Kyle J. Norton
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.
As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.
* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell
Diabetic cardiomyopathy is a complication found in patients with diabetes associated with reducing the heart function in circulating blood through the body, leading to heart failure and increased accumulation of fluid in the lungs.
Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.
* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.
* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.
The most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of heart diseases, researchers examined the effect of sulforaphane, an active compound and an Nrf2 activator found in broccoli on diabetic cardiomyopathy (DCM), male db/db and age-matched wild-type (WT) mice.
According to the experimental results from the analysis of broccoli sprout extract (BSE) by gavage every other day for 3 months, with four groups: vehicle (0.1 ml/10 g), BSE-low dose (estimated SFN availability at 0.5 mg/kg), BSE-high dose (estimated SFN availability at 1.0 mg/kg), and SFN (0.5 mg/kg),
* BSE, like SFN, showed a significant up-regulation of the Nrf2 transcriptional activity involved in the enhancing antioxidant enzymes observed by the increased Nrf2 nuclear accumulation and gene expression.
* The increased levels of antioxidant enzymes exerted a strong effect on the prevention of cardiac oxidative damage and inflammation.
* Additionally, the BSE at high dose provided a similar effect as did SFN.
Based on the results, researchers wrote, " BSE at high dose prevents DCM in a manner congruent with SFN treatment. Therefore, it suggests that BSE could potentially be used as a natural and safe treatment against DCM via Nrf2 activation".
Taken together, broccoli sprouts processed abundantly SFN may be considered supplements for the prevention of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice by Xu Z1,2, Wang S1,2, Ji H1, Zhang Z1, Chen J2, Tan Y2,3, Wintergerst K3,4, Zheng Y1, Sun J1, Cai L. (PubMed)
Sunday, 8 October 2023
#ManukaHoney in the Treatment of Severe Atopic Contact #Dermatitis Eczematous Reaction, Researchers Reveal
Kyle J. Norton
In seeking natural therapy with no side effects, scientists may have found an herbal remedy for the prevention and treatment of atopic dermatitis, according to studies.
Atopic dermatitis or eczema is an inflammatory condition associated with red and itchy skin.
Most cases of atopic dermatitis are found in children. However, adults may also get it too. Skin irritation is found more often in children compared to adults.
The causes of atopic dermatitis are unknown. Some researchers suggested that certain risk factors such as genetic preposition and abnormal function of the immune system and environment conditions may be involved in the development of the disease.
Epidemiological studies suggested that most patients with chronic atopic dermatitis also have asthma and hay fever, particularly in allergies.
Some researchers suggested that atopic dermatitis is more common in people who live in the air pollution city.
Dr. Ahn K in the study of the role of air pollutants in atopic dermatitis, wrote, " Both indoor and outdoor air pollution, which are of increasing concern with urbanization, are well-known environmental risk factors for asthma, whereas there is relatively little evidence in AD".
And, " epidemiologic and experimental data on the role of air pollution in patients with AD. Recent evidence suggests that a variety of air pollutants, such as environmental tobacco smoke, volatile organic compounds, formaldehyde, toluene, nitrogen dioxide, and particulate matter, act as risk factors for the development or aggravation of AD. These air pollutants probably induce oxidative stress in the skin, leading to skin barrier dysfunction or immune dysregulation".
The results clearly suggested the risk of atopic dermatitis increases with air pollutants.
Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers in the course to find a natural ingredient for the treatment of dermatitis examined the Manuka honey anti-skin conditions and dermal injuries.
Injection of Manuka honey showed a significant potency in the treatment of a severe atopic contact dermatitis eczematous reaction with no side effects.
Furthermore, adult volunteers with bilateral atopic dermatitis (AD) were asked to apply MH on one site overnight for seven consecutive days and leave the contralateral site untreated as possible.
There are no significant changes in the skin staphylococci observed after day 7, irrespective of honey treatment.
However, MH treatment showed significant inhibition of proinflammatory cytokines in a dose-dependent manner.
The application of MK also inhibited mast cell degranulation against the onset of atopic dermatitis (AD).
