Thursday, 10 October 2019

Red Chinese Cabbage Inhibits Vascular Inflammatory Diseases in Vivo

By Kyle J. Norton

Inflammation is a natural immune response that protects our body against the invasion of stimuli and foreign pathogens.

During the acute phase of infection, the immune first line of defense activates the protein associated with the production of blood palettes to cover the wound and inflammatory cytokines to the site of injury with an aim to prevent and kill off harmful microorganisms.

However, overproduction of inflammatory cytokines not only can induce fever, swelling, and pain to the affected area but also damage to the nearby cells and tissue, leading to the formation of scars.

Chronic inflammatory diseases are the class of conditions involved in low-grade inflammation that affects tissue or organ. Some researchers suggested that the immune system has evolved over thousands of years to kill off the foreign invasive pathogens within a period of time, normally between 3 to 8 weeks. If the immune fails to do so, it will adapt to the new change, leading to chronic inflammation.

There are several factors that cause the onset of the conditions. Some scientists indicated untreated acute inflammation, such as an infection or injury and an autoimmune disorder involved immune system mistakenly attacking healthy tissue are the most causes of chronic inflammatory diseases.

Certain risk factors such as long-term exposure to irritants, such as industrial chemicals or polluted air, the increase in age, being obesity or obesity, low sex hormone production, sleep disorder and diet.

Furthermore, vascular inflammation increased the risk of CVD are found to have a close link between inflammation and redox balance or oxidative stress caused the imbalanced ratio of free radicals and antioxidants produced by the host.

Dr. Steven S, the lead scientist said, "Clinical trials have identified chronic inflammatory disorders as cardiovascular risks, and recent research has revealed a contribution by various inflammatory cells to vascular oxidative stress. Atherosclerosis and cardiovascular disease are closely associated with inflammation, probably due to the close interaction of inflammation with oxidative stress".

And, "The value of immunomodulation for the treatment of cardiovascular disease was recently supported by large-scale clinical trials demonstrating reduced cardiovascular mortality in patients with the established atherosclerotic disease when treated by highly specific anti-inflammatory therapies (e.g., using monoclonal antibodies against cytokines)".

Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention against disease associated with vascular inflammation, researchers examined the anti-inflammatory activities of an anthocyanin-rich extract from red Chinese cabbage (ArCC).

According to the analysis of cultured endothelial cells, ArCC treatment suppressed monocyte adhesion to tumor necrosis factor-α-in atherosclerotic plaque formation by inhibiting endothelial adhesion molecules.

The action of ArCC against vascular inflammation was attributed by decreasing the expression of a protein associated with cytokine production.

In hyperlipidemic apolipoprotein E-deficient mice, administration of ArCC (150 or 300 mg/kg/day) showed a similar effect on the inhibition of aortic inflammatory cytokines, reduction of plaque formation accompanied by the lowering the leukocyte infiltration.

Based on the results, researchers wrote, "The results suggest that the consumption of anthocyanin-rich red Chinese cabbage is closely correlated with lowering the risk of vascular inflammatory diseases".

Taken altogether, red Chinese cabbage processed abundantly anthocyanin may be considered a dietary vegetable for the prevention and treatment of vascular inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of anthocyanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anthocyanin-Rich Extract from Red Chinese Cabbage Alleviates Vascular Inflammation in Endothelial Cells and Apo E-/- Mice by Joo HK1, Choi S2, Lee YR3, Lee EO4, Park MS5, Park KB6, Kim CS7, Lim YP8, Park JT9, Jeon BH. (PubMed)
(2) Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease by Steven S1,2, Frenis K1, Oelze M1, Kalinovic S1, Kuntic M1, Bayo Jimenez MT1, Vujacic-Mirski K1, Helmstädter J1, Kröller-Schön S1, Münzel T1,3, Daiber A. (PubMed)

Turmeric Protects the Neuron Against beta-Amyloid (betaA) Insults

By Kyle J. Norton

A neuron or nerve cell is a brain cell that carries electrical impulses. Neurons formed basic cords of the nervous system inclduing the brain, spinal cord, and peripheral nerves.

The function of neurons is to process and transmit information that controls the body function.

Amyloid beta is the main component of the amyloid plaques found in the brains of Alzheimer patients.

Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.

