Monday, 12 June 2023

#healthyfood #Greentea and its #EGCG Inhibit the Overexpression of #OxidativeStress That Causes #Fibromyalgia, Researchers Suggest

By Kyle J. Norton


Green tea may have a therapeutic and positive effect in reduced risk, progression, and treatment of
fibromyalgia caused by oxidative stress, some scientists suggested.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.

Fibromyalgia (FM) is a chronic condition characterized by muscle and soft tissue pain affecting over 10 million (3.6% of the population) people in the US alone.

According to the study in the review of literature on the frequency and pattern of complementary and alternative medicine (CAM) of 289(95%) patients who completed the survey (263 women and 26 men) between February 2003 and July 2003, green tea was recommended at 24% for treatment of fibromyalgia (FM).

In other words, in herbal medicine, green tea is considered to have a certain effect in reducing the symptoms and treatment for such a syndrome.


Some evidence in medical literature suggested that the overproduction of ROS in the induction of oxidative stress may have a strong implication in the pathophysiology of FM.

In the investigation of the effect of green tea epigallocatechin-3-gallate (EGCG) in the protection of oxidative stress to cardiac cells cultured in the conditions of control, 400 μM H2O2 exposure for 30 min with and/or without 10 to 20 μM EGCG pre-treatment, researchers at the National Tsing Hua University found that treatment of green tea in H(2)O(2) group demonstrated a significant reduction of levels of reactive oxygen species through its antioxidant and its ability in induced production of natural antioxidant present in the cardiac cells in compared to overexpression of ROS in H2O2 treatment group without injection of EGCG.

Also, the application of green tea reduced levels of cytosolic Ca2+ overload in the H(2)O(2) group in induced oxidative stress in experiment cell apoptosis through improved antioxidant protein.

Interestingly, EGCG inhibited the ameliorated H(2)O(2) expression in increased glycolytic protein in response to the degree of oxidative stress in the cultured cells and α-enolase, a key glycolytic enzyme on the surface of several cell types in the contribution of impaired glycolytic activity through oxidative and nitrative stress.

Additionally, green tea EGCG also decreased levels of peroxiredoxin-4, an antioxidant with function in protection against oxidative stress by detoxifying peroxides and mitochondrial proteins with the function of redox reactions of oxidative phosphorylation.

After taking into account other confounders, researchers suggested that ingestion of green tea EGCG inhibited the damage of the H(2)O(2) group through inhibition of the downstream signaling for Akt in expression glucose oxidation and cell apoptosis in cellular processes and loss of phosphorylation of GSK-3β and cyclin D1 depletion in facilitated oxidative stress.

These results postulated that green tea EGCG exerted a similar inhibited effect of those of GSK-3β inhibitor (SB 216763) in significantly improved H(2)O(2)-induced suppression on cell viability, phosphorylation of pAkt (S473) and pGSK-3β (S9), and level of cyclin D1 in cells.


The above differentiation was supported by the study conducted by the Universidad de Sevilla, in evaluating some evidence of green tea in reduced oxidative stress in facilitated pathophysiology of FM in initiated signs and symptoms of muscular alteration and mitochondrial dysfunction.

Truly, in the primary rat model, administration of green tea EGCG in different concentrations for 24 h before being exposed to hydrogen peroxide (H(2)O(2)) for 2 h to induce oxidative stress, researchers found that pretreatment with 10, 25, and 50 µM EGCG significantly inhibited the expression of H2O2 in a reduced substantial decrease in cell viability.

Further analysis also showed that green tea EGCG application dose of 50 µM ameliorated the proportion of propidium iodide (PI)-positive cells increased in cultures caused by H(2)O(2) injection, thus reducing H(2)O(2) in induced cell death.

Taken together, green tea and its bioactive polyphenols EGCG may be considered a functional food in reduced risk, progression, and treatment of fibromyalgia caused by overexpression of oxidative stress. However, the intake of green tea supplements should be taken with extreme care as acute liver toxicity has been reported in a number of medical literature.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Use of complementary and alternative medical therapies by patients referred to a fibromyalgiatreatment program at a tertiary care center by Wahner-Roedler DL1, Elkin PL, Vincent A, Thompson JM, Oh TH, Loehrer LL, Mandrekar JN, Bauer BA.(PubMed)
(2) Oxidative stress and mitochondrial dysfunction in fibromyalgia by Cordero MD1, de Miguel M, Carmona-López I, Bonal P, Campa F, Moreno-Fernández AM(PubMed)Molecular identification for epigallocatechin-3-gallate-mediated antioxidant intervention on the H2O2-induced oxidative stress in H9c2 rat cardiomyoblasts by Chen WC, Hsieh SR, Chiu CH, Hsu BD1, Liou YM.(PubMed)
(3) Molecular identification for epigallocatechin-3-gallate-mediated antioxidant intervention on the H2O2-induced oxidative stress in H9c2 rat cardiomyoblasts by Chen WC, Hsieh SR, Chiu CH, Hsu BD1, Liou YM.(PubMed)

#Healthyfood #Cranberry May Improve the Postprandial Blood Glucose in High Fat Diet, Researchers Find

By Kyle J. Norton

Postprandial blood glucose is the range of blood glucose that is measured by the blood glucose test, taken after 2 hours of a meal.

