Saturday, 27 September 2014

Weight Loss Recipe 4 Salmon Lovers: Sweet fire salmon

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Recipe contributed by eat well and lose weight by better Holmesd and Gardens (more than 500 delicious satisfying recipes), published by Houghton Miffin Harcourt. You can view its website at www.hmhbooks.com

Preheat oven to 450 degree F. Combine 1/2 teaspoon each chili powder and brown sugar, Sprinkle mixture over one 3 ounces salmon fillet; rub in. Roast salmon for 15 minutes or until it fakes with a fork. Meanwhile, in a small microwave-safe bowl combine 1/2 cup cooked brown rice; 1/4 frozen peas, thawed; and 1 green onion, sliced. Microwave for 1 minute. slice half of a cucumber; drizzle 2 teaspoon cider vinegar and 1/2 teaspoon olive oil. Serve salmon with rice mixture, cucumber mixture and lime wedges.
Per serving; 370 cal., 15g fat (3g sat. fat), 47mg chol., 72 mg soldium, 36g carb., 7g sugar, 5g fiber, 23g pro.
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Friday, 26 September 2014

Endometriosis: The Effects of Vitamin C(revised edition with references)

By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood. Instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
Vitamin C, also known as L-ascorbate is a water soluble vitamin with a chemical structure formula of C6H6O6 and cannot be stored in the body for more than 24 hours. We are required to take it regularly. It is also best known for it's antioxidant property in strengthening the immune system.

1. Immune system(1)
Vitamin C plays an important role in strengthening the immune system because of it's powerful antioxidant property(2). It helps to guard our body against the forming of free radicals(3) and abnormal growth of endometrial cells in other parts of the body.

2. Increase absorption of digestive system
Most women with endometriosis are found to have deficiency of some kinds of vitamins and minerals such as vitamin B complex, folic acid, zinc, and magnesium. Increasing intake of vitamin C not only helps to improve digestive absorption(6)(7), but also increases the body's function in fighting against all kinds of diseases(8) including endometriosis.

3. Endometrial related pain
Besides helping strengthen the liver function to balance the estrogen level(5) during menstrual cycle, vitamin C also balances the level of prostaglandins hormones in the prostaglandins family resulting in the calming of over-active uterine muscles(4).

4. Reduce heavy blood flow and blood clotting(10)
Vitamin C not only helps to protect the breaking off of the capillaries that cause heavy blood flow(11) for women with endometriosis during menstruation but also prevents blood clotting(9) caused by reduction of prothrombin, thrombin, and thrombokinase concentrations in the body.

5. Decrease infection and inflammation
Vitamin C helps in protein metabolism. It not only provides our body with certain necessary proteins but also blocks the synthesis of vital proteins that cause infection(14)(15) and inflammation(8)(12)(13).
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Refrerences
(1)[Vitamin C and its physiological role with respect to the components of the immune system][Article in Czech] by Holmannová D1, Koláčková M, Krejsek J.(PubMed)
(2) Vitamin C. Give a boost to your immune system by Webb R.(PubMed)
(3) Antioxidants, inflammation and cardiovascular disease by Mangge H, Becker K, Fuchs D, Gostner JM.(PubMed)
(4) Antioxidant supplementation reduces endometriosis-related pelvic pain in humans by Santanam N1, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S.(PubMed)
(5) Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model by Nematbakhsh M1, Pezeshki Z, Eshraghi-Jazi F, Ashrafi F, Nasri H, Talebi A, Safari T, Haghighi M, Mansouri A.(PubMed)
(6) [Diminution of digestive absorption of vitamin C in the course of cirrhosis].[Article in French] by WARTER J, SCHIRARDIN H, METAIS P.(PubMed)
(7) [Vitamin C treatment of digestive disorders from intolerance to PAS absorption].[Article in Undetermined Language] by PICHAT.(PubMed)
(8)Vitamin C as an antioxidant: evaluation of its role in disease prevention. by Padayatty SJ1, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M.(PubMed)
(9) Impaired capacity for acute endogenous fibrinolysis in smokers is restored by ascorbic acidby Kaehler J1, Koeke K, Karstens M, Schneppenheim R, Meinertz T, Heitzer T.(PubMed)
(10) [The significance of changes in the functional properties of blood platelets, factor XIII activity and fibrin clot quality in the pathogenesis of hemorrhagic diathesis secondary to experimental vitamin C deficiency].[Article in Russian] by Sushkevich GN, Khnychev SS, Oĭvin VI.(PubMed)
(11) Functional menorrhagia: treatment with bioflavonoids and vitamin C by COHEN JD, RUBIN HW.(PubMed)
(12) Effect of high-dose intravenous vitamin C on inflammation in cancer patients by Mikirova N1, Casciari J, Rogers A, Taylor P.(PubMed)
(13) Vitamin C further improves the protective effect of glucagon-like peptide-1 on acute hypoglycemia-induced oxidative stress, inflammation, and endothelial dysfunction in type 1 diabetes by Ceriello A1, Novials A, Ortega E, Canivell S, La Sala L, Pujadas G, Bucciarelli L, Rondinelli M, Genovese S.(PubMed)
(14) Effects of high dose vitamin C treatment on Helicobacter pylori infection and total vitamin C concentration in gastric juice by Jarosz M1, Dzieniszewski J, Dabrowska-Ufniarz E, Wartanowicz M, Ziemlanski S, Reed PI.(PubMed)
(15) Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection by Kim Y1, Kim H, Bae S, Choi J, Lim SY, Lee N, Kong JM, Hwang YI, Kang JS, Lee WJ.(PubMed)














