#Herbal #Turmeric Improves the Immune Functioning Against the Risk of #AcquiredImmunodeficiencySyndrome (#AIDS), According to Scientists)

By Kyle J. Norton

Acquired immunodeficiency syndrome (AIDS) is a disease associated with human immunodeficiency virus (HIV) infection at the most advanced stage.

In other words, if an HIV-infected person has a CD4, the glycoprotein found on the surface of immune cells counts less than 200 cells/mm3, he/she is considered to have developed AIDS.

AIDS is caused by the infection of HIV. However, most HIV-infected patients are HIV carriers.

The most common risk factors associated with HIV injection are contact with body fluids such as infected blood, milk coming from a mother who carries the HIV, vaginal or anal sex, sharing drugs needles, and oral sex.

Believe it or not, HIV cannot live outside the human body for long because the virus needs body fluid to survive.

According to the statistics, approximately, 1.1 million people in the US are living with HIV, including 15% of those who don't know they are infected. Only half of the patients half are virally suppressed.

In 2016, 39,782 cases of new HIV were diagnosed.

Some researchers' sexual behavior of a person may have a strong impact on increasing the risk of HIV injection. More precisely,

Dr. Molly S. Rosenberg, the lead scientist wrote, "HIV prevalence was very high among HAALSI participants (23%, 95% confidence interval [CI]: 21 to 24), with no sex differences. Recent sexual activity was common (56%, 95% CI: 55 to 58) across all HIV status categories. Condom use was low among HIV-negative adults (15%, 95% CI: 14 to 17), higher among HIV-positive adults who were unaware of their HIV status (27%, 95% CI: 22 to 33), and dramatically higher among HIV-positive adults who were aware of their status (75%, 95% CI: 70 to 80). Casual sex and multiple partnerships were reported at moderate levels, with slightly higher estimates among HIV-positive compared to HIV-negative adults".

And, "Older HIV-positive adults in an HIV hyperendemic community of rural South Africa report sexual behaviors consistent with high HIV transmission risk. Older HIV-negative adults report sexual behaviors consistent with high HIV acquisition risk".

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, and wound healing agent, and for the treatment of treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a natural compound for the treatment of acquired immunodeficiency syndrome, researchers examined the immunomodulatory effects of Curcuma longa L., purple sweet potato, and mixtures of the two (CPM) in an animal model.

The study included selected C57BL/6 mice infected with LP-BM5 murine leukemia virus (MuLV), randomly divided into seven groups as follows:
* Normal control,

* Infected control (LP-BM5 MuLV infection),

* Positive control (LP-BM5 MuLV infection+dietary supplement of red ginseng 300 mg/kg body weight),

* The original powder of C. longa L. (C; LP-BM5 MuLV infection+dietary supplement of C 189 mg/kg body weight),

* The original powder of purple sweet potato (P; LP-BM5 MuLV infection+dietary supplement of P 1811 mg/kg body weight), CPM Low (CPL; LP-BM5 MuLV infection+CPM 2 g/kg body weight), and

* CPM High (CPH; LP-BM5 MuLV infection+CPM 5 g/kg body weight). Dietary supplementation lasted for 12 weeks.

According to the tested assays, dietary supplementation of CPM inhibited LP-BM5 MuLV-induced lymphadenopathy, an inflammatory disease of the lymph nodes, and splenomegaly, a condition of abnormal enlargement of the spleen.

Furthermore, CPM also enhanced the immune function in recognizing invasive and foreign viruses, which may weaken the immune system to initiate the onset of infection.

In other words, CPM enhanced the immune function against the progression of MuLV.

More precisely, CPM reduced the decrease in T- and B cell proliferation reduced the population of CD4(+)/CD8(+) T cells, and inhibited the unbalanced production of T helper-1 (Th1)/T helper-2 (Th2) cytokines in LP-BM5 MuLV-infected mice.


Moreover, the immune function also was exhibited by the injection of CPM observed by the supplement immune-modulatory activity, including the inhibition of the reduction of phagocytosis in peritoneal macrophages and decreased serum levels of immunoglobulin A (IgA), immunoglobulin E (IgE), and immunoglobulin G (IgG).

