Kyle J. Norton
Surgery is a medical practice that uses operative manual and instrumental techniques on a patient to investigate or treat an injury or disease
The aim of the medical procedure is to promote bodily function,
The most common types of surgery in the US
* Appendectomy is the common surgery that removes the appendix in patients with acute inflammation of the appendix due to infection.
* Breast biopsy. A biopsy that removes breast tissue to diagnose cancer.
* Carotid endarterectomy is used to remove the blockage from carotid arteries
* Cataract surgery is to remove the cloudy lens and replace it with a clear artificial lens.
* Cesarean section or c-section helps to deliver a baby by making an incision through the mother's abdomen and uterus.
* Cholecystectomy is a surgery that removes the gallbladder.
The Atlantic General Hospital in examining the benefits and risks of surgery wrote,
"Benefits of having surgery
• Prevention of or improvements to medical conditions caused by a patient's obesity
• Surge in energy
• Increased life expectancy
• Increased self-esteem
• Weight loss
Risks to having surgery:
• A blood clot in a vein (deep venous thrombosis or DVT)
• Bleeding or infection
• Bowel obstruction caused by scar tissue
• Leakage of fluid (if opting for gastric banding)
• Adverse reaction to anesthesia
• Nausea and Vomiting
• Band slippage (if opting for gastric banding)
• Gallstones
• The overall risk of death".
Please make sure that you discuss all the health benefits and risks of having surgery with your surgeon ahead of the operation.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
On finding a natural compound for reducing scar after surgery, researchers investigated the effects of onion extract-based topical gel (Mederma, Merz Pharmaceuticals, Greensboro, NC, USA) that has been marketed as a product to improve scar appearance and texture.
The randomized, double-blinded, split-scar study including 24 patients with new surgical wounds of at least 4 cm in length was divided into two equal portions with each half treated by either onion extract gel or petrolatum ointment at the time of suture removal by applying three times daily for 8 weeks.
By comparing the efficacy between the onion extract gel and a petrolatum-based emollient (Aquaphor, Beiersdorf, Inc., Wilton, CT, USA), researchers at the Harvard Medical School showed that
* According to patients evaluated at 2, 8, and 12 weeks following initiation of treatment and a follow-up telephone interview conducted at least 11 months postoperatively, onion extract gel improved wound healing compared to those of petrolatum-based topical agents.
* According to the paired t-test and the Wilcoxon signed-rank test at the end of the experiment, there was no statistically significant difference (p < .1) between the two treatment groups.
In other words, onion extract-based topical gel demonstrated a similar effect as those of petrolatum ointment but did not improve scar cosmesis or symptomatology.
Petrolatum ointment has been used in standard therapy in the management of postoperative wounds.
Taken together, onion may be considered a remedy in the management of postoperative wounds, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study by Chung VQ1, Kelley L, Marra D, Jiang SB. (PubMed)
(2) Risks & Benefits of Surgery by The Atlantic General Hospital
Tuesday, 24 October 2023
#Tomatoes Modulate Immune Function Associated with the Onset of #Colitis, According to Studies
Kyle J. Norton
Colitis is chronic a condition associated with the inflammation of the large intestine, including the colon, caecum, and rectum.
Colitis can be classified into the microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis and Behcet's colitis(a), according to the Catholic University of the Sacred Heart.
Most common symptoms of colitis are totally depending on the types. However, the general symptoms include
* Adnominal pain and diarrhea
There is a report of a 25-year-old Iranian gentleman who was admitted to the hospital with severe bloody diarrhea and abdominal pain as a result of herbal-induced weight loss effects. On flexible sigmoidoscopy, a continuous length of congested mucosa with multiple small ulcers was seen extending up to the mid-transverse colon, in keeping with ulcerative colitis, according to the study by
Homerton University Hospital NHS Foundation Trust(1)
2. Bleeding per rectum
Acute ischaemic colitis (AIC) is being increasingly recognized as an uncommon cause of abdominal pain associated with fresh bleeding per rectum and diarrhea, according to the study by University Central Hospital(2).
3. Distention with bloody diarrhea
The typical clinical presentation is acute sudden abdominal pain and distention with bloody diarrhea(3).
4. Abdominal bloating and flatulence
In the study to estimate the prevalence of microscopic colitis and SIBO in patients with IBS, to evaluate the symptoms and the efficacy of treatment found that out of the 132 patients initially diagnosed with IBS 3% (n=4) had microscopic colitis and 43.9% (n=58) had SIBO. Diarrhea was the main symptom in patients with microscopic colitis and SIBO (p=0.041), while abdominal pain, abdominal bloating, and flatulence were prominent in IBS patients (p=0.042; p=0.039; p=0.048)(4).
5. Changes in bowel habits
Abdominal pain, bloating, early satiety, and changes in bowel habits are common presenting symptoms in individuals with functional GI disorders(5).
