By Kyle J. Norton
Antioxidants are stable atoms that inhibit oxidation induced by free radicals.
Free radicals are highly unstable atoms. Internally, free radicals are produced by our body's cell metabolism. Externally, free radicals can enter our body from the environmental sources, such as the air we breathe, the food we eat, and the water we drink.
In other words, any chemical compounds or molecules which process an oxygen atom can be free radicals in a chemical reaction with other atoms.
According to epidemiological studies, free radicals are dangerous to human health in excessive amounts. Overexpression of free radicals-induced oxidative stress has been found to damage the lipid, and protein and induce the alternation of healthy cell DNA.
Out of all damages caused by the overexpression of free radicals, some researchers suggested that lipid peroxidation induced by free radicals has a strong implication in the pathogenesis of various disorders and diseases.
In a healthy person, antioxidants produced by the body are more than enough to counter the expression of free radicals. However, in people with a weakened immune system, the intake of dietary antioxidants regularly can be helpful.
Oxidative stress can either be caused by the overexpression of free radicals or the depletion of antioxidant enzymes produced by the host.
Some researchers suggested that by balancing the ratio of free radicals and antioxidants in the body, diseases associated with oxidative stress can be preventable.
Dr. Monica H Carlsen wrote, "A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants".
And, "there are several thousand-fold differences in antioxidant content of foods. Spices, herbs, and supplements include the most antioxidant-rich products in our study, some exceptionally high. Berries, fruits, nuts, chocolate, vegetables, and products thereof constitute common foods and beverages with high antioxidant values".
The results strongly suggested that intake of a higher amount of berries, fruits, nuts, chocolate, and vegetables which are antioxidant-rich products can protect us against the risk of diseases associated with oxidative stress.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. the beans are now grown and consumed across the world, due to their numerous health benefits.
With an aim to find a natural compound for the treatment of diseases associated with oxidative stress, researchers examined the antioxidant effects of a pinto bean, cowpea, baby lima bean, lentil, chickpea, small red bean, red kidney bean, black kidney bean, navy bean, and mung bean extracts.
Navy beans showed significantly lesser antioxidant activity in vitro compared to those lentils with total antioxidant activity (720.68 U/g), and DPPH• scavenging activity (38.5%).
In free radical scavenging activity, navy bean also showed a lesser activity compared to those of black kidney bean (85.68%) and baby lima bean (74.97%) extracts in inhibiting the oxidation of Among the extracts, hydroxyl radicals (•OH).
In the chemical analysis, the total antioxidant activity (r=0.84), DPPH• scavenging activity (r=0.83), and total reducing power (r=0.84) were positively correlated with the total phenolic content which also lower in the navy been compared to those of lentils.
Taken altogether, the navy bean may be considered a natural antioxidant for the treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In vitro antioxidant activity of extracts from common legumes by Zhao Y1, Du SK2, Wang H1, Cai M. (PubMed)
(2) The total antioxidant content of more than 3100 foods, beverages, spices, herbs, and supplements used worldwide by Monica H Carlsen,#1 Bente L Halvorsen,#1 Kari Holte,1 Siv K Bøhn,1 Steinar Dragland,2Laura Sampson,3 Carol Willey,3 Haruki Senoo,4 Yuko Umezono,4 Chiho Sanada,4Ingrid Barikmo,5 Nega Berhe,1 Walter C Willett,3 Katherine M Phillips,6 David R Jacobs, Jr,1,7and Rune Blomhoff. (PMC)
Wednesday, 31 May 2023
Monday, 29 May 2023
#Herbal #Andrographis in the Promotion of #ImmunomodulatoryActivity, Researchers Find
By Kyle J. Norton
Andrographis paniculata also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, and upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...
Immunomodulatory Activity is the action in regulated immune response or the functioning of the immune system against forming of diseases, including stimulating the production of antibodies and
inhibited white blood cells in induced inflammation,.....
Andrographis processed significant effects in enhanced immune function, through modulation of immune responses, a renowned institute study suggested.
According to the Prin. K. M. Kundnani College of Pharmacy, HN-02, an extract containing a mixture of andrographolides plus 14-deoxy andrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in pure powder forms at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitro experimental models, demonstrated the ability in enhanced immune function by modulation of immune responses altered during antigen interaction, and to reverse the immunosuppression induced by cyclophosphamide (CYP).
Dr. Naik SR, the lead author said, " HN-02 treatment significant increase in total WBC count" and "elevated the depressed hemagglutination antibody (HA) titer and increased the number of plaque-forming cells (PFCs) in the spleen cells of mice".
Other researchers in the evaluation of the immunomodulatory activity of herbal Andrographis indicated that Andrographis paniculata exhibited the effect through gene expression involved in immune cell activation and migration and various inflammatory responses, including wound healing, angiogenesis, and blood pressure modulation.
