Dithiolthiones, a bioactive plant-based compound found in many vegetables may have a strong implication in reducing the risk and treatment of liver diseases, some studies suggested.
Liver protection is an action, including the use of substances to protect the liver function against damage or injury.
There are many causes of liver diseases associated with a variety of factors including; viruses, toxins, genetics, alcohol, and unknown causes.
However, one the major cause of the liver diseases are toxins accumulation. Infectious viral hepatitis can produce toxins to protect them against the expression of antioxidant enzymes produced by the host body and prevent the attack of the systematic immune response.
And, long-term excessive alcohol drinking is generally known to cause the onset of alcoholic liver disease, the very early stage of liver cancer.
Liver toxins accumulated over the years of unhealthy diet with much in saturated and trans fat, red meat and processed foods and fewer in fruits and vegetables.
These results suggested that by changing the diet pattern by increasing intake more in fruits and vegetable and whole grain and reducing intake of the saturated and trans fat, red meat and processed foods accompanied by a healthy lifestyle, risk of liver diseases are decreased substantially.
Dithiolthiones are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
The effect of drug anisyldithiolthione (ADT) was attributed to its major compound dithiolthiones, therefore application dithiolthiones directly may have the similar effect as of the drug anisyldithiolthione (ADT).
* Dithiolthiones inhibited the lipid peroxidation induced in rat liver microsomes either chemically by FeSO4 and reducing agents (cysteine or ascorbate)
* Dithiolthiones m also has a potency similar to those of propyl gallate and toxicity caused by the ethane exhalation by rats treated by CCI4 (ID50 approximately 5mg per kg).
The effect of drug anisyldithiolthione (ADT) was attributed to its major compound dithiolthiones, therefore application dithiolthiones directly may have the similar effect as of the drug anisyldithiolthione (ADT).
* Dithiolthiones inhibited the lipid peroxidation induced in rat liver microsomes either chemically by FeSO4 and reducing agents (cysteine or ascorbate)
* Dithiolthiones m also has a potency similar to those of propyl gallate and toxicity caused by the ethane exhalation by rats treated by CCI4 (ID50 approximately 5mg per kg).
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione by Mansuy D, Sassi A, Dansette PM, Plat M.(PubMed)
(2) Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice by Warnet JM1, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR.(PubMed).
(3) Relationship between Diet and Non-alcoholic Fatty Liver Disease: A Review Article by Mirmiran P1, Amirhamidi Z1, Ejtahed HS1, Bahadoran Z1, Azizi F. (PubMed)
(4) Burden of Chronic Viral Hepatitis and Liver Cirrhosis in Brazil - the Brazilian Global Burden of Disease Study by de Carvalho JR1, Villela-Nogueira CA2, Perez RM3, Portugal FB4, Flor LS5, Campos MR5, Schramm JMA. (PubMed)