By Kyle J. Norton
Gut Microbiota is a community of microorganisms living in our gut. Under normal conditions, the ratio of the gut microbiome composition is balanced.
However, the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle may alternate the ratio by increasing the growth of "bad" bacterias, leading to the development of chronic diseases such as inflammatory bowel disease, obesity, cancer, and autism.
In other words, imbalanced of the gut microbiota may have a strong and negative impact on the immunity, the digestive, fat, and carbohydrate metabolism, and the central nervous system
* In immunity, the balance of the gut microbes showed to stimulate the immune function against inflammatory immune disorders.
* In the digestive system, balanced gut microbes protect the gut against gastrointestinal diseases and non-gastrointestinal diseases. caused by overexpression of bad bacteria.
* In carbohydrate metabolism, gut microbes influence the nutrient extraction from the diet, thus reducing the risk of obesity and obesity complications.
* Neurologically, gut microbiota can control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.
Out of many prevalent factors that cause the onset of the unbalanced ratio of gut microbiota, some researchers suggested that the Western diet may have negatively influenced to induce overgrowth of bad microorganisms in the gut.
Dr. Marit K. Zinöcker, the lead scientist wrote, "Western diet promotes inflammation that arises from both structural and behavioral changes in the resident microbiome"
And, "The environment created in the gut by ultra-processed foods, a hallmark of the Western diet, is an evolutionarily unique selection ground for microbes that can promote diverse forms of inflammatory disease".
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound that enhances the gut microbiome's composition, researchers compared the effects of carrot, cucumber, and broccoli seed flours extracts with 50% acetone on gut microbiota modulating capacity.
In vitro, all three seed flour extracts enhanced the total number of gut bacteria and altered the abundance of specific bacterial phylum or genus.
In other words, cucumber showed a potential effect to improve the ratio of gut microbiota in the flavor of the "good" bacterias, similar to those of carrot and broccoli.
In J774A.1 cells, cucumber also exerted a similar activity by protecting the microbiota that exhibits anti-inflammatory activity by suppressing LPS induced production of pro-inflammatory cytokines, such as IL-1β and COX-2 mRNA expressions.
Furthermore, in obesity, induced progression of metabolic disorders, especially type 2 diabetes (T2DM), cucumber not only improved IR in obese mice and relieving inflammation in adipose tissue and blood but also enhanced the microbiota composition ratios.
More precisely, cucumber improved the ratio of gut microbiome composition by promoting IR and reducing inflammation.
Taken altogether, cucumber may be used for the improvement of gut microbiota, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chemical Compositions of Cold-Pressed Broccoli, Carrot, and Cucumber Seed Flours and Their in Vitro Gut Microbiota Modulatory, Anti-inflammatory, and Free Radical Scavenging Properties by Choe U1, Li Y1,2, Gao B2, Yu L1, Wang TTY, Sun J, Chen P, Liu J3, Yu L. (PubMed)
(2) Therapeutic Effect of Cucumis melo L. Extract on Insulin Resistance and the gut microbiome in Lepob/Lepob Mice by Lee D1, Yoo JH1, Lee BC. (PubMed)
(3) The Western Diet–Microbiome-Host Interaction and Its Role in Metabolic Disease by Marit K. Zinöcker1, and Inge A. Lindseth. (PMC)
Thursday, 11 March 2021
Tuesday, 9 March 2021
Cranberry Processes Immune-Modulatory Activity
By Kyle J. Norton
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
In other words, the immunomodulatory activity is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.
Sources
(1) Gut-targeted immunonutrition boosting natural killer cell activity using Saccharomyces boulardii lysates in immuno-compromised healthy elderly subjects by Naito Y1, Marotta F, Kantah MK, Zerbinati N, Kushugulova A, Zhumadilov Z, Illuzzi N, Sapienza C, Takadanohara H, Kobayashi R, Catanzaro R. (PubMed)
(2) Active and passive immunity, vaccine types, excipients and licensing by David Baxter(Oxford Academic)
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
Active immunity may also be artificially acquired caused by the injection of the vaccine, a substance that contains antigen and passive immunity is an auto-response of the immune system against infection through the production of antigen.
