Cranberry, A Gastric Protective Remedy

By Kyle J. Norton

The stomach formed part of the digestive system that receives food from the esophagus before passing them to the small intestine is a muscular organ located on the left side of the upper abdomen.

The stomach is the first line of food digestive by secreting acid and enzymes.

Gastric protection is the process or action that protects the stomach by increasing the production of gastric (stomach) mucus with an aim to protect the stomach wall.

The most common diseases associated with the stomach are
*Gastric/Stomach cancer is a medical and chronic condition caused by the cell growth irregularly and disorderly in the cells on the surface of the inner lining tissue before penetrating deeper into other layers of the stomach to form a tumor, due to the alternation of DNA.

* Gastritis

Gastritis is a group of conditions associated with the inflammation of the lining of the stomach caused by infection of the bacterium, leading stomach ulcers developing.

* A stomach ulcer is an open sore in the lining of the stomach. In most cases, it is a result of bacterial infection that leads to the erosion of the gastric lining by stomach acid.

* Atrophic gastritis is a condition of loss of gastric glandular cells caused by long-term inflammation of the stomach mucous membrane (mucosa).

Loss of the gastric glandular cells in the long term eventually is replaced by intestinal and fibrous tissues.

* Gastric ulcers

Gastric ulcer, a type of peptic ulcer is defined as a condition of localized tissue erosion in the lining of the stomach.

Most cases of stomach diseases are associated with infection, such as with Helicobacter pylori. and the most common symptoms of stomach diseases are nausea, bloating, diarrhea and abdominal pain.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the protection of the stomach, researchers investigated the effects of drinking cranberry juice on H. pylori infection.

According to the review of selected studies, cranberry juice showed significant activity in preventing H. pylori adhesion in vitro to the human gastric mucosa.

In Vivo, cranberry juice fed to mice infected with H. pylori, 80% were cured 24 h following treatment, with an eradication rate of 20%, 4 wk post-treatment.

Moreover, cranberries in the combination with traditional anti-H. pylori antibiotics such as metronidazole and clarithromycin were proven proved effective in improving eradication rates and suppressing infections in endemic populations.

Additionally, the inhibitory action of cranberries against H. pylori was attributed to its effect on the inhibition of adhesion, biofilm formation blocking.

Taken altogether, cranberry combined with conventional medicines may be considered a gastric protective remedy for the management of obesity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Non-pharmacological treatment of Helicobacter pylori by Haim Shmuely, Noam Domniz, and Jacob Yahav. (PMC)

Common Fig or Fig (Ficus carica) Processes Anti Stomach/Gastric Cancer Activity in Vitro

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

The stomach plays a critical role to assist the digestive system in digesting foods by secreting acid and enzymes.

Stomach cancer is a condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach caused by the alternation of the cell DNA. Adenocarcinoma is the most common type of stomach cancer.

According to the statistics, most cases of gastric/stomach cancer are found in older people. The average age of people when they are diagnosed is 68. The risk of developing gastric/stomach cancer in a man lifetime is about 1 in 95.

According to the American Cancer Society, in 2018, approximately 26,240 new cases of stomach cancer were diagnosed, including 6,520 men and 9,720 women, and gastric cancer caused the death of 10,800 people including 6,510 men and 4,290 women.

The 5 years survival rate of localized gastric cancer is 67%, compared to the advanced stage of only 31%.

Most patients with stomach cancer in the early stage are asymptomatic.

However, at the later stage, patients may experience symptoms of pain and/or discomfort in the stomach area, mild ache in the upper part of the body, difficulty swallowing, feeling full or bloated after a small mealy, and vomiting blood or having blood in the stool accompanied by general symptoms shared by other types of cancer, including unintentional weight loss, loss of energy, tiredness, nausea, and vomiting and loss of appetite.

Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of malignant tumors researchers examined the effect of fig tree latex (Ficus carica) on stomach cancer line.

The study included different doses of fig tree latex that were incubated with the stomach cancer cell line and the peripheral blood mononuclear cells in a period of 72 hours.
According to the tested differentiation,
* Fig tree latex showed a significant anti-cancer activity by blocking the proliferation of cancer cell lines through its cytotoxicity without causing harm to human normal cells.

* Furthermore, the stomach cancer cell line was more sensitive to Ficus carica latex than normal cells.

Moreover, Ficus carica latex induced cancer cell death might be attributed to the presence of proteolytic enzymes, which has been found to be involved in the degradation of the cancer cells extracellular matrix and inhibited cancer invasion and metastasis.

