#Herbal #Ashwagandha Shows a Significant Effect on #ColonCancer in Vitros and Vivos, According to Studies

By Kyle J. Norton

Cancer is a group of chronic diseases caused by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.

Colon cancer is a chronic condition characterized by uncontrolled cell growth in the colon tissue.

Most cases of colon cancer start with the alternation of cells DNA in the cells on the surface of the inner lining colon tissue before proliferating into deeper tissues to form a tumor through abnormal cell cycle division.

The colon formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.

Colon cancer is relatively very common, slowly growing, and progressing cancer.

According to the statistics provided by the American Cancer Society, in 2019, colorectal cancer including colon and rectal cancer is the third most common cancer diagnosed in both men and women in the United States.

In 2019, 101,420 people in the US will be diagnosed with colon cancer.

The most common symptoms of colon cancer are a persistent change in your bowel habits, including diarrhea or constipation, blood in your stool, and persistent abdominal discomforts, such as feeling that your bowel doesn't empty completely accompanied by some general symptoms shared by other types of cancer.

The exact causes of colon cancer are unknown. However, out of many risk factors associated with the onset of the disease, aging may have a strong implication involved in cancer, as most cases of colon are found in the older population.

Dr. O Ng and colleagues in a joint study led by the University of Nottingham wrote, "The prevalence of colorectal cancer is increasing in the elderly. We examined the treatment and outcomes in our institution of patients aged over 85 years with proven colorectal adenocarcinoma".


Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potential compound for the treatment of colon cancer with no side effect, researchers examined the effects of Withaferin-A, a withanolide derived from the leaf extract of W. somnifera, anti-colon tumor activity.

On human colorectal cancer (HCT116) cells, the phytochemical not only inhibited the proliferation but also the migration of the tested cancer cells in a concentration-dependent manner.

In other words, Withaferin-A exhibited cell cycle arrest and blocked cancer cell spreading.

Furthermore, the administration of withaferin-A attenuated the expression of pro-inflammatory cytokines activated by protein (STAT3) associated with the development and progression of colon cancer.

On HCT116 cells xenograft tumors generated in Balb/c nude mice, withaferin-A showed a strong activity in which a significant decrease in the volume and weight of tumors, compared to untreated controls.

Based on the finding, researchers said, "The present study suggests that withaferin-A holds the potential to be developed as a small molecule inhibitor of STAT3 for the treatment of HCT116".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of colon cancer in vitro and vivo.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
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Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)
(2) Immunomodulatory effects of Withania somnifera on azoxymethane-induced experimental colon cancer in mice by Muralikrishnan G1, Dinda AK, Shakeel F. (PubMed)
(3) Colorectal cancer outcomes in patients aged over 85 years by O Ng,1 E Watts,2 CA Bull,2 R Morris,3 A Acheson,2 and A Banerjea. (PMC)

#Lycopenes Exhibit Antioxidant Activities Against the Risk of #HepaticSteatosis and #NonAlchololicFattyLiverDisease In Vivos

By Kyle J. Norton

The liver is the largest internal organ that filters the blood from the digestive tract, before passing them to the rest of the body.
The liver also plays an essential role to produce cholesterol to build a strong cell wall, produce steroid hormones and vitamin D and aid the digestive function in food absorption and detoxify chemicals and metabolizes drugs.

Hepatic steatosis is a medical condition that reduces the function of the liver caused by the accumulation of fat in the liver.


In other words, if the intrahepatic fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Epidemiologically, over time, untreated hepatic steatosis can lead to liver metabolic dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease.

Hepatic steatosis has been found to induce complications in patients with obesity, alcohol intoxication and/or hepatic disorders.

Most common risk factors associated with the onset of hepatic steatosis are insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN).

The increased flux of fatty acids to the liver, de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion are some mechanisms that cause the accumulation of intrahepatic fat.

Out of many prevalent factors involved in the onset of hepatic steatosis, some researchers suggested that the promotion of the Western diet over the past few decades in the Western world may have a strong and negative impact that accelerates the incidence onset.

Dr. Michael D. Roberts, the lead scientist said, "Six weeks of WD feeding caused hepatic steatosis development as evidenced by the 2.25-fold increase in liver triacylglycerol content,...in adult Brown Norway rats".

