Kyle J. Norton
Skin is a large organ that protects our internal organs and tissues by shielding them from the invasion of foreign pathogens. Several different components, such as water, protein, lipids, and different minerals and chemicals have been found to make up the skin integrity.
Furthermore, the skin accompanied by the liver and kidney forms a detoxed triad by eliminating toxins from the body.
Skin regeneration or repair is a natural process which epithelial cells restore the epidermis once the dermis has been regenerated.
However, in major injuries, the repair mechanisms may not completely restore the skin to its original condition, leading to the formation of scars.
In details, the skin regenerates through 3 stages
* Initial phase or acute phase of infection.
The immune system's white blood cells of the first line of defense stimulate the blood platelets to cover the wound or injury and production of proinflammatory cytokines, leading to the creation of new blood vessels to replace those that were damaged in the precipitating incident.
* Regeneration of the epidermis and dermis involved in the proliferation of the cells of the stratum basale and the movement of a healthy portion of the dermis at the edges of the wound into its interior.
Any disruption of the process of skin regeneration can lead to the formation of scars
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound for the treatment of skin wounds, researchers examined the effect of curcumin the main constituent found in turmeric on free radical scavenging and anti-inflammation activity.
During the experiment, curcumin was found to modulate the phase II detoxification enzymes associated with detoxification reactions and the protection against oxidative stress.
Furthermore, the injection of curcumin also enhanced skin regeneration and wound healing.
Moreover, curcumin protects the skin by quenching free radicals and reducing inflammation involved in protein that stimulates the production of inflammatory cytokines.
Curcumin administration also promotes skin regeneration in wound healing by improving wound-healing time, collagen deposition, and increased fibroblast and vascular density in wounds.
Additionally, the effects of skin regeneration and wound healing were also attributed to the compound's proangiogenic property.
Based on the findings, researchers said, "These studies suggest the beneficial effects of curcumin and the potential of this compound to be developed as a potent nontoxic agent for treating skin diseases".
Taken altogether, turmeric processed with a high amount of curcumin may be considered a supplement for the enhancement of skin regeneration in wound healing, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Skin regenerative potentials of curcumin by Thangapazham RL1, Sharad S, Maheshwari RK. (PubMed)
(2) Beneficial role of curcumin in skin diseases by Thangapazham RL1, Sharma A, Maheshwari RK. (PubMed)
Thursday, 2 November 2023
#Phytochemical #AnacardicAcid Processes Anti Breast Cancer Activity, Researchers Say
Kyle J. Norton
Anacardic acids, a phytochemical found abundantly in the may process a potential effect in reducing the risk and treatment of breast cancer, some scientists suggested.
Breast cancer is a chronic condition associated with irregular cell growth caused by the alternation of DNA of breast cells.
Most cases of breast cancer start on the cells on the surface of the inner lining tissue of the milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
However, after colonizing most of the breast tissue, the cancer cell at a later stage can travel a distance away to infect other healthy tissue and organs through the circulation of lymph and blood.
According to the statistics, every year, 75,000 and 234,000 patients are diagnosed with breast cancer (BC) in Germany and in the USA, respectively.
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
Although genetic preposition such as mutated genes BRCA 1 and 2 are the best-known risk factors associated with the 60% increased risk of breast cancer.
An unhealthy lifestyle including poor diet and physical inactivity is also the most mentioned risk factor by scientists.
Dr. Max Dieterich, the lead scientist in the study "Influence of Lifestyle Factors on Breast Cancer Risk" wrote, "Epidemiological studies that lifestyle factors play an important role in the development of BC. For example, daughters of Asian women who have migrated to the USA revealed an increased risk of developing BC, which was attributed to the exposure to a different lifestyle and nutritional factors".
These results suggested regardless of ethical origin, if you follow the Western diet and lifestyle, you are at higher levels of risk, compared to those who follow the traditional diet.
More precisely, if you are following a diet high in saturated and trans fat, red meat, and processed food, regardless of where you're from, you are at a higher risk of breast cancer.
Therefore modifying the lifestyle risk factors to develop a strategy for BC prevention is an urgency for the prevention of breast cancer.
Other risk factors associated with breast cancer are age, family history of BC, personal breast history (pre-malignant lesions), breast density, thorax radiation, and several menstrual cycles during the lifetime.
To understand the effect of Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid), a dietary and medicinal phytochemical anticancer activity in cell and animal models, researchers at the cancer team program at the University of Louisville School of Medicine, conducted an experiment to test the mechanisms of the AnAc in the inhibition of breast cancer cell proliferation.
Application of the AnAc 24:1(omega5) purified from geranium (Pelargonium x hortorum) inhibited the proliferation of estrogen receptor alpha (ERalpha)-positive MCF-7 and endocrine-resistant LCC9 and LY2 breast cancer cells with greater efficacy than ERalpha-negative primary human breast epithelial cells, MCF-10A normal breast epithelial cells, and MDA-MB-231 basal-like breast cancer cells.
AnAc 24:1(omega5) inhibited cell cycle progression and induced apoptosis in a cell-specific manner.
AnAc 24:1(omega5) inhibited the breast cancer cell line and was attributed to the stimulation of proteins that are responsible for program cell death and anti-cell proliferation.
.
Dr. Schultz DJ, the lead scientist at the end of the study said, "These data indicate that AnAc 24:1(omega5) inhibits cell proliferation, cell cycle progression, and apoptosis in an ER-dependent manner by reducing ER-DNA interaction and inhibiting ER-mediated transcriptional responses".
Furthermore, in examining the series of N-(4-cyano-3-trifluoromethylphenyl)-2-ethoxy-6-alkyl (and alkenyl) benzamides related to the anacardic acid derivative CTPB prepared from 2,6-dihydroxybenzoic acid, researchers found that In U937 cells
* Derivatives labeled 7 c, 7 d, 7, and 7 j exerted a potential effect in inducing cell-cycle arrest in the G1 phase,
* The derivative also causes apoptosis in about 20 % of the cells and increases the acetylation of H3. Loss of acylation levels of H3 was associated with patients with breast cancer.
