#Ginger #Extract Processes Antibiofilm Formation Associated with a Reduced Risk of Infectious Diseases, Reserachers Show

Kyle J. Norton

Scientists may have a kitchen remedy that processes the potential to improve the immune function against infection, some studies suggested.

A biofilm is a system that can be adapted internally to environmental conditions by its inhabitants. In other words, biofilm-forming from bacteria is one of the common forms of bacterial infection affecting up to 80% of human bacterial infections.

In biology, biofilm is used by bacteria as a natural defense mechanism of bacteria to survive under harsh environments, by attaching to a solid surface in a large community, including the skin, teeth, and mucosa.

Bacterial initiate biofilm formation with an aim to greatly enhance survival in hosts and cause chronic infections, leading to long-term inflammation and tissue damage.

The formation of a biofilm of bacteria may go through 2 stages, the adhesion phase is the stage in the bacteria attach to the surface or accumulate on a surface, After the adhesion phase, the bacteria enter the colonial phase, where the bacteria continue to grow, leading to the formation of dense bacterial aggregates.

Dr. Li XH, the lead scientist in examining the new anti-biofilm agents, said, "In biofilms, microorganisms become much more resistant to antimicrobial treatments, harsh environmental conditions, and host immunity".

And, "Currently, it is believed over 80% of chronic infectious diseases are mediated by biofilms, and it is known that conventional antibiotic medications are inadequate at eradicating this biofilm-mediated infection".

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Scientists on finding a natural compound with anti-biofilm activity for the treatment of microbial infection evaluated the ginger anti-biofilm formation effects.

Injection of ginger exerted a strong inhibition against Pseudomonas aeruginosa PA14 biofilm formation.


The anti-biofilm activity of ginger caused a reduction of 39–56% when the ginger extract was added to the culture.

The ginger extract also decreased the production of extracellular polymeric substances, the fundamental component that determines the physiochemical properties of a biofilm, according to chemical analysis and confocal laser scanning microscopy.

Furthermore, ginger extract formed noticeably less rugose colonies on agar plates containing Congo red and facilitated swarming motility on soft agar plates.

The ginger extract also inhibited biofilm formation in both Gram-positive and Gram-negative bacteria.


The efficacy of ginger extract was attributed to the reduced level of a second messenger, bis-(3′-5′)-cyclic dimeric guanosine monophosphate in the induction of biofilm formation.

Also, surface biofilm cells formed with ginger extract detached more easily with surfactant than did those without ginger extract.

The results strongly support the use of ginger as a broad-spectrum biofilm inhibitor, in the reduction of bacterial biofilm formation, a major cause of serious health problems.

In order to reveal more information about the ginger effect against biofilm formation, researchers examined the bioactive compounds on Candida albicans.

6-gingerol, 8-gingerol, and 6-shogaol effectively inhibited biofilm formation, and 6-shogaol at 10 μg/ml significantly reduced C. Albicans biofilm formation with no harm to the planktonic cell growth.

Moreover, 6-gingerol and 6-shogaol inhibited hyphal growth in embedded colonies and free-living planktonic cells and prevented cell aggregation.


Additionally, 6-gingerol and 6-shogaol reduced C. Albicans virulence in a nematode infection model without causing toxicity at the tested concentrations.

Dr. Jin-Hyung Lee,, the lead scientist wrote in the final report, "These results highlight the anti-biofilm and antivirulence activities of the ginger components, 6-gingerol, and 6-shogaol, against a drug-resistant C. Albicans strain".

Taken altogether, ginger processed with a high amount of bioactive compounds may be considered a functional remedy for the prevention of bacterial infection by inhibiting the biofilm activity of micro pathogens.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Ginger Extract Inhibits Biofilm Formation by Pseudomonas aeruginosa PA14 by Han-Shin Kim and Hee-Deung Park. (PMC)
(2) Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition by Jin-Hyung Lee,1,† Yong-Guy Kim,1,† Pilju Choi,2 Jungyeob Ham,2 Jae Gyu Park,3,* andJintae Lee. (PMC)
(3) Antibiofilm agents: A new perspective for antimicrobial strategy by Li XH1, Lee JH2. (PubMed)

#GreenLeafyVeggies Lower the Risk of Cardiovascular Disease and Cancer, According to Studies

Kyle J. Norton

Bile acids are synthesized by oxidation from cholesterol in the liver, flowing to the gallbladder to aid digestion.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques to build up on the arterial wall, the major cause of heart disease and stroke.

