The Research and Studies of Musculo-Skeletal disorders(MSDs)- The Preventive Minerals - Selenium

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             The Preventive Minerals and Vitamins - Selenium



B.3. The Preventive Minerals and Vitamins
1. Minerals for osteoarthritis
Certain minerals such as calcium(316)(317), magnesium, selenium, zinc, and iron; may be a good sources of pain reliever for patient with osteoarthritis, according to the studies(325). According to the randomized to four double-blinded treatments for 12 weeks by Minnesota Applied Research Center, Glucosamine sulfate (1500 mg/d), Aquamin (2400 mg/d) and Combined treatment composed of Glucosamine sulfate (1500 mg/d) have shown effectively in improvements in symptoms of pain and stiffness of osteoarthritis(315).


1.3. Selenium
In male STR/1N mice model, dietary selenium and other vitamins not only is found to have an decreased risk of osteoartritis, OA, but also play an important role in prevention or therapy of mechanically induced OA(324). In deed, according to the joint study by College of Medicine of Xi'an Jiaotong University, alterations in selenium metabolism and apoptosis due to inability of MYC mediated metabolism and apoptosis signaling pathway may contribute to the pathogenesis of KBD, a special type of endemic osteoarthritis(326). Patient with osteoarthritis is found to have a low level of selenium in comparison to osteopororsis(323).



All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

References

(317) Calcium and vitamin D nutrition and bone disease of the elderly by Gennari C1.(PubMed)
(318) Calcium: An Important Nutrient that Builds Stronger Bones(Osteoarthritis Canada)
(319) Bone Health and Osteoporosis: A Report of the Surgeon General(NCBI)
(320) Association between Dietary Magnesium Intake and Radiographic Knee Osteoarthritis. by Zeng C1, Li H1, Wei J2, Yang T1, Deng ZH1, Yang Y1, Zhang Y1, Yang TB2, Lei GH1(PubMed)
(321) Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based study by Qin B1, Shi X, Samai PS, Renner JB, Jordan JM, He K.(PubMed)
(322) Relationship between Serum Magnesium Concentration and Radiographic Knee Osteoarthritis. by Zeng C1, Wei J1, Li H1, Yang T1, Zhang FJ1, Pan D1, Xiao YB1, Yang TB1, Lei GH2.(PubMed)
(323) Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis by Karaaslan F1, Mutlu M2, Mermerkaya MU1, Karaoğlu S3, Saçmaci Ş4, Kartal Ş4.(PubMed)
(324) Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice by Kurz B1, Jost B, Schünke M.(PubMed)
(325) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)
(326) Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis by Wu SX1, Wang WZ2, Zhang F3, Wu CY3, Dennis BS3, Qu CJ4, Bai YD5, Guo X6.(PubMed)
(327) Differences in zinc status between patients with osteoarthritis and osteoporosis by Ovesen J1, Møller-Madsen B, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Thomsen JS.(PubMed)
(328) Differences in zinc status, bone turnover and femoral head bone density and biomechanical properties between patients with osteoarthritis and osteoporosis by Thomsen JS1, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Møller-Madsen B, Ovesen J.(PubMed)
(329) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.
(330) Copper-salicylate gel for pain relief in osteoarthritis: a randomised controlled trial.
Shackel NA1, Day RO, Kellett B, Brooks PM.(PubMed)
(331) Serum copper and zinc in rheumatoid arthritis and osteoarthritis by Grennan DM, Knudson JM, Dunckley J, MacKinnon MJ, Myers DB, Palmer DG.(PubMed)
(332) Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis by Yassin NZ1, El-Shenawy SM1, Abdel-Rahman RF1, Yakoot M2, Hassan M3, Helmy S4.(PubMed)
(333) Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression ofosteoarthritis under mechanical stress by Camacho A1, Simão M2, Ea HK3, Cohen-Solal M3, Richette P3, Branco J4, Cancela ML5.(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs)- The Preventive Minerals - Magnesium

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             The Preventive Minerals and Vitamins - Magnesium

B.3. The Preventive Minerals and Vitamins
1. Minerals for osteoarthritis
Certain minerals such as calcium(316)(317), magnesium, selenium, zinc, and iron; may be a good sources of pain reliever for patient with osteoarthritis, according to the studies(325). According to the randomized to four double-blinded treatments for 12 weeks by Minnesota Applied Research Center, Glucosamine sulfate (1500 mg/d), Aquamin (2400 mg/d) and Combined treatment composed of Glucosamine sulfate (1500 mg/d) have shown effectively in improvements in symptoms of pain and stiffness of osteoarthritis(315).


