Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Tuesday, 17 October 2017

Food therapy: Coffee Caffeine In Risk of Systemic Lupus Erythematosus in Women with Mutation of Gene NAT2

Kyle J. Norton

Whole food ingredients in herbal plant have been found to process some significant effects in reduced risk and treatment of various diseases, but single ingredient isolated from such plants may induce opposite responses.

Intake of coffee caffeine daily has induced conflicted results in risk of auto immune disease, systemic lupus erythematosus epidemiological studies suggested.

In the assessment of 152 SLE cases and 427 healthy controls, in Japanese women in testing the interaction of NAT2 polymorphism, acting primarily in the liver to detoxify a large number of chemicals including caffeine and consumption of beverages, researchers found that coffee with a relative risk of 1.57 showed a significant increased risk of SLE,

Mutation of gene NAT2, involved in the metabolism of several compounds relevant in pharmacology or toxicology showed a direct effect in significantly modified alcohol use and black tea consumption on SLE, but not in coffee.

These findings suggested that certain beverages may have an implication in elevated gene change in risk of systemic lupus erythematosus, such as alcohol in reduced but black tea in increased risk of systemic lupus erythematosus.

Other, in the evaluated possibility of environmental lupus erythematosus provocative substances eliminated by acetylation in 36 Chinese women with mild, stable, and confirmed lupus erythematosus and 36 healthy control subjects matched for age, sex, and ethnic origin, researchers at the University of Hong Kong. found that 1 - 4 hours after drinking a strong cup of coffee (caffeine), there was no association between slow acetylator status and lupus erythematosus in the both study subjects.

Acetylator is found to associated to a relatively high incidence of systemic lupus erythematosus.

Taking altogether, there is no doubt that coffee caffeine only has a direct effect in increased risk of systemic lupus erythematosus in women with mutation gene NAT, but not other environmental provocative substances. Further cohost and large sample size are necessary to reassess these implications.

Author Biography

Sources
(1) Modifying effect of N-acetyltransferase 2 genotype on the association between systemic lupus erythematosus and consumption of alcohol and caffeine-rich beverages by Kiyohara C1, Washio M, Horiuchi T, Asami T, Ide S, Atsumi T, Kobashi G, Takahashi H, Tada Y; Kyushu Sapporo SLE (KYSS) Study Group(PubMed)
(2) Coffee and autoimmunity: More than a mere hot beverage!by Sharif K1, Watad A1, Bragazzi NL2, Adawi M3, Amital H1, Shoenfeld Y4.(PubMed)
(3) Lack of association between slow acetylator status and spontaneous lupus erythematosus by Kumana CR1, Chan MM, Wong KL, Wong RW, Kou M, Lauder IJ.(PubMed)

Food Therapy: Beet, The Best Anti Liver Cancer Natural functional Food

Kyle J. Norton

Beet root, one of popular functional vegetable may hold a key in reduced risk and treatment of liver cancer, a respectable study opinionated.

Liver cancer is a medical condition characterized by irregular cell growth and multiplied uncontrollably in liver tissues.

Beet, best known as the beetroot or garden beet, belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the Howard University, in liver tumor induced by injection of tumor initiation with N-nitrosodiethylamine (DEN, 30 mg/kg) in mice model, mice group treated with oral administration of 0.0025% betanin isolated from beet or beet root, exerted a very significant effect on both the incidence and multiplicity of the liver tumors.

Dr. Kapadia GJ, the lead author suggested, betanin, the major chemical compound found in beet root is an effective cancer chemopreventive agent in mice.

Regular consumption of the vegetable may ameliorate against the incidence of cancers, including liver cancer.

In the findings of natural food in compared to conventional anticancer drugs in high resistance HepG2 liver cancer cells, researchers at the University of Urbino "Carlo Bo" found that natural compound Vitexin-2-O-xyloside (XVX) and avenanthramides (AVNs) isolated from beet, exhibited antiproliferative and pro-apoptotic effects by sulforhodamine B method, and caspase activity assays, respectively.

The study also showed the inhibition of the liver cell line may be a result of the phytochemicals activities in activation of proteins in regulated progression of apoptosis and prevented gene in over expression of pro cancer cell survival.