Bile acid-binding is a process that interferes with normal fat digestion and absorption including the prevention of absorption of fat-soluble vitamins such as A, D, E, and K.

In other words, the binding of bile acids (BAs) may have a strong effect on lowering blood cholesterol levels by increasing the excretion of bile acids in the stool and reducing the amount of bile acid returning to the liver.

By inhibiting the levels of bile acid caused by a certain type of liver/bile duct disease such as partial biliary obstruction, levels of cholesterol can be controlled.

Conventionally, the effects of bile acid sequestrants are limited. Low doses of 8 grams/day of Cholestyramine, a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption can lower LDL cholesterol by 10%-15% compared to high doses of 24 grams/day of only 25%.

In other words, bile acid-binding medicines such as Cholestyramine, used alone are less effective, compared to statins in lowering LDL cholesterol.

The most common symptoms associated with the intake of Cholestyramine are constipation, diarrhea, stomach/abdominal pain, bloating, nausea, vomiting, and loss of appetite.

In finding a potential plant that processes anti-high blood cholesterol activity, researchers compared the bile acid-binding potential that lowers the risk of heart disease and cancer of various vegetables.

Compared to Cholestyramine (a cholesterol-lowering, bile acid-binding drug) that was used as the positive control treatment and cellulose as the negative control, researchers found that* Relative to cholestyramine, in vitro bile acid binding on dry matter basis was for the collard greens, kale, and mustard greens, 13%; broccoli, 10%; Brussels sprouts and spinach, 8%; green bell pepper, 7%; and cabbage, 5%.

In other words, collard greens = kale = mustard greens showed the strongest healthy-promoting potential in bile acid-binding compared to the following lesser extent of > broccoli > Brussels sprouts = spinach = green bell pepper > cabbage.

More importantly, steam cooking significantly improved the in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage compared to vegetables raw (uncooked).

More precisely, the Inclusion of steam-cooked collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage in our daily diet may have the potential to improve healthy levels of blood cholesterol.

Collectively, researchers said, "These green/leafy vegetables, when consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer, advance human nutrition research, and improve public health".

Taken together, green leafy veggies may be considered functional foods for lowering blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kahlon TS1, Chiu MC, Chapman MH. (PubMed)

#RapeseedOil Reduces Body Weight and Metabolic Factors Associated with Cardiovascular Risk, According to Studies

Kyle J. Norton

A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverages in a diet as well as the frequency of the foods that are habitually consumed.
The most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine, or local cuisine".

* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, and high salt, and sugar foods.

Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.

The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.

In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes is increased substantially compared to those who have less.

According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.

Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.

Rapeseed, also known as rape, or oilseed rape, is a member of the family Brassicaceae (mustard or cabbage family), cultivated in suitable climate regions for its oil-rich seed for commercial profits.

In finding a potential compound for the prevention of heart disease, researchers at the University of Applied Sciences investigated the effects of a hypoenergetic diet with low energy density (ED) enriched in rapeseed oil-derived n-3 fatty acid α-linolenic acid (ALA), in patients with metabolic syndrome.

The human trial included eighty-one patients with metabolic syndrome randomly assigned to receive either rapeseed oil derived with high MUFA content and an ALA intake of 3.5 g/d on body weight or olive oil diet rich in MUFA but with a low ALA content.

According to the results, after a 6-month dietary intervention, the rapeseed oil and olive oil groups showed a significant in reduced body weight and metabolic factors associated with cardiovascular risk.

In other words, intervention groups with rapeseed oil not only significantly decrease the systolic blood pressure, but also reduce total cholesterol LDL-cholesterol, and insulin levels in patients with metabolic syndrome.


More interestingly, serum triglycerides (TAG) associated with cardiovascular and nonfatty liver disease risk factors were significantly reduced only in the high ALA intake, compared to no effect on the low ALA group.

Based on the findings, researchers said, "Our dietary food pattern with a low ED and high intakes of MUFA and ALA may be a practical approach for long-term dietary treatment in patients with the metabolic syndrome".

