Thursday, 2 January 2020

Omega-3 Fatty Acids May Be Used for the Treatment of Crohn's disease (CD)

By Kyle J. Norton

Inflammatory bowel disease is a condition characterized by long term inflammation of the gut. The disease affects over 1.6 million Americans today.

The most common types of IBD are
*Crohn’s disease (CD) is an inflammation of any part of the digestive tract. Most cases of CD affect the tail end of the small intestine.

* Ulcerative colitis is an inflammation of the large intestine.

* Crohn's disease is a type of inflammatory bowel disease caused by inflammation in the gastrointestinal tract.

The exact cause of Crohn's disease is not identified. However, some researchers suggested that people with the compromised immune system and genetic preposition are prone to the disease onset compared to people who do not

The most common symptoms of Crohn's disease are abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.

Risk factors of Crohn's disease include aging, family and person history, ethnicity, smoking and long-term use of Nonsteroidal anti-inflammatory medications.

Conventionally, most cases of CD are treated by anti-inflammatory medications, corticosteroids, immunomodulators, and antibiotics.

According to the statistics by Crohn's & Colitis Foundation, the total number of new cases of Crohn's disease diagnosed each year was 10.7 per 100,000 people.  In other words, approximately 33,000 new cases are diagnosed each year. 


Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic inflammatory diseases, researchers examined the omega-3 supplementation by oral capsule for patients with Crohn's disease (CD).

The study included a total of 6 patients with CD in remission who participated in this open-label clinical trial and received one bottle (100 ml) of the test formulation (IMARK S®) daily for 28 days. After a 1-month washout period, patients ingested two bottles of the formulation daily for another 28 days.

According to the results of the anthropometric and blood tests,
* There were no side effects with the quantity of the injection.

* The application did not alter the body weight and body-mass index in the participants.

* Most importantly, according to the CD activity index, participants showed a decrease in the scores after ingested one bottle of the formulation.

  Based on the findings, researchers said, "Supplementation with an omega-3 emulsifying formulation can be safe and useful for maintaining remission in patients with CD and warrants further studies".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of Crohn's disease (CD), pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Safety of Emulsifying Lipid Formulation Containing Omega-3 Polyunsaturated Fatty Acids for Patients with Crohn's Disease by Yasueda A1, Shinzaki S2, Iijima H2, Mizushima T3, Nishimura J4, Hiyama S5, Ohno S1, Ito T. (PubMed)

Beta-Sitosterol inhibits Oxidative Stress by Promoting Antioxidant Activity

By Kyle J. Norton

The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.

Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of diseases associated with oxidative stress, researchers examined the beta-sitosterol (BS), a plant sterol antioxidant activity.

In vitro, HT22 cells and primarily cultured hippocampal cells induced oxidative stress by glucose oxidase (GOX) incorporate BS into the plasma membrane, prevented GOX-induced oxidative stress and lipid peroxidation.

Furthermore, incorporation of BS into the cell membrane increased the PI3K activity in the promotion of cellular function and recruitment of PI3K to lipid rafts.

Additionally, the levels of p-GSK3beta also in the promotion of cell integrity were also enhanced by the application of BS against the onset of oxidative stress.

Based on the evidence, researchers said, " ...the results provide a better understanding of the beneficial effects of these BS-enriched nutrients on neurodegenerative diseases such as AD".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of diseases associated with oxidative stress, including AD, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Incorporation of beta-sitosterol into the membrane increases resistance to oxidative stress and lipid peroxidation via estrogen receptor-mediated PI3K/GSK3beta signaling by Shi C1, Wu F, Zhu XC, Xu J. (PubMed)

Organic Cabbage Inhibits the Risk of Gastric Cancer in Vitro

By Kyle J. Norton

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

Gastric or stomach cancer is a chronic condition characterized by irregular cell growth in the tissues of the stomach.

Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.

However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.

Gastric adenocarcinoma is a type of cancer that arises from the glands in the mucosa, including
* Superficial spreading
It is an early stage of cancer and tends to be less aggressive or ulcer.

* Polyploid
Cancer grows in a pattern like a polyp and is less aggressive.

* Infiltrating
If cancer grows in infiltrating pattern into the stomach wall and more aggressive.

* Linitis plastica
Cancer grows diffusivity throughout the whole wall of the stomach.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find a natural food for the prevention of cancers, researchers examined the effect of cabbage extract on gastric cancer cells.

According to the tested differentiation, organic fresh cabbage contained significantly less total flavonoids in both years of experiments compared to the conventional one, including several flavonoid compounds, total chlorophylls, carotenoids, nitrites, and nitrates.

