#Antioxidant #Alliin Inhibits the Risk of #ChronicInflammation, Researchers Suggest

By Kyle J. Norton

Inflammation is a natural defense of the immune system that protects the body against the invasion of harmful stimuli and pathogens.

In the acute phase of infection, the immune first line of defense white blood cells, macrophages stimulates the production of proinflammatory cytokines with an aim to destroy all invaders which try to enter the body.

Most cases of acute infection are stopped at this phase and the wound is healed quickly.

However, if the wound is too large, then the recovery may take a longer period of time and through 4 overlap recovery stages.

Any interruption in the overlapped recovery stage may cause the formation of scars, similar to those of overproduction of pro-inflammatory cytokines.

Diseases associated with chronic inflammation induced by protein, lipid, and cellular damage include cardiovascular disease, diabetes, neurodegenerative disease,... and cancers.

In other words, prolonged low-grade inflammation caused by continuing the production of pro-inflammatory cytokines due to an immune response that can not kill off all invaders in a set period between 3-8 weeks can result in serious and chronic diseases.

The results have been found to cause cell death and alternation of cell DNA.

Believe it or not, people with low-grade chronic inflammation are prone to psychological stress that links to a greater risk for depression, and heart disease. particularly the body's ability to regulate the inflammatory response and normal defense.

Out of many risk factors involved in the onset of chronic inflammatory diseases, some researchers suggested the promotion of a high-fat diet in the Western world may correlate to the rise of the condition.

Dr. Yehui Duan, the lead scientist wrote, "In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has been increasingly viewed as a significant modifiable risk factor for diseases such as diabetes and certain types of cancer".

And, "the recent scientific literature about HFD-induced inflammation and subsequent development of diseases and cancer, with an emphasis on mechanisms involved. Given the expanding global epidemic of excessive HFD intake, understanding the impacts of an HFD on these medical conditions, gaining great insights into possible underlying mechanisms, and developing effective therapeutic strategies are of great importance".

Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.

In the urgency to find a natural and potential compound for the treatment of diseases associated with inflammation, researchers examined the active component is alliin (S-allyl cysteine sulfoxide) anti-inflammatory activity.


Before incubated with alliin, lipopolysaccharide- (LPS-) stimulated 3T3-L1 adipocytes showed a significant increase in proteins involved in the production of pro-inflammatory cytokines, including IL-6, MCP-1, and Egr-1 in 3T3-L1 adipocytes exposed to 100 ng/mL LPS for 1 hour.

According to the tested assay in lipopolysaccharide- (LPS-) stimulated 3T3-L1 adipocytes incubated for 24 h with 100 μmol/L alliin, the bioactive compound inhibited such increase.

Furthermore, the overexpression of the phosphorylation of ERK1/2 associated with cell differentiation including cell death caused by LPS-induced inflammation in adipocytes was also decreased following alliin treatment.

Additionally, alliin prevented the expression of inflammation in facilitating the alternation of cell DNA by modulating the gene expressions involved in immune responses such as tumor-suppressive genes and inhibiting the genes related to cancer.

Dr. Saray Quintero-Fabián, the lead scientist wrote, " The present results have shown that alliin is able to suppress the LPS inflammatory signals by generating an anti-inflammatory gene expression profile and by modifying adipocyte metabolic profile".


Taken altogether, alliin may be considered a supplement for the prevention and treatment of diseases associated with inflammation, depending on the confirmation of the larger sample size and multicenter human study.

Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes by Saray Quintero-Fabián,1,2 Daniel Ortuño-Sahagún,1 Manuel Vázquez-Carrera,3 and Rocío Ivette López-Roa. (Hindawi)
(2) Inflammatory Links Between High Fat Diets and Diseases by Yehui Duan,1,† Liming Zeng,2,† Changbing Zheng,3 Bo Song,3 Fengna Li,1 Xiangfeng Kong,1and Kang Xu. (PMC)

#Herbal #Catsclaw Inhibits the Risk of #AutoimmuneDiseases, Scientists Say

By Kyle J. Norton

In breast cancer patients, Uncaria tomentosa exhibited its bioactive immunomodulators' effects in regulating the immune system against irregular cell growth and inflammation.

Immunomodulatory compounds exerted the above properties found in the cat's claw include ajoene, arctigenin, β-carotene, curcumin, epigallocatechin-3-gallate, ginseng, glabridin, and quinic acid, according to Dr. Baraya YS, the lead researcher.