6. Fever and severe dehydration
There is a report of a 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea, and severe dehydration. He was on po.48 mg methylprednisolone and 3 g mesalazine daily and has recently finished taking clarithromycin for Campylobacter jejuni infection(6).
7. Urgency
The study to examine the differing perspectives and perceptual gaps relating to ulcerative colitis (UC) symptoms and their management between patients and healthcare professionals (HCPs), indicated that fifty-five percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life over the same period. Patients ranked urgency and pain as the most bothersome symptoms(7)
8. Other symptoms
There is a report of a case of a 51-year-old Caucasian male who was evaluated for abdominal pain, elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea as a result of granulomatous enterocolitis. due to Sarcoidosis(8). Another study conducted by Anhui University of Traditional Chinese Medicine, with rats in the model group, showed lethargy, poor appetite, loss of energy, diarrhea, and bloody stool(9).
If you have experienced some of the aforementioned symptoms persistently with no signs of stopping, please make sure you check with your doctor to rule out the possibility of colitis.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding healthy foods for the treatment of colitis, researchers examined the impact of tomato lycopene extract (TLE) on intestinal inflammation.
The study included mice lipopolysaccharide (LPS)-induced innate signaling and experimental colitis fed a diet containing 0.5 and 2% TLE or isoflavone free control (AIN-76).
According to the tested assays, TLE blocked LPS-induced IkappaBalpha degradation and RelA translocation associated with the onset of colitis by blocking the inhibition of the protein involved in cytokine production.
Furthermore, MIP-2, a small cytokine mRNA accumulation in IEC-18 cells, and pro-inflammatory cytokine Interleukin 12 (IL-12) induced by LPS were inhibited by the injection of TLE.
Moreover, the application of TLE also increased the expression of anti-inflammatory cytokines IL-6, TNF-alpha, a regulator of inflammation, and MCP-1 mRNA associated with macrophage recruitment in the colon of TLE-fed subjects.
The results strongly suggested that tomato extract inhibited colitis in mice through its modulatory of immune and inflammatory activity.
Taken together, tomato may be considered a dietary supplement for the prevention and treatment of colitis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice by Joo YE1, Karrasch T, Mühlbauer M, Allard B, Narula A, Herfarth HH, Jobin C. (PubMed)
(2) Colitis - Types and Symptoms by Kyle J. Norton
Colitis is chronic a condition associated with the inflammation of the large intestine, including the colon, caecum, and rectum.
Colitis can be classified into the microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis and Behcet's colitis(a), according to the Catholic University of the Sacred Heart.
Most common symptoms of colitis are totally depending on the types. However, the general symptoms include
* Adnominal pain and diarrhea
There is a report of a 25-year-old Iranian gentleman who was admitted to the hospital with severe bloody diarrhea and abdominal pain as a result of herbal-induced weight loss effects. On flexible sigmoidoscopy, a continuous length of congested mucosa with multiple small ulcers was seen extending up to the mid-transverse colon, in keeping with ulcerative colitis, according to the study by
Homerton University Hospital NHS Foundation Trust(1)
2. Bleeding per rectum
Acute ischaemic colitis (AIC) is being increasingly recognized as an uncommon cause of abdominal pain associated with fresh bleeding per rectum and diarrhea, according to the study by University Central Hospital(2).
3. Distention with bloody diarrhea
The typical clinical presentation is acute sudden abdominal pain and distention with bloody diarrhea(3).
4. Abdominal bloating and flatulence
In the study to estimate the prevalence of microscopic colitis and SIBO in patients with IBS, to evaluate the symptoms and the efficacy of treatment found that out of the 132 patients initially diagnosed with IBS 3% (n=4) had microscopic colitis and 43.9% (n=58) had SIBO. Diarrhea was the main symptom in patients with microscopic colitis and SIBO (p=0.041), while abdominal pain, abdominal bloating, and flatulence were prominent in IBS patients (p=0.042; p=0.039; p=0.048)(4).
5. Changes in bowel habits
Abdominal pain, bloating, early satiety, and changes in bowel habits are common presenting symptoms in individuals with functional GI disorders(5).
6. Fever and severe dehydration
There is a report of a 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea, and severe dehydration. He was on po.48 mg methylprednisolone and 3 g mesalazine daily and has recently finished taking clarithromycin for Campylobacter jejuni infection(6).
7. Urgency
The study to examine the differing perspectives and perceptual gaps relating to ulcerative colitis (UC) symptoms and their management between patients and healthcare professionals (HCPs), indicated that fifty-five percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life over the same period. Patients ranked urgency and pain as the most bothersome symptoms(7)
8. Other symptoms
There is a report of a case of a 51-year-old Caucasian male who was evaluated for abdominal pain, elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea as a result of granulomatous enterocolitis. due to Sarcoidosis(8). Another study conducted by Anhui University of Traditional Chinese Medicine, with rats in the model group, showed lethargy, poor appetite, loss of energy, diarrhea, and bloody stool(9).