Taken together, Anacardic acids may be considered a functional phytochemical for the prevention and an adjunct therapy combined with the primary medicine for the treatment of breast cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation by Schultz DJ, Wickramasinghe NS, Ivanova MM, Isaacs SM, Dougherty SM, Imbert-Fernandez Y, Cunningham AR, Chen C, Klinge CM. (PubMed)
(2) New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators.
Souto JA, Benedetti R, Otto K, Miceli M, Alvarez R, Altucci L, de Lera AR.(PubMed)
Anacardic acids, a phytochemical found abundantly in the may process a potential effect in reducing the risk and treatment of breast cancer, some scientists suggested.
Breast cancer is a chronic condition associated with irregular cell growth caused by the alternation of DNA of breast cells.
Most cases of breast cancer start on the cells on the surface of the inner lining tissue of the milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
However, after colonizing most of the breast tissue, the cancer cell at a later stage can travel a distance away to infect other healthy tissue and organs through the circulation of lymph and blood.
According to the statistics, every year, 75,000 and 234,000 patients are diagnosed with breast cancer (BC) in Germany and in the USA, respectively.
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
Although genetic preposition such as mutated genes BRCA 1 and 2 are the best-known risk factors associated with the 60% increased risk of breast cancer.
An unhealthy lifestyle including poor diet and physical inactivity is also the most mentioned risk factor by scientists.
Dr. Max Dieterich, the lead scientist in the study "Influence of Lifestyle Factors on Breast Cancer Risk" wrote, "Epidemiological studies that lifestyle factors play an important role in the development of BC. For example, daughters of Asian women who have migrated to the USA revealed an increased risk of developing BC, which was attributed to the exposure to a different lifestyle and nutritional factors".
These results suggested regardless of ethical origin, if you follow the Western diet and lifestyle, you are at higher levels of risk, compared to those who follow the traditional diet.
More precisely, if you are following a diet high in saturated and trans fat, red meat, and processed food, regardless of where you're from, you are at a higher risk of breast cancer.
Therefore modifying the lifestyle risk factors to develop a strategy for BC prevention is an urgency for the prevention of breast cancer.
Other risk factors associated with breast cancer are age, family history of BC, personal breast history (pre-malignant lesions), breast density, thorax radiation, and several menstrual cycles during the lifetime.
To understand the effect of Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid), a dietary and medicinal phytochemical anticancer activity in cell and animal models, researchers at the cancer team program at the University of Louisville School of Medicine, conducted an experiment to test the mechanisms of the AnAc in the inhibition of breast cancer cell proliferation.
Application of the AnAc 24:1(omega5) purified from geranium (Pelargonium x hortorum) inhibited the proliferation of estrogen receptor alpha (ERalpha)-positive MCF-7 and endocrine-resistant LCC9 and LY2 breast cancer cells with greater efficacy than ERalpha-negative primary human breast epithelial cells, MCF-10A normal breast epithelial cells, and MDA-MB-231 basal-like breast cancer cells.
AnAc 24:1(omega5) inhibited cell cycle progression and induced apoptosis in a cell-specific manner.
AnAc 24:1(omega5) inhibited the breast cancer cell line and was attributed to the stimulation of proteins that are responsible for program cell death and anti-cell proliferation.
.
Dr. Schultz DJ, the lead scientist at the end of the study said, "These data indicate that AnAc 24:1(omega5) inhibits cell proliferation, cell cycle progression, and apoptosis in an ER-dependent manner by reducing ER-DNA interaction and inhibiting ER-mediated transcriptional responses".
Furthermore, in examining the series of N-(4-cyano-3-trifluoromethylphenyl)-2-ethoxy-6-alkyl (and alkenyl) benzamides related to the anacardic acid derivative CTPB prepared from 2,6-dihydroxybenzoic acid, researchers found that In U937 cells
* Derivatives labeled 7 c, 7 d, 7, and 7 j exerted a potential effect in inducing cell-cycle arrest in the G1 phase,
* The derivative also causes apoptosis in about 20 % of the cells and increases the acetylation of H3. Loss of acylation levels of H3 was associated with patients with breast cancer.
Taken together, Anacardic acids may be considered a functional phytochemical for the prevention and an adjunct therapy combined with the primary medicine for the treatment of breast cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation by Schultz DJ, Wickramasinghe NS, Ivanova MM, Isaacs SM, Dougherty SM, Imbert-Fernandez Y, Cunningham AR, Chen C, Klinge CM. (PubMed)
(2) New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators.
Souto JA, Benedetti R, Otto K, Miceli M, Alvarez R, Altucci L, de Lera AR.(PubMed)
#Honey Exerts Anti #ProstateCancer by Inducing Cell Cytotoxicity, Researchers Suggest
Kyle J. Norton
Honey may be a potential natural source for the pharmaceutic target for the finding of anti-prostate cancer single and synthetic medicine, some studies suggested. Prostate cancer is a low-growth and progression medical and chronic disease caused by cell growth disorderly and irregularly in the prostate tissue.
Most cases of primary prostate cancer start in the cells on the surface of the prostate's inner lining tissue. Most people with the early stage of prostate cancer may not have any symptoms, however, some may experience the symptoms of the enlarged prostate such as pain during urination and urinary difficulty.
Most secondary cancers associated with prostate cancer metastasis are the lymph nodes and the bones.
However, at the advanced stage, the cancerous cells in the prostate can travel a distance away to infect other healthy tissues and organs by way of the lymph system or bloodstream.
Most prostate cancer is diagnosed during the annual physical exam after the enlarged prostate is discovered
Researchers do not the exact cause of prostate cancer. Neither do they know why men in the same family with similar diet patterns, some are susceptible to the prostate cell's DNA alternation, while some do not.
