Kyle J. Norton
Rhinosinusitis (RS) is a condition associated with the inflammation of the sinuses and nasal cavity.
Sinusitis is an inflammation of the paranasal sinuses that causes a headache as a result of exposure to a cold or flu virus, or an allergic reaction to pollen, mold, dust, or smoke.
Sinusitis affects 37 million people each year.
Other symptoms of RS include nasal congestion or obstruction, facial or dental pain, purulent rhinorrhea, postnasal drainage, headache, and cough.
Some patients may also experience symptoms of fever, fatigue, hyposmia, ear fullness or pressure, voice changes, epiphora, fever, and psychological effects, and fatigue.
If you have some of the above symptoms that last more than 12 weeks, you may have chronic rhinosinusitis,
If you experience some of the aforementioned symptoms without a cold or flu, you may have rhinosinusitis. Conventionally, most cases of bacterial rhinosinusitis (BRS) are treated by antibiotics.
In viral rhinosinusitis (VRS), medication focuses on reducing symptoms and improving quality of life.
Out of many risk factors involved in the onset of the condition, some researchers suggested that people with an immune deficiency may be vulnerable to rhinosinusitis developing.
Dr. Sergio E. Chiarella, the lead scientist wrote, "CRS is a common disease; in those patients with frequent exacerbations or who are refractory to treatment, an immunodeficiency evaluation should be considered. Treatment includes vaccination, antibiotic therapy, immunoglobulin replacement, and surgery".
More precisely, people who are using immune suppressants or weakened and immature immune systems are at an increased risk of rhinosinusitis.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for the treatment of an inflammatory condition associated with the sinuses and nasal cavity, researchers examined the bromelain effects on patients with chronic rhinosinusitis (CRS).
40 patients including 20 patients were given bromelain 500 mg tablet twice daily for 30 days, and 20 controls enrolled in the study.
According to the observation in the turbinate and ethmoid mucosas and in the serum of both groups, bromelain showed significant anti-inflammatory activity in paranasal sinus pathologies.
In other words, the efficacy of bromelain anti-chronic rhinosinusitis was attributed to its function in distribution evenly in the sinuses and nasal cavity.
Taken altogether, bromelain may be considered supplement for the prevention and treatment of chronic rhinosinusitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis by Passali D1, Passali GC2, Bellussi LM1, Sarafoleanu C3, Loglisci M1, Manea C3, Iosif C4, Passali FM. (PubMed)
(2) Alternative therapies for chronic rhinosinusitis: A review by Griffin AS1, Cabot P, Wallwork B, Panizza B. (PubMed)
(3) Immune deficiency in chronic rhinosinusitis: screening and treatment by Sergio E. Chiarella and Leslie C. Grammer. (PMC)
Sunday, 8 October 2023
#PhyticAcid Inhibits Proteins Associated with the Onset of #ProstateCancer, Scientists Suggest
Kyle J. Norton
Phytochemicals phytic acid may be the next-generation natural ingredient for the prevention and treatment of prostate cancer, some scientists found.
Cancer is a class of diseases in which a group of cells grow and multiply disordered and uncontrollable way in our body.cells
As cancer continues proliferation, at certain stages it can damage other healthy tissues. Sometimes cancer cells can spread to other organs in the body via lymph or blood.
Prostate cancer is a medical condition caused by the alternation of the cell on the surface of the inner lining of the prostate tissue.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to the statistic, approximately, 1 man in 9 will be diagnosed with prostate cancer during his lifetime and 6 cases in 10 are diagnosed in men aged 65 or older.
Prostate cancer shares common symptoms of an enlarged prostate, including frequent urination particularly at night, weak or interrupted urine flow, and erectile dysfunction.
Symptoms that are not found in enlarged prostate include blood in the urine and blood in the seminal fluid.
If you are experiencing some of the above symptoms, please check with your doctor to rule out the possibility of prostate cancer
The causes of prostate cancer are unknown. The increases with age, especially after age 50. family history. ethnicity, hereditary breast, and ovarian cancer (HBOC) syndrome, and genetic proposition are some risks actors associated with the onset of the disease.
Some researchers suggested that a poor diet is one of the major risk factors found in patients with the disease.
Dr. Amir Bagher, the lead scientist evaluated the dietary patterns and risk of prostate cancer and wrote, "After adjustment for potential confounders, a healthy dietary pattern was associated with decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81; trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037)".
And, "an unhealthy dietary pattern was associated with an increased risk of prostate cancer. However, a healthy dietary pattern was associated with a decreased risk of prostate cancer".
The results strongly suggested that by following a healthy diet pattern, one can substantially reduce the risk of prostate cancer.
Phytic acid (Inositol hexaphosphate) are phytochemical of the organic acid found abundantly in nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds, etc.
In finding a natural ingredient for the treatment of prostate cancer with no side effects, researchers assessed the effects of phytic acid (inositol hexakisphosphate (IP6)) on the activation of phosphoinositide 3-kinase (PI3K)-Akt pathway in promoting survival, proliferation, and angiogenesis in human prostate cancer cells.
In invasive human prostate cancer, PC-3 and C4-2B cells, IP6 treatment of cells suppressed proliferation, and induced apoptosis through protein associated with the apoptotic and cell death programming pathways.
Phytic acid also inhibited cancer cells through proteins associated with cancer cell growth, proliferation, differentiation, motility.
Furthermore, IP6 inhibited transcription and cell migration. through cell cycle arrest at the G1 phase.
Dr. Gu M, the lead scientist, after taking into account co and confounders said, " IP6 suppresses cell survival, proliferation, and angiogenesis but induces death in prostate cancer cells, which might have translational potential in preventing and controlling the growth of advanced and aggressive prostate cancer for which conventional chemotherapy is not effective".