If you have experienced some of the aforementioned symptoms persistently with no signs of stopping, please make sure you check with your doctor to rule out the possibility of colitis.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding healthy foods for the treatment of colitis, researchers examined the impact of tomato lycopene extract (TLE) on intestinal inflammation.
The study included mice lipopolysaccharide (LPS)-induced innate signaling and experimental colitis fed a diet containing 0.5 and 2% TLE or isoflavone free control (AIN-76).
According to the tested assays, TLE blocked LPS-induced IkappaBalpha degradation and RelA translocation associated with the onset of colitis by blocking the inhibition of the protein involved in cytokine production.
Furthermore, MIP-2, a small cytokine mRNA accumulation in IEC-18 cells, and pro-inflammatory cytokine Interleukin 12 (IL-12) induced by LPS were inhibited by the injection of TLE.
Moreover, the application of TLE also increased the expression of anti-inflammatory cytokines IL-6, TNF-alpha, a regulator of inflammation, and MCP-1 mRNA associated with macrophage recruitment in the colon of TLE-fed subjects.
The results strongly suggested that tomato extract inhibited colitis in mice through its modulatory of immune and inflammatory activity.
Taken together, tomato may be considered a dietary supplement for the prevention and treatment of colitis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice by Joo YE1, Karrasch T, Mühlbauer M, Allard B, Narula A, Herfarth HH, Jobin C. (PubMed)
(2) Colitis - Types and Symptoms by Kyle J. Norton
#ManukaHoney Inhibits Oxidativestress markers Associated with the Risk of Acute and Chronic Inflammatory Diseases, Researchers Find
Kyle J. Norton
Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulate the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms that may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory functions also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frame of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
In finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "The beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 of our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the study, the Manuka honey-treated group displayed a significantly decreased ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.
Manuka honey treated group also showed increased levels of antioxidant enzymes which were suppressed by the injection of ethanol to an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker, and plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "Manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and non-enzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken together, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulate the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms that may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory functions also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frame of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
In finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "The beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 of our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the study, the Manuka honey-treated group displayed a significantly decreased ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.
Manuka honey treated group also showed increased levels of antioxidant enzymes which were suppressed by the injection of ethanol to an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker, and plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "Manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and non-enzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken together, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
Monday, 23 October 2023
#Herbal #Bilberry Induces #Atheroprotection by Protecting Against Plaque Accumulation on the Arterial Walls, According to Studies
Kyle J. Norton
Atherosclerosis is a condition associated with the accumulated plaque on the arterial wall. Over time the condition can cause stiffening and hardening of the arterial, leading to cardiovascular disease.
Atheroprotection is an action that reduces the plaque buildup on the arterial wall. In other words, anything, including the use of substances such as herbal remedy that prevents the blockage or narrowing of the arteries is considered to process atheroprotective effects.
Although plaque is formed by substances found in the bloodstream, most cases of atherosclerosis are also associated with the amount of cholesterol that normally returns to the liver in healthy individuals remaining in the blood due to low levels of good cholesterol (HDL) or overexpression of bad cholesterol (LDL).
In other words, an unhealthy ratio of low and high-density lipoprotein is also one of the major risk factors for atherosclerosis. the healthy ratio of blood cholesterol is any number that is less than 4 (LDL)/ 1 )HDL)
Dr. Ilaria Zanotti, the lead scientist in the investigation of atheroprotective effects of (poly) phenols wrote, "Epidemiological studies have demonstrated that dietary intake of (poly)phenols from nuts, coffee, cocoa, grapes, and berries may protect against the development of atherosclerosis".
And, "... recently emerging data suggest mechanisms by which (poly)phenolic substances can modulate cellular lipid metabolism, thereby mitigating atherosclerotic plaque formation".
The results strongly suggested a healthy diet including nuts, coffee, cocoa, grapes, and berries may have a profound effect on the prevention of atherosclerosis.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
With an aim to find a potent ingredient that processes atheroprotective effects, researchers assessed the results of the intake of bilberry foods associated with a reduced risk of cardiovascular diseases from the previous study.
2 bilberry extracts included one rich in anthocyanins extracted from untreated bilberries (BE) and a second one extracted from yeast-fermented bilberries (FBE).
Atherosclerosis-induced apolipoprotein E-deficient mice (apo E(-/-)) received for 16 weeks a diet supplemented with 0.02% of either BE or FBE.
According to the measurement of atherosclerotic plaque area, administration of both supplementations bilberry extracts led to significant inhibition of plaque development, without affecting on oxidative stress parameters or lipid profiles.
The results surprisingly suggested bilberry supplement inhibited atherosclerotic development through other mechanisms unrelated to inflammation and lipoproteins.
Compared to BE, FBE showed better protection against plaque accumulation on the arterial walls.
The finding firmly showed that the fermentation must have generated new bioactive compounds that are found in the BE extracts.
In other words, other compounds found in bilberry fermentation are more effective in attenuating the progression of atherosclerotic lesions.
