Food Therapy - Beet (Beta vulgaris) and Hypertension

Beet is best known as the beetroot or garden beet and belong to the amaranth family. It is a perennial plant with leafy stems growing to 1–2 m tall.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising pressure in your heart.If it stays high over time it can damage the body in many ways.

Nutrients and chemical Constituents
1. Energy
2. Carbohydrates
3. fiber
4. Protein
5. Vitamin A
6. Beta-carotene
7. Trytophan
8. Thiamine (Vitamin B1)
9. Riboflavin (Vitamin B2)
10. Niacin (Vitamin B3)
11. Pantothenic acid (Vitamin B5)
12. Vitamin B6
13. Folate (Vitamin B9)
14. Vitamin C
15. Calcium
16. Iron
17. Magnesium
18. Copper
19. Phosphorus
20. Potassium
21. Zinc
22. Magnesium
23. Betacyanin
24. Betaine
25. Etc.
Beside the major chemical constituents betalains and phenolics, it also contains lesser amount of isobetanin, probetanin, neobetanin, indicaxanthin, vulgaxanthins, etc.

The Benefits
Consumption of beetroot juice on a low nitrate diet is said to lower blood pressure (BP) and therefore reduce the risk of cardiovascular events. In a fifteen women and fifteen men participated in a double-blind, randomized, placebo-controlled, crossover study, showed a positive effect of beetroot juice in addition to a normal diet in men. Other study also found a low dose of 100g exerts the significant hypotensive effects which was unaffected by processing or the presence of betacyanins. Also enriching bread with beetroot may be a suitable vehicle to increase intakes of cardioprotective beetroot in the diet and may provide new therapeutic perspectives in the management of hypertension.

Side effects
1. Oxalates
 Oxalates in the beet can cause kidney and gallbadder problem. People with above diseases should contact their doctor before consuming.
2. Increase the rick of lowering calcium absorption for people with weak digestive system.
3. Etc.



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References
(1) Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: a randomized, placebo-controlled trial by Coles LT, Clifton PM.(PubMed)
(2) Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: a randomized, placebo-controlled trial by Coles LT, Clifton PM.(PubMed)
(3) Acute ingestion of beetroot bread increases endothelium-independent vasodilation and lowers diastolic blood pressure in healthy men: a randomized controlled trial by Hobbs DA, Goulding MG, Nguyen A, Malaver T, Walker CF, George TW, Methven L, Lovegrove JA.(PubMed)

Herbal Butterbur and hyperreactivity

Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere. It has been used in herbal medicne used as an pain reliever in digestive system, including stomach, bile ducts, and duodenum, etc. 
Airway hyperreactivity is a defined as a condition of easily triggered bronchospasm as a result of physical, chemical, or pharmacologic stimuli.

The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene,  quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.

The benefits
Extract (Ze 339, PET) from herbal Petasites hybridus (butterbur) is found to be effective in inhibiting the
nhibited airway hyperresponsiveness by inhibiting the production of the Th2 cytokines IL-4 and IL-5, and RANTES. S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus may also be used as a bronchodilator in the treatment of on obstructive airway hyperresponsiveness, including chronic obstructive pulmonary disease and asthma exacerbations.
 
Side effects
1. Butterbur may be liver-toxic to liver and cause cancer due to the presence of pyrrolizidine alkaloids(a)
2. If you are pregnant please do not use Butterbur with out the permission of the related special field specialist
3. Allergic effect to certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
5. Etc.

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References
(1) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
(2) Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness by Lin LH, Huang TJ, Wang SH, Lin YL, Wu SN, Ko WC.(PubMed)

Herbal Butcher's broom and Inflammatory effects

Butcher's broom is a low evergreen shrub, a species of Ruscus aculeatus, belonging to the family Asparagaceae, native to Eurasia.It has been used in herbal medicine to treat reduce inflammation, Peripheral vascular disease, Hemorrhoids Bronchial asthma, Varicose veins, Hypotension, Jaundice, functional disorders of the heart, kidney disorder, venotonic and anti-oedematous properties, etc..
Inflammation is a condition of Immune system self-protection to remove harmful stimuli, including damaged cells, irritants, pathogens... from our body.