In other words, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.

Dementia is a group of neurodegenerative diseases caused by a decline in mental ability in the older population that is severe enough to interfere with daily life, such as memory loss.

Compared to dementia, neurological disorders are a class of brain disease associated with reduced function of the brain, depending on the region of the neurons that were affected.

Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.

The disease is most prevalent in the elderly and causes over 60% of all cases of dementia.

According to the statistics, approximately 5.7 million Americans of all ages are living with Alzheimer's.

Believe it or not, 15.9 million family caregivers provided an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.

Epidemiological studies suggested that Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time. However, less 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.

Dr. Lynn M. Bekris, the lead scientist said, "Alzheimer's disease (AD) is the most common causes of neurodegenerative disorder in elderly individuals. Clinically, patients initially present with short-term memory loss, subsequently followed by executive dysfunction, confusion, agitation, and behavioral disturbances".

And, " Three causative genes have been associated with autosomal dominant familial AD (APP, PSEN1, and PSEN2) and 1 genetic risk factor (APOEε4 allele)".

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the prevention of neuronal cell death in Alzheimer's disease, researchers comapred the effects of curcuminoids, curcumin, demethoxycurcumin, and bisdemethoxycurcumin and alpha-Tocopherol on beta-Amyloid (betaA) induced oxidative stress in brain cells.

According to the results from the tested analysis, all phytochemicals isolated from turmeric blocked the insults from the from betaA(1-42) in PC12 rat pheochromocytoma and normal human umbilical vein endothelial (HUVEC) cells.

Futhermore, the ED(50) values of curcumin, demethoxycurcumin, and bisdemethoxycurcumin toward PC12 and HUVEC cells were 7.1+/-0.3, 4.7+/-0.1, 3.5+/-0.2 microg/ml and 6.8+/-0.4, 4.2+/-0.3, and 3.0+/-0.3 microg/ml, respectively.

Moreover over, according to the DPPH radical trapping experiment assay, all 4 compounds exerted a strong antioxidant activity comapred to that of alpha-tocopherol.

Additionally, the injection of alpha-Tocopherol did not protect the cells from betaA(1-42) insult even at>50 microg/ml concentration.

Based on the results, researchers wrote, " The results suggest that these compounds may be protecting the cells from betaA(1-42) insult through antioxidant pathway".


Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of MS, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult by Kim DS1, Park SY, Kim JK. (PubMed)
(2) Genetics of Alzheimer Disease by Lynn M. Bekris, PhD,1 Chang-En Yu, PhD,1 Thomas D. Bird, MD,2 and Debby W. Tsuang, MD, MSc. (PMC)

Wednesday, 9 October 2019

Turmeric Enhances the Immune Function Against the Onset of Acquired Immunodeficiency Syndrome (AIDS)

By Kyle J. Norton

Acquired immunodeficiency syndrome (AIDS) is a disease associated with human immunodeficiency virus (HIV) infection at the most advanced stage.

In other words, if an HIV infected person has a CD4, the glycoprotein found on the surface of immune cells count less than 200 cells/mm3, he/she is considered to have developed AIDS.

AIDS is caused by the infection of HIV. However, most HIV infected patients are HIV carriers.

Most common risk factors associated with HIV injection are contacted body fluids such as infected blood, milk coming from a mother who carries the HIV, vaginal or anal sex, sharing drugs needles and oral sex. 

Believe it or not, HIV cannot live outside the human body for long because the virus needs body fluid to survive.

According to the statistics, approximately, 1.1 million people in the US are living with HIV, including 15% of those don't know they are infected. Only half of the patients half are virally suppressed.
In 2016, 39,782 cases of new HIV were diagnosed.

Some researchers sexual behavior of a person may have a strong impact in increasing the risk of HIV injection. More precisely, 

Dr. Molly S. Rosenberg, the lead scientist wrote, "HIV prevalence was very high among HAALSI participants (23%, 95% confidence interval [CI]: 21 to 24), with no sex differences. Recent sexual activity was common (56%, 95% CI: 55 to 58) across all HIV status categories. Condom use was low among HIV-negative adults (15%, 95% CI: 14 to 17), higher among HIV-positive adults who were unaware of their HIV status (27%, 95% CI: 22 to 33), and dramatically higher among HIV-positive adults who were aware of their status (75%, 95% CI: 70 to 80). Casual sex and multiple partnerships were reported at moderate levels, with slightly higher estimates among HIV-positive compared to HIV-negative adults".

