Alfalfa is a flowering plant in the genus Medicago, belonging
to the family Fabaceae, It has been cultivated all over the world as
hay for cattle feeding. The leaves, sprouts, and seeds to make
medicine has been used in traditional medicine over thousands of year
to treat high cholesterol, asthma, osteoarthritis, rheumatoid
arthritis, diabetes, enhance digestive system, bleeding disorder,
kidney and urinary tract infection, etc. North America aboriginal has
used Alfalfa seed as food, such as making bread and mush.
Diabetes is defined as a condition caused by insufficient
insulin entering the bloodstream to regulate the glucose. It is either
caused by cells in pancreas dying off or receptor sites clogged up by
fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Ingredients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
13. Etc.
It chemical constituents include flavones, isoflavones, sterols,
Bichanin, Coumestrol, Diadzein, Formonetin, Genistein, coumarin derivatives,
etc.
The benefits
herbal alfalfa has so far been used for the treatment and management of
various ailments since the beginning of human civilization. In the
review therapeutic potential of M. sativa,
Sequential extraction of alfalfa with solvents revealed
insulin-releasing activity in both methanol and water fractions. In
other study of normal and streptozotocin diabetic mice, indicated
that certain traditional plant treatments for diabetes, including alfalfa retard the development of streptozotocin diabetes
in mice. Regardless to the outcome, long-term multiple dietary
supplement users consumed a broad array of vitamin/mineral, herbal, and
condition-specific dietary supplements on a daily basis should consult
with their doctors or related field specialist before applying.
The Side effects
1. High amount of vitamin K may reduce the effectiveness of anticogulation medicine
2. Causing additive effects for women who are under estrogen replacement therapy or taking the oral contraceptive pill.
3. It may cause stomach upset and diarrhea
4. The herb may induce lupus erythematosu due to its chemical constituent L-canavanine.
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References
(1) Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM, Flatt PR.(PubMed)
(2) Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR.(PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)
Friday, 3 January 2014
Herbal Andrographis and Cancers
Andrographis paniculata
is also known as Andrographis is a herbaceous plant, genus
Andrographis, belonging to the family Acanthaceae, native to India and
Sri Lanka. It has been used in traditional Siddha and Ayurvedic in
treating the common cold, flu, upper respiratory infections, infectious
diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes,
leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
The Ingredients
Beside the main ingredient andrographolides, giving the plant a bitter taste, other ingredients includediterpene lactones, such as: neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
Beside the main ingredient andrographolides, giving the plant a bitter taste, other ingredients includediterpene lactones, such as: neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
The benefits
Andrographolide (Andro), a diterpenoid, isolated from Andrographis paniculata, has exerted it anti-proliferative and pro-apoptotic effects from sequenced
combinations of andrographolide and cisplatin on ovarian cancer cell
lines. In other study, Andrographolide, a chemical constituent isolated from the Leaves of Andrographis
paniculata Nees, significantly reduced the expression of hVEGF-A165
compared with a mock group in the Clara cells of the lungs and its
anticancer and immunomodulatory activities may be potential to provide a
cure for pulmonary tumors and a cancer therapeutic agent in the future.
The Side effects
1. Antifertility
Dry leaf powder of A. paniculata increases the risk accumulating of glycogen and cholesterol in the testis, and increased activities of lactate dehydrogenase in testis and alkaline phosphatase in testis and ventral prostate, thus reducing the risk of fertility.
2. People with gallbladder disease may want to consult with their doctor before using because of the herb stimulating gallbladder contraction effect.
3. Etc.
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1. Antifertility
Dry leaf powder of A. paniculata increases the risk accumulating of glycogen and cholesterol in the testis, and increased activities of lactate dehydrogenase in testis and alkaline phosphatase in testis and ventral prostate, thus reducing the risk of fertility.
2. People with gallbladder disease may want to consult with their doctor before using because of the herb stimulating gallbladder contraction effect.
3. Etc.
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References
(1) Anti-proliferative and pro-apoptotic effects from sequenced
combinations of andrographolide and cisplatin on ovarian cancer cell
lines. by Yunos NM, Mutalip SS, Jauri MH, Yu JQ, Huq F.(PubMed)
(2) Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas. by Tung YT, Chen HL, Tsai HC, Yang SH, Chang YC, Chen CM.(PubMed)
(3) Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata. by Rajagopal S, Kumar RA, Deevi DS, Satyanarayana C, Rajagopalan R.(PubMed)
(4) Antifertility effect of Andrographis paniculata (Nees) in male albino rat" by Akbarsha MA, Manivannan B, Hamid KS, Vijayan B., posted in (PubMed)
Food therapy - Asparagus and Immunomodulatory activity
Asparagus
Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.