The study also identified the chemical compound of lipopolysaccharide in Andrographis paniculata as one of the natural and most active immunostimulatory components.
Additionally, the dichloromethane fraction of the methanolic extract of Andrographis paniculata also expressed an impressive inhibition against testing human cancer and immune cells.
At low concentrations, the dichloromethane extracts enhanced immune function, attenuating the proliferation of HT-29 (colon cancer) cells and human peripheral blood lymphocytes (HPBLs).
Furthermore, the study also found, andrographolide, another major compound in Andrographis paniculata exhibited the immune ability to suppress irregular cell growth and cancer activity on diverse cancer cells in different types of human cancers.
Taking all together, there is no doubt, that Andrographis consists of vigorous immunomodulatory activity in regulated immune responses against a procession of irregular cell growth and overreaction of foreign harmful substances, but intake of large amounts should be taken with care.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata by Naik SR1, Hule A.(PubMed)
(2) Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals by Denzler KL1, Waters R, Jacobs BL, Rochon Y, Langland JO.(PubMed)
(3) Anticancer and immunostimulatory compounds from Andrographis paniculata by Kumar RA1, Sridevi K, Kumar NV, Nanduri S, Rajagopal S.(PubMed)
Andrographis paniculata also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, and upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...
Immunomodulatory Activity is the action in regulated immune response or the functioning of the immune system against forming of diseases, including stimulating the production of antibodies and
inhibited white blood cells in induced inflammation,.....
Andrographis processed significant effects in enhanced immune function, through modulation of immune responses, a renowned institute study suggested.
According to the Prin. K. M. Kundnani College of Pharmacy, HN-02, an extract containing a mixture of andrographolides plus 14-deoxy andrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in pure powder forms at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitro experimental models, demonstrated the ability in enhanced immune function by modulation of immune responses altered during antigen interaction, and to reverse the immunosuppression induced by cyclophosphamide (CYP).
Dr. Naik SR, the lead author said, " HN-02 treatment significant increase in total WBC count" and "elevated the depressed hemagglutination antibody (HA) titer and increased the number of plaque-forming cells (PFCs) in the spleen cells of mice".
Other researchers in the evaluation of the immunomodulatory activity of herbal Andrographis indicated that Andrographis paniculata exhibited the effect through gene expression involved in immune cell activation and migration and various inflammatory responses, including wound healing, angiogenesis, and blood pressure modulation.
The study also identified the chemical compound of lipopolysaccharide in Andrographis paniculata as one of the natural and most active immunostimulatory components.
Additionally, the dichloromethane fraction of the methanolic extract of Andrographis paniculata also expressed an impressive inhibition against testing human cancer and immune cells.
At low concentrations, the dichloromethane extracts enhanced immune function, attenuating the proliferation of HT-29 (colon cancer) cells and human peripheral blood lymphocytes (HPBLs).
Furthermore, the study also found, andrographolide, another major compound in Andrographis paniculata exhibited the immune ability to suppress irregular cell growth and cancer activity on diverse cancer cells in different types of human cancers.
Taking all together, there is no doubt, that Andrographis consists of vigorous immunomodulatory activity in regulated immune responses against a procession of irregular cell growth and overreaction of foreign harmful substances, but intake of large amounts should be taken with care.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata by Naik SR1, Hule A.(PubMed)
(2) Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals by Denzler KL1, Waters R, Jacobs BL, Rochon Y, Langland JO.(PubMed)
(3) Anticancer and immunostimulatory compounds from Andrographis paniculata by Kumar RA1, Sridevi K, Kumar NV, Nanduri S, Rajagopal S.(PubMed)
#Healthyfood #GreenBeans in the Reducing the Risk of #Leukemia
By Kyle J. Norton
Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system.
Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Bone marrow, containing two main types of stem cells is the soft tissue inside the hollow center of the major bone, including the spine, pelvis, underarm, and leg. etc. with the main function of generating blood cells.
Believe it or not, the bone marrow produces 200 billion new red blood cells every day, to replace the blood cells that die off, along with white blood cells and platelets.
According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes the death of 68,000 Americans.
Non-Hodgkin's lymphoma is the 7th most common cancer in the U.S.
Acute leukemia is a condition caused by a rapid increase in the number of extremely immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including acute lymphoblastic leukemia (ALL), acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).
In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common childhood form of leukemia with about 80% of all cases.
Chronic leukemia is a condition of the slow but still excessive build-up of relatively mature abnormal white blood cells. The condition has a tendency to spread slowly to other parts of the body through the bloodstream and/or lymphatic system, including chronic lymphocytic leukemia (CLL) and chronic myelogenous leukemia (CML).
Green bean is a genus of Phaseolus Sensu Stricto, containing 55 different species, belongs to the family Fabaceae, and is native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.
On finding a potent veggie for the prevention of leukemia, the University of Texas MD Anderson Cancer Center evaluated associations between the consumption of vegetables, fruits, and meats with AML risk among Texas residents.
