Eyebright ( Euphrasia) Processes Anti-Oxidative Stress Activity

By Kyle J. Norton

Oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Long-term oxidative stress presented in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.

More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.

The Liver Pathophysiology, 2017 in the explanation of the cause of oxidative stress, wrote, " (1) the presence of xenobiotics, (2) the activation of the immune system in response to invading microorganisms (inflammation), and (3) radiation, which makes oxidative stress a common denominator of toxicity or stress".

In other words, oxidative stress may be preventable by following a diet rich in antioxidants such as a diet with higher fruits and vegetable consumption accompanied by moderate exercise and reducing intake of saturated and trans fat and processed foods.

On finding a natural ingredient for the prevention and treatment of chronic diseases, scientists examined the potential protective effects of a commercial eye drop (Dacriovis™) containing Matricaria chamomilla and Euphrasia officinalis extracts on human corneal epithelial cells (HCEC-12).

Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe. 

The plant has been used in traditional and herbal medicine to treat eye infection and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.

According to the tested analysis of human corneal epithelial cells (HCEC-12) exposed to UVB radiation followed by the treatment of the eye drops at a various concentration to induce oxidative stress,* The eye drops were able to protect corneal epithelial cells from UVB-induced cell death and ameliorated the wound healing; the eye drops exhibited a strong antioxidant activity.

* The eye drops exerted a strong antioxidant activity by decreasing ROS levels and protein and lipid oxidative damage.

* The eye drops also exerted anti-inflammatory activities by decreasing COX-2, IL-1β, iNOS expression that promote inflammation and counteracted UVB-induced GSS and SOD-2 expression induce oxidative stress and restored HO-1 expression to control levels.

Based on the results, researchers suggest, "...an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts exerts positive effects against UVB induced oxidative stress and inflammation and may be useful in protecting corneal epithelial cells from UVB exposure".

Taken altogether, Eyebright (Euphrasia) may be considered a remedy for the treatment of diseases involved oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Pharmacological activities of an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts in UVB-induced oxidative stress and inflammation of human corneal cells by Bigagli E1, Cinci L1, D'Ambrosio M1, Luceri C2. (PubMed)

Lycopene Inhibits Pulmonary Emphysema in Vivo

By Kyle J. Norton

The lung formed part of the circulatory system plays an essential and unique role in taking oxygen to the blood and exhaling carbon dioxide from the blood.

In other words, any diseases involved in breathing problems that reduce the function of the lung are pulmonary diseases.

Lung diseases are a group of medical conditions that cause the reduced function of the lung inhaling oxygen to the blood and exhaling carbon dioxide from the blood.

Pulmonary diseases are a class of diseases associated with the lungs, including asthma, COPD, influenza, pneumonia and tuberculosis, and lung cancer.

In other words, any diseases involved in breathing problems that reduce the function of the lung are pulmonary diseases.

Most common pulmonary diseases are asthma, a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood; pneumothorax, a condition of collection of air within the pleural cavity, from either the outside or from the lung, and bronchitis is a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma.

 Emphysema is a type of COPD with a long term and progressive condition that cause shortness of breath, depending to the stage of lung function associated with the damage of tissues of the air sacs (alveoli) in the lungs.

Most common causes of pulmonary emphysema, smoking, exposure to air pollution, such as chemical fumes, dust, and other substances and irritating fumes and dust at work.

Dr. Stephen I. Rennard, the lead scientist wrote, "Emphysema is characterized by enlargement of alveolar spaces together with destruction of alveolar walls in the absence of obvious fibrosis (1). Far and away, the most common cause of pulmonary emphysema is cigarette smoking".

And, "Cigarette smoke causes an inflammatory response in the lower respiratory tract characterized by the accumulation of pigment-laden alveolar macrophages together with the recruitment of smaller numbers of neutrophils (1, 2)".

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a potential compound for the treatment of colitis researchers examined the effects of lycopene on antioxidant and anti-inflammatory properties on emphysema.