Furthermore, the organic sauerkraut juice contained significantly more total polyphenols (5.39 ± 0.22 mg/100 g FW and 9.05 ± 1.10 mg/100 g FW) and several flavonoids compared to the conventional one.

Compared to only CONV sauerkraut juice produced with the highest N level of fertilization induced a statistically significant increase in the level of necrosis of human stomach gastric adenocarcinoma cell line AGS, all sauerkraut juice exerted anti-apoptotic activity in gastric adenocarcinoma cells.

Taken altogether, cabbage processed abundantly bioactive compounds including nitrites, and nitrates may be considered a remedy for the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Nutritive Value of Organic and Conventional White Cabbage (BrassicaOleracea L. Var. Capitata) and Anti-Apoptotic Activity in Gastric AdenocarcinomaCells of Sauerkraut Juice Produced Therof by Hallmann E1, Kazimierczak R1, Marszałek K2, Drela N3, Kiernozek E3, Toomik P4, Matt D5, Luik A5, Rembiałkowska E. (PubMed)

Tuesday, 31 December 2019

The Health Benefits of Omega 3 Fatty Acids

By Kyle J. Norton

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the prevention of diseases, researchers examined the myriad health benefits of omega-3 PUFAs.

According to the search of epidemiological studies, omega-3 PUFAs exerted a strong activity against the risk and treatment of
* Cardiovascular diseases
Cardiovascular disease is a group of conditions triggered by the abnormal function of the heart and blood vessels abnormality.

The 3 most common forms of cardiovascular disease in North America are coronary artery disease, peripheral artery disease, and carotid artery disease caused by plaques build-up of plaque in the arteries that supply blood to the heart, the arms and legs, and the brain, respectively.
* Diabetes
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

Most common types of diabetes are
**Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

** Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate glucose due to either cell in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

* Cancer
Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.

The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
* Alzheimer's disease
Alzheimer's disease is a brain disorder correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer. Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal. 

According to statistics, over 25 million people in the world today are affected by dementia and most are suffering from Alzheimer's disease.

* Dementia
About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability that is severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

* Depression
Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness. Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself.

Furthermore, omega 3 fatty acids improved fetal health including slightly increase a baby’s weight at birth and the length of time the baby is in the womb, both of which may be beneficial. Breast milk contains DHA.

However, researchers explained, "there are also some controversies about their efficacy and certain benefits to human health".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the promotion of health benefits, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits by Shahidi F1, Ambigaipalan P. (PubMed)

Beta-Sitosterol, the Potential Anti-Skin Cancer Supplement

By Kyle J. Norton

Skin, a large organ that forms the out layers of our body has a serval layer of ectodermal tissue to protect the underlying muscles, bones, ligaments and internal organs against foreign pathogenic invasion.

Skin cancer is a medical condition of uncontrolled growth of abnormal skin cells and often detected at an early stage.

Most cases of primary skin cancer start in the cell on the surface of the inner ling of the skin. At the advanced stage, the cancerous cells can travel a distance away from the skin to infect other healthy tissue and organ through blood and fluid circulation.

There are 3 main types of cells in the top layer of the skin (called the epidermis):
Squamous cells, Basal cells, and Melanocytes.

Long-term cumulative sun exposure is one of the major causes of basal cell and squamous cell skin cancer. Exposure to ultraviolet (UV) radiation is the leading cause of melanoma.

Certain risk factors that make some people susceptible to the development of skin cancer than others, include the increase in age, weakened immune system, gender, skin tone, genetic preposition, and family history.

According to the statistics, skin cancer is the most common cancer in the US. one in five Americans will develop skin cancer in their lifetime.

Every day, approximately 9,500 people in the U.S. are diagnosed with skin cancer due to a misunderstanding of the health benefits and risk of sun and tanning exposure.

Most common symptoms at the early stage, are a large brownish spot with darker speckles, a mole that changes in color, size or feel or that bleeds, a small lesion with an irregular border and portions that appear red, pink, white, blue or blue-black.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of cancer, researchers compared the effects of Betulinic acid (1), betulinic acid-3-acetate (2), 3-acetyl betulin aldehyde (3), oleanolic acid-3-acetate (4), 3-β-hydroxy-28,19-β-olenolide (5), and β-sitosterol (6) were isolated from Platanus orientalis on skin cancer cells.

According to the chemical analysis, The (1 ) is the most abundant component (4.63%) compared to the least of the (5) (0.017%) the least.

