Kyle J. Norton
The widespread of prostate cancer, once considered a disease of aging
male, now have become major concerns of governments and scientific
community in South East Asian with tendency to effect even younger age
population. Suggestions emerged of over consuming bad fats in any time
in history accompanied with unhealthy diet and life style may be the
possible causes of the disease, linking to the economic prosperity over 2
decades. Foods for diseases' management have been prescribed in folk
medicine over thousands of year as one of best medicine of nature in
preventing and treating diseases, including prostate cancer.
Prostate cancer is defined as a condition in which the cells of
prostate has become cancerous, causing abnormal cell growth with
possibility of spreading to the distant parts of the body. Most
prostate cancers are slow growing and enlarged prostate and prostate
cancer may be detected during physical (rectum) exams.
The top 8 foods for reducing prostate cancer risk
1. Flaxseed
Flax seed is native to the region
of the eastern Mediterranean to India and also known as common flax or
linseed. Flax is an erect annual plant, it can grow to 1.2 m tall. The
leaves are 20–40 mm long and 3 mm broad.
Enterolactone and enterodiol, mammalian lignans derived from dietary flaxseed may obstruct or delay the progressed prostate cancer
cell proliferation via vascular endothelial growth
factor(VEGF)-associated pathways(76). Other study indicated that diet
supplemented with 5% flaxseed inhibits the growth and development of prostate cancer in the TRAMP model(77) and Flaxseed-supplemented
diet showed to lower prostate cancer proliferation rates and associated
with biological alterations that may be protective for prostate cancer(78).
2. Vegetable oil
Vegetables oil is a triglyceride extracted from a plant.
Increased levels of MUFA-rich vegetable oil((including olive oil, canola or peanut oil)) intake were associated with a progressive reduction in prostate cancer risk(79). Hydrogenated soybean oil (SHSO) showed remarkably strong anticarcinogenic activity against prostate cancer in the rat model and 5% dietary supplementation with SHSO inhibited the growth of prostate cancer by 80% in vivo(80).
3. Honey
The rich golden liquid is the
miraculous product made by bees using nectar from flowers. It is
considered as one of healthy sweet food for replacing the use of white
sugar and artificial sweetener by many people.
Chrysin, a natural flavone commonly found in honey, and honey itself showed to exert its antiproliferative effect on PC-3 cells in a dose- and time-dependent manner(81)
4. Chickpea
Garbanzo beans also known as chickpea is an edible legume of genus Cicer
and the family Fabaceae, high in protein and minerals. It is one of the
earliest cultivated vegetables, native to Middle East.
7 protease inhibitor concentrates (PICs) isolated from chickpea showed a significant inhibition the LNCaP prostate cancer cells in concentrations tested of 25-400 μg/ml(82).
5. Olive oil
Extra virgin olive oil (EVOO), was found
to significantly affect the growth of HCT 116 tumours xenografted in
athymic mice(83). Polyphenols, found in Extra virgin olive oil
(EVOO), exerted chemopreventive effects towards different organ
specific cancers,
affecting the overall process of carcinogenesis by
inhibition of DNA synthesis, modulation of ROS production, regulation of
cell cycle arrest, modulation of survival/proliferation pathways(84).
Other study suggested that Polyphenols can directly interact with
specific steps and/or proteins
regulating the apoptotic process in different ways depending on their
concentration, the cell system, the type or stage of the pathological
process(85).
6. Black pepper
Black pepper, is a flowering vine in the family Piperaceae, its fruits used as a spice and
seasoning
Piperine, a major alkaloid constituent of black pepper, inhibited the proliferation of LNCaP, PC-3, 22RV1 and DU-145 prostate cancer
cells in a dose dependent manner and induced apoptosis resulted in
caspase activation in LNCaP and PC-3 cells(86). β-caryophyllene oxide
(CPO), a sesquiterpene isolated from essential oils of medicinal plants
such as
guava (Psidium guajava), oregano (Origanum vulgare L.), cinnamon
(Cinnamomum spp.) clove (Eugenia caryophyllata), and black pepper
(Piper nigrum L.) not only inhibited the constitutive activation of
PI3K/AKT/mTOR/S6K1 (anti-apoptosis and increased cell proliferation and
nutrient–hormonal signaling network) pathway
signaling cascade but also down-regulated the expression of various
downstream gene products
that mediate cell proliferation (cyclin D1), survival (bcl-2, bcl-xL,
survivin, IAP-1, and IAP-2), metastasis (COX-2), angiogenesis (VEGF),
and increased the expression of p53 and p21(87).
7. Green tea
Green
tea containing more amount of antioxidants than any drinks or food with
the same volume, is the leaves of Camellia sinensis, undergone
minimal oxidation during processing, originated from China. Green tea
has been a precious drink in traditional Chinese culture and used
exceptional in socialization for more than 4000 thousand years. Because
of their health benefits, they have been cultivated for commercial
purposes all over the world.
