Saturday, 30 November 2019

Lycopene Inhibits the Onset of Chronic Bacterial Prostatitis, According to Studies

By Kyle J. Norton

Prostatitis is a condition associated with the inflammation of the prostate and the areas around the prostate.

Chronic bacterial prostatitis is a medical condition of prostatitis induced by a bacterial infection.

According to the statistics provided by the American Family Physician, approximately 8.2 percent of men in the US are living with prostatitis. The conditions account for 8 percent of visits to urologists, and up to 1 percent of visits to primary care physicians.

Believe it or not, in 2000, prostatitis has cost over $84 million, including the charge of diagnosis and treatment.

The most common symptoms of prostatitis are painful, difficult and/or frequent urinating, groin pain, rectal pain, abdominal pain and/or low back pain, fever, chills, and body aches.

In severe cases, patients may also experience symptoms of urethral discharge, painful ejaculation or sexual dysfunction and blood in the urine.

The exact causes of prostatitis are not identified, some researchers suggested that nerve damage in the lower urinary tract caused by surgery or trauma to the area has been found to induce prostatitis in patients.

Conventionally, most cases of prostatitis are treated by antibiotics in cases of infection, alpha-blockers to relax the bladder neck and the muscle fibers and anti-inflammatory medicine to ease pain and discomforts.

Dr. JAMES J. STEVERMER, the lead scientist in the treatment of chronic bacterial prostatitis at the University of Missouri–Columbia School of Medicine, wrote, "If the patient responds to therapy, antibiotics are continued for at least three to four weeks, although some men require treatment for several months. A patient who does not respond might be evaluated for chronic nonbacterial prostatitis, in which nonsteroidal anti-inflammatory drugs, alpha-blocking agents, anticholinergic agents or other therapies may provide symptomatic relief".



Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of prostatitis, researchers evaluated the efficacy and the safety of a combination of Serenoa repens, selenium and lycopene extract + bromelain and methylsulfonylmethane extract associated with levofloxacin in patients with chronic bacterial prostatitis (CBP).

The study included all patients with a clinical and instrumental diagnosis of CBP, admitted to a single Urological Institution from March to June 2015 were enrolled in this phase III study. 

All selected patients were randomized into two groups, Group A (n=40)received levofloxacin 500 mg o.d. for 14 days associated with lycopene and methylsulfonylmethane; Group B (n=39) received levofloxacin (500 mg o.d. for 14 days) only.

According to the results from the follow-up (T1), the NIH Chronic Prostatitis Symptom Index (CPSI), International Prostatic Symptom Score (IPSS) of group A were significantly lower compared to group B.
In other words, group A showed milder symptoms compared to group B.

Furthermore, the symptomatic and microbiological recurrence was also significantly lower in group A n=1) compared to group B (n=7).

Moreover, these change between groups was continued at the second follow-up visit (T2) observed by the questionnaire results.

Based on the findings, researchers said, "The combination of Serenoa repens, selenium, lycopene + bromelain and methylsulfonylmethane extracts improved the clinical efficacy of levofloxacin in patients affected by CBP without the development of side effects".

Taken altogether, lycopene found in tomato may be considered an adjunct therapy for the treatment of chronic bacterial prostatitis, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients by Cai T1, Tiscione D, Gallelli L, Verze P, Palmieri A, Mirone V, Bartoletti R, Malossini G. (PubMed)
(2) Treatment of Prostatitis by JAMES J. STEVERMER, M.D., M.S.P.H., and SUSAN K. EASLEY, M.D. (the University of Missouri–Columbia School of Medicine, Columbia, Missouri)

Cranberry Protects the Neurons Against β-Amyloid Aggregation

By Kyle J. Norton

Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, leading to the onset of Alzheimer's disease.

Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.

Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.

According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.

 Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.

More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.

Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.


Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia.

 Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of mental disorders, researchers examined the effect of cranberry supplementation on β-amyloid aggregation.

According to tested analysis, the cranberry protected the neurons by mediating Aβ toxicity alleviation required heat shock transcription factor (HSF)-1 rather than DAF-16 and SKN-1associated with cellular stress.

In other words, cranberry supplementation reduced Aβ toxicity induced brain cell stress by reducing the transactivity of HSF-1 in an IIS-dependent manner.

More precisely, HSF-1 plays a pivotal role in maintaining proteostasis, a process that regulates proteins within the cell in order to maintain the neuron cellular health involved in oxidative stress.

