Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research
papers have been written and published on line, including world wide
health, ezine articles, article base, healthblogs, selfgrowth, best
before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
Holiday collection by ATCO blue fame collection
1 cup (250ml) pitted kalamata olives
1 tbsp. (15ml) drained capers
1 clove garlic, crushed
1/4 tsp. (1ml) herbes de Povence ot thyme, crumbled
1/8 tsp. (.05ml) freshly ground pepper
4 oz. (125ml) cream cheese, softened
Place olives capers, garlic, herbes de provence and pepper in food
processor. process using an on/off motion. until mixture is finely
chopped. Place cream cheese in a bowl. Add olive mixture and stir to
combine. transfer to a serving dish. Cover and refrigerate for at least 1
hour or u-p to 2 days. Serve with baguette slices. Make 11/3 cups
(325ml)
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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Saturday, 4 April 2015
Friday, 3 April 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Effectiveness of Vitamins
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
The Vitamins
1. Vitamin B2
Vitamin B2 required for a wide variety of cellular processes, plays a key role in energy metabolism, enhances the digestive system in absorbing nutrients and supports the immune system(285)(286)(287)in fighting against irregular cell growth causes of chronic inflammatory disease(288).
2. Vitamin C
Vitamin C, a water-soluble vitamin and an antioxidant found in high concentrations in immune cells, is not only important in aiding the digestive system in absorbing nutrients, but also enhances the production of white blood cell(289)(290) of the immune system in protection of the body against oxidative stress, harmful bacteria(291) and virus induced inflammation.
3. Vitamin A
Retinoic acid, appears to maintain normal skin health by switching on genes and differentiating keratinocytes (immature skin cells)(292) into mature epidermal cells and helps to detoxify liver(293), and enhances the immune system(294)(295) in protecting our body through its anti tumor functions (296).
4. Vitamin E
Vitamin E is fat-soluble compounds included both tocopherols and tocotrienols. It besides is an polyphenol antioxidants(296)(297)(302) in scavenging free radicals, but also promotes the immune system in enhanced functions of B-cells(298)(299)(300), the immune cells(301)(303) in production of antibodies to destroy irregular cell proliferation.
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatory diseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)
(298) [Toxicology of the synthetic antioxidants BHA and BHT in comparison with the natural antioxidant vitamin E].[Article in German]by Kahl R1, Kappus H.(PubMed)
(299) Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical photoprotectants by Darr D1, Dunston S, Faust H, Pinnell S.(PubMed)
(300) Immune dysfunction and cytokine production in hemodialysis. Could they be lessened by vitamin E-coated dialyzer membrane by Senatore M, Cecere P, Colombo P, Costantini L, Filiberti O, Piccini G, Peona C, Buemi M, Nicoletti A, Rizzuto G.(PubMed)
(301) Prospective crossover trial of the influence of vitamin E-coated dialyzer membranes on T-cell activation and cytokine induction by Girndt M1, Lengler S, Kaul H, Sester U, Sester M, Köhler H.(PubMed)
(302) Vitamin E and immunity by Moriguchi S1, Muraga M.(PubMed)
(303) The role of vitamin E in T-cell differentiation and the decrease of cellular immunity with aging.by Moriguchi S1.(PubMed)
(304) Evaluation of Relation between Anthropometric Indices and Vitamin D Concentrations in Women with Polycystic Ovarian Syndrome by Faraji R1, Sharami SH1, Zahiri Z1, Asgharni M1, Kazemnejad E1, Sadeghi S1.(PubMed)
(305) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
The Vitamins
1. Vitamin B2
Vitamin B2 required for a wide variety of cellular processes, plays a key role in energy metabolism, enhances the digestive system in absorbing nutrients and supports the immune system(285)(286)(287)in fighting against irregular cell growth causes of chronic inflammatory disease(288).
2. Vitamin C
Vitamin C, a water-soluble vitamin and an antioxidant found in high concentrations in immune cells, is not only important in aiding the digestive system in absorbing nutrients, but also enhances the production of white blood cell(289)(290) of the immune system in protection of the body against oxidative stress, harmful bacteria(291) and virus induced inflammation.
3. Vitamin A
Retinoic acid, appears to maintain normal skin health by switching on genes and differentiating keratinocytes (immature skin cells)(292) into mature epidermal cells and helps to detoxify liver(293), and enhances the immune system(294)(295) in protecting our body through its anti tumor functions (296).
4. Vitamin E
Vitamin E is fat-soluble compounds included both tocopherols and tocotrienols. It besides is an polyphenol antioxidants(296)(297)(302) in scavenging free radicals, but also promotes the immune system in enhanced functions of B-cells(298)(299)(300), the immune cells(301)(303) in production of antibodies to destroy irregular cell proliferation.