Dr. Alangari AA, the lead scientist said in the final report, "MH is potentially effective in the treatment of AD lesions based on both clinical and cellular studies through different mechanisms".
Taken together, Manuka honey may be considered a functional remedy for the prevention and treatment of atopic dermatitis (AD) with no side effects, pending the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Manuka Honey: A Case Study of Severe Atopic Eczematous Dermatitis Reaction to Henna Tattoo by Harrison J. (PubMed)
(2) Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies by Alangari AA1, Morris K2, Lwaleed BA3, Lau L4, Jones K2, Cooper R2, Jenkins R. (PubMed)
(3) The role of air pollutants in atopic dermatitis by Ahn K. (PubMed)
In seeking natural therapy with no side effects, scientists may have found an herbal remedy for the prevention and treatment of atopic dermatitis, according to studies.
Atopic dermatitis or eczema is an inflammatory condition associated with red and itchy skin.
Most cases of atopic dermatitis are found in children. However, adults may also get it too. Skin irritation is found more often in children compared to adults.
The causes of atopic dermatitis are unknown. Some researchers suggested that certain risk factors such as genetic preposition and abnormal function of the immune system and environment conditions may be involved in the development of the disease.
Epidemiological studies suggested that most patients with chronic atopic dermatitis also have asthma and hay fever, particularly in allergies.
Some researchers suggested that atopic dermatitis is more common in people who live in the air pollution city.
Dr. Ahn K in the study of the role of air pollutants in atopic dermatitis, wrote, " Both indoor and outdoor air pollution, which are of increasing concern with urbanization, are well-known environmental risk factors for asthma, whereas there is relatively little evidence in AD".
And, " epidemiologic and experimental data on the role of air pollution in patients with AD. Recent evidence suggests that a variety of air pollutants, such as environmental tobacco smoke, volatile organic compounds, formaldehyde, toluene, nitrogen dioxide, and particulate matter, act as risk factors for the development or aggravation of AD. These air pollutants probably induce oxidative stress in the skin, leading to skin barrier dysfunction or immune dysregulation".
The results clearly suggested the risk of atopic dermatitis increases with air pollutants.
Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers in the course to find a natural ingredient for the treatment of dermatitis examined the Manuka honey anti-skin conditions and dermal injuries.
Injection of Manuka honey showed a significant potency in the treatment of a severe atopic contact dermatitis eczematous reaction with no side effects.
Furthermore, adult volunteers with bilateral atopic dermatitis (AD) were asked to apply MH on one site overnight for seven consecutive days and leave the contralateral site untreated as possible.
There are no significant changes in the skin staphylococci observed after day 7, irrespective of honey treatment.
However, MH treatment showed significant inhibition of proinflammatory cytokines in a dose-dependent manner.
The application of MK also inhibited mast cell degranulation against the onset of atopic dermatitis (AD).
Dr. Alangari AA, the lead scientist said in the final report, "MH is potentially effective in the treatment of AD lesions based on both clinical and cellular studies through different mechanisms".
Taken together, Manuka honey may be considered a functional remedy for the prevention and treatment of atopic dermatitis (AD) with no side effects, pending the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Manuka Honey: A Case Study of Severe Atopic Eczematous Dermatitis Reaction to Henna Tattoo by Harrison J. (PubMed)
(2) Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies by Alangari AA1, Morris K2, Lwaleed BA3, Lau L4, Jones K2, Cooper R2, Jenkins R. (PubMed)
(3) The role of air pollutants in atopic dermatitis by Ahn K. (PubMed)
#Polysaccharides Found in #Broccoli Exert Anti-Metastatic Activities by stimulatiing of NK and other Immune Cells, According to Studies
Kyle J. Norton
Cancer is a class of diseases associated with irregular cell growth in the tissue of a specific organ.
Most cases of invasive cancer can spread to other organs in the body via lymph or blood.
According to the statistics provided by the Cancer Institute, between n 2011–2015, the number of new cases of cancer was 439.2 per 100,000 men and women per year (based on 2011–2015 cases).
The number of cancer deaths (cancer mortality) is 163.5 per 100,000 men and women per year.
In cancer cells, due to the alternation of DNA, can grow indefinitely.