According to the statistics provided by the Australian government, the mortality rate of prostate cancer decreased from 34 deaths per 100,000 males in 1982 to 31 per 100,000.
In 2011. Around 9 in 10 males diagnosed with prostate cancer survive 5 years from diagnosis. Prostate cancer is the fourth leading cause of mortality among Australian males, causing 3,294 deaths.
There are many risk factors associated with the development of prostate cancer. However, An unhealthy diet and lifestyle are the preventable risk factors that cause widespread prostate cancer in the Western world.
Dr. Roberto Fabian, the lead scientist at the University of Perugia, in the support that the Western diet is the major cause of prostate cancer, conducted the study "A Western Dietary Pattern Increases Prostate Cancer Risk: A Systematic Review and Meta-Analysis" by searching the database of PubMed, Web of Science to identify studies reporting the relationship between dietary patterns and PC risk.
After taking the account multivariable-adjusted odds ratios (ORs), wrote, " Twelve observational studies were included in the meta-analysis which identified a “Healthy pattern” and a “Western pattern” and "The Healthy pattern was not related to PC risk (OR = 0.96; 95% confidence interval (CI): 0.88–1.04) while the Western pattern significantly increased it (OR = 1.34; 95% CI: 1.08–1.65)".
These comparable results once again suggested that men who follow the Western diet are associated with an increased risk of prostate cancer
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
Honey is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient for the treatment of prostate cancer without inducing any side effects, researchers at the University of Otago looked into honey, the complex biological substance, consisting mainly of sugars, phenolic compounds, and enzymes.
In prostate cancer cells PC3 and DU145, the application of honey whole food exerted a strong inhibitory effect through the expression of cytotoxicity.
The sulforhodamine B assay gave valid anti-prostate cancer results, but measures only protein content, providing no information about cell death in the remaining cells.
The trypan blue assay and a microscope-based propidium iodide/Hoechst staining assay assess only late-stage membrane permeability.
Only the propidium iodide/Hoechst assay provides morphological information about the cell death mechanism.
These results suggested that honey processed a potential to induce prostate cancer cell death through certain known and unknown mechanisms besides those found in the sulforhodamine B and propidium iodide/Hoechst assays
Interestingly, they examine the possibility of New Zealand thyme, manuka, and honeydew honey, and their major sugar and phenolic components, reducing the development of metastatic cancer.also in PC3 and DU145 prostate cancer cell lines. researchers showed that
Non-toxic concentrations of thyme and honeydew honey reduced prostate cancer cell migration by 20% observed by the Boyden chamber-based migration assay,
All phenolic compounds including gallic acid, quercetin, kaempferol, and chrysin except caffeic acid also lowered migration, although a mixture of only the sugars found in honey had no effect.
All of the honey, phenolics, and sugar-only mixture reduced the invasive movement of cells through the extracellular matrix in the cellular division by up to 75%.
Additional analysis also found that each of the three kinds of honey and the sugar-only mixture reduces cell adhesion to collagen I by 90%, except for quercetin.
However, honey and its sugar and phenolic components can lower the metastatic properties of cancer cells and may do this by preventing effective cell adhesion to the extracellular matrix.
Once again, researchers suggested that the sugars and phenol compounds of honey are much more effective in combination than individually.
In other words, the anticancer activity of honey is attributed to all ingredients in the whole food.
Taken together, intake of honey in a moderate amount daily may have a potential effect in the prevention and combined with primary therapy for the treatment of prostate cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay by Abel SDA1, Baird SK. (PubMed)
(2) Honey reduces the metastatic characteristics of prostate cancer cell lines by promoting a loss of adhesion by Abel SDA1, Dadhwal S2, Gamble AB2, Baird SK. (PubMed)
(3) A Western Dietary Pattern Increases Prostate Cancer Risk: A Systematic Review and Meta-Analysis by Roberto Fabiani,1,* Liliana Minelli,2 Gaia Bertarelli,3 and Silvia Bacci. (PubMed)
Honey may be a potential natural source for the pharmaceutic target for the finding of anti-prostate cancer single and synthetic medicine, some studies suggested. Prostate cancer is a low-growth and progression medical and chronic disease caused by cell growth disorderly and irregularly in the prostate tissue.
Most cases of primary prostate cancer start in the cells on the surface of the prostate's inner lining tissue. Most people with the early stage of prostate cancer may not have any symptoms, however, some may experience the symptoms of the enlarged prostate such as pain during urination and urinary difficulty.
Most secondary cancers associated with prostate cancer metastasis are the lymph nodes and the bones.
However, at the advanced stage, the cancerous cells in the prostate can travel a distance away to infect other healthy tissues and organs by way of the lymph system or bloodstream.
Most prostate cancer is diagnosed during the annual physical exam after the enlarged prostate is discovered
Researchers do not the exact cause of prostate cancer. Neither do they know why men in the same family with similar diet patterns, some are susceptible to the prostate cell's DNA alternation, while some do not.
According to the statistics provided by the Australian government, the mortality rate of prostate cancer decreased from 34 deaths per 100,000 males in 1982 to 31 per 100,000.
In 2011. Around 9 in 10 males diagnosed with prostate cancer survive 5 years from diagnosis. Prostate cancer is the fourth leading cause of mortality among Australian males, causing 3,294 deaths.
There are many risk factors associated with the development of prostate cancer. However, An unhealthy diet and lifestyle are the preventable risk factors that cause widespread prostate cancer in the Western world.
Dr. Roberto Fabian, the lead scientist at the University of Perugia, in the support that the Western diet is the major cause of prostate cancer, conducted the study "A Western Dietary Pattern Increases Prostate Cancer Risk: A Systematic Review and Meta-Analysis" by searching the database of PubMed, Web of Science to identify studies reporting the relationship between dietary patterns and PC risk.
After taking the account multivariable-adjusted odds ratios (ORs), wrote, " Twelve observational studies were included in the meta-analysis which identified a “Healthy pattern” and a “Western pattern” and "The Healthy pattern was not related to PC risk (OR = 0.96; 95% confidence interval (CI): 0.88–1.04) while the Western pattern significantly increased it (OR = 1.34; 95% CI: 1.08–1.65)".