5. Vitamin D
15
minutes in the the Sun daily has shown to provide necessary vitamin D
for the body. Over 68% of women with PCOs had vitamin D
deficiency.(304). According to Medical faculty of P.J.Šafarik University
Košice, women with vitamin D deficient PCOs are exhibited a
significantly higher body mass index (BMI), fasting insulin, and
homeostasis model assessment-insulin resistance and borderline higher
glycemia in comparison to controls(305).Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatory diseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)
(286) Edible mushrooms: improving human health and promoting quality life by Valverde ME1, Hernández-Pérez T1, Paredes-López O1.(PubMed)
(292) Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C by Schoultz I1, McKay CM, Graepel R, Phan VC, Wang A, Söderholm J, McKay DM.(PubMed)
(287) [Effect of some vitamins on activity of immunocompetent cells].[Article in Russian]by Nezgovorov DV.(PubMed)
(288)
Antioxidants keep the potentially probiotic but highly oxygen-sensitive
human gut bacterium Faecalibacterium prausnitzii alive at ambient air
by Khan MT1, van Dijl JM1, Harmsen HJ1.(PubMed)
(289) Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview by Pallotta V1, Gevi F1, D'alessandro A1, Zolla L1.(PubMed)
(290) Red blood cell metabolism under prolonged anaerobic storage by D'Alessandro A1, Gevi F, Zolla L.(PubMed)
(291) Alterations in antioxidant defense system of workers chronically exposed to arsenic, cadmium and mercury from coal flying ash by Zeneli L1, Sekovanić A, Ajvazi M, Kurti L, Daci N.(PubMed)
(293) Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytes by Meves A1, Stock SN, Beyerle A, Pittelkow MR, Peus D.(PubMed)
(297) Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes by Klassert TE1, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H.(PubMed)
(294). Effects of dried fish on antioxidant levels in rat liver by Anilakumar KR1, Khanum F, Krishna KR, Viswanathan KR.(PubMed)
(298) [Toxicology of the synthetic antioxidants BHA and BHT in comparison with the natural antioxidant vitamin E].[Article in German]by Kahl R1, Kappus H.(PubMed)
(299) Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical photoprotectants by Darr D1, Dunston S, Faust H, Pinnell S.(PubMed)
(300) Immune dysfunction and cytokine production in hemodialysis. Could they be lessened by vitamin E-coated dialyzer membrane by Senatore M, Cecere P, Colombo P, Costantini L, Filiberti O, Piccini G, Peona C, Buemi M, Nicoletti A, Rizzuto G.(PubMed)
(301) Prospective crossover trial of the influence of vitamin E-coated dialyzer membranes on T-cell activation and cytokine induction by Girndt M1, Lengler S, Kaul H, Sester U, Sester M, Köhler H.(PubMed)
(302) Vitamin E and immunity by Moriguchi S1, Muraga M.(PubMed)
(303) The role of vitamin E in T-cell differentiation and the decrease of cellular immunity with aging.by Moriguchi S1.(PubMed)
(304) Evaluation of Relation between Anthropometric Indices and Vitamin D Concentrations in Women with Polycystic Ovarian Syndrome by Faraji R1, Sharami SH1, Zahiri Z1, Asgharni M1, Kazemnejad E1, Sadeghi S1.(PubMed)
(305) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
Smoke Paprika and lime Aioli
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Holiday collection by ATCO blue fame collection
Serve this aioli as a dip for shrimp or as a sauce for shrimp cocktail
1 cup (250ml) mayonnaise
1 tbsp. (15ml) fresh lime juice
1 tsp. (5ml) grated lime peel
1 tsp. (5ml) smoke paprika
1/4 tsp. (1ml) salt
2 cloves garlic, crushed
Combined all ingredients until blenched. Transfer to a serving dish. Cover and refrigerate for at least 2 hours or up to 24 hours. Makes about I cup (250m)
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Holiday collection by ATCO blue fame collection
Serve this aioli as a dip for shrimp or as a sauce for shrimp cocktail
1 cup (250ml) mayonnaise
1 tbsp. (15ml) fresh lime juice
1 tsp. (5ml) grated lime peel
1 tsp. (5ml) smoke paprika
1/4 tsp. (1ml) salt
2 cloves garlic, crushed
Combined all ingredients until blenched. Transfer to a serving dish. Cover and refrigerate for at least 2 hours or up to 24 hours. Makes about I cup (250m)
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Thursday, 2 April 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The General approaches to Prevent the Unpreventable?
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
The General Approaches to prevent the unpreventable?
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
1. Healthy lifestyle(256)(257)(258)
According to Shahid Beheshti University of Medical Sciences, women with unhealthy life style are associated to increased risk of chronic diseases(260), including PCOs in comparison to those of healthy women(259), probably due to nutrient deficiency effects of immune functioning(261).
2. Balanced diet
Epidemiological data suggest that dietary patterns strongly affect inflammatory processes(265).
Balancing diet(257)(258) with high in veggies and fruits(257) and less in meats not only provides sufficient nutrients to your body but also enhances the immunity in fighting against inflammatory diseases(264), including PCOs(264), irregular cell growth(263) and oxidative stress(262). Reduced intake of trans and saturated fats and increased intake of omega-3 and omega-9 fatty acids(257) and eating anti-inflammatory foods (fiber(272)(273), omega-3 fatty acids(269), vitamin E(270), and red wine(271) should also be emphasized(255)(265).
3. Moderate exercise(257)
Moderate exercise not only increases blood flow to strengthen the body tissues(274)(275) and organs(276), including the reproductive system but also enhances the immunity(277) in fighting against inflammatory process(277)(278) due to irregular cell growth(281)(282) and foreign invasion(279)(280).
4. Yoga
Yoga is a physical, mental, and spiritual practice in Hinduism, Buddhism.
According to studies holistic yoga therapy showed a significant effects in reducing anti-müllerian hormone (AMH-primary outcome), luteinizing hormone (LH), testosterone, hirsutism, and improving menstrual frequency, glucose, lipid, and insulin values(284) with nonsignificant changes in body weight, FSH, and prolactin in adolescent PCOS(283).