Based on the results, researchers after taking other factors into account wrote, "CPM had a positive effect on immunomodulation in C57BL/6 mice induced by LP-BM5 leukemia retrovirus infection".

Taken altogether, turmeric used alone or combined with other herbal medicines may be considered supplements for the prevention and treatment of acquired immunodeficiency syndrome, pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Effects of Curcuma longa L., Purple Sweet Potato, and Mixtures of the Two on Immunomodulation in C57BL/6J Mice Infected with LP-BM5 Murine Leukemia Retrovirus by Park SJ1, Lee D1, Lee M1, Kwon HO2, Kim H3, Park J4, Jeon W4, Cha M5, Jun S5, Park K5, Lee J. (PubMed)
(2) Immunomodulatory effects of curcumin in allergy by Kurup VP1, Barrios CS. (PubMed)
(3) Sexual Behaviors and HIV Status: A Population-Based Study Among Older Adults in Rural South Africa by Molly S. Rosenberg, MPH, PhD,*† Francesc X. Gómez-Olivé, MSc, MD, PhD,†‡§ Julia K. Rohr, MPH, PhD,† Brian C. Houle, MPH, PhD,‡‖ Chodziwadziwa W. Kabudula, Msc,‡§¶Ryan G. Wagner, MSc, PhD,‡§ Joshua A. Salomon, PhD,# Kathleen Kahn, MD, MPH, PhD,‡§**Lisa F. Berkman, MS, PhD,†‡#††‡‡ Stephen M. Tollman, MD, MPH, PhD,‡§** andTill Bärnighausen, MD, MSc, ScD. (PMC)

#Herbal #Catnips in the Promotion of #PenileErection and #MalesexualDesire, According to Studies

By Kyle J. Norton

Many researchers have raised questions about their's quality and effectiveness, depending too much on geographic differences, time of growth and harvest, etc. I do believe, these questions can only be answered by an experienced herbalist.

Dopamine, a neurotransmitter plays an important role in the brain of the human body, including sexual behavior. Besides the regulation of cognitive, integrative, and reward processes, the organic chemical of catecholamine and phenethylamine also can trigger penile erection and control of sexual function by acting on oxytocinergic neurons.


Dr. Baskerville TA said," Dopamine demonstrates the potential existence of an interaction between central dopamine and hormone in controlling sexual reproduction during penile erection

In fact, the effect of a pro-erectile dose of apomorphine, a mixed dopamine receptor agonist, showed stimulation of dopamine receptors, induced the release of oxytocin in the brain to mediate and reinforce effects of sexual activity in regulating the sexual behavior (e.g., penile erection) with those controlling sexual motivation and sexual arousal.

Catnip may be the next generation of herbal medicine used as dopamine to increase penile erection and improve male sexual behavior.

Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, used in herbal medicine as an insect repellent, and to treat digestive disorders, children's restlessness and nervousness, fevers, colds, and flu, skin irritations stimulate sweating, promote menstruation, etc.

According to Paulista University, male rats of the NC group increased penile erection. facilitate sexual behavior and a decrease in general activity involving dopaminergic systems.

Several studies suggested that dopamine is a neurotransmitter that plays an important role in regulating and controlling penile erection and sexual behavior, but the use of herbal medicine should only be prescribed by herbalists to prevent depression.

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Sources
(1) Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats by Bernardi MM1, Kirsten TB, Lago JH, Giovani TM, Massoco Cde O.(PubMed)
(2) Dopamine and male sexual function by Giuliano F1, Allard J.(PubMed)
(3) Dopamine-oxytocin interactions in penile erection by Baskerville TA1, Allard J, Wayman C, Douglas AJ.(PubMed)

#Healthyfood #NavyBean Processes Antioxidant Activities, Researchers Say

By Kyle J. Norton

Antioxidants are stable atoms that inhibit oxidation induced by free radicals.
Free radicals are highly unstable atoms. Internally, free radicals are produced by our body's cell metabolism. Externally, free radicals can enter our body from the environmental sources, such as the air we breathe, the food we eat, and the water we drink.