These comparable results once again suggested that men who follow the Western diet are associated with an increased risk of prostate cancer
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
Honey is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient for the treatment of prostate cancer without inducing any side effects, researchers at the University of Otago looked into honey, the complex biological substance, consisting mainly of sugars, phenolic compounds, and enzymes.
In prostate cancer cells PC3 and DU145, the application of honey whole food exerted a strong inhibitory effect through the expression of cytotoxicity.
The sulforhodamine B assay gave valid anti-prostate cancer results, but measures only protein content, providing no information about cell death in the remaining cells.
The trypan blue assay and a microscope-based propidium iodide/Hoechst staining assay assess only late-stage membrane permeability.
Only the propidium iodide/Hoechst assay provides morphological information about the cell death mechanism.
These results suggested that honey processed a potential to induce prostate cancer cell death through certain known and unknown mechanisms besides those found in the sulforhodamine B and propidium iodide/Hoechst assays
Interestingly, they examine the possibility of New Zealand thyme, manuka, and honeydew honey, and their major sugar and phenolic components, reducing the development of metastatic cancer.also in PC3 and DU145 prostate cancer cell lines. researchers showed that
Non-toxic concentrations of thyme and honeydew honey reduced prostate cancer cell migration by 20% observed by the Boyden chamber-based migration assay,
All phenolic compounds including gallic acid, quercetin, kaempferol, and chrysin except caffeic acid also lowered migration, although a mixture of only the sugars found in honey had no effect.
All of the honey, phenolics, and sugar-only mixture reduced the invasive movement of cells through the extracellular matrix in the cellular division by up to 75%.
Additional analysis also found that each of the three kinds of honey and the sugar-only mixture reduces cell adhesion to collagen I by 90%, except for quercetin.
However, honey and its sugar and phenolic components can lower the metastatic properties of cancer cells and may do this by preventing effective cell adhesion to the extracellular matrix.
Once again, researchers suggested that the sugars and phenol compounds of honey are much more effective in combination than individually.
In other words, the anticancer activity of honey is attributed to all ingredients in the whole food.
Taken together, intake of honey in a moderate amount daily may have a potential effect in the prevention and combined with primary therapy for the treatment of prostate cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay by Abel SDA1, Baird SK. (PubMed)
(2) Honey reduces the metastatic characteristics of prostate cancer cell lines by promoting a loss of adhesion by Abel SDA1, Dadhwal S2, Gamble AB2, Baird SK. (PubMed)
(3) A Western Dietary Pattern Increases Prostate Cancer Risk: A Systematic Review and Meta-Analysis by Roberto Fabiani,1,* Liliana Minelli,2 Gaia Bertarelli,3 and Silvia Bacci. (PubMed)
#Phytochemical #Allicin Inhibits #CardiovascularDiseases by Inducing Vasorelaxation and Alleviating Various Pathological Conditions, Scientists Find
Kyle J. Norton
Allicin, a bioactive compound found abundantly in garlic and onion may be the next pharmaceutical target to identify the single-ingredient medicine for the treatment of cardiovascular disease, some scientists suggested.
Cardiovascular diseases are a class of chronic and medical conditions of heart and blood vessel disease related to the plaque build-up in the walls of the arteries that cause the blockage of blood flow and reduce the oxygen and nutrients rich blood reaching the heart, leading to heart attack and stroke,
There are many causes of heart disease. Most heart diseases are caused by high blood pressure that contributes to the hardening of the arteries.
High levels of bad cholesterol (LDL) build up in the arteries as a result of an uncontrolled diet with high levels of saturated fat and trans fat.
All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
Dr. P. Scarborough, the lead author in the study "An index of an unhealthy lifestyle is associated with coronary heart disease mortality rates for small areas in England after adjustment for deprivation" wrote, "Sets of synthetic estimates of the ward-level prevalence of low fruit and vegetable consumption, obesity, raised blood pressure, raised cholesterol and smoking were combined to develop an index of an unhealthy lifestyle".
These results suggested that people who follow the Western diet with high consumption of saturated and trans fat, red meats, and processed food accompanied by physical inactivity are associated with a substantially increased risk of cardiovascular disease.
On the other hand, people who are nonsmokers and follow a traditional diet with a high intake of fruits and vegetables and whole-grain and daily moderate exercise have a lower risk of the disease onset.
If you experience symptoms of chest pain, tightness, chest discomfort (angina), shortness of breath and weakness or coldness in your legs or arms, please check with your doctor immediately, you may be at the early onset of cardiovascular disease.
Allicin is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
In the concerns of hyperlipidemia. cause of cardiovascular disease, researchers at the Taishan Medical University, conducted an investigation to test the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats.
In the study, healthy male Wistar rats fed a high-fat diet were treated with fenofibrate (80 mg/kg per day) alone, allicin (60 mg/kg per day) alone, and a lower dosage of combined therapy (allicin 20 mg/kg per day and fenofibrate 30 mg/kg per day) respectively for 8 weeks.
At the final phase, compared with high-fat diet control, fenofibrate alone or the combined therapy increased remarkably the levels of high-density lipoprotein respectively (P<0.05).
Both single and combined therapy of fenofibrate and allicin significantly enhanced the levels of NO (P<0.01 or P<0.05), but the combined therapy had the greatest high endothelial-dependent vascular relaxation (EDVR) responses. These suggested that both ingredients had a significant effect in enhancing vascular relaxation.
Futhermore, the combined therapy also inhibited the levels of ALT and AST caused by infection of a high-fat diet in the stimulation of oxidative stress.
Additionally, in the search for chemicals that arise from natural food sources with the potential to provide beneficial effects on the cardiovascular system, researchers at the heart team at The Hong Kong Polytechnic University launched a study to test the effect of allicin on heart diseases.