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(260) The Science of Stress, Bad Habits, and Risk of Chronic Diseases
(261) The risks of poor nutrition(SA health)
(262) Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis by Murri M1, Luque-Ramírez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF.(PubMed)
(263) The reproductive phenotype in polycystic ovary syndrome by Chang RJ1.(PubMed)
(264) Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential by Piltonen TT1, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC.(PubMed)
(265) Anti-inflammatory effects of plant-based foods and of their constituents by Watzl B1.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatory diseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(269) Dietary n-6 and n-3 fatty acids in immunity and autoimmune disease by Harbige LS1.(PubMed)
(270) Effect of conjugated linoleic Acid, vitamin e, alone or combined on immunity and inflammatory parameters in adults with active rheumatoid arthritis: a randomized controlled trial by Aryaeian N1, Djalali M2, Shahram F3, Djazayery A4, Eshragian MR5.(PubMed)
(271) Red wine may be used in the therapy of myocarditis by Chen CJ1, Yu W, Wang W.(PubMed)
(272) High dietary fiber lowers systemic inflammation: potential utility in COPD and lung cancer by Young RP1, Hopkins RJ2.(PubMed)
(273) Dietary fibre linked to decreased inflammation in overweight minority youth by Miller SJ1, Batra AK, Shearrer GE, House BT, Cook LT, Pont SJ, Goran MI, Davis JN.(PubMed)
(274) Effects of high-intensity blood flow restriction exercise on muscle fatigue by Neto GR1, Santos HH2, Sousa JB3, Júnior AT4,(PubMed)
(275) Influence of Blood Flow Restriction During Low-intensity Resistance Exercise on the Post-exercise Hypotensive Response by Maior AS1, Simão R, Rocha Martins MS, Freitas de Salles B, Willardson JM. Araújo JP3, Aniceto RR5, Sousa MS3.(PubMed)
(276) Impact of exercise on muscle and nonmuscle organs by Boström PA1, Graham EL, Georgiadi A, Ma X.(PubMed)
(277) Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation by Benatti FB1, Pedersen BK2.(PubMed)
(278) The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases by Brandt C1, Pedersen BK.(PubMed)
(279) Enhanced follicular dendritic cell-B cell interaction in HIV and SIV infections and its potential role in polyclonal B cell activation by Rosenberg YJ1, Lewis MG, Kosco-Vilbois MH.(PubMed)
(280) THE FATE OF THE GIANT CELLS IN HEALING TUBERCULOUS TISSUE, AS OBSERVED IN A CASE OF HEALING TUBERCULOUS MENINGITIS by Hektoen L1.(PubMed)
(281) Cell-mediated immunity to mouse tumors: some recent findings. Hellström KE, Hellström I.(PubMed)
(282) Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors by Ngiow SF1, von Scheidt B, Akiba H, Yagita H, Teng MW, Smyth MJ.(PubMed)
(283) Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome: a randomized controlled trial by Nidhi R1, Padmalatha V, Nagarathna R, Amritanshu R.(PubMed)
(284) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome byNidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
The General Approaches to prevent the unpreventable?
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
1. Healthy lifestyle(256)(257)(258)
According to Shahid Beheshti University of Medical Sciences, women with unhealthy life style are associated to increased risk of chronic diseases(260), including PCOs in comparison to those of healthy women(259), probably due to nutrient deficiency effects of immune functioning(261).
2. Balanced diet
Epidemiological data suggest that dietary patterns strongly affect inflammatory processes(265).
Balancing diet(257)(258) with high in veggies and fruits(257) and less in meats not only provides sufficient nutrients to your body but also enhances the immunity in fighting against inflammatory diseases(264), including PCOs(264), irregular cell growth(263) and oxidative stress(262). Reduced intake of trans and saturated fats and increased intake of omega-3 and omega-9 fatty acids(257) and eating anti-inflammatory foods (fiber(272)(273), omega-3 fatty acids(269), vitamin E(270), and red wine(271) should also be emphasized(255)(265).
3. Moderate exercise(257)
Moderate exercise not only increases blood flow to strengthen the body tissues(274)(275) and organs(276), including the reproductive system but also enhances the immunity(277) in fighting against inflammatory process(277)(278) due to irregular cell growth(281)(282) and foreign invasion(279)(280).
4. Yoga
Yoga is a physical, mental, and spiritual practice in Hinduism, Buddhism.
According to studies holistic yoga therapy showed a significant effects in reducing anti-müllerian hormone (AMH-primary outcome), luteinizing hormone (LH), testosterone, hirsutism, and improving menstrual frequency, glucose, lipid, and insulin values(284) with nonsignificant changes in body weight, FSH, and prolactin in adolescent PCOS(283).
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(260) The Science of Stress, Bad Habits, and Risk of Chronic Diseases
(261) The risks of poor nutrition(SA health)
(262) Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis by Murri M1, Luque-Ramírez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF.(PubMed)
(263) The reproductive phenotype in polycystic ovary syndrome by Chang RJ1.(PubMed)
(264) Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential by Piltonen TT1, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC.(PubMed)
(265) Anti-inflammatory effects of plant-based foods and of their constituents by Watzl B1.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatory diseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(269) Dietary n-6 and n-3 fatty acids in immunity and autoimmune disease by Harbige LS1.(PubMed)
(270) Effect of conjugated linoleic Acid, vitamin e, alone or combined on immunity and inflammatory parameters in adults with active rheumatoid arthritis: a randomized controlled trial by Aryaeian N1, Djalali M2, Shahram F3, Djazayery A4, Eshragian MR5.(PubMed)
(271) Red wine may be used in the therapy of myocarditis by Chen CJ1, Yu W, Wang W.(PubMed)
(272) High dietary fiber lowers systemic inflammation: potential utility in COPD and lung cancer by Young RP1, Hopkins RJ2.(PubMed)