In advanced and androgen-independent human PCa PC-3, Treatment of PC-3 cells with 2 mM IP6 strongly inhibited both growth and proliferation and decreased cell viability; similar effects were also observed in other human PCa DU145 and LNCaP cells.
IP6 also caused a strong apoptotic death of PC-3 cells through proteins associated with the activation of cell death programming and induced apoptosis.
The inhibition of the PC-3 cancer cell line by IP6 also is associated with the inhibition of the protein-involved cells proliferation, and differentiation, similar to that of the above study.
Interestingly, researchers also discovered that IP6 also inhibited the transcription factor activity in promoting cancer cell growth and reproduction, and regeneration
Where a transcription factor (TF) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA.
Taken al\\together, phytochemicals phytic acid may be considered a bioactive compound for the prevention and combined with the primary therapy for the treatment of prostate cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as a potential target by Gu M, Roy S, Raina K, Agarwal C, Agarwal R.(PubMed)
(2) Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells. by Gu M, Raina K, Agarwal C, Agarwal R.(PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, Seyed Mostafa Nachvak, Mansour Rezaei, 3 Mozhgan Moravridzade, Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
Phytochemicals phytic acid may be the next-generation natural ingredient for the prevention and treatment of prostate cancer, some scientists found.
Cancer is a class of diseases in which a group of cells grow and multiply disordered and uncontrollable way in our body.cells
As cancer continues proliferation, at certain stages it can damage other healthy tissues. Sometimes cancer cells can spread to other organs in the body via lymph or blood.
Prostate cancer is a medical condition caused by the alternation of the cell on the surface of the inner lining of the prostate tissue.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to the statistic, approximately, 1 man in 9 will be diagnosed with prostate cancer during his lifetime and 6 cases in 10 are diagnosed in men aged 65 or older.
Prostate cancer shares common symptoms of an enlarged prostate, including frequent urination particularly at night, weak or interrupted urine flow, and erectile dysfunction.
Symptoms that are not found in enlarged prostate include blood in the urine and blood in the seminal fluid.
If you are experiencing some of the above symptoms, please check with your doctor to rule out the possibility of prostate cancer
The causes of prostate cancer are unknown. The increases with age, especially after age 50. family history. ethnicity, hereditary breast, and ovarian cancer (HBOC) syndrome, and genetic proposition are some risks actors associated with the onset of the disease.
Some researchers suggested that a poor diet is one of the major risk factors found in patients with the disease.
Dr. Amir Bagher, the lead scientist evaluated the dietary patterns and risk of prostate cancer and wrote, "After adjustment for potential confounders, a healthy dietary pattern was associated with decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81; trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037)".
And, "an unhealthy dietary pattern was associated with an increased risk of prostate cancer. However, a healthy dietary pattern was associated with a decreased risk of prostate cancer".
The results strongly suggested that by following a healthy diet pattern, one can substantially reduce the risk of prostate cancer.
Phytic acid (Inositol hexaphosphate) are phytochemical of the organic acid found abundantly in nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds, etc.
In finding a natural ingredient for the treatment of prostate cancer with no side effects, researchers assessed the effects of phytic acid (inositol hexakisphosphate (IP6)) on the activation of phosphoinositide 3-kinase (PI3K)-Akt pathway in promoting survival, proliferation, and angiogenesis in human prostate cancer cells.
In invasive human prostate cancer, PC-3 and C4-2B cells, IP6 treatment of cells suppressed proliferation, and induced apoptosis through protein associated with the apoptotic and cell death programming pathways.
Phytic acid also inhibited cancer cells through proteins associated with cancer cell growth, proliferation, differentiation, motility.
Furthermore, IP6 inhibited transcription and cell migration. through cell cycle arrest at the G1 phase.
Dr. Gu M, the lead scientist, after taking into account co and confounders said, " IP6 suppresses cell survival, proliferation, and angiogenesis but induces death in prostate cancer cells, which might have translational potential in preventing and controlling the growth of advanced and aggressive prostate cancer for which conventional chemotherapy is not effective".
In advanced and androgen-independent human PCa PC-3, Treatment of PC-3 cells with 2 mM IP6 strongly inhibited both growth and proliferation and decreased cell viability; similar effects were also observed in other human PCa DU145 and LNCaP cells.
IP6 also caused a strong apoptotic death of PC-3 cells through proteins associated with the activation of cell death programming and induced apoptosis.
The inhibition of the PC-3 cancer cell line by IP6 also is associated with the inhibition of the protein-involved cells proliferation, and differentiation, similar to that of the above study.
Interestingly, researchers also discovered that IP6 also inhibited the transcription factor activity in promoting cancer cell growth and reproduction, and regeneration
Where a transcription factor (TF) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA.
Taken al\\together, phytochemicals phytic acid may be considered a bioactive compound for the prevention and combined with the primary therapy for the treatment of prostate cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as a potential target by Gu M, Roy S, Raina K, Agarwal C, Agarwal R.(PubMed)
(2) Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells. by Gu M, Raina K, Agarwal C, Agarwal R.(PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, Seyed Mostafa Nachvak, Mansour Rezaei, 3 Mozhgan Moravridzade, Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
#Honey Used Alone Or Combined with Conventional Medicines Process a Strong Anti-Influenza Virus Activity, Researchers Show
Kyle J. Norton
Scientists may have found a natural alternative for the treatment of Influenza, according to studies. Influenza, also known as the flu, is an infectious disease caused by an influenza virus.
The most common symptoms include high fever, runny nose, sore throat, muscle pains, headache, coughing, and sneezing. A healthy individual may recover from influenza without medication in a few days with the symptoms that may last for a week.