More importantly, the efficacy of beetroot in reduced incidence of early onset of liver cancer may also attribute to the antioxidant property in prevention of over production of free radical which was known as an independent risk factor in inducing liver cancer, measured by Cellular antioxidant activity (CAA) assay.

Other in the examine of the effect of betaxanthins and betacyanins efficacy in treatment of various cancers, postulated that the isolated phytochemicals may be a potential natural agents in inhibited cancer cell lines intrinsically and extrinsically in induced apoptosis.

More importantly, using Vitexin-2- O-xyloside, betaxanthins and betacyanins combination with conventional anticancer drugs may be a future treatment in reduce conventional anticancer drugs toxicity and overcome the expression of multidrug resistance of cancer cells.

Collectively, these findings may suggested that intake of functional food - beet root regularly may reduce risk and treatment of liver cancer, but further study may be necessary for validity.

Author Biography

Sources
(1) Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot by Kapadia GJ1, Azuine MA, Sridhar R, Okuda Y, Tsuruta A, Ichiishi E, Mukainake T, Takasaki M, Konoshima T, Nishino H, Tokuda H.(PubMed)
(2) Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms by Scarpa ES1, Antonini E1, Palma F1, Mari M1, Ninfali P2.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)

Monday, 16 October 2017

Food Therapy: Beet, a functional Food in Reduced Risk and Treatment of Parkinson's disease(PD)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Beet or beet root may be considered as functional food for reduced risk of early onset and treatment of Parkinson's disease(PD), a recent study suggested.

Parkinson's disease (PD) is a condition of neurodegenrative disease progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw and face. bradykinesia ......

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.

Concentrations of 200, and 300 mg/kg extract exhibited the most effects in compared dose of 100mg/kg.

Furthermore, at the higher doses, treatment animals also exerted an improvement of locomotor functioning and grip strength analyzed by MEBV.

The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibited the production of lipid peroxidation (LPO), an important process in causing cell dysfunction in PD patients.

Not only that, injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in rat brain.

Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".

Other researchers also suggested that intake of beet juice may improve blood circulation of the brain's white matter of the frontal lobes associated to the development of dementia and other cognitive conditions, including risk of PD and PD progression in older adult.

Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that good diet consisting of a lot of fruits and vegetables can contribute to overall good health".

Collectively, the finding evidences suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect in reduced prevalence of early onset and progression of Parkinson's disease (PD) and may be considered as a functional food. for these purposes.

Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Eppin(Medical news today)

Alternative Therapy: Yoga, in The Early Onset and Treatment of Hyperlipidemia

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

People who participated in yoga class are at a reduced risk of developed hyperglycemia, a renowned study suggested.

Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

Hyperlipidemia is a condition of abnormal high cholesterol in the blood stream and considered as a early signed of heart disease developing.

Short term yoga lessons showed a strong impact on some of the biochemical indicators, such as high blood cholesterol and glucose in increased risk for cardiovascular disease and diabetes mellitus.

In a study based on the colection of data of 98 subjects (67 male, 31 female), ages 20-74 years, who attended one of our programs with hypertension, coronary artery disease, diabetes mellitus, and a variety of other illnesses, yoga participants showed a significant in lower serum total cholesterol, low-density lipoprotein (LDL) cholesterol, very- LDL cholesterol and and total triglycerides with improvement of he ratio of total cholesterol to high density lipoprotein (HDL) cholesterol, on the last day of the course compared to the first day of the course.

According to the All India Institute of Medical Sciences, yoga attendees experienced also a decreased fasting plasma glucose and serum lipoprotein profile through analysis of blood profile.

Additionally, a study of an outpatient facility at All India Institute of Medical Sciences, New Delhi, a tertiary health care centre, also showed an improvement of blood cholesterol through increased levels of high-density lipoprotein cholesterol in a duration of 10 days of yoga class..

Dr. Yadav RK, the lead author said, (in) 38 participants (147 women, 91 men, 38.81±11.40 years) included in the study said, "There was a significant increase in HDL-c levels from baseline to day 10 (42.93±5.00 vs 43.52±5.07 mg/dL, P = 0.043). Notably, HDL-c was significantly improved in those for whom the baseline HDL-c levels were lower than the recommended values".

