamon enhances fertility through selectively induced progesterone production and inhibits the production of testosterone and dehydroepiandrosterone in human adrenal cells.
* Further differentiation, suggested that cinnamon extract not only reduces insulin resistance in vitro and in vivo by increasing phosphatidylinositol 3-kinase activity with insulin stimulation in the insulin signaling pathway but also improves menstrual cyclicity in female-induced PCOs.
Moreover, in the infertile male rat study conducted by Fırat University, long-term cinnamon bark oil(CPO) improved the effect on testicular oxidant-antioxidant balance and sperm quality by significantly decreasing the abnormal sperm rate and apoptotic germ cell count.
Interestingly, in the study to investigate the likelihood of detrimental effects of carbon tetrachloride (CCl4 ) on the male reproductive system through oxidative stress mechanism and also the protective effects of cinnamon bark oil (CBO), researchers at the Firat University conducted an experiment including 28 healthy male Wistar rats.
The tested subjects were divided into four groups, seven rats in each. Group 1 received only olive oil daily; group 2 was treated with 100 mg kg(-1) CBO daily; group 3 was treated with only 0.25 ml kg(-1) CCl4 weekly, and group 4 received weekly CCl4 + daily CBO.
All administrations were made by the intragastric catheter and maintained for 10 weeks.
In the final report, researchers suggested that
* CCl4 administration caused significant decreases in body and reproductive organ weights, testicular catalase (CAT) activity, sperm motility and concentration, and significant increases in lipid peroxidation (LPO) level, abnormal sperm rate, and apoptotic index along with some histopathological damages compared with the control group.
* Pretreatment of CBO following the administration of CCl4 significant improvements in absolute weights of testis and epididymis, all sperm quality parameters, LPO level, apoptotic index, and testicular histopathological structure Cl4, compared to the group given CCl4 only.
Taken together, Cinnamon may be effective in promoting fertility in both sexes through enhancing the menstrual cycle in women and improving sperm performance in men.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Preliminary Evidence that Cinnamon Improves Menstrual Cyclicity in Women with Polycystic Ovarian Syndrome: a Randomized Controlled Trial by Kort DH1, Lobo RA. (PubMed)
(2) Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell, and sperm quality by Yüce A1, Türk G, Çeribaşi S, Sönmez M, Çiftçi M, Güvenç M.(PubMed)
(3) Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells by Iwaoka Y1, Hashimoto R, Koizumi H, Yu J, Okabe T.(PubMed)
(4) Preventive effect of cinnamon essential oil on lipid oxidation of vegetable oil by Keshvari M1, Asgary S, Jafarian-Dehkordi A, Najafi S, Ghoreyshi-Yazdi SM(PubMed)
(5) Popular #Herbs - #Dang Qui (Angelica Sinensis)
(6) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA.(PubMed)
(7) Effectiveness of cinnamon (Cinnamomum zeylanicum) bark oil in the prevention of carbon tetrachloride-induced damages on the male reproductive system by Yüce A1, Türk G, Çeribaşı S, Güvenç M, Çiftçi M, Sönmez M, Özer Kaya Ş, Çay M, Aksakal M.(PubMed)
(8) The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study by Wang JG1, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, Lobo RA. (PubMed)
(8) [Risk factors associated to female infertility].[Article in Spanish] by Romero Ramos R1, Romero Gutiérrez G, Abortes Monroy I, Medina Sánchez HG. (PubMed)
Scientists may have found a kitchen spice that processes some underline mechanisms in enhancing the rate of fertility, some studies suggested.
Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or the cannot carry the pregnancy full term.
The syndrome affects over 5 million couples alone in the US. Because of the unawareness of treatments, only 10% seek help from professionals.
According to the statistic, about 35% of infertility is caused by the male's inability to fertilize. 35% is caused by the female's inability to conceive, 10% attributes to both, and 10 % is considered a failure with an unknown cause.
Dr, Romero Ramos R, in the study [Risk factors associated to female infertility], wrote, "There were 6 factors with statistical significance: advanced age (p < 0.001), elevated body mass index (p < 0.001), age of onset of sexual activity (p < 0.001), prior pelvic surgeries (p < 0.001), and presence of stress (p < 0.001). Other risk factors such as smoking, chemical, and radiological treatments, pelvic inflammatory disease, exercise, contraceptive use, alcohol intake, drugs, coffee, solvents, glue, and insecticides, were not significant".