Cancer cell metastasis is the process which cancer cells break away from the primary site and travel through the blood or fluid circulation and form new tumors (metastatic tumors) in other parts of the body, similar to those of primary cancer.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Through the expression of the lines of defense, depending on the stage of pathogenic invasion, the innate immune response protects the body via a different set of interactions.
In the acute phase of infection, the macrophages in the immune system stimulate the production of inflammatory cytokines at the site of the damage. The inflammatory cytokines not only play a critical role in stopping the stimuli from entering the body but also speed up wound healing through growth factors.
The innate immune system also can destroy damaged cells such as cancer cells through the T cell activation of B cells which in turn stimulates the production of a protein associated with the production of antibody p53.
Some researchers suggested immune system also can kill cancer cells by reacting to activating cytokines (IFN-α/β, IL-12, IL-15, IL-18, IL-21) produced by tumor cells or by other immune cells stimulated by tumor cells.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
In finding natural food for the prevention and treatment of cancer proliferation, researchers examined the anti-metastatic activities of polysaccharides in broccoli, including BCE-I mainly consisted of galactose and arabinose, whereas BCE-II mainly consisted of galacturonic acid and rhamnose, and BCE-III mainly consisted of rhamnose and galactose.
According to the results of the analysis,
* BCE-I showed the greatest enhancement of the pro-inflammatory proteins such as tumor necrosis factor-α, interleukin (IL)-12, and IL-6 secretion by stimulating murine peritoneal macrophages in the immune response.
* Furthermore, intravenous (i.v.) administration of BCE-I enhanced the lethal activity on YAC-1 tumor cells significantly and dose-dependently in ex vivo by exhibiting the natural killer (NK) cells.
* On lung metastasis of Colon26-M3.1 carcinoma cells, prophylactic i.v. and oral administration of BCE-I significantly and dose-dependently inhibited lung metastatic activity.
In other words, the inhibitory activity of BCE-1 on lung metastasis depends on the NK cell function in GM1 activity.
Based on the results, researchers wrote, " BCE-I has potent antitumor metastatic activity, and that its anti-metastatic activity has relevance to the stimulation of NK and other immune cells".
Taken altogether, broccoli sprouts processed abundantly SFN may be considered supplements for inhibiting cancer cell metastasis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation by Kwak BS1, Hwang D2,3, Lee SJ1, Choi HJ4, Park HY5, Shin KS. (PubMed)
Cancer is a class of diseases associated with irregular cell growth in the tissue of a specific organ.
Most cases of invasive cancer can spread to other organs in the body via lymph or blood.
According to the statistics provided by the Cancer Institute, between n 2011–2015, the number of new cases of cancer was 439.2 per 100,000 men and women per year (based on 2011–2015 cases).
The number of cancer deaths (cancer mortality) is 163.5 per 100,000 men and women per year.
In cancer cells, due to the alternation of DNA, can grow indefinitely.
Cancer cell metastasis is the process which cancer cells break away from the primary site and travel through the blood or fluid circulation and form new tumors (metastatic tumors) in other parts of the body, similar to those of primary cancer.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Through the expression of the lines of defense, depending on the stage of pathogenic invasion, the innate immune response protects the body via a different set of interactions.
In the acute phase of infection, the macrophages in the immune system stimulate the production of inflammatory cytokines at the site of the damage. The inflammatory cytokines not only play a critical role in stopping the stimuli from entering the body but also speed up wound healing through growth factors.
The innate immune system also can destroy damaged cells such as cancer cells through the T cell activation of B cells which in turn stimulates the production of a protein associated with the production of antibody p53.
Some researchers suggested immune system also can kill cancer cells by reacting to activating cytokines (IFN-α/β, IL-12, IL-15, IL-18, IL-21) produced by tumor cells or by other immune cells stimulated by tumor cells.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
In finding natural food for the prevention and treatment of cancer proliferation, researchers examined the anti-metastatic activities of polysaccharides in broccoli, including BCE-I mainly consisted of galactose and arabinose, whereas BCE-II mainly consisted of galacturonic acid and rhamnose, and BCE-III mainly consisted of rhamnose and galactose.