According to the results from all participants, 323 adult de novo AML cases and 380 frequency-matched controls, demographic and food frequency questionnaires, overall consuming the darkest green vegetables, including green beans significantly decreased AML risk, comapred to significantly increased among greatest consumers of red meat.
Among women, consumption in the highest quartile of dark-green vegetables had a relative odds ratio of 0.28 compared to the lowest quartile.
In other words, the intake of dark-green vegetables such as green beans has reduced the risk of leukemia only in women compared to men in a dose-dependent manner.
Based on the findings, researchers said, " Based on these findings, interventions can be developed to modify intake of specific dietary components to reduce cancer risk".
Taken altogether, dark-green vegetables such as green beans may be used as an adjunct therapy for the prevention of leukemia in women, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary intake of vegetables, fruits, and meats/beans as potential risk factors of acute myeloid leukemia: a Texas case-control study by Yamamura Y1, Oum R, Gbito KY, Garcia-Manero G, Strom SS. (PubMed)
Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system.
Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Bone marrow, containing two main types of stem cells is the soft tissue inside the hollow center of the major bone, including the spine, pelvis, underarm, and leg. etc. with the main function of generating blood cells.
Believe it or not, the bone marrow produces 200 billion new red blood cells every day, to replace the blood cells that die off, along with white blood cells and platelets.
According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes the death of 68,000 Americans.
Non-Hodgkin's lymphoma is the 7th most common cancer in the U.S.
Acute leukemia is a condition caused by a rapid increase in the number of extremely immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including acute lymphoblastic leukemia (ALL), acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).
In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common childhood form of leukemia with about 80% of all cases.
Chronic leukemia is a condition of the slow but still excessive build-up of relatively mature abnormal white blood cells. The condition has a tendency to spread slowly to other parts of the body through the bloodstream and/or lymphatic system, including chronic lymphocytic leukemia (CLL) and chronic myelogenous leukemia (CML).
Green bean is a genus of Phaseolus Sensu Stricto, containing 55 different species, belongs to the family Fabaceae, and is native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.
On finding a potent veggie for the prevention of leukemia, the University of Texas MD Anderson Cancer Center evaluated associations between the consumption of vegetables, fruits, and meats with AML risk among Texas residents.
According to the results from all participants, 323 adult de novo AML cases and 380 frequency-matched controls, demographic and food frequency questionnaires, overall consuming the darkest green vegetables, including green beans significantly decreased AML risk, comapred to significantly increased among greatest consumers of red meat.
Among women, consumption in the highest quartile of dark-green vegetables had a relative odds ratio of 0.28 compared to the lowest quartile.
In other words, the intake of dark-green vegetables such as green beans has reduced the risk of leukemia only in women compared to men in a dose-dependent manner.
Based on the findings, researchers said, " Based on these findings, interventions can be developed to modify intake of specific dietary components to reduce cancer risk".
Taken altogether, dark-green vegetables such as green beans may be used as an adjunct therapy for the prevention of leukemia in women, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary intake of vegetables, fruits, and meats/beans as potential risk factors of acute myeloid leukemia: a Texas case-control study by Yamamura Y1, Oum R, Gbito KY, Garcia-Manero G, Strom SS. (PubMed)
#Antioxidant #Indicaxanthin Inhibits the Risk of Hypercholesterolemia and Hypercholesterolemic Complications, According to Studies
By Kyle J. Norton
Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.
In other words, the condition is caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).
Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, building strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.
Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.
The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.
According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.
Sadly, only 50% of people with hypercholesterolemia are getting treatment.
Out of many risk factors associated with the risk of hypercholesterolemia, some researchers suggested that widespread obesity due to aging may have a strong impact on the increased incidence in the US.
Dr. Parini P, the lead scientist wrote, "Plasma cholesterol levels increase with age, as does the incidence of coronary heart disease" and "the relative deficiency in growth hormone (GH), which occurs with aging, contributes to the development of the age-related hypercholesterolemia, because GH has beneficial effects on cholesterol metabolism".
However, researchers continued, "Growth hormone (GH), treatment strongly reduced the hypercholesterolemia in 18-month-old animals. We conclude that the age-dependent increase of plasma cholesterol in rats can be reversed by the administration of GH, presumably through the pleiotropic effects of this hormone on lipoprotein metabolism".
In other words, aging in the promotion of hypercholesterolemia-induced complications can be preventable by the regulation of lipoprotein metabolism.
Indicaxanthin is phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.
On finding a potential compound for the improvement of cholesterol file, researchers examined the effect of Indicaxanthin effects on toxic oxysterols in hypercholesterolemia.
Where toxic oxysterols in hypercholesterolemia have been found to cause suicidal death of human erythrocytes or cryptos is associated with red blood cell programmed death.
