By Kyle J. Norton
Hypertension or high blood pressure, a condition associated with the cluster of metabolic syndrome is a medical condition associated with abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and changes constantly depending on activity. However, persistent hypertension due to poor management over time can lead to cardiovascular disease.
According to the statistics provided by the American Heart Association., nearly half of all adults in the United States are living with high blood pressure, or 1 in 3 Americans are hypertensive.
Hypertension is the leading risk factor for heart disease and stroke in the US.
Cardiovascular diseases (CVD) including heart disease and stroke are a class of conditions associated with the dysfunction of the arteries and heart, affecting the heart functioning.
According to the statistics provided by the CDC, heart disease is the leading cause of death for both men and women. Men are associated with 1/2 of the deaths due to heart disease in 2015 in men, compared to women.
Believe it or not, more than 63,000 Americans die from heart disease each year or 1 in every 4 deaths are caused by heart disease.
The most common prevalent factors associated with hypertension onset are family history, aging, being male, being overweight or obese, ethnicity, physical inactivity, unhealthy diet, and medical condition such as chronic kidney disease.
Excessive alcohol drinking is also one of the major causes besides obesity in elevating the syndrome onset.
Depending on the levels of blood pressure, most people with mild hypertension are asymptomatic. However, unmanaged high blood pressure can induce complications of heart attack or stroke, heart failure, weakened and narrowed blood vessels, metabolic syndrome, and trouble with memory or understanding,
Conventionally, blood pressure medications have been found to prevent many deaths from heart disease and stroke over the past 30 years, however, long-term intake of such medications has caused many side effects such as damaging the kidney.
Some researchers suggested by making changes to lifestyle, maintaining an ideal weight, and diet with low salt, you could do just fine without the drugs.
Dr. L. J. Beilin wrote, "Lifestyle factors are critical determinants of blood pressure levels operating against a background of genetic susceptibility. Excess body fat is a predominant cause of hypertension with additive effects of dietary salt, alcohol, and physical inactivity."
And "Controlled trials in hypertensives show blood pressure lowering effects of supplemental potassium, fiber, n-3 fatty acids, and diets rich in fruit and vegetables and low in saturated fats".
With an aim to find a natural food for the prevention and treatment of hypertension, researchers examined the effect of daily supplementation of kale juice can modulate blood pressure (BP).
The study included 84 subclinical hypertensive patients with systolic BP over 130 mmHg or diastolic BP over 85 mmHg who received 300 ml/day of kale juice for 6 weeks.
According to the blood samples obtained on 0-week and 6-week, kale supplements showed a significantly decreased systolic and diastolic blood pressure in all patients regardless of their GSTM1 or GSTT1 polymorphisms.
According to a joint study led by the Isfahan University of Medical Sciences, the GSTT1 and GSTM1 gene increases arterial pressure; hence, it can predict susceptibility to cardiovascular disease.
In other words, kale supplements inhibited the hyperactive parameters without being affected by the gene expression of GSTM1 or GSTT1 polymorphisms.
Furthermore, kale supplements exerted no effect on the plasma lipid profiles of patients with GSTM1-null and GSTM1-present genotypes.
More importantly, the supplement also increased plasma HDL-C and lowered LDL-C in the GSTT1-present type, while blood glucose was decreased only in the GSTT1-null genotype.
Based on the findings, researchers suggested, kale processes a strong effect in lowering blood pressure through other mechanisms, regardless of GSTT1 and GSTM1 gene types.
Taken altogether, kale juice may be considered a supplement for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effect of glutathione S-transferase M1 and T1 polymorphisms on blood pressure, blood glucose, and lipid profiles following the supplementation of kale (Brassica oleracea acephala) juice in South Korean subclinical hypertensive patients by Han JH1, Lee HJ1, Kim TS2, Kang MH. (PubMed)
(2) Association of GSTT1 and GSTM1 polymorphisms with blood pressure: A Bayesian modeling of continuous data by Laleh Rafee, Mahsa Abedini,1 Shaghayegh Haghjooy Javanmard, Nizal Sarrafzadegan,2 and Marjan Mansourian. (PubMed)
(3) Lifestyle and hypertension by L. J. Beilin, I. B. Puddey, V. Burke. (the American Journal of Hypertension)
Sunday, 4 June 2023
#Healthyfood #Eggplant Induces #ProstateCancerCell Apoptosis Through Cell Cycle Arrest, Researchers Find
By Kyle J. Norton
Eggplant may have a potential and substantial effect in reduced risk and treatment of prostate cancer, some scientists suggested.
Eggplant is a species of S. melongena with deep purple color, belongings to the family Solanaceae and native to India, cultivated in southern and eastern Asia since prehistory.
Prostate cancer is a medical condition characterized by irregular cell growth in the tissues of the prostate. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.
According to statistics, approximately 11.6 percent of men will be diagnosed with prostate cancer sometime during their lifetime.
In the investigation of the effect of glycoalkaloids nitrogen-containing secondary plant metabolites found in numerous Solanaceous plants including eggplants and the risk of cancer, researchers found that eggplant glycoalkaloids derivatives α-solamargine and α-solasonine inhibited prostate cancer and various types of cancer through induction of cancer cell apoptosis, a genetically directed process of cell self-destruction that involves numerous biomarkers and signaling pathways.
In vitro and in vivo application of glycoalkaloids derivatives α-solamargine and α-solasonine expressed a significant effect in inhibition of tumor formation and growth in fish and mice and human prostate cancer cell lines.
Indeed, in the human prostate cancer cell PC-3. administration of a non-toxic dose of α-solanine initiated cancer suppression and reduced the viability of the human cancer cell through significantly elevated epithelial marker E-cadherin gene expression in target mutated cells in the induction of cell proliferation and invasion and decreased mesenchymal marker vimentin expression in initiated cell metastasis.