However, people with a weakened immune system may have a problem to recover themselves without the assistance of medication. In severe cases, influenza can induce complications of pneumonia, ear, and sinus infection, and death.
People with medical conditions such as heart, lung, kidney, liver disease, AIDs, and severe anemia are at a higher risk of the onset of influenza, particularly in the elderly with a weakened immune system.
Children and adolescents who are receiving long-term aspirin therapy are at risk of being infected by the virus.
Furthermore, some researchers suggested that obese individuals also are more likely to be infected by influenza, compared to non-obese individuals.
Dr. J Justin Milner, the lead scientist in examining the obesity and influenza infection severity said, "Obesity also increases susceptibility to bacterial and viral infections [2]. In 2009, the CDC identified obesity as a risk factor for hospitalization and death from pandemic H1N1 influenza virus infection".
And, "An association between obesity and severe influenza outcomes, including seasonal influenza, has since been corroborated in other epidemiological studies".
The finding strongly indicated the risk of influenza in obesity.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
With an aim to find a natural whole food for the treatment of influenza, researchers examined the anti-influenza viral activity of honey from various sources.
Antiviral activities of honey samples were evaluated in MDCK cells. Injection of Manuka honey efficiently inhibited influenza virus replication (IC50 5 3.6 1.2 mg/mL; CC50 5 82.3 2.2 mg/mL; selective index 5 22.9).
Furthermore,. In the presence of 3.13 mg/mL manuka honey, the IC50 of zanamivir or oseltamivir was reduced to nearly 1/1000th of their single use.
The finding clearly suggested that Manuka honey processes a strong anti-influenza activity when used alone or by promoting the function of conventional medicine when used combinational.
Some researchers suggested that manuka also inhibited the symptoms of influenza such as blocked sinuses, sore throat and coughs through its major compound Methylglyoxal (MGO).
Moreover, Manuka honey also inhibited the production of proinflammatory cytokines during the acute phase of influenza, thus providing instant relief fa or a sore throat and cough.
In the immune perspective, Manuka honey also increased the expression of serum immunoglobulin G (IgG) which plays a critical role against the onset of infection by microorganisms.
Dr. Ogi M, the lead scientist after taking into account co and confounders said, "The relative risk for bacterial infection among patients with serum immunoglobulin G (IgG) levels below 600 mg/dL was 6.74 compared with that for patients with serum IgG levels over 600 mg/dL (95% confidence interval, 1.22 to 36.32; P = 0.029)"
And "In patients with serum creatinine levels over 2.0 mg/dL, the relative risk of bacterial infection was 5.31 compared with patients with serum creatinine levels below 2.0 mg/dL (95% confidence interval, 1.08 to 26.09; P = 0.040)".
The finding also suggested that Manuka honey also can modulate immune expression to prevent the infection caused by the influenza virus by increased production of immunoglobulin G.
Taken together, there is no doubt that Manuka honey can be considered a functional remedy for the prevention and treatment of influenza, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Anti-influenza viral effects of honey in vitro: the potent high activity of manuka honey by Watanabe K1, Rahmasari R1, Matsunaga A1, Haruyama T2, Kobayashi N. (EL SEVIER)
(2) Manuka Honey the best Natural Cold and Flu Remedy By Mr. Vitamins
(3) Risk factors for infection and immunoglobulin replacement therapy in adult nephrotic syndrome by Ogi M1, Yokoyama H, Tomosugi N, Hisada Y, Ohta S, Takaeda M, Wada T, Naito T, Ikeda K, Goshima S. (PubMed)
(4) Obesity and influenza infection severity by J Justin Milner & Melinda A Beck. (Future Medicine)
Scientists may have found a natural alternative for the treatment of Influenza, according to studies. Influenza, also known as the flu, is an infectious disease caused by an influenza virus.
The most common symptoms include high fever, runny nose, sore throat, muscle pains, headache, coughing, and sneezing. A healthy individual may recover from influenza without medication in a few days with the symptoms that may last for a week.
However, people with a weakened immune system may have a problem to recover themselves without the assistance of medication. In severe cases, influenza can induce complications of pneumonia, ear, and sinus infection, and death.
People with medical conditions such as heart, lung, kidney, liver disease, AIDs, and severe anemia are at a higher risk of the onset of influenza, particularly in the elderly with a weakened immune system.
Children and adolescents who are receiving long-term aspirin therapy are at risk of being infected by the virus.
Furthermore, some researchers suggested that obese individuals also are more likely to be infected by influenza, compared to non-obese individuals.
Dr. J Justin Milner, the lead scientist in examining the obesity and influenza infection severity said, "Obesity also increases susceptibility to bacterial and viral infections [2]. In 2009, the CDC identified obesity as a risk factor for hospitalization and death from pandemic H1N1 influenza virus infection".
And, "An association between obesity and severe influenza outcomes, including seasonal influenza, has since been corroborated in other epidemiological studies".
The finding strongly indicated the risk of influenza in obesity.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
With an aim to find a natural whole food for the treatment of influenza, researchers examined the anti-influenza viral activity of honey from various sources.
Antiviral activities of honey samples were evaluated in MDCK cells. Injection of Manuka honey efficiently inhibited influenza virus replication (IC50 5 3.6 1.2 mg/mL; CC50 5 82.3 2.2 mg/mL; selective index 5 22.9).
Furthermore,. In the presence of 3.13 mg/mL manuka honey, the IC50 of zanamivir or oseltamivir was reduced to nearly 1/1000th of their single use.
The finding clearly suggested that Manuka honey processes a strong anti-influenza activity when used alone or by promoting the function of conventional medicine when used combinational.
Some researchers suggested that manuka also inhibited the symptoms of influenza such as blocked sinuses, sore throat and coughs through its major compound Methylglyoxal (MGO).