Immunity can also be passive and active, Dr. David Baxter, in the article of "Active and passive immunity, vaccine types, excipients and licensing" wrote, "Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long-lasting—even lifelong" and " Passive immunity refers to the process of providing IgG antibodies to protect against infection; it gives immediate, but short-lived protection—several weeks to 3 or 4 months at most. Passive immunity is usually classified as natural or acquired".
However, an abnormal immune response such as overactive and underactive may cause a weakened immune system or autoimmune diseases.
However, an abnormal immune response such as overactive and underactive may cause a weakened immune system or autoimmune diseases.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, the immunomodulatory activity is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
The human trial included healthy volunteers with years of age ranging from 65-79 years with low natural killer (NK) cell activity,
According to the differentiation, liquid C-1317 showed a strong improvement in NK cell activity.
In other words, the select remedy resulted in immune-modulatory effects on the treatment group, compared to placebo at the end of 2 months.
Based on the findings, researchers said, " Although preliminary, these beneficial immune-modulatory effects of KC-1317 in aged individuals might indicate its employment within a wider age-management strategy".
On finding a potential compound for the treatment of diseases associated with immune compromise, researchers investigated the immunomodulatory effect of KC-1317 (a symbiotic mixture containing Saccharomyces boulardii lysate in a cranberry, colostrum-derived lactoferrin, fragaria,
In other words, the select remedy resulted in immune-modulatory effects on the treatment group, compared to placebo at the end of 2 months.
Based on the findings, researchers said, " Although preliminary, these beneficial immune-modulatory effects of KC-1317 in aged individuals might indicate its employment within a wider age-management strategy".
Taken altogether, cranberry combined with other herbal medicine may be considered immune-modulatory remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Gut-targeted immunonutrition boosting natural killer cell activity using Saccharomyces boulardii lysates in immuno-compromised healthy elderly subjects by Naito Y1, Marotta F, Kantah MK, Zerbinati N, Kushugulova A, Zhumadilov Z, Illuzzi N, Sapienza C, Takadanohara H, Kobayashi R, Catanzaro R. (PubMed)
(2) Active and passive immunity, vaccine types, excipients and licensing by David Baxter(Oxford Academic)
Monday, 8 March 2021
Fresh Cabbages, the Natural Antioxidants
By Kyle J. Norton
The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.
by
In some cases, this reaction also is caused by a long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
Moreover, fresh cabbage consumption induced a higher antioxidant capacity in volunteer plasma than that of fermented cabbage intake.
The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.
by
In some cases, this reaction also is caused by a long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
There is no single cause of oxidative stress. The onset of oxidative stress may include cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.
Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
According to the results of the randomized crossover study of 13 volunteers who consumed fresh and fermented red cabbage, red cabbage products contained antioxidants of 20 different nonacylated and acylated anthocyanins with the main structure of cyanidin triglucosides.
Furthermore, the bioavailability of anthocyanin from fresh red cabbage was over 10% higher than from fermented red cabbage.
Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.
In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.
Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention of oxidative stress in the progression of cardiac diseases, researchers examined the effect of red cabbage fermentation on anthocyanin bioavailability and plasma antioxidant capacity in humans.
In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.
Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention of oxidative stress in the progression of cardiac diseases, researchers examined the effect of red cabbage fermentation on anthocyanin bioavailability and plasma antioxidant capacity in humans.
In other words, fresh cabbage processes a higher antioxidant capacity compared to fermentation.
Collectively, researchers said, "The study has shown that fermentation process affects red cabbage anthocyanins bioavailability and human plasma antioxidant capacity".
Taken altogether, cabbage processed abundantly phytochemicals may be considered a remedy for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The impact of red cabbage fermentation on bioavailability of anthocyanins and antioxidant capacity of human plasma by Wiczkowski W1, Szawara-Nowak D2, Romaszko J. (PubMed).
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The impact of red cabbage fermentation on bioavailability of anthocyanins and antioxidant capacity of human plasma by Wiczkowski W1, Szawara-Nowak D2, Romaszko J. (PubMed).
Sunday, 7 March 2021
NHE-06 (Dandelion + 5 Other Herbal Medicines) Formula Kills Liver Cancer Cells in Intact Immunity Animals
By Kyle J. Norton
The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm, and above your stomach.