'
A herbal immunomodulators review, in vitro and in vivo, also suggested cat's claw expressed the regulation of informational molecules such as cytokines through the alternation of immune function. Therefore, the medical plant may be a potential therapeutic modality for the treatment of many different conditions involving cytokine, including inflammation and autoimmune diseases.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine for over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc...

Autoimmune diseases are the disorder caused by the immune system attacking the body's healthy cells.
Cat's claw (Uncaria tomentosa) may be the next medical plant used for the treatment of autoimmune diseases through its stimulated immune effects.

Severe dengue is a disease associated with changes in the endothelial barrier function due to the production of inflammatory mediators by immune cells, U. tomentosa exerted antiviral and immunomodulatory activities in the inhibition of antigen and proinflammatory cytokine.

In fact, the significant effect of immunomodulation may introduce Cat's claw, as a promising candidate for clinical application.

The use of this herbal plant should be taken with care as toxicity has been found in some cases of overdoses.

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Sources
(1) Uncaria tomentosa increases growth and immune activity in Oreochromis niloticus challenged with Streptococcus agalactiae by Yunis-Aguinaga J1, Claudiano GS2, Marcusso PF2, Manrique WG2, de Moraes JR3, de Moraes FR4, Fernandes JB1. (PubMed)
(2) The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review by Baraya YS1, Wong KK2, Yaacob NS3.(PubMed)
(3) Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators by Spelman K1, Burns J, Nichols D, Winters N, Ottersberg S, Tenborg M.(PubMed)
(4) Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2 by Reis SR1, Valente LM, Sampaio AL, Siani AC, Gandini M, Azeredo EL, D'Avila LA, Mazzei JL, Henriques Md, Kubelka CF. (PubMed)
(5) Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis by Valerio LG Jr1, Gonzales GF. (PubMed)

#Bilberry Inhibits the Risk of #Alzheimer's disease (AD) with No Side Effects, Researchers Find

By Kyle J. Norton

Alzheimer's disease (AD) is a neurodegenerative disease found mostly in the aging population characterized by impaired memory, thinking, and behavior. caused by the gradual loss or death of neurons. These symptoms are slowly getting worse over time and becoming severe enough to interfere with daily activity.
60 percent to 80 percent of dementia found in the US is involved in Alzheimer's disease (AD).

According to the statistics, the number of patients living with AD is growing fast, affecting over 5.5 million people aged 65 and older. AD is the sixth leading cause of death in the US. Most patients AD lives four to eight years after diagnosis. However, the years of survival rate is totally depending on other factors.

In contrast to general belief, getting old is a risk factor for AD but AD is not a disease of aging. Approximately 200,000 Americans under the age of 65 have younger-onset Alzheimer’s disease.

As of today, there is no cure for AD, the aim of treatment is to slow down the severity of the symptoms and delay the progression of the disease.

In other words, treatment is to improve the quality of life for both patients and their caregivers.

Besides aging, being physically active, smoking, excessive alcohol drinking, medical conditions such as metabolic syndrome, and stress are some of the prevalent risks of AD.

Some researchers in the investigation of the correlation between obesity and AD wrote, "There is ample scientific as well as empirical evidence that obesity and its metabolic and vascular comorbidities are related to AD and likely in the causative pathway".

And, "Obesity prevention and treatment could prove to be an efficacious and safe approach to preventing AD, a serious and daunting epidemic disease".

Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.

In searching a natural ingredient for the treatment of Alzheimer's disease with no side effects, researchers at the effects of different polyphenols on neuroprotection and APP processing under different stress conditions in transgenic AD mice (APdE9).

Selected mice induced free radical toxicity and apoptosis in human SH-SY5Y neuroblastoma cells overexpressing APP751.

APdE9 mice fed with anthocyanin-rich bilberry showed decreased Amyloid Precursor Protein (APP)APP C-terminal fragment levels, an indication of reduced death of neurons in the cerebral cortex compared to APdE9 mice fed with the control diet.

Furthermore, soluble Aβ40 and Aβ42 levels, the plaque in the brain associated with increased risk for AD, mild cognitive impairment, and cognitive decline were significantly decreased in bilberry-fed mice, compared to blackcurrant-fed mice.

Moreover, the bilberry diet protected the spatial working memory of aged APdE9 mice, compared to mice on the control diet, thus reducing the risk of deficits.

The results clearly suggested bilberry diet protects the integrity and viability of the neuron in the brain against the risk of AD.

Dr. Vepsäläinen S, the lead scientist said, "These data suggest that anthocyanin-rich bilberry and blackcurrant diets favorably modulate APP processing and alleviate behavioral abnormalities in a mouse model of AD".