Weight Loss Recipe for Spiciers - Spicy Tortilla Chip


Recipe contributed by eat well and lose weight by better Holmesd and Gardens (more than 500 delicious satisfying recipes), published by Houghton Miffin Harcourt. You can view its website at www.hmhbooks.com


Preheat oven to 350 degree F. In a small cup combine 1/4 teaspoon each chili powder and garlic powder and a dash od salt. Cut one 8 inch trotilla into wedges; coat with non stick spray and sprinkle with chili powder mixture. Bake for 8 - 10 minutes or until lightly browned. Meanwhile for salsa, combine 1/2 cup chopped tomatoes, 2 table spoons finely chopped onion, 2 teaspoon lime juices, 1and 1/2 teaspoons sipped fresh cilantro, and 1 teaspoon finely chopped jalapeno pepper. Serve with tortilla wedges and 1 ounce of reduced cheddar cheese.
Per serving; 2743 cal., 9g fat (4g sat. fat), 15mg chol., 660mg sodium, 23 carb., 5g sugar, 12g fober, 17g pro.

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will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
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Thursday, 25 September 2014

The Healthy Weight LOss Recipe: Nutty 'N' spicy noodle

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Recipe contributed by eat well and lose weight by better Holmesd and Gardens (more than 500 delicious satisfying recipes), published by Houghton Miffin Harcourt. You can view its website at www.hmhbooks.com


In a small bowl whisk together 1 tablespoon reduced sodium soy sauce, 2 teaspoon peanut butter, 1 teaspoon lime juice, 1/8 teaspoon sesame oil, and a dash crushed red pepper. Toss mixture with a cup cucumber, and 1/4 cup shredded carrot. Cover and chill up to 2 hours. Serve with orange.
Per serving; 38/2 cal., 8 g fat (1g sat sat. fat), 0mg chol., 623 mg sodium, 64 carb., 21 g sugar, 9 g fiber, 16g pro.
Weight Loss the Easy Ways 
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will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

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Wednesday, 24 September 2014

The Best Weight LOss recipe: Santa fe breakfat wrap

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Recipe contributed by eat well and lose weight by better Holmesd and Gardens (more than 500 delicious satisfying recipes), published by Houghton Miffin Harcourt. You can view its website at www.hmhbooks.com

In a small bowl whisk 2 eggs, 2 tablespoon milk, and 1/8 teaspoon each salt and black paper. lightly coat a medium skillet with nonstick cooking spray; heat over medium heat. Pour egg mixture into skillet. Cook, stirring egg from edges toward center of skillet. When center is set, remove from heat; fold in half avocado, chopped. Spoon mixture onto 9- inch whole grain tortilla; add 2 tablespoons salsa and 1 teaspoon chopped green onion.
Per serving; 484g cal., 25g fat(6g satured fat), 425 mg chol., 1,159 mg soldium, 45g carb., 5g sugar, 11g fiber, 21g pro.