Further differentiation, also suggested that α-Solanine ameliorated cancer cell proliferation and tumor initiation through reduced mRNA levels of matrix metalloproteinase-2 (MMP-2) and 9 (MMP-9) in stimulated cancer invasion and metastasis and increased the expression of reversion-inducing cysteine-rich protein with kazal motifs (RECK) in suppression of prostate tumor progression and tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2 in the regulation of MMP activity, particular in the induction of cancer cell overexpression.
According to the observation of the Immunoblotting assays, injection of α-solanine is effective in suppressing phosphorylation of phosphatidylinositide-3 kinase (PI3K) which plays an important role in modulated cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking involved cancer progression, Akt phosphorylates expression with primary functions is to promote cell growth and protein synthesis and The extracellular signal-regulated kinase (ERK) signaling pathway phosphorylates with function in the control of diverse cellular processes including such as proliferation, survival, differentiation, and motility.
Moreover, α-solanine reduced levels of microRNA-21 (miR-21) in the expression of cancer progression. Higher levels of miR-21 are correlated to more advanced malignancies and elevated tumor suppressor miR-138 expression in induced prostate cancer cells apoptosis through cell cycle arrest at G1/S transition.
Taken together, eggplant with abundant phytochemicals including glycoalkaloids derivatives α-solamargine and α-solasonine may be considered as a functional food in reduced risk and treatment of prostate cancer.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes by Friedman M1. (PubMed)
(2) α-Solanine inhibits invasion of human prostate cancer cells by suppressing epithelial-mesenchymal transition and MMPs expression by Shen KH1, Liao AC2, Hung JH3, Lee WJ4, Hu KC5, Lin PT6, Liao RF7, Chen PS8. (PubMed)
Eggplant may have a potential and substantial effect in reduced risk and treatment of prostate cancer, some scientists suggested.
Eggplant is a species of S. melongena with deep purple color, belongings to the family Solanaceae and native to India, cultivated in southern and eastern Asia since prehistory.
Prostate cancer is a medical condition characterized by irregular cell growth in the tissues of the prostate. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.
According to statistics, approximately 11.6 percent of men will be diagnosed with prostate cancer sometime during their lifetime.
In the investigation of the effect of glycoalkaloids nitrogen-containing secondary plant metabolites found in numerous Solanaceous plants including eggplants and the risk of cancer, researchers found that eggplant glycoalkaloids derivatives α-solamargine and α-solasonine inhibited prostate cancer and various types of cancer through induction of cancer cell apoptosis, a genetically directed process of cell self-destruction that involves numerous biomarkers and signaling pathways.
In vitro and in vivo application of glycoalkaloids derivatives α-solamargine and α-solasonine expressed a significant effect in inhibition of tumor formation and growth in fish and mice and human prostate cancer cell lines.
Indeed, in the human prostate cancer cell PC-3. administration of a non-toxic dose of α-solanine initiated cancer suppression and reduced the viability of the human cancer cell through significantly elevated epithelial marker E-cadherin gene expression in target mutated cells in the induction of cell proliferation and invasion and decreased mesenchymal marker vimentin expression in initiated cell metastasis.
Further differentiation, also suggested that α-Solanine ameliorated cancer cell proliferation and tumor initiation through reduced mRNA levels of matrix metalloproteinase-2 (MMP-2) and 9 (MMP-9) in stimulated cancer invasion and metastasis and increased the expression of reversion-inducing cysteine-rich protein with kazal motifs (RECK) in suppression of prostate tumor progression and tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2 in the regulation of MMP activity, particular in the induction of cancer cell overexpression.
According to the observation of the Immunoblotting assays, injection of α-solanine is effective in suppressing phosphorylation of phosphatidylinositide-3 kinase (PI3K) which plays an important role in modulated cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking involved cancer progression, Akt phosphorylates expression with primary functions is to promote cell growth and protein synthesis and The extracellular signal-regulated kinase (ERK) signaling pathway phosphorylates with function in the control of diverse cellular processes including such as proliferation, survival, differentiation, and motility.
Moreover, α-solanine reduced levels of microRNA-21 (miR-21) in the expression of cancer progression. Higher levels of miR-21 are correlated to more advanced malignancies and elevated tumor suppressor miR-138 expression in induced prostate cancer cells apoptosis through cell cycle arrest at G1/S transition.
Taken together, eggplant with abundant phytochemicals including glycoalkaloids derivatives α-solamargine and α-solasonine may be considered as a functional food in reduced risk and treatment of prostate cancer.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes by Friedman M1. (PubMed)
(2) α-Solanine inhibits invasion of human prostate cancer cells by suppressing epithelial-mesenchymal transition and MMPs expression by Shen KH1, Liao AC2, Hung JH3, Lee WJ4, Hu KC5, Lin PT6, Liao RF7, Chen PS8. (PubMed)
#Healthyfood #Onion Inhibits the Risk of Prostate Cancer, According to Studies
By Kyle J. Norton
The prostate warped around a tube (the urethra) is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm. The prostate gland is considered a reproductive organ in men.
Prostate cancer is a medical condition caused by cell growth disorderly in the prostate tissue due to the alternation of DNA.
At the advanced stage, the cancerous cell in the prostate can spread to a distance away to inject other healthy tissue and organ, leading to secondary metastasis through lymph and blood.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to the statistics provided by the American Cancer Society, approximately 174,650 cases of prostate cancer will be diagnosed in 2019. Prostate cancer will cause the death of 31620 Americans.
The exact causes of prostate cancer are not known. However, epidemiologically, below are some of the most prevalent factors associated with prostate cancer risk
*Age
The risk of developing prostate cancer increases with the age of over 45
* Family history
Statistics showed that if one of your directed family members has prostate cancer, you are twice at risk to develop it as well.
*Race
Prostate cancer is more likely to strike black and white or Hispanic men in the US.