According to the results of the analysis,
* BCE-I showed the greatest enhancement of the pro-inflammatory proteins such as tumor necrosis factor-α, interleukin (IL)-12, and IL-6 secretion by stimulating murine peritoneal macrophages in the immune response.
* Furthermore, intravenous (i.v.) administration of BCE-I enhanced the lethal activity on YAC-1 tumor cells significantly and dose-dependently in ex vivo by exhibiting the natural killer (NK) cells.
* On lung metastasis of Colon26-M3.1 carcinoma cells, prophylactic i.v. and oral administration of BCE-I significantly and dose-dependently inhibited lung metastatic activity.
In other words, the inhibitory activity of BCE-1 on lung metastasis depends on the NK cell function in GM1 activity.
Based on the results, researchers wrote, " BCE-I has potent antitumor metastatic activity, and that its anti-metastatic activity has relevance to the stimulation of NK and other immune cells".
Taken altogether, broccoli sprouts processed abundantly SFN may be considered supplements for inhibiting cancer cell metastasis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation by Kwak BS1, Hwang D2,3, Lee SJ1, Choi HJ4, Park HY5, Shin KS. (PubMed)
#CruciferousVegetables Modulatie Key miRNA Agaisnt the Risk of #ColorectalCancer, Researchers Say
Kyle J. Norton
The colon-rectum formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of the cell's DNA.
Colorectal cancer is a relatively very common and slowly progressing cancer.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
In general, the 5-year survival rate for people with colorectal cancer is 65%. However, the 5-year survival rate of localized colorectal cancer is about 90%.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, aging, family and personal history, and genetic preposition are some of the prevalent risks of the disease.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
In finding a potential compound for the treatment of cancer, researchers examined the effects of cruciferous vegetables and their active compounds on colorectal cancer.
According to the dietary information, cruciferous vegetables modulated microRNA (miRNAs) expression in the cancer cells and exerted chemo-preventive effects against colorectal cancers.
Cruciferous vegetables also interacted with the cancer-related gene and relevant signaling pathways to induce apoptosis and cytotoxicity.
Furthermore, by inhibiting the miRNA expression associated with cancer biomarkers, cruciferous vegetables improved the diagnostic and prognostic biomarkers and were utilized in cancer therapeutics.
Based on the findings, researchers wrote, "It is very possible that natural agents (not limited to those in cruciferous vegetables) enhance cancer therapeutic efficacy and elicit chemopreventive effects through modulating key miRNAs".
Taken together, cruciferous vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous vegetables and colorectal cancer prevention through microRNA regulation: A review by Pan JH1, Abernathy B2, Kim YJ3, Lee JH3, Kim JH3, Shin EC4, Kim JK. (PubMed)
The colon-rectum formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of the cell's DNA.
Colorectal cancer is a relatively very common and slowly progressing cancer.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
In general, the 5-year survival rate for people with colorectal cancer is 65%. However, the 5-year survival rate of localized colorectal cancer is about 90%.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, aging, family and personal history, and genetic preposition are some of the prevalent risks of the disease.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
In finding a potential compound for the treatment of cancer, researchers examined the effects of cruciferous vegetables and their active compounds on colorectal cancer.
According to the dietary information, cruciferous vegetables modulated microRNA (miRNAs) expression in the cancer cells and exerted chemo-preventive effects against colorectal cancers.
Cruciferous vegetables also interacted with the cancer-related gene and relevant signaling pathways to induce apoptosis and cytotoxicity.
Furthermore, by inhibiting the miRNA expression associated with cancer biomarkers, cruciferous vegetables improved the diagnostic and prognostic biomarkers and were utilized in cancer therapeutics.
Based on the findings, researchers wrote, "It is very possible that natural agents (not limited to those in cruciferous vegetables) enhance cancer therapeutic efficacy and elicit chemopreventive effects through modulating key miRNAs".
Taken together, cruciferous vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous vegetables and colorectal cancer prevention through microRNA regulation: A review by Pan JH1, Abernathy B2, Kim YJ3, Lee JH3, Kim JH3, Shin EC4, Kim JK. (PubMed)
The Effects #Coffee and Coffee #Caffeine Intake on the Risk of Ulcerative Colitis, Reserachers Find
Kyle J. Norton
Epidemiological studies do not agree that the intake of coffee and caffeine caffeine regularly may have a profound effect in attenuating the risk of ulcerative colitis.
Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
Ulcerative colitis is an inflammatory bowel disease characterized by long-lasting inflammation and ulcers (sores) in the digestive tract.
In the reviewed study of a total of 442 patients, 73% regularly consume coffee. 96% of patients attributing a positive and 91% of patients attributing no impact of coffee intake on IBD regularly drink coffee and surprisingly even 49% of those patients that assign a negative impact on disease symptoms, researchers at the University Hospital Zurich found that most patient with IBD showed a coffee drinking habit and addressed that coffee has helped to modify symptoms of the disease.
Other in the total of 81 UC patients recruited at all stages of the disease process, after completion of a 7 d diet diary, Caffeine, and decaffeinated coffee showed a clinical significance in reduced risk of UC and may be considered a functional food included in the potential therapeutic diet.
Dr. Magee EA, the lead author said, " ......decaffeinated coffee was associated with a better clinical state than the caffeine-containing version".
Contrastively, the investigation of a population-based, case-control study of the risk of ulcerative colitis associated with coffee and alcohol use among the 304,000 members of a prepaid health plan, coffee expressed no association with either amount of coffee consumed daily, or cumulative coffee consumption before disease onset and altered the risk of developing ulcerative colitis.
Taken together, the findings showed an inclusive result of the efficacy of coffee and coffee caffeine consumption in reducing the risk of ulcerative colitis. Therefore more cohost with large sample size studies is necessary before coffee can be confirmed as a functional food for use in reduced onset and treatment of ulcerative colitis.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Patients' perceptions on the impact of coffee consumption in inflammatory bowel disease: friend or foe?--a patient survey by Barthel C1,2, Wiegand S3,4, Scharl S5, Scharl M6,7, Frei P8, Vavricka SR9, Fried M10, Sulz MC11,12, Wiegand N13,14, Rogler G15,16, Biedermann L17.(PubMed)
(2) Associations between diet and disease activity in ulcerative colitis patients using a novel method of data analysis by Magee EA1, Edmond LM, Tasker SM, Kong SC, Curno R, Cummings JH.(PubMed)
(3) Coffee and alcohol use and the risk of ulcerative colitis by Boyko EJ1, Perera DR, Koepsell TD, Keane EM, Inui TS.(PubMed)
Epidemiological studies do not agree that the intake of coffee and caffeine caffeine regularly may have a profound effect in attenuating the risk of ulcerative colitis.
Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
Ulcerative colitis is an inflammatory bowel disease characterized by long-lasting inflammation and ulcers (sores) in the digestive tract.
In the reviewed study of a total of 442 patients, 73% regularly consume coffee. 96% of patients attributing a positive and 91% of patients attributing no impact of coffee intake on IBD regularly drink coffee and surprisingly even 49% of those patients that assign a negative impact on disease symptoms, researchers at the University Hospital Zurich found that most patient with IBD showed a coffee drinking habit and addressed that coffee has helped to modify symptoms of the disease.
Other in the total of 81 UC patients recruited at all stages of the disease process, after completion of a 7 d diet diary, Caffeine, and decaffeinated coffee showed a clinical significance in reduced risk of UC and may be considered a functional food included in the potential therapeutic diet.
Dr. Magee EA, the lead author said, " ......decaffeinated coffee was associated with a better clinical state than the caffeine-containing version".
Contrastively, the investigation of a population-based, case-control study of the risk of ulcerative colitis associated with coffee and alcohol use among the 304,000 members of a prepaid health plan, coffee expressed no association with either amount of coffee consumed daily, or cumulative coffee consumption before disease onset and altered the risk of developing ulcerative colitis.