In male infertility, according to a case-control study conducted by Dr. Buiatti E and colleagues, about coffee and alcohol consumption, smoking habits, x-ray exposure, usual sitting posture, drug consumption, other nonoccupational risk factors, socioeconomic status, education level, and occupational history are some of the prevalent risk factors associated to male infertility.
And, the high relative risk was associated with (a) occupation in the radioelectric industry, (b) non sedentary clerical workers, (c) clerical work in the typographic industry, and (d) occupation in the textile industry,
Cinnamon, a kitchen spice in many cultures, may be best known for its effectiveness in reducing the levels of blood glucose in diabetics and lipid peroxidation through its antioxidant activity(4).
In a total of 45 women with Polycystic Ovary Syndrome, randomized, 26 women completed 3 months of the study, and 17 women completed the entire 6 months of the study, researchers showed,
* Application of cinnamon exerts a positive effect in the improvement of menstrual cyclicity associated with luteal phase progesterone levels and ovulatory menses without altering insulin resistance or serum androgen levels
* Cinnamaldehyde, a major chemical compound of cinnamon enhances fertility through selectively induced progesterone production and inhibits the production of testosterone and dehydroepiandrosterone in human adrenal cells.
* Further differentiation, suggested that cinnamon extract not only reduces insulin resistance in vitro and in vivo by increasing phosphatidylinositol 3-kinase activity with insulin stimulation in the insulin signaling pathway but also improves menstrual cyclicity in female-induced PCOs.
Moreover, in the infertile male rat study conducted by Fırat University, long-term cinnamon bark oil(CPO) improved the effect on testicular oxidant-antioxidant balance and sperm quality by significantly decreasing the abnormal sperm rate and apoptotic germ cell count.
Interestingly, in the study to investigate the likelihood of detrimental effects of carbon tetrachloride (CCl4 ) on the male reproductive system through oxidative stress mechanism and also the protective effects of cinnamon bark oil (CBO), researchers at the Firat University conducted an experiment including 28 healthy male Wistar rats.
The tested subjects were divided into four groups, seven rats in each. Group 1 received only olive oil daily; group 2 was treated with 100 mg kg(-1) CBO daily; group 3 was treated with only 0.25 ml kg(-1) CCl4 weekly, and group 4 received weekly CCl4 + daily CBO.
All administrations were made by the intragastric catheter and maintained for 10 weeks.
In the final report, researchers suggested that
* CCl4 administration caused significant decreases in body and reproductive organ weights, testicular catalase (CAT) activity, sperm motility and concentration, and significant increases in lipid peroxidation (LPO) level, abnormal sperm rate, and apoptotic index along with some histopathological damages compared with the control group.
* Pretreatment of CBO following the administration of CCl4 significant improvements in absolute weights of testis and epididymis, all sperm quality parameters, LPO level, apoptotic index, and testicular histopathological structure Cl4, compared to the group given CCl4 only.
Taken together, Cinnamon may be effective in promoting fertility in both sexes through enhancing the menstrual cycle in women and improving sperm performance in men.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Preliminary Evidence that Cinnamon Improves Menstrual Cyclicity in Women with Polycystic Ovarian Syndrome: a Randomized Controlled Trial by Kort DH1, Lobo RA. (PubMed)
(2) Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell, and sperm quality by Yüce A1, Türk G, Çeribaşi S, Sönmez M, Çiftçi M, Güvenç M.(PubMed)
(3) Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells by Iwaoka Y1, Hashimoto R, Koizumi H, Yu J, Okabe T.(PubMed)
(4) Preventive effect of cinnamon essential oil on lipid oxidation of vegetable oil by Keshvari M1, Asgary S, Jafarian-Dehkordi A, Najafi S, Ghoreyshi-Yazdi SM(PubMed)
(5) Popular #Herbs - #Dang Qui (Angelica Sinensis)
(6) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA.(PubMed)
(7) Effectiveness of cinnamon (Cinnamomum zeylanicum) bark oil in the prevention of carbon tetrachloride-induced damages on the male reproductive system by Yüce A1, Türk G, Çeribaşı S, Güvenç M, Çiftçi M, Sönmez M, Özer Kaya Ş, Çay M, Aksakal M.(PubMed)
(8) The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study by Wang JG1, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, Lobo RA. (PubMed)
(8) [Risk factors associated to female infertility].[Article in Spanish] by Romero Ramos R1, Romero Gutiérrez G, Abortes Monroy I, Medina Sánchez HG. (PubMed)
#Herbal #Anise Exhibits Anti Microbial Activities by Modulating the Immune Response, Scientists Find
Kyle J. Norton
Herbal Anise may have a synergistic antibacterial activity effect in reduced risk and treatment of infection, some scientists suggested.