* Heredity
The certain gene mutation is associated with promoting prostate cancer growth, including hereditary prostate cancer gene 1 (HPC1), transmembrane protease, serine 2-ERG or transmembrane protease, serine 2-ETV1/4, etc.
Researchers found that up to 70 percent of men with prostate cancer have lost one copy of the Phosphatase and tensin homolog (PTEN) gene at the time of diagnosis. The tumor protein 53
(p53) mutations are a late event in the pathology of prostate cancer.
* Low levels of vitamin D in the blood
Researchers found that men with a deficiency of level of vitamin D in the blood are at higher risk to develop prostate cancer.
* Excessive drinking
Excessive drinking not only increases the risk of liver cancer but is also associated with a higher risk of prostate cancer as it interferes with folate metabolism. The risk of prostate cancer is much high for men with excessive drinking habits and folate deficiency.
* Enlarged prostate
Men with an enlarged prostate are at high risk of developing prostate cancer.
* Sexual transmission diseases
Infected diseases such as chlamydia, gonorrhea, or syphilis are associated with a higher risk of infections.
*Obesity
In a study of Obesity May Raise Risk of Prostate Cancer Spread, Christopher J. Keto, MD, a urological oncology postdoctoral associate at Duke University Medical Center, Durham, N.C. found that overweight men were three times more likely to have their cancer spread.
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
To find a potential compound for the promotion of prostate health, researchers examined the effect of onion on prostate cancer in vivo and in vitro.
According to a population-based case-control study in Shanghai, Hsing et. al. participants in the highest of 3 intake categories of total Allium vegetables, including onion showed a significant effect in reducing the risk of prostate cancer with the relative odds ratio risk of .53 compared to those with the lowest intake.
In the Italian and Swiss case-control networks study, researchers surprisingly showed that participants with the highest intake of both onions do not have significantly decreased OR of prostate cancer compared to those with the lowest intake, However, according to the differentiation, there was evidence of a trend of decreased odds with increasing intake.
In other words, over time, increased intake of onion may have significant activity in reducing prostate cancer risk.
The results strongly suggested, over time, regular consumption may decrease the risk of prostate cancer, depending on the amount of onion intake daily.
Taken altogether, onion used alone or combined with conventional medicine may be considered a remedy for the prevention and treatment of adjuvant rheumatic diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Garlic and onions: Their cancer prevention properties by Holly L. Nicastro,1 Sharon A. Ross,2 and John A. Milner. (PubMed)
(2) Prostate Cancer by Kyle J. Norton
The prostate warped around a tube (the urethra) is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm. The prostate gland is considered a reproductive organ in men.
Prostate cancer is a medical condition caused by cell growth disorderly in the prostate tissue due to the alternation of DNA.
At the advanced stage, the cancerous cell in the prostate can spread to a distance away to inject other healthy tissue and organ, leading to secondary metastasis through lymph and blood.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to the statistics provided by the American Cancer Society, approximately 174,650 cases of prostate cancer will be diagnosed in 2019. Prostate cancer will cause the death of 31620 Americans.
The exact causes of prostate cancer are not known. However, epidemiologically, below are some of the most prevalent factors associated with prostate cancer risk
*Age
The risk of developing prostate cancer increases with the age of over 45
* Family history
Statistics showed that if one of your directed family members has prostate cancer, you are twice at risk to develop it as well.
*Race
Prostate cancer is more likely to strike black and white or Hispanic men in the US.
* Heredity
The certain gene mutation is associated with promoting prostate cancer growth, including hereditary prostate cancer gene 1 (HPC1), transmembrane protease, serine 2-ERG or transmembrane protease, serine 2-ETV1/4, etc.
Researchers found that up to 70 percent of men with prostate cancer have lost one copy of the Phosphatase and tensin homolog (PTEN) gene at the time of diagnosis. The tumor protein 53
(p53) mutations are a late event in the pathology of prostate cancer.
* Low levels of vitamin D in the blood
Researchers found that men with a deficiency of level of vitamin D in the blood are at higher risk to develop prostate cancer.
* Excessive drinking
Excessive drinking not only increases the risk of liver cancer but is also associated with a higher risk of prostate cancer as it interferes with folate metabolism. The risk of prostate cancer is much high for men with excessive drinking habits and folate deficiency.
* Enlarged prostate
Men with an enlarged prostate are at high risk of developing prostate cancer.
* Sexual transmission diseases
Infected diseases such as chlamydia, gonorrhea, or syphilis are associated with a higher risk of infections.
*Obesity
In a study of Obesity May Raise Risk of Prostate Cancer Spread, Christopher J. Keto, MD, a urological oncology postdoctoral associate at Duke University Medical Center, Durham, N.C. found that overweight men were three times more likely to have their cancer spread.
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
To find a potential compound for the promotion of prostate health, researchers examined the effect of onion on prostate cancer in vivo and in vitro.
According to a population-based case-control study in Shanghai, Hsing et. al. participants in the highest of 3 intake categories of total Allium vegetables, including onion showed a significant effect in reducing the risk of prostate cancer with the relative odds ratio risk of .53 compared to those with the lowest intake.
In the Italian and Swiss case-control networks study, researchers surprisingly showed that participants with the highest intake of both onions do not have significantly decreased OR of prostate cancer compared to those with the lowest intake, However, according to the differentiation, there was evidence of a trend of decreased odds with increasing intake.
In other words, over time, increased intake of onion may have significant activity in reducing prostate cancer risk.
The results strongly suggested, over time, regular consumption may decrease the risk of prostate cancer, depending on the amount of onion intake daily.