Taken together, bilberry, particularly bilberry fermentation processed abundantly bioactive compounds anthocyanins may be considered function remedies for the prevention and treatment of atherosclerosis, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Atheroprotective effects of bilberry extracts in apo E-deficient mice by Mauray A1, Milenkovic D, Besson C, Caccia N, Morand C, Michel F, Mazur A, Scalbert A, Felgines C. (PubMed)
(2) Atheroprotective effects of (poly) phenols: A focus on cell cholesterol metabolism by Ilaria Zanotti, Margherita Dall'Asta, Pedro Mena, and Laura Mele ( Research Gate)
Atherosclerosis is a condition associated with the accumulated plaque on the arterial wall. Over time the condition can cause stiffening and hardening of the arterial, leading to cardiovascular disease.
Atheroprotection is an action that reduces the plaque buildup on the arterial wall. In other words, anything, including the use of substances such as herbal remedy that prevents the blockage or narrowing of the arteries is considered to process atheroprotective effects.
Although plaque is formed by substances found in the bloodstream, most cases of atherosclerosis are also associated with the amount of cholesterol that normally returns to the liver in healthy individuals remaining in the blood due to low levels of good cholesterol (HDL) or overexpression of bad cholesterol (LDL).
In other words, an unhealthy ratio of low and high-density lipoprotein is also one of the major risk factors for atherosclerosis. the healthy ratio of blood cholesterol is any number that is less than 4 (LDL)/ 1 )HDL)
Dr. Ilaria Zanotti, the lead scientist in the investigation of atheroprotective effects of (poly) phenols wrote, "Epidemiological studies have demonstrated that dietary intake of (poly)phenols from nuts, coffee, cocoa, grapes, and berries may protect against the development of atherosclerosis".
And, "... recently emerging data suggest mechanisms by which (poly)phenolic substances can modulate cellular lipid metabolism, thereby mitigating atherosclerotic plaque formation".
The results strongly suggested a healthy diet including nuts, coffee, cocoa, grapes, and berries may have a profound effect on the prevention of atherosclerosis.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
With an aim to find a potent ingredient that processes atheroprotective effects, researchers assessed the results of the intake of bilberry foods associated with a reduced risk of cardiovascular diseases from the previous study.
2 bilberry extracts included one rich in anthocyanins extracted from untreated bilberries (BE) and a second one extracted from yeast-fermented bilberries (FBE).
Atherosclerosis-induced apolipoprotein E-deficient mice (apo E(-/-)) received for 16 weeks a diet supplemented with 0.02% of either BE or FBE.
According to the measurement of atherosclerotic plaque area, administration of both supplementations bilberry extracts led to significant inhibition of plaque development, without affecting on oxidative stress parameters or lipid profiles.
The results surprisingly suggested bilberry supplement inhibited atherosclerotic development through other mechanisms unrelated to inflammation and lipoproteins.
Compared to BE, FBE showed better protection against plaque accumulation on the arterial walls.
The finding firmly showed that the fermentation must have generated new bioactive compounds that are found in the BE extracts.
In other words, other compounds found in bilberry fermentation are more effective in attenuating the progression of atherosclerotic lesions.
Taken together, bilberry, particularly bilberry fermentation processed abundantly bioactive compounds anthocyanins may be considered function remedies for the prevention and treatment of atherosclerosis, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Atheroprotective effects of bilberry extracts in apo E-deficient mice by Mauray A1, Milenkovic D, Besson C, Caccia N, Morand C, Michel F, Mazur A, Scalbert A, Felgines C. (PubMed)
(2) Atheroprotective effects of (poly) phenols: A focus on cell cholesterol metabolism by Ilaria Zanotti, Margherita Dall'Asta, Pedro Mena, and Laura Mele ( Research Gate)
#Herbal #AshwagandhaRoot Extract Enhances Cardiorespiratory Endurance, and Quality of Life, Researchers Suggest
Kyle J. Norton
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to nourish the body tissues and organs.
Cardiorespiratory endurance is a measurement of how well your heart, lungs, and muscles work over an extended period of time of physical activity.
Participating in a program of regular aerobic exercise has been found to improve cardiorespiratory endurance in athletes.
In other words, healthy individuals with optimal cardiorespiratory endurance have been found to benefit from reducing the risk of heart disease, lung cancer, type 2 diabetes, stroke, and other diseases.
Furthermore, cardiorespiratory fitness also improves lung and heart condition and increases feelings of well-being.
An article posted in the Medical News Today regarding the health benefits of cardiorespiratory fitness wrote, "Scientific research also suggests some other potential health benefits from having an improved cardiorespiratory endurance" and "For example:
A 2017 study suggests that people with higher cardiorespiratory endurance are less likely to develop high blood pressure than those with lower cardiorespiratory endurance.
In a 2015 study, researchers found a positive correlation between cardiorespiratory endurance levels and multitasking performance among adults aged between 59 and 80 years.