Moreover, Manuka honey also inhibited the production of proinflammatory cytokines during the acute phase of influenza, thus providing instant relief fa or a sore throat and cough.
In the immune perspective, Manuka honey also increased the expression of serum immunoglobulin G (IgG) which plays a critical role against the onset of infection by microorganisms.
Dr. Ogi M, the lead scientist after taking into account co and confounders said, "The relative risk for bacterial infection among patients with serum immunoglobulin G (IgG) levels below 600 mg/dL was 6.74 compared with that for patients with serum IgG levels over 600 mg/dL (95% confidence interval, 1.22 to 36.32; P = 0.029)"
And "In patients with serum creatinine levels over 2.0 mg/dL, the relative risk of bacterial infection was 5.31 compared with patients with serum creatinine levels below 2.0 mg/dL (95% confidence interval, 1.08 to 26.09; P = 0.040)".
The finding also suggested that Manuka honey also can modulate immune expression to prevent the infection caused by the influenza virus by increased production of immunoglobulin G.
Taken together, there is no doubt that Manuka honey can be considered a functional remedy for the prevention and treatment of influenza, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Anti-influenza viral effects of honey in vitro: the potent high activity of manuka honey by Watanabe K1, Rahmasari R1, Matsunaga A1, Haruyama T2, Kobayashi N. (EL SEVIER)
(2) Manuka Honey the best Natural Cold and Flu Remedy By Mr. Vitamins
(3) Risk factors for infection and immunoglobulin replacement therapy in adult nephrotic syndrome by Ogi M1, Yokoyama H, Tomosugi N, Hisada Y, Ohta S, Takaeda M, Wada T, Naito T, Ikeda K, Goshima S. (PubMed)
(4) Obesity and influenza infection severity by J Justin Milner & Melinda A Beck. (Future Medicine)
#Alliin Works Synergistically with Other Antioxidants to Promote Anti-Angiogenesis and Anti Cancer Activity, Researchers Show
Kyle J. Norton
Angiogenesis is the process that promotes the formation of new blood vessels involving many factors including the migration, growth, and differentiation of endothelial cells.
Believe it or not, all active tissues in the body are at a distance less than a hundred micrometers from a blood capillary formed by the process of angiogenesis.
Angiogenesis is important for the cells for the diffusion exchange of nutrients and metabolites through the small blood vessels.
In normal and healthy conditions, stimulating angiogenesis has been found to have a therapeutic effect for the treatment of ischemic heart disease, peripheral arterial disease, and wound healing.
However, in cancers, stimulating angiogenesis in tumor cells has been associated with tumor proliferation and metastasis.
In other words, the angiogenesis process a function of a double sword, on one hand, the process provides an ideal condition for diseases and wound healing. On the other hand, it promotes invasive and overgrowth tumors.
Genentech in the article "Tumor Angiogenesis and the VEGF Pathway" wrote, "Angiogenesis is a necessary part of the process in the progression of cancer from small, localized neoplasms to larger, growing, and potentially metastatic tumors. To grow beyond 1 to 2 mm in diameter, a tumor needs an independent blood supply, which is acquired by the expression of growth factors that recruit new vasculature from existing blood vessels".
"This process continues even as the tumor matures. Thus, the upregulation of angiogenesis is a key step in sustained tumor growth and may also be critical for tumor metastasis".
In other words, by inhibiting the process of blood vessel formation of the tumor, cancer may be curable.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
In the urgency to find a potential ingredient for the treatment of cancer with no side effect, scientists examined the phytochemical alliin, a compound derived from garlic anti-angiogenesis activity.
In the chick chorioallantoic membrane, the injection of alliin exerted a significant effect on the inhibition of fibroblast growth factor-2 (FGF2) associated with the angiogenesis.
In the CAM model, alliin also inhibited the vascular endothelial growth factor (VEGF)-induced angiogenesis.
Combined with antioxidant vitamins C and E significantly (P < 0.001) enhanced the function of alliin inhibitory efficacy on FGF2-induced EC tube formation and angiogenesis, particularly in the colon and fibrosarcoma tumor growth.
More precisely, alliin significantly inhibited both FGF2 and VEGF secretion from human fibrosarcoma cells compared to other types of tumors in a concentration-dependent manner
However, the anti-angiogenesis of alliin was reversed if the NO synthesis inhibitor nitro-L-arginine methyl ester (L-NAME) was injected.
The efficacy of alliin was attributed to the activation of the expression of a protein involved in immune tumor suppression.
In other words, alliin worked synergistically with other antioxidants to promote anti-angiogenesis and anticancer efficacy.
Dr. Mousa AS, the lead scientist wrote, "These data also suggest the implication of cellular NO and p53 as mediators of anti-angiogenesis and anticancer effects of alliin".
Taken together, alliin may be considered a supplement for the inhibition of angiogenesis in the promotion of tumor growth, pending the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53 by Mousa AS1, Mousa SA. (PubMed)
(2) Tumor Angiogenesis and the VEGF Pathway by The Genentech
Angiogenesis is the process that promotes the formation of new blood vessels involving many factors including the migration, growth, and differentiation of endothelial cells.
Believe it or not, all active tissues in the body are at a distance less than a hundred micrometers from a blood capillary formed by the process of angiogenesis.
Angiogenesis is important for the cells for the diffusion exchange of nutrients and metabolites through the small blood vessels.
In normal and healthy conditions, stimulating angiogenesis has been found to have a therapeutic effect for the treatment of ischemic heart disease, peripheral arterial disease, and wound healing.
However, in cancers, stimulating angiogenesis in tumor cells has been associated with tumor proliferation and metastasis.