Taken altogether, onion used alone or combined with conventional medicine may be considered a remedy for the prevention and treatment of adjuvant rheumatic diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Garlic and onions: Their cancer prevention properties by Holly L. Nicastro,1 Sharon A. Ross,2 and John A. Milner. (PubMed)
(2) Prostate Cancer by Kyle J. Norton
#Healthyfood #Beet and #Carrot Protect the LiverTissues by Inhibiting the Liver #OxidativeStress, Researchers Say
By Kyle J. Norton
A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.
Non-alcoholic fatty liver (NAFL) is the early stage of nonalcoholic steatohepatitis (NASH) caused by the accumulation of fat in the liver, other than excessive use of alcohol.
Nonalcoholic steatohepatitis (NASH) is a type of inflammatory non-alcoholic fatty liver disease caused by excessive fat accumulated in the liver.
Nonalcoholic steatohepatitis (NASH) is asymptomatic until the condition is developed into cirrhosis, the condition that causes advanced liver scars and reduced the performance of the liver.
In other words, if more than 5% – 10% percent of your liver’s weight is fat, you have a fatty liver (steatosis).
According to the statistics, non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of liver disease affecting 100 million people in the US. Out of that number, approximately 20% of people have NASH.
Medical conditions such as obesity, metabolic syndrome, and type 2 diabetes are some of the metabolic risk factors that have been found to induce the development of NASH.
As of today, there is no effective treatment for NASH. Depending on the condition people with overweight or obese are recommended to lose weight. The aim of medical treatment is to reduce the symptoms and delay the progression of the condition and improve the quality of life.
Out of many prevalent factors that cause the onset of NASH, some researchers suggested that the promotion of a high-fat diet over the past few decades induced a high percentage of the overweight and obese population may be the major culprit associated with the rise of NASH.
Dr. Jensen VS, the lead scientist wrote, "Hepatic dysfunction and inflammation were confirmed in HFD-fed rats by elevated levels of hepatic MCP-1 (p < 0.0001), TNF-alpha (p < 0.001) and plasma β-hydroxybutyrate (p < 0.0001), and in NASH-fed rats by elevated levels of hepatic MCP-1 (p < 0.01), increased hepatic macrophage infiltration (p < 0.001), and higher plasma levels of alanine aminotransferase (p < 0.0001) aspartate aminotransferase (p < 0.05), haptoglobin (p < 0.001) and TIMP-1 (p < 0.01) compared to Control".
And, " dietary fat and cholesterol are the primary drivers of NAFLD development and progression in rats, while fructose mostly exerts its effect on the circulating lipid pool".
Betaxanthins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
In finding a potent ingredient for the treatment of liver disease, researchers examined the protecting effects of bioactive agents of the lyophilized table beet and carrot powder on fatty liver.
The shortened-term study included male Wistar rats fed with chow with or without high fat (2% cholesterol, 0.5% cholic acid, 20% sunflower oil) and treated with 0.1 or 1 g/bwkg/day natural product for ten days parallel with the feedings.
Based on the tested analysis, compared to other feedings, the higher dose of the natural product better decreased the induced free radical reactions, cyclooxygenase-2, and proteins associated with the production of pro-inflammatory cytokines in normal and fatty liver tissues.
More precisely, the natural treatment of beet and carrot powder inhibited liver oxidative stress by inhibiting the inflammatory expression without causing significant changes in all global antioxidant parameters.
However, the antioxidant activity of mobilized methyl group concentrations associated with liver stress also increased by fatty liver tissues.
Based on the evidence, researchers said, "Beet and carrot proved to be a "functional food" in rats with alimentary fat-induced fatty liver. It cannot be ruled out that this beneficial effect may have clinical relevance".
Taken altogether, beet and carrot may be considered functional remedies for the prevention of fatty liver disease, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Experimental food-induced fatty liver and its adjuvant therapy with natural bioactive substances].
[Article in Hungarian] by Hegedüs V1, Gerö D, Mihály Z, Szijártó A, Zelles T, Sárdi E. (PubMed)
A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.
Non-alcoholic fatty liver (NAFL) is the early stage of nonalcoholic steatohepatitis (NASH) caused by the accumulation of fat in the liver, other than excessive use of alcohol.
Nonalcoholic steatohepatitis (NASH) is a type of inflammatory non-alcoholic fatty liver disease caused by excessive fat accumulated in the liver.
Nonalcoholic steatohepatitis (NASH) is asymptomatic until the condition is developed into cirrhosis, the condition that causes advanced liver scars and reduced the performance of the liver.
In other words, if more than 5% – 10% percent of your liver’s weight is fat, you have a fatty liver (steatosis).
According to the statistics, non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of liver disease affecting 100 million people in the US. Out of that number, approximately 20% of people have NASH.
Medical conditions such as obesity, metabolic syndrome, and type 2 diabetes are some of the metabolic risk factors that have been found to induce the development of NASH.
As of today, there is no effective treatment for NASH. Depending on the condition people with overweight or obese are recommended to lose weight. The aim of medical treatment is to reduce the symptoms and delay the progression of the condition and improve the quality of life.
Out of many prevalent factors that cause the onset of NASH, some researchers suggested that the promotion of a high-fat diet over the past few decades induced a high percentage of the overweight and obese population may be the major culprit associated with the rise of NASH.
Dr. Jensen VS, the lead scientist wrote, "Hepatic dysfunction and inflammation were confirmed in HFD-fed rats by elevated levels of hepatic MCP-1 (p < 0.0001), TNF-alpha (p < 0.001) and plasma β-hydroxybutyrate (p < 0.0001), and in NASH-fed rats by elevated levels of hepatic MCP-1 (p < 0.01), increased hepatic macrophage infiltration (p < 0.001), and higher plasma levels of alanine aminotransferase (p < 0.0001) aspartate aminotransferase (p < 0.05), haptoglobin (p < 0.001) and TIMP-1 (p < 0.01) compared to Control".
And, " dietary fat and cholesterol are the primary drivers of NAFLD development and progression in rats, while fructose mostly exerts its effect on the circulating lipid pool".
