Kyle J. Norton
Antioxidants are stable molecules that inhibit oxidation.
Antioxidant enzymes either produced by the host body or from dietary sources play a critical role in the prevention of oxidative stress by balancing the expression of free radicals.
Free radicals are everywhere. Any chemical containing oxygen molecules including environmental and behavioral factors such as exposure to radiation and toxic chemicals and smoking can dramatically increase the number of free radicals in the body.
Free radicals internally are produced during the course of cell metabolism.
Oxidative stress is caused by the overexpression of free radicals compared to the low levels of antioxidant enzymes produced by the host. Over time, oxidative stress can induce proteins, lipids, and cell damage, leading to the facilitation of heart diseases, diabetes, stroke, cancer...
In other words, the chain reaction of free radicals that cannot be stopped is a leading cause of oxidative stress-induced chronic disease.
More precisely, if the antioxidant enzymes no longer can perform the function of balancing the free radicals in the body, oxidative stress occurs.
Some researchers suggested the rise of oxidative stress in the US may be correlated to the promotion of the Western diet over the past few decades.
Dr. Ildiko Erdelyi wrote, "WD induces inflammatory changes, expression profiles of a broad spectrum of inflammatory proteins were performed and numbers of lamina propria macrophages were determined with semiquantitative morphometry".
And, "WD significantly alters the local colonic immune response. Collectively, these data suggest that consumption of a WD interferes with networks of related biological response pathways involving colonic lipid metabolism, oxidative stress, and the immune response".
The results strongly suggested that by maintaining a healthy ratio of antioxidants and free radicals, diseases associated with oxidative stress can be preventable.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a closely related of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
With an aim to find a potential and natural compound for the prevention and treatment of diseases associated with oxidative stress, researchers examined the effect of conventional, organic, and mixed cultivation practices on the content of total phenolics, total flavonoids, and antioxidant activity in two varieties of onion grown over 4 years in a split-plot factorial systems comparison trial.
According to the experiment, levels of total phenolics and total flavonoids were significantly different between organic and conventional production systems.
Levels of antioxidants such as levels of total phenolics, and total flavonoids are significantly higher under fully organic growth compared to conventional growth.
In other words, if you are looking for the best onion with antioxidant activity, organic cultivation onion is a better choice
Based on the findings, researchers said, "organic cultivation practices resulted in significantly higher levels of potentially bioactive compounds in onion".
Taken together, onion may be considered a remedy for the prevention and treatment of diseases associated with oxidation, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antihyperlipidemic and Antioxidative Potentials of Onion (Allium cepa L.) Extract Fermented with a Novel Lactobacillus casei HD-010 by Yang WS1,2, Kim JC3, Lee JY4, Kim CH5, Hwang CW6. (PubMed)
(2) Evaluation of polyphenolic content and antioxidant activity in two onion varieties grown under organic and conventional production systems by Ren F1,2, Reilly K1, Gaffney M1, Kerry JP2, Hossain M1, Rai DK. (PubMed)
(3) Western-Style Diets Induce Oxidative Stress and Dysregulate Immune Responses in the Colon in a Mouse Model of Sporadic Colon Cancer by Ildiko Erdelyi,4 Natasha Levenkova,5 Elaine Y. Lin,8 John T. Pinto,9 Martin Lipkin,4Fred W. Quimby,6 and Peter R. Holt. (PMC)
Thursday, 26 October 2023
#Leeks Inhibit Parameters Associated with the Onset of #HighBloodCholesterol, Scientists Say
Kyle J. Norton
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques to build up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
Low-density lipoprotein is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However, overexpression of LDL can induce plaque accumulated on the arterial wall, leading to atherosclerosis, a major cause of cardiovascular disease.
Low-density lipoprotein is produced by the liver or from dietary sources. High-density lipoprotein neutralizes the levels of LDL by returning them to the liver.
Some researchers suggested that a diet high in trans fats, saturated fat, sugar, smoking, and medical conditions such as diabetes or high blood pressure are associated with an increased risk of high blood cholesterol.
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, being physically inactive, smoking, and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet rich in saturated and trans fat, and processed foods is the major cause of high blood cholesterol in the Western world.
Epidemiological studies indicated a healthy diet that contains a high amount of fruits and vegetables and whole grains has a positive on blood cholesterol. In other words, hyperlipidemia can be prevented by a healthy diet.
Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed usually reach maturity in the autumn months, and have few pest or disease problems.
In finding a potential plant that processes anti-high blood cholesterol, researchers examined the effects of oral administration of Persian leek on plasma and liver lipids.
The study included male Syrian hamsters that were randomly divided into three groups: control (standard diet), high-fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks.
Before treatment, a high-fat diet showed an increase in plasma and liver lipids compared to a standard diet.
Administration of Persian leek to the high-fat/high-cholesterol diet resulted in no significant changes in the concentration of the plasma lipids or liver cholesterol.
Liver triglycerides (TG), plasma Alanine aminotransferase, and gene expression of tumor necrosis factor- α associated with liver stress marker and pro-inflammatory cytokines, compared to high-fat diet only.
Collectively, researchers said, "Persian leek might be considered as a herbal food that can reduce liver TG accumulation induced by high-fat diets".