And, "sub-chronic WD feeding appears to increase hepatic steatosis development over a 6-week period but only induces select inflammation-related liver transcripts, mostly acute phase response genes".

Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the prevention of liver disease, researchers examined the effects of lycopene on hepatic steatosis in an animal model.

In a model of high-fat diet rats, lycopene not only showed a significant effect against the development of steatohepatitis but also inhibited nonalcoholic steatohepatitis (NASH) in the promotion of the early stage of liver cancer through its antioxidant activity.

In rats induced NAFLD by a hypercholesterolemic and high-fat diet, according to the tested analysis, after 7 weeks, there are clear differences in the classical antioxidant biomarkers and metabolic pattern associated with the inhibition of NAFLD between the diet and intake of lycopene from tomato juice.

Interestingly, tomato juice administration partially reverted the metabolic pattern from a high-fat diet to a normal diet in metabolites without exhibiting the redox state.

Taken altogether, lycopene found in tomatoes may be considered a supplement for the improvement of liver metabolism against the risk of liver disease, pending the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months)

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ. (PubMed)
(2) Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice by Ip BC1, Liu C2, Lichtenstein AH3, von Lintig J4, Wang XD. (PubMed)
(3) Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown Norway rats by Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu,Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins,Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth, and R. Scott Rector. (PMC)

#Antioxidant #Quercetin Found in #Onion Inhibits Parameters that Cause #CardiovascularDiseases, According to Studies

By Kyle J. Norton

Vasoprotection is the process to improve the function of the blood vessels, including the use of herbal and natural remedies.
Blood vessels are the tubular structure including a vein, artery, or capillary which carries the blood through the tissues and organs pumped by the heart.

There 3 main types of blood vessels arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body. Damage of arteries may induce coronary artery disease associated with the narrowing or blockage of the coronary arteries due to plaques accumulated on the arterial wall.

The veins carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with a disease of the veins that affects up to 20 percent of adults.

The capillaries or the smallest blood vessels that have been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.


Endothelial dysfunction is a condition characterized by the damage of the vascular endothelium, the thin layer of cells that lines blood vessels, a leading cause of cardiovascular disease (CVD).

In other words, vascular endothelium dysfunction reduced the function of targeting free radicals that lead to the onset of oxidative stress.

The most common risk factors associated with vascular endothelium dysfunction are impaired vasodilation, deficiency of nitric oxide, inflammation, and thrombosis.

Conventionally, treatments of vascular endothelial dysfunction are totally depending on the causes of the disease. Early detection has been found to play a critical role that recovers endothelial function".

Dr. Hirata Y. at The University of Tokyo.wrote, "Vascular endothelial dysfunction reflected by reduced nitric oxide (NO) availability is certainly the causative factor or promoting mechanism of arteriosclerosis. It is necessary to detect endothelial dysfunction at an early stage using appropriate methods, and to choose a treatment for the recovery of endothelial function".

And, "There are nonpharmacological and pharmacological therapies to attain endothelial repair. The former includes bodyweight reduction, aerobic exercise, and restriction of salt intake, while the latter includes the use of renin-angiotensin system inhibitors, calcium antagonists, some types of beta-blockers, statins, erythropoietin, tetrahydrobiopterin, and antioxidants".


The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.

On finding a potent ingredient that processes vasoprotective activity researchers examined quercetin, a dietary polyphenol found abundantly in onion on vascular endothelial dysfunction (VED).

Epidemiologically, quercetin showed significant activity against the VED complication in the induction of oxidative stress, impaired vasodilation, platelet aggregation, and monocyte adhesion leading to the early event of morbidity and mortality in patients with cardiovascular disease (CVD).

Quercetin efficacy which protects against VED and decreases CVD risk was attributed to its antioxidant, vasodilatory, anti-platelet, and anti-atherogenic activities.

Furthermore, in vitro, quercetin exerted multiple actions on the NO-guanylyl cyclase pathway associated with the smooth muscle tone in bronchi or vessels, endothelium-derived hyperpolarizing factor(s), and endothelin-1 involved in vasoconstriction and endothelial function.

Moreover, the phytochemical also protected endothelial cells against apoptosis.

In vivo, quercetin prevented endothelial dysfunction by reducing blood pressure, oxidative stress, and end-organ damage in hypertensive animals.

In other words, regular intake of quercetin improves the endothelium functioning against the risk of VED-inducing cardiovascular disease, particularly in patients with hypertension and ischemic heart disease.