Improving cardiorespiratory endurance may decrease the risk of coronary heart disease and all-cause mortality, according to a 2015 study".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In finding a natural ingredient for the improvement of health and fitness, researchers examined the clinical efficacy of herbal Ashwagandha on cardiovascular endurance and physical performance.
According to the results from a prospective, double-blind, randomized, and placebo-controlled study included 50 healthy male/female athletic adults,
* Participants who received KSM-66 Ashwagandha showed a greater increase from baseline in the mean peak physical exertion (VO2 max compared to placebo (n = 25) at 8 weeks (4.91 and 1.42, respectively) and at 12 weeks.
* Furthermore, at week 12, the Ashwagandha group showed an improvement in the quality of life (QOL) scores for all subdomains significantly, compared to the placebo (P < 0.05).
In other words, Ashwagandha root extract enhances cardiorespiratory endurance and improves QOL in healthy athletic adults.
Taken together, Ashwagandha may be considered a supplement for the promotion of cardiovascular endurance and physical performance in healthy exercisers, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults by Bakhtiar Choudhary, A. Shetty,1 and Deepak G.
Langade. (PMC)
(2) What to know about cardiorespiratory endurance by Gerhard Whitworth, R.N. on June 17, 2019 — Written by Jamie Eske. (Medical News Today)
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to nourish the body tissues and organs.
Cardiorespiratory endurance is a measurement of how well your heart, lungs, and muscles work over an extended period of time of physical activity.
Participating in a program of regular aerobic exercise has been found to improve cardiorespiratory endurance in athletes.
In other words, healthy individuals with optimal cardiorespiratory endurance have been found to benefit from reducing the risk of heart disease, lung cancer, type 2 diabetes, stroke, and other diseases.
Furthermore, cardiorespiratory fitness also improves lung and heart condition and increases feelings of well-being.
An article posted in the Medical News Today regarding the health benefits of cardiorespiratory fitness wrote, "Scientific research also suggests some other potential health benefits from having an improved cardiorespiratory endurance" and "For example:
A 2017 study suggests that people with higher cardiorespiratory endurance are less likely to develop high blood pressure than those with lower cardiorespiratory endurance.
In a 2015 study, researchers found a positive correlation between cardiorespiratory endurance levels and multitasking performance among adults aged between 59 and 80 years.
Improving cardiorespiratory endurance may decrease the risk of coronary heart disease and all-cause mortality, according to a 2015 study".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In finding a natural ingredient for the improvement of health and fitness, researchers examined the clinical efficacy of herbal Ashwagandha on cardiovascular endurance and physical performance.
According to the results from a prospective, double-blind, randomized, and placebo-controlled study included 50 healthy male/female athletic adults,
* Participants who received KSM-66 Ashwagandha showed a greater increase from baseline in the mean peak physical exertion (VO2 max compared to placebo (n = 25) at 8 weeks (4.91 and 1.42, respectively) and at 12 weeks.
* Furthermore, at week 12, the Ashwagandha group showed an improvement in the quality of life (QOL) scores for all subdomains significantly, compared to the placebo (P < 0.05).
In other words, Ashwagandha root extract enhances cardiorespiratory endurance and improves QOL in healthy athletic adults.
Taken together, Ashwagandha may be considered a supplement for the promotion of cardiovascular endurance and physical performance in healthy exercisers, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults by Bakhtiar Choudhary, A. Shetty,1 and Deepak G.
Langade. (PMC)
(2) What to know about cardiorespiratory endurance by Gerhard Whitworth, R.N. on June 17, 2019 — Written by Jamie Eske. (Medical News Today)
#Cranberry #Extract Disrupts Biofilm Structural Architecture That Causes #CandidaAlbicans Overgrowth, Researchers Find
Kyle J. Norton
The fungus is a class of primitive organisms, including mushrooms, mold, and mildew found in the air, in the soil, on plants, and in water.
Fungi reproduce through tiny spores in the air if you inhale the spores, it may spread to cause fungal infection, often starting in the lungs or on the skin.
Similar to other bacteria, there are millions of different fungal species on Earth, but only about 300 are known to infect people.
Conventionally, fungal infection is treated with antibiotics, including topical antifungal ointments or oral medications, depending on the severity of the disease.
Candida is a class of yeasts that cause fungal infections worldwide.
Candida albicans is a member of a large group of an organism whose cells contain complex structures enclosed within the membranes, including yeast and mold that live among the gut flora in the human mouth and gastrointestinal tract.
Under normal circumstances, Candida albicans do not cause harm to humans, but overgrowth results in candidiasis.
Oral candidiasis is an oral condition infected by the fungal C. albicans found mostly in people with a weakened immune system including patients who are taking the immune-suppressive medicine.
Biofilms are microbial communities in which cells stick to each other and often also to a surface.
Symptoms of oral Candida overgrowth are worse on a damp day, including persistent drowsiness, lack of coordination, headaches, mood swings, loss of balance, rashes, bad breath, dry mouth, and postnasal drip.