Based on the findings, researchers aid, "(cranberry) elucidated the mechanism whereby cranberry attenuated Aβ toxicity in C elegans and stressed the significance of proteostasis in the prevention of age-related diseases from a practical point of view.".

Taken altogether, cranberry may be considered a remedy for the treatment of AD, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 in Caenorhabditis elegans Model of Alzheimer’s Disease by
Hong Guo, Min Cao, Sige Zou, 4 Boping Ye,  and Yuqing Dong. (PMC)

Friday, 29 November 2019

Herbal Ashwagandha Balance the Ratio of Antioxidants and Free Radicals Against the Onset of Oxidative Stress

By Kyle J. Norton

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake dietary sources of antioxidants may be necessary.

Oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

Dr. Ercal N, the lead author in the study of the relation of toxic metals and oxidative stress, wrote, "antioxidants may play an important role in abating some hazards of heavy metals. In order to prove the importance of using antioxidants in heavy metal poisoning, pertinent biochemical mechanisms for metal-induced oxidative stress".

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound that processes the antioxidant activity, researchers examined  the acetylcholine esterase (AChE) inhibitory and antioxidant potential of Ashwagandha root extract (ARE

Ashwagandha root extract (ARE) in in-vitro and ex-vivo models showed a strong free radical scavenging effect by preventing protein degradation.

In rat lymphocytes, ARE pre-treatment not only protect the immune cells's integrity against s against H2 O2 -induced oxidative damage including DNA fragmentation and significantly decreased the activities of key antioxidant enzymes such as peroxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose-6-phosphate dehydrogenase.

Furthermore, the decreased and increased the content of glutathione and malondialdehyde induced by the injection H2O2 have also reversed,  indicating by the remedy to suppress hydrogen peroxide-induced oxidative stress.

Collectively, researchers said, "The study provides the scientific basis of pleiotropic functions of Ashwagandha".

Taken altogether, Ashwagandha may be considered a functional herb for the treatment of chronic diseases induced by oxidative stress, pending to the result of larger sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ashwagandha Root Extract Inhibits Acetylcholine Esterase, Protein Modification and Ameliorates H2 O2 -Induced Oxidative Stress in Rat Lymphocytes by Ajay Pal1 , Kandikattu Hemanth Kumar2 , Bharat Bhushan*1, Vinod Saharan (Pharmacogn J. 2017; 9(3):302-309A Multifaceted Journal in the field of Natural Products)
(2) Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage by Ercal N1, Gurer-Orhan H, Aykin-Burns N.(PubMed)

Herbal Coltsfoot(Tussilago farfara) Induces Expectorant Effect in Vivo

By Kyle J. Norton

An expectorant effect is a function that helps to cough up loosen mucus by increasing the water content.

Coughing is a natural reflex that clears the throat of mucus or foreign pathogens.
In other words,  frequent coughing may be a condition of infection caused by inflammation of the airway. 

An acute cough is short-term coughing that lasts for less than three weeks. Chronic coughing that lasts more than 3 weeks may be a condition of respiratory diseases, including asthma, allergies, gastroesophageal reflux disease (GERD), or bronchitis.

Phlegm produced in the lungs and lower respiratory tract is a type of mucus found mostly in acutely sick or longstanding health conditions patients.

Chronic mucus collected in the lungs has been associated with patients with tuberculosis (TB), pneumonia, a fungal infection, whooping cough early in life and measles.

Seriously, chronic mucus collected in the lungs increases a significant risk of further infections and more damage.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

The Modern Research Center for Traditional Chinese Medicine of Shanxi University, the expectorant effect of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae) examined the water extracts orally from flower bud and rachis that administrated to tested mice.


Mice selected to the study induced coughing by Ammonia showed a strong effect on significantly lengthened the latent period of cough, decreased cough frequency.

Furthermore, in expectorant evaluation, the phenolic compounds, organic acid, sugar, amino acid, terpene, and sterol were found to be the major contribution in enhancing tracheal phenol red output.

Additionally, in chemical analysis, the high concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds showed a significant antitussive and expectorant effects of Flos Farfara compared to flower rachis.

Dr. Li ZY, the lead scientist said, "These findings provide pharmacological and chemical evidence that only flower bud can be used as the antitussive and expectorant herbal drug".