(273) Dietary fibre linked to decreased inflammation in overweight minority youth by Miller SJ1, Batra AK, Shearrer GE, House BT, Cook LT, Pont SJ, Goran MI, Davis JN.(PubMed)
(274) Effects of high-intensity blood flow restriction exercise on muscle fatigue by Neto GR1, Santos HH2, Sousa JB3, Júnior AT4,(PubMed)
(275) Influence of Blood Flow Restriction During Low-intensity Resistance Exercise on the Post-exercise Hypotensive Response by Maior AS1, Simão R, Rocha Martins MS, Freitas de Salles B, Willardson JM. Araújo JP3, Aniceto RR5, Sousa MS3.(PubMed)
(276) Impact of exercise on muscle and nonmuscle organs by Boström PA1, Graham EL, Georgiadi A, Ma X.(PubMed)
(277) Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation by Benatti FB1, Pedersen BK2.(PubMed)
(278) The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases by Brandt C1, Pedersen BK.(PubMed)
(279) Enhanced follicular dendritic cell-B cell interaction in HIV and SIV infections and its potential role in polyclonal B cell activation by Rosenberg YJ1, Lewis MG, Kosco-Vilbois MH.(PubMed)
(280) THE FATE OF THE GIANT CELLS IN HEALING TUBERCULOUS TISSUE, AS OBSERVED IN A CASE OF HEALING TUBERCULOUS MENINGITIS by Hektoen L1.(PubMed)
(281) Cell-mediated immunity to mouse tumors: some recent findings. Hellström KE, Hellström I.(PubMed)
(282) Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors by Ngiow SF1, von Scheidt B, Akiba H, Yagita H, Teng MW, Smyth MJ.(PubMed)
(283) Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome: a randomized controlled trial by Nidhi R1, Padmalatha V, Nagarathna R, Amritanshu R.(PubMed)
(284) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome byNidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)
Layered shrimp and salsa dip
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Holiday collection by ATCO blue fame collection
8 oz. (250ml) cream cheese, softened
1/8 tsp. (.05ml) garlic powder
1/8 tsp. (.05ml) hot pepper sauce
1 cup (250ml) medium salsa
2 tbsp. (25ml) chopped fresh cilantro
11/2 cup (375ml) coarsely chopped cooked shrimp
2 tbsp. (25ml) thinly sliced green onion
Using medium speed of an electric mixer, beat together cream cheese garlic powder and hot pepper sauce until blended. Spread cream cheese mixture over bottom of a shallow 6 inch (15cm) serving dish. Combine salsa and cilantro. Spoon over cream cheese mixture. Sprinkle shrimp over salsa mixture. Top with green onion. Serve with crackers or tortilla chips. Serve 6 - 8.
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Holiday collection by ATCO blue fame collection
8 oz. (250ml) cream cheese, softened
1/8 tsp. (.05ml) garlic powder
1/8 tsp. (.05ml) hot pepper sauce
1 cup (250ml) medium salsa
2 tbsp. (25ml) chopped fresh cilantro
11/2 cup (375ml) coarsely chopped cooked shrimp
2 tbsp. (25ml) thinly sliced green onion
Using medium speed of an electric mixer, beat together cream cheese garlic powder and hot pepper sauce until blended. Spread cream cheese mixture over bottom of a shallow 6 inch (15cm) serving dish. Combine salsa and cilantro. Spoon over cream cheese mixture. Sprinkle shrimp over salsa mixture. Top with green onion. Serve with crackers or tortilla chips. Serve 6 - 8.
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Wednesday, 1 April 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Complications (Revised edition with Citations)
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
PCOs Complications
1. Cardiovascular diseases
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. Women with PCOs have found to have increased risk of CVD due to hyperandrogenism in aggravation of abdominal obesity(211), insulin resistance forming(211), metabolic syndrome(212), type 2 diabetes(212)(213), altered plasma lipid profile(215), sympathovagal imbalance(216),.... According to University of Western Australia, treatment in uncorrelated components, such as insulin resistance, dyslipidaemia/hypertension or hyperandrogenaemia may be effectively to reduce differing cardiometabolic outcomes(214). Non-medical (normalization of weight, healthy lifestyle) and medical (metformin, thiazolidinediones, spironolactone, and statins) interventions were found effectively in reduced long-term risk for cardiovascular morbidity and mortality in women with PCOs(217).
Conflictingly, according to the study by Division of General Internal Medicine, Mayo Clinic, although women with PCOS weighed more than controls, there was no increased prevalence of other CV risk factors(218). The study also insisted that data on the incidence of CV events are lacking in PCOs' population(218)
2. Stroke
Besides cancer and heart diseases, stroke is the third leading cause of death. Approximate 1/4 of all stroke victims die as a direct result of the stroke or it's complications. Epidemiological evidences suggested that women with PCOs are at increased risk of stroke(220)(221). According to the review of 1340 articles, 5 follow-up studies published between 2000 and 2008 conducted by Leiden University Medical Center,, risk of stroke of women with PCOs was 2 folds higher in comparison of women with PCOS to women without PCOS(219).
3. Endometrial cancer
Endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
women with polycystic ovary syndrome (PCOS) with altered estrogen and/or abnormality of levels progesterone (P4) at gene level(222), mutation gene(223)(227), abnormal levels of hormone (gonadotropins, estrogens, androgens, prolactin, andserotonin and progesterone),(228), hyperandrogenism(224), abnormal menstrual pattern(225), insulin resistance(228) associated with PCOS and obesity(226)(228), may contribute to increased endometrial cancer risk(222). Metformin(229) and combination of metformax, bromcriptine mesylate and metformin showed to improve clinical and metabolic syndrome in women with PCOS(230) with metformin alone through up-regulated tumor suppressor gene such as p53, cyclin D2 and BCL-2)(229).
4. Dyslipidemia
Dyslipidemia, one of metabolic syndrome has found to be associated to many patients with polycystic ovary syndrome (PCOS) risk factor(233), chracterized by elevated low-density lipoprotein (LDL), triglyceride levels and decreased high-density lipoprotein (HDL)(234), probably different metabolic aetiologies depending on DHEA-S metabolism, independent to insulin concentrations(235).