Application of Allicin demonstrated cardioprotective effects by inducing vasorelaxation and alleviating various pathological conditions of CVD, including cardiac hypertrophy, angiogenesis, platelet aggregation, hyperlipidemia, and hyperglycemia.
Allicin was also discovered to further protect the cardiovascular system by enhancing the antioxidant status by lowering the level of reactive oxygen species and stimulating the production of glutathione.
Dr. Chan JY, the lead author, said, "From the pharmacokinetic studies, allicin is known to be hydrophobic and can be readily absorbed through the cell membrane without inducing any damage to the phospholipid bilayer and then rapidly metabolized to exert pharmacological effects that are important to the cardiovascular system".
Taken all together, Allicin, the bioactive compound may be considered a functional supplement for the prevention and treatment of cardiovascular diseases, depending on the further differentiation in the human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(3) The effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats BY Li W, Wang D, Song G, Zuo C, Qiao X, Qin S.(PubMed)
(4) A review of the cardiovascular benefits and antioxidant properties of allicin by Chan JY, Yuen AC, Chan RY, Chan SW.(PubMed)
(5) An index of unhealthy lifestyle is associated with coronary heart disease mortality rates for small areas in England after adjustment for deprivation by P. Scarborough,⁎ S. Allender, M. Rayner, and M. Goldacre. (PMC)
Allicin, a bioactive compound found abundantly in garlic and onion may be the next pharmaceutical target to identify the single-ingredient medicine for the treatment of cardiovascular disease, some scientists suggested.
Cardiovascular diseases are a class of chronic and medical conditions of heart and blood vessel disease related to the plaque build-up in the walls of the arteries that cause the blockage of blood flow and reduce the oxygen and nutrients rich blood reaching the heart, leading to heart attack and stroke,
There are many causes of heart disease. Most heart diseases are caused by high blood pressure that contributes to the hardening of the arteries.
High levels of bad cholesterol (LDL) build up in the arteries as a result of an uncontrolled diet with high levels of saturated fat and trans fat.
All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
Dr. P. Scarborough, the lead author in the study "An index of an unhealthy lifestyle is associated with coronary heart disease mortality rates for small areas in England after adjustment for deprivation" wrote, "Sets of synthetic estimates of the ward-level prevalence of low fruit and vegetable consumption, obesity, raised blood pressure, raised cholesterol and smoking were combined to develop an index of an unhealthy lifestyle".
These results suggested that people who follow the Western diet with high consumption of saturated and trans fat, red meats, and processed food accompanied by physical inactivity are associated with a substantially increased risk of cardiovascular disease.
On the other hand, people who are nonsmokers and follow a traditional diet with a high intake of fruits and vegetables and whole-grain and daily moderate exercise have a lower risk of the disease onset.
If you experience symptoms of chest pain, tightness, chest discomfort (angina), shortness of breath and weakness or coldness in your legs or arms, please check with your doctor immediately, you may be at the early onset of cardiovascular disease.
Allicin is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
In the concerns of hyperlipidemia. cause of cardiovascular disease, researchers at the Taishan Medical University, conducted an investigation to test the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats.
In the study, healthy male Wistar rats fed a high-fat diet were treated with fenofibrate (80 mg/kg per day) alone, allicin (60 mg/kg per day) alone, and a lower dosage of combined therapy (allicin 20 mg/kg per day and fenofibrate 30 mg/kg per day) respectively for 8 weeks.
At the final phase, compared with high-fat diet control, fenofibrate alone or the combined therapy increased remarkably the levels of high-density lipoprotein respectively (P<0.05).
Both single and combined therapy of fenofibrate and allicin significantly enhanced the levels of NO (P<0.01 or P<0.05), but the combined therapy had the greatest high endothelial-dependent vascular relaxation (EDVR) responses. These suggested that both ingredients had a significant effect in enhancing vascular relaxation.
Futhermore, the combined therapy also inhibited the levels of ALT and AST caused by infection of a high-fat diet in the stimulation of oxidative stress.
Additionally, in the search for chemicals that arise from natural food sources with the potential to provide beneficial effects on the cardiovascular system, researchers at the heart team at The Hong Kong Polytechnic University launched a study to test the effect of allicin on heart diseases.
Application of Allicin demonstrated cardioprotective effects by inducing vasorelaxation and alleviating various pathological conditions of CVD, including cardiac hypertrophy, angiogenesis, platelet aggregation, hyperlipidemia, and hyperglycemia.
Allicin was also discovered to further protect the cardiovascular system by enhancing the antioxidant status by lowering the level of reactive oxygen species and stimulating the production of glutathione.
Dr. Chan JY, the lead author, said, "From the pharmacokinetic studies, allicin is known to be hydrophobic and can be readily absorbed through the cell membrane without inducing any damage to the phospholipid bilayer and then rapidly metabolized to exert pharmacological effects that are important to the cardiovascular system".
Taken all together, Allicin, the bioactive compound may be considered a functional supplement for the prevention and treatment of cardiovascular diseases, depending on the further differentiation in the human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(3) The effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats BY Li W, Wang D, Song G, Zuo C, Qiao X, Qin S.(PubMed)
(4) A review of the cardiovascular benefits and antioxidant properties of allicin by Chan JY, Yuen AC, Chan RY, Chan SW.(PubMed)
(5) An index of unhealthy lifestyle is associated with coronary heart disease mortality rates for small areas in England after adjustment for deprivation by P. Scarborough,⁎ S. Allender, M. Rayner, and M. Goldacre. (PMC)
#Aqueous #Broccoli #Extracts (BEs) Protect the Pancreatic Tissue Damage in Diabetes, Researchers Suggest
Kyle J. Norton
Oxidative stress is a condition characterized by a chain reaction of the overexpression of free radicals that cannot be stopped.
In other words, overexpression of free radicals and depletion of antioxidants are the major causes of oxidative stress.
More precisely, oxidative stress is a result of a long-term imbalance of the ratio of free radicals and antioxidants produced by the host.