Bacteria are microorganism consisted of consist of a single cell with a simple internal structure. harmless. most of them are harmless to humans and can be distinguished by the nature of their cell walls, their shape, or by differences in their genetic makeup.
Bacteria reproduced through cell cycle division. in other words, they multiply by making a copy of the DNA and grow large in size by doubling its cellular content. before splitting it into two identical "daughter" cells.
Bacteria can also be beneficial to human health as they help to maintain the orderly functioning of the digestive system such as digesting food that the stomach can not digest, producing the vitamins for our body needs, improving the immune function and most importantly, ensuring the optimal digestive functioning.
Some infectious bacteria are dangerous to human health. As they can divide quickly, after entering the body. Many produce chemicals called toxins, which not only fence off the attack from immune system but also can damage.
Due to antibiotics overuse over large 3 decades, some infected bacteria have developed antibiotic resistance, a phenomenon where infectious bacteria are no longer susceptible to previously effective antibiotics.
Synergistic antibacterial activity is a condition in which whole herb application exerts a greater effect than the sum of individual ingredients combined.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners, and stomachic, antiseptic, anti-spasmodic,...
In the comparison of the antibacterial effect against a wide range of foodborne Gram-positive and -negative bacteria, yeasts, and molds by an agar well diffusion method in five different varieties of Ocimum basilicum L. plants, including Anise, researchers found that application of Anise essential oil exhibited a strong effect in decreased expression the acid-tolerant microorganisms including Lactobacillus curvatus and Saccharomyces cerevisiae, synergistically, compared to mixtures of the predominant components of pure linalool and methyl chavicol.
In a tomato juice medium, Anise oil injection also exerted antibacterial activity at doses of 0·1% and 1% Anise oil, against Lact. curvatus and S. cerevisiae, respectively.
The inhibitory effect of Anise oil was substantially higher, in comparison to the mixtures of the predominant components of pure linalool and methyl chavicol, against the acid-tolerant organisms, Lactobacillus curvatus and Saccharomyces cerevisiae, examined in broth by an indirect impedance method.
Furthermore, essential oil extracted from the Anise seed used alone or combined with essential oil extracted from from aerial parts of Thymus vulgaris, also displayed a significant effect in inhibiting nine Gram-positive and Gram-negative pathogenic bacteria: Staphylococcus aureus, Bacillus cereus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Salmonella typhi, Salmonella typhimurium, Klebsiella pneumoniae and Pseudomonas aeruginosa.
Pimpinella anisum essential oils methanol extracts at doses of MIC 15.6 and 62.5mug/ml) were particularly effective against Staphylococcus aureus, Bacillus cereus, and Proteus vulgaris.
Some researchers suggested that Anise's antibacterial effect probably was attributed to the bioactive major compound anethole in the modulation of immunity.
According to some studies, the application of essential oil in mice model, trans-anethole and estragole, a derivative of anethole improved the host immunity by reducing the expression of hypersensitivity response and increasing the numbers of white blood cells(leucocytes) in the circulatory system with function in counteracting foreign substances and diseases.
Further differentiation also found that trans-anethole improved the immune function in stimulating the transformation of B cells into plasma cells in the produced and secreted antibodies whether a foreign substance was scented.
Additionally, anethole isolated from Anise also exhibited a strong effect in protecting the immunity against mice fed with cyclophosphamide to induced chemo suppression of immunity.
Indeed, an Anise essential oil demonstrated a significant effect in the immune responses by modulating the levels of immune-inflammatory factors interleukins (IL6, IL8, and IL10) and tumor necrosis factor(TNFα ) against infectious microorganism in initiating the acute phase of infection.
Additionally, in animal tested with E. acervulina-infected, application of essential oil isolated from Anise also increased expression of lymphocytes in the infectious intestinal area.