In other words, the angiogenesis process a function of a double sword, on one hand, the process provides an ideal condition for diseases and wound healing. On the other hand, it promotes invasive and overgrowth tumors.
Genentech in the article "Tumor Angiogenesis and the VEGF Pathway" wrote, "Angiogenesis is a necessary part of the process in the progression of cancer from small, localized neoplasms to larger, growing, and potentially metastatic tumors. To grow beyond 1 to 2 mm in diameter, a tumor needs an independent blood supply, which is acquired by the expression of growth factors that recruit new vasculature from existing blood vessels".
"This process continues even as the tumor matures. Thus, the upregulation of angiogenesis is a key step in sustained tumor growth and may also be critical for tumor metastasis".
In other words, by inhibiting the process of blood vessel formation of the tumor, cancer may be curable.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
In the urgency to find a potential ingredient for the treatment of cancer with no side effect, scientists examined the phytochemical alliin, a compound derived from garlic anti-angiogenesis activity.
In the chick chorioallantoic membrane, the injection of alliin exerted a significant effect on the inhibition of fibroblast growth factor-2 (FGF2) associated with the angiogenesis.
In the CAM model, alliin also inhibited the vascular endothelial growth factor (VEGF)-induced angiogenesis.
Combined with antioxidant vitamins C and E significantly (P < 0.001) enhanced the function of alliin inhibitory efficacy on FGF2-induced EC tube formation and angiogenesis, particularly in the colon and fibrosarcoma tumor growth.
More precisely, alliin significantly inhibited both FGF2 and VEGF secretion from human fibrosarcoma cells compared to other types of tumors in a concentration-dependent manner
However, the anti-angiogenesis of alliin was reversed if the NO synthesis inhibitor nitro-L-arginine methyl ester (L-NAME) was injected.
The efficacy of alliin was attributed to the activation of the expression of a protein involved in immune tumor suppression.
In other words, alliin worked synergistically with other antioxidants to promote anti-angiogenesis and anticancer efficacy.
Dr. Mousa AS, the lead scientist wrote, "These data also suggest the implication of cellular NO and p53 as mediators of anti-angiogenesis and anticancer effects of alliin".
Taken together, alliin may be considered a supplement for the inhibition of angiogenesis in the promotion of tumor growth, pending the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53 by Mousa AS1, Mousa SA. (PubMed)
(2) Tumor Angiogenesis and the VEGF Pathway by The Genentech
3,3'-Diindolylmethane Exhibits Cytotocxicity and Apoptosis Againast #LiverCancer Cells, Researchers Find
Kyle J. Norton
Scientists may have found a bioactive ingredient for the treatment of liver cancer with no side effects, according to studies.
The liver is the largest internal organ in the human body which plays a critical role in maintaining the integrity of cell walls, the production of vitamin D and steroid hormones, and aiding the digestive system in the absorption of nutrients, through the production of cholesterol.
Additionally, the liver also filters out waste from the blood coming from the digestive system before passing it to the other parts of the body.
Liver cancer is a medical condition caused by irregular cell growth in the tissues of the liver.
Most cases of liver cancer start in the cells on the surface of the inner lining of the liver tissues before penetrating into deeper layers of the liver.
At the early stage due to the small size of the tumor and lack of nerve tissues, most patients are asymptomatic.
However, at the advanced stage, cancer cells can travel a distance away from the liver to infect other healthy tissues and organs, leading to secondary metastasis.
Patients at this stage may experience the general symptoms of cancers such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue accompanied by the symptoms of persistent upper abdominal pain, abdominal swelling, jaundice, and chalky stools.
If you have some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility of liver cancer.
Out of many risk factors associated with the onset of liver cancer, some researchers suggested that people who carry hepatitis viral may have a substantially higher risk of the disease.
Dr. Marc Ringehan, the lead researcher said, "Hepatitis B and C viruses are a global health problem causing acute and chronic infections that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the leading cause of HCC worldwide and are associated with significant mortality, accounting for more than 1.3 million deaths per year".
And, "The majority of viral-associated HCC cases develop in subjects with liver cirrhosis; however, hepatitis B virus infection can promote HCC development without prior end-stage liver disease".
Scientists in seeking potential and bioactive compounds for the treatment of liver cancer examined 3'3-Diindolylmethane (DIM, the major product of the acid-catalyzed oligomerization of indole-3-carbinol anti-liver cancer properties.
In two HCC cell lines SMMC-7721 and MHCC-97H, injection of DIM inhibited the proliferation, migration, and invasion of cancer cells.
In nude mice, DIM significantly decreased the volumes of SMMC-7721 orthotopic liver tumors and suppressed lung metastasis.
Furthermore, DIM decreased the level of phospho-FAK (Tyr397) which is found elevated in both vitro and in vivo.
The DIM anti-cancer cells' efficacy on proliferation, migration, and invasion is probably due to the inhibition of the expression of matrixes (MMP2-9) associated with the promotion of cancer cell growth and invasion.
Dr. Li WX, the lead scientist wrote, "These results demonstrated that DIM blocks HCC cell metastasis by suppressing tumor cell migration and invasion".
Moreover, in order to reveal more information about DIM anti-liver cancer activity, researchers investigated whether diindolylmethane affects HA59T cells.
At concentrations of 10-75 μM, diindolylmethane killed cells in a concentration-dependent manner, particularly, in diindolylmethane (25-50 μM) induced apoptosis in a concentration-dependent manner.
The cytotoxic effect of diindolylmethane against the tested liver cancer cell line was not reversed by chelating cytosolic Ca(2+)
Where Calcium (Ca2+) ions are important for cellular signaling. Its flow plays an essential role in regulating several secondary messenger systems in neural adaptation for the visual, auditory, and olfactory systems.