According to the tested differentiation, indicaxanthin (Ind) from cactus pear fruit, incubated with isolated healthy human erythrocytes exposed to an oxysterol mixture for 48 h in a concentration range (1.0-5.0 μM) prevents membrane phosphatidylserine (PS) externalization and cell shrinkage in a dose-dependent manner.
In other words, indicaxanthin (Ind) protects the PS that regulates the production of thrombin, the central regulatory molecule of blood coagulation caused by overexpression of ROS and depletion of antioxidant enzymes and production of inflammatory cytokine-induced by an oxysterol mixture without affecting the erythrocyte redox environment or other parameters.
In ex vivo, indicaxanthin (Ind) at 5 μm, induced the spiking levels of normal human blood with the oxysterol mixture for 48 h induced eryptosis, by reducing the production of ROS and decreased levels of GSH.
Furthermore, eryptosis, the suicidal erythrocyte death, leads to cell shrinkage and cell membrane scrambling, and red blood cell programmed death to cause vascular tissue injury was inhibited by 5 μm-Ind.
These results suggested that eryptotic erythrocytes that contribute to thrombotic complications in hypercholesterolemia were prevented by the application of indicaxanthin.
Based on the findings, researchers said, "the positive effects of diets containing Ind on erythrocytes in hypercholesterolaemic subjects".
Taken altogether, indicaxanthin may be considered a remedy for the prevention of hypercholesterolemia complications, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary indicaxanthin from cactus pear (Opuntia ficus-indica L. Mill) fruit prevents eryptosis induced by oxysterols in a hypercholesterolemia-relevant proportion and adhesion of human erythrocytes to endothelial cell layers by Tesoriere L1, Attanzio A1, Allegra M1, Livrea MA. (PubMed)
(2) Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats by Parini P1, Angelin B, Rudling M. (PubMed)
Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.
In other words, the condition is caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).
Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, building strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.
Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.
The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.
According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.
Sadly, only 50% of people with hypercholesterolemia are getting treatment.
Out of many risk factors associated with the risk of hypercholesterolemia, some researchers suggested that widespread obesity due to aging may have a strong impact on the increased incidence in the US.
Dr. Parini P, the lead scientist wrote, "Plasma cholesterol levels increase with age, as does the incidence of coronary heart disease" and "the relative deficiency in growth hormone (GH), which occurs with aging, contributes to the development of the age-related hypercholesterolemia, because GH has beneficial effects on cholesterol metabolism".
However, researchers continued, "Growth hormone (GH), treatment strongly reduced the hypercholesterolemia in 18-month-old animals. We conclude that the age-dependent increase of plasma cholesterol in rats can be reversed by the administration of GH, presumably through the pleiotropic effects of this hormone on lipoprotein metabolism".
In other words, aging in the promotion of hypercholesterolemia-induced complications can be preventable by the regulation of lipoprotein metabolism.
Indicaxanthin is phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.
On finding a potential compound for the improvement of cholesterol file, researchers examined the effect of Indicaxanthin effects on toxic oxysterols in hypercholesterolemia.
Where toxic oxysterols in hypercholesterolemia have been found to cause suicidal death of human erythrocytes or cryptos is associated with red blood cell programmed death.
According to the tested differentiation, indicaxanthin (Ind) from cactus pear fruit, incubated with isolated healthy human erythrocytes exposed to an oxysterol mixture for 48 h in a concentration range (1.0-5.0 μM) prevents membrane phosphatidylserine (PS) externalization and cell shrinkage in a dose-dependent manner.
In other words, indicaxanthin (Ind) protects the PS that regulates the production of thrombin, the central regulatory molecule of blood coagulation caused by overexpression of ROS and depletion of antioxidant enzymes and production of inflammatory cytokine-induced by an oxysterol mixture without affecting the erythrocyte redox environment or other parameters.
In ex vivo, indicaxanthin (Ind) at 5 μm, induced the spiking levels of normal human blood with the oxysterol mixture for 48 h induced eryptosis, by reducing the production of ROS and decreased levels of GSH.
Furthermore, eryptosis, the suicidal erythrocyte death, leads to cell shrinkage and cell membrane scrambling, and red blood cell programmed death to cause vascular tissue injury was inhibited by 5 μm-Ind.
These results suggested that eryptotic erythrocytes that contribute to thrombotic complications in hypercholesterolemia were prevented by the application of indicaxanthin.
Based on the findings, researchers said, "the positive effects of diets containing Ind on erythrocytes in hypercholesterolaemic subjects".
Taken altogether, indicaxanthin may be considered a remedy for the prevention of hypercholesterolemia complications, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary indicaxanthin from cactus pear (Opuntia ficus-indica L. Mill) fruit prevents eryptosis induced by oxysterols in a hypercholesterolemia-relevant proportion and adhesion of human erythrocytes to endothelial cell layers by Tesoriere L1, Attanzio A1, Allegra M1, Livrea MA. (PubMed)
(2) Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats by Parini P1, Angelin B, Rudling M. (PubMed)
#Healthyfood #Ginger in the Expression of #Antibiotic Activity Against #ParasiteInfection, Researchers Say
By Kyle J. Norton
Ginger may be the next pharmaceutical target to identify the natural ingredient or whole food for the treatment of diseases caused by a bacterial infection, some studies found.