Free radicals are highly reactive atoms with a single unpaired electron in an outermost shell with a function to donate or intercept an electron from other stable atoms, leading to a chain reaction that induces oxidative damage to the enzymes, other proteins, unsaturated fatty acid, phospholipids, DNA and RNA,..,
Antioxidants are stable atoms that inhibit oxidation.
Oxidative stress may be preventable if antioxidants in the body can pair all electrons in the outermost ring.
Overexpression of free radicals is harmful to the human body. However, free radicals in a moderate amount generated from cell metabolism may play a critical role in the synthesis of energy and essential molecules and boost the immune system.
In a healthy individual, antioxidants produced by the body are good enough to prevent the onset of oxidative stress. However, in people with a weakened immune system, intake of dietary antioxidants such as supplements of antioxidant-rich food may be necessary.
Dr. Biller-Takahashi JD, the lead scientist in the joint study led by the UNESP Univ Estadual Paulista wrote, "Short-term supplementation with 0.6 mg Se-yeast kg(-1) reestablished the antioxidative status, allowing the production of innate components which can boost immunity without the risk of oxidative stress".
Broccoli is a species of Brassica Oleracea, belonging to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
In findings of a potent and natural compound to prevent pancreatic tissue damage in diabetes, scientists investigated the potential hypoglycaemic and antioxidant properties of aqueous broccoli extracts (BEs) in diabetic rats.
Rats selected for the study induced diabetes by a single intraperitoneal injection dose of 50 mg/kg body weight of Streptozotocin (STZ) drug were co-administration with or without BEs.
After 8 weeks, based on the blood analysis, diabetic rats without co-administration with BEs showed significantly higher levels of pancreatic cell DNA damage, depletion of levels of antioxidant GSH, and impaired antioxidant capacity (TAC) levels, compared to non-diabetics.
Furthermore, diabetes rats without co-administration with BEs also demonstrated significant pancreatic tissue damage.
Diabetes rats with BEs co-administration not only reduced all parameters expression but also protected the pancreatic tissue against histopathological changes.
In other words, BEs reduced the damage to pancreas tissue caused by STZ-induced hyperglycemia and oxidative injury by enhancing the production of antioxidant enzymes in the tested rats.
Based on the findings, researchers said, "The used in vivo model confirmed the efficacy of BE as an anti-diabetic herbal medicine and provided insights into the capacity of BE to be used for phytoremediation purposes for human type 2 diabetes".
Taken together, broccoli may be considered a functional food for the prevention of oxidative stress-induced pancreatic tissue damage, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli (Brassica oleracea) Reduces Oxidative Damage to Pancreatic Tissue and Combats Hyperglycaemia in Diabetic Rats by Suresh S1, Waly MI1, Rahman MS1, Guizani N1, Al-Kindi MAB2, Al-Issaei HKA2, Al-Maskari SNM3, Al-Ruqaishi BRS3, Al-Salami A. (PubMed)
(2) The immune system is limited by oxidative stress: Dietary selenium promotes optimal antioxidative status and greatest immune defense in pacu Piaractus mesopotamicus by Biller-Takahashi JD1, Takahashi LS2, Mingatto FE3, Urbinati EC. (PubMed)
Oxidative stress is a condition characterized by a chain reaction of the overexpression of free radicals that cannot be stopped.
In other words, overexpression of free radicals and depletion of antioxidants are the major causes of oxidative stress.
More precisely, oxidative stress is a result of a long-term imbalance of the ratio of free radicals and antioxidants produced by the host.
Free radicals are highly reactive atoms with a single unpaired electron in an outermost shell with a function to donate or intercept an electron from other stable atoms, leading to a chain reaction that induces oxidative damage to the enzymes, other proteins, unsaturated fatty acid, phospholipids, DNA and RNA,..,
Antioxidants are stable atoms that inhibit oxidation.
Oxidative stress may be preventable if antioxidants in the body can pair all electrons in the outermost ring.
Overexpression of free radicals is harmful to the human body. However, free radicals in a moderate amount generated from cell metabolism may play a critical role in the synthesis of energy and essential molecules and boost the immune system.
In a healthy individual, antioxidants produced by the body are good enough to prevent the onset of oxidative stress. However, in people with a weakened immune system, intake of dietary antioxidants such as supplements of antioxidant-rich food may be necessary.
Dr. Biller-Takahashi JD, the lead scientist in the joint study led by the UNESP Univ Estadual Paulista wrote, "Short-term supplementation with 0.6 mg Se-yeast kg(-1) reestablished the antioxidative status, allowing the production of innate components which can boost immunity without the risk of oxidative stress".
Broccoli is a species of Brassica Oleracea, belonging to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
In findings of a potent and natural compound to prevent pancreatic tissue damage in diabetes, scientists investigated the potential hypoglycaemic and antioxidant properties of aqueous broccoli extracts (BEs) in diabetic rats.
Rats selected for the study induced diabetes by a single intraperitoneal injection dose of 50 mg/kg body weight of Streptozotocin (STZ) drug were co-administration with or without BEs.
After 8 weeks, based on the blood analysis, diabetic rats without co-administration with BEs showed significantly higher levels of pancreatic cell DNA damage, depletion of levels of antioxidant GSH, and impaired antioxidant capacity (TAC) levels, compared to non-diabetics.
Furthermore, diabetes rats without co-administration with BEs also demonstrated significant pancreatic tissue damage.
Diabetes rats with BEs co-administration not only reduced all parameters expression but also protected the pancreatic tissue against histopathological changes.
In other words, BEs reduced the damage to pancreas tissue caused by STZ-induced hyperglycemia and oxidative injury by enhancing the production of antioxidant enzymes in the tested rats.
Based on the findings, researchers said, "The used in vivo model confirmed the efficacy of BE as an anti-diabetic herbal medicine and provided insights into the capacity of BE to be used for phytoremediation purposes for human type 2 diabetes".