Green tea
catechins (GTCs), a potent chemical constituent
containing (-)-epigallocathechin, (-)-epicatechin,
(-)-epigallocatechin-3-gallate, (-)-epicatechin-3-gallate, in treatment
of preprostate cancer men reduced lower urinary tract symptoms, improved
coexistent benign prostate hyperplasia and reached a statistical significance in the case of International Prostate Symptom Scores(88).
In green tea
polyphenols study, epigallocatechin-3-gallate (EGCG) exerted its anti
cancer effect on signaling pathways in PCa(89). Also combination
admiration of quercetin and green tea,
showed a significant increase in the inhibition of proliferation,
androgen receptor and phosphatidylinositol 3-kinase/Akt signaling(tumor
genesis in early stage), and stimulation of apoptosis(90). In short,
Green tea, a potent anti prostate cancer with activities of heritable
alterations of gene expression and chromatin organization without
changes in DNA sequence induced multistep process of carcinogenesis(91)
may be considered as a natural treatment in vary types of cancer.
8. Fermented soybean products
Fermented soybean products are made from fermenting soybeans and filamentous fungus, along with water and salt after a period of sometime.
In the Japan, incidence
of prostate caner in aging men are low compared with the Western
world, suggestion of these result may be tradition Japanese diet
related. Consumption of fish, all soybean products, tofu (bean curds), and natto (fermented soybeans)
was associated with decreased risk of ORs (Estimates of age-adjusted
odds ratios) which supported traditional Japanese diet rich in soybean products and fish against prostate cancer(92). In China, suggestion of reduced risk of prostate cancer
associated with consumption of soy foods and isoflavones found
abundantly in fermented soybean products(93). Unfortunately, the
epidemiological data, linking ferment soybean products to reduced risk
of prostate cancer are inconsistent including miso.
The prevalence and widespread of prostate cancer may be diet,
demographic and life style related disease(94)(95)(96). Suggestions and
intentions are for prevention of prostate cancer to develop in the first
place or used conjunction with conventional medicine in treating the
disease. Eating healthy, with plenty of vegetables and fruits has always
been considered as a preventive engagement in human history. "Let foods
be your medicine and let medicine be your foods" by Greek physician
Hippocrates (460-377 BC).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Most common Types of Cancer http://kylejnorton.blogspot.ca/p/blog-page.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(76) Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer by Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W.(PubMed)
(77) Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice BY Lin X, Gingrich JR, Bao W, Li J, Haroon ZA, Demark-Wahnefried W.(PubMed)
(78) Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer
proliferation rates in men presurgery by Demark-Wahnefried W, Polascik
TJ, George SL, Switzer BR, Madden JF, Ruffin MT 4th, Snyder DC, Owzar K,
Hars V, Albala DM, Walther PJ, Robertson CN, Moul JW, Dunn BK, Brenner
D, Minasian L, Stella P, Vollmer RT.(PubMed)
(79) Men who consume vegetable oils rich in monounsaturated fat: their dietary patterns and risk of prostate cancer (New Zealand) by Norrish AE, Jackson RT, Sharpe SJ, Skeaff CM.(PubMed)
(80) Selectively hydrogenated soybean oil exerts strong anti-prostate cancer activities by Jung MY, Choi NJ, Oh CH, Shin HK, Yoon SH.(PubMed)
(81) Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3 by Samarghandian S, Afshari JT, Davoodi S.(PubMed)
(82)Chickpea (Cicer arietinum) and other plant-derived protease inhibitor concentrates inhibit breast and prostate cancer cell proliferation in vitro. by Magee PJ, Owusu-Apenten R, McCann MJ, Gill CI, Rowland IR.(PubMed)
(83) Analgesic, anti-inflammatory and anticancer activities of extra virgin olive oil by Fezai M, Senovilla L, Jemaà M, Ben-Attia M(PubMed).