Taken together, the findings suggested that Anise essential oil including the bioactive phytochemical anethole may be used as an antibacterial agent, particularly in the externally acute phase of infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The synergistic preservative effects of the essential oils of sweet basil (Ocimum basilicum L.) against acid-tolerant food microflora K.J. Lachowicz1 , G.P. Jones1 , D.R. Briggs1 , F.E. Bienvenu2 , J. Wan3 , A. Wilcock3 and M.J. Coventry3 1School of Nutrition and Public Health, Deakin University, Geelong, 2Ovens Research Station, Department of Natural Resources and Environment, Myrtleford, and 3Australian Food Industry Science Centre, Werribee, Victoria, Australia(Letters in Applied Microbiology Volume 26, Issue 3, Version of Record online: 4 JAN 2002)
(2) Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts by Al-Bayati FA1.(PubMed)
(3) Evaluation of immunomodulatory activity of trans-anethole and estragole, and protective effect against cyclophosphamide-induced suppression of immunity in Swiss albino mice by Luiz Alexandre Marques Wiirzler, Francielli Maria de Souza Silva-Comar, Saulo Euclides Silva-Filho, Michael Jefferson Amorim de Oliveira, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman(International Journal of Applied Research in Natural Products)
(4) Immune effects of dietary anethole on Eimeria acervulina infection by Kim DK1, Lillehoj HS, Lee SH, Jang SI, Park MS, Min W, Lillehoj EP, Bravo D.(PubMed)
Herbal Anise may have a synergistic antibacterial activity effect in reduced risk and treatment of infection, some scientists suggested.
Bacteria are microorganism consisted of consist of a single cell with a simple internal structure. harmless. most of them are harmless to humans and can be distinguished by the nature of their cell walls, their shape, or by differences in their genetic makeup.
Bacteria reproduced through cell cycle division. in other words, they multiply by making a copy of the DNA and grow large in size by doubling its cellular content. before splitting it into two identical "daughter" cells.
Bacteria can also be beneficial to human health as they help to maintain the orderly functioning of the digestive system such as digesting food that the stomach can not digest, producing the vitamins for our body needs, improving the immune function and most importantly, ensuring the optimal digestive functioning.
Some infectious bacteria are dangerous to human health. As they can divide quickly, after entering the body. Many produce chemicals called toxins, which not only fence off the attack from immune system but also can damage.
Due to antibiotics overuse over large 3 decades, some infected bacteria have developed antibiotic resistance, a phenomenon where infectious bacteria are no longer susceptible to previously effective antibiotics.
Synergistic antibacterial activity is a condition in which whole herb application exerts a greater effect than the sum of individual ingredients combined.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners, and stomachic, antiseptic, anti-spasmodic,...
In the comparison of the antibacterial effect against a wide range of foodborne Gram-positive and -negative bacteria, yeasts, and molds by an agar well diffusion method in five different varieties of Ocimum basilicum L. plants, including Anise, researchers found that application of Anise essential oil exhibited a strong effect in decreased expression the acid-tolerant microorganisms including Lactobacillus curvatus and Saccharomyces cerevisiae, synergistically, compared to mixtures of the predominant components of pure linalool and methyl chavicol.
In a tomato juice medium, Anise oil injection also exerted antibacterial activity at doses of 0·1% and 1% Anise oil, against Lact. curvatus and S. cerevisiae, respectively.
The inhibitory effect of Anise oil was substantially higher, in comparison to the mixtures of the predominant components of pure linalool and methyl chavicol, against the acid-tolerant organisms, Lactobacillus curvatus and Saccharomyces cerevisiae, examined in broth by an indirect impedance method.
Furthermore, essential oil extracted from the Anise seed used alone or combined with essential oil extracted from from aerial parts of Thymus vulgaris, also displayed a significant effect in inhibiting nine Gram-positive and Gram-negative pathogenic bacteria: Staphylococcus aureus, Bacillus cereus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Salmonella typhi, Salmonella typhimurium, Klebsiella pneumoniae and Pseudomonas aeruginosa.
Pimpinella anisum essential oils methanol extracts at doses of MIC 15.6 and 62.5mug/ml) were particularly effective against Staphylococcus aureus, Bacillus cereus, and Proteus vulgaris.
