Devil's Club (Oplopanax horridus) Processes Anti Diabetes Effects in Vitro and Vivo

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas inability to produce enough insulin, because of slowly die-off of insulin-producing cells in the pancreas.

LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.

Therefore, LADA shares the same risk factors and symptoms similar to those types 1 and 2 diabetes.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.

Devil's Club is a large shrub, genus Oplopanax, belonging to the family Aralioideae, native to the cool moist forests of western North America. 

The herb has been used in traditional and herbal medicine as Adaptogen, Antipyretic, Pain Reliever, Antitussive, Antibacterial agent and to treat Arthritis, Diabetes, Colds, Cough, Sore throat, Chest congestion, Stomach pain, Constipation, Gall stones, Influenza, Cancer, etc.

On finding a natural and potential compound for the treatment of chronic low-grade inflammatory diseases, researchers examined the anti-diabetic activity of ginsenoside Rb(3) found in Devil's club in a model of alloxan-induced diabetic mice.

The study included alloxan-induced diabetic mice that were treated with ginsenoside Rb(3) for 2 weeks at doses of 5 mg/kg, 15 mg/kg and 25 mg/kg.

According to the results of the experiment

In vivo
* After 2 weeks of treatment of ginsenoside Rb(3), the fasting blood glucose levels of DG 15 and DG 25 were respectively reduced by 36.70% and 37.50% compared to the control group. 

* At a dose of 25 mg/kg, oral glucose tolerance was significantly improved compared to the control group (P < 0.05).

*Furthermore, The AUC decreased by 34.47% (from 2442 ± 291 mmol·min/L to 1600 ± 109 mmol·min/L). Both food intake and water intake were remarkably lowered without alternating the bodyweight of diabetic mice.

* More importantly, the injury of the pancreas was repaired by the administration of ginsenoside Rb(3).

In vitro

* At the concentrations of 100 and 200 µM, ginsenoside Rb(3) increased glucose consumption in C2C12 myotubes by 76.83% and 97.20%, respectively, compared to the control group.

Collectively, researchers wrote, " our results showed that ginsenoside Rb(3) reduced fasting blood glucose level, food intake, water intake, improved oral glucose tolerance, and repaired injured pancreas tissues of alloxan-induced diabetic mice".

Taken altogether, Devil's club may be considered a remedy for the treatment of diabetes, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice by Bu QT1, Zhang WY, Chen QC, Zhang CZ, Gong XJ, Liu WC, Li W, Zheng YN. (PubMed)

Oleanolic Acid, Processes Anti-Gastric Cancer In Vitro

By Kyle J. Norton

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

Gastric/Stomach cancer is a chronic condition characterized by irregular cell growth in the tissues of the stomach.

Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.

However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.

At this stage, most patients with gastric cancer may experience symptoms of severe abdominal pain caused by the suppressing of the oversize tumor on the nerve cells, or vague discomfort in the abdomen, usually above the navel, particularly heartburn and indigestion, accompanied by general symptoms shared with other types of cancer.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.

Common sites metastases of gastric cancer are liver (48%), peritoneum (32%), lung (15%), and bone (12%).

The most common causative risk factor of gastric cancer is infection with a common bacteria, H. pylori, which were found to cause ulcers and Inflammatory gastritis,.

Oleanolic acid is a phytochemical in the subclass of Triterpenoid, belonging to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.

On finding a potential plant that processes anti-cancer activity researchers examined the effect of a
synergism of cisplatin-oleanolic acid on colon cancer.

According to the results of the analysis of cancer cell membrane (CM) decorated calcium carbonate (CC) hybrid nanoparticles (HN) for the co-delivery of cisplatin (CDDP) and oleanolic acid (OA),

* The -prepared DDS was core-shell structured and well-dispersed nanoparticles with a size around 100 nm.

* The HN/CDDP/OA showed high stability and biocompatibility with pH-responsive drug release. 

* The CM modification in HN also demonstrated a highly elevated tumor-homing nature than barely decorated calcium carbonate (CC).

* HN/CDDP/OA in the treatment of gastric cancer (MGC-803 cell line) showed better performance than mono systems with enhanced apoptosis and capable of reversing multidrug resistance (MDR) of cancer cells.

Taken altogether, Oleanolic acid may be considered a remedy or the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Synergism of cisplatin-oleanolic acid co-loaded hybrid nanoparticles on gastric carcinoma cells for enhanced apoptosis and reversed multidrug resistance by Li D1, Cui R2, Xu S1, Liu Y. (PubMed)

Ursolic acid Protects Diabetes Against Kidney Injury in Vivo

By Kyle J. Norton

Diabetic kidney disease is a type of kidney disease caused by diabetes.
Kidneys, a pair of the bean-shaped organ in the human body not only filter out blood but also balances the body fluids by eliminating them and removes them through urinary secretion.