There are many risk factors associated with Candida overgrowth including medical conditions that cause a weakened immune system, inhalant medicine, low levels of stomach acids, and pregnancy.
Some researchers suggested aging may be one of the major risk factors that cause Candida overgrowth
Dr. Aikaterini Flevari, the lead scientist said, "Candida species remain the most important cause of opportunistic infections worldwide, affecting predominantly patients over 65 years old, while they are considered to be the fourth most common cause of nosocomial bloodstream infections".
And, "The rapidly growing elderly population has specific physiological characteristics, which makes it susceptible to colonization and subsequent infection due to Candida species".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of Candida albicans, researchers examined the effects of polyphenol-rich cranberry extracts on dual-species Streptococcus mutans-Candida. albicans biofilms.
On S. mutans-C. albicans biofilms grown on saliva-coated hydroxyapatite discs (s-HA) mounted on the high-throughput Amsterdam Active Attachment model, cranberry extracts(ACE)/vehicle control was applied at the five minutes just before biofilm growth and subsequently, for similar exposure times, after 12 hours and 24 hours of biofilm growth.
Based on the analysis, the treatment of ACE at doses of 500 to 1,000 μg/mL showed significant reductions in acidogenicity and metabolic activity, compared to the control.
Biovolumes of the EPS (P=0.003) and microbial biofilm components associated with the overgrowth of Candida albicans were significantly decreased by the application of ACE.
According to the qualitative assessment of confocal biofilm images, cranberry extract disrupted biofilm structural architecture that causes Candida albicans.
Moreover, ACE showed significantly fewer S. mutans (P=0.006) and C. albicans (P=0.036) compared to control.
Based on the findings, researchers aid, "Cranberry extracts inhibited cariogenic virulence properties of S. mutans-C. albicansdual-species biofilms in an in vitro model".
Taken together, cranberry may be considered a remedy for the treatment of Candida albicans,, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Polyphenol-Rich Cranberry Extracts Modulate Virulence of Streptococcus mutans-Candida albicans Biofilms Implicated in the Pathogenesis of Early Childhood Caries by Philip N1, Leishman SJ2, Bandara H3, Walsh LJ. (PubMed)
(2) Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms by Sundararajan A1, Rane HS2, Ramaraj T1, Sena J1, Howell AB3, Bernardo SM4, Schilkey FD1, Lee SA. (PubMed)
(3) Treatment of invasive candidiasis in the elderly: a review by Aikaterini Flevari,1 Maria Theodorakopoulou,1 Aristea Velegraki,2 Apostolos Armaganidis,1 and George Dimopoulos. (PMC)
The fungus is a class of primitive organisms, including mushrooms, mold, and mildew found in the air, in the soil, on plants, and in water.
Fungi reproduce through tiny spores in the air if you inhale the spores, it may spread to cause fungal infection, often starting in the lungs or on the skin.
Similar to other bacteria, there are millions of different fungal species on Earth, but only about 300 are known to infect people.
Conventionally, fungal infection is treated with antibiotics, including topical antifungal ointments or oral medications, depending on the severity of the disease.
Candida is a class of yeasts that cause fungal infections worldwide.
Candida albicans is a member of a large group of an organism whose cells contain complex structures enclosed within the membranes, including yeast and mold that live among the gut flora in the human mouth and gastrointestinal tract.
Under normal circumstances, Candida albicans do not cause harm to humans, but overgrowth results in candidiasis.
Oral candidiasis is an oral condition infected by the fungal C. albicans found mostly in people with a weakened immune system including patients who are taking the immune-suppressive medicine.
Biofilms are microbial communities in which cells stick to each other and often also to a surface.
Symptoms of oral Candida overgrowth are worse on a damp day, including persistent drowsiness, lack of coordination, headaches, mood swings, loss of balance, rashes, bad breath, dry mouth, and postnasal drip.
There are many risk factors associated with Candida overgrowth including medical conditions that cause a weakened immune system, inhalant medicine, low levels of stomach acids, and pregnancy.
Some researchers suggested aging may be one of the major risk factors that cause Candida overgrowth
Dr. Aikaterini Flevari, the lead scientist said, "Candida species remain the most important cause of opportunistic infections worldwide, affecting predominantly patients over 65 years old, while they are considered to be the fourth most common cause of nosocomial bloodstream infections".
And, "The rapidly growing elderly population has specific physiological characteristics, which makes it susceptible to colonization and subsequent infection due to Candida species".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of Candida albicans, researchers examined the effects of polyphenol-rich cranberry extracts on dual-species Streptococcus mutans-Candida. albicans biofilms.
On S. mutans-C. albicans biofilms grown on saliva-coated hydroxyapatite discs (s-HA) mounted on the high-throughput Amsterdam Active Attachment model, cranberry extracts(ACE)/vehicle control was applied at the five minutes just before biofilm growth and subsequently, for similar exposure times, after 12 hours and 24 hours of biofilm growth.