In support of the above differentiation, study of yoga effect on glucose metabolism and blood lipid levels of 90 adolescents aged between 15 and 18 years who met the Rotterdam criteria for PCOS conducted the Swami Vivekananda Yoga Anusandhana Samsthana (SVYSA) University showed a improving glucose, lipid, and insulin values, including insulin resistance values, in adolescent girls with PCOS independent of anthropometric changes in compared conventional physical exercises group.

Collectively, There is no doubt that yoga may be used a therapeutic treatment in reduced risk of hyperlipidemia and reduced risk of early on set of cardiovascular disease and diabetes induced by abnormal high blood cholesterol.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources

(1) A brief but comprehensive lifestyle education program based on yoga reduces risk factors for cardiovascular disease and diabetes mellitus by Bijlani RL1, Vempati RP, Yadav RK, Ray RB, Gupta V, Sharma R, Mehta N, Mahapatra SC.(PubMed)
(2) High-density lipoprotein cholesterol increases following a short-term yoga-based lifestyleintervention: a non-pharmacological modulation by Yadav RK, Magan D, Yadav R, Sarvottam K, Netam R.(PubMed)
(3) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome by Nidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)

Food Therapy: Black Bean, A Potent Whole Food For Ameliorated Risk and Treatment of Colon Cancer

By Kyle J. Norton

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient. In compared to herbal medicine; food therapy even takes longer than six months to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Intake of black bean and other common bean may associate to ameliorated risk of colon cancer, a joint study of renowned institute study suggested.

Black bean, a small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

Colon cancer is a condition characterized by cell growth disorderly and uncontrollably in the colon.

In the study of 95 male F344 rats fed control (AIN) diets upon arrival at 4 and 5 weeks, then injected with AOM (15 mg/kg) or saline and one week later administered an AIN, BB-, or SF-based diet, at week 41 mice fed with BB- and SF-fed rats showed a higher inhibition of colon cancer cells through certain genes expression involved energy metabolism, modulated cellular apoptosis and immunity.

Dr. Rondini EA, the lead author said, " beans inhibit coloncarcinogenesis by modulating cellular kinetics and reducing inflammation, potentially by preserving mucosal barrier function."

Other in the study with rats fed a modified AIN-93G diet (control) or diets containing 75% black beans or 75% navy beans for 4 wk, and then colon cancer initiated by administration of two injections of azoxymethane 1 wk apart, after 2nd injection, rats fed the black bean (9%) showed a significantly increased 9% risk of colon cancer cell, im compared to 14% in navy bean diets than 36% in rats fed the control diet.

Further more, rats fed the black bean also showed a lower rate of total tumor multiplicity in compared to other 2 groups.

More importantly, black bean fed group not only reduced the risk factors in colon cancer developed by 44-75%, but also improved significantly less body fat and concentrations of butyrate in the distal colon in suppression of colonic inflammation induced ulcerative colitis (UC) and colorectal cancer.

In the findings of new phytochemicals in the black bean with action against various types of cancer, Dr. Dong M, the lead researcher at the Cornell University showeded that 14 out of 19 newly acquired flavonoids, showed potent antioxidant and antiproliferative activities against Caco-2 cell growth, the human colon cancer cell line.

Taking together, black bean may have therapeutic potential to become a pharmaceutical product in reduced risk and treatment of colon cancer. But further human trials are necessary for more validities.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats by.Rondini EA1, Bennink MR.(PubMed)
(2) Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats by Hangen L1, Bennink MR.(PubMed)
(3) Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activities by Dong M1, He X, Liu RH.(PubMed)

Sunday, 15 October 2017

Alternative Therapy: Yoga reduced Risk of Early Onset and Progression of Dementia

Yoga may have a direct benefit in reduced risk of depressive symptoms and progression of dementia, a recent renowned joint study suggested.

Dementia is the loss of mental ability severed enough to interfere with people's every life. Alzheimer's disease is the most common type of dementia in aging people. About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age.

Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the joint study led by the Stanford University, yoga may be one the physical exercise and alternative interventions to treat and reduce risk of cognitive decline and suppress.depression as modifiable risk factor in inducing cognitive decline and dementia.

Dr. Mathersul DC, the lead author said, "Notably, exercise and yoga are two interventions known to both reduce symptoms of depression and improve cognitive function".