(84) Modulatory effects of polyphenols on apoptosis induction: relevance for cancer prevention by D'Archivio M, Santangelo C, Scazzocchio B, Varì R, Filesi C, Masella R, Giovannini C.(PubMed)
(85) Apoptosis in cancer and atherosclerosis: polyphenol activities by Giovannini C, Scazzocchio B, Varì R, Santangelo C, D'Archivio M, Masella R.(PubMed)
(86) Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer
Cells by Samykutty A, Shetty AV, Dakshinamoorthy G, Bartik MM, Johnson
GL, Webb B, Zheng G, Chen A, Kalyanasundaram R, Munirathinam G.(PubMed)
(87) β-Caryophyllene oxide inhibits growth and induces apoptosis through
the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs
activation by Park KR, Nam D, Yun HM, Lee SG, Jang HJ, Sethi G, Cho SK, Ahn KS.(PubMed)
(88) Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate
intraepithelial neoplasia: a preliminary report from a one-year
proof-of-principle study by Bettuzzi S, Brausi M, Rizzi F, Castagnetti
G, Peracchia G, Corti A.(PubMed)
(89) Modulation of signaling pathways in prostate cancer by green tea polyphenols by Khan N, Mukhtar H.(PubMed)
(90)Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea by Wang P, Vadgama JV, Said JW, Magyar CE, Doan N, Heber D, Henning SM.(PubMed)
(91) Epigenetic effects of green tea polyphenols in cancer by Henning SM, Wang P, Carpenter CL, Heber D.(PubMed)
(92) A case-control study of diet and prostate cancer
in Japan: possible protective effect of traditional Japanese diet by
Sonoda T, Nagata Y, Mori M, Miyanaga N, Takashima N, Okumura K, Goto K,
Naito S, Fujimoto K, Hirao Y, Takahashi A, Tsukamoto T, Fujioka T, Akaza
H.(PubMed)
(93) Soy and isoflavone consumption in relation to prostate cancer risk in China by Lee MM, Gomez SL, Chang JS, Wey M, Wang RT, Hsing AW.(PubMed)
(94) Soy intake and cancer risk: a review of the in vitro and in vivo data by Messina MJ, Persky V, Setchell KD, Barnes S.(PubMed)
(94) Mediterranean Diet and Prostate Cancer
Risk and Mortality in the Health Professionals Follow-up Study by
Kenfield SA, Dupre N, Richman EL, Stampfer MJ, Chan JM, Giovannucci EL.(PubMed)
(95) A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii by Severson RK, Nomura AM, Grove JS, Stemmermann GN.(PubMed)
(96) Alcohol consumption, smoking, and other risk factors and prostate cancer in a large health plan cohort in California (United States) by Hiatt RA, Armstrong MA, Klatsky AL, Sidney S.(PubMed)
Wednesday, 6 May 2015
The best weightloss and healthy recipe: Fancy rice salad
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Turn leftover rice into this yummy dish. Serve on lettuce with a roll
Cooked rice, cold 1 cup (250ml)
Crushed pineapple, drained4 oz. (398 ml)
Granulated sugar 1/4 cup (50ml)
Whipping cream ( or 1 envelope topping) 1 cup (250 ml)
Salad dressing ( or Mayonnaise) 1/4 cup (50ml)
Lettuce
Maraschino cherries
Combine rice, pineapple and sugar in a bowl. Stir
Beat cream until stiff. Beat in salad dressing. Fold into rice mixture.
Arrange lettuce on plates. Spoon salad in center. Top with a cherry. Serve 6.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Turn leftover rice into this yummy dish. Serve on lettuce with a roll
Cooked rice, cold 1 cup (250ml)
Crushed pineapple, drained4 oz. (398 ml)
Granulated sugar 1/4 cup (50ml)
Whipping cream ( or 1 envelope topping) 1 cup (250 ml)
Salad dressing ( or Mayonnaise) 1/4 cup (50ml)
Lettuce
Maraschino cherries
Combine rice, pineapple and sugar in a bowl. Stir
Beat cream until stiff. Beat in salad dressing. Fold into rice mixture.
Arrange lettuce on plates. Spoon salad in center. Top with a cherry. Serve 6.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Tuesday, 5 May 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Insulin resistance improvement and/or anti metabolic syndrome herb: Alfalfa
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Insulin resistance improvement and/or anti metabolic syndrome herbs
Alfalfa(1054)
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc. North American aboriginal has used Alfalfa seed as food, such as making bread and mush(1054).
Nutrients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
13. Flavones
14. Isoflavones
15. Sterols
16. Derivatives of coumarin
17. Etc.
In diabetes, alfalfa exhibited prevention of the onset of developing Type 1 Diabetes(1056)
diabetogenic or anti-diabetic potentials(1055), through its estrogenic activity in modulation of diabetes(1055), protection against pancreas from autoimmune destruction(1056), antihyperglycaemic, insulin-releasing and insulin-like activity(1057).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1055) Genistein modulation of streptozotocin diabetes in male B6C3F1 mice can be induced by diet by Guo TL1, Wang Y2, Xiong T3, Ling X4, Zheng J5.(PubMed)
(1056) Genistein Protects Female Nonobese Diabetic Mice from Developing Type 1 Diabetes When Fed a Soy- and Alfalfa-free Diet by Guo TL1, Germolec DR2, Zheng JF3, Kooistra L4, Auttachoat W3, Smith MJ3, White KL3, Elmore SA2.(PubMed)
(1057)Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM1, Flatt PR.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Insulin resistance improvement and/or anti metabolic syndrome herbs
Alfalfa(1054)
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc. North American aboriginal has used Alfalfa seed as food, such as making bread and mush(1054).