Taken together, the findings showed an inclusive result of the efficacy of coffee and coffee caffeine consumption in reducing the risk of ulcerative colitis. Therefore more cohost with large sample size studies is necessary before coffee can be confirmed as a functional food for use in reduced onset and treatment of ulcerative colitis.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Patients' perceptions on the impact of coffee consumption in inflammatory bowel disease: friend or foe?--a patient survey by Barthel C1,2, Wiegand S3,4, Scharl S5, Scharl M6,7, Frei P8, Vavricka SR9, Fried M10, Sulz MC11,12, Wiegand N13,14, Rogler G15,16, Biedermann L17.(PubMed)
(2) Associations between diet and disease activity in ulcerative colitis patients using a novel method of data analysis by Magee EA1, Edmond LM, Tasker SM, Kong SC, Curno R, Cummings JH.(PubMed)
(3) Coffee and alcohol use and the risk of ulcerative colitis by Boyko EJ1, Perera DR, Koepsell TD, Keane EM, Inui TS.(PubMed)
#Dietary Patterns are Associated with an Increased or a Reduced Risk of #MetabolicSyndrome, According to Studies
Kyle J. Norton
A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverages in a diet as well as the frequency of the foods that are habitually consumed.
The most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, and high salt, and sugar foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes is increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
In finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 years of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A Western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The Western pattern has a strong and negative impact on increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels comapred to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverages in a diet as well as the frequency of the foods that are habitually consumed.
The most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, and high salt, and sugar foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes is increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
In finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 years of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A Western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The Western pattern has a strong and negative impact on increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels comapred to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
#Honey Relieves Hangover by Significantly Decreasing the Blood Ethanol Concentration., Scientists Reveal
Kyle J. Norton
According to Dr. Zhou, a scientist in the field of TCM, honey has cooling, hydrating, and revitalizing properties and has been used in traditional Chinese medicine as a purifying stimulant and a tonic against dizziness and hangover-upset stomachs.
A hangover is the unpleasant physiological and psychological effect caused by the (over) consumption of alcohol, according to studies.
The most common symptoms of a hangover include a headache, drowsiness, concentration problems, dizziness, fatigue, and gastrointestinal discomforts.
The exact causes of the hangover are unknown. The most common factor associated with a hangover is the accumulation of acetaldehyde, a highly toxic substance.
The conversion of acetaldehyde is a chemical process as a result of the enzyme alcohol dehydrogenase (ADH) which metabolizes the alcohol intake to acetaldehyde.
Depending on the individual variations in alcohol metabolism, some people may experience worse hangover symptoms than others.
Hangover symptoms are affected by alcohol tolerance which is measured by the bodily responses to the functional effects of ethanol in alcoholic beverages.
CYP2E1, one of the genes has been linked with alcohol tolerance. However, people with high alcohol tolerance are also more likely to develop alcoholism.
Dr. Claire Heit,, the lead scientist in the evaluation of the role of CYP2E1 in alcohol metabolism wrote, "Acetaldehyde (the direct metabolite of ethanol oxidation) contributes to many aspects of the behavioral effects of ethanol. Given acetaldehyde cannot pass through the blood-brain barrier, its concentration in the CNS is primarily determined by local production from ethanol".
And, "Catalase and cytochrome P450 2E1(CYP2E1) represent the major enzymes in the CNS that catalyze ethanol oxidation. CYP2E1 is expressed abundantly within the microsomes of certain brain cells and is localized to particular brain regions".
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Scientists on finding a natural and potential compound for hangover relief examined the traditional medicine use of honey for preventing drunkenness and relieving hangover symptoms.
Intoxicated male mice selected for the study were assigned randomly either to low or high doses of lychee flower honey (2.19 or 4.39 g/kg body weight, respectively) that were single orally administrated 30 min before the ethanol intoxication of mice, followed by recording the locomotor activity by autonomic activity instrument and observing the climbing ability after alcohol or 2.19 g/kg honey that was single orally administrated 5 min after the ethanol intoxication of mice, followed by determining the ethanol concentration in mice blood.
Both doses of honey increased the autonomic activity of alcoholized mice.
Furthermore, intoxicated mice treated with 2.19 g/kg honey showed a significant decrease significantly of blood ethanol concentration.
Additional differentiation suggested that The anti-intoxication activity of honey is attributed to the effect of the fructose contained in the honey.