The immune system is the set of cells and their activity against antigens or infectious agents that comprises of the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Beside foods and nutritional supplements, herbs also play a important role in helping the immune system defend against viruses and bacteria attacks.
Nutrients and chemical constituents
1. Vitamin K
2. Folate
3. Vitamin C
4. Vitamin A
5. Vitamin B Complex
a) Vitamin B1
b) Vitamin B2
c) Vitamin B3
d) Vitamin B6
6. Fiber
7. Manganese
8. Copper
9. Phosphorus
10. Potassium
11. Protein
12. Etc.
Its chemical constituents include essential oils, asparagine, arginine, tyrosine, flavonoids (kaempferol, quercetin, and rutin), resin, and tannin.
The benefits
Immune system plays an important role in defend our body against invasion of foreign invasion. Asparagus racemosus Linn. (Fam. Liliaceae) is considered as an ethno-pharmacologically acclaimed Ayurvedic medicinal plant of which may enhance immune function, according to study aqueous extract of A. racemosus (ARC) showed a dose-related stimulation of NK cell activity with a peak increase of 16.9±4.4% at 5.6 μg/ml. However, ARP demonstrated a higher stimulatory activity of 51.8±1.2% at 25 μg/ml. Other in the study of Asparagus racemosus ameliorates cisplatin induced toxicities and augments its antileishmanial activity by immunomodulation in vivo, A. racemosus in combination with cisplatin not only provided enhanced protective immune response but also resulted in remarkable improved kidney and liver function tests as manifested by normal levels of SGOT, SGPT, alkaline phosphatase, creatinine and urea in blood plasma with normal histological observations as compared to only cisplatin treated L. donovani infected BALB/c mice.
The Side effects
It may cause allergic effects and temporarily smelly urination.
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References
(1) Chemical constituents of Asparagus J. S. Negi, P. Singh, [...], and V. K. Bisht (PubMed)
(2) Characterization and in vitro immunomodulatory screening of fructo-oligosaccharides of Asparagus racemosus Willd. by Thakur M, Connellan P, Deseo MA, Morris C, Praznik W, Loeppert R, Dixit VK.(PubMed)
(3) Asparagus racemosus ameliorates cisplatin induced toxicities and augments its antileishmanial activity by immunomodulation in vivo. by Sachdeva H, Sehgal R, Kaur S.(PubMed)
Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.
The immune system is the set of cells and their activity against antigens or infectious agents that comprises of the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Beside foods and nutritional supplements, herbs also play a important role in helping the immune system defend against viruses and bacteria attacks.
Nutrients and chemical constituents
1. Vitamin K
2. Folate
3. Vitamin C
4. Vitamin A
5. Vitamin B Complex
a) Vitamin B1
b) Vitamin B2
c) Vitamin B3
d) Vitamin B6
6. Fiber
7. Manganese
8. Copper
9. Phosphorus
10. Potassium
11. Protein
12. Etc.
Its chemical constituents include essential oils, asparagine, arginine, tyrosine, flavonoids (kaempferol, quercetin, and rutin), resin, and tannin.
The benefits
Immune system plays an important role in defend our body against invasion of foreign invasion. Asparagus racemosus Linn. (Fam. Liliaceae) is considered as an ethno-pharmacologically acclaimed Ayurvedic medicinal plant of which may enhance immune function, according to study aqueous extract of A. racemosus (ARC) showed a dose-related stimulation of NK cell activity with a peak increase of 16.9±4.4% at 5.6 μg/ml. However, ARP demonstrated a higher stimulatory activity of 51.8±1.2% at 25 μg/ml. Other in the study of Asparagus racemosus ameliorates cisplatin induced toxicities and augments its antileishmanial activity by immunomodulation in vivo, A. racemosus in combination with cisplatin not only provided enhanced protective immune response but also resulted in remarkable improved kidney and liver function tests as manifested by normal levels of SGOT, SGPT, alkaline phosphatase, creatinine and urea in blood plasma with normal histological observations as compared to only cisplatin treated L. donovani infected BALB/c mice.
The Side effects
It may cause allergic effects and temporarily smelly urination.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
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References
(1) Chemical constituents of Asparagus J. S. Negi, P. Singh, [...], and V. K. Bisht (PubMed)
(2) Characterization and in vitro immunomodulatory screening of fructo-oligosaccharides of Asparagus racemosus Willd. by Thakur M, Connellan P, Deseo MA, Morris C, Praznik W, Loeppert R, Dixit VK.(PubMed)
(3) Asparagus racemosus ameliorates cisplatin induced toxicities and augments its antileishmanial activity by immunomodulation in vivo. by Sachdeva H, Sehgal R, Kaur S.(PubMed)
Food therapy - Black beans (Phaseolus) and Antioxidant effects
Black bean is a Small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongs to the family Fabaceae and can bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.