And, "Older HIV-positive adults in an HIV hyperendemic community of rural South Africa report sexual behaviors consistent with high HIV transmission risk. Older HIV-negative adults report sexual behaviors consistent with high HIV acquisition risk".

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a natural compound for the treatment of acquired immunodeficiency syndrome, researchers examined the immunomodulatory effects of Curcuma longa L., purple sweet potato, and mixtures of the two (CPM) in an animal model.

The study included selected C57BL/6 mice infected with LP-BM5 murine leukemia virus (MuLV), randomly divided into seven groups as follows:
* Normal control,

* Infected control (LP-BM5 MuLV infection),

* Positive control (LP-BM5 MuLV infection+dietary supplement of red ginseng 300 mg/kg body weight),

* The original powder of C. longa L. (C; LP-BM5 MuLV infection+dietary supplement of C 189 mg/kg body weight),

* The original powder of purple sweet potato (P; LP-BM5 MuLV infection+dietary supplement of P 1811 mg/kg body weight), CPM Low (CPL; LP-BM5 MuLV infection+CPM 2 g/kg body weight), and

* CPM High (CPH; LP-BM5 MuLV infection+CPM 5 g/kg body weight). Dietary supplementation lasted for 12 weeks.

According to the tested assays, dietary supplementation of CPM inhibited LP-BM5 MuLV-induced lymphadenopathy, an inflammatory disease of the lymph nodes and splenomegaly, a condition of abnormal enlargement of the spleen.

Furthermore, CPM also enhanced the immune function in recognizing the invasive and foreign virus, that may weaken the immune system to initiate the onset of infection.

In other words, CPM enhanced the immune function against the progression of MuLV.

More precisely, CPM reduced the decrease in T- and B cell proliferation, reduced the population of CD4(+)/CD8(+) T cells, and inhibited the unbalanced production of T helper-1 (Th1)/T helper-2 (Th2) cytokines in LP-BM5 MuLV-infected mice.

Moreover, the immune function also was exhibited by the injection of CPM observed by the supplement immune modulatory activity, including the inhibition of the reduction of phagocytosis in peritoneal macrophages and decreased serum levels of immunoglobulin A (IgA), immunoglobulin E (IgE), and immunoglobulin G (IgG).

Based on the results, researchers after taking other factors into account wrote, "CPM had a positive effect on immunomodulation in C57BL/6 mice induced by LP-BM5 leukemia retrovirus infection".
 

Taken altogether, turmeric used alone or combined with other herbal medicines may be considered supplements for the prevention and treatment of acquired immunodeficiency syndrome, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Effects of Curcuma longa L., Purple Sweet Potato, and Mixtures of the Two on Immunomodulation in C57BL/6J Mice Infected with LP-BM5 Murine Leukemia Retrovirus by Park SJ1, Lee D1, Lee M1, Kwon HO2, Kim H3, Park J4, Jeon W4, Cha M5, Jun S5, Park K5, Lee J. (PubMed)
(2) Immunomodulatory effects of curcumin in allergy by Kurup VP1, Barrios CS. (PubMed)
(3) Sexual Behaviors and HIV Status: A Population-Based Study Among Older Adults in Rural South Africa by Molly S. Rosenberg, MPH, PhD,*† Francesc X. Gómez-Olivé, MSc, MD, PhD,†‡§ Julia K. Rohr, MPH, PhD,† Brian C. Houle, MPH, PhD,‡‖ Chodziwadziwa W. Kabudula, Msc,‡§¶Ryan G. Wagner, MSc, PhD,‡§ Joshua A. Salomon, PhD,# Kathleen Kahn, MD, MPH, PhD,‡§**Lisa F. Berkman, MS, PhD,†‡#††‡‡ Stephen M. Tollman, MD, MPH, PhD,‡§** andTill Bärnighausen, MD, MSc, ScD. (PMC)

Cranberry Has No Effects on Urinary Disorders in Multiple Sclerosis (MS) Patients

By Kyle J. Norton

Infection is an inflammatory condition caused by a microbial invasion on body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

Most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.

