Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Friday, 1 September 2017

Herbal Therapy: Aloe Vera, The Immunomodulatory Whole Food Medicine

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan, used in herbal medicine in treating various diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc.

Immunomodulatory effect is an action involved regulation of immune system against invasion of foreign subjects in promoted infection and inflammation.

According to the joint study lead by the Sahlgrenska Academy at University of Gothenburg, oral administrated (AVH200®), an aloe vera extract modified the protein involved activation, proliferation and cytokine secretion of healthy human blood T cells, in a dose dependent manner.

Aloe-emodin(AE), a major constituent found in Aloe Vera exerted a positive effect in significantly enhanced dabrafenib (a BARF inhibitor) antiproliferative activity of mutant cell lines through immunomodulatory activity

The study also confirmed that AE possesses remarkable antineoplastic properties of drug(dabrafenib) used in treatment of metastatic colon cancer, against melanoma cells.

In candida albicans, A. vera extract and its fractions on infected macrophages demonstrated an anti fungal effect through activated and modulated the immune response.

Furthermore, the extract also significantly increased cell viability of macrophages, in comparison with control group.

Additionally, polysaccharide isolated from Aloe Vera explictly also enhanced immune function in producing specific antibody and inducing delayed hypersensitivity in mice model.

Collectively, chemical constituents found in Aloe vera have showed to exhibit immunomodulatory effects in regulated immune function against foreign invasion and allergic reactions and irregular cell growth, but further studies are necessary to confirm this validation.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effects of Aloe barbadensis Mill. extract (AVH200®) on human blood T cell activity in vitro by Ahluwalia B1, Magnusson MK2, Isaksson S3, Larsson F4, Öhman L5.(PubMed)
(2) Aloe-emodin exerts a potent anticancer and immunomodulatory activity on BRAF-mutated human melanoma cells by Tabolacci C1, Cordella M2, Turcano L3, Rossi S2, Lentini A3, Mariotti S4, Nisini R4, Sette G5, Eramo A2, Piredda L3, De Maria R5, Facchiano F6, Beninati S3.(PubMed)
(3) Immunomodulatory effects of Aloe vera and its fractions on response of macrophages against Candida albicans by Farahnejad Z1, Ghazanfari T, Yaraee R(PubMed)
(4) An anti-complementary polysaccharide with immunological adjuvant activity from the leaf parenchyma gel of Aloe vera by t'Hart LA, van den Berg AJ, Kuis L, van Dijk H, Labadie RP.(PubMed)

Food Therapy: Cruciferous Vegetables, the Best Anti- Obesity Natural Whole Food Medicine

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Obesity is a medical condition of excess body fat has accumulated overtime.

According to the Body Mass Index(BMI), a BMI over 30 is an indication of obesity. Approximately, 68% of American population are either overweight or obese.

According to the Taipei Medical University indole-3-carbinol (I3C), isolated from Cruciferous Vegetables, induced anti obesity expression by inhibited intracellular lipid accumulation of cell size increase of fat cells and pro inflammatory cytokine interleukin-6 (IL-6), the parameters related to obesity.

In Male C57BL/6 mice fed with a control diet (C group), high-fat diet (HF group) and HF+5 mg kg(-1) I3C (HFI group).than HFI group injected with I3C intraperitoneally for 12 weeks, I3C treatment group ameliorated free radicals production and increase expression of gene in regulated fatty acid storage and glucose metabolism, important parameters in related to obese onset.

Additionally, in vivo treatment with I3C reduced inflammation caused by the infiltration of macrophages, a type of white blood cell in epididymal adipose tissue and in vitro, addition of I3C decreased oxidative production and activation of inflammatory expression.

Dr. Chang HP, the lead author said, " decreased body weight and fat accumulation,....., were associated with improved glucose tolerance and with modulated expression of adipokines(secreted by adipose tissue.) and lipogenic(the process converted to fatty acids)-associated gene products"

In fact, Indole-3-carbinol (I3C) prevents diet-induced obesity by modulation of multiple genes expression involved the process of cell differentiation in production of fat cell and induced heat cause by inflammatory of fat cell underneath the skin.

By inhibiting the gene expression involved obesity and regulating the cell differentiation in fat cell and preventing fat tissues accumulation through its chemical constituents, cruciferous vegetable may have a potential benefit in preventing obesity and metabolic disorders.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes by Chang HP1, Wang ML, Hsu CY, Liu ME, Chan MH, Chen YH.(PubMed)
(2) Antiobesity activities of indole-3-carbinol in high-fat-diet-induced obese mice by Chang HP1, Wang ML, Chan MH, Chiu YS, Chen YH.(PubMed)
(3) Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice by Choi Y1, Kim Y, Park S, Lee KW, Park T.(PubMed)

10 Incredible Health Benefits of Herbal Alfalfa

Kyle J. Norton

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding and used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc.