1.2. Magnesium
According to the study by Central South University,dietary magnesium (Mg) of elder patients is associated to reduce risk of radiographic knee osteoarthritis (OA), joint space narrowing (JSN)(320), especially in white population(321).
According to joint study lead by Dr. Zeng C, Serum Magnesium Concentration is found to be deficient in patient with osteoarthritis(322). In deed, patient with osteoarthritis is found to have a decreased bone levels of Mg, in comparison of radiographic bone density and bone mineral density (BMD) in patient with Musculoskeletal disorders (MSDs)(323),



All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

References

(317) Calcium and vitamin D nutrition and bone disease of the elderly by Gennari C1.(PubMed)
(318) Calcium: An Important Nutrient that Builds Stronger Bones(Osteoarthritis Canada)
(319) Bone Health and Osteoporosis: A Report of the Surgeon General(NCBI)
(320) Association between Dietary Magnesium Intake and Radiographic Knee Osteoarthritis. by Zeng C1, Li H1, Wei J2, Yang T1, Deng ZH1, Yang Y1, Zhang Y1, Yang TB2, Lei GH1(PubMed)
(321) Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based study by Qin B1, Shi X, Samai PS, Renner JB, Jordan JM, He K.(PubMed)
(322) Relationship between Serum Magnesium Concentration and Radiographic Knee Osteoarthritis. by Zeng C1, Wei J1, Li H1, Yang T1, Zhang FJ1, Pan D1, Xiao YB1, Yang TB1, Lei GH2.(PubMed)
(323) Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis by Karaaslan F1, Mutlu M2, Mermerkaya MU1, Karaoğlu S3, Saçmaci Ş4, Kartal Ş4.(PubMed)
(324) Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice by Kurz B1, Jost B, Schünke M.(PubMed)
(325) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)
(326) Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis by Wu SX1, Wang WZ2, Zhang F3, Wu CY3, Dennis BS3, Qu CJ4, Bai YD5, Guo X6.(PubMed)
(327) Differences in zinc status between patients with osteoarthritis and osteoporosis by Ovesen J1, Møller-Madsen B, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Thomsen JS.(PubMed)
(328) Differences in zinc status, bone turnover and femoral head bone density and biomechanical properties between patients with osteoarthritis and osteoporosis by Thomsen JS1, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Møller-Madsen B, Ovesen J.(PubMed)
(329) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.
(330) Copper-salicylate gel for pain relief in osteoarthritis: a randomised controlled trial.
Shackel NA1, Day RO, Kellett B, Brooks PM.(PubMed)
(331) Serum copper and zinc in rheumatoid arthritis and osteoarthritis by Grennan DM, Knudson JM, Dunckley J, MacKinnon MJ, Myers DB, Palmer DG.(PubMed)
(332) Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis by Yassin NZ1, El-Shenawy SM1, Abdel-Rahman RF1, Yakoot M2, Hassan M3, Helmy S4.(PubMed)
(333) Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression ofosteoarthritis under mechanical stress by Camacho A1, Simão M2, Ea HK3, Cohen-Solal M3, Richette P3, Branco J4, Cancela ML5.(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs)- The Preventive Minerals - Calcium

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             Top Anti Inflammatory Foods - Ginger



B.3. The Preventive Minerals and Vitamins
1. Minerals for osteoarthritis
Certain minerals such as calcium(316)(317), magnesium, selenium, zinc, and iron; may be a good sources of pain reliever for patient with osteoarthritis, according to the studies(325). According to the randomized to four double-blinded treatments for 12 weeks by Minnesota Applied Research Center, Glucosamine sulfate (1500 mg/d), Aquamin (2400 mg/d) and Combined treatment composed of Glucosamine sulfate (1500 mg/d) have shown effectively in improvements in symptoms of pain and stiffness of osteoarthritis(315).
1.1. Calcium
The osteoporosis association of Canada recommended at 3 serving of milk and alternative serving of yogurt, cheese, calcium-fortified beverages, puddings, custards, etc for 50 plus elder(318). In deed, as we get older the function of replacement of osteoclasts in any areas of damaged or weakened bone are slower due to reduced process of bone remodelling(319) of which may involve the utilization of body in calcium aborption(319).