According to University of Brescia, Italy, use of the oral contraceptive for suppressed gonadotropin and androgen values and increased the levels of sex hormone binding globulin in women with PCOs showed a significant increase in triglycerides, high density lipoprotein (HDL) cholesterol system(232). Phytochemicals Berberine and monacolin showed effectively in a balanced lipid profile, through improve lipid metabolism in oral contraceptive induced hypercholesterolemia in women with or without PCOS(231).
5. Pregnancy risk
Women with PCOs are associated to higher rate of early pregnancy loss in comparison to women with reproductive problems(237). According to joint study conducted by Norwegian University of Science and St Olavs Hospital, wone with PCOs are associated to pre term delivery in twin pregnancies(236). Treatment with N-acetylcysteine (NAC) showed to enhance higher odds of getting pregnant with a live birth(238). In subfertile women with anovulatory PCOS, letrozole improved live birth and pregnancy rates in comparison to clomiphene citrate(239).
Adding phytochemical Cimicifugae Racemosae to clomiphene-induction cycles with timed intercourse significantly improved cycle outcomes and pregnancy rates in women with polycystic ovarian(241). Traditional Chinese formula, Danzhi Xiaoyao Pill (DXP) effectively enhanced the ovulation rate and the clinical pregnancy rate of 60% in anovulation infertility patients with PCOS complicated IR(242).
Dr. Ried K. at National Institute of Integrative Medicine, Hawthorn, Melbourne, VIC, Australia said " Chinese herbal medicine can improve pregnancy rates 2-fold within a 3-6 month period compared with Western medical fertility drug therapy, including women with PCOS"(240).
6. Infertility(See diseases associated to PCOs)
7. Higher risk of Gestational diabetes
Epidemiologocal studies, linking higher incidence of gestational diabetes mellitus (GDM) for women with PCOs has porduced inconsistent result(243)(244). Aristotle University suggested a improve properly designed studies are necessary before any recommendation to pregnant women with PCOS in regard to the risk of GDM(245), But according to Imperial College School of Medicine, there is a higher prevalence of polycystic ovarian morphology in women with a history of gestational diabetes(246).
8. Depression
Women with PCOS are found to have a higher rate of depression in comparison group women without(247)(248)(250). Psychologically, according to Institute of Psychology, Eötvös Loránd University, women with PCOs are associated with a great number of psychological symptoms, including (e.g. depression, anxiety, body image dissatisfaction, eating and sexual disorders, and low life satisfaction) due to gynaecological disorder of endocrine origin(249).
9. Liver diseases
Women with PCOS are associated to high risk of NAFLD(251)(252)(253). The suggested that some women with PCOS particularly those with an evidence of metabolic syndrome. should be considered to be screened for liver disease at an earlier age(254).
10. Diabetes(See diseases associated to PCOs)
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(211) Cardiovascular risk factors and events in women with androgen excess by Macut D1, Antić IB, Bjekić-Macut J.(PubMed)
(212) Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society by Wild RA1, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, Lobo R, Norman RJ, Talbott E, Dumesic DA.(PubMed)
(213) Type 2 diabetes and cardiovascular disease in polycystic ovary syndrome: what are the risks and can they be reduced? by Tomlinson J1, Millward A, Stenhouse E, Pinkney J.(PubMed)
(214) Clustering of metabolic and cardiovascular risk factors in the polycystic ovary syndrome: a principal component analysis by Stuckey BG1, Opie N2, Cussons AJ3, Watts GF4, Burke V4.(PubMed)
(215) Cardiac fatty acid uptake and metabolism in the rat model of polycystic ovary syndrome by Tepavčević S1, Milutinović DV, Macut D, Stojiljković M, Nikolić M, Božić-Antić I, Ćulafić T, Bjekić-Macut J, Matić G, Korićanac G.(PubMed)
(216) Assessment of cardiovascular autonomic function in patients with polycystic ovary syndrome by Saranya K1, Pal GK, Habeebullah S, Pal P.(PubMed)
(217) Cardiovascular risk and subclinical cardiovascular disease in polycystic ovary syndrome by Bajuk Studen K1, Jensterle Sever M, Pfeifer M.(PubMed)
(218) Risk of cardiovascular events in patients with polycystic ovary syndrome by Iftikhar S1, Collazo-Clavell ML, Roger VL, St Sauver J, Brown RD Jr, Cha S, Rhodes DJ.(PubMed)
(220) Risk of coronary heart disease and risk of stroke in women with polycystic ovary syndrome: a systematic review and meta-analysis by Anderson SA1, Barry JA1, Hardiman PJ2(PubMed)
(221) Cardiovascular disease and risk factors in PCOS women of postmenopausal age: a 21-year controlled follow-up study by Schmidt J1, Landin-Wilhelmsen K, Brännström M, Dahlgren E.(PubMed)
(22) Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro by Piltonen TT1, Chen JC2, Khatun M3, Kangasniemi M3, Liakka A4, Spitzer T2, Tran N2, Huddleston H2, Irwin JC2, Giudice LC5.(PubMed)
(223) The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome - a proof-of-concept study by Shafiee MN1, Malik DA, Yunos RI, Atiomo W, Omar MH, Ghani NA, Hatta AZ, Seedhouse C, Chapman C, Mokhtar NM.(PubMed)
(224) Micronized estradiol and progesterone therapy in primary, preinvasive endometrial cancer (1A/G1) in young women with polycystic ovarian syndrome by Stanosz S1, von Mach-Szczypiński J, Sieja K, Koœciuszkiewicz J.(PubMed)
(225) The percentages of endometrial hyperplasia and endometrial cancer among polycystic ovary syndrome (PCOS) patients presenting with abnormal menstrual pattern by Prakansamut N, Sirayapiwat P, Triratanachat S.(PubMed)