Infection is a medical condition caused by bacteria multiplication after entering the body.
During the acute phase of infection before the bacteria enter the body, white blood cells of the systematic immune response to the bodily injury and damage by activating not only the emergency repair system to cover the wound through coagulation but also stimulating the proteins associated with the production of proinflammatory cytokines to kill off the invaded pathogens.
However, in many instances, overproduction of proinflammatory cytokines can cause damage or death of nearby cells, leading to improper healing with the formation of scars.
In fact, failure to switch from the phase of production of proinflammatory cytokines to anti-inflammatory can interrupt the healing process, leading to chronic wounds and inflammation.
Some researchers suggested that the failure of the switches may be caused by the weakened immune system that can not kill off all foreign invaders within 3 to 8 weeks.
Researchers continued, our immune system has evolved over thousands of years with an aim to kill off all stimuli and pathogens within a said of time, otherwise, they will adapt to the change, causing low-grade inflammation that cannot be reversed in many diseases such as type 2 diabetes and RA.
Most cases of acute infection were blocked in the first phase of the immune system response. In other words, the white blood cells won, pathogens were destroyed and the wound started to recover process without interruption.
However, if the pathogens won, after entering the body, they can initiate infection through the stage of incubation where bacteria multiplying in the specific tissues and organs, leading to colonization and in facilitating disease development.
Patients with acute bacterial infection usually recover in a short period of time within 3 weeks.
Severely, if the immune system can not get rid of the invaders in the said time, some bacterial pathogens will establish life-long chronic infections by the persistent establishment after an acute infection period.
Dr. Cierny G 3rd, the lead scientist, at the RE Orthopaedics, said," Failure of an acute inflammatory response to resolve a wound infection heralds a cascade of events that affect the host and pathogens, culminating in a chronic, refractory condition".
"The factors contributing to this outcome include immune compromise of the host, antimicrobial resistance, wound-healing deficiencies, and the adherence of pathogens to themselves and wound surfaces via an impenetrable, resistant biofilm.".
These results firmly suggested that if you have a weakened immune system you have a substantially increased risk of chronic bacterial infection.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In finding a natural ingredient or whole food for the prevention and treatment of infection with little or no side effects researchers evaluated the effects of ginger against the monogenean parasite Gyrodactylus turnbulli.
The tested ethanolic and aqueous extracts were prepared for freeze-dried ginger.
An increase in extract concentration was associated with reduced time to parasite immobilization.
Injection at concentrations of 5 and 40ppt ethanolic extract induced parasite death at 26.1±0.7 and 4.9±0.3min, respectively. The ethanolic extract was more efficient. At 75 and 200ppt aqueous ginger extract, induced parasites died at 65.6±2.8 and 1.8±0.2min, respectively.
Bathing G. Turnbull-infected fish in the ethanolic ginger extract (i.e. 5 and 7.5ppt for 90 and 30min, respectively) significantly reduced infection prevalence and intensity.
The higher concentration (i.e. 7.5ppt) proved to be effective as those of Praziquantel, the conventional chemical.
Interestingly, oral treatments of G. Turnbull-infected guppies with diets supplemented with 10 and 20% ginger powder also proved to be ineffective in decreasing parasite load.
Furthermore, in schistosome mansonii-infected mice, extract given daily for 45 days beginning at either 2nd day or 45 days post-infection showed a reduction of worm burden and the egg load in the liver and intestine which coincided with the reduction in granuloma diameters.
Ginger extract exerted a potential effect in reducing some inflammatory mediators that play a crucial role in schistosomal liver fibrosis and its complications.
The in-depth analysis also suggested that ginger extract also minimizes the deleterious effects of inflammatory and oxidative stress markers in the tested mice.
Taken altogether, ginger extracts with the abundant bioactive compound may be used for the prevention and treatment of parasite-infected diseases, pending the larger and multi-center human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Efficacy of ginger-based treatments against infection with Gyrodactylus turnbulli in the guppy (Poecilia reticulata (Peters)) by Levy G1, Zilberg D2, Paladini G1, Fridman S. (PubMed)
(2) Efficiency of ginger (Zingbar officinale) against Schistosoma mansoni infectionduring host-parasite association by Aly HF1, Mantawy MM. (PubMed)
(3) Dietary Onion or Ginger Modulates the Stress Response and Susceptibility to Vibrio harveyi JML1 Infection in Brown-marbled Grouper Epinephelus fuscoguttatus Juveniles by Amar EC1, Apines-Amar MJS2, Faisan JP Jr1. (PubMed)
(4) Treatment of chronic infection by Cierny G 3rd1, DiPasquale D. (PubMed)
Ginger may be the next pharmaceutical target to identify the natural ingredient or whole food for the treatment of diseases caused by a bacterial infection, some studies found.