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

References

(317) Calcium and vitamin D nutrition and bone disease of the elderly by Gennari C1.(PubMed)
(318) Calcium: An Important Nutrient that Builds Stronger Bones(Osteoarthritis Canada)
(319) Bone Health and Osteoporosis: A Report of the Surgeon General(NCBI)
(320) Association between Dietary Magnesium Intake and Radiographic Knee Osteoarthritis. by Zeng C1, Li H1, Wei J2, Yang T1, Deng ZH1, Yang Y1, Zhang Y1, Yang TB2, Lei GH1(PubMed)
(321) Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based study by Qin B1, Shi X, Samai PS, Renner JB, Jordan JM, He K.(PubMed)
(322) Relationship between Serum Magnesium Concentration and Radiographic Knee Osteoarthritis. by Zeng C1, Wei J1, Li H1, Yang T1, Zhang FJ1, Pan D1, Xiao YB1, Yang TB1, Lei GH2.(PubMed)
(323) Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis by Karaaslan F1, Mutlu M2, Mermerkaya MU1, Karaoğlu S3, Saçmaci Ş4, Kartal Ş4.(PubMed)
(324) Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice by Kurz B1, Jost B, Schünke M.(PubMed)
(325) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)
(326) Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis by Wu SX1, Wang WZ2, Zhang F3, Wu CY3, Dennis BS3, Qu CJ4, Bai YD5, Guo X6.(PubMed)
(327) Differences in zinc status between patients with osteoarthritis and osteoporosis by Ovesen J1, Møller-Madsen B, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Thomsen JS.(PubMed)
(328) Differences in zinc status, bone turnover and femoral head bone density and biomechanical properties between patients with osteoarthritis and osteoporosis by Thomsen JS1, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Møller-Madsen B, Ovesen J.(PubMed)
(329) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.
(330) Copper-salicylate gel for pain relief in osteoarthritis: a randomised controlled trial.
Shackel NA1, Day RO, Kellett B, Brooks PM.(PubMed)
(331) Serum copper and zinc in rheumatoid arthritis and osteoarthritis by Grennan DM, Knudson JM, Dunckley J, MacKinnon MJ, Myers DB, Palmer DG.(PubMed)
(332) Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis by Yassin NZ1, El-Shenawy SM1, Abdel-Rahman RF1, Yakoot M2, Hassan M3, Helmy S4.(PubMed)
(333) Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression ofosteoarthritis under mechanical stress by Camacho A1, Simão M2, Ea HK3, Cohen-Solal M3, Richette P3, Branco J4, Cancela ML5.(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs)- HolisticTreatment with Diet modification - Nuts and seeds Olive

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             Diet modification - Nuts and seeds Olive

Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.


Olive Oil: Fat Content
1. Saturated fats
a. Palmitic acid
b. Stearic acid
c. Arachidic acid
d. ehenic acid
e. Myristic acid
f. Lignoceric acid
2. Unsaturated fat3. Monounsaturated fats
a. Oleic acid
b. Palmitoleic acid
3. Polyunsaturated fats
a. Linoleic acid
b. Linolenic acid


Monounsaturated fatty acids found abundantly in olive oil, may be beneficiary for reduced inflammation(362) and expression of lubricin to preserve the articular cartilage and then the entire joint, in rat model(362), as well as improving the disease associated loss of weight(363), such as osteoarthritis.
In a pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee, conducted by Ardabil University of Medical Science, researchers showed that the use of olive oil in the experiment is more effective than medical gel for knee osteoarthritis, probably due to its phytochemiocals oleuropein and hydroxy tyroso(364).


Other in the study of fruit and vegetable antioxidants of simple and polyphenols, showed that olive vegetation water (OVW) and its combination with glucosamine exhibit anti inflammatory processes, and may be considered as an effective therapyfor treatment of rheumatoid and osteoarthritis(365).In mechanical inflammatory arthritis (osteoarthritis, OA), The Olive leaf extract (OLE) also inhibit inflammatory process, including ear edema, myeloperoxidase (MPO) production, and may be beneficiary for the treatment of OA in humans(366).