In other words, any chemical compounds or molecules which process an oxygen atom can be free radicals in a chemical reaction with other atoms.

According to epidemiological studies, free radicals are dangerous to human health in excessive amounts. Overexpression of free radicals-induced oxidative stress has been found to damage the lipid, and protein and induce the alternation of healthy cell DNA.

Out of all damages caused by the overexpression of free radicals, some researchers suggested that lipid peroxidation induced by free radicals has a strong implication in the pathogenesis of various disorders and diseases.

In a healthy person, antioxidants produced by the body are more than enough to counter the expression of free radicals. However, in people with a weakened immune system, the intake of dietary antioxidants regularly can be helpful.

Oxidative stress can either be caused by the overexpression of free radicals or the depletion of antioxidant enzymes produced by the host.

Some researchers suggested that by balancing the ratio of free radicals and antioxidants in the body, diseases associated with oxidative stress can be preventable.


Dr. Monica H Carlsen wrote, "A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants".

And, "there are several thousand-fold differences in antioxidant content of foods. Spices, herbs, and supplements include the most antioxidant-rich products in our study, some exceptionally high. Berries, fruits, nuts, chocolate, vegetables, and products thereof constitute common foods and beverages with high antioxidant values".

The results strongly suggested that intake of a higher amount of berries, fruits, nuts, chocolate, and vegetables which are antioxidant-rich products can protect us against the risk of diseases associated with oxidative stress.


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. the beans are now grown and consumed across the world, due to their numerous health benefits.

With an aim to find a natural compound for the treatment of diseases associated with oxidative stress, researchers examined the antioxidant effects of a pinto bean, cowpea, baby lima bean, lentil, chickpea, small red bean, red kidney bean, black kidney bean, navy bean, and mung bean extracts.

Navy beans showed significantly lesser antioxidant activity in vitro compared to those lentils with total antioxidant activity (720.68 U/g), and DPPH• scavenging activity (38.5%).


In free radical scavenging activity, navy bean also showed a lesser activity compared to those of black kidney bean (85.68%) and baby lima bean (74.97%) extracts in inhibiting the oxidation of Among the extracts, hydroxyl radicals (•OH).

In the chemical analysis, the total antioxidant activity (r=0.84), DPPH• scavenging activity (r=0.83), and total reducing power (r=0.84) were positively correlated with the total phenolic content which also lower in the navy been compared to those of lentils.

Taken altogether, the navy bean may be considered a natural antioxidant for the treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.


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Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) In vitro antioxidant activity of extracts from common legumes by Zhao Y1, Du SK2, Wang H1, Cai M. (PubMed)
(2) The total antioxidant content of more than 3100 foods, beverages, spices, herbs, and supplements used worldwide by Monica H Carlsen,#1 Bente L Halvorsen,#1 Kari Holte,1 Siv K Bøhn,1 Steinar Dragland,2Laura Sampson,3 Carol Willey,3 Haruki Senoo,4 Yuko Umezono,4 Chiho Sanada,4Ingrid Barikmo,5 Nega Berhe,1 Walter C Willett,3 Katherine M Phillips,6 David R Jacobs, Jr,1,7and Rune Blomhoff. (PMC)

#Herbal #Andrographis in the Promotion of #ImmunomodulatoryActivity, Researchers Find

By Kyle J. Norton

Andrographis paniculata also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, and upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...

Immunomodulatory Activity is the action in regulated immune response or the functioning of the immune system against forming of diseases, including stimulating the production of antibodies and
inhibited white blood cells in induced inflammation,.....

Andrographis processed significant effects in enhanced immune function, through modulation of immune responses, a renowned institute study suggested.

According to the Prin. K. M. Kundnani College of Pharmacy, HN-02, an extract containing a mixture of andrographolides plus 14-deoxy andrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in pure powder forms at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitro experimental models, demonstrated the ability in enhanced immune function by modulation of immune responses altered during antigen interaction, and to reverse the immunosuppression induced by cyclophosphamide (CYP).