In order to reveal more information about bilberry anti AD activity, researchers examined the anthocyanoside extracts (Vaccinium myrtillus anthocyanoside (VMA)) obtained from bilberry on the aggregation and deposition of the amyloid beta (Aβ1-42) peptide in fibrillar form.

According to the tested assays, injection of VMA-protected Neuro2a cells by inhibiting the formation of Aβ peptide fibrils and reducing the toxicity of these aggregates in vitro.

A diet containing 1% VMA was found to exhibit significant activity in the prevention of cognitive degeneration in AD-tested mice.


Interestingly, VMA promoted the cognitive ability accompanied not by a reduction in an aggregate deposition in brains, but rather an increase in insoluble deposits compared to control diet mice.

In other words, bilberry protected the brain neuro against the risk of AD by diverting Aβ aggregation to insoluble deposits, an alternate, non-toxic form.

Taken altogether, bilberry processed abundantly bioactive compound anthocyanoside may be considered a functioning remedy for the prevention and treatment of AD, pending the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anthocyanin suppresses the toxicity of Aβ deposits through diversion of molecular forms in vitro and in vivo models of Alzheimer's disease by Yamakawa MY, Uchino K, Watanabe Y, Adachi T, Nakanishi M, Ichino H, Hongo K, Mizobata T, Kobayashi S, Nakashima K, Kawata, (PubMed)
(2) Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease by Vepsäläinen S1, Koivisto H, Pekkarinen E, Mäkinen P, Dobson G, McDougall GJ, Stewart D, Haapasalo A, Karjalainen RO, Tanila H, Hiltunen M. (PubMed)
(3) Obesity as a risk factor for Alzheimer's disease: weighing the evidence by Alford S1, Patel D2,3, Perakakis N4, Mantzoros CS. (PubMed)

#Healthyfood #Avocado Inhibits the Onset of #ProstateCancer in Vitro, Scientists Find

By Kyle J. Norton

Avocados are a commercially valuable fruit cultivated in tropical climates throughout the world. The fruit has a green-skinned, pear-shaped fruit that ripens after harvesting, native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.

The fruit contains campesterol, high amounts of β-sitosterol; fatty acids (approximately 60% monounsaturated, 20% saturated, and 20% unsaturated); high amounts of glutathione (27.7 mg/100 g); approximately 2% protein; 6–9% carbohydrates and sugars (glucose, fructose, d-mannoheptulose, a taloheptulose, and an alloheptulose); two bitter substances (1-acetoxy-2,4-dihydroxyheptadeca-16-ene and 1,2,4-trihydroxyheptadeca-16-ene); carnitine; proanthocyanidins; persenones A and B(a).


Intake of dietary MUFA from whole fruit of avocado are associated to reduced risk and treatment of prostate cancer, the new study at the University of the West Indies suggested(1). 

In support of the above, the University of California study showed that the anti prostate cancer effect is not a result of a single ingredient such as related carotenoids (zeaxanthin, alpha-carotene, and beta-carotene), lutein but the interaction of all ingredients in the whole fruit in combination with other det-derived phytochemicals through cell cycle arrest and G(2)/M cell cycle arrest accompanied by an increase in p27 protein which involves function as tumor suppressor in controlling the cell cycle progression, in incubated PC-3 cells(3). 

The Purdue University study in the evaluation of the anti cancers effect of avocado also showed a positive effect of the whole fruit in inhibition of six human tumor cell lines in culture, including human prostate adenocarcinoma (PC-3) cells(4).

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References
(a) Leung's Encyclopedia of Natural Ingredients:Chemical Composition of Avocado
(1) Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica by Jackson MD1, Walker SP, Simpson-Smith CM, Lindsay CM, Smith G, McFarlane-Anderson N, Bennett FI, Coard KC, Aiken WD, Tulloch T, Paul TJ, Wan RL.(PubMed)
(2) Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances. by Lu QY1, Arteaga JR, Zhang Q, Huerta S, Go VL, Heber D.(PubMed)
(3) Cytotoxic and insecticidal constituents of the unripe fruit of Persea americana by Oberlies NH1, Rogers LL, Martin JM, McLaughlin JL.(PubMed)

#Healthyfood #Leeks Gobble Up Breast Cancer Cells in Vitro, Scientists Say

By Kyle J. Norton

Cancer is a class of diseases in which a group of cells grows and multiplies disorderly and uncontrollably in our body.

Breast cancer is a medical and chronic condition caused by cell growth irregularly and uncontrollably in the breast tissue. At the early stage, in most cases, breast cancer starts in the cells of the inner lining tissue of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

At the advanced stage, breast cancer cells caused by the alternation of DNA can travel far away from the primary site to infect other healthy tissue and organs.