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.htmlReferences

Angela M. Zivkovic, Natalie Telis, J. Bruce German, and Bruce D. Hammock(PubMed)
(362) Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression by Musumeci G, Trovato FM, Pichler K, Weinberg AM, Loreto C, Castrogiovanni P.(PubMed)
(363) Protective effects upon experimental inflammation models of a polyphenol-supplemented virgin olive oil diet by Martínez-Domínguez E1, de la Puerta R, Ruiz-Gutiérrez V.(PubMed)
(364) A pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee.in Bohlooli S1, Jastan M, Nakhostin-Roohi B, Mohammadi S, Baghaei Z.(PubMed)
(365) Hydrolyzed olive vegetation water in mice has anti-inflammatory activity by Bitler CM1, Viale TM, Damaj B, Crea R.(PubMed)
(366) Mechanisms of olive leaf extract-ameliorated rat arthritis caused by kaolin and carrageenan. by Gong D1, Geng C, Jiang L, Wang L, Yoshimura H, Zhong L.(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Top Anti Inflammatory Foods - Shiitake mushrooms

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     Top Anti Inflammatory Foods - Shiitake mushrooms



B.2. Diet modification according herbal and TCM medicine specialist
1. Top foods to reduce risk of inflammationLow-grade inflammation has found to play a pathophysiological role in OA, according to Dr. Jeremy Sokolove, Dr. Christin M. Lepus, OA is tightly linked to joint damage, the immune response to such damage, result of chronic inflammation causes of propagation and progression toward the disease(282).

According to Medical University Innsbruck, the relationship between diet, immunity, and the microbiota, may be necessary for us to rethink of the develop diet-based approaches to prevent or treat many diseases(283).

1.5. Shiitake mushrooms
Shiitake mushroom is an edible mushroom, genus Lentinula, belonging to family Marasmiaceae, native to East Asia and widely cultivated for consumption for its health benefits and commercial purpose in many Asian countries. Recent studies showed that Shiitake mushrooms are also consisted properties of enhanced immune system(309)(310)(311) against inflammation(312)(313) causes of chronic inflammatory diseases(314), etc..