The results suggested that DIM inhibited the onset and progression of liver cancer through a number of mechanisms, including proteins involved in anti-cell proliferation and migration, and the promotion of apoptosis.
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of liver cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3'3-Diindolylmethane inhibits migration, invasion, and metastasis of hepatocellular carcinoma by suppressing FAK signaling by Li WX1, Chen LP2, Sun MY1, Li JT1, Liu HZ1, Zhu W. (PubMed)
(2) Effect of diindolylmethane on Ca(2+) movement and viability in HA59T human hepatoma cells by Cheng JS1, Shu SS, Kuo CC, Chou CT, Tsai WL, Fang YC, Kuo LN, Yeh JH, Chen WC, Chien JM, Lu T, Pan CC, Cheng HH, Chai KL, Jan CR. (PubMed)
(3) Viral hepatitis and liver cancer by Marc Ringehan,1,2,3 Jane A. McKeating,4,5 and Ulrike Protzer. (PMC)
Scientists may have found a bioactive ingredient for the treatment of liver cancer with no side effects, according to studies.
The liver is the largest internal organ in the human body which plays a critical role in maintaining the integrity of cell walls, the production of vitamin D and steroid hormones, and aiding the digestive system in the absorption of nutrients, through the production of cholesterol.
Additionally, the liver also filters out waste from the blood coming from the digestive system before passing it to the other parts of the body.
Liver cancer is a medical condition caused by irregular cell growth in the tissues of the liver.
Most cases of liver cancer start in the cells on the surface of the inner lining of the liver tissues before penetrating into deeper layers of the liver.
At the early stage due to the small size of the tumor and lack of nerve tissues, most patients are asymptomatic.
However, at the advanced stage, cancer cells can travel a distance away from the liver to infect other healthy tissues and organs, leading to secondary metastasis.
Patients at this stage may experience the general symptoms of cancers such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue accompanied by the symptoms of persistent upper abdominal pain, abdominal swelling, jaundice, and chalky stools.
If you have some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility of liver cancer.
Out of many risk factors associated with the onset of liver cancer, some researchers suggested that people who carry hepatitis viral may have a substantially higher risk of the disease.
Dr. Marc Ringehan, the lead researcher said, "Hepatitis B and C viruses are a global health problem causing acute and chronic infections that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the leading cause of HCC worldwide and are associated with significant mortality, accounting for more than 1.3 million deaths per year".
And, "The majority of viral-associated HCC cases develop in subjects with liver cirrhosis; however, hepatitis B virus infection can promote HCC development without prior end-stage liver disease".
Scientists in seeking potential and bioactive compounds for the treatment of liver cancer examined 3'3-Diindolylmethane (DIM, the major product of the acid-catalyzed oligomerization of indole-3-carbinol anti-liver cancer properties.
In two HCC cell lines SMMC-7721 and MHCC-97H, injection of DIM inhibited the proliferation, migration, and invasion of cancer cells.
In nude mice, DIM significantly decreased the volumes of SMMC-7721 orthotopic liver tumors and suppressed lung metastasis.
Furthermore, DIM decreased the level of phospho-FAK (Tyr397) which is found elevated in both vitro and in vivo.
The DIM anti-cancer cells' efficacy on proliferation, migration, and invasion is probably due to the inhibition of the expression of matrixes (MMP2-9) associated with the promotion of cancer cell growth and invasion.
Dr. Li WX, the lead scientist wrote, "These results demonstrated that DIM blocks HCC cell metastasis by suppressing tumor cell migration and invasion".
Moreover, in order to reveal more information about DIM anti-liver cancer activity, researchers investigated whether diindolylmethane affects HA59T cells.
At concentrations of 10-75 μM, diindolylmethane killed cells in a concentration-dependent manner, particularly, in diindolylmethane (25-50 μM) induced apoptosis in a concentration-dependent manner.
The cytotoxic effect of diindolylmethane against the tested liver cancer cell line was not reversed by chelating cytosolic Ca(2+)
Where Calcium (Ca2+) ions are important for cellular signaling. Its flow plays an essential role in regulating several secondary messenger systems in neural adaptation for the visual, auditory, and olfactory systems.
The results suggested that DIM inhibited the onset and progression of liver cancer through a number of mechanisms, including proteins involved in anti-cell proliferation and migration, and the promotion of apoptosis.
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of liver cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3'3-Diindolylmethane inhibits migration, invasion, and metastasis of hepatocellular carcinoma by suppressing FAK signaling by Li WX1, Chen LP2, Sun MY1, Li JT1, Liu HZ1, Zhu W. (PubMed)
(2) Effect of diindolylmethane on Ca(2+) movement and viability in HA59T human hepatoma cells by Cheng JS1, Shu SS, Kuo CC, Chou CT, Tsai WL, Fang YC, Kuo LN, Yeh JH, Chen WC, Chien JM, Lu T, Pan CC, Cheng HH, Chai KL, Jan CR. (PubMed)
(3) Viral hepatitis and liver cancer by Marc Ringehan,1,2,3 Jane A. McKeating,4,5 and Ulrike Protzer. (PMC)
#Herbal #Ginger Inhibits the Onset of #Gastric/Stomach Ulcers Induced by Aspirin, According to Studies
Kyle J. Norton
Gastric ulcers or stomach ulcers are conditions characterized by painful sores in the stomach lining. Unlike the gastric ulcers, peptic ulcers are sores found in the stomach and small intestines.
The exact causes of gastric ulcers are not clearly identified. However, according to epidemiological studies, a bacterial infection caused by H. pylori infection has been found in the range of 30 to 50% of people with stomach ulcers.
Gastric ulcers caused by H. pylori infection are more likely to develop in patients over 40 in the US
Other risk factors associated with gastric ulcers include long-term use of certain medications, such as NSAID which has been found to cause more than 50% of peptic ulcers and stress.