Chemical constituents
Flavones, isoflavones, sterols, Bichanin, Coumestrol, Diadzein, Formonetin, Genistein, coumarin derivatives,.......

1. Herbal Alfalfa and diabetes
2. Herbal Alfalfa and cholesterol
3. Herbal Alfalfa as an Antioxidant
4. Herbal Alfalfa and Estrogenic effects
5. Herbal Alfalfa and Menopausal Symptoms
6. Herbal Alfalfa and Cancers
7. Herbal Therapy: Alfalfa, the Immunomodulatory Natural Whole Food Medicine
8. Herbal Therapy: Alfalfa, the Natural Anti microbial Whole Food Medicine
9. Herbal Therapy: Alfalfa, the Anti-inflammatory Natural Whole Food
10. Herbal Therapy: Alfalfa, the Neuroprotective Natural Whole Food

Side effects
1. High amount of vitamin K may reduce the effectiveness of anticogulation medicine
2. Alfalfa may cause additive effects for women who are under estrogen replacement therapy or taking the oral contraceptive pill.
3. It may cause stomach upset and diarrhea
4. The herb may induce lupus erythematosu due to its chemical constituent L-canavanine.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Thursday, 31 August 2017

Alternative Therapy: Yoga Reduced Psychological Symptoms and Adverse Effects of Treatment in Post Cancer Patients

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cancer is a class of diseases in which a group of cells has growth and multiplied disorderly and uncontrollably in our body. Depending to the grade, aggressive cancer cells might spread to distant tissues and organs in the late stage.

Yoga may be used as integrated form of excise for post-cancer patients in reduced side effects of conventional treatment and improved psychological aspects.

People who participated in yoga class are likely to experience less or lower levels of anxiety, a renowned study suggested.

Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the review of literature conducted by the Memorial Hermann Greater Heights Hospital, showed a importantly support for the use of yoga as an evidence-based nursing intervention.

Dr. Sisk A, the lead author said, " Yoga techniques can be easily integrated into nursing practice and have been shown to be beneficial for patients and nurses".

As an integrated therapy, yoga participants showed a significant awareness of breath, relaxation, exercise, and social support in improved quality of life in patients with cancer.

Yoga practice also is found to assist cancer survivors in managing psychological symptoms such as depression, anxiety, insomnia, pain, and fatigue.

In the study of 38 eligible breast cancer survivors (per-screened with PAR-Q/PAR-MED-X) randomly assigned to either the intervention (n=20) or control group (n=18) with all participants completed pre- and post-testing assessments immediately before and after the yoga program, respectively, yoga program participants showed a remarkable improvement of psychosocial variables of emotional irritability, gastrointestinal symptoms, cognitive disorganization, mood disturbance, tension, depression, and confusion (all p's <0.10) in compared control group.

The study also indicated a significant improvements of post-intervention on a number of physical fitness variables.in both groups.

Collectively, yoga has significant potential in reduced psychological symptoms and side effects of conventional treatment, promoted physical fitness and quality of life in post cancer patients and may be used as integrated form of therapy addition to convention intervention.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Evidence-Based Yoga Interventions for Patients With Cancer by Sisk A1, Fonteyn M.(PubMed)
(2) Integrating yoga into cancer care by DiStasio SA1(PubMed)

7 Unbelievable Health Benefits of Garbanzo beans (chickpeas, Cicer)

Kyle J. Norton

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, with high in protein and minerals, cultivated as vegetables, native to Middle East.

Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Vitamin E
14. Vitamin K
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc
20. Etc.

7 Unbelievable Health Benefits of Garbanzo beans (chickpeas, Cicer)

1. Food Therapy: Garbanzo beans as antioxidant for free radical scavenging & inhibited cancer cell cycle progression
2. Food Therapy: Garbanzo beans(Chickpea) The Best antioxidant for anti fungal effects in Whole food medicine
3. Food Therapy: Garbanzo beans(Chickpea) in increased function of Bowel health
4. Food Therapy: Garbanzo bean(Chickpea) The Best free radical scavenger in Whole food medicine
5. Food Therapy: Garbanzo bean(Chickpea), The Best whole food medicine for reduced risk and symptoms of CVD
6. Food Therapy: Garbanzo beans( chickpea) reduce symptoms and complications of patients with diabetes
7. Food Therapy: Garbanzo bean( chickpea) reduces risk of dyslipidemia

Side effects
1. Purines
Garbanzo bean contains measure amount of purines, excessive intake of purines can cause gout and formation of kidney stones.
2. Sulphites
Sulphites in garbanzo bean can cause symptoms of rapid heartbeat, headache and disorientation for certain people.
3. Etc.
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Food Therapy: Asparagus, the Anti Inflammatory Natural Whole Food

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Asparagus may be next potential whole food medicine in inhibited expression of pro inflammatory cytokins in inducing fever, pain and swollen in affect location,....