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html


References

(282) Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations by Jeremy Sokolove and Christin M. Lepus(PubMed)
(283) Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease by Kirsty Brown,† Daniella DeCoffe,† Erin Molcan, and Deanna L. Gibson(PubMed)
(284) Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease by Hodge G1, Hodge S, Han P.(PubMed)
(285) Neuroprotective effect of allicin against traumatic brain injury via Akt/endothelial nitric oxide synthase pathway-mediated anti-inflammatory and anti-oxidative activities by Chen W1, Qi J2, Feng F3, Wang MD1, Bao G1, Wang T1, Xiang M3, Xie WF4.(PubMed)
(286) Anti-inflammatory activity of sulfur-containing compounds from garlic by Lee da Y1, Li H, Lim HJ, Lee HJ, Jeon R, Ryu JH.(PubMed)
(287) Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip by Drozdov VN1, Kim VA, Tkachenko EV, Varvanina GG.(PubMed)
(288) Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition , by Benzie IFF, Wachtel-Galor S, editors. Boca Raton (FL): CRC Press; 2011.(PubMed)
(289) Immunity: plants as effective mediators by Sultan MT1, Butt MS, Qayyum MM, Suleria HA.(PubMed)
(299) 6-Shogaol inhibits chondrocytes' innate immune responses and cathepsin-K activity by Villalvilla A1, da Silva JA, Largo R, Gualillo O, Vieira PC, Herrero-Beaumont G, Gómez R.(PubMed)
(290) Zingiber officinale: A Potential Plant against Rheumatoid Arthritis by Al-Nahain A1, Jahan R2, Rahmatullah M1.(PubMed)
(291) Theoretical and experimental study on lipophilicity and wound healingactivity of ginger compounds by Bakht MA1, Alajmi MF2, Alam P2, Alam A3, Alam P3, Aljarba TM3.(PubMed)
(292) A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans by Charron CS1, Dawson HD1, Albaugh GP1, Solverson PM1, Vinyard BT2, Solano-Aguilar GI1, Molokin A1, Novotny JA3.(PubMed)
(293) A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats by Qian Y1, Zhong P2, Liang D1, Xu Z1, Skibba M1, Zeng C3, Li X1, Wei T3, Wu L4, Liang G1.(PubMed)
(294) Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus by Motaghinejad M1, Karimian M2, Motaghinejad O3, Shabab B4, Yazdani I5, Fatima S2.(PubMed)
(295) Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis by Panahi Y1, Hosseini MS2, Khalili N2, Naimi E2, Majeed M3, Sahebkar A4.(PubMed)
(296) Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations by Nahar PP1, Slitt AL, Seeram NP.(PubMed)
(297) In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes by Reenu J1, Azeez S1, Bhageerathy C1.(PubMed)
(298) Polyphenolic composition and antioxidant activities of 6 new turmeric(Curcuma longa L) accessions by Chinedum E1, Kate E, Sonia C, Ironkwe A,Andrew I.(PubMed)
(299) Curcuma as a functional food in the control of cancer and inflammation by Schaffer M1, Schaffer PM, Zidan J, Bar Sela G.(PubMed)
(300) Curcumin induces apoptosis in breast cancer cell lines and delays the growth of mammary tumors in neu transgenic mice by Masuelli L1, Benvenuto M, Fantini M, Marzocchella L, Sacchetti P, Di Stefano E, Tresoldi I, Izzi V, Bernardini R, Palumbo C, Mattei M, Lista F, Galvano F, Modesti A, Bei R.(PubMed)
(301) Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects by He RR1, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H.(PubMed)
(302) Thermogenic ingredients and body weight regulation by Hursel R1, Westerterp-Plantenga MS.(PubMed)
(303) Determination of tea components with antioxidant activity by Cabrera C1, Giménez R, López MC.(PubMed)
(304) Structural determination and DPPH radical-scavenging activity of two acylated flavonoid tetraglycosides in oolong tea (Camellia sinensis) by Lee VS1, Chen CR, Liao YW, Tzen JT, Chang CI.(PubMed)
(305) Evaluation of anti-inflammatory effects of green tea and black tea: A comparative in vitro study by Chatterjee P1, Chandra S, Dey P, Bhattacharya S.(PubMed)
(306) Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells by Cavet ME1, Harrington KL, Vollmer TR, Ward KW, Zhang JZ.(PubMed)
(307) Immunomodulatory effects of EGCG fraction of green tea extract in innate and adaptive immunity via T regulatory cells in murine model by Kuo CL1, Chen TS, Liou SY, Hsieh CC.(PubMed)
(308) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(309) Structure and inducing tumor cell apoptosis activity of polysaccharides isolated from Lentinus edodes by Wang KP1, Zhang QL, Liu Y, Wang J, Cheng Y, Zhang Y.(PubMed)
(310) Structure and immuno-stimulating activities of a new heteropolysaccharide from Lentinula edodes by Xu X1, Yan H, Zhang X.(PubMed)
(311) Dietary supplementation with rice bran fermented with Lentinus edodes increases interferon-γ activity without causing adverse effects: a randomized, double-blind, placebo-controlled, parallel-group study by Choi JY, Paik DJ, Kwon DY, Park Y1.(PubMed)
(312) Anti-inflammatory effects of five commercially available mushroomspecies determined in lipopolysaccharide and interferon-γ activated murine macrophages by Gunawardena D1, Bennett L, Shanmugam K, King K, Williams R, Zabaras D, Head R, Ooi L, Gyengesi E, Münch G.(PubMed)
(313) Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise by Zembron-Lacny A1, Gajewski M, Naczk M, Siatkowski I.(PubMed)
(314) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR1.(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs)- HolisticTreatment with Diet modification - Cold water fish Salmon

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             Diet modification - Cold water fish Salmon



B.2. Diet modification according herbal and TCM medicine specialist

2. Cold water fish Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die.

Nutrients
1. Protein
2. Omega-3 fatty acids
3. B vitamins
4. Vitamin D
5. Astaxanthin
is a potent antioxidant that stimulates the development of healthy fish nervous systems and enhances the fish's fertility and growth rate.
6. Selenium
7. Tryptophan
8. Magnesium
9. Phosphorus
10. Etc.