Taken altogether, coltsfoot may be considered a remedy for loosening mucus, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice by Li ZY1, Zhi HJ, Xue SY, Sun HF, Zhang FS, Jia JP, Xing J, Zhang LZ, Qin XM. (PubMed)

Thursday, 28 November 2019

Turmeric Processes Anti-Metastatic Activity

By Kyle J. Norton

Cancer is a class of diseases characterized by the irregular cell growth on the body tissue, due to the alternation of cell DNA.

Most cases of cancer start in the cell on the surface of the inner lining tissue and do not exert any symptoms at the early stage.

At the later stage, the larger size tumor may press on the nearby blood vessels and nerve cells, causing localized severe bleeding and pain accompanied by the general symptoms of cancers, including the unintended weight loss, loss of appetite, fatigue and tiredness and gastrointestinal problems.

Most cancer cells at this stage can also travel a distance away from the original site to affect other healthy tissue and organs, leading to secondary metastasis.

Metastasis is the process to induce the development of secondary malignant growths at a distance from primary cancer.

Metastatic cancer also shares the characteristics of primary cancer. Breast cancer that spreads to the lung is called metastatic breast cancer, not lung cancer.

According to statistics, in 2018, approximately over1,700,000 cases of cancer were diagnosed worldwide. The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Believe it or not, some metastatic cancer may have an unknown primary origin or CUP, secondary cancer without a primary cancer site.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to discover a natural ingredient for the prevention of metastasis in cancer, researchers examined the effects of Furanodiene, a bioactive compound isolated from Curcuma wenyujin Y. H. Chen et C. Ling (C. wenyujin) on tumor metastatic activities.

According to the tested differentiation, low concentrations (5-25μM) of furanodiene inhibited adhesion, migration, and invasion of breast cancer cells, without inducing cytotoxicity, apoptosis and cell cycle arrest.

Furthermore, furanodiene also regulated the parameters such as the integrin αV expression, β-catenin expression, associated with the cell survival, migration, proliferation, differentiation, angiogenesis, and remodeling of the extracellular matrix in the modulation of the tumor metastasis process.

In MDA-MB-231 cells, furanodiene modulated the matrix metalloproteinase 9 (MMP-9) involved in tumor metastasis and cancer markers.

Based on the results Dr. Zhong Z, the lead scientist said, "furanodiene might be the primary contributor to the anti-cancer effects of volatile oil extracts, and it might be a good therapeutic target for highly metastatic breast cancer".

Taken altogether, turmeric processed a high amount of bioactive compound furanodiene may be considered supplements for the prevention of tumor metastasis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Furanodiene, a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro by Zhong Z1, Tan W1, Chen X2, Wang Y. (PubMed)

Chinese Sauerkraut, the Anti Hyperuricemia Functional Food

By Kyle J. Norton

Hyperuricemia is a condition of an excess of uric acid in the blood caused by reduced renal function.

The most common causes of hyperuricemia are genetics, insulin resistance, hypertension, hypothyroidism, obesity, diet, medications such as diuretics, and consumption of excess alcoholic beverages.

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in the blood, inducing joint inflammation.

The causes of gout are the result of high levels of uric acid in the body that can lead to the forming of crystals causes of inflammation due to your body can not get rid of uric acid or have made too much uric acid.

Reduced intake of meats and seafood and foods containing higher levels of uric acid, such as alcoholic beverages, especially beer, and drinks sweetened with fruit sugar (fructose) in patients with gout may be necessary.

According to the New York University School of Medicine/Langone Medical Center, the prevalence of gout and hyperuricemia has increased dramatically during the last several decades, to the point that gout is the most common inflammatory arthritis in the United States, affecting approximately 8 million Americans and contributing to great numbers of hypertension, chronic kidney disease, and cardiovascular disease.

The most common medication for the treatment of gout is Non-steroidal anti-inflammatory drugs (NSAIDs) by reducing pain and inflammation during an attack.

Chinese sauerkraut is a traditional Chinese pickled Chinese cabbage.

Depending on the regions, in Northern China,  Napa cabbages were traditional vegetables of choice to make Chinese sauerkraut.

In Southern China,  thick stalk varieties of Chinese mustard are preferred.

On finding the potential compound for the prevention and treatment of gout, researchers led by the Dalian Medical University investigated fifty-five lactic acid bacteria isolated from Chinese sauerkraut which have the ability to degrade inosine and guanosine, the two key intermediates in purine metabolism.

According to tested analysis, the strains DM9218 showed the best probiotic potential compared with other strains despite its poor bile resistance compared to strain DM9218-A which showed better resistance to 0.3% bile salt.