Urinary tract infection (UTIs) mostly occurred in women is an infection that affects the bladder and urethra caused mostly by bacterial strains Escherichia coli (E. coli), commonly found in the gastrointestinal (GI) tract.

UTIs have been found to limit the function of the bladder and induce kidney infection.

Most common symptoms of urinary infection are persistent urge to urinate, urinary burning sensation, cloudy urine, and smelly urine.

In severe cases, patients may also experience symptoms of blood in the urine and bladder and pelvic pain.

Most common risk factors of urinary tract infection are gender, females are more like to have UTI comapred to males, sexual activity, use of birth control, and menopausal women.

Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system) casued by the immune system attacks the protective sheath (myelin) that covers nerve fibers.

MS causes communication problems between the brain and the rest of the body.

SHARON BEGLEY in examing the genetic preposition involved in MS wrote, " A newly discovered genetic mutation gives people who carry it a whopping 70 percent chance of developing multiple sclerosis, potentially opening the way toward new therapies for a debilitating neurological disorder whose ultimate cause has stumped researchers for decades".

The author continued, "The 70 percent chance of developing MS compares to a 0.1 percent risk in the general population, and the 100 or so previously known genetic variants increase the chance of MS to only about 0.3 percent at most, with no single gene packing much of a punch".

In other words, people having certain genes inherited from the parent are at the substantial risk of MS developing comapred to people who do not.

According to the statistics, in 2010/2011, approximately 93,500 Canadians were diagnosed with the disease or 290 cases per 100,000 population. Believe it or not, MS is the most prevalent in Canada comapred to other parts of the world.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the prevention of urinary infections, researchers examined the effect of cranberry extract (CE) in multiple sclerosis (MS) patients suffering from urinary disorders.

The prospective, double-blind study included a total of 171 adult MS outpatients with urinary disorders presenting at eight centers received either to cranberry extract ((36 mg proanthocyanidins per day) or matching placebo for 1-year.

According to the results of follow up, the were no difference between cranberry and placebo).
In other words, there was no difference in time to first symptomatic UTI distribution across 1 year, with an estimated hazard ratio of 0.99, 95% CI [0.61, 1.60] (p = 0.97).

Furthermore, the econdary endpoints and tolerance also did not differ between groups.

Based on the findings, researchers aid, "Taking cranberry extract versus placebo twice a day did not prevent UTI occurrence in MS patients with urinary disorders".

Taken altogether, cranberry can not be considered a remedy for the prevention and treatment of urinary disorders in MS patients, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry versus placebo in the prevention of urinary infections in multiple sclerosis: a multicenter, randomized, placebo-controlled, double-blind trial by Gallien P1, Amarenco G2, Benoit N3, Bonniaud V4, Donzé C5, Kerdraon J6, de Seze M7, Denys P8, Renault A9, Naudet F10, Reymann JM. (PubMed)
(2) Discovery of multiple sclerosis gene could inspire new therapies — if it’s right by By SHARON BEGLEY

Tuesday, 8 October 2019

Herbal Coltsfoot(Tussilago farfara) Protects the Lung Air Sacs (Alveoli) Against Emphysema

By Kyle J. Norton

Pulmonary diseases are a class of disease associated with the lungs, including asthma, COPD, influenza, pneumonia and tuberculosis, and lung cancer.

Any disease involved in breathing problems such as shortness of breath, such as, especially during physical activities, wheezing, and chest tightness that reduces the function of the lung are pulmonary diseases.

Emphysema is a type of COPD with a long term and progressive condition that cause shortness of breath, depending to the stage of lung function associated with the damage of tissues of the air sacs (alveoli) in the lungs.

In other words, if the early onset of emphysema is inhibited, the risk of pulmonary diseases may be significantly decreased.

Emphysema is a type of COPD with a long term and progressive condition that causes shortness of breath, depending to the stage of lung function associated with the damage of tissues of the air sacs (alveoli) in the lungs.

Most common pulmonary diseases are
* Asthma
Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.

* Pneumothorax
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung, leading to shortness of breath.

* Bronchitis
Bronchitis is a medical condition associated with the inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma.

* Chronic bronchitis
Chronic bronchitis is a chronic inflammation of the lung’s bronchi that cause the increased production of mucus in the lung associated with the difficulty of breathing.