A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with other cell, which in turn, causes oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospho-lipids, DNA and RNA, etc., leading to aging of the organisms, as a result of widespread damage due to set of a chain reaction auto-catalytically after attacking the lipid bilayers of the cell walls.
Nutrients and Chemicals constituents a. Nutrients
1. Carbohydrate
2. Dietary fiber
3. Protein
4. Fat
5. Vitamin A
6. Vitamin B
7. Folate
8. Vitamin C
9. Calcium
10. Magnesium
11. Manganese
12. Phosphorus
13. Molybdenum
14. Iron
10. Etc.
b. Chemicals constituents
The major chemical compounds of black bean include anthocyanin, (-)-epicatechin, delphinidin, petunidin, flavonols and malvidin.
The benefits
Oxidative damage to human body are considered as a major cause of human diseases and aging in some theories. In the study to compare 4 different types of bean with Phenolic extracts of 4 Vigna species of legumes (mung bean, moth bean, and black and red varieties of adzuki beans)showed that Vigna species of legumes are potential source of antioxidant phenolics, Dr. Marathe SA and the research team in the comparison of antioxidative effects of different types of bean found that even though legumes with dark color seed coat did not always possessed high antioxidant activity (e.g. moth bean, black pea, black gram, lentils), but the ntioxidant activity showed positive correlation (r²>0.95) with phenolic contents, in DPPH·, ABTS·⁺ and FRAP assays, whereas poor correlation (r²=0.297) was observed between Fe²⁺ chelating activity of the legumes and phenolic contents.
The Side effect
1. Purines
Black beans contain purines, excessive intake of these substances can cause the accumulation of uric acid, leading to"gout" and kidney stones.
2. Etc.
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Ovarian Cysts And PCOS Elimination
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References (1) Differential accumulation of polyphenolics in black bean genotypes grown in four environments.
Marles MA, Balasubramanian P, Bett KE. (PubMed)
(2) Phenolic antioxidants in some Vigna species of legumes and their distinct inhibitory effects on α-glucosidase and pancreatic lipase activities.
A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with other cell, which in turn, causes oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospho-lipids, DNA and RNA, etc., leading to aging of the organisms, as a result of widespread damage due to set of a chain reaction auto-catalytically after attacking the lipid bilayers of the cell walls.
Nutrients and Chemicals constituents a. Nutrients
1. Carbohydrate
2. Dietary fiber
3. Protein
4. Fat
5. Vitamin A
6. Vitamin B
7. Folate
8. Vitamin C
9. Calcium
10. Magnesium
11. Manganese
12. Phosphorus
13. Molybdenum
14. Iron
10. Etc.
b. Chemicals constituents
The major chemical compounds of black bean include anthocyanin, (-)-epicatechin, delphinidin, petunidin, flavonols and malvidin.
The benefits
Oxidative damage to human body are considered as a major cause of human diseases and aging in some theories. In the study to compare 4 different types of bean with Phenolic extracts of 4 Vigna species of legumes (mung bean, moth bean, and black and red varieties of adzuki beans)showed that Vigna species of legumes are potential source of antioxidant phenolics, Dr. Marathe SA and the research team in the comparison of antioxidative effects of different types of bean found that even though legumes with dark color seed coat did not always possessed high antioxidant activity (e.g. moth bean, black pea, black gram, lentils), but the ntioxidant activity showed positive correlation (r²>0.95) with phenolic contents, in DPPH·, ABTS·⁺ and FRAP assays, whereas poor correlation (r²=0.297) was observed between Fe²⁺ chelating activity of the legumes and phenolic contents.
The Side effect
1. Purines
Black beans contain purines, excessive intake of these substances can cause the accumulation of uric acid, leading to"gout" and kidney stones.
2. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Women health http://kylejnorton.blogspot.ca/p/women-health.html
References (1) Differential accumulation of polyphenolics in black bean genotypes grown in four environments.
Marles MA, Balasubramanian P, Bett KE. (PubMed)
(2) Phenolic antioxidants in some Vigna species of legumes and their distinct inhibitory effects on α-glucosidase and pancreatic lipase activities.