Weight Loss the Easy Ways 
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple WaySuper foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html

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Tuesday, 23 September 2014

Endometriosis: The Good, The Bad and The Side Effects of The Pill(Revised edition with references)

By Kyle J. NortonHealth article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood. Instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.

The Pill normally is prescribed by your doctor to reduce the heavy period blood for woman with or with out endometriosis as well as in treating of period pain, or contraceptive purpose ( 21 days on and 7 days off).

A. The Good(Effectiveness)
1. Reduce the period blood flow(1) as resulting in lowering the risk of more developing of endometriosis(2).
2. Reduce the bleeding(1) by thinning the endometrial lining.
3. Reduce the period pain(3) by inhibiting the hormone prostaglandins hormones that cause the uterine muscles spasm(2).
4. Shrink the endometriosis and reduce the bleeding of into cysts and pelvic cavity(3) because the Pill creates the pregnant-like state.
5. Suppress the estrogen that is needed to start a menstrual cycle(5)(6).

B. The Bad(The Risks)
1. Blood clots
All hormonal methods of birth control pose a threat to normal blood flow. The oral contraceptive combination pill is no exception, it increases the risk of blood clots in your legs or on the lung caused by estrogen in the pill that makes your blood thicker in the veins(7)(8).

2. Stroke(9)(10)
Woman who takes the oral contraceptive combination pill increases the risk of stroke caused by blockage of blood flow to the brain as resulting of high level of estrogen in the pill that reduces the oxygen transportation as the blood getting thicker.

3. Heart disease(11)
Similar to the stroke, as our blood get thicker, our heart has to pump harder to provide oxygen for our body cells need causing hypertension. If our heart has to work that hard for a prolong period of time because of long term use of birth control pill, it will be damaged causing heart disease.

4. Skin pigment(12)(13)
Some woman may experience increasing of pigmentation of skin that shows up in patchy and light brown area caused by estrogen in the pill.

5. Mood swing(14)
Some women may experience mood swing while taking the pill, it is caused by significant changes in your hormone levels affecting the chemicals that regulate mood such as level of estrogen and progesterone in the pill.

6. Infertility(15)(16)
Some women after coming off the birth control pill and hope to get pregnant, they may be disappointed. Not only the effects of birth control pill maybe needed sometime to wire off, our body may never be able to adjust causing lost of period permanently and induced risk ovarian cancer.

7. Increase the risk of fibroids but decreased with duration of oral contraceptive use(17)
Oral contraceptive combination pill contains estrogen that promote the growth of fibroids. If you have fibroids and you want take the oral contraceptive pill, you should talk to your doctor first.

C. The  Side effects
1. Bleeding and spotting(18)
Bleeding and spotting is normal for the first six months for women starting any oral contraceptive combination pill because our body needs time to adjust to the new medication.

2. Lost interest in sex
Women who take the contraceptive pill are in danger of permanently lost their interest in sex because the oral contraceptive pill inhibits testosterone, the hormone that drives sexual desire even after if they stop the pill(19).

3. Chloasma or melisma(12)(13)
It caused by hormonal changes, as in pregnancy and intake of estrogen in the oral contraceptive pill.

4. Nutritional deficiency(20)(21)
Oral contraceptive pill causes vitamin and mineral imbalances or deficiencies. It depletes magnesium for healthy heart, coenzyme Q10 for healthy heart muscles, folic acid for preventing cervical abnormalities, vitamin B6, B2, B3, zinc, etc.

5. Alternation of emotion in facial expression
The pill may alter the detection of emotions in facial expressions, according to the study by 1Institute of Psychology, Clinical Psychology Department, Leiden University(4).