(226) PCOS and obesity: insulin resistance might be a common etiology for the development of type I endometrial carcinoma by Li X1, Shao R2(PubMed)
(227) Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential by Piltonen TT1, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC.(PubMed)
(229) The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome - a proof-of-concept study by Shafiee MN1, Malik DA, Yunos RI, Atiomo W, Omar MH, Ghani NA, Hatta AZ, Seedhouse C, Chapman C, Mokhtar NM.(PubMed)
(230) Micronized estradiol and progesterone therapy in primary, preinvasive endometrial cancer (1A/G1) in young women with polycystic ovarian syndrome by Stanosz S1, von Mach-Szczypiński J, Sieja K, Koœciuszkiewicz J.(PubMed)
(231) Berberine and monacolin effects on the cardiovascular risk profile of women with oestroprogestin-induced hypercholesterolemia by Cicero AF1, Reggi A, Parini A, Morbini M, Rosticci M, Grandi E, Borghi C.(PubMed)
(232) Effects of long-term administration of an oral contraceptive containing ethinylestradiol and cyproterone acetate on lipid metabolism in women with polycystic ovary syndrome by Falsetti L1, Pasinetti E.(PubMed)
(233) Polycystic Ovary Syndrome and the Metabolic Syndrome by Julie L. Sharpless, MD(American diabeyes association)
(234) Pathophysiology and types of dyslipidemia in PCOS by Diamanti-Kandarakis E1, Papavassiliou AG, Kandarakis SA, Chrousos GP(PubMed)
(235) Dyslipidaemia in polycystic ovarian syndrome: different groups, different aetiologies? by Meirow D1, Raz I, Yossepowitch O, Brzezinski A, Rosler A, Schenker JG, Berry EM.(PubMed)
(236) Pregnancy and perinatal outcomes in women with polycystic ovary syndrome and twin births: a population-based cohort study by Løvvik TS1, Wikström AK, Neovius M, Stephansson O, Roos N, Vanky E.(PubMed)
(237) [Reproductive problems in women with PCOS, the impact of PAI-1 carriers of 4G PAI-1 polymorphism and BMI]. [Article in Russian] [No authors listed](PubMed)
(238) N-acetylcysteine for polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled clinical trials byThakker D1, Raval A2, Patel I3, Walia R4.(PubMed)
(239) Aromatase inhibitors for subfertile women with polycystic ovary syndrome by Franik S1, Kremer JA, Nelen WL, Farquhar C.(PubMed)
(240) Chinese herbal medicine for female infertility: an updated meta-analysis by Ried K1.(PubMed)
(241) Adding the phytoestrogen Cimicifugae Racemosae to clomiphene induction cycles with timed intercourse in polycystic ovary syndrome improves cycle outcomes and pregnancy rates - a randomized trial by Shahin AY1, Mohammed SA.(PubMed)
(242) [Effect of danzhi xiaoyao pill on ovulation induction of polycystic ovarian syndrome patients of pathogenic fire derived from stagnation of gan-qi]. [Article in Chinese] by Liu Y1, Mao LH.(PubMed)
(243) Prevalence of gestational diabetes mellitus in polycystic ovarian syndrome (PCOS) patients pregnant after ovulation induction with gonadotrophins by Vollenhoven B1, Clark S, Kovacs G, Burger H, Healy D.(PubMed)
(244) Prevalence of gestational diabetes mellitus and pregnancy outcomes in Asian women with polycystic ovary syndrome by Weerakiet S1, Srisombut C, Rojanasakul A, Panburana P, Thakkinstian A, Herabutya Y.(PubMed)
(245)
(246) The prevalence of polycystic ovaries in women with a history of gestational diabetes. Kousta E1, Cela E, Lawrence N, Penny A, Millauer B, White D, Wilson H, Robinson S, Johnston D, McCarthy M, Franks S.(PubMed)
(247) Reporting the rates of depression in polycystic ovary syndrome (PCOS) by Barry JA1, Kuczmierczyk AR, Hardiman PJ.(PubMed)
(248) Depression symptoms and body dissatisfaction association among polycystic ovary syndrome women by Pastore LM1, Patrie JT, Morris WL, Dalal P, Bray MJ.(PubMed)
(249) Psychological aspects of the polycystic ovary syndrome by Farkas J1, Rigó A, Demetrovics Z.(PubMed)
(250) Is having polycystic ovary syndrome a predictor of poor psychological function including anxiety and depression? by Deeks AA1, Gibson-Helm ME, Paul E, Teede HJ.(PubMed)
(251) Are women with polycystic ovarian syndrome at a high risk of non-alcoholic Fatty liver disease; a meta-analysis by Ramezani-Binabaj M1, Motalebi M2, Karimi-Sari H3, Rezaee-Zavareh MS1, Alavian SM4.(PubMed)
(252) Nonalcoholic fatty liver disease in women with polycystic ovary syndrome by Cerda C1, Pérez-Ayuso RM, Riquelme A, Soza A, Villaseca P, Sir-Petermann T, Espinoza M, Pizarro M, Solis N, Miquel JF, Arrese M.(PubMed)
(253) [Prevalence of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome: a case-control study]. [Article in Chinese] by Zheng RH1, Ding CF.(PubMed)
(254) An association between non-alcoholic fatty liver disease and polycystic ovarian syndrome by Brzozowska MM1, Ostapowicz G, Weltman MD(PubMed)
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Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
PCOs Complications
1. Cardiovascular diseases
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. Women with PCOs have found to have increased risk of CVD due to hyperandrogenism in aggravation of abdominal obesity(211), insulin resistance forming(211), metabolic syndrome(212), type 2 diabetes(212)(213), altered plasma lipid profile(215), sympathovagal imbalance(216),.... According to University of Western Australia, treatment in uncorrelated components, such as insulin resistance, dyslipidaemia/hypertension or hyperandrogenaemia may be effectively to reduce differing cardiometabolic outcomes(214). Non-medical (normalization of weight, healthy lifestyle) and medical (metformin, thiazolidinediones, spironolactone, and statins) interventions were found effectively in reduced long-term risk for cardiovascular morbidity and mortality in women with PCOs(217).
