Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Friday, 14 July 2017

Food Therapy: Asparagus, the Antidepressant Natural Whole Food

In an oral administration of methanolic extract of roots of AR (MAR) of the doses of 100, 200 and 400 mg/kg daily for 7 days and then subjected to forced swim test(FST), the extract decreased immobility in FST and increased avoidance response in learned helplessness test (LH), indicating antidepressant activity.

Dr. said, " MAR has significant antidepressant activity and this effect is probably mediated through the serotonergic and the noradrenergic systems(involved neurotransmitter release in nervous system) and augmentation of antioxidant defenses"

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a love one, and illness. Over 30 million Americans suffer from depression and the amount is increasing in an alarming rate.

Other extract, such as Extracts of Asparagus cochinchinensis (AC) also expressed the anti depressive effects, through inhibited oxidative stress cause of neuro cell damage and improved cell signal repose and signal transmitting.

Some researchers suggested that antidepressant activity of Asparagus racemosus (AR) may also be mediated by the neurotransmitters system, and cgonitive activities possibly through the cholinergic system involved neuromuscular junctions, preganglionic neurons of the sympathetic nervous system....

Furthermore, the study also showed that AR may be used as food and have potential drug-drug, drug-food and food-food interactions with drugs and foods, sharing the cholinergic and monoaminergic pathways in sending message between neuro cells, induced protective activities against development of depression.

The efficacy of Asparagus in ameliorated depression through neuroprotective effect by inhibited free radical causes of neuro cell damage and improved cell signal response and signal transmitting may require further mutli and lager size studies to confirm its validation.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Antidepressant activity of Asparagus racemosus in rodent models by Singh GK1, Garabadu D, Muruganandam AV, Joshi VK, Krishnamurthy S.(PubMed)
(2) The neuroprotective effects and possible mechanism of action of a methanol extract from Asparagus cochinchinensis: In vitro and in vivo studies by Jalsrai A1, Numakawa T2, Kunugi H2, Dieterich DC3, Becker A4.(PubMed)
(3) Asparagus racemosus competitively inhibits in vitro the acetylcholine and monoamine metabolizing enzymes by Meena J1, Ojha R, Muruganandam AV, Krishnamurthy S.(PubMed)
(4) Behavioural and neurochemical evaluation of Perment an herbal formulation in chronic unpredictable mild stress induced depressive model by Ramanathan M1, Balaji B, Justin A.(PubMed)

Herbal Therapy: Cat's claw, The Whole Herb Medicine for Improving Immune Activities

Immunomodulatory compounds exerted the above properties found in cat's claw include ajoene, arctigenin, β-carotene, curcumin, epigallocatechin-3-gallate, ginsan, glabridin and quinic acid, according to Dr. Baraya YS, the lead researcher.

A herbal immunomodulators review, in vitro and in vivo, also suggested, cats claw expressed the regulation of informational molecules such as cytokines through alternation of immune function. Therefore, the medical plant may be a potential therapeutic modality for the treatment of many differing conditions involving cytokine, including inflammation and auto immune diseases.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

Auto immune diseases are the disorder caused by immune system attacks the body healthy cells.
Cat's claw (Uncaria tomentosa) may be the next medical plant used for treatment of auto immune diseases through its stimulated immune effects.

Severe dengue is a disease associated to the changes in the endothelial barrier function due to the production of inflammatory mediators by immune cells, U. tomentosa exerted antiviral and immunomodulatory activities in inhibition of antigen and proinflammatory cytokine.

In fact, the significant effect in immunomodulation may introduce Cat's claw, as a promising candidate for clinical application.

The use of this herbal plant should be taken with care as toxicity has been found in some cases of overdoses.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Uncaria tomentosa increases growth and immune activity in Oreochromis niloticus challenged with Streptococcus agalactiae by Yunis-Aguinaga J1, Claudiano GS2, Marcusso PF2, Manrique WG2, de Moraes JR3, de Moraes FR4, Fernandes JB1.(PubMed)
(2) The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review by Baraya YS1, Wong KK2, Yaacob NS3.(PubMed)
(3) Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators by Spelman K1, Burns J, Nichols D, Winters N, Ottersberg S, Tenborg M.(PubMed)
(4) Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2 by Reis SR1, Valente LM, Sampaio AL, Siani AC, Gandini M, Azeredo EL, D'Avila LA, Mazzei JL, Henriques Md, Kubelka CF.(PubMed)
(5) Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis by Valerio LG Jr1, Gonzales GF.(PubMed)

Thursday, 13 July 2017

Food Therapy: Asparagus, the Natural Whole Food for Reduced Risk and treatment of Ulcer

Intake Asparagus regularly may have a positive effect in reduced risk and treatment of ulcer.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

According to the University of Maiduguri, Methanolic extract of Asparagus pubescens root exerted protective against anti ulcer effects through regulating alpha(2)-adrenoceptor stimulation on vascular smooth muscle, in a dose-related manner.