Betaxanthins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
In finding a potent ingredient for the treatment of liver disease, researchers examined the protecting effects of bioactive agents of the lyophilized table beet and carrot powder on fatty liver.
The shortened-term study included male Wistar rats fed with chow with or without high fat (2% cholesterol, 0.5% cholic acid, 20% sunflower oil) and treated with 0.1 or 1 g/bwkg/day natural product for ten days parallel with the feedings.
Based on the tested analysis, compared to other feedings, the higher dose of the natural product better decreased the induced free radical reactions, cyclooxygenase-2, and proteins associated with the production of pro-inflammatory cytokines in normal and fatty liver tissues.
More precisely, the natural treatment of beet and carrot powder inhibited liver oxidative stress by inhibiting the inflammatory expression without causing significant changes in all global antioxidant parameters.
However, the antioxidant activity of mobilized methyl group concentrations associated with liver stress also increased by fatty liver tissues.
Based on the evidence, researchers said, "Beet and carrot proved to be a "functional food" in rats with alimentary fat-induced fatty liver. It cannot be ruled out that this beneficial effect may have clinical relevance".
Taken altogether, beet and carrot may be considered functional remedies for the prevention of fatty liver disease, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Experimental food-induced fatty liver and its adjuvant therapy with natural bioactive substances].
[Article in Hungarian] by Hegedüs V1, Gerö D, Mihály Z, Szijártó A, Zelles T, Sárdi E. (PubMed)
#Healthyfood #NavyBean Inhibits the Risk of #ColonCancer in Vivo, Researchers Say
By Kyle J. Norton
Cancer is a class of diseases associated with irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
Compared to normal cells with a limited cell cycle division before replacing by a set of new cells, malignant cells have an unlimited cycle division. In other words, cancerous cells ignore cell division inhibitors.
Primary colon cancer is a medical condition caused by abnormal cell growth in the colon tissue. Most cases of colon cancer begin on the surface of the inner lining tissue of the colon, before penetrating into deeper layers to form a tumor through proliferation.
At the advanced stage, the cancerous cells can dispatch from the original site to infect other healthy tissue and organs far away from the colon, leading to secondary metastasis.
The exact causes of colon cancer are unknown. researchers do not know why people with the same health condition, family history, and diet, are susceptible to the onset of the disease while others do not.
According to the statistic, colorectal cancer(cancer that starts in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
The Colorectal Cancer Alliance suggested, on average, the lifetime risk of developing colon cancer is about one in 23 for men and women combined (4.5%), however, this varies widely according to individual risk factors.
Out of many risk factors associated with the onset of colon cancer, some researchers suggested that the risk of colon cancer may have a direct implication from the promotion of a high-fat diet over the past few decades
Dr. Milly Ryan-Harshman wrote, "Whether red meat is a culprit in causing CRC remains unanswered, although any effect it might have is likely moderate and related to processing or cooking"
And "The effect of dietary fiber on the risk of CRC has also been difficult to determine because fiber intake is generally low. Evidence that folic acid, calcium, and vitamin D reduce the risk of CRC is stronger"
These results strongly suggested that by reducing the intake of red meat and processed foods, and increasing the intake of nutrients from fruits and vegetables including folic calcium and vitamin D, the risk of colorectal cancer can be substantially decreased.
However, in the study conducted by the team led by Dr. Dana-Farber, Cancer Center oncologist Jeffrey Meyerhardt, MD appeared in the Aug. 15 issue of the Journal of the American Medical Association, the Western diet not only associated with the colon cancer risk but also elevate the risk of recurrent colon cancer in colon cancer patients.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a natural and dietary compound for the treatment of colon cancer, researchers examined the effects of navy beans on mice-induced colon cancer.
The study included cooked navy beans (whole beans), the insoluble fraction (bean residue) or soluble fraction of the 60% (vol: vol) ethanol extract of cooked navy beans (bean extract), or a modified AIN-93G diet (16.6% fat including 12.9% lard) as control fed to 160 male obese ob/ob mice after 2 azoxymethane injections.
According to the tested assays mice fed with navy beans showed a reduction of dysplasia, adenomas, or adenocarcinomas in fewer mice compared to control.
More precisely, whole beans 54%, P=0.10; bean residue 81%, P=0.003; bean extract 91%, P=0.007), inhibited all types of colon lesions, including focal hyperplasia compared to control.
Based on the findings researchers wrote, "suggest that both the soluble and the insoluble fraction of the extract contribute to the cancer-protective effect of cooked navy beans".
In order to reveal additional information about navy bean anti-colon cancer activity, researchers evaluated whether black beans and/or navy beans would reduce colon carcinogenesis in rats.
The study included rats fed a modified AIN-93G diet (control) or diets containing 75% black beans or 75% navy beans for 4 wk before colon cancer was initiated by the administration of two injections of azoxymethane 1 wk apart.
At 31 wk after the second injection, the incidence of colon adenocarcinomas was significantly lower in navy bean (14%) diets compared to rats fed the black bean (9%) diets and control diet (36%).
Furthermore, total tumor multiplicity was also significantly lower in rats fed the navy bean (1.0) diets compared to the black bean (1.1) and control diet (2.2).
Based on the additional analysis, researchers found that the 44-75% reduction in colon carcinogenesis in rats fed beans was attributed to more controlled appetites and much greater concentrations of butyrate in the distal colon.
The results strongly suggested eating....navy beans significantly lowered colon cancer incidence and multiplicity.