Mice selected to the study were treated by two different doses of lycopene (25 or 50 mg/kg/day, diluted in sunflower oil by orogastric gavage before exposing to 60 days of CS or not (CG).

According to the tested analysis, lycopene not only promoted a reduction in the number of total leukocytes counts and improved patients with pulmonary emphysema.

Furthermore, lycopene promotes the balanced ratio of free radical and antioxidant enzymes by decreasing lipid peroxidation and DNA damage and increasing the activities of SOD, CAT and GSH content.

Levels of TNF-α, IFN-γ, and IL-10. which were elevated by the injection of CS were also decreased by the application of lycopene.

Additionally, the decrease of myeloperoxidase activity and nitrite content. associated with overexpression of free radicals induced inflammation was also inhibited by the lycopene.

Based on the findings, researchers said, " our data elucidated the role of lycopene as an antioxidant and anti-inflammatory agent in mice exposed to CS".

Taken altogether, lycopene found in tomato may be considered a remedy for the prevention and treatment of pulmonary emphysema, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lycopene mitigates pulmonary emphysema induced by cigarette smoke in a murine model by Campos KKD1, de Oliveira Ramos C1, Martins TL1, Costa GP2, Talvani A2, Garcia CCM3, Oliveira LAM4, Cangussú SD1, Costa DC5, Bezerra FS. (PubMed)
(2) Cigarette Smoke Inhibits Alveolar Repair. A Mechanism for the Development of Emphysema by Stephen I. Rennard , Shinsaku Togo , and Olaf Holz. (ATS Journals)

Devil's club (Oplopanax horridus) influences on Gut Microbiota and Colorectal Cancer Cells

By Kyle J. Norton

Gut microbiota is a community of microbes living in the gastrointestinal tract, including at least 1000 different species of known bacteria with more than 3 million genes.

Gut microbiota or gastrointestinal microbiota, the complex community of microorganisms play a critical role in a variety of metabolic functions, including produced vitamins, synthesized all essential and nonessential amino acids, and carried out biotransformation of bile.

Gut microbiota protects the intestinal structures and functions by attaching to the gut wall against the entry of pathogenic, enteroinvasive bacteria into the epithelial cells.

In a healthy individual, the levels of gut microbiota are balanced that allow the body to function in an optimal way.

Furthermore, gut microbiota also is found to stimulate the production of some vitamins (B and K), digest certain foods that the stomach and small intestine have not been able to digest, particularly in the combat against the aggression of other bad microorganisms.


However, alterations in gut microbiota composition have been found in patients with a low-grade inflammatory state, leading to an increased risk of several diseases, including type 2 diabetes mellitus and cardiovascular disease.

Overexpression of certain harmful bacterias in the gut such as E. coli can utilize a complex arsenal of virulence factors to colonize and persist in the intestine.

In other words, although the digestive tract can adapt to change, the loss of balance in gut microbiota may induce dysbiosis., leading to health problems of functional bowel disorders, inflammatory bowel disease, allergies, obesity, and diabetes.

The are many risk factors associated with gut microbiota imbalance. Some researchers suggested that the major causes of the condition may be a result of the promotion of a high-fat diet over the past few decades.

In the immune perspective, gut microbiota protects the intestines by alerting the immune response against foreign invasion through specific receptors, leading to an immune system in inducing the proinflammatory cytokines.

Devil's Club is a large shrub, genus Oplopanax, belonging to the family Aralioideae, native to the cool moist forests of western North America. 

The herb has been used in traditional and herbal medicine as Adaptogen, Antipyretic, Pain Reliever, Antitussive, Antibacterial agent and to treat Arthritis, Diabetes, Colds, Cough, Sore throat, Chest congestion, Stomach pain, Constipation, Gall stones, Influenza, Cancer, etc.