Taken altogether, onion processed with a higher amount of quercetin may be considered a remedy for the prevention and treatment of vascular endothelial dysfunction, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Vasoprotective activities of quercetin by Richard S Bruno. (Research Gate)
(2) Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols by Perez-Vizcaino F1, Duarte J, Andriantsitohaina R. (PubMed)
(3) Diagnosis and treatment of endothelial dysfunction in cardiovascular disease by Hirata Y1, Nagata D, Suzuki E, Nishimatsu H, Suzuki J, Nagai R. (PubMed)

#Healthyfood #BlackBeans Show an Reduced Risk and Treatment of #LiverCancer in Vivos, Researchers Say

By Kyle J. Norton

Intake of black beans regularly may have a profound effect on reduced risk and treatment of liver cancer, a renowned institute study proposed.
Liver cancer is a condition of the abnormal growth of the cells in the liver's tissue. According to statistics approximately 40,710 adults (29,200 men and 11,510 women) in the United States will be diagnosed with primary liver cancer this year.

Black beans, small roughly ovoid legumes with glossy black shells, genus Phaseolus, and belongings to the family Fabaceae can buy in most grocery stores all around the year in dried and canned forms. It is believed that black bean was the first domesticated growth in South America.

According to Stocking Hall, Cornell University, phytochemicals isolated from black beans such as triterpenoids, flavonoids, and other compounds exhibited antiproliferative activities against the HepG2 cells, the human liver cancer cell line.


The efficacy of black beans in ameliorating the growth of liver cancer may be attributed to the presence of some potent antioxidants in the expression of apoptosis.

Furthermore, the consumption of beans not only played a prominent role in gene expression involved in the regulation of gene Hspa8 in reduced risk of liver disease developed but also addressed the important issue of attenuated hepatic stress or toxicity in a rat model.

In fact, increased bean consumption in rats exhibits changes indicative of hepatic damage, Dr. Daniell EL, the lead author said, "Dry bean (Phaseolus vulgaris L.) consumption is associated with reduced risk for a number of chronic diseases", such as liver cancer.
More interestingly, dietary bean concentrations.is found to associate with the cholesterol 7α hydroxylase and UDP-glucuronosyltransferase genes increased with connection to the development of liver cancer, in a dose-dependent manner.

These findings suggested that dietary black(dried) beans may have a potential effect in reducing the risk and treatment of liver cancer through antioxidant activity and regulated genes involved in the early onset of the disease.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Sources
(1) Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activities by Dong M1, He X, Liu RH. (PubMed)
(2) Dietary dry bean effects on hepatic expression of stress and toxicity-related genes in rats by Daniell EL1, Ryan EP, Brick MA, Thompson HJ. (PubMed)

#GreenteaExtract #EGCG Reduces the Symptoms and Risk of #ColdSore, Scientists Say

By Kyle J. Norton

Green tea may have a therapeutic and positive effect in reducing the risk and treatment of cold sore (herpes simplex labialis infection), some scientists suggested.


Cold soreness is a common skin disease characterized by tiny blisters that develop on the lips or around the mouth caused by the infection of herpes simplex virus strain HSV-1 mostly.

Believe it or not, over 80% of the North American population have herpes 1 virus living permanently in their body without causing any health problems. However, the dormant virus can quickly multiply to affect the skin on the lips if the immune system is weakened or triggered by certain conditions such as prolonged stress, or a digestive disorder.

The virus is very contagious, anyone who comes to direct contact with an infected person can easily be infected.

The most common symptoms of cold sore include sensations, tingling,,...... pain, or numbness on the lip and skin surrounding the lip.

A cold sore that appears inside the mouth may be troublesome, as the condition interferes with food injection and speech.

In a number of severe cases, herpes 1 virus may infect the eye, and brain, leading to vision loss and certain brain infectious diseases.

Conventional antiviral medicine used for the treatment of cold sores may be effective such as Zovirax, Famvir,..... and valacyclovir, but they can induce certain side effects including digestive discomfort,..., headache, dizziness,.... and tiredness.

In the reaffirmed the efficacy of catechins from the tea plant (Camellia sinensis) therapeutic effect on herpes simplex virus infections in vitro and in vivo, researchers conducted a double-blind, placebo-controlled, randomized trial with 40 participants.