Nutrients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
13. Flavones
14. Isoflavones
15. Sterols
16. Derivatives of coumarin
17. Etc.
In diabetes, alfalfa exhibited prevention of the onset of developing Type 1 Diabetes(1056)
diabetogenic or anti-diabetic potentials(1055), through its estrogenic activity in modulation of diabetes(1055), protection against pancreas from autoimmune destruction(1056), antihyperglycaemic, insulin-releasing and insulin-like activity(1057).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1055) Genistein modulation of streptozotocin diabetes in male B6C3F1 mice can be induced by diet by Guo TL1, Wang Y2, Xiong T3, Ling X4, Zheng J5.(PubMed)
(1056) Genistein Protects Female Nonobese Diabetic Mice from Developing Type 1 Diabetes When Fed a Soy- and Alfalfa-free Diet by Guo TL1, Germolec DR2, Zheng JF3, Kooistra L4, Auttachoat W3, Smith MJ3, White KL3, Elmore SA2.(PubMed)
(1057)Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM1, Flatt PR.(PubMed)
The best weightloss and healthy recipe: Carrot raisin salad
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
A lunch box winner
Grated carrot 2 cups (500 ml)
Raison (see note) 1/2 cup (125 ml)
Salad dressing ( or mayonnaise) 1/3 cup (75 ml)
Vinegar 1tbsp. 15 ml
Put all ingredients into a bowl. Toss to coat. Serve 6.
Note: If raisins are too dry. Covered in equal amount of water to 2 minutes. Let stand until cool. Drain. Pat dry with paper towel.
Variation: Add 1/2 cup (125 ml) chopped celery.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
A lunch box winner
Grated carrot 2 cups (500 ml)
Raison (see note) 1/2 cup (125 ml)
Salad dressing ( or mayonnaise) 1/3 cup (75 ml)
Vinegar 1tbsp. 15 ml
Put all ingredients into a bowl. Toss to coat. Serve 6.
Note: If raisins are too dry. Covered in equal amount of water to 2 minutes. Let stand until cool. Drain. Pat dry with paper towel.
Variation: Add 1/2 cup (125 ml) chopped celery.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Monday, 4 May 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Insulin resistance improvement and/or anti metabolic syndrome herb: Astragalus
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Insulin resistance improvement and/or anti metabolic syndrome herbs
Astragalus (Astragalus membranaceus)(1045)
Huang Qi or Bei Qi is also known as Astragalus root. The sweet herb has been used as diuretic agent and to lower blood pressure, increase blood pressure, lessens proteinuria, improve endurance, protect liver function, regulate blood sugar, etc. as it tonifies Qi, raises Yang, strengthens the Defensive-Qi and the Exterior, expels toxins, etc. by enhancing the functions of lung and spleen channels(1045).
Ingredients
1. Astragaloside I,
2. Astragaloside II,
3. Daucosterol,
3. Beta-sitosterol,
4. Palmitic acid
5. Astragalus saponin A,B,C
6. Astramenbrangenin
7. Kumatakenin,
8. Choline,
9. Betaine,
10. Folic acid
11. Calyxosin,
12. Formononetin,
13. Cycloastragenol,
14. Astragaloside III,IV
15. Antibacterial ingredient,
16. L-3-hydroxy-9-methoxpterocarpan
17. Etc.
Epidemiological studies showed that stragalus polysaccharides (APS) ameliorates insulin resistance(1046)(1047) (IR) in rat cells and to elucidate the associated mechanisms, including increasing adiponectin secretion and reducing IL-6 secretion(1046), decreasing myostatin expression(1047), improving beta cell function(1049), regulating insulin signaling in insulin-resistant skeletal muscle(1047)(1048). insulin resistance related mRNA expression(1049), etc.
In metabolic syndrome, including increased body weight(1050), mild hypertension(1050), hyper insulinemia(1050), hyper triglyceridemia(1050), impaired glucose tolerance(1050)(1053) and impaired endothelium-dependent vasorelaxation(1050)(1051)(1052), astragaloside IV, a major constituent found in astragalus showed effectively in ameliorating metabolic syndrome(1050)(1052), probably through its antioxidant(1051), inhibition of abnormal TNF-alpha-induced intracellular free Ca(2+) accumulation in endothelial cells(1052), decreasing the elevated expression and activity in the skeletal muscles(1053).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1045) Huang Qi(Complementary and Alternative Healing University)
(1046) Amelioration of insulin resistance in rat cells by Astragalus polysaccharides and associated mechanisms by Liu H1, Bai J2, Weng X3, Wang T3, Li M1.(PubMed)
(1047) Astragalus polysaccharide suppresses skeletal muscle myostatin expression in diabetes: involvement of ROS-ERK and NF-κB pathways by Liu M1, Qin J2, Hao Y3, Liu M4, Luo J5, Luo T4, Wei L6.(PubMed)
(1048) Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle by Liu M1, Wu K, Mao X, Wu Y, Ouyang J.(PubMed)
(1049) A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice by Gao LH1, Liu Q1, Liu SN1, Chen ZY1, Li CN1, Lei L1, Sun SJ1, Li LY1, Liu JL1, Shen ZF2.(PubMed)
(1050) [Effects of Astragalus membranaceus and Potentilla discolor mixture on insulin resistance and its related mRNA expressions in KKAy mice with type 2 diabetes].[Article in Chinese] by Zhang DM1, Lou LX, Wu AM, Lü XY, Hu ZJ, Zhang YH, Liu HF.(PubMed)
(1051) Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation by Qiu LH1, Xie XJ, Zhang BQ.(PubMed)
(1052) Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro by Xu ME1, Xiao SZ, Sun YH, Ou-Yang Y, Zheng XX.(PubMed)
(1053) Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B by Wu Y1, Ou-Yang JP, Wu K, Wang Y, Zhou YF, Wen CY.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Insulin resistance improvement and/or anti metabolic syndrome herbs
Astragalus (Astragalus membranaceus)(1045)
Huang Qi or Bei Qi is also known as Astragalus root. The sweet herb has been used as diuretic agent and to lower blood pressure, increase blood pressure, lessens proteinuria, improve endurance, protect liver function, regulate blood sugar, etc. as it tonifies Qi, raises Yang, strengthens the Defensive-Qi and the Exterior, expels toxins, etc. by enhancing the functions of lung and spleen channels(1045).