On finding a potential compound for improvement of digestive functioning, scientists examined the polyyne-enriched fraction (PEFO) from Devil's club effects on gut microbiota and colorectal cancer cells after oral administration.

According to the tested analysis,

* The antiproliferative effects of PEFO incubated with human gut microbiota for 72 h (PEFO I) was much lower than that of PEFO on HCT-116, SW-480, and HT-29 cells.

* PEFO possessed better anti-CRC activity in vivo, and significantly induced apoptosis of the CRC cells, which was associated with activation of caspase-3 in the induction of apoptosis.

More precisely, the anti-colorectal cancer activity of polyynes might be antagonized by some bio-converted metabolites after incubation with human gut microbiota.

Collectively, researchers said, "Therefore, it might be better for CRC prevention if the polyynes could be orally administrated as purified compounds".

Taken altogether, coltsfoot may be considered a remedy for the protection of gut functioning in patients with colorectal cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota by Wang J1,2, Shao L3, Rao T1,2, Zhang W1,2, Huang WH. (PubMed)

Herbal Elecampane (Inula helenium) Induces Acute Lymphoblastic Leukemia Cell Apoptosis

By Kyle J. Norton

Leukemia is a condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow is the soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.

According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes death 68,000 Americans.

Acute leukemia is a condition caused by a rapid increase in the numbers of extreme immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including 

*Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer of the abnormal growth of extremely immature lymphocytes overproduced by the bone marrow and/or lymphatic system.

Since All has a tendency to multiply quickly, it can lead to death to other normal white blood cells in the bone marrow and/or lymphatic system. In ALL, lymphocytes appear immature in the bloodstream.
Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

*Acute myelogenous leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of myelogenous lining cause of the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

On finding a natural ingredient for the prevention and treatment of leukemia, scientists examined the antitumor effect of Alantolactone (ALT), an active component of natural product Inula heleniumin on B cell acute lymphoblastic leukemia (B-ALL).

Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia. 

The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.

According to the tested analysis of B-ALL cells that were treated with various concentrations of ALT,

* ALT showed a good antitumor effect in B-ALL by inducing cytotoxicity.
* In vivo and in vitro, ALT induced the overexpression of ROS to cause cancer apoptosis by damaging the cancer cell DNA damage.

* In addition, the induction of over a load of ROS by ALT was attributed to the effects in the direct inhibition of reductase.

Based on the results, researchers suggest, "We found that ALT, a natural product, showing a promising tactic in the therapy of B-ALL by targeting ROS pathway".

Taken altogether, Dandelion may be considered a remedy for the treatment of acute lymphoblastic leukemia, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Targeting non-oncogene ROS pathway by alantolactone in B cell acute lymphoblastic leukemia cells by Xu X1, Huang L2, Zhang Z1, Tong J1, Mi J1, Wu Y3, Zhang C4, Yan H. (PubMed)

Elder (Sambucus), A Natural Antioxidant Herbal Remedy

By Kyle J. Norton

Total antioxidant capacity (TAC) is the test to evaluate the antioxidant response against the free radicals produced in a given disease induced by oxidative stress.

Oxidative stress is a medical condition caused by the unbalanced ratio of the levels of free radical and antioxidant enzymes produced by the host.

In fact, free radicals exist everywhere including the airs we breathe, the thing we eat and the environment we contact, particularly, cell metabolism in the body.

Epidemiologically, overexpression of free radicals has been found to induce damage to the cell, lipid, proteins, and alternation of cell DNA, leading to chronic diseases, such as cardiovascular diseases, diabetes and particularly, cancer.

Other diseases such as hypertension, dyslipidemia, peripheral artery disease, metabolic syndrome, diabetes, and obesity are also found in patients with oxidative stress.

In spite of free radicals harmful effects, one must understand that cellular oxygen species (ROS), are necessary with a moderate amount to protect our body in the mediation of antimicrobial infection, detoxification of potentially toxic compounds, and elimination.