In a total of 68 residents in long-term care facilities in southern Taiwan, aged 60 years and above with mild to moderate dementia selected with experimental group of 33 elders participated in a 12-weeks yoga training program of three 55-minute sessions a week; and a control group of 35 elders maintained their usual daily activities, yoga treatment group expressed a better mental and physical health including lowered blood pressure, reduced respiration rate, strengthened cardiopulmonary fitness, enhanced body flexibility, improved muscle strength and endurance, improved balance, and increased joints motion in compared control.

The yoga participated group also showed a significant improvement of the depression state and problem behaviors due to cognitive decline.

Additionally, in the searching of a total of 700 articles published from 1963 to 14th December 2016, 94 articles indicated that yoga might be considered as an effective adjuvant for the patients with various neurological disorders, including dementia.

Collectively, Yoga attended elder may have beneficiary in reduced risk of early onset and progression of neuro decline, accompaned with change of style and diet.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) The Roles of Exercise and Yoga in Ameliorating Depression as a Risk Factor for Cognitive Decline by Mathersul DC1, Rosenbaum S2.(PubMed)
(2) Using silver yoga exercises to promote physical and mental health of elders with dementia in long-term care facilities by Fan JT1, Chen KM.(PubMed)
(3) Evidence based effects of yoga in neurological disorders by Mooventhan A1, Nivethitha L2.(PubMed)

Herbal Therapy: Green Tea, The #1 Functional Food for Prevention and Treatment of Metabolic Syndrome

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The use of plants for healing purposes hasbeen predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

A recent study conducted by renowned institute suggested that regular drinking of green tea may reduce risk of prevalence of metabolic syndrome.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Metabolic syndrome is a biochemical and physiological factors associated with risk of cardiovascular disease and type 2 diabetes.

In a cross-sectional population-based survey including 8,821 adults (51.4% female) conducted in Krakow, Poland., both coffee and tea drinker showed a negatively associated with MetS (OR 0.75, 95% CI 0.66, 0.86 and OR 0.79, 95% CI 0.67, 0.92, respectively).

The study also found that high tea consumers had lower BMI, waist circumference, but moderated decreased diastolic blood pressure, as well as negatively correlated central obesity and fasting plasma glucose in women, but not in men, in compared low drinker,

Other, in the study of dietary polyphenols, a major compound found in green tea including 8821 adults (51.4 % female), using food frequency questionnaires and matching food consumption data with the Phenol-Explorer database.conducted in Kraków, Poland, dietary polyphenol intake in the highest quartile was associated inversely to the development of MetS (OR 0.80; 95 % CI 0.64, 0.98 and OR 0.70; 95 % CI 0.56, 0.86 for both men and women, respectively).
g
Dietary polyphenols in high quality showed a negative association of WC, blood pressure, high lipoprotein cholesterol, and triglycerides in women, and fasting plasma glucose in both gender..

Dr. Grosso G, the lead author said, "(Depending to types of polyphenols) phenolic acids and stilbenes were significantly associated with MetS; lignans and stilbenes with WC; phenolic acids with blood pressure and triglycerides; and flavonoids with fasting plasma glucose" and " Among specific subclasses of polyphenols, hydroxycinnamic acids, flavanols, and dihydrochalcones had the most relevant role."

In support the role of used of polyphenol for treatment of Metabolic syndrome, in a total of 2725 participants free of hypertension at baseline tested for blood pressure or taking hypertensive medication within the last 2 weeks at 2-4-year follow-up visit was conducted by the Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, researchers showed that diet of highest quartile of total polyphenol intake was associated with 31% decreased risk of hypertension compared with the lowest intake (OR 0.69, 95% CI 0.48, 0.98) in women with no significant association in men.

The study also stated that most influential phytochemicals in reduced risk and treatment of metabolic syndrome ingredients are phenolic acids, hydroxycynnamic acids as they showed a independently associated to lower odds of hypertension (OR 0.66, 95% CI 0.47, 0.93) in comparison to others.

Taking together, green tea with major chemical compounds of polyphenol may be used as functional foods in prevention and treatment of metabolic syndrome.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3.(PubMed)
(2) Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Stefler D4, Bobak M4, Pająk A3.(PubMed)
(3) Dietary polyphenol intake and risk of hypertension in the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Kozela M3, Stefler D4, Bobak M4, Pajak A3.(PubMed)