Ingredients
1. Astragaloside I,
2. Astragaloside II,
3. Daucosterol,
3. Beta-sitosterol,
4. Palmitic acid
5. Astragalus saponin A,B,C
6. Astramenbrangenin
7. Kumatakenin,
8. Choline,
9. Betaine,
10. Folic acid
11. Calyxosin,
12. Formononetin,
13. Cycloastragenol,
14. Astragaloside III,IV
15. Antibacterial ingredient,
16. L-3-hydroxy-9-methoxpterocarpan
17. Etc.
Epidemiological studies showed that stragalus polysaccharides (APS) ameliorates insulin resistance(1046)(1047) (IR) in rat cells and to elucidate the associated mechanisms, including increasing adiponectin secretion and reducing IL-6 secretion(1046), decreasing myostatin expression(1047), improving beta cell function(1049), regulating insulin signaling in insulin-resistant skeletal muscle(1047)(1048). insulin resistance related mRNA expression(1049), etc.
In metabolic syndrome, including increased body weight(1050), mild hypertension(1050), hyper insulinemia(1050), hyper triglyceridemia(1050), impaired glucose tolerance(1050)(1053) and impaired endothelium-dependent vasorelaxation(1050)(1051)(1052), astragaloside IV, a major constituent found in astragalus showed effectively in ameliorating metabolic syndrome(1050)(1052), probably through its antioxidant(1051), inhibition of abnormal TNF-alpha-induced intracellular free Ca(2+) accumulation in endothelial cells(1052), decreasing the elevated expression and activity in the skeletal muscles(1053).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1045) Huang Qi(Complementary and Alternative Healing University)
(1046) Amelioration of insulin resistance in rat cells by Astragalus polysaccharides and associated mechanisms by Liu H1, Bai J2, Weng X3, Wang T3, Li M1.(PubMed)
(1047) Astragalus polysaccharide suppresses skeletal muscle myostatin expression in diabetes: involvement of ROS-ERK and NF-κB pathways by Liu M1, Qin J2, Hao Y3, Liu M4, Luo J5, Luo T4, Wei L6.(PubMed)
(1048) Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle by Liu M1, Wu K, Mao X, Wu Y, Ouyang J.(PubMed)
(1049) A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice by Gao LH1, Liu Q1, Liu SN1, Chen ZY1, Li CN1, Lei L1, Sun SJ1, Li LY1, Liu JL1, Shen ZF2.(PubMed)
(1050) [Effects of Astragalus membranaceus and Potentilla discolor mixture on insulin resistance and its related mRNA expressions in KKAy mice with type 2 diabetes].[Article in Chinese] by Zhang DM1, Lou LX, Wu AM, Lü XY, Hu ZJ, Zhang YH, Liu HF.(PubMed)
(1051) Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation by Qiu LH1, Xie XJ, Zhang BQ.(PubMed)
(1052) Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro by Xu ME1, Xiao SZ, Sun YH, Ou-Yang Y, Zheng XX.(PubMed)
(1053) Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B by Wu Y1, Ou-Yang JP, Wu K, Wang Y, Zhou YF, Wen CY.(PubMed)
The best weightloss and healthy recipe: No toss lettuce
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Choose iceberg lettuce or Chinese cabbage
Tarragon dressing
Sour cream 1/2 cup (125ml)
Tarragon vinegar 1tbsp. (15ml)
granulated sugar 2 tsp. (10ml)
Onion salt 1/2 tsp. (2ml)
Paprika 1/2 tsp. (2ml)
Salad
Lettuce chunks or wedges 6
Sliced green onion or thinly sliced onion ring 1/2 cup (125 ml)
Tarragon Dressing: Combined all 5 ingredients in a small bowl. Mix well
Salad: Arrange lettuce chunk on small size salad plate. Scatter onions over top. Spoon dressing over top, and serve. Serve 6
Variation: spoon French or thousand Island dressing over lettuce wedges.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Choose iceberg lettuce or Chinese cabbage
Tarragon dressing
Sour cream 1/2 cup (125ml)
Tarragon vinegar 1tbsp. (15ml)
granulated sugar 2 tsp. (10ml)
Onion salt 1/2 tsp. (2ml)
Paprika 1/2 tsp. (2ml)
Salad
Lettuce chunks or wedges 6
Sliced green onion or thinly sliced onion ring 1/2 cup (125 ml)
Tarragon Dressing: Combined all 5 ingredients in a small bowl. Mix well
Salad: Arrange lettuce chunk on small size salad plate. Scatter onions over top. Spoon dressing over top, and serve. Serve 6
Variation: spoon French or thousand Island dressing over lettuce wedges.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Sunday, 3 May 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb White willow
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: White willow
White willow is also known as salix alba in herbal medicine, native to Europe and western and central Asia, used in traditional medicine as pain reliever(1007)(1008), anticancer(1009)(1010), antimicrobial(1013), antioxidant(1014)(1015), anti-inflammatory(1011)(1012) and fertility enhancing herb(1016).