Taken altogether, the navy bean may be considered a remedy for the prevention and treatment of colon cancer, pending the confirmation of the larger sample size and multicenter human study. larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice by Bobe G1, Barrett KG, Mentor-Marcel RA, Saffiotti U, Young MR, Colburn NH, Albert PS, Bennink MR, Lanza E. (PubMed)
(2) Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats by Hangen L1, Bennink MR. (PubMed)
(3) Diet and colorectal cancer, Review of the evidence by Milly Ryan-Harshman, Ph.D. RD. (PubMed)
Cancer is a class of diseases associated with irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
Compared to normal cells with a limited cell cycle division before replacing by a set of new cells, malignant cells have an unlimited cycle division. In other words, cancerous cells ignore cell division inhibitors.
Primary colon cancer is a medical condition caused by abnormal cell growth in the colon tissue. Most cases of colon cancer begin on the surface of the inner lining tissue of the colon, before penetrating into deeper layers to form a tumor through proliferation.
At the advanced stage, the cancerous cells can dispatch from the original site to infect other healthy tissue and organs far away from the colon, leading to secondary metastasis.
The exact causes of colon cancer are unknown. researchers do not know why people with the same health condition, family history, and diet, are susceptible to the onset of the disease while others do not.
According to the statistic, colorectal cancer(cancer that starts in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
The Colorectal Cancer Alliance suggested, on average, the lifetime risk of developing colon cancer is about one in 23 for men and women combined (4.5%), however, this varies widely according to individual risk factors.
Out of many risk factors associated with the onset of colon cancer, some researchers suggested that the risk of colon cancer may have a direct implication from the promotion of a high-fat diet over the past few decades
Dr. Milly Ryan-Harshman wrote, "Whether red meat is a culprit in causing CRC remains unanswered, although any effect it might have is likely moderate and related to processing or cooking"
And "The effect of dietary fiber on the risk of CRC has also been difficult to determine because fiber intake is generally low. Evidence that folic acid, calcium, and vitamin D reduce the risk of CRC is stronger"
These results strongly suggested that by reducing the intake of red meat and processed foods, and increasing the intake of nutrients from fruits and vegetables including folic calcium and vitamin D, the risk of colorectal cancer can be substantially decreased.
However, in the study conducted by the team led by Dr. Dana-Farber, Cancer Center oncologist Jeffrey Meyerhardt, MD appeared in the Aug. 15 issue of the Journal of the American Medical Association, the Western diet not only associated with the colon cancer risk but also elevate the risk of recurrent colon cancer in colon cancer patients.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a natural and dietary compound for the treatment of colon cancer, researchers examined the effects of navy beans on mice-induced colon cancer.
The study included cooked navy beans (whole beans), the insoluble fraction (bean residue) or soluble fraction of the 60% (vol: vol) ethanol extract of cooked navy beans (bean extract), or a modified AIN-93G diet (16.6% fat including 12.9% lard) as control fed to 160 male obese ob/ob mice after 2 azoxymethane injections.
According to the tested assays mice fed with navy beans showed a reduction of dysplasia, adenomas, or adenocarcinomas in fewer mice compared to control.
More precisely, whole beans 54%, P=0.10; bean residue 81%, P=0.003; bean extract 91%, P=0.007), inhibited all types of colon lesions, including focal hyperplasia compared to control.
Based on the findings researchers wrote, "suggest that both the soluble and the insoluble fraction of the extract contribute to the cancer-protective effect of cooked navy beans".
In order to reveal additional information about navy bean anti-colon cancer activity, researchers evaluated whether black beans and/or navy beans would reduce colon carcinogenesis in rats.
The study included rats fed a modified AIN-93G diet (control) or diets containing 75% black beans or 75% navy beans for 4 wk before colon cancer was initiated by the administration of two injections of azoxymethane 1 wk apart.
At 31 wk after the second injection, the incidence of colon adenocarcinomas was significantly lower in navy bean (14%) diets compared to rats fed the black bean (9%) diets and control diet (36%).
Furthermore, total tumor multiplicity was also significantly lower in rats fed the navy bean (1.0) diets compared to the black bean (1.1) and control diet (2.2).
Based on the additional analysis, researchers found that the 44-75% reduction in colon carcinogenesis in rats fed beans was attributed to more controlled appetites and much greater concentrations of butyrate in the distal colon.
The results strongly suggested eating....navy beans significantly lowered colon cancer incidence and multiplicity.
Taken altogether, the navy bean may be considered a remedy for the prevention and treatment of colon cancer, pending the confirmation of the larger sample size and multicenter human study. larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice by Bobe G1, Barrett KG, Mentor-Marcel RA, Saffiotti U, Young MR, Colburn NH, Albert PS, Bennink MR, Lanza E. (PubMed)
(2) Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats by Hangen L1, Bennink MR. (PubMed)
(3) Diet and colorectal cancer, Review of the evidence by Milly Ryan-Harshman, Ph.D. RD. (PubMed)
#Healthyfood #BeetRoot In the Inhibition of the Diseases Associated with Over Expression of #OxidativeStress, Scientists Say
By Kyle J. Norton
Beet may have a potential effect as antioxidants in reduced free radical and oxidative stress expression through its chemical constituents, some scientists suggested
Antioxidants are a set of substances with inhibited oxidative function
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the joint study led by the Istanbul Technical University, fresh red beetroot and beetroots products contain several major antioxidants with efficacy different, depending on total antioxidant capacities (TAC)(total phenolic (TP) and total flavonoid (TF) contents and individual).
In Lactobacillus paracasei 0920 (FBJ) on carcinogen induction of aberrant crypt foci (ACF), the abnormal tube-like glands in the lining of the colon and rectum in rat colon by 2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) administrated intragastrically at a dose of 10 μg/day, every day of the experiment, rats fed with beetroot juice showed a significant improvement of cytotoxic and genotoxic effects through increased the antioxidant status of serum from 40% to 66% depending on the fraction.
In other words, oxidative stress-induced production of toxins and toxic chemical agents which may alternate DNA transcript were inhibited by phytochemicals in beet juice.