Treatment of gastric ulcers is depended totally on the underlying causes, including antacids for the reduced acid in the stomach, and antibiotics for the elimination of Helicobacter pylori.
Unfortunately, people with gastric ulcers infected by Helicobacter pylori treated with antibiotics have a higher risk of recurrence. In severe cases, surgery may be necessary.
Untreated or uncovered stomach ulcers may induce some complications, including stomach bleeding penetration, and cancer.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a potential ingredient for the treatment of gastric ulcers with no side effects, researchers examined the possible mechanism of the protective effect of ginger on aspirin-induced gastric ulcers.
The study included 40 adult male albino rats randomized and divided into four groups (10 animals per each group) and orally received the following once daily for 5 days:
Group I: 3 ml of 1% carboxymethyl cellulose;
Group II: ginger powder (200 mg/kg body weight) suspended in 3 mL of 1% carboxymethylcellulose;
Group III: aspirin (400 mg/kg body weight) suspended in 3 ml of 1% carboxymethylcellulose in water.
Group IV: ginger and 30 minutes later, received aspirin suspended in 1% carboxymethylcellulose, in similar doses as received in groups II and III.
Before the treatment of ginger, aspirin-induced a significant increase in the macroscopic ulcer score, and gastric damage was observed by the shed and disrupted epithelium, mucosal hemorrhage, submucosal edema and leukocyte infiltration, loss of the mucus of the mucosal surface.
Furthermore, in the protein's perspective, Aspirin significantly increased the expression of apoptosis regulator Bax, inducible nitric oxide synthase (iNOS) associated with the production of proinflammatory cytokines and heat shock protein 70 (HSP70) involved stress response.
Injection of ginger protected the gastric integrity by restoring all damage caused by aspirin in the induction of gastric ulcer.
Dr. Salah Khalil M, said, "Ginger ameliorated the histological changes by reducing Bax and iNOS and increasing HSP70 expressions".
In other words, the overexpression of proteins associated with the onset of gastric ulcer also was significantly reduced by ginger administration.
Taken together, ginger may be considered a functional alternative for the treatment of gastric ulcers, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The postulated mechanism of the protective effect of ginger on the aspirin induced gastric ulcer: Histological and immunohistochemical studies by Salah Khalil M. (PubMed)
(2) Synbiotic (probiotic and ginger extract) loaded floating beads: a novel therapeutic option in an experimental paradigm of gastric ulcer by Singh PK1, Kaur IP. (PubMed)
Gastric ulcers or stomach ulcers are conditions characterized by painful sores in the stomach lining. Unlike the gastric ulcers, peptic ulcers are sores found in the stomach and small intestines.
The exact causes of gastric ulcers are not clearly identified. However, according to epidemiological studies, a bacterial infection caused by H. pylori infection has been found in the range of 30 to 50% of people with stomach ulcers.
Gastric ulcers caused by H. pylori infection are more likely to develop in patients over 40 in the US
Other risk factors associated with gastric ulcers include long-term use of certain medications, such as NSAID which has been found to cause more than 50% of peptic ulcers and stress.
Treatment of gastric ulcers is depended totally on the underlying causes, including antacids for the reduced acid in the stomach, and antibiotics for the elimination of Helicobacter pylori.
Unfortunately, people with gastric ulcers infected by Helicobacter pylori treated with antibiotics have a higher risk of recurrence. In severe cases, surgery may be necessary.
Untreated or uncovered stomach ulcers may induce some complications, including stomach bleeding penetration, and cancer.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a potential ingredient for the treatment of gastric ulcers with no side effects, researchers examined the possible mechanism of the protective effect of ginger on aspirin-induced gastric ulcers.
The study included 40 adult male albino rats randomized and divided into four groups (10 animals per each group) and orally received the following once daily for 5 days:
Group I: 3 ml of 1% carboxymethyl cellulose;
Group II: ginger powder (200 mg/kg body weight) suspended in 3 mL of 1% carboxymethylcellulose;
Group III: aspirin (400 mg/kg body weight) suspended in 3 ml of 1% carboxymethylcellulose in water.
Group IV: ginger and 30 minutes later, received aspirin suspended in 1% carboxymethylcellulose, in similar doses as received in groups II and III.
Before the treatment of ginger, aspirin-induced a significant increase in the macroscopic ulcer score, and gastric damage was observed by the shed and disrupted epithelium, mucosal hemorrhage, submucosal edema and leukocyte infiltration, loss of the mucus of the mucosal surface.
Furthermore, in the protein's perspective, Aspirin significantly increased the expression of apoptosis regulator Bax, inducible nitric oxide synthase (iNOS) associated with the production of proinflammatory cytokines and heat shock protein 70 (HSP70) involved stress response.
Injection of ginger protected the gastric integrity by restoring all damage caused by aspirin in the induction of gastric ulcer.
Dr. Salah Khalil M, said, "Ginger ameliorated the histological changes by reducing Bax and iNOS and increasing HSP70 expressions".
In other words, the overexpression of proteins associated with the onset of gastric ulcer also was significantly reduced by ginger administration.
Taken together, ginger may be considered a functional alternative for the treatment of gastric ulcers, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The postulated mechanism of the protective effect of ginger on the aspirin induced gastric ulcer: Histological and immunohistochemical studies by Salah Khalil M. (PubMed)
(2) Synbiotic (probiotic and ginger extract) loaded floating beads: a novel therapeutic option in an experimental paradigm of gastric ulcer by Singh PK1, Kaur IP. (PubMed)
Gelam and Acacia Honey Process Anti-Obesity Property with Inducing Liver Toxicity, Researchers Find
Kyle J. Norton
In seeking natural therapy with no side effects, scientists may have found a bee-based product for the treatment of obesity, according to studies.