Taken together, rapeseed oil may be considered a supplement for the prevention and treatment of metabolic syndrome, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of a rapeseed oil-enriched hypoenergetic diet with a high content of α-linolenic acid on body weight and cardiovascular risk profile in patients with the metabolic syndrome by Baxheinrich A1, Stratmann B, Lee-Barkey YH, Tschoepe D, Wahrburg U. (PubMed)

#Herbal #Angelica Sinensis Inhibits Glioma Cells Growth and Proliferation, According to Studies

Kyle J. Norton

A glioma is a type of brain and spinal cord tumor characterized by the alternation of DNA of the glial cells.
Believe it or not, gliomas have been found to account for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.

Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.

* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.

* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.

Primary glioblastoma is considered the most aggressive cancer that begins within the brain. Cancer may arise de novo, meaning it begins as a Grade IV tumor with no evidence.

According to the statistics, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.

Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, severe headaches, and localized symptoms depending on the location of the tumor.

Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.


In finding a natural ingredient for the prevention and treatment of neurological diseases, scientists examined the inhibitory effects of Angelica polysaccharides (APs), bioactive constituents of Angelica on a glioma cell line.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to tested analysis of both in vitro and in vivo models,
* APs exerted a significant inhibition of the growth and proliferation of U251 cells and induced their apoptosis.

* APs effectively reduced the expression of several cell cycle regulators such as cyclins D1, B, and E in the induction of cell cycle division of the tested cell line.

* APs also inhibited the anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic proteins Bax and cleaved-caspase-3.

* Most importantly, APs inhibited the transforming growth factor (TGF)-β signaling pathway and stimulated the expression of E-cadherin, associated with the inhibition of cell growth.

Based on the results, researchers suggest, " the results indicate that APs attenuate the tumorigenicity of glioma cells and promote their apoptosis by suppressing the TGF-β signaling pathway".

Taken together, Dandelion may be considered a neuroprotective remedy, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo by Zhang WF1, Yang Y1, Li X1, Xu DY1, Yan YL1, Gao Q1, Jia AL1, Duan MH. (PubMed)

#Cinnamon Extract Alleviates Menstrual Pain and Heavy Menstrual Bleeding, Researchers Suggest

Kyle J. Norton

Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacterial levels, to improve reproductive organs, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

Topical use of essential oil extracted from cinnamon may be the next generation whole herb medicine for the prevention and treatment of menstrual pain and heavy menstrual bleeding

According to Eulji University, in the study compared the effect of aromatherapy massage and acetaminophen on menstrual pain in Korean high school girls. the cinnamon treatment group showed a significantly higher reduction of menstrual pain than in the acetaminophen group.


In a randomized, double-blind trial, out of 114, the group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h significantly reduced the severity and duration of pain during menstruation and menstrual bleeding.


In primary dysmenorrhea, cinnamon expressed a significant over-reduction of pain, menstrual bleeding, nausea, and vomiting with primary dysmenorrhea without side effects.

Dr. Marzouk TM., the lead author at Mansoura University said, " ... aromatherapy abdominal massage once daily for seven days prior to menstruation using the essential oils (cinnamon....) is effective in alleviating menstrual pain, its duration, and excessive menstrual bleeding...." and "Aromatherapy can be provided as a nonpharmacological pain relief measure and as a part of nursing care given to girls suffering from dysmenorrhea, or excessive menstrual bleeding".

Further study of the effect of cinnamon extract on symptoms of dysmenorrhea and contractility in some smooth muscles, Dr. Alotaibi M. suggested, that cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy.

Indeed, Cinnamon may be an effective whole herb medicine used for the treatment of menstrual pain. Intake of cinnamon should be taken with care as toxicity is found in case of overdoses.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study by Hur MH1, Lee MS, Seong KY, Lee MK. (PubMed)
(2) Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial by Jaafarpour M1, Hatefi M2, Khani A3, Khajavikhan J4.(PubMed)
(3) The effect of cinnamon on menstrual bleeding and systemic symptoms with primary dysmenorrhea by Jaafarpour M1, Hatefi M2, Najafi F3, Khajavikhan J4, Khani A3.(PubMed)
(4) The effect of aromatherapy abdominal massage on alleviating menstrual pain in nursing students: a prospective randomized cross-over study by Marzouk TM1, El-Nemer AM, Baraka HN.(PubMed)
(5) The effect of cinnamon extract on isolated rat uterine strips by Alotaibi M1.(PubMed)

#Fennel Exerts Neurons Protective and Memory Enhancing Activity by Inhibiting Overexpression of Oxidative Stress, Researchers Find

Kyle J. Norton

Intake of fennel daily and regularly may have a profound and positive effect in enhancing memory, some scientists suggested.
The human brain consists of billions of neurons, some of them were given a special function in storing the event from the past.