1, Antiestrigenic effects
White willow processes antiestrigenic effects(1017) by blocking proliferation in hypersensitive cells (1018) which cause estrogenic diseases, including breast cancer(1019) and metabolism imbalance(1020) diseases, such as obesity and diabetes(1021).
2. Salicylic acid
Salicylic acid, a chemical compound converted from salincin found abundantly in white willow has shown to process anti acne(1022)(1023) one of many symptoms of PCOs) effects, probably through its antioxidant activity(1026) in blocking elevated production of sebum by hyperactive sebaceous glands and blockage of the follicle(1022). According to Telemark Hospital, the acid may also be beneficiary for increased the clinical pregnancy rate when used conjunction with vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI)(1024) and protective against fetal losses(1025), through its anti antithrombotic property(1025). The synthetic version of salicylic acid has also shown to consisting aspirin's cardioprotective effects through its antithrombotic and anti-inflammatory actions(1027).
3. Immune system
The antioxidant(1028)(1029) and anti inflammatory(1030)(1031) effects of white willow enhance immune system fighting against microbial invasion and guarding our body DNA integrity(1033) against irregular cell growth(1032)(1033) through inhibiting the effect of intermediate enzymes and other mechanisms(1027)
d. Vitamin C
Natural vitamin polypeptide C white willow found in white willow not only is found to consist the weight loss property(See the weight loss vitamin C)[
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
but also improves the immune function in fighting against the forming of free radicals(1034) and foreign invasion(1035) but also increases the blood flow to the reproductive organ(1036)(1037)(1038) through reducing oxidant stress, increasing NO bioavailability(1037) of which may reduce risk sexual libido(1038) and enhance the chance of conception(1039)(1040)(1041).
Side effects
1. Risk of anaphylactic reaction to patients with a history of allergy to salicylates(1042).
2. Over dose of white willow may cause digestive disorder such as nausea and stomachache(1044)
3. Do not use the herb(1043)
a. If you are aspirin allergy/sensitivity,
b. If you are taking anticoagulants or "blood thinners," and
c. On children with flu-like symptoms or Reye's syndrome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1009) In vitro anti-proliferative effects of the willow bark extract STW 33-I by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1010) Willow leaves' extracts contain anti-tumor agents effective against three cell types by El-Shemy HA1, Aboul-Enein AM, Aboul-Enein KM, Fujita K.(PubMed)
(1011) Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract by Khayyal MT1, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D.(PubMed)
(1012) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress by Sharma S1, Sahu D, Das HR, Sharma D.(PubMed)
(1013) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds by Rauha JP1, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P.(PubMed)
(1014) The study of interactions between active compounds of coffee and willow (Salix sp.) bark by water extract. Durak A1, Gawlik-Dziki U1.(PubMed)
(1015) Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans by Ishikado A1, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell TK, Makino T.(PubMed)
(1016) What Your Doctor May Not Tell You About(TM) Getting Pregnant: Boost Your ... By Raymond Chang, Elena Oumano
(1017) antiestrigenic effectsof bee pollen from Cystus incanus and Salix alba as evaluated by the yeast estrogen screen and the micronucleus assay in human lymphocytes by Pinto B1, Caciagli F, Riccio E, Reali D, Sarić A, Balog T, Likić S, Scarpato R.(PubMed)
(1018) Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment by Santen RJ1, Song RX, Zhang Z, Kumar R, Jeng MH, Masamura S, Lawrence J Jr, MacMahon LP, Yue W, Berstein L.(PubMed)
(1019) Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues by Shenker NS1, Flower KJ2, Wilhelm-Benartzi CS3, Dai W4,5, Bell E6, Gore E7, El Bahrawy M8, Weaver G9, Brown R10, Flanagan JM11.(PubMed)
(1020) Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines by Zhang H, Sairam MR.(PubMed)
(1021) Metabolic Balance for Maximum Health 6/06 June 6, 2006 - - + Juvenon Health Journal Vol. 5 No. 6, June 2006
(1022) [Use of organic acids in acne and skin discolorations therapy].[Article in Polish]by Kapuścińska A1, Nowak I1.(PubMed)
(1023) Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients by Bhatia AC, Jimenez F.(PubMed)
(1024) Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI by Hanevik HI1, Friberg M, Bergh A, Haraldsen C, Kahn JA.(PubMed)