Taken together, leeks may be considered a functional food for the prevention and treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ high-cholesterol diet by Fatoorechi V1, Rismanchi M2, Nasrollahzadeh J. (PubMed)
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques to build up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
Low-density lipoprotein is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However, overexpression of LDL can induce plaque accumulated on the arterial wall, leading to atherosclerosis, a major cause of cardiovascular disease.
Low-density lipoprotein is produced by the liver or from dietary sources. High-density lipoprotein neutralizes the levels of LDL by returning them to the liver.
Some researchers suggested that a diet high in trans fats, saturated fat, sugar, smoking, and medical conditions such as diabetes or high blood pressure are associated with an increased risk of high blood cholesterol.
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, being physically inactive, smoking, and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet rich in saturated and trans fat, and processed foods is the major cause of high blood cholesterol in the Western world.
Epidemiological studies indicated a healthy diet that contains a high amount of fruits and vegetables and whole grains has a positive on blood cholesterol. In other words, hyperlipidemia can be prevented by a healthy diet.
Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed usually reach maturity in the autumn months, and have few pest or disease problems.
In finding a potential plant that processes anti-high blood cholesterol, researchers examined the effects of oral administration of Persian leek on plasma and liver lipids.
The study included male Syrian hamsters that were randomly divided into three groups: control (standard diet), high-fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks.
Before treatment, a high-fat diet showed an increase in plasma and liver lipids compared to a standard diet.
Administration of Persian leek to the high-fat/high-cholesterol diet resulted in no significant changes in the concentration of the plasma lipids or liver cholesterol.
Liver triglycerides (TG), plasma Alanine aminotransferase, and gene expression of tumor necrosis factor- α associated with liver stress marker and pro-inflammatory cytokines, compared to high-fat diet only.
Collectively, researchers said, "Persian leek might be considered as a herbal food that can reduce liver TG accumulation induced by high-fat diets".
Taken together, leeks may be considered a functional food for the prevention and treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ high-cholesterol diet by Fatoorechi V1, Rismanchi M2, Nasrollahzadeh J. (PubMed)
#StrawberryExtract Inhibits #BreastCancer Cells by Blocking Proliferation and Inducing Apoptosis, Scientists Say
Kyle J. Norton
Breast cancer (malignant breast neoplasm) is a type of irregular cell growth that starts either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk in the breast.
In rare cases, breast cancer starts in other areas of the breast.
In 2010, over 250,000 new breast cancer cases were diagnosed in women in the U.S. alone. The risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
The causes of breast cancer are unknown. Researchers do not know, people with the same health conditions and similar family history, some are more susceptible to the onset of the disease, while others do not.
However, an increase in aging, a history of breast conditions, such as previous breast cancer, breast density, use of hormone estrogen therapy, overweight and obese, and excessive alcohol consumption are some major risk factors that can elevate the development of breast cancer.
Furthermore, genetic mutation of certain inherited from the parent such as genes BRCA1 and BRCA2 are also the prevalent risk factors of breast cancer. There is an estimation that 33% of women who carry a harmful mutation in PALB2 will develop breast cancer by age 70 years.
According to the article by the National Institute of Health, " Several different tests are available. Some tests look for a specific harmful BRCA1 orBRCA2 gene mutation that has already been identified in another family member. Other tests check for all of the known harmful mutations in both genes. Multigene (panel) testing uses next-generation sequencing to look for harmful mutations in many genes that are associated with an increased risk of breast and ovarian cancer, including BRCA1 and BRCA2, at the same time".
If you have a family history of genetic mutation involved in breast cancer, please make sure that you have them checked to rule out the possibility.
Strawberry is a genius of Fragaria × ananassa and belongs to the family Roseaceae.
The fruit has been grown all over the world with a suitable climate for commercial profits and health benefits.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
Epidemiological studies strongly agree that the consumption of berry fruits, including strawberries has beneficial effects on human health and reduces the risk of chronic diseases, including breast cancer.
The Indian Institute of Science conducted an experiment to examine whether a methanolic extract of strawberry (MESB) fruits processes anticancer activity in leukemia (CEM) and breast cancer (T47D) cell lines ex vivo and its cancer therapeutic and chemopreventive potential in mice models,
* Mice-bearing breast adenocarcinoma with MESB treated by the extract blocked the proliferation of tumor cells in a time-dependent manner.
* Application of the extract also increases lifespan in the cancer-bearing animal model.
* MESB treatment affected tumor cell proliferation by activating apoptosis and did not result in any side effects
* Finally, MESB treatment also induces the intrinsic pathway of apoptosis by activating p73 in breast cancer cells, caused by the mutation of tumor suppressor gene p53.
These results revealed that strawberry fruits possess both cancer-preventive and therapeutic values.
Additionally, in the study to test for anti-breast cancer activity in extracts of six popularly consumed berries--blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry conducted by the University of California, researchers found that strawberry and other berry extracts exert their ability to inhibit the growth of human breast cancer cell line MCF-7 at concentrations ranging from 25 to 200 micro g/mL.
Moreover, researchers also discovered the apoptosis rate of breast cancer cell killing is increased with increasing concentration of the extract. These findings suggested that strawberry extract may have the potential to kill 100% of the breast cancer cells in a dose-dependent manner.