At this point of measurement, postprandial blood glucose in a healthy individual usually goes back down. In other words, lower or equal to 7.8 mmol/L (140 mg/dL) 2 hours after eating are normal blood glucose found in a healthy individual.

Glycemic response is a change in blood glucose after consuming a carbohydrate-containing food compared to Glycemic Index (GI) which ranks carbohydrate-containing foods, according to their effect on blood glucose levels.

In other words, the glycemic response is the change of blood glucose after the intake of a food or meal.

More precisely, healthy people who do not have prediabetes or diabetes have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period.

According to the 2015 statistics by the American Diabetes Association, in the U.S. over 30.3 million Americans, or 9.4% of the population are living with diabetes. Sadly, out of 30.3 million adults with diabetes, 23.1 million were diagnosed, and 7.2 million were undiagnosed.

In 2015, 84.1 million Americans age 18 and older had prediabetes.

According to epidemiological studies, by managing postprandial blood glucose effectively, diabetics can decrease the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of diabetes, researchers investigated the postprandial effects of dried cranberries following a high-fat breakfast challenge in obese participants with type 2 diabetes (T2DM).

The randomized crossover trial includes blood draw and vascular measurements such as fasting, 1, 2, and 4 hours (h), following the consumption of a fast-food style high-fat breakfast (70 g fat, 974 kcal) with or without cranberries (40 g).

According to the results of the analysis, biomarkers associated with inflammation and oxidative markers such as interleukin-18 and malondialdehyde were significantly lower at 4 h.

Serum total nitrite was found to be higher at 2 h in the cranberry compared to the control group.

However, there were no significant differences in levels of insulin, insulin resistance, lipid profiles, and blood pressure between the cranberry and control group.

Furthermore, cranberries showed no effect on the levels of C-reactive protein or interleukin-6.
In other words, dietary cranberries inhibited the high-fat breakfast-induced postprandial glucose and selected biomarkers of inflammation and oxidation in patients with T2DM without affecting other parameters associated with diabetes such as insulin, insulin resistance, lipid profiles, and blood pressure.

Based on the findings, researchers said, "Adding whole cranberries to a high-fat meal may improve postprandial blood glucose management and warrant further investigation".

Taken altogether, cranberry may be considered a remedy used for postprandial blood glucose management, pending t the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography

Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberries improve postprandial glucose excursions in type 2 diabetes buSchell J1, Betts NM, Foster M, Scofield RH, Basu A. (PubMed)
(2) Impact of Cranberry Juice Enriched with Omega-3 Fatty Acids Adjunct with Nonsurgical Periodontal Treatment on Metabolic Control and Periodontal Status in Type 2 Patients with Diabetes with Periodontal Disease by Zare Javid A1, Maghsoumi-Norouzabad L1,2,3, Ashrafzadeh E1,2,3, Yousefimanesh HA4, Zakerkish M5, Ahmadi Angali K6, Ravanbakhsh M2, Babaei H. (PubMed)

#Antioxidant #Indicaxanthin In the Prevention of #Diseases Associated with #Atheromas, Researchers Find

By Kyle J. Norton

An atheroma, or atheromatous plaque ("plaque"), is an abnormal accumulation of plaque in the inner layer of the wall of an artery, found in most adults, a leading cause of atherosclerosis.
Atherosclerosis is a condition caused by long-term plaques built-up on the wall of the arteries, leading to the narrowing arteries, a major cause of cardiovascular disease (CVD)

CVD is a medical condition involved in blood vessels. CVD can be heart disease or stroke depending on the location of a blood clot that causes blockage of the blood flow in the artery.

According to the statistics provided by the European Heart Network, cardiovascular disease (CVD) causes 3.9 million deaths in Europe and over 1.8 million deaths in the European Union (EU) every year. In 2015, approximately, 11.3 million new cases of CVD in Europe and 6.1 million new cases of CVD in the EU were diagnosed.

Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.

Atheromatous plaques build up in the arteries can be classified into several stages, including
* Stage 1 is the foam cells of macrophage and fatty deposits are localized on blood vessel walls.