Taken together, broccoli may be considered a functional food for the prevention of oxidative stress-induced pancreatic tissue damage, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli (Brassica oleracea) Reduces Oxidative Damage to Pancreatic Tissue and Combats Hyperglycaemia in Diabetic Rats by Suresh S1, Waly MI1, Rahman MS1, Guizani N1, Al-Kindi MAB2, Al-Issaei HKA2, Al-Maskari SNM3, Al-Ruqaishi BRS3, Al-Salami A. (PubMed)
(2) The immune system is limited by oxidative stress: Dietary selenium promotes optimal antioxidative status and greatest immune defense in pacu Piaractus mesopotamicus by Biller-Takahashi JD1, Takahashi LS2, Mingatto FE3, Urbinati EC. (PubMed)
#Bromelain Enzyme B2252 Show a Strong Inhibition of Influenza A(H1N1) and B Viruses, According to Studies
Kyle J. Norton
Influenza A, B, C, and D are 4 types of flu influenza. Influenza virus A and B are seasonal flu that occur during the fall, winter, and early spring, They cause sniffling, aching, coughing, running and stuffy nose, and fever, affecting over 20% of the general population.
Influenza virus type C in the virus family Orthomyxoviridae tends to cause mild upper respiratory infections, similar to those of cold.
Influenza D viruses only affect cattle.
Individuals who have influenza are usually recovered within one week and symptoms are gone within 2 weeks.
However, people with immature and weakened immune systems including young children under age 5, adults older than age 65, elderly in nursing homes and other long-term care facilities, and chronic illnesses, such as asthma, heart disease, kidney disease, liver disease, and diabetes are not only associated with the risk of influenza but also increase the risk of influenza deadly complications.
Pregnant women and women up to two weeks postpartum due to changes in the immune system are more prone to influenza and influenza complications.
The most common H and N subtypes are influenza A which has been mutated to affect the combination of human, swine, and bird flu viruses, including
* H1N1 - Swine Flu
H1N1 normally is only transmitted among pigs. However, as of today, H1N1 has become the first flu pandemic in the world that causes respiratory illness.
* H5N1 - Bird Flu
H5N1 is the strain of influenza known as a bird or avian flu. Before, it is transmitted between birds, but today, it can be passed from bird to human. The strain is dangerous to humans with high death rates.
The most common symptoms of influenza are high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and persistent fatigue.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the prevention and treatment of influenza, researchers compared the effect of two preparations of bromeline ("Sigma Co., Catalogues' Nos. B2252 and B5144).s
According to the tested assay, in the influenza A(H1N1) virus, B5144 did not have any impact on it under similar experimental conditions.
Furthermore, B5144 also showed an incomplete effect on the influenza A(H3N2) virus with particles (with intact external coatings).
However, enzyme B2252 was effective for all viruses selected for testing, with the highest effect noted for influenza A(H1N1) and B viruses.
In other words, not all bromines are the same, some are more effective in the inhibition of viral influenza than others.
Taken together, preparations of bromelain generation from bromelain may be considered a remedy for the prevention and treatment of influenza, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage by Wang W1, Suguitan AL Jr, Zengel J, Chen Z, Jin H. (PubMed)
(2) [The use of bromelain in obtaining the subviral particles of influenza A and B viruses].[Article in Russian] by Ivanova VT, Kordiukova LV, Manykin AA, Burtseva EI, Zagorskaia IuV, Oskerko TA, Slepushkin AN. (PubMed)
Influenza A, B, C, and D are 4 types of flu influenza. Influenza virus A and B are seasonal flu that occur during the fall, winter, and early spring, They cause sniffling, aching, coughing, running and stuffy nose, and fever, affecting over 20% of the general population.
Influenza virus type C in the virus family Orthomyxoviridae tends to cause mild upper respiratory infections, similar to those of cold.
Influenza D viruses only affect cattle.
Individuals who have influenza are usually recovered within one week and symptoms are gone within 2 weeks.
However, people with immature and weakened immune systems including young children under age 5, adults older than age 65, elderly in nursing homes and other long-term care facilities, and chronic illnesses, such as asthma, heart disease, kidney disease, liver disease, and diabetes are not only associated with the risk of influenza but also increase the risk of influenza deadly complications.
Pregnant women and women up to two weeks postpartum due to changes in the immune system are more prone to influenza and influenza complications.
The most common H and N subtypes are influenza A which has been mutated to affect the combination of human, swine, and bird flu viruses, including
* H1N1 - Swine Flu
H1N1 normally is only transmitted among pigs. However, as of today, H1N1 has become the first flu pandemic in the world that causes respiratory illness.
* H5N1 - Bird Flu
H5N1 is the strain of influenza known as a bird or avian flu. Before, it is transmitted between birds, but today, it can be passed from bird to human. The strain is dangerous to humans with high death rates.
The most common symptoms of influenza are high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and persistent fatigue.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the prevention and treatment of influenza, researchers compared the effect of two preparations of bromeline ("Sigma Co., Catalogues' Nos. B2252 and B5144).s
According to the tested assay, in the influenza A(H1N1) virus, B5144 did not have any impact on it under similar experimental conditions.
Furthermore, B5144 also showed an incomplete effect on the influenza A(H3N2) virus with particles (with intact external coatings).
However, enzyme B2252 was effective for all viruses selected for testing, with the highest effect noted for influenza A(H1N1) and B viruses.
In other words, not all bromines are the same, some are more effective in the inhibition of viral influenza than others.
Taken together, preparations of bromelain generation from bromelain may be considered a remedy for the prevention and treatment of influenza, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage by Wang W1, Suguitan AL Jr, Zengel J, Chen Z, Jin H. (PubMed)
(2) [The use of bromelain in obtaining the subviral particles of influenza A and B viruses].[Article in Russian] by Ivanova VT, Kordiukova LV, Manykin AA, Burtseva EI, Zagorskaia IuV, Oskerko TA, Slepushkin AN. (PubMed)
Herbal #Turmeric's #Curcumin Exert Stroke-Preventive Activity, Researchers Say
Kyle J. Norton
A stroke is a medical condition caused by poor blood flow to the brain, leading to the death of the neurons.