Intake of salmon calcitonin, a hormone produced by the thyroid gland of salmon or a synthetic polypeptide of the same sequence found in salmon(360) has shown to reduce OA pathogenesis and bone resorption, according to the study of 10 7-month-old female Sprague Dawley rat model by Nordic Bioscience A/S at Danmark(354) and counteract of type II collagen (CII), degradation and related surface erosions of articular cartilage in ovariectomized rat model(355), probably through the effects of subchondral trabecular bone changes and on osteoarthritic cartilage lesions(356). The change of both markers of bone and cartilage degradation in osteoarthritis has made salmon calitonin a potential new treatment opportunities for OA(358).
In treatment of symptomatic knee osteoarthritis, intake of salmon calcitonin showed an effect on sum of pain, function, stiffness, and total scores, the biomarkers of bone and joint metabolism but not in patients with symptomatic knee OA(357), according to 2 phase of 3 trials study by Nordic Bioscience, Denmark.
According to the Université Catholique de Louvain, oral salmon calcitonin, also improved functional disability and reduced levels of biomarkers of which can predict of joint space narrowing induced cartilage loss(359).
The high amount of Omega 3 fatty acid also make salmon of the dietary nutrients for the modulation of inflammation and metabolic health including prevention reduced risk of progression of osteoarthritis(361).




All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.htmlReferences

(354) Oral salmon calcitonin reduces cartilage and bone pathology in an osteoarthritis rat model with increased subchondral bone turnover by Nielsen RH1, Bay-Jensen AC, Byrjalsen I, Karsdal MA.(PubMed)
(355) The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model by Sondergaard BC1, Oestergaard S, Christiansen C, Tankó LB, Karsdal MA.(PubMed)
(356) Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency by Behets C1, Williams JM, Chappard D, Devogelaer JP, Manicourt DH.(PubMed)
(357) Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials by Karsdal MA1, Byrjalsen I2, Alexandersen P3, Bihlet A2, Andersen JR2, Riis BJ2, Bay-Jensen AC2, Christiansen C2; CSMC021C2301/2 investigators.(PubMed)
(358) Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis--the effect of sex, Kellgren-Lawrence (KL) score, body mass index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation by Karsdal MA1, Byrjalsen I, Bay-Jensen AC, Henriksen K, Riis BJ, Christiansen C.(PubMed)
(359) Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis by Manicourt DH1, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP.(PubMed)
(360) Calcitonin(The free dictionary)
(361) Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic healt by Angela M. Zivkovic, Natalie Telis, J. Bruce German, and Bruce D. Hammock(PubMed)

The Research and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Top Anti Inflammatory Foods - Green tea

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                             Top Anti Inflammatory Foods - Green tea



B.2. Diet modification according herbal and TCM medicine specialist
1. Top foods to reduce risk of inflammationLow-grade inflammation has found to play a pathophysiological role in OA, according to Dr. Jeremy Sokolove, Dr. Christin M. Lepus, OA is tightly linked to joint damage, the immune response to such damage, result of chronic inflammation causes of propagation and progression toward the disease(282).

According to Medical University Innsbruck, the relationship between diet, immunity, and the microbiota, may be necessary for us to rethink of the develop diet-based approaches to prevent or treat many diseases(283).

1.4. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, green tea has been cultivated for commercial purposes all over the world. Epidemiological studies suggested that green tea induced weight loss(301)(302), improved chronic inflammatory diseases through its antioxidant(303)(304), anti inflammatory(305)(306) and immune modulatory(307)(308) activities.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html