Dr. Naik SR, the lead author said, " HN-02 treatment significant increase in total WBC count" and "elevated the depressed hemagglutination antibody (HA) titer and increased the number of plaque-forming cells (PFCs) in the spleen cells of mice".

Other researchers in the evaluation of the immunomodulatory activity of herbal Andrographis indicated that Andrographis paniculata exhibited the effect through gene expression involved in immune cell activation and migration and various inflammatory responses, including wound healing, angiogenesis, and blood pressure modulation.

The study also identified the chemical compound of lipopolysaccharide in Andrographis paniculata as one of the natural and most active immunostimulatory components.

Additionally, the dichloromethane fraction of the methanolic extract of Andrographis paniculata also expressed an impressive inhibition against testing human cancer and immune cells.
At low concentrations, the dichloromethane extracts enhanced immune function, attenuating the proliferation of HT-29 (colon cancer) cells and human peripheral blood lymphocytes (HPBLs).

Furthermore, the study also found, andrographolide, another major compound in Andrographis paniculata exhibited the immune ability to suppress irregular cell growth and cancer activity on diverse cancer cells in different types of human cancers.

Taking all together, there is no doubt, that Andrographis consists of vigorous immunomodulatory activity in regulated immune responses against a procession of irregular cell growth and overreaction of foreign harmful substances, but intake of large amounts should be taken with care.


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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Sources
(1) Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata by Naik SR1, Hule A.(PubMed)
(2) Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals by Denzler KL1, Waters R, Jacobs BL, Rochon Y, Langland JO.(PubMed)
(3) Anticancer and immunostimulatory compounds from Andrographis paniculata by Kumar RA1, Sridevi K, Kumar NV, Nanduri S, Rajagopal S.(PubMed)

#Healthyfood #GreenBeans in the Reducing the Risk of #Leukemia

By Kyle J. Norton

Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system.

Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow, containing two main types of stem cells is the soft tissue inside the hollow center of the major bone, including the spine, pelvis, underarm, and leg. etc. with the main function of generating blood cells.

Believe it or not, the bone marrow produces 200 billion new red blood cells every day, to replace the blood cells that die off, along with white blood cells and platelets.

According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes the death of 68,000 Americans.

Non-Hodgkin's lymphoma is the 7th most common cancer in the U.S.

Acute leukemia is a condition caused by a rapid increase in the number of extremely immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including acute lymphoblastic leukemia (ALL), acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common childhood form of leukemia with about 80% of all cases.

Chronic leukemia is a condition of the slow but still excessive build-up of relatively mature abnormal white blood cells. The condition has a tendency to spread slowly to other parts of the body through the bloodstream and/or lymphatic system, including chronic lymphocytic leukemia (CLL) and chronic myelogenous leukemia (CML).

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 different species, belongs to the family Fabaceae, and is native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.

On finding a potent veggie for the prevention of leukemia, the University of Texas MD Anderson Cancer Center evaluated associations between the consumption of vegetables, fruits, and meats with AML risk among Texas residents.

According to the results from all participants, 323 adult de novo AML cases and 380 frequency-matched controls, demographic and food frequency questionnaires, overall consuming the darkest green vegetables, including green beans significantly decreased AML risk, comapred to significantly increased among greatest consumers of red meat.


Among women, consumption in the highest quartile of dark-green vegetables had a relative odds ratio of 0.28 compared to the lowest quartile.

In other words, the intake of dark-green vegetables such as green beans has reduced the risk of leukemia only in women compared to men in a dose-dependent manner.

Based on the findings, researchers said, " Based on these findings, interventions can be developed to modify intake of specific dietary components to reduce cancer risk".

Taken altogether, dark-green vegetables such as green beans may be used as an adjunct therapy for the prevention of leukemia in women, pending the confirmation of a larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Dietary intake of vegetables, fruits, and meats/beans as potential risk factors of acute myeloid leukemia: a Texas case-control study by Yamamura Y1, Oum R, Gbito KY, Garcia-Manero G, Strom SS. (PubMed)

#Antioxidant #Indicaxanthin Inhibits the Risk of Hypercholesterolemia and Hypercholesterolemic Complications, According to Studies

By Kyle J. Norton

Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.
In other words, the condition is caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).

Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, building strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.

Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.

The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.

According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.

Sadly, only 50% of people with hypercholesterolemia are getting treatment.

Out of many risk factors associated with the risk of hypercholesterolemia, some researchers suggested that widespread obesity due to aging may have a strong impact on the increased incidence in the US.

Dr. Parini P, the lead scientist wrote, "Plasma cholesterol levels increase with age, as does the incidence of coronary heart disease" and "the relative deficiency in growth hormone (GH), which occurs with aging, contributes to the development of the age-related hypercholesterolemia, because GH has beneficial effects on cholesterol metabolism".

However, researchers continued, "Growth hormone (GH), treatment strongly reduced the hypercholesterolemia in 18-month-old animals. We conclude that the age-dependent increase of plasma cholesterol in rats can be reversed by the administration of GH, presumably through the pleiotropic effects of this hormone on lipoprotein metabolism".

In other words, aging in the promotion of hypercholesterolemia-induced complications can be preventable by the regulation of lipoprotein metabolism.

Indicaxanthin is phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.

On finding a potential compound for the improvement of cholesterol file, researchers examined the effect of Indicaxanthin effects on toxic oxysterols in hypercholesterolemia.

Where toxic oxysterols in hypercholesterolemia have been found to cause suicidal death of human erythrocytes or cryptos is associated with red blood cell programmed death.


According to the tested differentiation, indicaxanthin (Ind) from cactus pear fruit, incubated with isolated healthy human erythrocytes exposed to an oxysterol mixture for 48 h in a concentration range (1.0-5.0 μM) prevents membrane phosphatidylserine (PS) externalization and cell shrinkage in a dose-dependent manner.

In other words, indicaxanthin (Ind) protects the PS that regulates the production of thrombin, the central regulatory molecule of blood coagulation caused by overexpression of ROS and depletion of antioxidant enzymes and production of inflammatory cytokine-induced by an oxysterol mixture without affecting the erythrocyte redox environment or other parameters.

In ex vivo, indicaxanthin (Ind) at 5 μm, induced the spiking levels of normal human blood with the oxysterol mixture for 48 h induced eryptosis, by reducing the production of ROS and decreased levels of GSH.

Furthermore, eryptosis, the suicidal erythrocyte death, leads to cell shrinkage and cell membrane scrambling, and red blood cell programmed death to cause vascular tissue injury was inhibited by 5 μm-Ind.

These results suggested that eryptotic erythrocytes that contribute to thrombotic complications in hypercholesterolemia were prevented by the application of indicaxanthin.

Based on the findings, researchers said, "the positive effects of diets containing Ind on erythrocytes in hypercholesterolaemic subjects".

Taken altogether, indicaxanthin may be considered a remedy for the prevention of hypercholesterolemia complications, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Dietary indicaxanthin from cactus pear (Opuntia ficus-indica L. Mill) fruit prevents eryptosis induced by oxysterols in a hypercholesterolemia-relevant proportion and adhesion of human erythrocytes to endothelial cell layers by Tesoriere L1, Attanzio A1, Allegra M1, Livrea MA. (PubMed)
(2) Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats by Parini P1, Angelin B, Rudling M. (PubMed)

#Healthyfood #Ginger in the Expression of #Antibiotic Activity Against #ParasiteInfection, Researchers Say

By Kyle J. Norton

Ginger may be the next pharmaceutical target to identify the natural ingredient or whole food for the treatment of diseases caused by a bacterial infection, some studies found.
Infection is a medical condition caused by bacteria multiplication after entering the body.

During the acute phase of infection before the bacteria enter the body, white blood cells of the systematic immune response to the bodily injury and damage by activating not only the emergency repair system to cover the wound through coagulation but also stimulating the proteins associated with the production of proinflammatory cytokines to kill off the invaded pathogens.

However, in many instances, overproduction of proinflammatory cytokines can cause damage or death of nearby cells, leading to improper healing with the formation of scars.

In fact, failure to switch from the phase of production of proinflammatory cytokines to anti-inflammatory can interrupt the healing process, leading to chronic wounds and inflammation.