The Ingredients
It contains rutin, sitosterol, sparteine, spirostanol saponins, steroidal sapogenins, sterols, stigmasterol, sulfated steroidal saponins, sweet broom, tetracosanoic acid, triterpenes, triterpines, tyramine, etc.

The benefits
Ruscogenin (RUS), isolated from Ruscus aculeatus, has been found to exert significant anti-inflammatory and anti-thrombotic activities by inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. Other study also showed ruscogenin resulted in markedly reduced expression of inflammatory cytokine and leukocyte infiltration via the inhibition of nuclear factor (NF)-κB activity in rat lungs.

The Side effects
1. Do not use if you are pregnant with out permission of related field specialist, as Sparteine may increase uterine contraction
2. Do not use Butcher's broom if you are taking any form of monoamine oxidaseinhibitor
3. Use as direction and do not overdose
4. Etc.


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References
(1) Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB by Huang YL, Kou JP, Ma L, Song JX, Yu BY.(PubMed)
(2) Ruscogenin attenuates monocrotaline-induced pulmonary hypertension in rats  by Bi LQ, Zhu R, Kong H, Wu SL, Li N, Zuo XR, Zhou SM, Kou JP, Yu BY, Wang H, Xie WP.(PubMed)

Herbal Burdock and Antibacterial activity

Burdock is plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro. It has been used over thousand of years in Chins and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises of the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Beside foods and nutritional supplements, herbs also play a important role in helping the immune system defend against viruses and bacteria attacks.

The benefits
An ethyl acetate fraction (AcOEt) extracted from Arctium lappa or Burdock has exerted its anti bacterial effective in the testing of Pseudomonas aeruginosa, Escherichia coli, Lactobacillus acidophilus, Streptococcus mutans and Candida albicans. Its rough extracts from leaves of Arctium lappa, also exhibited specificity against the target microorganisms and may be a potential effective  in the tested endodontic pathogens. Other in the study of Extracts of 13 Brazilian medicinal plants  for their antimicrobial activity against bacteria and yeasts, including Burdock, suggested that the herb may be a ethnobotanical use of the studied species for the treatment of various infectious diseases.


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References
(1) In vitro evaluation of the antibacterial activity of Arctium lappa as a phytotherapeutic agent used in intracanal dressings by Gentil M, Pereira JV, Sousa YT, Pietro R, Neto MD, Vansan LP, de Castro França S.(PubMed)
(2) Antimicrobial activity of Arctium lappa constituents against microorganisms commonly found in endodontic infections by Pereira JV, Bergamo DC, Pereira JO, França Sde C, Pietro RC, Silva-Sousa YT.(PubMed)
(3) Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases by Holetz FB, Pessini GL, Sanches NR, Cortez DA, Nakamura CV, Filho BP.(PubMed)

Herbal Arctostaphylos uva-ursi and antiinflammatory activities

Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to the northern North America, Asia and Europe. The herb has been used in traditional medicine as diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stone, pelvic pain, etc.
Inflammation is a condition of Immune system self-protection to remove harmful stimuli, including damaged cells, irritants, pathogens... from our body.

The Ingredients It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins,  phenolic glycosides and flavonoids.

The benefits
Water extract (UW-ext) collected from the the leaf of Arctostaphylos uva-ursi (L.) Spreng (Bearberry leaf), is found to exhibit its anti-inflammatory effects in ear swelling by picryl chloride-induced contact dermatitis (PC-CD) and carrageenin-induced paw edema. arbutin isolated from the leaves of Arctostaphylos uva-ursi (L.) Spreng., when combined with and indomethacin on Type IV allergic reaction-induced immuno-inflammation, carrageenin-induced edema and adjuvant-induced arthritis, found to be effective as arbutin may increase the inhibitory action of indomethacin on PC-CD, SRBC-DTH, carrageenin-induced edema and adjuvant-induced arthritis, but further investigations are required to understand the mechanism involved. Other study also indicated that 50% methanolic extract (U-ext), containing arbutin, possesses a therapeutic effect against immuno-inflammation induced by  by picryl chloride (PC-CD) and also increases the inhibitory effect of prednisolone.

The Side effect
1. Overdoses may cause gastrointestinal discomfort, including cause nausea, vomiting, etc. and fever, chills, severe back pain, ringing in the ears, etc.
2. The herb may interact with other medicine, including diuretic
3. Do not use the herb in new born, children or if you are pregnant or breast feeding without approval from the related field specialist.
4. Etc.