In other words, there is a faculty in the human brain in which the mind stores and remembers information.

There are 2 types of memory. Short-term memory (STM) is a temporary storage system that processes the working memory, reacting by taking into information that already happened in the past.

Long-term memories are information collected by the brain that can last for just a few days, or years. Some long-term memories are more important than others.


Memory loss occurs often in the aging population. It is a normal degeneration, however, we can’t take action to slow it down a little.

Some researchers suggested that a change in lifestyle, such as meditation and eating habits such as reduced intake of red meat which has been found to be associated with lipid peroxidation can improve or slow down the risk of memory loss.


Dr. Xian Jiang, the lead author in the evaluation of the consumption of fruit and vegetables in the risk of cognitive impairment and dementia, wrote, "The meta-analysis showed that increased consumption of fruit and vegetables was associated with a significant reduction in the risk of cognitive impairment and dementia (the leading cause of memory loss)".

Risks of cognitive impairment and dementia-inducing memory loss were reduced by approximately 13% for an increment of 100 g per day of fruit and vegetable consumption.

A study that examines the fennel enhancing memory activity in an orogastric tube suggested that administration at doses of 50, 100, and 200 mg/kg body weight, fennel displays a significant effect in enhancing short and long-term memory.

Scientists at the research center, after taking into account all factors, recommended that adding a portion of fennel to the daily diet may improve memory in all aspects.

Fennel (Foeniculum vulgare) is a plant species of the genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.

The herbal medicine has been used in traditional and herbal medicine, like warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

According to the observation of urinary levels of vanillylmandelic acid (VMA), daily administration of F. Vulgare extract (50, 100, and 200 mg/kg body weight) 1 h prior to the induction of stress, exerted significantly altered the stress in reducing central nervous system in the expression of stress hormone production from 395.79 to 347.12, 311.21 and 258.86 μg/kg, receptively.
In comparison to ascorbic acid, fennel extracts treated groups also exhibited potent antioxidant effect by inhibiting lipid peroxidation in both tested rats liver and brain homogenates to a greater extent.

These results suggested that fennel extract may also improve brain function by reducing oxidative stress and lipid peroxidation in the induction of neuron cells cytotoxicity and apoptosis in facilitating plaque accumulation in the neurons, the process has long been found to decrease long-term memory recalled.


In the same period, memory deficits induced by scopolamine (1mg/kg, i.p.) in rats were significantly reversed by F. Vulgare dose-dependently.

Dr. A. E. Bawazirand, the lead author of the research paper said, "F. vulgare may be useful in the management of stress and stress-related disorders on account of its multiple actions such as anti-stress, memory-enhancing and antioxidant effects".

Further analysis of the enhanced memory and intelligence of F. vulgaris, an ayurvedic Rasayana (mixture) served to children as part of their food in Indian traditional medicine, scientists found that ingestion of whole plant extract at doses of 50, 100 and 200 mg/kg exhibits a strong memory-enhancing effect against scopolamine-induced amnesic rats.

Observed by conditioned avoidance response (CAR) technique, group treated with fennel extract of rats through gradually increased administration up to 95% over 7 to 12 days demonstrated a significant increase of percent avoidance due to information feedback from previous experience, compared to control group.

Additionally, fennel extracts showed strong linearly and independently in memory recalled from tested rats.

As Animals received 200 mg/kg body weight of the extract took ten days, while groups treated with 100 and 50 mg/kg doses of the extract required eleven and twelve days, respectively, to reach the point of acquisition.

Importantly, during the period of the experiment, treated rats demonstrated significantly less amnesia, a partial or total loss of memory induced by scopolamine in comparison to the nontreatment group.