Some researchers suggested that Anise's antibacterial effect probably was attributed to the bioactive major compound anethole in the modulation of immunity.
According to some studies, the application of essential oil in mice model, trans-anethole and estragole, a derivative of anethole improved the host immunity by reducing the expression of hypersensitivity response and increasing the numbers of white blood cells(leucocytes) in the circulatory system with function in counteracting foreign substances and diseases.
Further differentiation also found that trans-anethole improved the immune function in stimulating the transformation of B cells into plasma cells in the produced and secreted antibodies whether a foreign substance was scented.
Additionally, anethole isolated from Anise also exhibited a strong effect in protecting the immunity against mice fed with cyclophosphamide to induced chemo suppression of immunity.
Indeed, an Anise essential oil demonstrated a significant effect in the immune responses by modulating the levels of immune-inflammatory factors interleukins (IL6, IL8, and IL10) and tumor necrosis factor(TNFα ) against infectious microorganism in initiating the acute phase of infection.
Additionally, in animal tested with E. acervulina-infected, application of essential oil isolated from Anise also increased expression of lymphocytes in the infectious intestinal area.
Taken together, the findings suggested that Anise essential oil including the bioactive phytochemical anethole may be used as an antibacterial agent, particularly in the externally acute phase of infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The synergistic preservative effects of the essential oils of sweet basil (Ocimum basilicum L.) against acid-tolerant food microflora K.J. Lachowicz1 , G.P. Jones1 , D.R. Briggs1 , F.E. Bienvenu2 , J. Wan3 , A. Wilcock3 and M.J. Coventry3 1School of Nutrition and Public Health, Deakin University, Geelong, 2Ovens Research Station, Department of Natural Resources and Environment, Myrtleford, and 3Australian Food Industry Science Centre, Werribee, Victoria, Australia(Letters in Applied Microbiology Volume 26, Issue 3, Version of Record online: 4 JAN 2002)
(2) Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts by Al-Bayati FA1.(PubMed)
(3) Evaluation of immunomodulatory activity of trans-anethole and estragole, and protective effect against cyclophosphamide-induced suppression of immunity in Swiss albino mice by Luiz Alexandre Marques Wiirzler, Francielli Maria de Souza Silva-Comar, Saulo Euclides Silva-Filho, Michael Jefferson Amorim de Oliveira, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman(International Journal of Applied Research in Natural Products)
(4) Immune effects of dietary anethole on Eimeria acervulina infection by Kim DK1, Lillehoj HS, Lee SH, Jang SI, Park MS, Min W, Lillehoj EP, Bravo D.(PubMed)
#Greentea's Theanine Inhibits the Onset of #Manic and #Depressive #Episodes in #BipolarDisorder, Researchers Find
Kyle J. Norton
Green tea's major bioactive theanine may have a potential and positive effect in blocking the onset of bipolar disorder, some scientists suggested.
Bipolar disorder is a condition of brain disorder characterized by unusual shifting mood, energy, activity levels, and interfering the brain function in carrying out day-to-day tasks.
According to the National Institute of Mental Health, the conditions can be classified in to
* Bipolar I disorder with severe manic episodes last at least 7 days, most people with bipolar I disorder needs immediate hospital care.
* Bipolar II disorder is characterized by a pattern of depressive episodes and hypomanic episodes.
* Cyclothymic disorder also known as cyclothymia is a condition with numerous periods of hypomanic and depressive symptoms that lasting for at least 2 years.
*4. Other conditions that do not match the 3 above.
Dr. Steve Bressert, Ph.D. in the article Manic Episode Symptoms, wrote, "The symptoms of mania include: elevated mood, inflated self-esteem, decreased need for sleep, racing thoughts, difficulty maintaining attention, increase in goal-directed activity, and excessive involvement in pleasurable activities" compared to a depressive episode that characterizes with low mood and other depression symptoms that lasts for 2 weeks or more. In some cases, a depressive episode may last several weeks or months at a time.
Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.
In the investigation to determine whether theanine (n-ethylglutamic acid), a non-proteinaceous amino acid component of green and black teas has any protective effects on the central nervous system, researchers found that
* Theanine exerts a variety of neurophysiological and pharmacological effects through crosses the blood-brain barrier.
* Application of theanine also demonstrates the anxiolytic and calming effect by up-regulation of inhibitory neurotransmitters and possible modulation of serotonin and dopamine in selected areas and increasing levels of the brain-derived neurotrophic factor.