DM9218 has the highest probiotic activity similarity (99%) to those of Lactobacillus Plantarum WCFS1.

Furthermore, the strain DM9218-A showed a significant effect to inhibit the level of serum uric acid in the hyperuricemic rat.

Moreover, DM9218-A in The preventive treatment caused a greater reduction in serum uric acid concentration in hyperuricemic rats than the later treatment.

Based on the findings, researchers said, "DM9218-A may be a promising candidate as an adjunctive treatment in patients with hyperuricemia during the onset period of the disease. DM9218-A also has potential as a probiotic in the prevention of hyperuricemia in the normal population".

Taken altogether, Chinese sauerkraut processed a high amount of DM9218-A may be used as probiotics for the prevention and treatment of gout, pending to large sample size and multicenter study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Screening and characterization of purine nucleoside degrading lactic acid bacteria isolated from Chinese sauerkraut and evaluation of the serum uric acid-lowering effect in hyperuricemic rats by Li M1, Yang D1, Mei L2, Yuan L3, Xie A1, Yuan J. (PubMed)
(2) The Clinical trials and Studies of musculoskeletal disorders(MSDs) - Gout: The Causes by Kyle J. Norton

Wednesday, 27 November 2019

Broccoli or Broccoli sprouts Do Not Cause Thyroidial Toxicity Induced-Thyroid Dysfunction or Thyroid Autoimmune Disease

By Kyle J. Norton

Thyroid disease is a medical condition that causes a malfunction of the thyroid.

Hyperthyroidism is a condition in which the thyroid gland is overactive and produces too much thyroid hormones. 

The most common symptoms of hyperthyroidism are excessive sweating, heat intolerance, increased bowel movements, shaking, nervousness, agitation, anxiety, rapid heart rate, palpitations, irregular heart rate, weight loss, fatigue, weakness...

Hypothyroidism is a condition in which the thyroid gland is underactive and produces very little thyroid hormones.

Symptoms of hypothyroidism are depended on the severe stage of the disease. as it progresses slowly over years such as weight gain and fatigue, vitiligo and alopecia areata, chronic constipation, urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin, alopecia periorbital edema, amenorrhea, dyspareunia, PCO, PMS and breast tenderness, menstrual irregularities and infertility,...

Thyroid toxicity that affects the function of the thyroid gland not only causes thyroid dysfunction but also induce thyroid autoimmune disease.

According to Dr. Catherine Sutcliffe, the lead scientist in the study of "Endocrine Disruption of Thyroid Function" wrote, "The common factor in the direct thyroid toxicity mechanisms so far outlined is the reduction of thyroid hormone production and secretion. The reduction of thyroid hormones (T4 or T3) results in compensatory increased secretion of TSH due to the concomitant diminution of feedback control (see Figure 11.3)".

And, "It is important to note that increased TSH stimulation of the thyroid produces the same histopathological effects irrespective of the mechanism by which TSH is increased including thyroid growth evidenced by increased size and weight".

There are a number of causes of thyroid toxicity including short and long term intake of some medications (sunitinib has been found to cause thrombocytopenia and hypoglycemia in 62 patients) and xenobiotics.

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding the thyroidal toxicity.of sulforaphane, a redox-active natural product present in cruciferous vegetables like broccoli. Broccoli sprout, researchers examined the effect of the phytochemical sulforaphane effect on Nrf2 (NFE2-related factor 2) that leads to thyroid dysfunction or thyroid autoimmune disease.

According to the results of the biochemical measures of thyroid function and thyroid autoimmunity in 45 female participants in a randomized clinical trial at baseline and after 84 days of beverage administration, researchers found that
* Broccoli sprout-derived products shows promising activity for the prevention of oxidative stress-related diseases.

* Sulforaphane did not affect the serum levels of thyroid-stimulating hormone, free thyroxine, and thyroglobulin.

* More importantly, sulforaphane does not affect thyroid autoimmunity status.

Based on the findings, researchers said, "These results provide evidence in favor of the safety of chemoprevention strategies that target the activation of Nrf2 to protect against environmental exposures and other oxidative stress-related pathologies".


Taken altogether, Broccoli sprouts may is safe for the prevention and treatment of oxidative stress-related diseases without causing thyroidal toxicity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial by Chartoumpekis DV1, Ziros PG2, Chen JG3, Groopman JD4, Kensler TW1, Sykiotis GP. (PubMed)
(2) Thyroid Toxicity (Science Direct)