* Pneumonia
Pneumonia is a condition of the inflammation of the lung caused by bacteria, such as bacterial infection, Streptococcus pneumoniae or influenza viruses in most cases.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia.

The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound for the treatment of lung disease associated with shortness of breath, researchers examined the effect of cranberry combined other Chinese medicine on the measurement of the maximal expiratory flow-volume curve (MEFV) in asthmatic patients.

The study included Chinese herbal decoction of the chiefly invigorating kidney including Viscum coloratum 15g, Psoralea corylifolia 15g, Eucommia ulmoides 15g, Lycium chinense 9g, Tussilago farfara 15g, Artemisia capillaris 9g, and Pogostemon cablin 9g as a daily dosage for 10 weeks.

According to the results of the measurement of the MEFV curves changes before and after treatment, the decoction improved different parameters of MEFV to some extent.

After 10 weeks of treatment, the decoction showed a significant effect that reverse airway obstruction of asthmatics in the convalescent stage.

By inhibiting the early stage of airway obstruction of asthmatics, cranberry combined with other Chinese medicine can prevent the onset of emphysema.

Based on the findings, researchers said, "the treatment with Chinese herbs of chiefly invigorating Kidney deserved to be propagated (associated with emphysema) ".

Taken altogether, coltsfoot may be considered a remedy for the prevention of shortness of breath in lung disease patients, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs].[Article in Chinese] by Fu JX. (PubMed)

Betaxanthins Protects Against the Onset of Fatty Liver

By Kyle J. Norton

A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.

Non-alcoholic fatty liver (NAFL) is the early stage of nonalcoholic steatohepatitis (NASH) caused by the accumulation of fat in the liver, other than excessive use of alcohol.

Nonalcoholic steatohepatitis (NASH) is a type of inflammatory non-alcoholic fatty liver disease caused by excessive fat accumulated in the liver.

Nonalcoholic steatohepatitis (NASH) is asymptomatic until the condition is developed into cirrhosis, the condition that causes advanced liver scars and reduced the performance of the liver.

In other words, if more than 5% – 10% percent of your liver’s weight is fat, you have a fatty liver (steatosis).

According to the statistics, non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of liver disease affecting 100 million people in the US. Out of that number, approximately 20% of people have NASH.

Medical conditions such as obesity, metabolic syndrome, and type 2 diabetes are some of the metabolic risk factors that have been found to induce the development of NASH.

As of today, there is no effective treatment of NASH. Depending on the condition people with overweight or obese are recommended to lose weight. The aim of medical treatment is to reduce the symptoms and delay the progression of the condition and improve the quality of life.

Out of many prevalent factors that cause the onset of NASH, some researchers suggested that the promotion of high-fat diet over the past few decades induced high percentage of the overweight and obese population may be the major culprit associated with the rise of NASH.

Dr. Jensen VS, the lead scientist wrote, "Hepatic dysfunction and inflammation was confirmed in HFD-fed rats by elevated levels of hepatic MCP-1 (p < 0.0001), TNF-alpha (p < 0.001) and plasma β-hydroxybutyrate (p < 0.0001), and in NASH-fed rats by elevated levels of hepatic MCP-1 (p < 0.01), increased hepatic macrophage infiltration (p < 0.001), and higher plasma levels of alanine aminotransferase (p < 0.0001) aspartate aminotransferase (p < 0.05), haptoglobin (p < 0.001) and TIMP-1 (p < 0.01) compared to Control".

And, " dietary fat and cholesterol are the primary drivers of NAFLD development and progression in rats, while fructose mostly exerts its effect on the circulating lipid pool".

Betaxanthins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.

On finding a potent ingredient for the treatment of liver disease, researchers investigated the protecting effects of bioactive agents of the lyophilized table beet and carrot powder on fatty liver.

The study included male Wistar rats fed with chow with or without high fat (2% cholesterol, 0.5% cholic acid, 20% sunflower oil) and treated with 0.1 or 1 g/bwkg/day natural product for ten days parallel with the feedings.

Based on the tested analysis, the higher dose of the natural product decreased the expression of free radicals induced by the high-fat diet.