In the study of Asparagus racemosus Willd. (methanolic extract) against indomethacin (a non-steroidal anti-inflammatory drug), induced gastric ulcers, oral administration of Asparagus racemosus (Shatavari) crude extract significantly reduced ulcerindex when compared with control group in doses of 100 mg/kg/day.

Dr. Bhatnagar M, the lead author said, " Crude extract also significantly reduced volume of gastric secretion, free acidity and total acidity..........( probably due to sparagus racemosus exerted) an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage".

In fact, asparagus anti gastric ulcer efficacy, can be observed through the significant increase of the total carbohydrate and total carbohydrate/protein ratio as well as reduced the ulcer index, volume of gastric secretion, free acidity, and total acidity.

Some researchers suggested, the anti ulcer activity of asparagus may also be a result of increased antioxidant in ameliorated damage of stomach lining caused by domino's effect of free radical production.

Sources
(1) Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats by Nwafor PA1, Okwuasaba FK, Binda LG.(PubMed)
(2) Antisecretory and antiulcer activity of Asparagus racemosus Willd. against indomethacin plus phyloric ligation-induced gastric ulcer in rats by Bhatnagar M1, Sisodia SS.(PubMed)

Food Therapy: Asparagus, the Natural Whole Food in Enhanced Male Reproductive Health

In a Rats study divided into five groups: Group I (control), Groups II-IV (AARR treated, 100, 200, and 300 mg/kg body weight, respectively, orally for 30 d) and Group V (standard control treated with sildenafil citrate, 5 mg/kg body weight), treatment of asparagus adscendens root (AARR) extract
group showed a significant increase of weight, testicular tubular diameter, the number of sperm counts and sexual behavioral parameters, including penile erections in comparison to other groups.

Dr. Bansode FW, the lead author said, "These results indicate increased anabolic, reproductive, and sexual activities by AARR treatment. Thus, the data provide scientific rationale for its traditional use as an aphrodisiac (in stimulates sexual desire) or for sexual disorders".

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

In vitro, Lyophilised aqueous extracts of Asparagus racemosus Willd. (AR) exerted a significant effect on the sperm counts, seminal fructose content and penile erection in improving male reproductive function.

Researchers also suggested that There is a directly correlated of erectile function with the penile effect of extracts on induced NO release.

Taking together, Asparagus may be the next potential whole food medicine for treatment of male sexual malfunction, including sexual desire, erectile dysfunction and infertility, etc., but further studies may be necessary.to confirm this potency.

Herbal Therapy: Cayenne, the Natural Whole Herb Medicine for treatment of Metabolic dysregulation

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
Many researchers has raised a question of their's effectiveness because of quality of the herbs due to geographic differences, time of grown and harvest, etc. I do believe that these questions can only be answered by experience herbalist.

Cayenne may be the next herbal medicine in reduced risk and treatment of metabolic dysregulation, recent study suggested

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.

Metabolic dysregulation refers to abnormal function of the body in regulation of glucose tolerance, fasting glucose, insulin resistance, dyslipidemia,...., leading to insulin resistance, type 2 diabetes, and fatty liver disease.

Capsaicin, the major chemical compound used dietary supplement attenuated metabolic dysregulation in genetically obese diabetic mice through by enhancing expression of modulation of glucose and lipid metabolism involving its receptors.

In obesity-induced inflammation and the development of obesity-related metabolic disorders, cayenne capsaicin suppressed inflammatory responses in inducing glucose intolerance and enhancing fatty acid oxidation in fat tissues, affecting insulin resistance.

The chemical compound involvement in reduced visceral adipose fat, also lowered serum levels of fasting glucose, total cholesterol, and triglycerides, probably through limited fat accumulation in adipose tissues and reduced inflammation and increased insulin sensitivity.

Dr. Leung FW. said," Clinical evidence supports a role of capsaicin as an anti-obesity agent. Both oral and gastrointestinal exposure to capsaicin increase satiety and reduce energy and fat intake and reduction in visceral abdominal fat" and "Thermogenesis and lipid metabolism-related proteins are altered upon capsaicin treatment in white adipose tissue".