* Stage 2 Type II is various thread-like fibers or filaments accumulated on the arterial wall.

* Stage 3 is connective tissue deposition on the arteries is thicker.

Stage 1-3 is most frequently found in patients with hypertension, diabetes mellitus, hypercholesterolemia, and who smoke.

* Stage 4 and 5 Type IV and V are conditions that the softer plaque with a thinner fibrous cap containing macrophages and smooth muscle cells are formed.

Atherosclerosis at the early stage is asymptomatic. However, in stage 4 and 5, patients may experience symptoms of chest pain, pain in their leg, and arm, particularly in the area of a blocked artery, shortness of breath, fatigue muscle weakness due to reduce blood flow in the artery.

Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.

In finding a potent compound for the treatment of atheromas, 7-Ketocholesterol (7-KC)-induced apoptosis of macrophages is considered a key event in the development of human atheromas.

In human atheromatous by the 7-Ketocholesterol (7-KC), researchers found that* The induction of atheromatous plaque within 24 h of injection of 7-KC was associated with the induced cytotoxicity by elevating the expression of intracellular reactive oxygen species over basal levels.
* Furthermore, levels of preceding NADPH oxidase-4 (NOX-4) over-expression and elevation of cytosolic Ca²⁺ associated with an imbalanced ratio of free radicals and antioxidants were also induced by the administration of 7-KC.

* Moreover, the progressive depletion of total thiols that cause oxidative stress was also promoted by the 7-KC
* Additionally, the redox-sensitive NF-κB involved in the inhibition of oxidation was also de-promoted by 7-KC activation.

* Co-incubation of 2·5 μm of Ind not only completely prevented 7-KC-induced pro-apoptosis in the tested cells but also decreased the parameters that lead to the risk of atheromas.

Based on the findings, researchers said, "( Indicaxanthin( a highly bioavailable dietary phytochemical, may exert protective effects against atherogenesis toxicity of 7-KC at a concentration of nutritional interest".

Taken altogether, indicaxanthin may be considered a remedy for the prevention and treatment of atheromas, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress by Tesoriere L1, Attanzio A, Allegra M, Gentile C, Livrea MA. (PubMed)

#Phytochemicals #Betaxanthins Reduce the Risk of Diseases Associated with Narrowing Arteries, According to Studies

By Kyle J. Norton

Stenosis of the arteries is a narrowing large artery caused by the accumulation of plaques located on each side of the neck that carries blood to the head, face, and brain.

The most common causes of stenosis of the arteries are results from atherosclerosis.

Untreated stenosis of the arteries has been found to induce complications of transient ischemic attack or stroke, depending on a blot clot that briefly blockage or partly or completely blockage of a blood vessel to the brain.

Atherosclerosis is a medical condition caused by plaque accumulated on the wall of arteries, leading to the narrowing of the artery and reducing oxygen risk blood flow to the heart and brain.

Depending on the location of the blockage, if the reduced blood flow occurred in the brain, it will cause the death of the brain cells, leading to stroke.

However, if the reduced blood flow occurred in the heart, it will cause damage to the heart tissues, leading to heart disease.

The Most common disease associated with atherosclerosis is coronary artery disease. Plaques are made up of cholesterol, calcium, and other chemical substances in the artery

Most people with atherosclerosis are asymptomatic at the early stage.

Some researchers suggested that atherosclerosis is a lipoprotein-driven disease. Therefore, people with high blood cholesterol are at an increased risk of atherosclerosis. Overuse of calcium supplements is also found to elevate the condition risk, particularly in the elderly.

Other risk factors that have been found epidemiologically by studies are high blood pressure, triglycerides, smoking, insulin resistance, obesity or diabetes, and inflammatory diseases, such as arthritis, lupus, or infections.

Most cases of atherosclerosis can be reversed by making a change of lifestyle and moderate exercise. However, in severe cases, surgery to remove plaque from the artery may be the only option.

Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.

On finding a potent ingredient for the treatment of cardiovascular disease, researchers investigated the effects of betalains, consisting of betacyanins and betaxanthins on the stenosis of the arteries.

In vivo and in vitro studies, betalains and betalain-rich diets are not only safe but also inhibited oxidative stress-, inflammation-, and dyslipidemia-related diseases associated with narrowing arteries involved in atherosclerosis, or a build-up of plaque on the inside of the arteries.

Furthermore, betalains and betalain-rich diets are safe toxicological safety, incorporated with easy accessibility, low price, biodegradability, and potentially advantageous biological effects on health.

These results strongly suggested betalains may be used in food manufacturing and related industries to overcome current concerns over the health risks of artificial colors.