(1025) Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss by Giancotti A1, La Torre R, Spagnuolo A, D'Ambrosio V, Cerekja A, Piazze J, Chistolini A.(PubMed)
(1026) Clinical evidence on the efficacy and safety of an antioxidant optimized 1.5% salicylic acid (SA) cream in the treatment of facial acne: an open, baseline-controlled clinical study by Zheng Y1, Wan M, Chen H, Ye C, Zhao Y, Yi J, Xia Y, Lai W.(PubMed)
(1027) Molecular targets of aspirin and cancer prevention by Alfonso L1, Ai G2, Spitale RC3, Bhat GJ2.(PubMed)
(1028) Effects of salicylic acid and putrescine on storability, quality attributes and antioxidant activity of plum cv. 'Santa Rosa' by Davarynejad GH1, Zarei M1, Nasrabadi ME1, Ardakani E1.(PubMed)
(1029) Salicylic acid promotes seed germination under high salinity by modulating antioxidant activity in Arabidopsis by Lee S1, Kim SG, Park CM.(PubMed)
(1030) An in vivo study examining the antiinflammatory effects of chamomile, meadowsweet, and willow bark in a novel functional beverage by Drummond EM1, Harbourne N, Marete E, Jacquier JC, O'Riordan D, Gibney ER.(PubMed)
(1031) Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark by Drummond EM1, Harbourne N, Marete E, Martyn D, Jacquier J, O'Riordan D, Gibney ER.(PubMed)
(1032) Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells by Hostanska K1, Jürgenliemk G, Abel G, Nahrstedt A, Saller R.(PubMed)
(1033) In vitro anti-proliferative effects of the willow bark extract STW 33-I. by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1034) Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship by Kim DO1, Lee CY.(PubMed)
(1035) Structure, mechanism and regulation of an artificial microbial ecosystem for vitamin C production by Zou W1, Liu L, Chen J.(PubMed)
(1036) Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms by Thakor AS1, Herrera EA, Serón-Ferré M, Giussani DA.(PubMed)
(1037) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(1038) Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride by Yousef MI1.(PubMed)
(1039) Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats by Ashamu E1, Salawu E, Oyewo O, Alhassan A, Alamu O, Adegoke A.(PubMed)
(1040) Vitamin C--the primate fertility factor? by Millar J1.(PubMed)
(1041) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels by Tagler D1, Makanji Y, Tu T, Bernabé BP, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD.(PubMed)
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Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: White willow
White willow is also known as salix alba in herbal medicine, native to Europe and western and central Asia, used in traditional medicine as pain reliever(1007)(1008), anticancer(1009)(1010), antimicrobial(1013), antioxidant(1014)(1015), anti-inflammatory(1011)(1012) and fertility enhancing herb(1016).
1, Antiestrigenic effects
White willow processes antiestrigenic effects(1017) by blocking proliferation in hypersensitive cells (1018) which cause estrogenic diseases, including breast cancer(1019) and metabolism imbalance(1020) diseases, such as obesity and diabetes(1021).
2. Salicylic acid
Salicylic acid, a chemical compound converted from salincin found abundantly in white willow has shown to process anti acne(1022)(1023) one of many symptoms of PCOs) effects, probably through its antioxidant activity(1026) in blocking elevated production of sebum by hyperactive sebaceous glands and blockage of the follicle(1022). According to Telemark Hospital, the acid may also be beneficiary for increased the clinical pregnancy rate when used conjunction with vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI)(1024) and protective against fetal losses(1025), through its anti antithrombotic property(1025). The synthetic version of salicylic acid has also shown to consisting aspirin's cardioprotective effects through its antithrombotic and anti-inflammatory actions(1027).
3. Immune system
The antioxidant(1028)(1029) and anti inflammatory(1030)(1031) effects of white willow enhance immune system fighting against microbial invasion and guarding our body DNA integrity(1033) against irregular cell growth(1032)(1033) through inhibiting the effect of intermediate enzymes and other mechanisms(1027)
d. Vitamin C
Natural vitamin polypeptide C white willow found in white willow not only is found to consist the weight loss property(See the weight loss vitamin C)[
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
but also improves the immune function in fighting against the forming of free radicals(1034) and foreign invasion(1035) but also increases the blood flow to the reproductive organ(1036)(1037)(1038) through reducing oxidant stress, increasing NO bioavailability(1037) of which may reduce risk sexual libido(1038) and enhance the chance of conception(1039)(1040)(1041).