Conflictingly, according to the study by Division of General Internal Medicine, Mayo Clinic, although women with PCOS weighed more than controls, there was no increased prevalence of other CV risk factors(218). The study also insisted that data on the incidence of CV events are lacking in PCOs' population(218)
2. Stroke
Besides cancer and heart diseases, stroke is the third leading cause of death. Approximate 1/4 of all stroke victims die as a direct result of the stroke or it's complications. Epidemiological evidences suggested that women with PCOs are at increased risk of stroke(220)(221). According to the review of 1340 articles, 5 follow-up studies published between 2000 and 2008 conducted by Leiden University Medical Center,, risk of stroke of women with PCOs was 2 folds higher in comparison of women with PCOS to women without PCOS(219).
3. Endometrial cancer
Endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
women with polycystic ovary syndrome (PCOS) with altered estrogen and/or abnormality of levels progesterone (P4) at gene level(222), mutation gene(223)(227), abnormal levels of hormone (gonadotropins, estrogens, androgens, prolactin, andserotonin and progesterone),(228), hyperandrogenism(224), abnormal menstrual pattern(225), insulin resistance(228) associated with PCOS and obesity(226)(228), may contribute to increased endometrial cancer risk(222). Metformin(229) and combination of metformax, bromcriptine mesylate and metformin showed to improve clinical and metabolic syndrome in women with PCOS(230) with metformin alone through up-regulated tumor suppressor gene such as p53, cyclin D2 and BCL-2)(229).
4. Dyslipidemia
Dyslipidemia, one of metabolic syndrome has found to be associated to many patients with polycystic ovary syndrome (PCOS) risk factor(233), chracterized by elevated low-density lipoprotein (LDL), triglyceride levels and decreased high-density lipoprotein (HDL)(234), probably different metabolic aetiologies depending on DHEA-S metabolism, independent to insulin concentrations(235).
According to University of Brescia, Italy, use of the oral contraceptive for suppressed gonadotropin and androgen values and increased the levels of sex hormone binding globulin in women with PCOs showed a significant increase in triglycerides, high density lipoprotein (HDL) cholesterol system(232). Phytochemicals Berberine and monacolin showed effectively in a balanced lipid profile, through improve lipid metabolism in oral contraceptive induced hypercholesterolemia in women with or without PCOS(231).
5. Pregnancy risk
Women with PCOs are associated to higher rate of early pregnancy loss in comparison to women with reproductive problems(237). According to joint study conducted by Norwegian University of Science and St Olavs Hospital, wone with PCOs are associated to pre term delivery in twin pregnancies(236). Treatment with N-acetylcysteine (NAC) showed to enhance higher odds of getting pregnant with a live birth(238). In subfertile women with anovulatory PCOS, letrozole improved live birth and pregnancy rates in comparison to clomiphene citrate(239).
Adding phytochemical Cimicifugae Racemosae to clomiphene-induction cycles with timed intercourse significantly improved cycle outcomes and pregnancy rates in women with polycystic ovarian(241). Traditional Chinese formula, Danzhi Xiaoyao Pill (DXP) effectively enhanced the ovulation rate and the clinical pregnancy rate of 60% in anovulation infertility patients with PCOS complicated IR(242).
Dr. Ried K. at National Institute of Integrative Medicine, Hawthorn, Melbourne, VIC, Australia said " Chinese herbal medicine can improve pregnancy rates 2-fold within a 3-6 month period compared with Western medical fertility drug therapy, including women with PCOS"(240).
6. Infertility(See diseases associated to PCOs)
7. Higher risk of Gestational diabetes
Epidemiologocal studies, linking higher incidence of gestational diabetes mellitus (GDM) for women with PCOs has porduced inconsistent result(243)(244). Aristotle University suggested a improve properly designed studies are necessary before any recommendation to pregnant women with PCOS in regard to the risk of GDM(245), But according to Imperial College School of Medicine, there is a higher prevalence of polycystic ovarian morphology in women with a history of gestational diabetes(246).
8. Depression
Women with PCOS are found to have a higher rate of depression in comparison group women without(247)(248)(250). Psychologically, according to Institute of Psychology, Eötvös Loránd University, women with PCOs are associated with a great number of psychological symptoms, including (e.g. depression, anxiety, body image dissatisfaction, eating and sexual disorders, and low life satisfaction) due to gynaecological disorder of endocrine origin(249).
9. Liver diseases
Women with PCOS are associated to high risk of NAFLD(251)(252)(253). The suggested that some women with PCOS particularly those with an evidence of metabolic syndrome. should be considered to be screened for liver disease at an earlier age(254).