The liver not only plays a critical role to filter the blood coming from the intestine before passing them to other parts of the body but also protects our body against toxins by detoxifying chemicals and metabolizes drugs.
Furthermore, the liver produces bile that not only aids the digestive function in food absorption but also builds strong cell membranes, produces vitamin D and steroid hormone.
Additionally, the liver also inhibits oxidative stress by producing the antioxidant enzyme that counters the expression of free radicals in the body.
Liver cancer is a medical condition characterized by cell growth irregularly in the liver tissue.
The causes of liver cancer are associated with the alternation of cells DNA which normally begins in the cells on the surface of the inner lining.
Liver cancer at the early stage no not cause any symptoms. However, at the advanced stage, liver cancer cells can cause a wide range of symptoms including jaundice, abdominal swelling and pain, and dark urine and white stool accompanied by the general symptoms of cancers such as unintended weight loss, loss of appetite, chronic fatigue and tiredness and gastrointestinal discomforts.
The most common cause of liver cancer is infected by the hepatitis virus. However, in North America, due to the overexpression of the overweight and obese population, liver cancer may be slowly progressed from nonalcoholic fatty liver disease through cirrhosis to liver cancer.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of cancer, scientists examined a novel herbal formula NHE-06, a water-decocting extract from six natural herbals, Ficus carica, Taraxacum mongolicum, Angelica Sinensis, Lonicera japonica, Pseudo-ginseng, and Folium ginkgo. anti-liver cancer activity.
However, NHE-06 was only effective in intact immunity mice, compared to no effect in immunocompetent mice.
Based on the findings, researchers said, " the novel formula of the anti-inflammatory NHE-06 effectively restores antitumor immunosurveillance and can be applied for prevention and/or treatment of inflammation-related cancers".
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma by Lu X1, Wo G2, Li B1, Xu C2, Wu J3, Jiang C4, Wei J. (PubMed)
The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm, and above your stomach.
The liver not only plays a critical role to filter the blood coming from the intestine before passing them to other parts of the body but also protects our body against toxins by detoxifying chemicals and metabolizes drugs.
Furthermore, the liver produces bile that not only aids the digestive function in food absorption but also builds strong cell membranes, produces vitamin D and steroid hormone.
Additionally, the liver also inhibits oxidative stress by producing the antioxidant enzyme that counters the expression of free radicals in the body.
Liver cancer is a medical condition characterized by cell growth irregularly in the liver tissue.
The causes of liver cancer are associated with the alternation of cells DNA which normally begins in the cells on the surface of the inner lining.
Liver cancer at the early stage no not cause any symptoms. However, at the advanced stage, liver cancer cells can cause a wide range of symptoms including jaundice, abdominal swelling and pain, and dark urine and white stool accompanied by the general symptoms of cancers such as unintended weight loss, loss of appetite, chronic fatigue and tiredness and gastrointestinal discomforts.
The most common cause of liver cancer is infected by the hepatitis virus. However, in North America, due to the overexpression of the overweight and obese population, liver cancer may be slowly progressed from nonalcoholic fatty liver disease through cirrhosis to liver cancer.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of cancer, scientists examined a novel herbal formula NHE-06, a water-decocting extract from six natural herbals, Ficus carica, Taraxacum mongolicum, Angelica Sinensis, Lonicera japonica, Pseudo-ginseng, and Folium ginkgo. anti-liver cancer activity.
According to the tested analysis, in Vitro and Vivo, NHE-06 showed a significant suppression against NF-κB/IL-6/STAT3 signaling associated with activation of pro-inflammation in related cancer and enhancement of antitumor immunity in both cancer cell line and HCC-bearing mice.
In Vivo, the application of NHE-06 demonstrated strong activity in both preventive and therapeutic functions.
Based on the findings, researchers said, " the novel formula of the anti-inflammatory NHE-06 effectively restores antitumor immunosurveillance and can be applied for prevention and/or treatment of inflammation-related cancers".
Taken altogether, dandelion may be considered a remedy for the protection against liver cancer in intact immunity patients, pending the confirmation of the larger sample size and multicenter human study.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma by Lu X1, Wo G2, Li B1, Xu C2, Wu J3, Jiang C4, Wei J. (PubMed)
Friday, 5 March 2021
Collard Green Promotes Bile Acid Binding Activity
By Kyle J. Norton
Bile acids synthesized by oxidation from cholesterol in the liver, that flow to the gallbladder to aid digestion.