2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a toxic chemical formed in condensation of creatinine found in muscle meats, with amino acids in high temperature,
Interestingly, the formation of pro-oxidative stress found in the blood of colorectal carcinoma patients. was associated with decreased concentration of antioxidant status together with a lower amount of uric acid in the expression of antioxidants which was found to have a potential effect
in the treatment of diseases associated with oxidative stress.
Furthermore, levels of oxidative stress are also found in the measurement of serum antioxidant status and the level of malondialdehyde, a marker of oxidative stress in the rat's kidneys and liver.
Additionally, in a male Wistar rat model of oxidative stress induced by N-nitrosodiethylamine (NDEA) and carbon tetrachloride (CCl(4)), the group fed with beetroot juice per os, 8 mL/kg/day for 28 days, and a single i.p. the dose of the xenobiotics: 150 mg/kg NDEA or 2 mL/kg CCl(4) and xenobiotics the only group, the treatment group showed a partial recovery in the activity of glutathione peroxidase and glutathione reductase, by 35% and 66%, respectively.
Glutathione peroxidase (GPx) with peroxidase activity is an antioxidant with a function to protect the organism from oxidative damage.
The activity of glutathione reductase is a cellular antioxidant with a function to protect the organism against xenobiotics.
Particularly, the levels of Superoxide dismutase activity against the oxidative stress-induced formation of inflammation also increased by 3-fold compared to the non-juice treatment group.
Importantly, the treatment group also showed significant inhibition of oxidative stress in protected DNA damage caused by N-nitroso diethylamine (NDEA) and carbon tetrachloride (CCl(4)) by 20%.
These findings showed a remarkable efficacy of beet juice and products in ameliorating free radicals and pro-inflammatory expression through elevated antioxidant status which warrant a human trial for validity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Home-Processed Red Beetroot (Beta vulgaris L.) Products: Changes in Antioxidant Properties and Bioaccessibility by Guldiken B1, Toydemir G2, Nur Memis K3, Okur S4, Boyacioglu D5, Capanoglu E6.(PubMed)
(2) Protective effect of lactofermented red beetroot juice against aberrant crypt foci formation, genotoxicity of fecal water and oxidative stress induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats modelm by Klewicka E1, Nowak A, Zduńczyk Z, Juśkiewicz J, Cukrowska B.(PubMed)
Beet may have a potential effect as antioxidants in reduced free radical and oxidative stress expression through its chemical constituents, some scientists suggested
Antioxidants are a set of substances with inhibited oxidative function
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the joint study led by the Istanbul Technical University, fresh red beetroot and beetroots products contain several major antioxidants with efficacy different, depending on total antioxidant capacities (TAC)(total phenolic (TP) and total flavonoid (TF) contents and individual).
In Lactobacillus paracasei 0920 (FBJ) on carcinogen induction of aberrant crypt foci (ACF), the abnormal tube-like glands in the lining of the colon and rectum in rat colon by 2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) administrated intragastrically at a dose of 10 μg/day, every day of the experiment, rats fed with beetroot juice showed a significant improvement of cytotoxic and genotoxic effects through increased the antioxidant status of serum from 40% to 66% depending on the fraction.
In other words, oxidative stress-induced production of toxins and toxic chemical agents which may alternate DNA transcript were inhibited by phytochemicals in beet juice.
2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a toxic chemical formed in condensation of creatinine found in muscle meats, with amino acids in high temperature,
Interestingly, the formation of pro-oxidative stress found in the blood of colorectal carcinoma patients. was associated with decreased concentration of antioxidant status together with a lower amount of uric acid in the expression of antioxidants which was found to have a potential effect
in the treatment of diseases associated with oxidative stress.
Furthermore, levels of oxidative stress are also found in the measurement of serum antioxidant status and the level of malondialdehyde, a marker of oxidative stress in the rat's kidneys and liver.
Additionally, in a male Wistar rat model of oxidative stress induced by N-nitrosodiethylamine (NDEA) and carbon tetrachloride (CCl(4)), the group fed with beetroot juice per os, 8 mL/kg/day for 28 days, and a single i.p. the dose of the xenobiotics: 150 mg/kg NDEA or 2 mL/kg CCl(4) and xenobiotics the only group, the treatment group showed a partial recovery in the activity of glutathione peroxidase and glutathione reductase, by 35% and 66%, respectively.
Glutathione peroxidase (GPx) with peroxidase activity is an antioxidant with a function to protect the organism from oxidative damage.
The activity of glutathione reductase is a cellular antioxidant with a function to protect the organism against xenobiotics.
Particularly, the levels of Superoxide dismutase activity against the oxidative stress-induced formation of inflammation also increased by 3-fold compared to the non-juice treatment group.
Importantly, the treatment group also showed significant inhibition of oxidative stress in protected DNA damage caused by N-nitroso diethylamine (NDEA) and carbon tetrachloride (CCl(4)) by 20%.
These findings showed a remarkable efficacy of beet juice and products in ameliorating free radicals and pro-inflammatory expression through elevated antioxidant status which warrant a human trial for validity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Home-Processed Red Beetroot (Beta vulgaris L.) Products: Changes in Antioxidant Properties and Bioaccessibility by Guldiken B1, Toydemir G2, Nur Memis K3, Okur S4, Boyacioglu D5, Capanoglu E6.(PubMed)
(2) Protective effect of lactofermented red beetroot juice against aberrant crypt foci formation, genotoxicity of fecal water and oxidative stress induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats modelm by Klewicka E1, Nowak A, Zduńczyk Z, Juśkiewicz J, Cukrowska B.(PubMed)
#BlackBean Extracts In Reducing the Risk of Hyperglycemia, Researchers Show
By Kyle J. Norton
Hyperglycemia is a condition of abnormally high blood glucose present in the bloodstream.