In comparison to other extracts, black raspberry and strawberry extracts showed the most significant pro-apoptotic effects against breast cell lines.
However, due to the limitation of the above studies, further data collection on large example size and multi-center studies performed with human consumption of whole food during the course of the disease will be necessary to complete the picture of strawberry anti-breast cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibit tumor progression in mice, by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC. (PubMed)
(2) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.by Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)
Breast cancer (malignant breast neoplasm) is a type of irregular cell growth that starts either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk in the breast.
In rare cases, breast cancer starts in other areas of the breast.
In 2010, over 250,000 new breast cancer cases were diagnosed in women in the U.S. alone. The risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
The causes of breast cancer are unknown. Researchers do not know, people with the same health conditions and similar family history, some are more susceptible to the onset of the disease, while others do not.
However, an increase in aging, a history of breast conditions, such as previous breast cancer, breast density, use of hormone estrogen therapy, overweight and obese, and excessive alcohol consumption are some major risk factors that can elevate the development of breast cancer.
Furthermore, genetic mutation of certain inherited from the parent such as genes BRCA1 and BRCA2 are also the prevalent risk factors of breast cancer. There is an estimation that 33% of women who carry a harmful mutation in PALB2 will develop breast cancer by age 70 years.
According to the article by the National Institute of Health, " Several different tests are available. Some tests look for a specific harmful BRCA1 orBRCA2 gene mutation that has already been identified in another family member. Other tests check for all of the known harmful mutations in both genes. Multigene (panel) testing uses next-generation sequencing to look for harmful mutations in many genes that are associated with an increased risk of breast and ovarian cancer, including BRCA1 and BRCA2, at the same time".
If you have a family history of genetic mutation involved in breast cancer, please make sure that you have them checked to rule out the possibility.
Strawberry is a genius of Fragaria × ananassa and belongs to the family Roseaceae.
The fruit has been grown all over the world with a suitable climate for commercial profits and health benefits.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
Epidemiological studies strongly agree that the consumption of berry fruits, including strawberries has beneficial effects on human health and reduces the risk of chronic diseases, including breast cancer.
The Indian Institute of Science conducted an experiment to examine whether a methanolic extract of strawberry (MESB) fruits processes anticancer activity in leukemia (CEM) and breast cancer (T47D) cell lines ex vivo and its cancer therapeutic and chemopreventive potential in mice models,
* Mice-bearing breast adenocarcinoma with MESB treated by the extract blocked the proliferation of tumor cells in a time-dependent manner.
* Application of the extract also increases lifespan in the cancer-bearing animal model.
* MESB treatment affected tumor cell proliferation by activating apoptosis and did not result in any side effects
* Finally, MESB treatment also induces the intrinsic pathway of apoptosis by activating p73 in breast cancer cells, caused by the mutation of tumor suppressor gene p53.
These results revealed that strawberry fruits possess both cancer-preventive and therapeutic values.
Additionally, in the study to test for anti-breast cancer activity in extracts of six popularly consumed berries--blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry conducted by the University of California, researchers found that strawberry and other berry extracts exert their ability to inhibit the growth of human breast cancer cell line MCF-7 at concentrations ranging from 25 to 200 micro g/mL.
Moreover, researchers also discovered the apoptosis rate of breast cancer cell killing is increased with increasing concentration of the extract. These findings suggested that strawberry extract may have the potential to kill 100% of the breast cancer cells in a dose-dependent manner.
In comparison to other extracts, black raspberry and strawberry extracts showed the most significant pro-apoptotic effects against breast cell lines.
However, due to the limitation of the above studies, further data collection on large example size and multi-center studies performed with human consumption of whole food during the course of the disease will be necessary to complete the picture of strawberry anti-breast cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibit tumor progression in mice, by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC. (PubMed)
(2) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.by Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)
Tuesday, 24 October 2023
#Herbal #BearberryLeaf and Its Extract Exert Anti-High Blood Pressure Activity, Scientists Find
Kyle J. Norton
Herbal Barberry may be considered as a functional food and natural alternative in the prevention and treatment of high blood pressure quickly with no adverse effects, some scientists suggested. High blood pressure or hypertension is a medical condition characterized by abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
The normal range of blood pressure is 120 over 80. The number in the top is systolic blood pressure, and the bottom is called the diastolic blood pressure.
Researchers do not know the exact causes of hypertension. However, researchers do know that certain preventable risk factors such as smoking, being overweight or obese, physical inactivity,.... and excessive alcohol drinking are associated with an increased risk of hypertension.
Prolong periods of raising the pressure of the heart can lead to damage to the body in many ways.
Uncontrolled high blood pressure can lead to stroke and heart disease by damaging and weakening your brain's blood vessels, a blood clot in the arteries.
An unhealthy diet high in salt, sugar, process products, genetic mutation, aging, family history,... and long-term stress also have a substantial impact on the onset of hypertension.
Dr. Kim EJ, the lead author in the study of the dietary effect in patients with borderline hypertension, suggested, " a short-term (12 weeks) lifestyle intervention had positive effects on blood pressure control and weight reduction in the subjects, but not on their blood levels of adipokines. It is interesting that the blood level of baseline leptin was negatively associated with the changes in blood pressure after this short-term intervention"(3).