Intake of cayenne for weight loss treatment induced reduction in visceral abdominal fat may also improve the metabolic regulation. Quality of doses should only be given by specialist to prevent toxicity.

Food Therapy: Celery, the Natural Whole Food in Ameliorated Pain of Dysmenorrhea

In the randomized, double-blind, placebo-controlled pilot trial among 180 female students at Isfahan University dormitory aged 18 to 27 who suffered from primary dysmenorrhea, the combination decode expressed significant reductions in pain scores and pain duration scores in the groups that took SCA (P < . 001), in comparison to group who took mefenamic acid, used to treat mild to moderate pain.

Dr. Nahid K, the researcher said, "The decrease in pain score was reflected by a significant reduction in other drug use among the treatment groups compared with the women in the placebo group" and "The magnitude of the reduction was significantly greater in the SCA group than in the mefenamic acid and placebo groups".

Usr-i-tamth in Unani (Greco-Arabic) decode, included celery, used in traditional medicine in treating pain associated with menstruation.

In the review of the Cochrane database, PubMed/Google Scholar, and other websites for articles on complementary and alternative medicine, the herbal formula exerted analgesic effect in attenuated abnormal temperament, menstrualirregularities/uterine diseases, particular in management of menstrual pain/dysmenorrhoea.

Although some herbal medicine and formula may have a powerful effect in ameliorated painful menstruation, further data collection is necessary to prevent adverse drug reactions among women using herbal medicines for reproductive health.

(2) Management of Usr-i-Tamth (Menstrual Pain) in Unani (Greco-Islamic) Medicine by Sultana A1, Lamatunoor S2, Begum M3, Qhuddsia QN4.(PubMed)
(3) Medicinal plants used for menstrual disorders in Latin America, the Caribbean, sub-Saharan Africa, South and Southeast Asia and their uterine properties: a review by van Andel T1, de Boer HJ2, Barnes J3, Vandebroek I4.(PubMed)

Wednesday, 12 July 2017

Herbal Therapy: Cinnamon: The Best Whole food Medicine for Prevention, management and Treatment of Cervical Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine), linking health benefits in prevention, management and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Cinnamon may be the Best Whole food Medicine for Prevention, management and Treatment of Cervical Cancer.
According to the Manipal University, Eugenol, a potential chemopreventive agent, one of the a component of cinnamon possesses antiseptic, analgesic, antibacterial, and anticancer properties in expression of apoptosis and inflammation against cervical cancer cell lines.

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

In SiHa cancer cell line, established from cancerous tissues of the cervix uteri, methanol extracts of Gymnema sylvestre (GS) leaves and Cinnamomum zeylanicum (CZ) bark exhibited dose-dependent cytotoxicity, inducing apoptosis.

Other researchers suggested that the effective use of cinnamon against tumor activity, particular in cervical cancer cell line SiHa may be the result in reduced number of colonies, risk of migration potential through down regulated normal physiological processes.

Dr. Kwon HK, the lead researcher at the Gwangju Institute of Science and Technolog, insisted, Cinnamomum cassia bark,.. containing several active components such as essential oils, expressed anti-tumor effect via enhanced pro-apoptotic and inhibition of pro inflammatory activities, in vitro and in vivo mouse melanoma model.

In fact, the potential anti-tumor effects of cinnamon may be due to increased anti-tumor activities in suppression of progression by increasing the levels of cytolytic molecules and cytotoxic activity.

Although the whole herb medicine may be a potential agent for reduced risk and treatment of cervical cancer, oral use of cinnamon should be taken with care and only prescribed by herbalist.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells by Hussain A1, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(PubMed)
(2) Biomolecule-loaded chitosan nanoparticles induce apoptosis and molecular changes in cancer cell line (SiHa) by Sujima Anbu A1, Velmurugan P2, Lee JH3, Oh BT4, Venkatachalam P5.(PubMed)
(3) Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential by Koppikar SJ1, Choudhari AS, Suryavanshi SA, Kumari S, Chattopadhyay S, Kaul-Ghanekar R.(PubMed)
(4) Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1 by Kwon HK1, Hwang JS, So JS, Lee CG, Sahoo A, Ryu JH, Jeon WK, Ko BS, Im CR, Lee SH, Park ZY, Im SH.(PubMed)
(5) Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells by Kwon HK1, Jeon WK, Hwang JS, Lee CG, So JS, Park JA, Ko BS, Im SH.(PubMed)