Additionally, the kidney accompanied by the liver and skin form also detoxes the toxins in the body.

Kidney disease is a medical condition associated with a gradually reduced function of the kidney.

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Renal protection is a strategy that protects the kidney against injury or damage. In other words, renal protection is a process that maintains the function of the kidneys.

The most common kidney injury is associated with scar tissues forming in the kidneys.

Renal fibrosis is a condition of abnormal healing of the kidney tissues after injury, caused by the formation of scars in the kidney.

Renal scarring has been found to gradually reduced the renal function, leading to end-stage renal failure, depending on the severity and the area of scarring forming.

Patients at the end stage of renal failure may require dialysis or kidney transplantation.

Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness

Ursolic acid is a phytochemical in the subclass of Triterpenoid, belongings to the group of Terpenes found abundantly in apples, basil, bilberries, cranberries, peppermint, lavender, oregano, hawthorn, prunes., etc.

On finding a potential phytochemical for the treatment of kidney diseases, researchers examined the effects of ursolic acid (UA) mitigating renal inflammation, oxidative stress, and fibrosis.

The study included db/db mice that were divided randomly into a diabetic nephropathy (DN) group and a UA treatment group.

According to the analysis,
* UA treatment effectively reduced the body weights and blood glucose levels of db/db mice (p<0.05) as well as the urinary albumin/creatinine ratio (p<0.05).

* UA significantly improved the renal tissue lesions and glomerulosclerosis index of the db/db mice.after treatment (p<0.01).

* UA treatment also significantly lower expression levels of proteins associated with kidney injury and pro-inflammatory cytokines IL-1β and IL-18 in renal tissues, compared to the DN group.

In other words, researchers said, "UA alleviated renal damage in type 2 diabetic db/db mice by downregulating proteins in the ARAP1/AT1R signaling pathway to inhibit extracellular matrix accumulation, renal inflammation, fibrosis, and oxidative stress.".

Taken altogether, ursolic acid may be considered adjunct therapies in the treatment of diabetic kidney injury, pending to the confirmation of the larger sample size and multicenter human study.

Intake of ursolic acid in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway by Ma TK#1, Xu L#1,2, Lu LX#1,3, Cao X1, Li X1, Li LL1, Wang X4, Fan QL. (PubMed).

Pinto beans (Phaseolus) Promotes Gastrointestinal Digestion

By Kyle J. Norton

The digestive system consists of the gastrointestinal tract and other parts of the accessory organs of digestion including the tongue, salivary glands, pancreas, liver, and gallbladder), involved in the function of breaking down food into smaller and smaller components then absorbed before passing them as nutrients and fluids to the body.

In other words, the digestive system includes gastrointestinal tract (GI), liver, pancreas, and gallbladder with a healthy function of breaking down food into nutrients and fluids for the body's need.

Gastrointestinal diseases are the conditions of the digestive system associated with the disorders involving the gastrointestinal tract, including the esophagus, stomach, small intestine, large intestine, and rectum.

The most common causes of gastrointestinal diseases are a bacterial or viral infection, inflammation, poor circulation of the intestines, muscle dysfunction, gallstones, stress, particularly long-term use of anti-inflammatory drugs. However, gut microbiota, a community of microorganisms living in the gastrointestinal tract has been found to induce a significant effect on digestive health if imbalanced,

Digestion is a process of the digestive system by breaking out down food after intake for nutrients through mechanical and enzymatic action.

Indigestion, on the other hand, is symptoms of another digestive disease, including GERD. Most cases of indigestion not caused by underlying diseases can be resolved quickly.

People with indigestion experience symptoms differently. Some may feel the symptoms of occasionally while others may feel often and daily.

There are a number of risk factors associated with digestive disorders including bacterial and/or viral infection, inflammation, lactase deficiency, anti-inflammatory drugs and certain conditions such as ruptured or perforated organs, muscle dysfunction, gallstones.

However, some researchers suggested that there is a strong correlation between the risk of digestive disorders in obese patients.

Conventional medicine used for the treatment of gastrointestinal disorders is depending on the disease that triggers the disorder.such as antibiotics for bacterial infection, painkillers for stomach pain.

On finding a natural ingredient for the prevention and treatment of digestive diseases, scientists examined the effects of angiotensin I-converting enzyme (ACE)-inhibitory peptides released from thermally treated Phaseolus vulgaris (pinto) in gastrointestinal digestion.

Where Angiotensin-converting enzyme (ACE) inhibitors play a critical role to widen or dilate blood vessels.

Pinto bean is also known as common bean, genus Phaseolus and the family Fabaceae. The legume has a mottled appearance of darker reddish-brown spots on a lighter brownish beige background, thus appearing painted or spotted.