Besides cancer and heart diseases, stroke is the third leading cause of death in the US. According to the statistics, approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.
The causes of stroke are either associated with plaque build-up on the arteries, leading to reduce blood flow to the brain, depending on the location of an obstruction or the breaking of small blood vessels in the brain.
In other words, strokes can be classified into 2 types
* Ischemic stroke is caused by a clot or other blockage within an artery that leads to the brain.
* Hemorrhagic stroke caused by the vessel in the brain rupturing that results in blood leaking into the brain.
Stroke is caused by a number of factors. Epidemiological studies suggest high blood pressure, medical conditions such as diabetes, heart disease, smoking, age, gender ethnicity, and personal or family history of stroke are some of the prevalent risk factors.
Some researchers in the examination of the rise of stroke in North America suggested that stroke may be associated with the promotion of the Western diet over the past few decades.
The American Heart Association wrote, "Western" diets consisting of red and processed meats, refined grains, sweets, and desserts may be associated with a greater risk of stroke, according to a study published in this week's rapid access issue of Stroke: Journal of the American Heart Association".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a natural compound for the treatment of stroke prevention scientists evaluated the protective effects of curcumin, the best-known member and is mainly extracted from turmeric preventive effect on stroke.
The study included stroke-prone spontaneously hypertensive rats (SHRsp) randomly divided into either a control group (n = 10, saline or curcumin (100 mg/kg/day)) or curcumin group (n = 10) administrated daily.
According to the tested assays, administration of curcumin significantly delayed the onset of stroke and increased the survival of SHRsp by decreasing the expression of ROS and improving endothelial-dependent relaxation of carotid arteries.
However, according to the RT-PCR and immunoblotting, curcumin showed no statistical significance in the presence of UCP2 inhibitor genipin by blocking the decrease of ROS and increase of NO production.
Where genipin is a chemical compound found in gardenia fruit extract.
In other words, for curcumin to exert its stroke-preventive activity, curcumin cannot be consumed together with gardenia fruit.
Additionally, in the study to examine the curcumin effect during the stroke, researchers found that curcumin encapsulated in exosomes, nano-vesicles (<200 nm), shows therapeutic effects in brain diseases, such as stroke.
Taken together, turmeric processed with a high amount of bioactive compound curcumin may be considered supplements for the prevention of stroke, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function by Lan C1,2, Chen X1,2,3, Zhang Y1,2, Wang W1,2, Wang WE1,2, Liu Y1,2, Cai Y1,2,4, Ren H1,2, Zheng S1,2, Zhou L5,6, Zeng C. (PubMed)
(2) Epigenetic impact of curcumin on stroke prevention by Kalani A1, Kamat PK, Kalani K, Tyagi N. (PubMed)
(3) Western' Diets May Be Linked To Greater Stroke Ris by the American Heart Association. (Science Daily)
A stroke is a medical condition caused by poor blood flow to the brain, leading to the death of the neurons.
Besides cancer and heart diseases, stroke is the third leading cause of death in the US. According to the statistics, approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.
The causes of stroke are either associated with plaque build-up on the arteries, leading to reduce blood flow to the brain, depending on the location of an obstruction or the breaking of small blood vessels in the brain.
In other words, strokes can be classified into 2 types
* Ischemic stroke is caused by a clot or other blockage within an artery that leads to the brain.
* Hemorrhagic stroke caused by the vessel in the brain rupturing that results in blood leaking into the brain.
Stroke is caused by a number of factors. Epidemiological studies suggest high blood pressure, medical conditions such as diabetes, heart disease, smoking, age, gender ethnicity, and personal or family history of stroke are some of the prevalent risk factors.
Some researchers in the examination of the rise of stroke in North America suggested that stroke may be associated with the promotion of the Western diet over the past few decades.
The American Heart Association wrote, "Western" diets consisting of red and processed meats, refined grains, sweets, and desserts may be associated with a greater risk of stroke, according to a study published in this week's rapid access issue of Stroke: Journal of the American Heart Association".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a natural compound for the treatment of stroke prevention scientists evaluated the protective effects of curcumin, the best-known member and is mainly extracted from turmeric preventive effect on stroke.
The study included stroke-prone spontaneously hypertensive rats (SHRsp) randomly divided into either a control group (n = 10, saline or curcumin (100 mg/kg/day)) or curcumin group (n = 10) administrated daily.
According to the tested assays, administration of curcumin significantly delayed the onset of stroke and increased the survival of SHRsp by decreasing the expression of ROS and improving endothelial-dependent relaxation of carotid arteries.
However, according to the RT-PCR and immunoblotting, curcumin showed no statistical significance in the presence of UCP2 inhibitor genipin by blocking the decrease of ROS and increase of NO production.
Where genipin is a chemical compound found in gardenia fruit extract.
In other words, for curcumin to exert its stroke-preventive activity, curcumin cannot be consumed together with gardenia fruit.
Additionally, in the study to examine the curcumin effect during the stroke, researchers found that curcumin encapsulated in exosomes, nano-vesicles (<200 nm), shows therapeutic effects in brain diseases, such as stroke.
Taken together, turmeric processed with a high amount of bioactive compound curcumin may be considered supplements for the prevention of stroke, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
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Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function by Lan C1,2, Chen X1,2,3, Zhang Y1,2, Wang W1,2, Wang WE1,2, Liu Y1,2, Cai Y1,2,4, Ren H1,2, Zheng S1,2, Zhou L5,6, Zeng C. (PubMed)
(2) Epigenetic impact of curcumin on stroke prevention by Kalani A1, Kamat PK, Kalani K, Tyagi N. (PubMed)
(3) Western' Diets May Be Linked To Greater Stroke Ris by the American Heart Association. (Science Daily)
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