Bile acid-binding is a process to interferes with normal fat digestion and absorption including the prevention of absorption of fat-soluble vitamins such as A, D, E, and K.
In other words, the binding of bile acids (BAs) may have a strong effect to lower blood cholesterol levels by increasing the excretion of bile acids in the stool and reducing the amount of bile acid returning to the liver.
By inhibiting the levels of bile acid caused by a certain type of liver/bile duct disease such as partial biliary obstruction, levels of cholesterol can be controlled.
Conventionally, the effects of bile acid sequestrant are limited. Low doses of 8 gram/day of Cholestyramine, a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption can lower LDL cholesterol by 10%-15% compared to high doses of 24 gram/day of only 25%.
In other words, bile acid-binding medicine such as Cholestyramine used alone is less effective, compared to statins in lowering LDL cholesterol.
The most common symptoms associated with the intake of Cholestyramine are constipation, diarrhea, stomach/abdominal pain, bloating, nausea, vomiting, and loss of appetite.
Bile acid sequestrants such as lovastatin combined with niacin may be used to lower aggressively lower LDL cholesterol levels.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
On finding a potential plant that process bile acid-binding activity researchers compared the effects of
various vegetables, using a mixture of bile acids secreted in human bile under physiological conditions.
Based on the tested results, the significantly different (P < or = .05) health-promoting potential are collard greens = kale = mustard greens > broccoli > Brussels sprouts = spinach = green bell pepper > cabbage as indicated by their bile acid binding on dry matter basis.
Bile acids synthesized by oxidation from cholesterol in the liver, that flow to the gallbladder to aid digestion.
Bile acid-binding is a process to interferes with normal fat digestion and absorption including the prevention of absorption of fat-soluble vitamins such as A, D, E, and K.
In other words, the binding of bile acids (BAs) may have a strong effect to lower blood cholesterol levels by increasing the excretion of bile acids in the stool and reducing the amount of bile acid returning to the liver.
By inhibiting the levels of bile acid caused by a certain type of liver/bile duct disease such as partial biliary obstruction, levels of cholesterol can be controlled.
Conventionally, the effects of bile acid sequestrant are limited. Low doses of 8 gram/day of Cholestyramine, a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption can lower LDL cholesterol by 10%-15% compared to high doses of 24 gram/day of only 25%.
In other words, bile acid-binding medicine such as Cholestyramine used alone is less effective, compared to statins in lowering LDL cholesterol.
The most common symptoms associated with the intake of Cholestyramine are constipation, diarrhea, stomach/abdominal pain, bloating, nausea, vomiting, and loss of appetite.
Bile acid sequestrants such as lovastatin combined with niacin may be used to lower aggressively lower LDL cholesterol levels.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
On finding a potential plant that process bile acid-binding activity researchers compared the effects of
various vegetables, using a mixture of bile acids secreted in human bile under physiological conditions.
The study compared the mixture of 8 replicate incubations which were conducted for each treatment simulating gastric and intestinal digestion, including a substrate only, a bile acid mixture only, and 6 with the substrate and bile acid mixture with Cholestyramine (a cholesterol-lowering, bile acid-binding drug) as the positive control treatment and cellulose as the negative control on bile acid-binding activity
In other words, collard green scored the highest bile acid-binding activity, similar to those of kale and mustard greens.
More important, steam cooking significantly was found to enhance the bile acid-binding property of the collard green, compared to those of uncooked.
Collectively, researchers said, "These green/leafy vegetables, when consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer, advance human nutrition research, and improve public health".
More important, steam cooking significantly was found to enhance the bile acid-binding property of the collard green, compared to those of uncooked.
Collectively, researchers said, "These green/leafy vegetables, when consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer, advance human nutrition research, and improve public health".