All isolated compounds showed a significant cytotoxic effect against human keratinocyte, mouse melanoma, and human skin epithelial carcinoma cancer cells according to the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.

In other words, all compounds found in Platanus orientalis work synergistically against the skin cancer risk in vivo.

Taken altogether, beta-sitosterol may be considered supplements for the prevention of od skin cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A validated high-performance thin-layer chromatography method for the identification and simultaneous quantification of six markers from Platanus orientalis and their cytotoxic profiles against skin cancer cell lines by Khan I1, Sangwan PL, Dar AA, Rafiq RA, Farrukh MR, Dhar JK, Tasduq SA, Koul S. (PubMed)

Tocopherols Protect the Heart Against the Risk of Cardiovascular Diseases CVD

By Kyle J. Norton

Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.

In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, which causes damage to the heart tissue and reduced function of the arteries.

In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.

According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.

Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease is such a risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.

According to statistics, heart disease is the second leading cause of death, claiming more than 48,000 lives every year.in Canada.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocotrienol on oxidative stress and inflammation in the manifestation of aging-related cardiovascular disease.

According to the analysis,  vitamin E supplement demonstrated significant activity in reducing the expression of oxidative stress induced by chronic inflammation.

More precisely, the efficacy of vitamin E that decreases the oxidative stress-induced cardiovascular disease was attributed to the presence of chemical compounds tocotrienols and tocopherols

More precisely, tocopherols, a class of Vitamin E compounds showed a lesser antioxidative and anti-inflammatory activity compared to those of tocotrienols (the other class of Vitamin E compounds), in ameliorating aging-related cardiovascular diseases and its associated morbidities.

Based on the results, researchers said, "the potential of tocotrienols in improving inflammation, dyslipidemia and mitochondrial dysfunction in aging-related cardiovascular diseases...".

Taken altogether, tocopherols may be considered a supplement for reducing the risk of cardiovascular diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tocotrienol is a cardioprotective agent against aging-associated cardiovascular disease and its associated morbidities by Ramanathan N1,2, Tan E3, Loh LJ3, Soh BS3,4,5, Yap WN. (PubMed)

Monday, 30 December 2019

Phytochemical Beta-Sitosterol, the Anti-Bacterial Remedy

By Kyle J. Norton

Bacteria is a type of biological cell consisted of a single cell with a simple internal structure. The most common diseases caused by bacteria are strep throat, urinary tract infections, and tuberculosis.

Infection is an inflammatory condition caused by a microbial invasion on body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

The most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.

Infection can be acute or chronic. In the acute phase of infection. The immune macrophages in the first line of defense stimulate the production of blood palette to cover the wound and pro-inflammatory cytokines to the site of the infection to kill off pathogens.

However, overproduction of pro-inflammatory cytokines in the acute phase of infection has also killed off or damage to the nearby healthy cells, leading to the formation of scars.

Symptoms of the acute infection include gastrointestinal discomforts, such as congestion vomiting or nausea, and diarrhea, short term joint or muscle pain, fever, headache, skin rash and cough, Some patients with acute infection also experience symptoms of swollen lymph nodes, an indication of the body is fighting infection.

In most cases in a healthy individual, depending on the size of the wound, the immune system can easily eradicate all foreign invaders and the wound is recovered within days and weeks.

In chronic infection, the symptoms are most vague or no specific symptoms, including bronchitis and asthma, persistent low-grade chronic joint and muscle pain, or swelling and the alternations between diarrhea and constipation, bloating, or heartburn, In other words, the symptoms are totally depended on the location of the low-grade inflammation.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers examined the antibacterial activity of compounds from the powder of root bark of Malva parviflora (Malvaceae).

According to the chemical analysis of the extracts with petroleum ether (b.p. 60–80 °C), chloroform and ethanol, the chloroform extract showed antibacterial activity against Staphylococcus aureus and Escherichia coli compared to the effect of the ethanolic extract against only S. aureus.

The chloroform extract inhibited the bacterial strain properties were characterized as β-sitosterol by physical properties, chemical test, spectral analysis (FTIR, NMR, and MS) and compared the data obtained from the literature.

In other words,  phytochemical β-sitosterol prompted a strong anti-bacterial activity of root bark of Malva parviflora (Malvaceae)

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of bacterial infectious diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Structure elucidation of β-sitosterol with antibacterial activity from the root bark of Malvaparviflora by Mesfin Medihin Ododo,1 Manash Kumar Choudhury,2 and Ahmed Hussen Dekebo. (PMC)