Most patients at early may have a lump when touching with no symptoms.

Patients who inherited the genetic preposition of BRCA1 and 2 are associated with over 60% of the risk of breast cancer.

The findings for effective treatments are ongoing with some successes, but the discovery of effective ingredients prevention and treatment of breast cancer with little or no side effects have proven difficult.

Detection of tumorigenesis through self-observation is still the best approach to discovering breast cancer in an early stage.

According to statistics, in 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the US alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.

Genetic preposition, one of the prevalent risk factors associated with the increased risk of breast cancer has been under intensifying study by scientists around the world over a few decades ago, suggested that women who carry the mutated genes BRCA1 and 2 have 60% most likely risk to develop breast cancer before the age of 70.

Another prevalent and most mentioned risk factor associated with the risk of the disease is obesity.

According to statistics, the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.

Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed and usually reach maturity in the autumn months, and have few pest or disease problems.


On finding a potential plant that processes anti-cancer activity researchers examined the effects of leek extracts on MCF-7 human breast cancer cells.

According to the crude extracts of ethanol, methanol, and water of leek obtained by maceration that were applied to MCF-7 cells in complete media at 37 °C and subjected to different treatments that involved varying concentrations (10, 50, and 100 μg/mL) of leek extracts for 24, 48, and 72 h of incubation, leeks showed a strong effect on cell viability and the concentration of extracts on MCF-7 cells.

The water leak extract proved to be the most effective extract at 50 μg/mL,

The efficacy of leek was attributed to the significant inhibition ability of the main chemical anandamide A-β-D-glucopyranoside found in the vegetable.

However, the mechanism of phytochemicals associated with the causes of breast cancer cell death was not identified in the study.

Taken altogether, leeks may be considered a functional food for the prevention and treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.


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How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparative Study of Onion (Allium cepa) and Leek (Allium ampeloprasum): Identification of Organosulphur Compounds by UPLC-QTOF/MS and Anticancer Effect on MCF-7 Cells by Zamri N1, Hamid HA. (PubMed)

#Tomatoes Inhibit the Onset of #HeartDisease by Modulating the Expression of Hormone Angiotensin, Researchers Show

By Kyle J. Norton

Under normal conditions, angiotensin is a type of hormone, belongings to the renin-angiotensin system (RAS), that regulates the constriction of blood vessels and blood pressure.

The hormone also plays a critical role in the retention of sodium by the kidney through its stimulation of the production of aldosterone from the adrenal cortex activated by the nerves (neurological)that is responsible for the desire for salt.

However, overexpression of angiotensin may induce fluid and sodium retention, blood vessels to constrict and increase blood pressure.

Most cases of overproduction of angiotensin have been found in patients with heart failure and an enlarged heart.

On the other hand, underexpression of angiotensin may lead to retention of potassium, reduced levels of sodium and fluid and lower blood pressure.

According to the University of Ferrara, Ferrara, overproduction of angiotensin II the other members of the renin-angiotensin system (RAS), seems to be one of the most aggressive, often causing several principal diseases such as arteriosclerosis, hypertension, coronary artery disease, and heart failure.

Furthermore, angiotensin II also is found to induce vascular damage mediated by the activation of transcription factors, redox signaling systems, and production of endogenous growth factors that lead to an induced immune response in the production of inflammatory cytokines.

Based on the results, researchers found that by reviewing the complexity of the RAS in pathological processes, RAS blockers may provide some mechanistic responses to the beneficial effects in the treatment of cardiovascular diseases.


Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find the natural ingredient for the treatment of blood vessel constriction, researchers examined the anti-angiotensin converting enzyme (ACE) factors in aqueous extract of tomato.


The study included sugar-free tomato extract (TE) which was tested for its anti-ACE activity using human plasma and rabbit lung pure ACE.

In 100 g tomatoes produced 72.2 ± 4.7 mg of TE used in the experiment, researchers found the extract inhibited plasma ACE activity in a dose-dependent manner.

The TE maximum effect in the inhibition of ACE enzyme was found to be at an IC50 value of 1.40 ± 0.04 mg/ml.
Furthermore, the commercially available sugar-free TE, Fruitflow(®)-2 showed similar amounts of catechin also exerted a similar inhibitory potency against plasma ACE activity.

In order to find more information about tomato anti-ACE activity, researchers examined the effect of lycopene on angiotensin II-induced oxidative stress in H9c2 cells.