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Celebrity Patti Stanger Will Coach You To Get Him/Her
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References
(1) Satisfaction and health-related quality of life in women with heavy menstrual bleeding; results from a non-interventional trial of the levonorgestrel-releasing intrauterine system or conventional medical therapy by Xu L1, Lee BS2, Asif S3, Kraemer P4, Inki P5.(PubMed)
(2) Combined oral contraceptives: health benefits beyond contraception by Caserta D1, Ralli E, Matteucci E, Bordi G, Mallozzi M, Moscarini M.(PubMed)
(3) Low-dose oral contraceptive pill for dysmenorrhea associated with endometriosis: a placebo-controlled, double-blind, randomized trial by Harada T1, Momoeda M, Taketani Y, Hoshiai H, Terakawa N.(PubMed)
(4) Oral contraceptives may alter the detection of emotions in facial expressions by Hamstra DA1, De Rover M2, De Rijk RH3, Van der Does W4.(PubMed)
(5) Menstrual suppression for adolescents by Altshuler AL1, Hillard PJ.(PubMed)
(6) Menstrual suppression: current perspectives by Hillard PA.(PubMed)
(7) Debating the evidence: oral contraceptives containing drospirenone and risk of blood clots by Dodd S.(PubMed)
(8) Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9 by Lidegaard Ø1, Nielsen LH, Skovlund CW, Skjeldestad FE, Løkkegaard E.(PubMed)
(9) Risk of ischemic stroke among users of the oral contraceptive pill: The Melbourne Risk Factor Study (MERFS) Group by Siritho S1, Thrift AG, McNeil JJ, You RX, Davis SM, Donnan GA; Melbourne Risk Factor Study (MERFS) Group.(PubMed)
(10) Use of low-dose oral contraceptives and stroke in young women by Schwartz SM1, Siscovick DS, Longstreth WT Jr, Psaty BM, Beverly RK, Raghunathan TE, Lin D, Koepsell TD.(PubMed)
(11) Prospective measurement of blood pressure and heart rate over 24 h in women using combined oral contraceptives with estradiol by Grandi G1, Xholli A1, Napolitano A1, Piacenti I1, Bellafronte M1, Cagnacci A2.(PubMed)
(12). [Dermal changes in response to hormonal contraceptives (author's transl)].[Article in German]by Scholz C, Donat H.(PubMed)
(13) Melasma and other skin manifestations or oral contraceptives by Resnik SS.(PubMed)
(14) Comparison of scales for evaluating premenstrual symptoms in women using oral contraceptives by Coffee AL1, Kuehl TJ, Sulak PJ.(PubMed)
(15) Association of oral contraceptive use, other contraceptive methods, and infertility with ovarian cancer risk by Tworoger SS1, Fairfield KM, Colditz GA, Rosner BA, Hankinson SE.(PubMed)
(16) Primary infertility and oral contraceptive steroid use by Bagwell MA1, Thompson SJ, Addy CL, Coker AL, Baker ER.(PubMed)
(17) Use of oral contraceptives and uterine fibroids: results from a case-control study by Chiaffarino F1, Parazzini F, La Vecchia C, Marsico S, Surace M, Ricci E.(PubMed)
(18) Efficacy and safety of an ascending-dose, extended-regimen levonorgestrel/ethinyl estradiol combined oral contraceptive by Portman DJ1, Kaunitz AM2, Howard B3, Weiss H4, Hsieh J5, Ricciotti N6.(PubMed)
(19) Hormonal contraception and mental health: results of a population-based study by Toffol E1, Heikinheimo O, Koponen P, Luoto R, Partonen T.(PubMed)
(20) Biological variability and impact of oral contraceptives on vitamins B(6), B(12) and folate status in women of reproductive age by McArthur JO1, Tang H, Petocz P, Samman S.(PubMed)
(21) Oral contraceptives and changes in nutritional requirements by Palmery M1, Saraceno A, Vaiarelli A, Carlomagno G.(PubMed)

Endometriosis: The Effects of Biotin (revised edition with references)

By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.

Biotin, one of the members of the vitamin B complex, also known as vitamin H or B7 is a co-factor in the metabolism of fatty acids, leucine, and in gluconeogenesis. It has a chemical structure formula of C10H16N2O3S. Deficiency is extremely rare, as intestinal bacteria generally produce an excess of the body's daily requirement but for what ever reason, women with endometriosis are found to have low levels of biotin.