The results showed that long-term dietary intervention should have a strong impact on keeping blood pressure in check.
Adipocytes found in the obese population may contribute to the high prevalence of hypertension.
Leptin, a chemical compound in the blood plays a critical role in the regulation and arterial hypertension
Conventional blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they can induce serious side effects, including common gastrointestinal discomfort and psychological symptoms,
Lifelong intake of hypertension medicine can cause erectile dysfunction.
If you take the medicine in the long term, please make sure you discuss the side effects with your doctor.
Bearberries are 3 species in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herbs have been used in traditional medicine as diuretic agents and to treat urinary problems, including bladder infections, kidney infections, kidney stones,.... and pelvic pain.
The Chemicals Ingredients
It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides,..... and flavonoids.
With the aim to find the possible hypotensive activity of aqueous extract of Vaccinium Arctostaphylos leaves, the Shiraz University of Medical Sciences conducted an experiment on rats with two-kidney, one-clip hypertension.
All rats were subjected to a sham operation of the placement of a Plexiglass clip on left renal arteries.
After four weeks of surgery, renal artery-clipped rats were either injected intravenously with different doses of the extract at 10, 25, or 75 mg/kg or normal saline.
The mean blood pressure and heart rate were measured before and 20, 40, and 60 minutes after vehicle or drug administration, researchers found that
* The group given normal saline has a significantly higher mean blood pressure, heart, and right kidney weights, lower left kidney weight, and significantly indifferent heart rate.
* The treatment group with the injection of the extract at 75 mg/kg exerts a reduction of the mean blood pressure at 20, 40, and 60 minutes after administration without changing the heart rate.
* However, groups treated with doses of but 10 or 25 mg/kg show an insignificant change in mean blood pressure compared to groups administrated with the extract at 75 mg/kg.
These results suggested that bearberry leaf extract has the potential to reduce blood pressure in a dose-dependent manner.
Dr. Khalili A, the lead author of the final report, wrote, "... at a higher dose the extract did have hypotensive activity without changing the heart rate".
Truly, the Laboratoire de Pharmacognosie study of Arctostaphylos uva-ursi and hydroalcoholic extracts suggested that the test substances may process a pharmacological effect in reduced blood pressure through increasing urine flow and urinary sodium excretion in vitro.
Taking together, herbal bearberry and its extract may be considered a functional food for the treatment of high blood pressure.
However, further data collection on large example size and multi-center studies performed with human consumption of the herbal leaf extract during the course of the disease will be necessary to complete the picture of bearberry hypotensive possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the karate GB Daily, etc.,
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. The effects of aqueous extract of vaccinium arctostaphylos leaves on blood pressure in renal hypertensive rats. by Khalili A, Khosravi MB, Nekooeian AA. (PubMed)
2. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats by Beaux D, Fleurentin J, Mortier F.(PubMed)
(3) Effects of a 12-week lifestyle intervention on health outcome and serum adipokines in middle-aged Korean men with borderline high blood pressure by Kim EJ1, Cho SW, Kang JY, Choi TI, Park YK(PubMed)
Herbal Barberry may be considered as a functional food and natural alternative in the prevention and treatment of high blood pressure quickly with no adverse effects, some scientists suggested. High blood pressure or hypertension is a medical condition characterized by abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
The normal range of blood pressure is 120 over 80. The number in the top is systolic blood pressure, and the bottom is called the diastolic blood pressure.
Researchers do not know the exact causes of hypertension. However, researchers do know that certain preventable risk factors such as smoking, being overweight or obese, physical inactivity,.... and excessive alcohol drinking are associated with an increased risk of hypertension.
Prolong periods of raising the pressure of the heart can lead to damage to the body in many ways.
Uncontrolled high blood pressure can lead to stroke and heart disease by damaging and weakening your brain's blood vessels, a blood clot in the arteries.
An unhealthy diet high in salt, sugar, process products, genetic mutation, aging, family history,... and long-term stress also have a substantial impact on the onset of hypertension.
Dr. Kim EJ, the lead author in the study of the dietary effect in patients with borderline hypertension, suggested, " a short-term (12 weeks) lifestyle intervention had positive effects on blood pressure control and weight reduction in the subjects, but not on their blood levels of adipokines. It is interesting that the blood level of baseline leptin was negatively associated with the changes in blood pressure after this short-term intervention"(3).
The results showed that long-term dietary intervention should have a strong impact on keeping blood pressure in check.
Adipocytes found in the obese population may contribute to the high prevalence of hypertension.
Leptin, a chemical compound in the blood plays a critical role in the regulation and arterial hypertension
Conventional blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they can induce serious side effects, including common gastrointestinal discomfort and psychological symptoms,
Lifelong intake of hypertension medicine can cause erectile dysfunction.
If you take the medicine in the long term, please make sure you discuss the side effects with your doctor.
Bearberries are 3 species in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herbs have been used in traditional medicine as diuretic agents and to treat urinary problems, including bladder infections, kidney infections, kidney stones,.... and pelvic pain.
The Chemicals Ingredients
It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides,..... and flavonoids.
With the aim to find the possible hypotensive activity of aqueous extract of Vaccinium Arctostaphylos leaves, the Shiraz University of Medical Sciences conducted an experiment on rats with two-kidney, one-clip hypertension.