Continuously, fennel treatment also produced better retention and recovery of memory deficits in a dose-dependent manner than the vehicle-treated animals.


Dr. Shamkant B. Badgujar, the lead scientist said, "Recovery from scopolamine-induced amnesia in the extract-treated groups took 3–5 days when compared to normal (control) group which took over 6 days".

Some researchers suggested that the neuro memory enhancement of fennel extracts may be attributed by the effective influence as a sedative and the herbal protective effects in the maintenance of brain tissue through directly increase the total content of neurotransmitters in all the tested regions.


Finally, "Fennel is likely to be safe for use as a moderator and enhancer of the functions of the central nervous system by increasing the total content of neurotransmitters and also can be a protection against stress and stress-related diseases such as memory loss, because it contains high amounts of antioxidants", according to the study of "Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology" suggestion.

Taken together, Fennel whole plant and whole plant extracts may be considered as a function in improved memory in all aspects.

These results also reaffirmed the use of fennel as a brain enhancer product by traditional herbal medicine.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.




Sources
(1) The effect of aqueous extracts of Fennel (Foenicul umvulgare Mill) seeds on some neurotransmitters Content and histological structure changing of cerebellar cortexin the brain of male albino rats by A. E. Bawazirand, L. E. Bokhary(Journal of American Science)
(2) Foeniculum vulgare Mill (Umbelliferae) Attenuates Stress and Improves Memory in Wister Rats by S Koppula, H Kumar(Tropical Journal of Pharmaceutical Research)
(5) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)

#Herbal #Bilberry Enhances Short-Term Memory and Prevent Memory Deficits Related to AD, According to Researchers

Kyle J. Norton

Memory impairment is a condition of partial or complete loss of memory, depending on the quality of the neuron that has been affected.

Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.

The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.

In elderly or aging-induced memory loss is associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.

However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.

Dr. Scott E. Kanoski, the lead scientist in the review of the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".

And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".


The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.

With an aim to find a potential ingredient for the treatment of memory impairment researchers investigated the effects of Vaccinium uliginosum L. (bilberry) on the learning and memory impairments induced by amyloid-β protein (AβP) 1-42.

The evaluation included selected ICR Swiss mice divided randomly into 4 groups: the control (Aβ40-1A), control with 5% bilberry group (Aβ40-1B), amyloid β protein 1-42 treated group (Aβ1-42A), and Aβ1-42 with 5% bilberry group (Aβ1-42B).

According to the tested assays, bilberry-added groups showed to decrease in the finding time of the hidden platform, compared to those of escape latencies of AβP to that of Aβ40-1.


Furthermore, the bilberry-added Aβ1-42B group also showed a significant (P<0.05) increase in probe crossing frequency compared to Aβ1-42A.
In the passive avoidance test, bilberry significantly (P<0.05) increased the time of staying in the lighted area compared to AD control.

These results suggested that bilberry improved memory and learning capability in chemically induced Alzheimer's disease in experimental animal models.

In the incidence of degenerative disorders including Alzheimer's disease (AD), rats consumed approximately 3.2 mg kg(-1)day (oral), of the anthocyanins significantly enhanced short-term memory, but not long-term memory in the inhibitory avoidance task.

Moreover, injection of approximately 3.2 mg kg(-1)day (oral), of the anthocyanins also induced an increase in the number of crossings in the first exposure to the open field.

However, in the comparison of the radial maze and elevated plus-maze, lyophilized berries (blueberry, bilberry) improved working memory in the radial maze, with significant differences observed during sessions 1-2 and 4, compared to no effects in the elevated plus-maze task.

The findings strongly indicated the positive effects of administration of lyophilized Vaccinium berries (blueberry, bilberry) and anthocyanin in the prevention of memory deficits related to AD.

Taken together, bilberry-processed abundantly bioactive compound anthocyanin may be considered a functional remedy for the prevention and treatment of memory impairment, pending to the validation of a larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Vaccinium uliginosum L. Improves Amyloid β Protein-Induced Learning and Memory Impairment in Alzheimer's Disease in Mice by Choi YH1, Kwon HS1, Shin SG1, Chung CK. (PubMed)
(2) Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)
(3) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)