Infection is a medical condition caused by bacteria multiplication after entering the body.
During the acute phase of infection before the bacteria enter the body, white blood cells of the systematic immune response to the bodily injury and damage by activating not only the emergency repair system to cover the wound through coagulation but also stimulating the proteins associated with the production of proinflammatory cytokines to kill off the invaded pathogens.
However, in many instances, overproduction of proinflammatory cytokines can cause damage or death of nearby cells, leading to improper healing with the formation of scars.
In fact, failure to switch from the phase of production of proinflammatory cytokines to anti-inflammatory can interrupt the healing process, leading to chronic wounds and inflammation.
Some researchers suggested that the failure of the switches may be caused by the weakened immune system that can not kill off all foreign invaders within 3 to 8 weeks.
Researchers continued, our immune system has evolved over thousands of years with an aim to kill off all stimuli and pathogens within a said of time, otherwise, they will adapt to the change, causing low-grade inflammation that cannot be reversed in many diseases such as type 2 diabetes and RA.
Most cases of acute infection were blocked in the first phase of the immune system response. In other words, the white blood cells won, pathogens were destroyed and the wound started to recover process without interruption.
However, if the pathogens won, after entering the body, they can initiate infection through the stage of incubation where bacteria multiplying in the specific tissues and organs, leading to colonization and in facilitating disease development.
Patients with acute bacterial infection usually recover in a short period of time within 3 weeks.
Severely, if the immune system can not get rid of the invaders in the said time, some bacterial pathogens will establish life-long chronic infections by the persistent establishment after an acute infection period.
Dr. Cierny G 3rd, the lead scientist, at the RE Orthopaedics, said," Failure of an acute inflammatory response to resolve a wound infection heralds a cascade of events that affect the host and pathogens, culminating in a chronic, refractory condition".
"The factors contributing to this outcome include immune compromise of the host, antimicrobial resistance, wound-healing deficiencies, and the adherence of pathogens to themselves and wound surfaces via an impenetrable, resistant biofilm.".
These results firmly suggested that if you have a weakened immune system you have a substantially increased risk of chronic bacterial infection.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In finding a natural ingredient or whole food for the prevention and treatment of infection with little or no side effects researchers evaluated the effects of ginger against the monogenean parasite Gyrodactylus turnbulli.
The tested ethanolic and aqueous extracts were prepared for freeze-dried ginger.
An increase in extract concentration was associated with reduced time to parasite immobilization.
Injection at concentrations of 5 and 40ppt ethanolic extract induced parasite death at 26.1±0.7 and 4.9±0.3min, respectively. The ethanolic extract was more efficient. At 75 and 200ppt aqueous ginger extract, induced parasites died at 65.6±2.8 and 1.8±0.2min, respectively.
Bathing G. Turnbull-infected fish in the ethanolic ginger extract (i.e. 5 and 7.5ppt for 90 and 30min, respectively) significantly reduced infection prevalence and intensity.
The higher concentration (i.e. 7.5ppt) proved to be effective as those of Praziquantel, the conventional chemical.
Interestingly, oral treatments of G. Turnbull-infected guppies with diets supplemented with 10 and 20% ginger powder also proved to be ineffective in decreasing parasite load.
Furthermore, in schistosome mansonii-infected mice, extract given daily for 45 days beginning at either 2nd day or 45 days post-infection showed a reduction of worm burden and the egg load in the liver and intestine which coincided with the reduction in granuloma diameters.
Ginger extract exerted a potential effect in reducing some inflammatory mediators that play a crucial role in schistosomal liver fibrosis and its complications.
The in-depth analysis also suggested that ginger extract also minimizes the deleterious effects of inflammatory and oxidative stress markers in the tested mice.
Taken altogether, ginger extracts with the abundant bioactive compound may be used for the prevention and treatment of parasite-infected diseases, pending the larger and multi-center human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Efficacy of ginger-based treatments against infection with Gyrodactylus turnbulli in the guppy (Poecilia reticulata (Peters)) by Levy G1, Zilberg D2, Paladini G1, Fridman S. (PubMed)
(2) Efficiency of ginger (Zingbar officinale) against Schistosoma mansoni infectionduring host-parasite association by Aly HF1, Mantawy MM. (PubMed)
(3) Dietary Onion or Ginger Modulates the Stress Response and Susceptibility to Vibrio harveyi JML1 Infection in Brown-marbled Grouper Epinephelus fuscoguttatus Juveniles by Amar EC1, Apines-Amar MJS2, Faisan JP Jr1. (PubMed)
(4) Treatment of chronic infection by Cierny G 3rd1, DiPasquale D. (PubMed)
#Enzyme #Bromelain Inhibits the Symptoms of #FunctionalDyspepsia Cuased by Helicobacter Pylori Infection, According to Studies
By Kyle J. Norton
Functional dyspepsia, also known as indigestion, is a symptom in the stomach associated with difficulty in digesting food.