* The bioactive compound also displays a neuroprotective effect following cerebral infarct and injury,
* Theanine also elicits improvements in cognitive function including learning and memory,
* Interestingly, theanine administration elicits selective changes in alpha brain wave activity with concomitant increases in selective attention during the execution of mental tasks and inhibits depression.
These results suggested that theanine can be considered a therapeutic role in the treatment of some psychiatric disorders such as anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), and bipolar disorder.
Additionally, in a study by Portland VA Medical Center of adults with schizophrenia, schizoaffective disorder or bipolar disorder who were maintained on antipsychotic and other psychotropic medications randomized to supplemental EGCG or placebo including a total of 34 participants (17 EGCG, 17 placebo) and 25 participants (14 EGCG, 11 placebo), researchers showed that
* Both treatment groups showed significant reductions in psychotic, depressive, and anxiety symptoms from baseline to end of treatment.
* However, EGCG did not significantly affect psychiatric symptoms or inflammatory markers, as compared with placebo.
* Adverse effects were mild and comparable between groups.
The finding indicated that green tea extract EGCG exerts an insignificant effect on psychiatric symptoms in patients with bipolar disorder compared to Theanine, another major ingredient in green and black tea.
Taken together, green and black tea major bioactive theanine may be considered a secondary therapy in protecting the brain against manic and depressive episode in patients with bipolar disorder.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of epigallocatechin gallate supplementation in schizophrenia and bipolar disorder: an 8-week, randomized, double-blind, placebo-controlled study by Loftis JM1, Wilhelm CJ, Huckans M.(PubMed)
(2) Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders by Lardner AL. (PubMed)
Green tea's major bioactive theanine may have a potential and positive effect in blocking the onset of bipolar disorder, some scientists suggested.
Bipolar disorder is a condition of brain disorder characterized by unusual shifting mood, energy, activity levels, and interfering the brain function in carrying out day-to-day tasks.
According to the National Institute of Mental Health, the conditions can be classified in to
* Bipolar I disorder with severe manic episodes last at least 7 days, most people with bipolar I disorder needs immediate hospital care.
* Bipolar II disorder is characterized by a pattern of depressive episodes and hypomanic episodes.
* Cyclothymic disorder also known as cyclothymia is a condition with numerous periods of hypomanic and depressive symptoms that lasting for at least 2 years.
*4. Other conditions that do not match the 3 above.
Dr. Steve Bressert, Ph.D. in the article Manic Episode Symptoms, wrote, "The symptoms of mania include: elevated mood, inflated self-esteem, decreased need for sleep, racing thoughts, difficulty maintaining attention, increase in goal-directed activity, and excessive involvement in pleasurable activities" compared to a depressive episode that characterizes with low mood and other depression symptoms that lasts for 2 weeks or more. In some cases, a depressive episode may last several weeks or months at a time.
Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.
In the investigation to determine whether theanine (n-ethylglutamic acid), a non-proteinaceous amino acid component of green and black teas has any protective effects on the central nervous system, researchers found that
* Theanine exerts a variety of neurophysiological and pharmacological effects through crosses the blood-brain barrier.
* Application of theanine also demonstrates the anxiolytic and calming effect by up-regulation of inhibitory neurotransmitters and possible modulation of serotonin and dopamine in selected areas and increasing levels of the brain-derived neurotrophic factor.
* The bioactive compound also displays a neuroprotective effect following cerebral infarct and injury,
* Theanine also elicits improvements in cognitive function including learning and memory,
* Interestingly, theanine administration elicits selective changes in alpha brain wave activity with concomitant increases in selective attention during the execution of mental tasks and inhibits depression.
These results suggested that theanine can be considered a therapeutic role in the treatment of some psychiatric disorders such as anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), and bipolar disorder.
Additionally, in a study by Portland VA Medical Center of adults with schizophrenia, schizoaffective disorder or bipolar disorder who were maintained on antipsychotic and other psychotropic medications randomized to supplemental EGCG or placebo including a total of 34 participants (17 EGCG, 17 placebo) and 25 participants (14 EGCG, 11 placebo), researchers showed that
* Both treatment groups showed significant reductions in psychotic, depressive, and anxiety symptoms from baseline to end of treatment.