1. Cell abnormality(1)(2)
Biotin acts as a co-factor with the other members in the vitamin B complex. It plays an important role in managing the body's cell growth(3). Without enough biotin, it causes cell growth abnormality such as the forming of perinatal cells into endometrial cell in the abdominal regions.

2. Poor blood circulation
Since biotin helps in gluconeogenesis(5), it regulates the sugar levels in the blood stream(4). Without enough levels of biotin, the level of blood sugar rises causing the thickening of blood which reduces the circulatory function and blocks the transportation of nutrients and oxygen to our body's cells. This results in an increased risk of symptoms of endometriosis.

3. Menstrual cramps(8)
Since biotin is necessary in the metabolism of fatty acids, it helps to maintain levels of prostaglandins. Deficiency of biotin causes some members in the prostaglandins family to be over-produced during the menstrual cycle leading to menstrual and endometrial cramps.

4. Respiratory problem(6)(7)
Since biotin helps to synthesize carbon dioxide, without enough biotin it causes shortness of breath in women with endometriosis.

5. Risk of heart disease(9) and stroke(10)
If the liver cannot produce enough bile to generate good cholesterol because of not enough amounts of biotin in the body, it leads to cholesterol building up in the arteries causing the thickening of the arterial wall and the blockage o circulation of blood resulting in an increased risk of heart disease and stroke.

6. Weaken function of nervous system(11)(12)
Since biotin acts as a co-factor with other vitamin B complexes in the metabolism of protein, deficiency of biotin interferes with that process. It weakens the normal functions of cells in the nervous system leading to tension of the nervous system such as anxiety, dizziness, loss of memory, and depression.

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References
(1) Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell-cell and cell-substrate adhesion by Van Itallie CM1, Tietgens AJ, Aponte A, Fredriksson K, Fanning AS, Gucek M, Anderson JM.(PubMed)
(2) Effects of biotin supplementation in the diet on insulin secretion, islet gene expression, glucose homeostasis and beta-cell proportion by Lazo de la Vega-Monroy ML1, Larrieta E, German MS, Baez-Saldana A, Fernandez-Mejia C.(PubMed)
(3) Biotin requirements for DNA damage prevention by Zempleni J1, Teixeira DC, Kuroishi T, Cordonier EL, Baier S.(PubMed)
(4) Influence of a deficiency in biotin on the activity of pyruvate carboxylase and on gluconeogenesis from [14C]pyruvates or bicarbonate in mice by Mayobre ML, Pasquier S, Favarger P, Rous S.(PubMed)
(5) Altered glucagon release in biotin deficiency by Klandorf H, Clarke BL, Brown J.(PubMed)
(6) Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblasts by Atamna H1, Newberry J, Erlitzki R, Schultz CS, Ames BN.(PubMed)
(7 ) [Prospective study of biotin treatment in patients with erythema due to gefitinib or erlotinib].
[Article in Japanese] by Ogawa Y1, Kiba T, Nakano K, Fujiwara K, Taniguchi H, Hosokawa A, Nakashima T, Kimoto S, Kajiume S, Okada Y, Ichiba Y.(PubMed)
(8) Biotin ameliorates muscle cramps of hemodialysis patients: a prospective trial by Oguma S1, Ando I, Hirose T, Totsune K, Sekino H, Sato H, Imai Y, Fujiwara M.(PubMed) 
(9) [Effect of lipoic acid, biotin and pyridoxine on blood content of saturated and unsaturated fatty acids in ischemic heart disease and hypertension].[Article in Russian]by Vodoevich VP.(PubMed
(10) Antihypertensive effect of biotin in stroke-prone spontaneously hypertensive rats by Watanabe-Kamiyama M1, Kamiyama S, Horiuchi K, Ohinata K, Shirakawa H, Furukawa Y, Komai M.(PubMed
(11) Biotin is endogenously expressed in select regions of the rat central nervous system by McKay BE1, Molineux ML, Turner RW.(PubMed
(12) Biotin transport and metabolism in the central nervous system by Spector R1, Mock DM.(PubMed)