Chinese Secrets To Fatty Liver And Obesity Reversal
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. V. Effect of water extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on the antiallergic and antiinflammatory activities of dexamethasone ointment].[Article in Japanese] by Matsuda H, Nakamura S, Tanaka T, Kubo M.(PubMed)
(2) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. III. Combined effect of arbutin and indomethacin on immuno-inflammation].[Article in Japanese] by Matsuda H, Tanaka T, Kubo M.(PubMed)
(3) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. I. Combined effect of 50% methanolic extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) and prednisolone on immuno-inflammation].[Article in Japanese] by Kubo M, Ito M, Nakata H, Matsuda H.(PubMed)

Herbal Andrographis and Anti-fertility

Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka. It has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
Anti-fertility is an act with intention to prevent, reduce or destroy fertility by using substances such as contraceptives, herbal medicine in under developing world.

The Ingredients
Beside the main ingredient andrographolides, giving the plant a bitter taste, other ingredients includediterpene lactones, such as: neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.

The Benefits
Kan Jang--a fixed combination of Andrographis paniculata special extract (SHA-10) and Acanthopanax senticosus, although the herbal mix extract revealed no significant negative effect on male semen quality and fertility, but rather a positive trend with respect to the number of spermatozoids in the whole ejaculate, the percentage of active (normokinetic) forms of spermatozoids, and fertility indexes, together with a decrease in the percentage of inactive (diskinetic) forms of spermatozoids. Dry leaf powder of A. paniculata increases the risk accumulating of glycogen and cholesterol in the testis, and increased activities of lactate dehydrogenase in testis and alkaline phosphatase in testis and ventral prostate, thus reducing the risk of fertility. But in other study, Extract of Andrographis paniculata Nees (A paniculata) standardized to >or=10% andrographolide, have found to be no effect on total sperm count and sperm motility and levels of testosteroneand fertility indices in treatment groups were found to be comparable with that of the control in rats.

The Side effects
 People with gallbladder disease may want to consult with their doctor before using because of the herb stimulating gallbladder contraction effect.


Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html
References
(1) Antifertility effect of Andrographis paniculata (Nees) in male albino rat by Akbarsha MA, Manivannan B, Hamid KS, Vijayan B.(PubMed)
(2) A phase I clinical study of Andrographis paniculata fixed combination Kan Jang versus ginseng and valerian on the semen quality of healthy male subjects by Mkrtchyan A, Panosyan V, Panossian A, Wikman G, Wagner H.(PubMed)
(3) Reproductive and fertility effects of an extract of Andrographis paniculata in male Wistar rats, by Allan JJ, Pore MP, Deepak M, Murali B, Mayachari AS, Agarwal A.(PubMed)

Antioxidants and Non alcoholic fatty liver disease (NAFLD)

A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with other cell, which in turn, causes oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospho-lipids, DNA and RNA, etc., leading to aging of the organisms, as a result of widespread damage due to set of a chain reaction auto-catalytically after attacking the lipid bilayers of the cell walls.
Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.  

Antioxidants have been found to assist the body in selfrepairment of the cell damage caused by oxidative stress in balancing of the electrons. Oxidative stress is found to cause hepatic damage in patients with acute and chronic hepatitis B virus (HBV) infection and these imbalances in some researches were found to be associated in patients with Non alcoholic fatty liver disease (NAFLD). In a prospective study of 29 patients with NAFLD, 25 diseased controls with chronic viral hepatitis, and 23 healthy controls, lipid peroxidation are significantly increased among patients with NAFLD compared to healthy subjects, but there were no significant correlation between histological grading or staging and levels of pro and antioxidants. This study demonstrate that oxidative may be considered as a potential cause in managing patients with Non alcoholic fatty disease.

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References
(1) Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD).

Madan K, Bhardwaj P, Thareja S, Gupta SD, Saraya A.(PubMed)

(2) [Investigation of oxidative stress and antioxidant defense in patients with hepatitis B virus infection and the effect of interferon-alpha plus lamivudine combination therapy on oxidative stress].[Article in Turkish. by Acar A, Görenek L, Aydin A, Eyigün CP, Eken A, Sayal A, Pahsa A.(PubMed)