Dr. Rahimi P, the lead scientist wrote, "(Even with the efficacy), further studies using pure betalains are required to gain a deeper understanding of their precise biological functions".

Taken altogether, betaxanthins found abundantly in betalains and betalain-rich diets may be considered anti-atherosclerotic remedies, pending the confirmation of a larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton'sProfessional's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Betalains, the nature-inspired pigments, in health and diseases by Rahimi P1, Abedimanesh S1, Mesbah-Namin SA1, Ostadrahimi A. (PubMed)

#Herbal #TurmericExtracts Process Significant Antioxiant Effects on Inflammation, Researchers Find

By Kyle J. Norton

Inflammation is a systematic immune response associated with the production of proinflammatory cytokine activated by the white blood cells in the first line of defense.

In the early phase of bodily injury and damage, the reaction of the immune system also encompasses a wide range of pathophysiological responses to minimize tissue damage while enhancing the repair process.

Inflammation also can be caused by viruses and bacteria, some of the most common stimuli of inflammation. However, overproduction of pro-inflammatory cytokines initiated by the immune system for a prolonged period may lead to cell damage and sometimes death of the healthy cells in the infectious site and nearby cells.

Badly enough, some proteins process the duo functions of pro and anti-inflammation. Under abnormal conditions, they can switch from their original action of anti-inflammatory cytokines to pro-inflammatory cytokines.

The complications involved in the overproduction of pro-inflammatory cytokines induced improper healing for the forming of scars and damage to the tissue of the organ can also affect and limit the organ functioning, such as liver scars caused by hepatitis virus infection.

Malfunctioning immunological responses attack the body tissue, and can incite inappropriate and chronic inflammation

Believe it or not, tissues die from a lack of oxygen or nutrients associated with oxidative stress overload can also cause inflammation.

Chronic inflammation in the hand is caused by the immune response that can not kill off all infectious agents in the acute phase of infection.

Some researchers argued that the evolution of the immune system is to kill off all infectious stimuli or pathogens within 3 - 8 weeks, otherwise, the immune system will adapt to their existence, in other words, chronic inflammation.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, and wound healing agent, and for the treatment of flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the treatment of diseases associated with inflammation, researchers examined the efficacy of a hot water extract of C. longa (WEC) or bisacurone, a component of turmeric extract with antioxidant and anti-inflammatory activity.

On C57BL/6 mice-induced liver injury by acute ethanol, administration of WEC (20 mg/kg body weight; BW) or bisacurone (60 µg/kg BW) at 30 min before a single dose of ethanol(3·0 g/kg BW), researchers found that plasma levels of aspartate aminotransferase and alanine aminotransferase elevated in ethanol-treated mice was significantly suppressed by WEC and bisacurone.

Furthermore, mice treated with WEC also protected the hepatic tissue by increasing the levels of antioxidants superoxide dismutase and glutathione.


Moreover, hepatic tissue levels of thiobarbituric acid-reactive substances. and associated with reduced levels of oxidation, proteins TNF-α protein, and IL-6 mRNA involved in the production of pro-inflammatory cytokines were also inhibited by WEC and bisacurone, compared to control mice.

In other words, WEC and bisacurone protect the liver cell by inhibiting the parameters against the induction of oxidative stress.

Conclusively, researchers said, " oral administration of WEC may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation, at least partly through the effects of bisacurone".

Taken altogether, turmeric-processed abundantly bioactive compound bisacurone may be considered supplements for the prevention and treatment of diseases associated with inflammation, pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Hot water extract of turmeric (Curcuma longa) prevents non-alcoholic steatohepatitis in mice by inhibiting hepatic oxidative stress and inflammation by Uchio R1, Murosaki S2, Ichikawa H. (PubMed)
(2) A hot water extract of turmeric (Curcuma longa) suppresses acute ethanol-induced liver injury in mice by inhibiting hepatic oxidative stress and inflammatory cytokine production by Uchio R1, Higashi Y1, Kohama Y2, Kawasaki K1, Hirao T2, Muroyama K1, Murosaki S. (PubMed)

Coffee and Coffee Caffeine Intake Daily Without Adding Milks are Associated with An Increased Risk of Osteoporosis, Researchers Suggest

By Kyle J. Norton

Increased lifelong intake of coffee caffeine may have a potential effect in reduced bone mineral density in menopausal women, a Southern America University opinionated.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a prolonged period.