Pro-inflammatory cytokines induced by the high-fat diet such as cyclooxygenase-2, inducible nitric oxide synthase, and tumor necrosis factor-α mRNA-levels in the liver tissues were normalized by the natural product.

Furthermore, concentrations associated with the expression of antioxidants were higher in fatty liver, the natural product did not cause significant changes in all global antioxidant parameters.

Collectively, researchers said, "Lyophilized table beet and carrot proved to be a "functional food" in rats with alimentary fat-induced fatty liver. It cannot be ruled out that this beneficial effect may have clinical relevance".

Taken altogether, betaxanthins used alone or combined with other antioxidants for the prevention and treatment of fatty liver,  pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1)[Experimental food-induced fatty liver and its adjuvant therapy with natural bioactive substances].[Article in Hungarian] by Hegedüs V1, Gerö D, Mihály Z, Szijártó A, Zelles T, Sárdi E. (PubMed)
(2) Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats by Jensen VS1,2, Hvid H2, Damgaard J2, Nygaard H2, Ingvorsen C3, Wulff EM4, Lykkesfeldt J1, Fledelius C. (PubMed)

Monday, 7 October 2019

Herbal Turmeric Inhibits the Risk of Peripheral Arterial Disease

By Kyle J. Norton

Peripheral artery disease is a common circulatory condition caused by narrowed arteries that reduce blood flow to your limbs.

Most cases of peripheral artery disease have been associated with the accumulation of plaque in thicking and hardening the arteries, a leading cause of atherosclerosis.

Most common prevalent factors associated with peripheral artery disease are tobacco, physical inactivity, and an unhealthy diet with high in fat, processed food, and red meat and low in fruits and vegetables.

Most patients with the peripheral arterial disease are asymptomatic or experience a mild case of pain in the leg while walking. However, as the disease progression, some patients may also experience symptoms of leg numbness or weakness, coldness in your lower leg or foot, sores on your toes, feet or legs that won't heal, a change in the color of your legs, slower growth of your toenails and shiny skin on your legs.

Some men also experience the syndrome of erectile dysfunction in severe case.

Conventionally, treatment of peripheral arterial disease is focusing to improve symptoms, such as leg pain, and quality of life and stopping the progression atherosclerosis associated with the risk of heart attack and stroke, including medication to lower cholesterol, blood pressure and blood sugar.

In some cases, surgery may be necessary to treat peripheral artery disease if patients experience claudication that does not respond to medicine.

Some researchers in the investigation of the effect of the heart-healthy diet on peripheral arterial disease wrote, "Peripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature".

And, "The nutrients reviewed included omega-3 polyunsaturated fatty acids (n-3 PUFAs), folate and B-series vitamins, and anti-oxidants. The diet plans described include the DASH diet, Mediterranean diet, low-fat diet, low carbohydrate diet, Dr. Dean Ornish’s Spectrum® Diet and Dr. Andrew Weil’s Anti-Inflammatory Diet".

In other words, by changing to a healthy diet with more fruits and vegetable and less red meat, saturated and trans fat, processed foods peripheral arterial disease may be preventable.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.


The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the treatment of heart diseases, researchers examined curcumin treatment improves tissue repair and perfusion recovery in a mouse model of diabetic PAD.

Mice with PAD selected to the study with a normal glycaemic profile treated with curcumin, improved perfusion recovery, observed by the increased capillary density and elevated microRNA (miR)-93 expression in the ischemic muscle tissue.

In vitro, cultured endothelial cells under simulated ischemia, treated with curcumin improved endothelial cell viability and enhanced tube formation.

However, improved endothelial cell viability and enhanced tube formation were inhibited in the presence of the miR-93 inhibitor, regardless of the administration curcumin.

Based on the findings, researchers said, "curcumin had beneficial effects in non-diabetic PAD by improving angiogenesis, which may have been achieved partially via the promotion of miR-93 expression".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of peripheral arterial disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin improves perfusion recovery in experimental peripheral arterial diseaseby upregulating microRNA-93 expression by Zhang J1,2, Wang Q1, Rao G1, Qiu J1, He R. (PubMed)
(2) Advancing Beyond the ‘Heart-Healthy Diet’ for Peripheral Arterial Disease by Emily V. Nosova,1,2 Michael S. Conte,1,3 and S. Marlene Grenon. (PMC)