According to tested analysis,
* The <3 kDa fraction of the post pancreatic sample showed high ACE-inhibitory activity (IC50 = 105.6 ± 2.1 μg of peptides/mL).

* Three fractions isolated from the peptides, showed the highest response for the ACE-inhibitory activity.

More precisely, the chemical compounds that exerted the ACE-inhibitory activity were hydrophobic amino acid, (iso)leucine or phenylalanine, or proline.

Taken altogether, pinto beans as be considered ACE inhibitors for the improvement of gastrointestinal digestion, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Identification of ACE-inhibitory peptides from Phaseolus vulgaris after in vitro gastrointestinal digestion by Tagliazucchi D1, Martini S1, Bellesia A1, Conte A. (PubMed)

Gamma-linolenic Acid Ameliorates the Symptoms of Diabetic Neuropathy

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.
Diabetic neuropathy is a complication of patients with diabetes associated with nerve damages, ranging from pain and numbness in your legs and feet to problems with your digestive system.

Most cases of diabetic neuropathy are involved in diabetics who have a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart.

Diabetic neuropathy can be classified into 4 main types, including.

* Peripheral neuropathy is the most common type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms.

* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs and eyes.

* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks or legs.

* Mononeuropathy, or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso) or leg.

The exact causes of diabetic neuropathy are totally depending on the type of neuropathy. However, damage of nerves and blood vessels in the affected area has been found to induce by overtime, uncontrolled high blood sugar.

Gamma-linolenic acid is a phytochemical in the group of Omega-3, 6,9 fatty acids, belongings to the class of Lipids, found abundantly in evening primrose, borage, blackcurrant, etc.

On finding a potential plant that processes anti-diabetic activity, researchers examined the effect of gamma-linolenic acid on diabetic complications of neuropathy.

A multicenter, parallel-group, double-blind, double-dummy, randomized, noninferiority joint study include the evaluation of the efficacy and safety of γ-linolenic acid (GLA) relative to α-lipoic acid (ALA) over a 12-week treatment period in type 2 diabetes mellitus (T2DM) patients with painful diabetic peripheral neuropathy (DPN) was conducted.

According to the results of the analysis of 100 T2DM patients between 20 and 75 years of age who had painful DPN and received either GLA (320 mg/day) and placebo or ALA (600 mg/day) and placebo for 12 weeks,

* There was a significant decrease in the mean visual analog scale (VAS) and the total symptom scores (TSS). scores compared to baseline in both groups, but there were no significant differences between the groups.

* The treatment difference for the VAS (95% confidence interval [CI]) between the two groups was -0.65 (-1.526 to 0.213) and the upper bound of the 95% CI did not exceed the predefined noninferiority margin (δ₁=0.51).

* For the TSS, the treatment difference was -0.05 (-1.211 to 1.101) but the upper bound of the 95% CI crossed the noninferiority margin (δ₂=0.054).

* There were no serious adverse events associated with the treatments.

Collectively, researchers said, "GLA treatment in patients with painful DPN was noninferior to ALA in terms of reducing pain intensity measured by the VAS over 12 weeks".

Taken altogether, gamma-linolenic acid may be considered a functional food for reducing the painful diabetic neuropathy, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial by Won JC1, Kwon HS2, Moon SS3, Chun SW4, Kim CH5, Park IB6, Kim IJ7, Lee J8, Cha BY9, Park TS. (PubMed)

Fermented Soy, the Natural Antioxidant

By Kyle J. Norton

Antioxidants are stable molecules that inhibit free radicals.

Total antioxidant capacity (TAC) is a measure that assesses the antioxidant status and evaluates the antioxidant response against the free radicals produced in a patient.

Free radicals are unstable atoms with an unpair of electrons on the out ring of molecules. Therefore, in order for them to become stable, they constantly seek to donate or intercept the electron from other stable atoms, leading to a chain reaction that can not be stopped until all unpaired electrons are paired or inhibited by antioxidants.

In spite of free radicals harmful effects, one must understand that cellular oxygen species (ROS), are necessary with a moderate amount to protect our body in the mediation of antimicrobial infection, detoxification of potentially toxic compounds, and elimination of cancerous and other life-threatening cells through cytotoxicity.

Free radicals such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, myeloperoxidase, superoxide dismutase, and glutathione peroxidase and antioxidants such as glutathione peroxidase, catalase, and superoxide dismutase (SOD) also act on specific oxidative pathways involving both pro-oxidant and antioxidant enzymes to maintain the healthy ratio in the body.

Normally, in a healthy individual, antioxidant enzymes produced by the liver are more than enough to counter levels of free radicals in the body. However, people with weakened immune system intake of dietary antioxidant or antioxidant supplements may be necessary.

Oxidative stress is a medical condition caused by the unbalanced ratio of the levels of free radical and antioxidant enzymes produced by the host.