Taken altogether, collard green, particularly the stream veggie may be considered a functional food to enhance the bile acid-binding activity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kahlon TS1, Chiu MC, Chapman MH. (PubMed)
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kahlon TS1, Chiu MC, Chapman MH. (PubMed)
Thursday, 4 March 2021
Omega -3 Fatty Acids Inhibit the Onset of Nonalcoholic Fatty Liver Disease
By Kyle J. Norton
According to the results of the experiment, humans with NAFLD and NASH; and preclinical mouse models of NASH, showed a high abundance of hepatic saturated (SFA) and monounsaturated (MUFA) fat, but a low abundance of hepatic C20-22 ω3 PUFA.
In other words, the imbalance of such change has been found to induce hepatic lipotoxicity, inflammation, oxidative stress, and fibrosis.
Furthermore, recent meta-analyses and clinical trials in the evaluation of the capacity of C20-22 ω3 PUFA suggested that dietary supplementation improves health outcomes in adults and children with preexisting NAFLD.
Additionally, diets supplemented with docosahexaenoic acid (DHA, 22 : 6,ω3) alone or with eicosapentaenoic acid (EPA, 20 : 5,ω3) are tolerated and effective at lowering liver fat in NAFLD patients.
Based on the evidence, researchers said, "dietary supplementation with C20-22 ω3 PUFA should be considered as a viable and effective option to lower liver fat in obese adults and children with NAFLD".
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.
Non-alcoholic fatty liver disease is a condition of fatty liver diseases as a result of the accumulated of fat in the liver, not caused by abusive alcohol consumption.
Nonalcoholic fatty liver disease (NAFLD) is emerging as a widespread condition in the US, approximately 30% of the adult population are obese.
Nonalcoholic fatty liver disease (NAFLD) is emerging as a widespread condition in the US, approximately 30% of the adult population are obese.
The disease is also manifested by steatosis, steatohepatitis, cirrhosis.
Obesity is associated linearly to the prevalent risk of nonalcoholic fatty liver disease (NAFLD).
In conventional medicine, treatments of NAFLD mainly focus on weight loss accompanied to pharmacologic therapy in control of insulin resistance and dyslipidemia.
As of today, there is no effective pharmacologic therapy approved specifically and directly for the treatment of nonalcoholic fatty liver disease (NAFLD).
Obesity is associated linearly to the prevalent risk of nonalcoholic fatty liver disease (NAFLD).
In conventional medicine, treatments of NAFLD mainly focus on weight loss accompanied to pharmacologic therapy in control of insulin resistance and dyslipidemia.
As of today, there is no effective pharmacologic therapy approved specifically and directly for the treatment of nonalcoholic fatty liver disease (NAFLD).
The exact causes of NAFLD aren't well understood. Some researchers suggested that certain risk factors such as long-term use of certain medications(8), genetic preposition(8), insulin resistance(8), high cholesterol(8) and triglycerides(8) in the blood, polycystic ovary syndrome(8), metabolic syndrome(8), obesity(8), and type 2 diabetes(8) are associated with the onset of the disease.
Recent studies also found that people with obstructive sleep apnea(11), underactive thyroid (hypothyroidism(10), and underactive pituitary gland (hypopituitarism) (9) also at an increased risk of the NALFD.
Some researchers suggested that an unhealthy diet such as a high-fat diet may also have a strong implication on NAFLD(12)(13).
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of chronic liver diseases, researchers examined the efficacy of C20-22 ω3 polyunsaturated fatty acids (PUFA) on NAFLD in adults and children.
Some researchers suggested that an unhealthy diet such as a high-fat diet may also have a strong implication on NAFLD(12)(13).
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
On finding a potential phytochemical for the treatment of chronic liver diseases, researchers examined the efficacy of C20-22 ω3 polyunsaturated fatty acids (PUFA) on NAFLD in adults and children.
Additionally, diets supplemented with docosahexaenoic acid (DHA, 22 : 6,ω3) alone or with eicosapentaenoic acid (EPA, 20 : 5,ω3) are tolerated and effective at lowering liver fat in NAFLD patients.
Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of non-alcoholic fatty liver, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children: where do we stand? by Spooner MH1, Jump DB. (PubMed)
(2) Non-alcoholic Fatty Liver Disease (NAFLD)Treatment in Phytochemicals Perspective by Kyle J. Norton
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children: where do we stand? by Spooner MH1, Jump DB. (PubMed)
(2) Non-alcoholic Fatty Liver Disease (NAFLD)Treatment in Phytochemicals Perspective by Kyle J. Norton
Wednesday, 3 March 2021
Tocopherols, the Potential Supplementations for the Prevention of Osteoradionecrosis
By Kyle J. Norton
Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.