Based on the analysis, the treatment of ACE at doses of 500 to 1,000 μg/mL showed significant reductions in acidogenicity and metabolic activity, compared to the control.
Biovolumes of the EPS (P=0.003) and microbial biofilm components associated with the overgrowth of Candida albicans were significantly decreased by the application of ACE.
According to the qualitative assessment of confocal biofilm images, cranberry extract disrupted biofilm structural architecture that causes Candida albicans.
Moreover, ACE showed significantly fewer S. mutans (P=0.006) and C. albicans (P=0.036) compared to control.
Based on the findings, researchers aid, "Cranberry extracts inhibited cariogenic virulence properties of S. mutans-C. albicansdual-species biofilms in an in vitro model".
Taken together, cranberry may be considered a remedy for the treatment of Candida albicans,, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Polyphenol-Rich Cranberry Extracts Modulate Virulence of Streptococcus mutans-Candida albicans Biofilms Implicated in the Pathogenesis of Early Childhood Caries by Philip N1, Leishman SJ2, Bandara H3, Walsh LJ. (PubMed)
(2) Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms by Sundararajan A1, Rane HS2, Ramaraj T1, Sena J1, Howell AB3, Bernardo SM4, Schilkey FD1, Lee SA. (PubMed)
(3) Treatment of invasive candidiasis in the elderly: a review by Aikaterini Flevari,1 Maria Theodorakopoulou,1 Aristea Velegraki,2 Apostolos Armaganidis,1 and George Dimopoulos. (PMC)
#Healthyfood #WhiteButtonMushroom Inhibits the Risk of Fatty Liver Disease, According to Studies
Kyle J. Norton
White button mushrooms may have a protective effect against the onset and treatment of nonalcoholic liver disease, some scientists suggested.
Fatty liver or hepatic steatosis is a disease caused by the buildup of fat in the liver. If the fat in your liver is over 5 percent proportional to the liver cells, you are considered to have the early stage of fatty liver disease.
According to the American liver foundation, the fatty liver is the most common disease in the US, affecting over affecting around 25 % of the population. The disease is most common in the age group between 40 and 60.
The common diseases associated with the onset of the nonalcoholic fatty liver disease include obesity hyperlipidemia, or high levels of fats in the blood, especially high triglycerides, diabetes, and genetic inheritance.
However, some researchers also found that long-term use of certain medications is the prevalent risk factor for fatty liver such as rapid weight loss side effects of certain medications, including methotrexate (Trexall), tamoxifen (Nolvadex), amiodarone (Pacerone), and valproic acid (Depakote).
Can the nonalcoholic fatty liver disease be prevented? Dr. William Nseir, the lead author in the study " Role of diet and lifestyle changes in nonalcoholic fatty liver disease", wrote, "there is no drug therapy that can be formulated for treating NAFLD. A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD management" and
"NAFLD patients, whether obese or not, should be educated that a healthy diet and physical activity have benefits beyond weight reduction".
The result suggested that if you have followed a healthy diet high in fruits and vegetables, whole grains, and low in saturated and trans fat, red meat, and processed food and lifestyle accompanied by moderate exercise, your risk of nonalcoholic fatty liver disease is closed to zero.
If you are experiencing the symptoms of a persistently enlarged fluid-filled abdomen, jaundice of the skin and eyes, confusion, and abnormal bleeding, please check with your doctor to rule out the possibility of fatty liver disease.
Mushroom is a standard name for white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,
It is a genus A. Muscaria and belongs to the family Amanitaceae and has been cultivated in many cultures all over the world for food and health benefits.
The chemical constituents of white button mushrooms include
Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil, and D-mannitol.
In the concerns of low estrogen production in the risk of nonalcoholic fatty liver disease in menopause women, researchers at the cellular team at the Beckman Research Institute of the City of Hope launched an investigation to examine the effects of white mushrooms in the groups of ovariectomized mice (a model of postmenopausal women).
Selected OVX mice were fed a high-fat diet supplemented with WBM powder before injection of white button mushroom to induce fatty disease patterns.
Application of white button mushroom (WBM) exerted a significant protective effect against liver steatosis in ovariectomized (OVX) mice.
Dietary WBM intake significantly lowered liver weight and hepatic injury markers in OVX mice.
The pathological examination also suggested that WBM lowers fat accumulation in tissue in the livers of mice.
Furthermore, the glucose clearance ability of tested mice also improved substantially compared to the untreated mice group.
According to the microarray analysis, genes associated to the fatty acid biosynthesis pathway, particularly the genes for fatty acid synthetase (Fas), a major determinant of the maximal hepatic capacity to generate fatty acids by de novo lipogenesis and fatty acid elongase 6 (Elovl6) which plays a key role in fat synthesis were down-regulated (reduced function).
Additionally, in vivo, the down-regulation of the expression of FAS and ELOVL6 in the HepG2 cell line by WBM extract was attributed to the inhibition of Liver X receptor (LXR) signaling and it's downstream transcriptional factor SREBP1c.