Black beans, small roughly ovoid legumes with glossy black shells, genus Phaseolus, and belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that the black bean was the first domesticated growth in South America.
Black or common beans with abundant fiber may be considered as functional foods in reduced risk of hyperglycemia, the early onset of diabetes, a renowned institute postulated.
In high-fat diet-induced glucose-intolerant obese C57BL/6J mice, black adzuki bean (BAB) extract injection showed an improved function of pancreatic β cells in inhibiting tolerance of the high glucose-induced glucotoxicity at a concentration of 0.2 mg/mL.
The dietary supplementation BAB extract also expressed significantly (P < .05) improved hyperglycemia and homeostasis model, using an insulin resistance index (HOMA-IR).
Furthermore, mice fed with the extract also stimulated gene expression in regulated glucose metabolism and insulin response.
Dr. Kim M, the lead researcher said, "BAB extract ameliorates hyperglycemia and glucose intolerance, and lowers HOMA-IR (assessment) by regulating insulin secretion and response, and by maintaining the integrity of pancreatic β cells exposed to hyperglycemic conditions".
Additionally, in the investigated possible protective effects of black bean peel extract (BBPE), pomegranate peel extract (PPE), and a combination of the two (PPE + BBPE) on streptozotocin-induced DM mice, researchers at the Xuzhou Medical College, indicated that black bean fed mice showed different degrees, in decreased blood glucose, increased insulin secretion, pancreas weight index, and antioxidative activity.
Dr. Wang JY, the lead author said, "PPE and BBPE, particularly the combination of the two, have the ability to ameliorate hyperglycemia by inhibiting oxidative stress-induced pancreatic damage".
The results of these experiments not only displayed the positive effects of black beans in reduced hyperglycemia risk regardless of types of preparation but also addressed the important issue of the contribution of higher outcomes in risk control.
Promisingly, in the compared glycemic response of bean and rice in traditional meals and rice alone in adults with type 2 diabetes of 17 men and women, group injection of traditional meals showed lower postprandial net glucose values in contrast to the rice control at 90, 120 and 150 minutes.
Collectively, the black bean may be used as a functional food in ameliorating the risk and treatment of hyperglycemia, thus reducing the risk of early onset of diabetes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Black Adzuki Bean (Vigna angularis) Extract Protects Pancreatic β Cells and Improves Glucose Tolerance in C57BL/6J Mice Fed a High-Fat Diet by Kim M1, Kim DK2, Cha YS1.(PubMed)
(2) Extracts of black bean peel and pomegranate peel ameliorate oxidative stress-induced hyperglycemia in mice by Wang JY1, Zhu C1, Qian TW1, Guo H1, Wang DD1, Zhang F1, Yin X1.(PubMed)
(3) Bean and rice meals reduce postprandial glycemic response in adults with type 2 diabetes: a cross-over study by Thompson SV1, Winham DM, Hutchins AM.(PubMed)
Hyperglycemia is a condition of abnormally high blood glucose present in the bloodstream.
Black beans, small roughly ovoid legumes with glossy black shells, genus Phaseolus, and belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that the black bean was the first domesticated growth in South America.
Black or common beans with abundant fiber may be considered as functional foods in reduced risk of hyperglycemia, the early onset of diabetes, a renowned institute postulated.
In high-fat diet-induced glucose-intolerant obese C57BL/6J mice, black adzuki bean (BAB) extract injection showed an improved function of pancreatic β cells in inhibiting tolerance of the high glucose-induced glucotoxicity at a concentration of 0.2 mg/mL.
The dietary supplementation BAB extract also expressed significantly (P < .05) improved hyperglycemia and homeostasis model, using an insulin resistance index (HOMA-IR).
Furthermore, mice fed with the extract also stimulated gene expression in regulated glucose metabolism and insulin response.
Dr. Kim M, the lead researcher said, "BAB extract ameliorates hyperglycemia and glucose intolerance, and lowers HOMA-IR (assessment) by regulating insulin secretion and response, and by maintaining the integrity of pancreatic β cells exposed to hyperglycemic conditions".
Additionally, in the investigated possible protective effects of black bean peel extract (BBPE), pomegranate peel extract (PPE), and a combination of the two (PPE + BBPE) on streptozotocin-induced DM mice, researchers at the Xuzhou Medical College, indicated that black bean fed mice showed different degrees, in decreased blood glucose, increased insulin secretion, pancreas weight index, and antioxidative activity.
Dr. Wang JY, the lead author said, "PPE and BBPE, particularly the combination of the two, have the ability to ameliorate hyperglycemia by inhibiting oxidative stress-induced pancreatic damage".
The results of these experiments not only displayed the positive effects of black beans in reduced hyperglycemia risk regardless of types of preparation but also addressed the important issue of the contribution of higher outcomes in risk control.
Promisingly, in the compared glycemic response of bean and rice in traditional meals and rice alone in adults with type 2 diabetes of 17 men and women, group injection of traditional meals showed lower postprandial net glucose values in contrast to the rice control at 90, 120 and 150 minutes.
Collectively, the black bean may be used as a functional food in ameliorating the risk and treatment of hyperglycemia, thus reducing the risk of early onset of diabetes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Black Adzuki Bean (Vigna angularis) Extract Protects Pancreatic β Cells and Improves Glucose Tolerance in C57BL/6J Mice Fed a High-Fat Diet by Kim M1, Kim DK2, Cha YS1.(PubMed)
(2) Extracts of black bean peel and pomegranate peel ameliorate oxidative stress-induced hyperglycemia in mice by Wang JY1, Zhu C1, Qian TW1, Guo H1, Wang DD1, Zhang F1, Yin X1.(PubMed)
(3) Bean and rice meals reduce postprandial glycemic response in adults with type 2 diabetes: a cross-over study by Thompson SV1, Winham DM, Hutchins AM.(PubMed)
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