Antioxidants are stable molecules that inhibit free radicals.

Free radicals such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, myeloperoxidase, superoxide dismutase, and glutathione peroxidase and antioxidants such as glutathione peroxidase, catalase, and superoxide dismutase (SOD) also act on specific oxidative pathways involving both pro-oxidant and antioxidant enzymes to maintain the healthy ratio in the body.

Normally, in a healthy individual, antioxidant enzymes produced by the liver are more than enough to counter levels of free radicals in the body. However, people with weakened immune system intake of dietary antioxidant or antioxidant supplements may be necessary.

On finding a natural ingredient for the prevention and treatment of chronic diseases, scientists examined the antioxidant contents in flowers of wild specimens of European elder (Sambucus nigra L.),

Elder or Common Elder, is a shrub or small tree of the genus Sambucus of 30 species, belonging to the family Adoxaceae, native to the temperate-to-subtropical regions of both the Northern Hemisphere and the Southern Hemisphere.

The herb has been used in traditional and herbal medicine to treat constipation, colic, diarrhea, colds, flu, bronchial and upper-respiratory, irritation of the skin, rheumatism, etc.

According to tested analysis,
* Flowers of wild specimens of European elder (Sambucus nigra L.), was relatively rich in elements K, Ca, Cu, Rb, and antioxidants, without accumulating heavy metals potentially bioavailable in the soil.

* The content of Fe, Cr, and Zn in elderflowers was revealed; the metal quantities were below levels harmful to humans.

* Furthermore, flowers from the city center exhibited higher antioxidant and radical scavenging capacities compared to plants from the areas of little traffic.

* Most importantly, the antioxidant parameters were negatively correlated with the silty fraction content and positively with the potentially bioavailable levels of Ti and Mn in soils and increased with the amount of Rb in the flowers.

 Based on the results, researchers suggest, "...for the first time that the urban specimens of wild S. nigra can perform as a local source of beneficial flowers providing cost-effective support in disease prevention and treatment".

Taken altogether, Elder (Sambucus) with rich antioxidants and metal content may be considered an antioxidant remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Selected metal content and antioxidant capacity of Sambucus nigra flowers from the urban areas versus soil parameters and traffic intensity by Topolska J1, Kostecka-Gugała A2, Ostachowicz B3, Latowski D. (PubMed)

Herbal Ashwagandha Improves Fertility in Men

By Kyle J. Norton

Infertility is a reproductive disease characterized by the failure to produce a pregnancy after 12 regular unprotected sexual intercourse, including pregnancy that can not be carried to term.

Infertility is very common in the US, approximately 10% of women or 6.1 million, ages 15-44 have difficulty getting pregnant or staying pregnant, according to the Centers for Disease Control and Prevention (CDC).

Believe it or not, only a very small number of such group are seeking help from the professionals.

In men, age, pesticide and chemical exposure, drug use, radiation, pollution, cigarette or marijuana smoke, heavy alcohol consumption may be some risk factors for the onset of infertility.

In fact, some unfertilized women and men sometimes ago are fertile. However, here are some reasons that have found to increase the risk of infertility in the Western world, including
* Persuade a personal career, before having children.
*Try to be financial stability before having children.
* Too young to be a parent, raising a child needs efforts, time and money.
* Enjoy the couple childless years before committing.

Some researchers suggested that the widespread obesity in North America may be the major factors correlated to the increased infertile rate over the past few decades.

Dr. Nicole O. Palmer the lead scientist in the concern of obesity in the risk of men infertility, wrote, "Obesity has detrimental influences on all systems, including reproductive health. The prevalence of obesity in infertile women is high, and it is well known that there is an association between obesity and infertility".

And, "Recent data has shown that male obesity also impairs offspring metabolic and reproductive health suggesting that paternal health cues are transmitted to the next generation with the mediator mostly likely occurring via the sperm.".