Taken altogether, common fig or fig (Ficus carica)  may be considered a remedy for the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line by Hashemi SA1, Abediankenari S, Ghasemi M, Azadbakht M, Yousefzadeh Y, Dehpour AA. (PubMed)

Tocopherols Inhibits the Initiation, Progression and Treatment of Lung Cancer

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancers is derived from epithelial cells.

In the US, lung cancer is the leading cause of cancer deaths, including 88,329 men and 70,354 women, according to the 2007 statistic.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

Researchers do not the exact causes of lung cancer. 

Genetic mutation inherited from the parents is a result of an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to increase a person's chance of developing lung cancer.

However, not all people who carry mutated lung cancer genes will develop lung cancer.

On the cigarette smoking in risk of lung cancer, researchers believe cigarette containing high amount of cancer-causing substances (carcinogens), when inhaled, the cigarette smoke carried the chemical toxins to the lung cell directly, and prolonged periods exposed to such chemicals can alternate lung cell DNA, leading to the early onset of lung cancer.

Some researchers suggested genetic mutation and long-term cigarette smoking are 2 major risk factors associated with the alternative of lung cell DNA.

Truly, according to the statistic, approximately 8% of lung cancers are inherited or occur as a result of a genetic predisposition.

On finding a potential phytochemical for the treatment of lung diseases, researchers examined the growth inhibitory effect of a gamma-tocopherol-enriched tocopherol mixture (gammaTmT) against CL13 murine lung cancer cells grown in culture and as subcutaneous tumors in A/J mice.

According to the analysis,
* GammaTmT had no effect after 2 days and weakly inhibited the growth of CL13 in culture after 5 days (28% growth inhibition at 80 microM).

* Furthermore, dietary treatment at doses of 0.1 and 0.3% gammaTmT for 50 days inhibited the growth of CL13 tumors in A/J mice by 53.9 and 80.5%, respectively.

* According to the histopathological analysis, gammaTmT revealed an increase in tumor necrosis compared to control tumors.

* Moreover, dietary treatment with gammaTmT dose-dependently increased gamma- (10.0-37.6-fold) and delta-tocopherol (8.9-26.7-fold) in the tumors of treated mice compared to controls.

* Additionally, dietary treatment with gammaTmT also increased plasma gamma- (5.4-6.7-fold) and delta-tocopherol (5.5-7-fold). Whereas others have demonstrated the cancer-preventive activity of gammaTmT against mammary and colon cancer, this is the first report of growth inhibitory activity against lung cancer.

Taken altogether, tocopherols may be considered a supplement for reducing the risk of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition by Zarogoulidis P1, Cheva A, Zarampouka K, Huang H, Li C, Huang Y, Katsikogiannis N, Zarogoulidis K. (PubMed)
(2) Inhibition of lung cancer growth in mice by dietary mixed tocopherols by Lambert JD1, Lu G, Lee MJ, Hu J, Ju J, Yang CS. (PubMed)

Herbal Ashwagandha Protects the Heart Tissues Against Cardio-Toxicity

By Kyle J. Norton

Cardiotoxicity is a condition caused by toxin accumulated in the heart that leads to damage to the heart muscle.

Cardiotoxicity reduced the heart pumping blood capability, leading to a decrease in oxygen-rich blood to nourish the body tissues and organs.

The most common symptoms of cardiotoxicity, are tiredness fatigue, chronic cough, water retention and shortness of breath.

If you have experienced some of the aforementioned symptoms that can be healed within a week or 2, please check with your doctor to rule out the possibility.

The most common causes of cardiotoxicity are associated with patients receiving chemotherapy and the intake of certain medications. However, infection, excessive alcohol consumption, medical conditions such as diabetes and thyroid disease, high blood pressure and thiamine and Vitamin B deficiency have also been found to induce cardiotoxicity.

Cardiomyopathy is a severe case of cardiotoxicity.

Cardiomyopathy in most occurs in patients under chemotherapy. However, a group of diseases or disorders can also lead to the damaged heart muscle. Injury to the heart muscle may induce cardiomyopathy, including viruses - such as human immunodeficiency virus (HIV), infection, long-standing high blood pressure, chronic or long-term alcohol use, and diabetes.

Conventionally, treatment of cardiotoxicity depending on the cause of the disease may include
* Beta-blockers, for the improvement of the blood flow and reduction of palpitations, arrhythmias, and high blood pressure.

*ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow.

* Diuretics, by getting rid of excess fluids that reduce heart function in blood pumping

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

In the urgency to discover a natural ingredient for the prevention of cardiovascular diseases, researchers examined the protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.

According to the results of the experiment, doxorubicin (10 mg/kg) -induced cardiac toxicity in male Wistar rats showed an increase of necrosis and apoptosis in heart tissues.