Inflammation is a natural expression by immune system in induction of while blood cells for protection our body against infection with foreign invasion.

According to the Korea Institute of Oriental Medicine, in an investigation of chronic skin inflammation, using 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema, administration at 200mg/kg (i.p.) of ethanolic extract from Asparagus cochinchinensis Merrill (ACE)expressed strong anti inflammatory effect through inhibited topical edema in the mouse ear, and substantial reductions in skin thickness and tissue weight, inflammatory cytokine production,.....

Dr. Lee DY, the lead author in the study said, "ACE is an effective anti-inflammatory agent in murine phorbol ester-induced dermatitis" and " the compound may have therapeutic potential in a variety of immune-related cutaneous diseases."

The study of pharmacological properties of Asparagus racemosus root extracts (AR), also addressed the potential used of extract formulation for topical and/or transdermal drug to provide anti-inflammatory activity, due to its significant attenuation involved in systemic inflammation, without causing toxicity to experiment monocytic leukemia cell line THP-1.

Furthermore, the extract from asparagus also exert an inhibitory effect on pro-inflammatory cytokines, namely interleukin 1β and tumour necrosis factor α, and on the production of nitric oxide in free radical-mediated lipid oxidation stimulated by lipopolysaccharide in regualed immune response in vitro.

Some researchers insisted the properties of anti inflammation of asparagus may also due to the presence of phytochemical saponin contents in comparison to group treated with crude saponin extracts in the rat paw-oedema and the control group.

Taking altogether, Asparagus may have a potential anti inflammatory effect in reduced risk and treatment od chronic inflammatory diseases. The efficacy is not due to single ingredient in the food but the whole food.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation by Lee DY1, Choo BK, Yoon T, Cheon MS, Lee HW, Lee AY, Kim HK.(PubMed)
(2) Anti-inflammatory activity of liposomes of Asparagus racemosus root extracts prepared by various methods by Plangsombat N1, Rungsardthong K2, Kongkaneramit L3, Waranuch N4, Sarisuta N5.(PubMed)
(3) Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagusracemosus on pro-inflammatory cytokine and corticosterone levels produced by stress by Kanwar AS1, Bhutani KK.(PubMed)
(4) Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants by Hassan HS1, Sule MI, Musa AM, Musa KY, Abubakar MS, Hassan AS.(PubMed)

Wednesday, 30 August 2017

Herbal Therapy: Chaste Tree Berry, the Best Anti Inflammatory Whole Food

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

According to the the Kyung Hee University, casticin a major compound found from Vitex species at doses of 1, 2, and 10mg/kg casticin via an i.p. injection to C57BL/6 mice, expressed a significant effect in inhibition the numbers of cells of neutrophils, macrophages, and lymphocytes through reduced the levels of proinflammatory cytokines and chemokines, as shown in the bronchoalveolar lavage Fluid (BALF), and lung histological analysis.

Further more, the tested compound also displayed a remarkably decreased the peribronchial thickening or bronchial wall thickening and perivascular inflammatory cells and the epithelium thickness in mice with lung inflammation, particular to chronic obstructive pulmonary disease (COPD).

In some newly found chemical compound isolated from Chaste tree berry, namely a phenylindene-type lignan, vitexdoin F (1), and three phenylnaphthalene-type lignans, vitexdoins G, H and I (2-4) in the testing of anti inflammatory activities, Compound 1 showed a significant inhibition on the nitric oxide (NO) production (IC50 4.17 μg/mL) in induced inflammation.

Other, in the evaluation of anti-arthritic activity of the extract of V. negundo seeds (EVNS) using Freund's complete adjuvant (CFA) induced arthritis (AA) in rat model, oral administrated rats showed a elevated anti inflammatory activities through suppressed paw edema, decreased the arthritis score, spleen index, and reversed the weight loss.

In fact, the efficacy of extract of Chaste tree berry in reduced inflammation may be resulted of suppressed expression of protein in regulated pro inflammatory cytokins in various inflammatory pathways.

Taking together, phytochemical compounds found in Chaste tree berry may exhibit strong anti inflammatory properties through ameliorated the protein involved expression of proinflammatory

cytokins.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model by Lee H1, Jung KH2, Lee H3, Park S4, Choi W5, Bae H6(PubMed)
(2) Anti-inflammatory and anti-osteoporotic lignans from Vitex negundo seeds by Zheng CJ1, Zhang XW2, Han T1, Jiang YP1, Tang JY3, Brömme D4, Qin LP5.(PubMed)