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of infertility, researchers examined beneficial effects induced by oral intake of the Withania sominifera (Ashwagandha) on semen quality of infertile men.

Based on the tested analysis, oral intake of Ashwagandha roots only improved sperm count and motility, and regulate reproductive hormone levels. but also inhibited the lipid peroxidation associated with the risk of infertility.

In a molecular perspective, oral intake of Ashwagandha roots inhibited the mitigation of oxidative stress and pathways involved in hormonal imbalance by enhancing the interaction of different endocrine glands to improve male fertility.

More precisely, Ashwagandha roots improved men fertility by mitigating risk factor-that cause the onset of men infertility.

In stress-induced male infertility on selected normozoospermic but infertile individuals (N = 60) that: divided into normozoospermic heavy smokers (N = 20), normozoospermic under psychological stress (N = 20) and normozoospermic with infertility of unknown etiology (N = 20).

Compared to Normozoospermic fertile men (N = 60), root powder of W. somnifera at a rate of 5 g/day for 3 months showed a strong effect in the treatment of stress-related infertility by improving the level of anti-oxidants and overall semen quality.

Root powder of W. somnifera treatment also resulted in pregnancy in the partners of 14% of the patients.

Taken altogether, Ashwagandha may be considered a functional herb for the treatment of male infertility, pending to the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Role of Withania somnifera (Ashwagandha) in the management of male infertility by Sengupta P1, Agarwal A2, Pogrebetskaya M3, Roychoudhury S4, Durairajanayagam D5, Henkel R. (PubMed)
(2) Withania somnifera Improves Semen Quality in Stress-Related Male Fertility by Mahdi AA1, Shukla KK, Ahmad MK, Rajender S, Shankhwar SN, Singh V, Dalela D. (PubMed)
(3) Impact of obesity on male fertility, sperm function and molecular composition by Nicole O. Palmer, Hassan W. Bakos, Tod Fullston, and Michelle Lane. (PMC)

Devil's claw (Harpagophytum procumbens) May Induce Interaction with Drugs When Used for the Treatment of Neurological Disorders

By Kyle J. Norton

Neurological disorders are medical conditions characterized by any disorder of the nervous system caused by structural, biochemical or electrical abnormalities.

There are many forms of neurological disorders. The most common types of the disease include neurodegenerative disease, such as Alzheimer's disease (AD) and Parkinson's disease, epilepsy. multiple sclerosis and Migraines.

According to the Medical press, globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy, etc) has increased substantially over the past 25 years.

These may be results of over 25 years of economic expansion that have increased the living standard of billion of people in the Southeast Asian region.

The WHO in the evaluation of neurological disorder wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".

Where one DALY represents the loss of the equivalent of one year of full health.

Believe it or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease and stroke.

Alzheimer's disease (AD) is a most common neurodegenerative disease in the elderly in the Western world, associated with the worsening of memory, thinking and behavior that severe enough to affect language communication, memory, lifelong hobbies or social life

On finding a natural ingredient for the prevention and treatment of neurodegenerative diseases, scientists examined the neuroprotective effects of Devil's claw.

Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa. 

The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc.

According to the active ingredients studied in laboratory and clinical settings, Devil's claw showed a promising natural therapeutics with anti-oxidative and anti-inflammatory salutations in protecting neuron integrity.

However, despite the promising and safe therapeutic benefits of CAM/herbal medicines, including Devil's claw, there exists a possible risk when combining them with prescription drugs.

In other words, Devil's claw may interact with drugs that have shown changes in blood pressure, hepatotoxicity, seizures, etc. when used in a combination.

Based on the results, researchers suggest, "Certainly, extensive work is needed to make sure that patients should take a regimen of protective and restorative therapy under an experienced healthcare professional".

Taken altogether, Devil's claw may be considered a remedy for the treatment of neurological disorders, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural or Plant Products for the Treatment of Neurological Disorders: Current Knowledge by Parvez MK. (PubMed)