The aim of the joint study is to clinically evaluate a topical proprietary formulation containing lipophilic catechins (AverTeaX, Camellix, LLC, Evans, GA, USA) on recurrent herpes labialis.

In comparison to the vehicle group treated with 100% glycerin USP, CVS Pharmacies, Inc., Woonsocket, RI, USA), topical application of AverTeaX applied six to eight times daily showed a strong reduction in clinical episode duration (median 4.5 days vs. 9 days) and shortened blistering and ulceration stages within an episode from a median of 3 days to 1 day.

According to the median quality-of-life scores, AverTeaX treated group demonstrated with respect to duration of itching, from a median of 4 days to 1 day, and duration until symptom-free, from a median of 8 days to 4 days.

Interestingly, both groups displayed similar in median scores for itching, pain, burning, swelling, bleeding, and stress.

No adverse effects were found in both groups, during the term of study.

Based on these results, Dr. Zhao M, after taking into account other co-founders, said, "AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance".

Additionally, in further analysis to address the green tea extract in reduced expression of HSV in precipitated risk of skin infection, including cold sore and reconfirmed EGCG anti-oxidant activity in an inhibited number of plaques in HIV-infected cultured cells, a study to evaluate the efficacy of modified EGCG palmitoyl-EGCG (p-EGCG), as a topical antiviral agent for Herpes Simplex Virus (HSV-1) infections was conducted.

p-EGCG is not toxic to cultured Vero cells, according to the cell viability and cell proliferation assays

According to the results, the application of p-EGCG increased the effectiveness of EGCG as an antiviral agent.

In comparison to EGCG topically applied to the skin, one of the primary tissues infected by HSV, green tea polyphenol epigallocatechin gallate (EGCG) with palmitate was a more potent inhibitor of Herpes Simplex Virus 1 (HSV-1).

Observation of other assays used in the experiment, p-EGCG concentrations of 50 µM or higher exerted linearly in blocking the production of infectious HSV-1 particles.


This efficacy suggested that p-EGCG may be considered a potent and natural ingredient in inhibited HSV-1 adsorption to Vero cells.

Thus, p-EGCG may provide a novel treatment for HSV-1 infections, including cold sores.

The findings suggested that topically green tea used a combination with other herbal ingredients or green tea extract used alone may have a therapeutic potential in the treatment of cold sores caused by herpes simplex virus HSV-1 infection)


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca




Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.


Sources
(1) Topical lipophilic epigallocatechin-3-gallate on herpes labialis: a phase II clinical trial of AverTeaX formula by Zhao M1, Zheng R1, Jiang J1, Dickinson D2, Fu B1, Chu TC3, Lee LH4, Pearl H5, Hsu S6.(PubMed)
(2) Inhibition of Herpes Simplex Virus type 1 with the modified green tea polyphenol palmitoyl-epigallocatechin gallate by Aline de Oliveira,a Sandra D. Adams,b Lee H. Lee,b Sean R. Murray,c Stephen D. Hsu,d Jeffrey R. Hammond,cDouglas Dickinson,d Ping Chen,e and Tin-Chun Chua(PMC)

#Healthyfood #Chickpeas Improve Glucose Metabolism and Increase Insulin Sensitivity in Patients with Diabetes, According to Studies

By Kyle J. Norton

Garbanzo beans also known as chickpeas are an edible legume of the genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate glucose. It is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

The effectiveness of chickpeas in reduced the risk of type II diabetes, is probably due to the existence of a high amount of dietary fiber. According to Case Western Reserve University, increased consumption of soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals.

People who follow high-fiber, high-carbohydrate diets over time, can see the benefits in controlling body weight, insulin requirements, glycemic control, and serum lipids up to 10 years of follow-up.

In the review of 14 randomized clinical trials, Dr. Wolfram T and the research team found that the addition of insoluble or soluble fiber to meals, increased consumption of diets rich in whole grains and vegetables, and vegan diets improve glucose metabolism and increase insulin sensitivity. The greatest improvement in blood lipids, body weight, and hemoglobin A(1c) level occurred in participants following low-fat, plant-based diets.

In fact, " High-fiber diets, especially of the soluble variety, and soluble fiber supplements may offer some improvement in carbohydrate metabolism, lower total cholesterol, and low-density lipoprotein (LDL) cholesterol and have other beneficial effects in patients with non-insulin-dependent diabetes mellitus (NIDDM)", Dr. Vinik AI and Dr. Jenkins DJ said.