The most common symptoms of indigestion are pain or discomfort in your upper abdomen (dyspepsia) or burning pain behind the breastbone (heartburn) soon after eating.
Some patients may also experience symptoms of feeling full or bloated with no signs of relief.
In serious cases, patients may also experience symptoms of vomiting blood, dark, tarry stools due to damage to the lining of the stomach, shortness of breath, and unexplained weight loss.
If you have some of the aforementioned symptoms, please check with the doctor immediately
There exact causes of indigestion are multiple. Epidemiologically, female gender, aging, long-term use of pain relievers, such as aspirin and ibuprofen, smoking, and people with long-term psychological problems such as anxiety or depression are some most common factors found in patients with functional dyspepsia.
Conventionally, treatment of functional dyspepsia is totally depending on the condition, including antibiotics for H. pylori infection and medication to reduce pain.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding potential and natural compounds for the treatment of functional dyspepsia, researchers examined a dietary integrator composed of sodium alginate, sodium bicarbonate, bromelin, and essential oils in patients affected by functional dyspepsia.
The study included a study of a total of 100 patients with functional dyspepsia diagnosed primarily on the basis of typical symptoms and the exclusion of non-functional gastrointestinal diseases.
According to the symptom classification, All patients were assigned to either dysmotility-like dyspepsia (N.=60) or reflux-like dyspepsia (N.=40).
All patients were treated with TUBES Gastro (0.80 g oral tablets bid after main meals) for 4 weeks, on top of their current treatment with proton pump inhibitors or not.
According to the results from the experiment, TUBES Gastro showed a high statistically significant reduction of the Numerical Rating Scale (NRS) scores at 14 and 28 days: -1.5 (-26.3%) and -3.4 (-59.6%), respectively compared to the baseline in patients with dysmotility-like dyspepsia.
In patients with reflux-like dyspepsia, TUBES Gastro demonstrated a statistically significant reduction of the NRS score at 14 and 28 days: -2.8 (-41.2%) and -4.8 (70.6%), respectively (P<0.0001).
Furthermore, there were no side effects found during the study duration.
Based on the findings, researchers wrote, "TUBES Gastro treatment was effective and well-tolerated in reducing the symptomatology of patients affected by functional dysmotility-like and reflux-like dyspepsia".
In order to reveal additional information of TUBES Gastro anti-functional dyspepsia, researchers at the Molinette Hospital conducted a study to examine the preparation efficacy on a total of 53 consecutive patients (22 males, 31 females; mean age, 54+/-2.5 years) with functional dyspepsia and negative for Helicobacter pylori infection.
Patients classified to four subgroups according to predominant symptom: ulcer-like dyspepsia, Motility-like dyspepsia, reflux-like dyspepsia, and nonspecific dyspepsia, were received TUBES gastro (0.80 g oral tablets bid) for a minimum of 3 months (range, 3-11).
According to the results of patients who completed the study, the preparation showed a strong effect on the improvement in Visual Analogue Scale (VAS). score.
Compared to the based line, the difference in scores between the initial and the final visit was -1.9+/-2.1 cm (range, -6 to +3), or 23.8+/-40.8% (range, -150% to 100%).
Dr. Pellicano R, the lead scientist wrote, "The study results indicate that in the short term TUBES, gastro can significantly improve dyspeptic symptoms in dyspeptic patients negative for H. pylori infection".
Taken altogether, bromelain used alone or combined with other remedies may be considered supplements for the prevention and treatment of functional dyspepsia, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Can dietary integrators provide a clinical benefit in the treatment of functional dyspepsia? results from a prospective study with TUBES Gastro by Molteni M. (PubMed)
(2) Benefit of dietary integrators for treating functional dyspepsia: a prospective pilot study.[Article in English, Italian] by Pellicano R1, Strona S, Simondi D, Reggiani S, Pallavicino F, Sguazzini C, Bonagura AG, Rizzetto M, Astegiano M. (PubMed)
Functional dyspepsia, also known as indigestion, is a symptom in the stomach associated with difficulty in digesting food.
The most common symptoms of indigestion are pain or discomfort in your upper abdomen (dyspepsia) or burning pain behind the breastbone (heartburn) soon after eating.
Some patients may also experience symptoms of feeling full or bloated with no signs of relief.
In serious cases, patients may also experience symptoms of vomiting blood, dark, tarry stools due to damage to the lining of the stomach, shortness of breath, and unexplained weight loss.