In this study, tested H9c2 cells were divided into 6 groups: control group, Ang II group (1 µmol/L), Ang II (1 µmol/L) + low dose Lyc (3.125 nmol/L) group, Ang II (1 µmol/L) + moderate dose Lyc (6.25 nmol/L) group and Ang II (1 µmol/L) + high dose Lyc (12.5 nmol/L) group and Lyc group (12.5 nnmol/L).

Groups treated with lycopene showed significant improvement of cell survival and reduction of ROS generation in a dose-dependent manner compared to control.

Co-treatment of lycopene also reversed the levels of MDA significantly increased in Ang II-treated cells, in a dose-dependent manner.


Furthermore, the levels of a protein associated with oxidative stress caused by the cascade of free radicals found in Ang II-treated cells also inhibited the injection of lycopene.

Based on the finding, researchers said, "Lyc could attenuate Ang II-induced oxidative stress and this effect is linked with its capacity of reducing ROS generation and enhancing cellular ROS scavenging ability in H9c2 cells".

Taken altogether, tomatoes may be considered supplements for the prevention and treatment of angiotensin caused by oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.


Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition of angiotensin-converting enzyme by aqueous extract of tomato by Biswas D1, Uddin MM, Dizdarevic LL, Jørgensen A, Duttaroy AK. (PubMed)
(2) [Lycopene attenuates angiotensin II induced oxidative stress in H9c2 cells]. [Article in Chinese] by Liu Y1, Tang Q2, Hu Z1, Deng W1, Li L. (PubMed)
(3) Angiotensin II overproduction: enemy of the vessel wall by R. Ferrari1, G. Guardigli1, G. Cicchitelli1, M. Valgimigli1, E Merli1, O. Soukhomorskaia1, and C. Ceconi. (University of Ferrara, Ferrara)
(4) Role of the Renin-Angiotensin System in Vascular Diseases by M. Ruiz-Ortega, O. Lorenzo, M.Rupérez, V. Esteban, Y. Suzuki, S. Mezzano, J.J. Plaza, and J. Egido. (Hypertension)

How #Herbal #Ashwagandha Effects the Body Mass, and Strength in Resistance Training Exercise

By Kyle J. Norton

Body mass calculated by the body mass index (BMI), is a value derived from the mass (weight) and height of a person.
The BMI index = weight (kg)/ height (m2)

Weight loss is a process that intentionally reduces the total body mass, through the decrease of fluid, body fat or adipose tissue or lean mass.

Obesity is a medical condition of excess body fat that has accumulated over time, while overweight is a condition of excess body weight relative to height.

According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered overweight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of the American population is either overweight or obese.

In North America, over 68% of the US population is either overweight or obese.

Weight loss products is a 66 billion business in the US, according to the statistic provided by the Marketdata LLC research firm. And the business continues to grow at a rapid rate.

Resistance training is a type of exercise associated with the improvement of muscular strength and endurance used most in professional athletics.

The exercise is emphasized to move the limbs against resistance provided by your body weight, gravity, bands, weighted bars, or dumbbells.

Today, most resistance training exercise is performed against exercise machines.

Body strength on the resistance training exercise is a type of workout that focuses on the entire body to build lean muscle tissue and strength.

Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for enhancing the results of resistance training, researchers examined the effects of ashwagandha root extract consumption on muscle mass and strength in healthy young men engaged in resistance training.

The randomized, prospective, double-blind, placebo-controlled clinical study included 57 young male subjects (18-50 years old) with little experience in resistance randomized into treatment (29 subjects) consumed 300 mg of ashwagandha root extract twice daily and placebo (28 subjects) groups consumed starch for 8 weeks.

Compared to the placebo subjects, the group treated with ashwagandha had significantly greater increases in muscle strength on the bench-press exercise and the leg-extension exercise and significantly greater muscle size increase in the arms.

Furthermore, the Ashwagandha treatment group also showed a significant increase in muscle size in the chest.

Furthermore, the Ashwagandha treatment group also reduced the risk of exercise-induced muscle damage by stabilizing the serum creatine kinase and increasing the production of testosterone levels. compared to the control.

Most importantly, compared to the control, the Ashwagandha treatment group demonstrated a significantly greater decrease in body fat percentage.

Based on the findings, researchers said, "Ashwagandha supplementation is associated with significant increases in muscle mass and strength and suggests that ashwagandha supplementation may be useful in conjunction with a resistance training program".

Taken altogether, Ashwagandha may be considered a functional herb that increases body mass and strength in resistance training, pending the result of a larger sample size and multicenter study


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial by Wankhede S1, Langade D2, Joshi K3, Sinha SR4, Bhattacharyya S. (PubMed)