Furthermore, The American Diabetes Association recommends a goal of 40 g of soluble fiber intake per day for a patient with diabetes.

Taking all together, chickpeas with a high amount of dietary fiber may be considered as a functional food in reducing the symptoms and complications of patients with diabetes.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Efficacy of high-fiber diets in the management of type 2 diabetes mellitus by Wolfram T1, Ismail-Beigi F.(PubMed)
(2) Type II diabetes: current nutrition management concepts by Anderson JW, Gustafson NJ.(PubMed)
(3) Efficacy of high-fiber diets in the management of type 2 diabetes mellitus by Wolfram T1, Ismail-Beigi F.(PubMed)
(4) Dietary fiber in management of diabetes, by Vinik AI1, Jenkins DJ.(PubMed)
(5) The dietary treatment of diabetes mellitus by Bantle JP1.(PubMed)

Curcumins Found in Turmeric Decrease the levels of Hyperlipidemia by Reducing Body-LIver-Adipose Weight in Vivos, Researchers Say

By Kyle J. Norton

Hyperlipidemia is a chronic condition of abnormally high levels of any or all lipoproteins in the bloodstream, including cholesterol and triglycerides.
The condition is normally known as high blood cholesterol in the general population.

People with hyperlipidemia are asymptomatic. Over time, the fat collection in the arteries accompanied by calcium or other substances forms plaque, leading to narrowing arteries and reduced function of the arteries to transport oxygen-rich blood to the parts of the body.

According to the statistics provided by the CDC, in 2015–2016, more than 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

Believe it or not, about half of U.S. adults (55%, or 43 million) are currently taking medicine associated with lower blood cholesterol.

There are many risk factors that cause the onset of hyperlipidemia, such as people with diabetes, overweight gain, physical activity, and smoking.

Some researchers suggested the promotion of a high-fat diet over the past decades may be one of the silent causes of hyperlipidemia in the Western world.

Dr. Charles Desmarchelier in the examined the risk of high blood cholesterol in a high-fat diet model said, "Mice on Western diet showed increased plasma cholesterol levels, associated with the higher dietary cholesterol supply, yet, significantly reduced cholesterol levels were found in intestine and liver".

And, "(The) intestine and liver react to a high dietary fat intake by activation of de novo cholesterol synthesis and other cholesterol-saving mechanisms, as well as with major changes in phospholipid metabolism, to accommodate to the fat load'.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, antiseptic, and wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural ingredient for the treatment of hyperlipidemia, researchers investigated the effects of curcumin on hyperlipidemia and hepatic steatosis in high-fructose-fed Wistar rats.

The study included 40 male Wistar rats divided into four groups with 10 rats. Two groups were fed with a standard rodent diet and the other two with a 60% high-fructose diet for 10 weeks. Curcumin (200 mg/kg body weight) was administered along with the diets simultaneously to each of the diets mentioned above groups.

After 10 weeks of the experiment, researchers found that curcumin decreased the levels of hyperlipidemia observed by reducing body weight, liver weight, and adipose weight.

The plasma levels of triglyceride by inhibited the proteins associated with fat cell fat metabolism, lipid ratios, and increased HDL-C (28.4 ± 4.5 mg/dL) in fructose-fed rats were also lower by the injection of curcumin.

Furthermore, curcumin also suppressed the lipogenic enzymes that regulate lipogenesis in fat cells.

Taken altogether, turmeric processed with a high amount of curcumin may be used for the prevention and treatment of hyperlipidemia, pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats by Maithilikarpagaselvi N1, Sridhar MG1, Swaminathan RP2, Sripradha R1, Badhe B. (PubMed)
(2) Highly bioavailable micellar curcuminoids accumulate in the blood, are safe, and do not reduce blood lipids and inflammation markers in moderately hyperlipidemic individuals by Kocher A1, Bohnert L1, Schiborr C1, Frank J, (PubMed)
(3) C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite plasma hypercholesterolemia by Charles Desmarchelier,1 Christoph Dahlhoff,1,2 Sylvia Keller,3 Manuela Sailer,1Gerhard Jahreis,3 and Hannelore Daniel. (PMC)