Some researchers suggested that the failure of the switches may be caused by the weakened immune system that can not kill off all foreign invaders within 3 to 8 weeks.

Researchers continued, our immune system has evolved over thousands of years with an aim to kill off all stimuli and pathogens within a said of time, otherwise, they will adapt to the change, causing low-grade inflammation that cannot be reversed in many diseases such as type 2 diabetes and RA.

Most cases of acute infection were blocked in the first phase of the immune system response. In other words, the white blood cells won, pathogens were destroyed and the wound started to recover process without interruption.

However, if the pathogens won, after entering the body, they can initiate infection through the stage of incubation where bacteria multiplying in the specific tissues and organs, leading to colonization and in facilitating disease development.

Patients with acute bacterial infection usually recover in a short period of time within 3 weeks.

Severely, if the immune system can not get rid of the invaders in the said time, some bacterial pathogens will establish life-long chronic infections by the persistent establishment after an acute infection period.

Dr. Cierny G 3rd, the lead scientist, at the RE Orthopaedics, said," Failure of an acute inflammatory response to resolve a wound infection heralds a cascade of events that affect the host and pathogens, culminating in a chronic, refractory condition".

"The factors contributing to this outcome include immune compromise of the host, antimicrobial resistance, wound-healing deficiencies, and the adherence of pathogens to themselves and wound surfaces via an impenetrable, resistant biofilm.".

These results firmly suggested that if you have a weakened immune system you have a substantially increased risk of chronic bacterial infection.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

In finding a natural ingredient or whole food for the prevention and treatment of infection with little or no side effects researchers evaluated the effects of ginger against the monogenean parasite Gyrodactylus turnbulli.

The tested ethanolic and aqueous extracts were prepared for freeze-dried ginger.

An increase in extract concentration was associated with reduced time to parasite immobilization.
Injection at concentrations of 5 and 40ppt ethanolic extract induced parasite death at 26.1±0.7 and 4.9±0.3min, respectively. The ethanolic extract was more efficient. At 75 and 200ppt aqueous ginger extract, induced parasites died at 65.6±2.8 and 1.8±0.2min, respectively.

Bathing G. Turnbull-infected fish in the ethanolic ginger extract (i.e. 5 and 7.5ppt for 90 and 30min, respectively) significantly reduced infection prevalence and intensity.

The higher concentration (i.e. 7.5ppt) proved to be effective as those of Praziquantel, the conventional chemical.


Interestingly, oral treatments of G. Turnbull-infected guppies with diets supplemented with 10 and 20% ginger powder also proved to be ineffective in decreasing parasite load.

Furthermore, in schistosome mansonii-infected mice, extract given daily for 45 days beginning at either 2nd day or 45 days post-infection showed a reduction of worm burden and the egg load in the liver and intestine which coincided with the reduction in granuloma diameters.

Ginger extract exerted a potential effect in reducing some inflammatory mediators that play a crucial role in schistosomal liver fibrosis and its complications.

The in-depth analysis also suggested that ginger extract also minimizes the deleterious effects of inflammatory and oxidative stress markers in the tested mice.

Taken altogether, ginger extracts with the abundant bioactive compound may be used for the prevention and treatment of parasite-infected diseases, pending the larger and multi-center human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Efficacy of ginger-based treatments against infection with Gyrodactylus turnbulli in the guppy (Poecilia reticulata (Peters)) by Levy G1, Zilberg D2, Paladini G1, Fridman S. (PubMed)
(2) Efficiency of ginger (Zingbar officinale) against Schistosoma mansoni infectionduring host-parasite association by Aly HF1, Mantawy MM. (PubMed)
(3) Dietary Onion or Ginger Modulates the Stress Response and Susceptibility to Vibrio harveyi JML1 Infection in Brown-marbled Grouper Epinephelus fuscoguttatus Juveniles by Amar EC1, Apines-Amar MJS2, Faisan JP Jr1. (PubMed)
(4) Treatment of chronic infection by Cierny G 3rd1, DiPasquale D. (PubMed)