Furthermore, the elevation of malondialdehyde and protein carbonyl levels and catalase activity associated with the expression of oxidative stress also wee found in the doxorubicin (10 mg/kg) rats.

The doxorubicin (10 mg/kg) rats also exhibited depletion of total antioxidant capacity and of superoxide dismutase level in cardiac tissues, accompanied by the increases of myeloperoxidase activity, total calcium content, and the expression of Bcl-2 protein in heart tissues.

Most importantly, all parameters induced by the injection of doxorubicin alterations were effectively attenuated by the administration of the purified standardized extract (1.5% withanolides; manufactured by Idea Sphere Inc., American Fork, UT, USA) of Withania somnifera (300 mg/kg).

Based on the evidence, researchers said, "Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug".

Taken altogether, Ashwagandha may be considered supplements for the prevention and treatment of Cardiotoxicity induced by medications,  pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats by Hamza A1, Amin A, Daoud S. (PubMed)

Cruciferous Vegetables Kill Non-Small Cell Lung Cells in Vitro

By Kyle J. Norton

Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

The lung is a vital organ of the humans located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells. In the US.

Most common types of lung cancers include
* Squamous-cell carcinoma often found in an outer area of the lung,

* Large-cell carcinoma found in the center of the lung by an air tube

* Adenocarcinoma found in any part of the lung.

Non-small cell lung cancer, the most common type of lung cancer, usually grows and spreads methodically and predictably.

The most common risk factors of non-small cell lung cancer (NSCLC) are long term smoking and people exposed to long-term second-hand smoke.

According to the statistics, 2019, approximately 228,150 adults including 116,440 men and 111,710 women in the United States will be diagnosed with non-small cell lung cancer (NSCLC). Lung cancer makes up about 13% of all new cancer diagnoses. Black men are about 20% more likely to get lung cancer than white men.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the treatment of lung cancer, researchers examined the anti-metastatic activity of Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables on two non-small cell lung cancer (NSCLC) cell lines, A549, and CL1-5 cells.

SFN exhibited more potent cytotoxicity against suspending rather than adherent cancer cells.

The inhibition of SFN was attributed to the induction of anoikis. evidenced by a loss of normal cell-matrix interactions, markers of apoptosis, and activation of the mitochondrial apoptotic pathway.

Furthermore, SFN also inhibited NSCLC cell to form spherical colonies, to induce proliferation.

Moreover, SFN also suppressed the activation of signaling pathways to induce cancer cell adhesion.

Based on the findings, researchers said, "These results provide new insight into mechanisms underlying the chemopreventive ability of SFN and suggest a potential benefit of SFN to interfere with tumor metastasis".
 

Taken altogether, Cruciferous vegetables may be considered functional foods for the prevention and treatment of non-small cell lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The chemopreventive isothiocyanate sulforaphane reduces anoikis resistance and anchorage-independent growth in non-small cell human lung cancer cells by Tsai JY1, Tsai SH1, Wu CC. (PubMed)

Omega -3 Fatty Acids May Be Effective Against Psoriasis, Some Studies Show

By Kyle J. Norton

Psoriasis is a skin condition characterized by the speeds up of the life cycle of skin cells, leading to cells build up rapidly on the surface of the skin.

Symptoms of psoriasis caused by the extra skin cells form scales and red patches can be itchy and painful.

Epidemiologically, psoriasis patches can range from a few spots or large areas. A most common form of psoriasis is plaque psoriasis, a condition that induces dry, raised, red skin lesions (plaques) covered with silvery scales.

The causes of psoriasis are not identified, however, researchers believed that genetic proposition exacerbated by certain factors such as weather, injury, illness, or stress are some of the most causative factors that induce the onset of the condition.

Certain risk factors such as family history, viral and bacterial infections, weakened immune systems, persistent stress, are associated with the risk of psoriasis.

Other risk factors associated with psoriasis may include skin injury that did not heal properly, people who are obese and side effects of long term use of certain medicines such as oral steroids.

Some researchers suggested smoking that has a strong impact on the immune system may also be one of the major causes of psoriasis in smokers.

Conventionally, topical corticosteroids are the most commonly prescribed medication for the treatment fo the condition, particularly in patients with mild to moderate psoriasis.

According to the joint study led by the University of Trieste, the increased incidence of a large number of diseases that share an inflammatory origin probably due to the pro-inflammatory cytokine spillover from active psoriatic lesions, leading to a large inflammation on distant tissues(95).