In fact, free radicals exist everywhere including the airs we breathe, the thing we eat and the environment we contact, particularly, cell metabolism in the body.

Epidemiologically, overexpression of free radicals has been found to induce damage to the cell, lipid, proteins, and alternation of cell DNA, leading to chronic diseases, such as cardiovascular diseases, diabetes and particularly, cancer.

Fermented soy products are diverse varieties of soy food that are made from fermented soybeans, including miso, natto, tempeh, and soy sauce.


On finding a potential plant that processes anti-oxidative stress activity, researchers examined the relationship between in vitro antioxidant capacity of soy sauces and its impact on lipid oxidation in raw and cooked beef patties during 10 days of refrigerated storage.

According to the results of the analysis of 3 commercial soy sauces including industrially fermented soy sauce (IS), traditionally fermented Korean soy sauce (KS), and mixed soy sauce (MS),

* In vitro antioxidant capacity, KS showed the highest total phenol content, whereas IS and MS had a higher Fe2+ chelating activity than KS (P < .05).

* Heat treatment decreased total phenol content but increased Fe2+ chelating activity of soy sauces (P < .001).

* In both raw and cooked beef patties, the addition of IS or MS caused a lower 2-thiobarbituric acid reactive substances (TBARS) level than KS throughout the overall storage period (P < .05).

Collectively, researchers suggest, "the Fe2+ chelating activity of soy sauce may be one of the major mechanisms in preventing lipid oxidation in meat products".

Taken altogether, potato may be considered a functional food for the prevention and treatment of diseases associated with oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Relationship between the antioxidant capacity of soy sauces and its impact on lipid oxidation of beef patties by Ham YK1, Hwang KE2, Song DH3, Choi JH2, Choi YS4, Kim HW. (PubMed)

Herbal Enchinanea Enhances the Immune Response Against H9N2 Avian Influenza Virus

By Kyle J. Norton

Influenza, also known as the flu, is an infectious disease caused by an influenza virus.

There are 3 types of flu influenza: A, B, and C. the influenza virus A and B are considered seasonal flu that causes sniffling, aching, coughing, and running and stuffy nose and fever to over 20% of the general population.

Influenza virus types C tends to cause mild upper respiratory infections, similar to those of cold.

Healthy individuals who have influenza are usually recovered within one week.

However, people with immature and weakened immune system such as young children under age 5, adults older than age 65 residents of nursing homes and other long-term care facilities, chronic illnesses, such as asthma, heart disease, kidney disease, liver disease, and diabetes are not only associated with the risk of influenza but also increase the risk of influenza deadly complication.

Infection is a condition that caused the invasion of stimuli and micro pathogens, including viral infection.

A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.

Anti-viral effects are an act of certain substances to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection o\has been known to carry over some different stage, after successfully attaching to the host cell, the virus to release its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

H9N2 is a subtype of the species Influenza A virus. The H9N2 influenza strain had caused illness in several children aged nine months to 5 years in Hong Kong with the latest occurring in December 2009, according to statistics.

Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of viral diseases, researchers examined the effect of Immulant® (IMU) (a commercial product based on Echinacea and Nigella sativa) on stress-induced by dexamethasone (DEX) in chickens vaccinated (VAC) against the H9N2 avian influenza virus (AIV-H9N2).

The study included vaccinated chickens (at 10 days of age) that were injected daily with DEX for three days pre-vaccination and for three days pre-challenge and orally administered 1% IMU for 6 weeks post-vaccination (PV), following by the challenge of intranasal AIV-H9N2 at 28 days PV.

According to the analysis of the results of serum, blood, tracheal and cloacal swabs and tissue samples were collected in the 1st and 4th weeks,

* The formula showed significant changes (P ≤ 0.05) in oxidative stress and antioxidant biomarkers (malondialdehyde, nitric oxide, and reduced glutathione), hematological and immunological parameters, final live weights, relative organ weights and histopathological lesions between the VAC+DEX group and the VAC group.

* IMU significantly increased protection rates post-challenge, HI antibody titers and heterophil phagocytic activity and decreased DEX-induced stress and virus shedding titers.

In other words, IMU inhibited the initiation and progression of AIV-H9N2 in the induction of infection through several antiviral mechanisms.

After talking about other factors into account, researchers said, "oral administration of 1% IMU for six weeks can enhance the immune response after AI-H9N2 vaccination and reduce the pathogenicity of infection in stressed chickens".

Taken altogether, herbal Enchinanea used alone or combined with other medicines may be considered adjunct therapies in the treatment of AIV-H9N2 infection, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparative immune response and pathogenicity of the H9N2 avian influenza virus after administration of Immulant®, based on Echinacea and Nigella sativa, in stressed chickens by Eladl AH1, Arafat N2, El-Shafei RA3, Farag VM4, Saleh RM5, Awadin WF. (PubMed)