Sreerama YN, Takahashi Y, Yamaki K(PubMed)
(3) Comparative study on antioxidant activity of different varieties of
commonly consumed legumes in India. by Marathe SA, Rajalakshmi V, Jamdar
SN, Sharma A.(PubMed)
Herbal Aloe Vera and Type II Diabetes
Aloe
Vera is species of succulent plant in the genus Aloe, belonging to the
Family Xanthorrhoeaceae, native to Sudan. It has become very popular for
commercial cultivation due to its health benefits. Aloe vera has been
used in herbal medicine in treating many kinds of disease, including
wound, burn healing, minor skin infections, sebaceous cysts, diabetes,
and elevated of cholesterol, etc. It is also one of many popular herb
studied in scientific ways with some conflicted results.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
The benefits
Many herbs have been proven in studies to be effective in treating type II diabetes, including Aloe vera. As a popular herbal remedy in the United Kingdom, oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidaemia. In other study of Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus, Oral administration of PAG for 8 weeks was found to reduce circulating blood glucose concentrations to a normal level in these DIO mice. Its leaf is also found to be useful in treating diabetes, as study said A. vera leaf pulp extract showed hypoglycaemic activity on type I (IDDM) and type II (NIDDM) diabetic rats, the effectiveness being enhanced for type II diabetes in comparison with glibenclamide. On the contrary, A. vera leaf gel extract showed hyperglycaemic activity on NIDDM rats.
The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant, according to the study of "Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study" by Cazzola M, Antivalle M, Sarzi-Puttini P, Dell'Acqua D, Panni B, Caruso I., posted in PubMed
5. Etc.
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Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Women health http://kylejnorton.blogspot.ca/p/women-health.html
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Aloe vera: a systematic review of its clinical effectiveness. by Vogler BK, Ernst E.(PubMed)
(8) Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study(PubMed)
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
The benefits
Many herbs have been proven in studies to be effective in treating type II diabetes, including Aloe vera. As a popular herbal remedy in the United Kingdom, oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidaemia. In other study of Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus, Oral administration of PAG for 8 weeks was found to reduce circulating blood glucose concentrations to a normal level in these DIO mice. Its leaf is also found to be useful in treating diabetes, as study said A. vera leaf pulp extract showed hypoglycaemic activity on type I (IDDM) and type II (NIDDM) diabetic rats, the effectiveness being enhanced for type II diabetes in comparison with glibenclamide. On the contrary, A. vera leaf gel extract showed hyperglycaemic activity on NIDDM rats.
The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant, according to the study of "Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study" by Cazzola M, Antivalle M, Sarzi-Puttini P, Dell'Acqua D, Panni B, Caruso I., posted in PubMed
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Women health http://kylejnorton.blogspot.ca/p/women-health.html
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Aloe vera: a systematic review of its clinical effectiveness. by Vogler BK, Ernst E.(PubMed)
(4) Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. by Kim K, Kim H, Kwon J, Lee S, Kong H, Im SA, Lee YH, Lee YR, Oh ST, Jo TH, Park YI, Lee CK, Kim K.(PubMed)
(5) Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models.
(7) Oral aloe vera-induced hepatitis(PubMed)(8) Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study(PubMed)
CV health starts with good nutrition
A healthy diet is essential, regardless of CV risk. Caloric balance is inherent to a good diet.
Despite patients who say they eat little, ideal weight can be
maintained if calories are burned. Composition is another component of a
healthy diet. Dr. Whayne TF Jr, and Dr. Maulik N. at the University of Kentucky, showed that Exercise, in conjunction with a healthy diet
and good nutrition, helps maintain optimal weight and provides CV
benefit such as decreased inflammation and increased vasodilatation.
Whether vitamins or other nutritional supplements are important in a healthy diet is unproven. Nevertheless, the most promising data of added benefit to a healthy diet
is with vitamin D. Some dietary supplements also have promise. Alcohol,
in moderation, especially red wine, has nutritional and heart
protective benefits. Antioxidants, endogenous or exogenous, have
received increased interest and appear to play a favorable nutritional
role. CV health starts with good nutrition(1).
Chinese Secrets To Fatty Liver And Obesity Reversal
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Optimal Health And Loose Weight
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(1) " Nutrition and the healthy heart with an exercise boost" by Whayne TF Jr, Maulik N.
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(1) " Nutrition and the healthy heart with an exercise boost" by Whayne TF Jr, Maulik N.
Obesity and type 2 diabetes (T2DM) and level of lysophosphatidylcholine (LPC)
In the investigation of the plasma lipidomic analysis in a rodent model of obesity and insulin resistance as well as in lean, obese and obese individuals with T2DM, showed that Irrespective of species, our lipidomic profiling revealed a generalized decrease in circulating LPC species in states of obesity. Moreover, our data indicate that diet and adiposity, rather than insulin resistance or diabetes per se, play an important role in altering the plasma LPC profile(1).
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(1) "Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes"by Barber MN, Risis S, Yang C, Meikle PJ, Staples M, Febbraio MA, Bruce CR.
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