All rats were subjected to a sham operation of the placement of a Plexiglass clip on left renal arteries.
After four weeks of surgery, renal artery-clipped rats were either injected intravenously with different doses of the extract at 10, 25, or 75 mg/kg or normal saline.
The mean blood pressure and heart rate were measured before and 20, 40, and 60 minutes after vehicle or drug administration, researchers found that
* The group given normal saline has a significantly higher mean blood pressure, heart, and right kidney weights, lower left kidney weight, and significantly indifferent heart rate.
* The treatment group with the injection of the extract at 75 mg/kg exerts a reduction of the mean blood pressure at 20, 40, and 60 minutes after administration without changing the heart rate.
* However, groups treated with doses of but 10 or 25 mg/kg show an insignificant change in mean blood pressure compared to groups administrated with the extract at 75 mg/kg.
These results suggested that bearberry leaf extract has the potential to reduce blood pressure in a dose-dependent manner.
Dr. Khalili A, the lead author of the final report, wrote, "... at a higher dose the extract did have hypotensive activity without changing the heart rate".
Truly, the Laboratoire de Pharmacognosie study of Arctostaphylos uva-ursi and hydroalcoholic extracts suggested that the test substances may process a pharmacological effect in reduced blood pressure through increasing urine flow and urinary sodium excretion in vitro.
Taking together, herbal bearberry and its extract may be considered a functional food for the treatment of high blood pressure.
However, further data collection on large example size and multi-center studies performed with human consumption of the herbal leaf extract during the course of the disease will be necessary to complete the picture of bearberry hypotensive possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the karate GB Daily, etc.,
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. The effects of aqueous extract of vaccinium arctostaphylos leaves on blood pressure in renal hypertensive rats. by Khalili A, Khosravi MB, Nekooeian AA. (PubMed)
2. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats by Beaux D, Fleurentin J, Mortier F.(PubMed)
(3) Effects of a 12-week lifestyle intervention on health outcome and serum adipokines in middle-aged Korean men with borderline high blood pressure by Kim EJ1, Cho SW, Kang JY, Choi TI, Park YK(PubMed)
#Herbal #Turmeric's #Curcumin Processes Anti Bacterial Activity, Researchers Say
Kyle J. Norton
Gastritis is a group of conditions associated with the inflammation of the lining of the stomach caused by infection of the bacterium, leading to stomach ulcers developing.
A stomach ulcer is an open sore in the lining of the stomach. In most cases, it is a result of bacterial infection that leads to the erosion of the gastric lining by stomach acid.
Other causes of gastritis are long-term excessive alcohol consumption and the use of certain medication such as aspirin.
There are 2 types of gastritis
* Acute gastritis occurs suddenly as a result of inflammation or swelling in the lining of the stomach. and only affects the stomach and induces nausea or vomiting,
* Chronic gastritis is a condition that develops slowly due to chronic inflammation or damage of the stomach lining that has not healed.
Patients with chronic gastritis if untreated were found to have a substantial risk of stomach cancer.
The most common symptoms of gastritis are a burning sensation or pain in the upper abdomen, nausea, vomiting, and abnormal feeling of fullness in the upper abdomen after eating.
Out of many risk factors involved in the onset of the condition, some researchers in the observation of the correlation of high-fat diet-induced obesity over the past few decades, in the risk of gastritis wrote, "Obesity has become a major concern among gastroenterologists due to its large influence on gastrointestinal and hepatic diseases: reflux esophagitis, pancreatitis, gallstone disease, liver fibrosis, and neoplastic tumors of the esophagus, pancreas, and colon".
And, "the effects of obesity on endoscopic gastritis in subjects undergoing health check-up examination, and demonstrated that adiponectin, a bioactive molecule released from visceral fat, could be a protective factor of endoscopic gastritis".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a potential ingredient for the treatment of gastric inflammation, researchers examined the effect of diterpenoid C extracted from radix curcuma on Helicobacter pylori (H. pylori)-infected inflammation, and intestinal metaplasia.
The study included human gastric epithelial gastric epithelium cell line (GES-1) infected by I-type H. pylori treated with radix Curcuma (RC)-derived diterpenoid C of different concentrations (5, 10, 20 μg/mL) and amoxicillin.
According to the MTT assay, IC5 of RC-derived diterpenoid C and amoxicillin of 5 μg/mL inhibited the progression rate of GES-1.
The combination also inhibited the production of pro-inflammatory cytokines and exhibited the production of anti-inflammatory cytokines associated with the injection of I-type H. pylori in the GES-1,
particularly, at 12, 24, 48, and 72 h points.
In other words, the combination protects the stomach against gastric inflammation by blocking the activation of a protein involved in the stimulation of pro-inflammatory cytokines.
Based on the findings, researchers wrote, "RC-derived diterpenoid C can block NF-κB signal pathway, effectively reducing the secretion of H. pylori-induced proinflammatory cytokine and increasing the secretion of anti-inflammatory cytokine".
In Helicobacter pylori infection of the lining of the stomach induces an array of inflammatory cytokine production that leads to gastritis and peptic ulcer disease, researchers at the Uttaradit Hospital conducted an experiment to investigate the effect of curcumin on the production of interleukin (IL)-8, IL-1beta, tumor necrosis factor (TNF)-alpha and cyclooxygenase (COX)-2 in gastric mucosa from H. pylori-infected gastritis patients.