Where Liver X receptors (LXRs) are important regulators of cholesterol and fatty acid and SREBP-1c is associated with fatty liver and increased visceral fat mass.
The finding indicated that WBM is protective against hepatic steatosis and NAFLD in OVX mice as a model for postmenopausal women.
The study was published on October 25 by the US National Library of Medicine and National Institutes of Health. You can view the publication by clicking the link in the resources,
Taken together, white button mushrooms may be considered a functional food for the prevention and treatment of nonalcoholic fatty liver disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women by Kanaya N1, Kubo M, Liu Z, Chu P, Wang C, Yuan YC, Chen S.(PubMed)
(2) Role of diet and lifestyle changes in nonalcoholic fatty liver disease by William Nseir, Elias Hellou, and Nimer Assy. (PubMed)
White button mushrooms may have a protective effect against the onset and treatment of nonalcoholic liver disease, some scientists suggested.
Fatty liver or hepatic steatosis is a disease caused by the buildup of fat in the liver. If the fat in your liver is over 5 percent proportional to the liver cells, you are considered to have the early stage of fatty liver disease.
According to the American liver foundation, the fatty liver is the most common disease in the US, affecting over affecting around 25 % of the population. The disease is most common in the age group between 40 and 60.
The common diseases associated with the onset of the nonalcoholic fatty liver disease include obesity hyperlipidemia, or high levels of fats in the blood, especially high triglycerides, diabetes, and genetic inheritance.
However, some researchers also found that long-term use of certain medications is the prevalent risk factor for fatty liver such as rapid weight loss side effects of certain medications, including methotrexate (Trexall), tamoxifen (Nolvadex), amiodarone (Pacerone), and valproic acid (Depakote).
Can the nonalcoholic fatty liver disease be prevented? Dr. William Nseir, the lead author in the study " Role of diet and lifestyle changes in nonalcoholic fatty liver disease", wrote, "there is no drug therapy that can be formulated for treating NAFLD. A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD management" and
"NAFLD patients, whether obese or not, should be educated that a healthy diet and physical activity have benefits beyond weight reduction".
The result suggested that if you have followed a healthy diet high in fruits and vegetables, whole grains, and low in saturated and trans fat, red meat, and processed food and lifestyle accompanied by moderate exercise, your risk of nonalcoholic fatty liver disease is closed to zero.
If you are experiencing the symptoms of a persistently enlarged fluid-filled abdomen, jaundice of the skin and eyes, confusion, and abnormal bleeding, please check with your doctor to rule out the possibility of fatty liver disease.
Mushroom is a standard name for white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,
It is a genus A. Muscaria and belongs to the family Amanitaceae and has been cultivated in many cultures all over the world for food and health benefits.
The chemical constituents of white button mushrooms include
Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil, and D-mannitol.
In the concerns of low estrogen production in the risk of nonalcoholic fatty liver disease in menopause women, researchers at the cellular team at the Beckman Research Institute of the City of Hope launched an investigation to examine the effects of white mushrooms in the groups of ovariectomized mice (a model of postmenopausal women).
Selected OVX mice were fed a high-fat diet supplemented with WBM powder before injection of white button mushroom to induce fatty disease patterns.
Application of white button mushroom (WBM) exerted a significant protective effect against liver steatosis in ovariectomized (OVX) mice.
Dietary WBM intake significantly lowered liver weight and hepatic injury markers in OVX mice.
The pathological examination also suggested that WBM lowers fat accumulation in tissue in the livers of mice.
Furthermore, the glucose clearance ability of tested mice also improved substantially compared to the untreated mice group.
According to the microarray analysis, genes associated to the fatty acid biosynthesis pathway, particularly the genes for fatty acid synthetase (Fas), a major determinant of the maximal hepatic capacity to generate fatty acids by de novo lipogenesis and fatty acid elongase 6 (Elovl6) which plays a key role in fat synthesis were down-regulated (reduced function).
Additionally, in vivo, the down-regulation of the expression of FAS and ELOVL6 in the HepG2 cell line by WBM extract was attributed to the inhibition of Liver X receptor (LXR) signaling and it's downstream transcriptional factor SREBP1c.
Where Liver X receptors (LXRs) are important regulators of cholesterol and fatty acid and SREBP-1c is associated with fatty liver and increased visceral fat mass.
The finding indicated that WBM is protective against hepatic steatosis and NAFLD in OVX mice as a model for postmenopausal women.
The study was published on October 25 by the US National Library of Medicine and National Institutes of Health. You can view the publication by clicking the link in the resources,
Taken together, white button mushrooms may be considered a functional food for the prevention and treatment of nonalcoholic fatty liver disease.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women by Kanaya N1, Kubo M, Liu Z, Chu P, Wang C, Yuan YC, Chen S.(PubMed)
(2) Role of diet and lifestyle changes in nonalcoholic fatty liver disease by William Nseir, Elias Hellou, and Nimer Assy. (PubMed)
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