Compared to an ideal weight, that reduces the risk of cardiovascular disease, body weight greater than 20 percent is considered obese.
Obesity is a medical condition caused by excess body fat that has accumulated over time, while overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered overweight, while a BMI of over 30 is an indication of obesity.
Epidemiological studies in the investigation of the complications of obesity found that cardiovascular problems such as high blood pressure, heart disease, accelerated atherosclerosis, stroke... and chronic lower back pain are the most common disease complications associated with obesity.
According to data from the National Health and Nutrition Examination Survey (NHANES), 2013–2014, more than 1 in 3 and 13 adults in the US were considered to have obesity and extreme obesity, respectively.
Although there are many risk factors involved the onset of the disease, some researchers suggest an unhealthy lifestyle is one of the major causes of obesity in the Western world.
Dr. Robert F. Kushner, in the examination of the unhealthy lifestyle risk of obesity of the 53‐item lifestyle pattern questionnaire posted on a commercial weight loss program Web site collected from 2004 through 2008, wrote, "Unhealthy lifestyle patterns in diet, exercise, and coping were highly prevalent among this population".
The results findings clearly suggested a strong correlation between diet, exercise, and obesity.
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In the urgency to find a natural remedy for the treatment of widespread obesity in the Western world, researchers evaluated the potential of honey consumption in controlling obesity.
The study compared the two local Malaysian honey types: Gelam and Acacia honey activities in reducing excess weight gain and other parameters related to obesity.
Male Sprague-Dawley rats selected for the study were induced obese by a high-fat diet (HFD) prior to introduction with/without honey or orlistat for four weeks.
Rats fed with Gelam honey showed significant reductions in excess weight gain and adiposity index compared to HFD rats.
Furthermore, parameters related to obesity such as levels of plasma glucose, triglycerides, and cholesterol, plasma leptin and resistin, liver enzymes, renal function, and relative organ weight in Gelam and Acacia honey-treated groups were reduced significantly, compared to obese rats.
Compared to the treatment of orlistat, Gelam, and Acacia honey showed similar results without inducing hepatotoxicity effects.
Hepatotoxicity is a known side effect of orlistat.
Where Orlistat is a drug used for the treatment of obesity, sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.
Dr. Samat S, the lead scientists wrote in the final report, "consumption of honey can be used to control obesity by regulating lipid metabolism and appears to be more effective than orlistat".
Taken altogether, hiney, particularly Gelam and Acacia honey may be considered anti-obesity functional remedies with no side effects, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Four-Week Consumption of Malaysian Honey Reduces Excess Weight Gain and Improves Obesity-Related Parameters in High Fat Diet Induced Obese Rats by Samat S1, Kanyan Enchang F1, Nor Hussein F2, Wan Ismail WI. (PubMed)
In seeking natural therapy with no side effects, scientists may have found a bee-based product for the treatment of obesity, according to studies.
Compared to an ideal weight, that reduces the risk of cardiovascular disease, body weight greater than 20 percent is considered obese.
Obesity is a medical condition caused by excess body fat that has accumulated over time, while overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered overweight, while a BMI of over 30 is an indication of obesity.
Epidemiological studies in the investigation of the complications of obesity found that cardiovascular problems such as high blood pressure, heart disease, accelerated atherosclerosis, stroke... and chronic lower back pain are the most common disease complications associated with obesity.
According to data from the National Health and Nutrition Examination Survey (NHANES), 2013–2014, more than 1 in 3 and 13 adults in the US were considered to have obesity and extreme obesity, respectively.
Although there are many risk factors involved the onset of the disease, some researchers suggest an unhealthy lifestyle is one of the major causes of obesity in the Western world.
Dr. Robert F. Kushner, in the examination of the unhealthy lifestyle risk of obesity of the 53‐item lifestyle pattern questionnaire posted on a commercial weight loss program Web site collected from 2004 through 2008, wrote, "Unhealthy lifestyle patterns in diet, exercise, and coping were highly prevalent among this population".
The results findings clearly suggested a strong correlation between diet, exercise, and obesity.
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In the urgency to find a natural remedy for the treatment of widespread obesity in the Western world, researchers evaluated the potential of honey consumption in controlling obesity.
The study compared the two local Malaysian honey types: Gelam and Acacia honey activities in reducing excess weight gain and other parameters related to obesity.
Male Sprague-Dawley rats selected for the study were induced obese by a high-fat diet (HFD) prior to introduction with/without honey or orlistat for four weeks.
Rats fed with Gelam honey showed significant reductions in excess weight gain and adiposity index compared to HFD rats.
Furthermore, parameters related to obesity such as levels of plasma glucose, triglycerides, and cholesterol, plasma leptin and resistin, liver enzymes, renal function, and relative organ weight in Gelam and Acacia honey-treated groups were reduced significantly, compared to obese rats.
Compared to the treatment of orlistat, Gelam, and Acacia honey showed similar results without inducing hepatotoxicity effects.
Hepatotoxicity is a known side effect of orlistat.
Where Orlistat is a drug used for the treatment of obesity, sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.
Dr. Samat S, the lead scientists wrote in the final report, "consumption of honey can be used to control obesity by regulating lipid metabolism and appears to be more effective than orlistat".
Taken altogether, hiney, particularly Gelam and Acacia honey may be considered anti-obesity functional remedies with no side effects, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Four-Week Consumption of Malaysian Honey Reduces Excess Weight Gain and Improves Obesity-Related Parameters in High Fat Diet Induced Obese Rats by Samat S1, Kanyan Enchang F1, Nor Hussein F2, Wan Ismail WI. (PubMed)
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