Osteoradionecrosis is a condition associated with bone death due to radiation or radiation treatment.
Furthermore, the combination of drug therapy was well tolerated and showed a promising result for the treatment of mandibular osteoradionecrosis.
Moreover, in an18 consecutive patients previously irradiated for head and neck cancer-induced mandible, ORN with the length of the exposed bone (L) was 13.4 +/- 8 mm, and the mean of 12.6 +/- 4.9, either given a daily oral combination of 800 mg of PTX and 1000 IU of vitamin E for 6 to 24 months between June 1995 and January 2002 with eight patients who were the worst cases were given 1600 mg/day clodronate 5 days a week, all patients improved at 6 months, with 84% mean L and 67% mean SOMA score reductions.
Additionally, 18 patients achieved complete recovery, 14 in 5 +/- 2.6 months, compared to only two patients who exhibited a 75% response at 6 months.
Collectively, researchers said, "PTX-vitamin E boosted by clodronate is an effective treatment of mandibular ORN that induces mucosal and bone healing in a median period of 6 months".
Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.
Osteoradionecrosis is a condition associated with bone death due to radiation or radiation treatment.
The death of bone cells is a result of radiation induce-damage of the blood vessel that supplies the nutrients to the bone.
Osteoradionecrosis is a rare side effect occurred sometime after radiation therapy has ended. The complication usually occurs in the lower jaw or mandible.
According to the research of the related study of subjects, the combination of pentoxifylline plus tocopherol with or without clodronate was effective for the treatment of mandibular osteoradionecrosis.
Most of the identified studies were found to be from retrospective case series.
The numbers of studies were generally scarce.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of side effects induced by radiotherapy, researchers evaluated the healing benefit provided by the antioxidant and antifibrotic properties of pentoxifylline-tocopherol or pentoxifylline-tocopherol-clodronate in combination therapy for osteoradionecrosis.
On finding a potential phytochemical for the treatment of side effects induced by radiotherapy, researchers evaluated the healing benefit provided by the antioxidant and antifibrotic properties of pentoxifylline-tocopherol or pentoxifylline-tocopherol-clodronate in combination therapy for osteoradionecrosis.
The numbers of studies were generally scarce.
Moreover, in an18 consecutive patients previously irradiated for head and neck cancer-induced mandible, ORN with the length of the exposed bone (L) was 13.4 +/- 8 mm, and the mean of 12.6 +/- 4.9, either given a daily oral combination of 800 mg of PTX and 1000 IU of vitamin E for 6 to 24 months between June 1995 and January 2002 with eight patients who were the worst cases were given 1600 mg/day clodronate 5 days a week, all patients improved at 6 months, with 84% mean L and 67% mean SOMA score reductions.
Additionally, 18 patients achieved complete recovery, 14 in 5 +/- 2.6 months, compared to only two patients who exhibited a 75% response at 6 months.
Collectively, researchers said, "PTX-vitamin E boosted by clodronate is an effective treatment of mandibular ORN that induces mucosal and bone healing in a median period of 6 months".
Taken altogether, tocopherols used in a combination with other medicines including pentoxifylline may be considered a supplement for reducing the side effects of radiotherapy, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pentoxifylline, tocopherol, and clodronate for the treatment of mandibular osteoradionecrosis: a systematic review by Martos-Fernández M1, Saez-Barba M2, López-López J3, Estrugo-Devesa A3, Balibrea-Del-Castillo JM4, Bescós-Atín C. (PubMed)
(2) Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial by Delanian S1, Depondt J, Lefaix JL. (PubMed)
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pentoxifylline, tocopherol, and clodronate for the treatment of mandibular osteoradionecrosis: a systematic review by Martos-Fernández M1, Saez-Barba M2, López-López J3, Estrugo-Devesa A3, Balibrea-Del-Castillo JM4, Bescós-Atín C. (PubMed)
(2) Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial by Delanian S1, Depondt J, Lefaix JL. (PubMed)
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