Selected patients were randomly assigned to receive either OAM (Omeprazole, Amoxicillin, and Metronidazole) treatment and/or a course of curcumin.
According to the tested assays, curcumin alone may have a limited anti-bactericidal effect on H. pylori, and on the production of inflammatory cytokines compared to those of the OAM group.
However, the curcumin group showed significant relieving symptoms with a lower rate in the eradication rate of H. pylori and no decreased cytokine production.
Precisely, curcumin used alone has limited efficacy compared to that of the combination in reducing gastric inflammation.
Taken together, turmeric processed abundant bioactive ingredient curcumin may be combined with other conventional medicines for the prevention and treatment of gastric inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of radix curcuma-derived diterpenoid C on Helicobacter pylori-induced inflammation and nuclear factor kappa B signal pathways by Huang X1, Lv B, Zhang S, Dai Q, Chen BB, Meng LN. (PubMed)
(2) Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients by Koosirirat C1, Linpisarn S, Changsom D, Chawansuntati K, Wipasa J. (PubMed)
(3) Is obesity a new risk factor for gastritis? by Yamamoto S1, Watabe K, Takehara T. (PubMed)
Gastritis is a group of conditions associated with the inflammation of the lining of the stomach caused by infection of the bacterium, leading to stomach ulcers developing.
A stomach ulcer is an open sore in the lining of the stomach. In most cases, it is a result of bacterial infection that leads to the erosion of the gastric lining by stomach acid.
Other causes of gastritis are long-term excessive alcohol consumption and the use of certain medication such as aspirin.
There are 2 types of gastritis
* Acute gastritis occurs suddenly as a result of inflammation or swelling in the lining of the stomach. and only affects the stomach and induces nausea or vomiting,
* Chronic gastritis is a condition that develops slowly due to chronic inflammation or damage of the stomach lining that has not healed.
Patients with chronic gastritis if untreated were found to have a substantial risk of stomach cancer.
The most common symptoms of gastritis are a burning sensation or pain in the upper abdomen, nausea, vomiting, and abnormal feeling of fullness in the upper abdomen after eating.
Out of many risk factors involved in the onset of the condition, some researchers in the observation of the correlation of high-fat diet-induced obesity over the past few decades, in the risk of gastritis wrote, "Obesity has become a major concern among gastroenterologists due to its large influence on gastrointestinal and hepatic diseases: reflux esophagitis, pancreatitis, gallstone disease, liver fibrosis, and neoplastic tumors of the esophagus, pancreas, and colon".
And, "the effects of obesity on endoscopic gastritis in subjects undergoing health check-up examination, and demonstrated that adiponectin, a bioactive molecule released from visceral fat, could be a protective factor of endoscopic gastritis".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a potential ingredient for the treatment of gastric inflammation, researchers examined the effect of diterpenoid C extracted from radix curcuma on Helicobacter pylori (H. pylori)-infected inflammation, and intestinal metaplasia.
The study included human gastric epithelial gastric epithelium cell line (GES-1) infected by I-type H. pylori treated with radix Curcuma (RC)-derived diterpenoid C of different concentrations (5, 10, 20 μg/mL) and amoxicillin.
According to the MTT assay, IC5 of RC-derived diterpenoid C and amoxicillin of 5 μg/mL inhibited the progression rate of GES-1.
The combination also inhibited the production of pro-inflammatory cytokines and exhibited the production of anti-inflammatory cytokines associated with the injection of I-type H. pylori in the GES-1,
particularly, at 12, 24, 48, and 72 h points.
In other words, the combination protects the stomach against gastric inflammation by blocking the activation of a protein involved in the stimulation of pro-inflammatory cytokines.
Based on the findings, researchers wrote, "RC-derived diterpenoid C can block NF-κB signal pathway, effectively reducing the secretion of H. pylori-induced proinflammatory cytokine and increasing the secretion of anti-inflammatory cytokine".
In Helicobacter pylori infection of the lining of the stomach induces an array of inflammatory cytokine production that leads to gastritis and peptic ulcer disease, researchers at the Uttaradit Hospital conducted an experiment to investigate the effect of curcumin on the production of interleukin (IL)-8, IL-1beta, tumor necrosis factor (TNF)-alpha and cyclooxygenase (COX)-2 in gastric mucosa from H. pylori-infected gastritis patients.
Selected patients were randomly assigned to receive either OAM (Omeprazole, Amoxicillin, and Metronidazole) treatment and/or a course of curcumin.
According to the tested assays, curcumin alone may have a limited anti-bactericidal effect on H. pylori, and on the production of inflammatory cytokines compared to those of the OAM group.
However, the curcumin group showed significant relieving symptoms with a lower rate in the eradication rate of H. pylori and no decreased cytokine production.
Precisely, curcumin used alone has limited efficacy compared to that of the combination in reducing gastric inflammation.