10. Diabetes(See diseases associated to PCOs)
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(211) Cardiovascular risk factors and events in women with androgen excess by Macut D1, Antić IB, Bjekić-Macut J.(PubMed)
(212) Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society by Wild RA1, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, Lobo R, Norman RJ, Talbott E, Dumesic DA.(PubMed)
(213) Type 2 diabetes and cardiovascular disease in polycystic ovary syndrome: what are the risks and can they be reduced? by Tomlinson J1, Millward A, Stenhouse E, Pinkney J.(PubMed)
(214) Clustering of metabolic and cardiovascular risk factors in the polycystic ovary syndrome: a principal component analysis by Stuckey BG1, Opie N2, Cussons AJ3, Watts GF4, Burke V4.(PubMed)
(215) Cardiac fatty acid uptake and metabolism in the rat model of polycystic ovary syndrome by Tepavčević S1, Milutinović DV, Macut D, Stojiljković M, Nikolić M, Božić-Antić I, Ćulafić T, Bjekić-Macut J, Matić G, Korićanac G.(PubMed)
(216) Assessment of cardiovascular autonomic function in patients with polycystic ovary syndrome by Saranya K1, Pal GK, Habeebullah S, Pal P.(PubMed)
(217) Cardiovascular risk and subclinical cardiovascular disease in polycystic ovary syndrome by Bajuk Studen K1, Jensterle Sever M, Pfeifer M.(PubMed)
(218) Risk of cardiovascular events in patients with polycystic ovary syndrome by Iftikhar S1, Collazo-Clavell ML, Roger VL, St Sauver J, Brown RD Jr, Cha S, Rhodes DJ.(PubMed)
(220) Risk of coronary heart disease and risk of stroke in women with polycystic ovary syndrome: a systematic review and meta-analysis by Anderson SA1, Barry JA1, Hardiman PJ2(PubMed)
(221) Cardiovascular disease and risk factors in PCOS women of postmenopausal age: a 21-year controlled follow-up study by Schmidt J1, Landin-Wilhelmsen K, Brännström M, Dahlgren E.(PubMed)
(22) Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro by Piltonen TT1, Chen JC2, Khatun M3, Kangasniemi M3, Liakka A4, Spitzer T2, Tran N2, Huddleston H2, Irwin JC2, Giudice LC5.(PubMed)
(223) The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome - a proof-of-concept study by Shafiee MN1, Malik DA, Yunos RI, Atiomo W, Omar MH, Ghani NA, Hatta AZ, Seedhouse C, Chapman C, Mokhtar NM.(PubMed)
(224) Micronized estradiol and progesterone therapy in primary, preinvasive endometrial cancer (1A/G1) in young women with polycystic ovarian syndrome by Stanosz S1, von Mach-Szczypiński J, Sieja K, Koœciuszkiewicz J.(PubMed)
(225) The percentages of endometrial hyperplasia and endometrial cancer among polycystic ovary syndrome (PCOS) patients presenting with abnormal menstrual pattern by Prakansamut N, Sirayapiwat P, Triratanachat S.(PubMed)
(226) PCOS and obesity: insulin resistance might be a common etiology for the development of type I endometrial carcinoma by Li X1, Shao R2(PubMed)
(227) Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential by Piltonen TT1, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC.(PubMed)
(229) The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome - a proof-of-concept study by Shafiee MN1, Malik DA, Yunos RI, Atiomo W, Omar MH, Ghani NA, Hatta AZ, Seedhouse C, Chapman C, Mokhtar NM.(PubMed)
(230) Micronized estradiol and progesterone therapy in primary, preinvasive endometrial cancer (1A/G1) in young women with polycystic ovarian syndrome by Stanosz S1, von Mach-Szczypiński J, Sieja K, Koœciuszkiewicz J.(PubMed)
(231) Berberine and monacolin effects on the cardiovascular risk profile of women with oestroprogestin-induced hypercholesterolemia by Cicero AF1, Reggi A, Parini A, Morbini M, Rosticci M, Grandi E, Borghi C.(PubMed)
(232) Effects of long-term administration of an oral contraceptive containing ethinylestradiol and cyproterone acetate on lipid metabolism in women with polycystic ovary syndrome by Falsetti L1, Pasinetti E.(PubMed)
(233) Polycystic Ovary Syndrome and the Metabolic Syndrome by Julie L. Sharpless, MD(American diabeyes association)
(234) Pathophysiology and types of dyslipidemia in PCOS by Diamanti-Kandarakis E1, Papavassiliou AG, Kandarakis SA, Chrousos GP(PubMed)
(235) Dyslipidaemia in polycystic ovarian syndrome: different groups, different aetiologies? by Meirow D1, Raz I, Yossepowitch O, Brzezinski A, Rosler A, Schenker JG, Berry EM.(PubMed)
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The Best of smoothie's recipes: Pomegranate hibiscus tea cooler
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The (safe, nutritious, easy to prepare snacks for any occasion) ultimate allergy-free snack cookbook by Judi and Shari Zucker, Square one publishers. Over 100 kid -friendly recipes for the allergic child.
Similar to the favor to cranberries, hibiscus herbal tea is blended with juice with pomegranate - a super food known for its healthy benefits - in this refreshing drink. We prefer using herbal tea because it's caffeine free.
Yield 4 servings, about 8 ounces each.
6 hibiscus herbal tea bags
2 cups boiling water
2 cups cold water
1 cup pomegranate juice
Lemon wedges for garnish (optional)
1. Steep the tea bags into boiling water for about 5 minutes. Remove tea bags and pour the tea into pitcher.
2. Add cold water and pomegranate juice and stir well. Refrigerate about 2 hours or until ice cold.
3. Serve as is or over ice cubes. Garnish with lemon wedge.
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The (safe, nutritious, easy to prepare snacks for any occasion) ultimate allergy-free snack cookbook by Judi and Shari Zucker, Square one publishers. Over 100 kid -friendly recipes for the allergic child.
Similar to the favor to cranberries, hibiscus herbal tea is blended with juice with pomegranate - a super food known for its healthy benefits - in this refreshing drink. We prefer using herbal tea because it's caffeine free.
Yield 4 servings, about 8 ounces each.
6 hibiscus herbal tea bags
2 cups boiling water
2 cups cold water
1 cup pomegranate juice
Lemon wedges for garnish (optional)
1. Steep the tea bags into boiling water for about 5 minutes. Remove tea bags and pour the tea into pitcher.
2. Add cold water and pomegranate juice and stir well. Refrigerate about 2 hours or until ice cold.
3. Serve as is or over ice cubes. Garnish with lemon wedge.
For Over 1000 recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
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