Side effects
1. Risk of anaphylactic reaction to patients with a history of allergy to salicylates(1042).
2. Over dose of white willow may cause digestive disorder such as nausea and stomachache(1044)
3. Do not use the herb(1043)
a. If you are aspirin allergy/sensitivity,
b. If you are taking anticoagulants or "blood thinners," and
c. On children with flu-like symptoms or Reye's syndrome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1009) In vitro anti-proliferative effects of the willow bark extract STW 33-I by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1010) Willow leaves' extracts contain anti-tumor agents effective against three cell types by El-Shemy HA1, Aboul-Enein AM, Aboul-Enein KM, Fujita K.(PubMed)
(1011) Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract by Khayyal MT1, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D.(PubMed)
(1012) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress by Sharma S1, Sahu D, Das HR, Sharma D.(PubMed)
(1013) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds by Rauha JP1, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P.(PubMed)
(1014) The study of interactions between active compounds of coffee and willow (Salix sp.) bark by water extract. Durak A1, Gawlik-Dziki U1.(PubMed)
(1015) Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans by Ishikado A1, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell TK, Makino T.(PubMed)
(1016) What Your Doctor May Not Tell You About(TM) Getting Pregnant: Boost Your ... By Raymond Chang, Elena Oumano
(1017) antiestrigenic effectsof bee pollen from Cystus incanus and Salix alba as evaluated by the yeast estrogen screen and the micronucleus assay in human lymphocytes by Pinto B1, Caciagli F, Riccio E, Reali D, Sarić A, Balog T, Likić S, Scarpato R.(PubMed)
(1018) Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment by Santen RJ1, Song RX, Zhang Z, Kumar R, Jeng MH, Masamura S, Lawrence J Jr, MacMahon LP, Yue W, Berstein L.(PubMed)
(1019) Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues by Shenker NS1, Flower KJ2, Wilhelm-Benartzi CS3, Dai W4,5, Bell E6, Gore E7, El Bahrawy M8, Weaver G9, Brown R10, Flanagan JM11.(PubMed)
(1020) Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines by Zhang H, Sairam MR.(PubMed)
(1021) Metabolic Balance for Maximum Health 6/06 June 6, 2006 - - + Juvenon Health Journal Vol. 5 No. 6, June 2006
(1022) [Use of organic acids in acne and skin discolorations therapy].[Article in Polish]by Kapuścińska A1, Nowak I1.(PubMed)
(1023) Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients by Bhatia AC, Jimenez F.(PubMed)
(1024) Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI by Hanevik HI1, Friberg M, Bergh A, Haraldsen C, Kahn JA.(PubMed)
(1025) Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss by Giancotti A1, La Torre R, Spagnuolo A, D'Ambrosio V, Cerekja A, Piazze J, Chistolini A.(PubMed)
(1026) Clinical evidence on the efficacy and safety of an antioxidant optimized 1.5% salicylic acid (SA) cream in the treatment of facial acne: an open, baseline-controlled clinical study by Zheng Y1, Wan M, Chen H, Ye C, Zhao Y, Yi J, Xia Y, Lai W.(PubMed)
(1027) Molecular targets of aspirin and cancer prevention by Alfonso L1, Ai G2, Spitale RC3, Bhat GJ2.(PubMed)
(1028) Effects of salicylic acid and putrescine on storability, quality attributes and antioxidant activity of plum cv. 'Santa Rosa' by Davarynejad GH1, Zarei M1, Nasrabadi ME1, Ardakani E1.(PubMed)
(1029) Salicylic acid promotes seed germination under high salinity by modulating antioxidant activity in Arabidopsis by Lee S1, Kim SG, Park CM.(PubMed)
(1030) An in vivo study examining the antiinflammatory effects of chamomile, meadowsweet, and willow bark in a novel functional beverage by Drummond EM1, Harbourne N, Marete E, Jacquier JC, O'Riordan D, Gibney ER.(PubMed)
(1031) Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark by Drummond EM1, Harbourne N, Marete E, Martyn D, Jacquier J, O'Riordan D, Gibney ER.(PubMed)
(1032) Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells by Hostanska K1, Jürgenliemk G, Abel G, Nahrstedt A, Saller R.(PubMed)
(1033) In vitro anti-proliferative effects of the willow bark extract STW 33-I. by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1034) Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship by Kim DO1, Lee CY.(PubMed)
(1035) Structure, mechanism and regulation of an artificial microbial ecosystem for vitamin C production by Zou W1, Liu L, Chen J.(PubMed)
(1036) Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms by Thakor AS1, Herrera EA, Serón-Ferré M, Giussani DA.(PubMed)
(1037) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(1038) Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride by Yousef MI1.(PubMed)
(1039) Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats by Ashamu E1, Salawu E, Oyewo O, Alhassan A, Alamu O, Adegoke A.(PubMed)
(1040) Vitamin C--the primate fertility factor? by Millar J1.(PubMed)
(1041) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels by Tagler D1, Makanji Y, Tu T, Bernabé BP, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD.(PubMed)
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