Taken together, turmeric processed abundant bioactive ingredient curcumin may be combined with other conventional medicines for the prevention and treatment of gastric inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of radix curcuma-derived diterpenoid C on Helicobacter pylori-induced inflammation and nuclear factor kappa B signal pathways by Huang X1, Lv B, Zhang S, Dai Q, Chen BB, Meng LN. (PubMed)
(2) Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients by Koosirirat C1, Linpisarn S, Changsom D, Chawansuntati K, Wipasa J. (PubMed)
(3) Is obesity a new risk factor for gastritis? by Yamamoto S1, Watabe K, Takehara T. (PubMed)
#Herbal #Ashwagandha Inhibits Parameters Associated with the Induction of Middle Cerebral Artery Occlusion (MCAO), Scientists Suggest
Kyle J. Norton
Stroke is a condition in which the brain function is interrupted rapidly due to the loss of blood supply as a result of the blockage of blood such as thrombosis and arterial embolism, or leakage of blood causes of the death of brain cells, according to the article of Mitochondria, oxidative metabolism and cell death in stroke by Sims NR, Muyderman H (September 2009).
In other words, stroke can be caused by either ischemia, due to lack of blood flow or hemorrhagic, due to bleeding.
A stroke is a medical emergency. Early intervention is most cases can minimize brain damage and potential complications.
There is a general belief that stroke is an accumulation over a long period of the unhealthy diet with red meat and processed meats in the induction of artery-clogging.
Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow, and decreased the chance of blood clots.
Sadly, stroke is one of the most common causes of death worldwide.
In the US, according to statistics, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.
Stroke is also the third leading cause of death. Approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of disease associated with plaque accumulated on the arterial wall, researchers examined the effects of Withania somnifera (WS), supplementation on middle cerebral artery occlusion (MCAO) induced mitochondrial dysfunctions in an experimental model of ischemic stroke.
According to the tested analysis, before treatment with WS, tested mice showed an ischemia-reperfusion injury, leading to the increase of the oxidative stress indicated by increased reactive oxygen species and protein carbonyl levels and low levels of antioxidant enzymes.
The untreated mice also exerted decreased antioxidant enzymes superoxide dismutase and catalase activity, along with a reduction in GSH levels and the redox ratio, impaired mitochondrial functions, and enhanced expression of apoptosis markers.
Ischemia-reperfusion injury in the tested mice also induced mitochondrial dysfunctions.
Moreover, the levels of pro-inflammatory and apoptotic proteins were also increased in the untreated mice. The Y maze test also indicated a significant impairment in cognitive functions in the tested animal.
However, WS pre-supplementation ameliorated all parameters associated with the induction of MCAO such as oxidative stress, mitochondrial dysfunctions, apoptosis, and cognitive impairments.
Based on the evidence, researchers said, "WS pre-supplementation in ischemic stroke and are suggestive of its potential application in stroke management".
Taken together, Ashwagandha may be considered a supplement for stroke management, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indian Ginseng (Withania somnifera) supplementation ameliorates oxidative stress and mitochondrial dysfunctions in experimental model of stroke by Sood A1, Mehrotra A1,2, Dhawan DK3, Sandhir R. (PubMed)
Stroke is a condition in which the brain function is interrupted rapidly due to the loss of blood supply as a result of the blockage of blood such as thrombosis and arterial embolism, or leakage of blood causes of the death of brain cells, according to the article of Mitochondria, oxidative metabolism and cell death in stroke by Sims NR, Muyderman H (September 2009).
In other words, stroke can be caused by either ischemia, due to lack of blood flow or hemorrhagic, due to bleeding.
A stroke is a medical emergency. Early intervention is most cases can minimize brain damage and potential complications.
There is a general belief that stroke is an accumulation over a long period of the unhealthy diet with red meat and processed meats in the induction of artery-clogging.
Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow, and decreased the chance of blood clots.
Sadly, stroke is one of the most common causes of death worldwide.
In the US, according to statistics, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.
Stroke is also the third leading cause of death. Approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of disease associated with plaque accumulated on the arterial wall, researchers examined the effects of Withania somnifera (WS), supplementation on middle cerebral artery occlusion (MCAO) induced mitochondrial dysfunctions in an experimental model of ischemic stroke.
According to the tested analysis, before treatment with WS, tested mice showed an ischemia-reperfusion injury, leading to the increase of the oxidative stress indicated by increased reactive oxygen species and protein carbonyl levels and low levels of antioxidant enzymes.
The untreated mice also exerted decreased antioxidant enzymes superoxide dismutase and catalase activity, along with a reduction in GSH levels and the redox ratio, impaired mitochondrial functions, and enhanced expression of apoptosis markers.
Ischemia-reperfusion injury in the tested mice also induced mitochondrial dysfunctions.
Moreover, the levels of pro-inflammatory and apoptotic proteins were also increased in the untreated mice. The Y maze test also indicated a significant impairment in cognitive functions in the tested animal.
However, WS pre-supplementation ameliorated all parameters associated with the induction of MCAO such as oxidative stress, mitochondrial dysfunctions, apoptosis, and cognitive impairments.
Based on the evidence, researchers said, "WS pre-supplementation in ischemic stroke and are suggestive of its potential application in stroke management".