A study to investigate whether increased coffee intake expressed a linear effect in the risk of increased aging bone density of 980 postmenopausal women aged 50 to 98 years (mean age, 72.7 years) in a  community-based population of older women, Rancho Bernardo, Calif. participated between 1988 and 1991, researchers showed that women drinking coffee without adding milk have a strong effect in risk of osteoporosis, but for women drinking at least one cup of milk a day, coffee caffeine intake does not impede bone density.

Dr. Barrett-Connor E, the lead author said, "Lifetime caffeinated coffee intake equivalent to two cups per day is associated with decreased bone density in older women who do not drink milk daily".

Other, in the measured the bone density of both hips and the total body in 138 healthy, postmenopausal women aged 55-70 y who never used hormone replacement therapy, returned reports including current and long-time caffeinated beverages, suggested that with the same anthropometric and nutrient intakes, caffeine intake was not associated to osteoporosis regardless numbers of cups drinking per day.

Interestingly, based on brewed beverages chemical analysis, most computer models have overestimated the caffeine intake of prospects by nearly two-thirds.

Based on the findings, Dr. Lloyd T. the lead author said, " The habitual dietary caffeine intake of this cohort of 138 postmenopausal women ranged from 0-1400 mg/d and was not associated with the total body or hip bone mineral density measurements".

Furthermore, according to the Creighton University, School of Medicine study of cross-sectional measurements of BMD in 489 elderly women (aged 65-77 y) and from longitudinal measurements made in 96 of these women who were treated with coffee in compared to a placebo for 3 y. showed a nonlinear result of osteoporosis risk increased in women drinking over < or =300 mg/d in compared to low and moderated groups.

The study also specified that all 3 groups showed some forms of bone density loss, and higher bone density loss is correlated to cups of coffee drinking per day.

Particularly, Dr, Rapuri PB, said, "Intakes of caffeine in amounts >300 mg/d ( approximately 514 g, or 18 oz, brewed coffee) accelerate bone loss at the spine in elderly postmenopausal women".

Taking it all together, menopausal women may have an increased risk of mineral bone density in the induction of osteoporosis for drinking >300 mg/day. Due to conflicting results from the above studies, further confirmation with large size and multi centers studies are necessary.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Coffee-associated osteoporosis offset by daily milk consumption. The Rancho Bernardo Study by Barrett-Connor E1, Chang JC, Edelstein SL. (PubMed)
(2) Dietary caffeine intake and bone status of postmenopausal women by Lloyd T1, Rollings N, Eggli DF, Kieselhorst K, Chinchilli VM. (PubMed
(3) Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes by Rapuri PB1, Gallagher JC, Kinyamu HK, Ryschon KL. (PubMed)

#Healthyfood #Garbanzobeans(#Chickpeas) in the Promotion of #BowelHealth, Scientists Say

By Kyle J. Norton

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has played an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

People who follow a typical American diet may express a specific problem in bowel movement, as a result of consuming high saturated fat, salt, sugar....... and less fiber. According to the University of Tasmania, diet not only affects food choice, and satiety but also has a profound influence on bowel health. 15 participants in the study tended to eat more processed snack foods (high energy, low fiber) after ceasing chickpea consumption(1).

In 27 free-living adults who followed two randomized, crossover dietary interventions each of five weeks duration, Dr. Pittaway JK and the research team said,"... significant decrease in serum TC and LDL-C during the chickpea diet compared to the equivalent fiber wheat diet was partly due to unintentional changes in macronutrient intake occurring because of chickpea ingestion"(2).

The effect of chickpeas in the promotion of bowel health may be the result of the high amount of dietary fiber found in the peas. The study of the effectiveness of probiotics, prebiotics, and dietary fiber in the treatment of FGD in the pediatric population, suggested that the administration of a fiber supplement is more effective than a placebo for the treatment of childhood constipation(3).

In fact, Fiber undergoes partial or total fermentation after conscription in the distal small bowel and colon leading to the production of short-chain fatty acids and gas, thereby affecting gastrointestinal function and sensation, the University of Michigan Health System, insisted(4).

Taking it all together, people who eat a portion of chickpeas daily may improve their gastrointestinal function, regardless of the type of diet.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the KJarate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Chickpea supplementation in an Australian diet affects food choice, satiety, and bowel health by Murty CM1, Pittaway JK, Ball MJ. (PubMed)
(2) Effects of a controlled diet supplemented with chickpeas on serum lipids, glucose tolerance, satiety, and bowel function by Pittaway JK1, Ahuja KD, Robertson IK, Ball MJ. (PubMed)
(3) Probiotics, prebiotics, and dietary fiber in the management of functional gastrointestinal disorders by Horvath A1, Szajewska H.(PubMed)
(4) Fiber and functional gastrointestinal disorders by Eswaran S1, Muir J, Chey WD. (PubMed)