References

(282) Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations by Jeremy Sokolove and Christin M. Lepus(PubMed)
(283) Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease by Kirsty Brown,† Daniella DeCoffe,† Erin Molcan, and Deanna L. Gibson(PubMed)
(284) Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease by Hodge G1, Hodge S, Han P.(PubMed)
(285) Neuroprotective effect of allicin against traumatic brain injury via Akt/endothelial nitric oxide synthase pathway-mediated anti-inflammatory and anti-oxidative activities by Chen W1, Qi J2, Feng F3, Wang MD1, Bao G1, Wang T1, Xiang M3, Xie WF4.(PubMed)
(286) Anti-inflammatory activity of sulfur-containing compounds from garlic by Lee da Y1, Li H, Lim HJ, Lee HJ, Jeon R, Ryu JH.(PubMed)
(287) Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip by Drozdov VN1, Kim VA, Tkachenko EV, Varvanina GG.(PubMed)
(288) Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition , by Benzie IFF, Wachtel-Galor S, editors. Boca Raton (FL): CRC Press; 2011.(PubMed)
(289) Immunity: plants as effective mediators by Sultan MT1, Butt MS, Qayyum MM, Suleria HA.(PubMed)
(299) 6-Shogaol inhibits chondrocytes' innate immune responses and cathepsin-K activity by Villalvilla A1, da Silva JA, Largo R, Gualillo O, Vieira PC, Herrero-Beaumont G, Gómez R.(PubMed)
(290) Zingiber officinale: A Potential Plant against Rheumatoid Arthritis by Al-Nahain A1, Jahan R2, Rahmatullah M1.(PubMed)
(291) Theoretical and experimental study on lipophilicity and wound healingactivity of ginger compounds by Bakht MA1, Alajmi MF2, Alam P2, Alam A3, Alam P3, Aljarba TM3.(PubMed)
(292) A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans by Charron CS1, Dawson HD1, Albaugh GP1, Solverson PM1, Vinyard BT2, Solano-Aguilar GI1, Molokin A1, Novotny JA3.(PubMed)
(293) A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats by Qian Y1, Zhong P2, Liang D1, Xu Z1, Skibba M1, Zeng C3, Li X1, Wei T3, Wu L4, Liang G1.(PubMed)
(294) Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus by Motaghinejad M1, Karimian M2, Motaghinejad O3, Shabab B4, Yazdani I5, Fatima S2.(PubMed)
(295) Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis by Panahi Y1, Hosseini MS2, Khalili N2, Naimi E2, Majeed M3, Sahebkar A4.(PubMed)
(296) Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations by Nahar PP1, Slitt AL, Seeram NP.(PubMed)
(297) In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes by Reenu J1, Azeez S1, Bhageerathy C1.(PubMed)
(298) Polyphenolic composition and antioxidant activities of 6 new turmeric(Curcuma longa L) accessions by Chinedum E1, Kate E, Sonia C, Ironkwe A,Andrew I.(PubMed)
(299) Curcuma as a functional food in the control of cancer and inflammation by Schaffer M1, Schaffer PM, Zidan J, Bar Sela G.(PubMed)
(300) Curcumin induces apoptosis in breast cancer cell lines and delays the growth of mammary tumors in neu transgenic mice by Masuelli L1, Benvenuto M, Fantini M, Marzocchella L, Sacchetti P, Di Stefano E, Tresoldi I, Izzi V, Bernardini R, Palumbo C, Mattei M, Lista F, Galvano F, Modesti A, Bei R.(PubMed)
(301) Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects by He RR1, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H.(PubMed)
(302) Thermogenic ingredients and body weight regulation by Hursel R1, Westerterp-Plantenga MS.(PubMed)
(303) Determination of tea components with antioxidant activity by Cabrera C1, Giménez R, López MC.(PubMed)
(304) Structural determination and DPPH radical-scavenging activity of two acylated flavonoid tetraglycosides in oolong tea (Camellia sinensis) by Lee VS1, Chen CR, Liao YW, Tzen JT, Chang CI.(PubMed)
(305) Evaluation of anti-inflammatory effects of green tea and black tea: A comparative in vitro study by Chatterjee P1, Chandra S, Dey P, Bhattacharya S.(PubMed)
(306) Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells by Cavet ME1, Harrington KL, Vollmer TR, Ward KW, Zhang JZ.(PubMed)
(307) Immunomodulatory effects of EGCG fraction of green tea extract in innate and adaptive immunity via T regulatory cells in murine model by Kuo CL1, Chen TS, Liou SY, Hsieh CC.(PubMed)
(308) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(309) Structure and inducing tumor cell apoptosis activity of polysaccharides isolated from Lentinus edodes by Wang KP1, Zhang QL, Liu Y, Wang J, Cheng Y, Zhang Y.(PubMed)
(310) Structure and immuno-stimulating activities of a new heteropolysaccharide from Lentinula edodes by Xu X1, Yan H, Zhang X.(PubMed)
(311) Dietary supplementation with rice bran fermented with Lentinus edodes increases interferon-γ activity without causing adverse effects: a randomized, double-blind, placebo-controlled, parallel-group study by Choi JY, Paik DJ, Kwon DY, Park Y1.(PubMed)
(312) Anti-inflammatory effects of five commercially available mushroomspecies determined in lipopolysaccharide and interferon-γ activated murine macrophages by Gunawardena D1, Bennett L, Shanmugam K, King K, Williams R, Zabaras D, Head R, Ooi L, Gyengesi E, Münch G.(PubMed)
(313) Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise by Zembron-Lacny A1, Gajewski M, Naczk M, Siatkowski I.(PubMed)
(314) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR1.(PubMed)