If you have some of the aforementioned symptoms, please check with the doctor immediately
There exact causes of indigestion are multiple. Epidemiologically, female gender, aging, long-term use of pain relievers, such as aspirin and ibuprofen, smoking, and people with long-term psychological problems such as anxiety or depression are some most common factors found in patients with functional dyspepsia.
Conventionally, treatment of functional dyspepsia is totally depending on the condition, including antibiotics for H. pylori infection and medication to reduce pain.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding potential and natural compounds for the treatment of functional dyspepsia, researchers examined a dietary integrator composed of sodium alginate, sodium bicarbonate, bromelin, and essential oils in patients affected by functional dyspepsia.
The study included a study of a total of 100 patients with functional dyspepsia diagnosed primarily on the basis of typical symptoms and the exclusion of non-functional gastrointestinal diseases.
According to the symptom classification, All patients were assigned to either dysmotility-like dyspepsia (N.=60) or reflux-like dyspepsia (N.=40).
All patients were treated with TUBES Gastro (0.80 g oral tablets bid after main meals) for 4 weeks, on top of their current treatment with proton pump inhibitors or not.
According to the results from the experiment, TUBES Gastro showed a high statistically significant reduction of the Numerical Rating Scale (NRS) scores at 14 and 28 days: -1.5 (-26.3%) and -3.4 (-59.6%), respectively compared to the baseline in patients with dysmotility-like dyspepsia.
In patients with reflux-like dyspepsia, TUBES Gastro demonstrated a statistically significant reduction of the NRS score at 14 and 28 days: -2.8 (-41.2%) and -4.8 (70.6%), respectively (P<0.0001).
Furthermore, there were no side effects found during the study duration.
Based on the findings, researchers wrote, "TUBES Gastro treatment was effective and well-tolerated in reducing the symptomatology of patients affected by functional dysmotility-like and reflux-like dyspepsia".
In order to reveal additional information of TUBES Gastro anti-functional dyspepsia, researchers at the Molinette Hospital conducted a study to examine the preparation efficacy on a total of 53 consecutive patients (22 males, 31 females; mean age, 54+/-2.5 years) with functional dyspepsia and negative for Helicobacter pylori infection.
Patients classified to four subgroups according to predominant symptom: ulcer-like dyspepsia, Motility-like dyspepsia, reflux-like dyspepsia, and nonspecific dyspepsia, were received TUBES gastro (0.80 g oral tablets bid) for a minimum of 3 months (range, 3-11).
According to the results of patients who completed the study, the preparation showed a strong effect on the improvement in Visual Analogue Scale (VAS). score.
Compared to the based line, the difference in scores between the initial and the final visit was -1.9+/-2.1 cm (range, -6 to +3), or 23.8+/-40.8% (range, -150% to 100%).
Dr. Pellicano R, the lead scientist wrote, "The study results indicate that in the short term TUBES, gastro can significantly improve dyspeptic symptoms in dyspeptic patients negative for H. pylori infection".
Taken altogether, bromelain used alone or combined with other remedies may be considered supplements for the prevention and treatment of functional dyspepsia, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Can dietary integrators provide a clinical benefit in the treatment of functional dyspepsia? results from a prospective study with TUBES Gastro by Molteni M. (PubMed)
(2) Benefit of dietary integrators for treating functional dyspepsia: a prospective pilot study.[Article in English, Italian] by Pellicano R1, Strona S, Simondi D, Reggiani S, Pallavicino F, Sguazzini C, Bonagura AG, Rizzetto M, Astegiano M. (PubMed)
#Herbal #Chastetreeberry Reduces #Symptoms of #PremenstrualSyndrome #PMS, According to Studies
By Kyle J. Norton
Chaste tree berry, the queen of all herbs may have potency in reducing symptoms and treatment of premenstrual syndrome.
According to Dr. Döll M, the extract of chaste tree berry decreased levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress-involved expression of symptoms of PMS.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered a Queen herb in treating menstrual problems and discomforts and used in herbal medicine for thousands of years as an aphrodisiac agent.
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed significantly reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycles) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) orally administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to the placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women studies also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Taking together, Chaste tree berry may be a safe herbal medicine for the treatment of PMS, through decreased levels of prolactin, negative factors, and ameliorated symptoms of the syndrome in many aspects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1.(PubMed)
(2) Treatment for the premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
Chaste tree berry, the queen of all herbs may have potency in reducing symptoms and treatment of premenstrual syndrome.
According to Dr. Döll M, the extract of chaste tree berry decreased levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress-involved expression of symptoms of PMS.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered a Queen herb in treating menstrual problems and discomforts and used in herbal medicine for thousands of years as an aphrodisiac agent.
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed significantly reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycles) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) orally administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to the placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women studies also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Taking together, Chaste tree berry may be a safe herbal medicine for the treatment of PMS, through decreased levels of prolactin, negative factors, and ameliorated symptoms of the syndrome in many aspects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1.(PubMed)
(2) Treatment for the premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
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