Taken together, Ashwagandha may be considered a supplement for stroke management, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indian Ginseng (Withania somnifera) supplementation ameliorates oxidative stress and mitochondrial dysfunctions in experimental model of stroke by Sood A1, Mehrotra A1,2, Dhawan DK3, Sandhir R. (PubMed)
#BronzeTomato in the Promotion of the Ratio of Gut Microbiota, According to Studies
Kyle J. Norton
Gut Microbiota is a community of microorganisms living in the gastrointestinal tract.
Under normal conditions, gut microbiota plays a critical role in overall health, including the impacts of
* In nutrient metabolism, gut microbiota improves the absorption of dietary nutrients in the digestive system
* In xenobiotic and drug metabolism, gut microbiota protects the body against xenobiotics and drug toxicity by facilitating the excretion.
* Maintenance of the structural integrity of the gut mucosal barrier, gut microbiota enhances the epithelial cells with a function to protect the intestine against invasive pathogens and ensure the function of the intestine in nutrient adsorption.
* In immunomodulation, gut microbiota interact with the immune system against inflammatory immune disorders and inhibit the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
However, an imbalance in the ratio of gut microbiota may have a negative on human health and diseases.
Dr. Yu-Jie Zhang wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells. Gut bacteria play an important role in human health, such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function".
, "However, they can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods for enhancing the ratio of dut microbiota composition researchers examined the effect of consuming tomato products and lycopene on chronic inflammatory disorders associated with intestinal bacteria in an animal model.
The study included Winnie mice as a model of spontaneous ulcerative colitis treated with or without chow enriched with 1% Bronze tomato.
At week 2, the Bronze-enriched chow-treated group showed no macroscopic effect on the IBD symptoms.
However, levels of pro-inflammatory cytokines found in the treated mice were significantly reduced, as observed by the levels of IL17A and IFNγ.
According to the analysis of the microbial composition, two weeks of Bronze enriched diet demonstrated a strong effect in the improvement of the gut microbiota ratio in the tested mice.
In additional differentiation of the results, researchers found that the efficacy of Bronze tomato in the promotion of gut health was attributed to the phytochemical polyphenols presented in the tomato.
Taken together, tomatoes processed with a high amount of lycopene may be considered a dietary supplement for gut health, pending to large sample size and multicenter human study.
Intake of polyphenols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The impact of tomato fruits containing multi-walled carbon nanotube residues on human intestinal epithelial cell barrier function and intestinal microbiome composition by Lahiani MH 1, Khare S, Cerniglia CE, Boy R, Ivanov IN, Khodakovskaya M. (PubMed)
(2) A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions.
Liso M1, De Santis S2, Scarano A3, Verna G4, Dicarlo M5, Galleggiante V6, Campiglia P7, Mastronardi M8, Lippolis A9, Vacca M10, Sobolewski A11, Serino G12, Butelli E13, De Angelis M14, Martin C15, Santino A16, Chieppa M. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li. (PMC)
Gut Microbiota is a community of microorganisms living in the gastrointestinal tract.
Under normal conditions, gut microbiota plays a critical role in overall health, including the impacts of
* In nutrient metabolism, gut microbiota improves the absorption of dietary nutrients in the digestive system
* In xenobiotic and drug metabolism, gut microbiota protects the body against xenobiotics and drug toxicity by facilitating the excretion.
* Maintenance of the structural integrity of the gut mucosal barrier, gut microbiota enhances the epithelial cells with a function to protect the intestine against invasive pathogens and ensure the function of the intestine in nutrient adsorption.
* In immunomodulation, gut microbiota interact with the immune system against inflammatory immune disorders and inhibit the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
However, an imbalance in the ratio of gut microbiota may have a negative on human health and diseases.
Dr. Yu-Jie Zhang wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells. Gut bacteria play an important role in human health, such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function".
, "However, they can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods for enhancing the ratio of dut microbiota composition researchers examined the effect of consuming tomato products and lycopene on chronic inflammatory disorders associated with intestinal bacteria in an animal model.
The study included Winnie mice as a model of spontaneous ulcerative colitis treated with or without chow enriched with 1% Bronze tomato.
At week 2, the Bronze-enriched chow-treated group showed no macroscopic effect on the IBD symptoms.
However, levels of pro-inflammatory cytokines found in the treated mice were significantly reduced, as observed by the levels of IL17A and IFNγ.
According to the analysis of the microbial composition, two weeks of Bronze enriched diet demonstrated a strong effect in the improvement of the gut microbiota ratio in the tested mice.
In additional differentiation of the results, researchers found that the efficacy of Bronze tomato in the promotion of gut health was attributed to the phytochemical polyphenols presented in the tomato.
Taken together, tomatoes processed with a high amount of lycopene may be considered a dietary supplement for gut health, pending to large sample size and multicenter human study.
Intake of polyphenols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The impact of tomato fruits containing multi-walled carbon nanotube residues on human intestinal epithelial cell barrier function and intestinal microbiome composition by Lahiani MH 1, Khare S, Cerniglia CE, Boy R, Ivanov IN, Khodakovskaya M. (PubMed)
(2) A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions.
Liso M1, De Santis S2, Scarano A3, Verna G4, Dicarlo M5, Galleggiante V6, Campiglia P7, Mastronardi M8, Lippolis A9, Vacca M10, Sobolewski A11, Serino G12, Butelli E13, De Angelis M14, Martin C15, Santino A16, Chieppa M. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li. (PMC)
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