Additionally, the Brigham and Women's Hospital, and Harvard Medical School, Boston joint study suggested, individuals with psoriasis have increased blood levels of uric acid. In the documented 2217 incident cases of gout during follow-up. Psoriasis was associated with an increased risk of subsequent gout with a multivariate HR of 1.71

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of skin diseases, researchers examined the efficacy and mechanism of action of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on psoriasis.

The Cochrane Central Register of Controlled Trials that search the databases of the PubMed/MEDLINE and EMBASE all randomized controlled trials and prospective observational studies compared the 3 PUFAs effects versus control in adult patients with psoriasis.

Out of 12 articles identified in a total of 732 articles that were searched, some studies found that n-3 PUFAs were associated with improvements in the PASI score, erythema, scaling, itching, an area involved and infiltration.

However, some studies did not find a reduction in scaling, erythema, area involved or thickness in the treatment group.

Based on the findings researchers said, "It is still inconclusive whether the use of n-3 PUFAs in patients with psoriasis is associated with improvements in the severity of psoriasis and other outcomes".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of psoriasis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of omega-3 fatty acids on disease severity in patients with psoriasis: A systematic review by Upala S1,2, Yong WC1, Theparee T3, Sanguankeo A. (PubMed)
(2) Efficacy of ω-3 supplementation in patients with psoriasis: a meta-analysis of randomized controlled trials by Clark CCT1, Taghizadeh M2, Nahavandi M2, Jafarnejad S. (PubMed)
(3) Increased airway inflammation in patients with psoriasis by Damiani G1, Radaeli A2, Olivini A2, Calvara-Pinton P3, Malerba M2. (PubMed)

(4) Psoriasis, psoriatic arthritis and risk of gout in US men and women by Merola JF1, Wu S2, Han J3, Choi HK4, Qureshi AA5.(PubMed)

Omega -3 Fatty Acids Lowers the Risk of Oral Cancer in Vivo

By Kyle J. Norton


Oral cancer is a medical condition characterized by irregular cell growth in the oral cavity, due to the alternation of cell DNA.

In the early stage, the abnormal cells only appear in the surface lining of the cavity. However, in the late stage, the infectious cells may travel a distance away from the original site to invade other cells and tissue.

Early diagnosed oral cancer may have a close to 100% recovery.

According to the cancer society, the 5 survival rate of oral cancer is about 60% plus without taking into consideration the stage of cancer.

According to the Oral Cancer Foundation in the article "Oral Cancer Fact", in the US, approximately, 50000 Americans will be diagnosed with oral pharyngeal cancer this year. It will cause about 10,000 deaths.

Family history, smoking, alcohol drinking, infected by HPV virus, poor hygiene and genetic preposition are some of the risk factors associated with the disease.

Most common types of oral cancer are
* Squamous cell carcinoma
Squamous cell carcinoma is one of the most common types of oral cancer accounting for over 90% of all cases and arises from the squamous cell layer in the lining of the oral cavity and oropharynx.

* Verrucous carcinoma
The low grade and rarely spread verrucous carcinoma is accounted for only approximately 5% of all cases. Cancer can spread deeply into the surrounding tissue.

* Minor salivary gland cancers
The cancer is originated from the salivary gland accounted for less than 1% of all cases.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases, researchers investigated the chemopreventive effects of various dietary n-6 and n-3 fatty acids in a 9,10-dimethyl-1,2-benz[a]-anthracene (DMBA)- and betel quid extract (BQE) -induced hamster oral cancer model.

The selected thirty 6-week-old adult male hamsters included in the study were divided into normal, low, and high dietary n-6 and n-3 fatty acid groups under DMBA + BQE treatment for 16 weeks.

According to the tested analysis,
* The low dietary n-6/n-3 fatty acid group exhibited a significantly lower tumor number, volume, and burden than those of the other groups.

In other words, high levels of n-3 fatty acids compared to low levels of n-6 fatty acids induced a strong inhibition of the initiation and progression of oral cancer cells.

In the right buccal pouch tissue, the low dietary n-6/n-3 fatty acid group had significantly lower nuclear factor-κB associated with pro-inflammatory expression, proliferating cell nuclear antigen, and cyclin D1 expression in cell cycle division.

More precisely, high levels of n-3 fatty acids compared to low levels of n-6 fatty acids inhibited the parameters involved in oral cancer proliferation.

Collectively, researchers concluded, " the lower dietary n-6/n-3 fatty acid ratio exerted chemopreventive effects in the DMBA- and BQE-induced hamster oral cancer model".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of oral cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Low dietary n-6/n-3 polyunsaturated fatty acid ratio prevents induced oral carcinoma in a hamster pouch model by Lee HC1, Liang A1, Lin YH2, Guo YR1, Huang SY. (PubMed)