* However, EGCG did not significantly affect psychiatric symptoms or inflammatory markers, as compared with placebo.
* Adverse effects were mild and comparable between groups.
The finding indicated that green tea extract EGCG exerts an insignificant effect on psychiatric symptoms in patients with bipolar disorder compared to Theanine, another major ingredient in green and black tea.
Taken together, green and black tea major bioactive theanine may be considered a secondary therapy in protecting the brain against manic and depressive episode in patients with bipolar disorder.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of epigallocatechin gallate supplementation in schizophrenia and bipolar disorder: an 8-week, randomized, double-blind, placebo-controlled study by Loftis JM1, Wilhelm CJ, Huckans M.(PubMed)
(2) Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders by Lardner AL. (PubMed)
#GreenTea's #EGCG Shows Multifunctional Therapeutic Effects on #AmyotrophicLateralSclerosis in Vivos, Researchers Say
Kyle J. Norton
Green tea may have a therapeutic and positive effect in reduced risk, progression, and treatment of amyotrophic lateral sclerosis (ALS), some scientists suggested.
Green tea is a precious drink that processed a number of health benefits and is known to almost everyone in Asia and the Western world.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a specific disease that involved the death of neurons in controlling voluntary muscles.
According to the research published by Hanyang University, the administration of green tea Epigallocatechin gallate (EGCG) exerted a neuroprotective effect in reduced oxidative stress in orchestrated death of neurons.
In the evaluation of green tea EGCG in risk of amyotrophic lateral sclerosis (ALS) in human G93A(with function is responsible for destroying free superoxide radicals in the body) mutated Cu/Zn-superoxide dismutase (SOD1) gene in mice model, scientists found that
application of green tea EGCG at doses of 1.5, 2.9, and 5.8 microg/g body weight, dissolved in 0.5 ml of 0.9% sterile NaCl intraorally every day after 60 days of age demonstrate significant effects in prolonged symptom onset and life span of ALS mice through preserved more survival and attenuated death signals.
The result of the increased life span of mutated gene mice was attributed to the increased antioxidant activity of green tea in inhibiting the levels of ROS in reduced cytotoxicity in initiated death of neurons in controlling voluntary muscles.
Further analysis of the effect of green tea in mutated SOD1-G93A in transgenic mice and wild-type mice randomly divided into EGCG-treated groups (10 mg/kg, p.o) and vehicle-treated control groups to assess the motor function, starting at the age of 70 days researchers found that injection of green tea treatment mice displays a strong effect in delayed the onset of disease, and extended life span, similar to those in the Hanyang study.
Additional differentiation also indicated that the green tea treatment group stimulated the production of a number of new motor neurons compared to control mice,
Interestingly, the application also decreased the over-expression of microglial activation in initiating the inflammatory response due to neuronal damage and removed the damaged cells caused by phagocytosis production.
Prolonged and over-expression of inflammatory cytokines may increase the risk of neuron damage and in some cases death of the nerve cells.
In in-depth analysis showed that green tea reduced the immunohistochemical reaction of NF-kappaB in response to the neuron damage (by antigens) through stimulated production of pro-inflammatory factors (as an antibody) and cleaved caspase-3 in the induction of neuron apoptosis.
Moreover, the application of green EGCG also expressed a similar result as in other studies in the decreased protein level of iNOS and NF-kappaB in the spinal cords in orchestrated free radical NO levels and inflammatory cytokines in neuron cell death in the spinal cord involving the onset of ALS.
Dr. Xu Z, the lead author after taking into account other co-founders said, "This study provides further evidence that EGCG has multifunctional therapeutic effects in the mouse model of ALS".
These results were supported by the study of the green tea effect on the risk of Lou Gehrig's disease by reviewing the food selection of a 44-item food frequency questionnaire of 1 million men and women enrolled and conducted in 1989 through 2002 for ALS mortality.
According to the results of the study, researchers at the Harvard School of Public Health suggested that green tea injection is associated with a reduced mortality rate of patients.
The information findings suggested that green tea and its bioactive polyphenol Epigallocatechin gallate (EGCG) may be considered as a functional food for reduced risk and used in combination with standard medicine in delayed progression and treatment of Amyotrophic lateral sclerosis (ALS).
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Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Diet and amyotrophic lateral sclerosis by Morozova N1, Weisskopf MG, McCullough ML, Munger KL, Calle EE, Thun MJ, Ascherio A.(PubMed)
(2) Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis by Xu Z1, Chen S, Li X, Luo G, Li L, Le W.(PubMed)
(3) The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice by Koh SH1, Lee SM, Kim HY, Lee KY, Lee YJ, Kim HT, Kim J, Kim MH, Hwang MS, Song C, Yang KW, Lee KW, Kim SH, Kim OH. (PubMed)
Green tea may have a therapeutic and positive effect in reduced risk, progression, and treatment of amyotrophic lateral sclerosis (ALS), some scientists suggested.
Green tea is a precious drink that processed a number of health benefits and is known to almost everyone in Asia and the Western world.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a specific disease that involved the death of neurons in controlling voluntary muscles.
According to the research published by Hanyang University, the administration of green tea Epigallocatechin gallate (EGCG) exerted a neuroprotective effect in reduced oxidative stress in orchestrated death of neurons.
In the evaluation of green tea EGCG in risk of amyotrophic lateral sclerosis (ALS) in human G93A(with function is responsible for destroying free superoxide radicals in the body) mutated Cu/Zn-superoxide dismutase (SOD1) gene in mice model, scientists found that
application of green tea EGCG at doses of 1.5, 2.9, and 5.8 microg/g body weight, dissolved in 0.5 ml of 0.9% sterile NaCl intraorally every day after 60 days of age demonstrate significant effects in prolonged symptom onset and life span of ALS mice through preserved more survival and attenuated death signals.
The result of the increased life span of mutated gene mice was attributed to the increased antioxidant activity of green tea in inhibiting the levels of ROS in reduced cytotoxicity in initiated death of neurons in controlling voluntary muscles.
Further analysis of the effect of green tea in mutated SOD1-G93A in transgenic mice and wild-type mice randomly divided into EGCG-treated groups (10 mg/kg, p.o) and vehicle-treated control groups to assess the motor function, starting at the age of 70 days researchers found that injection of green tea treatment mice displays a strong effect in delayed the onset of disease, and extended life span, similar to those in the Hanyang study.
Additional differentiation also indicated that the green tea treatment group stimulated the production of a number of new motor neurons compared to control mice,
Interestingly, the application also decreased the over-expression of microglial activation in initiating the inflammatory response due to neuronal damage and removed the damaged cells caused by phagocytosis production.
Prolonged and over-expression of inflammatory cytokines may increase the risk of neuron damage and in some cases death of the nerve cells.
In in-depth analysis showed that green tea reduced the immunohistochemical reaction of NF-kappaB in response to the neuron damage (by antigens) through stimulated production of pro-inflammatory factors (as an antibody) and cleaved caspase-3 in the induction of neuron apoptosis.
Moreover, the application of green EGCG also expressed a similar result as in other studies in the decreased protein level of iNOS and NF-kappaB in the spinal cords in orchestrated free radical NO levels and inflammatory cytokines in neuron cell death in the spinal cord involving the onset of ALS.
Dr. Xu Z, the lead author after taking into account other co-founders said, "This study provides further evidence that EGCG has multifunctional therapeutic effects in the mouse model of ALS".
These results were supported by the study of the green tea effect on the risk of Lou Gehrig's disease by reviewing the food selection of a 44-item food frequency questionnaire of 1 million men and women enrolled and conducted in 1989 through 2002 for ALS mortality.
According to the results of the study, researchers at the Harvard School of Public Health suggested that green tea injection is associated with a reduced mortality rate of patients.
The information findings suggested that green tea and its bioactive polyphenol Epigallocatechin gallate (EGCG) may be considered as a functional food for reduced risk and used in combination with standard medicine in delayed progression and treatment of Amyotrophic lateral sclerosis (ALS).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Diet and amyotrophic lateral sclerosis by Morozova N1, Weisskopf MG, McCullough ML, Munger KL, Calle EE, Thun MJ, Ascherio A.(PubMed)
(2) Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis by Xu Z1, Chen S, Li X, Luo G, Li L, Le W.(PubMed)
(3) The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice by Koh SH1, Lee SM, Kim HY, Lee KY, Lee YJ, Kim HT, Kim J, Kim MH, Hwang MS, Song C, Yang KW, Lee KW, Kim SH, Kim OH. (PubMed)
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