Interestingly, honey inhibited hangover symptoms without affecting the levels of oxidative stress and antioxidant enzymes produced by the host.
The results showed that honey processed a direct anti-hangover activity in a dose-time-dependent manner.
Taken altogether, honey may be considered a functional remedy to relieve hangover symptoms caused by alcoholic intoxication, pending to the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Honey reduces blood alcohol concentration but not affects the level of serum MDA and GSH-Px activity in intoxicated male mice models by Shi P1,2, Chen B3, Chen C1, Xu J3, Shen Z1, Miao X4,5, Yao H. (PubMed)
(2) The Role of CYP2E1 in Alcohol Metabolism and Sensitivity in the Central Nervous System
Claire Heit, Hongbin Dong,b Ying Chen, David C. Thompson,c Richard A. Deitrich,d and Vasilis Vasiliou. (PMC)
(3) Curing hangovers the Chinese way by Timeout
According to Dr. Zhou, a scientist in the field of TCM, honey has cooling, hydrating, and revitalizing properties and has been used in traditional Chinese medicine as a purifying stimulant and a tonic against dizziness and hangover-upset stomachs.
A hangover is the unpleasant physiological and psychological effect caused by the (over) consumption of alcohol, according to studies.
The most common symptoms of a hangover include a headache, drowsiness, concentration problems, dizziness, fatigue, and gastrointestinal discomforts.
The exact causes of the hangover are unknown. The most common factor associated with a hangover is the accumulation of acetaldehyde, a highly toxic substance.
The conversion of acetaldehyde is a chemical process as a result of the enzyme alcohol dehydrogenase (ADH) which metabolizes the alcohol intake to acetaldehyde.
Depending on the individual variations in alcohol metabolism, some people may experience worse hangover symptoms than others.
Hangover symptoms are affected by alcohol tolerance which is measured by the bodily responses to the functional effects of ethanol in alcoholic beverages.
CYP2E1, one of the genes has been linked with alcohol tolerance. However, people with high alcohol tolerance are also more likely to develop alcoholism.
Dr. Claire Heit,, the lead scientist in the evaluation of the role of CYP2E1 in alcohol metabolism wrote, "Acetaldehyde (the direct metabolite of ethanol oxidation) contributes to many aspects of the behavioral effects of ethanol. Given acetaldehyde cannot pass through the blood-brain barrier, its concentration in the CNS is primarily determined by local production from ethanol".
And, "Catalase and cytochrome P450 2E1(CYP2E1) represent the major enzymes in the CNS that catalyze ethanol oxidation. CYP2E1 is expressed abundantly within the microsomes of certain brain cells and is localized to particular brain regions".
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Scientists on finding a natural and potential compound for hangover relief examined the traditional medicine use of honey for preventing drunkenness and relieving hangover symptoms.
Intoxicated male mice selected for the study were assigned randomly either to low or high doses of lychee flower honey (2.19 or 4.39 g/kg body weight, respectively) that were single orally administrated 30 min before the ethanol intoxication of mice, followed by recording the locomotor activity by autonomic activity instrument and observing the climbing ability after alcohol or 2.19 g/kg honey that was single orally administrated 5 min after the ethanol intoxication of mice, followed by determining the ethanol concentration in mice blood.
Both doses of honey increased the autonomic activity of alcoholized mice.
Furthermore, intoxicated mice treated with 2.19 g/kg honey showed a significant decrease significantly of blood ethanol concentration.
Additional differentiation suggested that The anti-intoxication activity of honey is attributed to the effect of the fructose contained in the honey.
Interestingly, honey inhibited hangover symptoms without affecting the levels of oxidative stress and antioxidant enzymes produced by the host.
The results showed that honey processed a direct anti-hangover activity in a dose-time-dependent manner.
Taken altogether, honey may be considered a functional remedy to relieve hangover symptoms caused by alcoholic intoxication, pending to the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Honey reduces blood alcohol concentration but not affects the level of serum MDA and GSH-Px activity in intoxicated male mice models by Shi P1,2, Chen B3, Chen C1, Xu J3, Shen Z1, Miao X4,5, Yao H. (PubMed)
(2) The Role of CYP2E1 in Alcohol Metabolism and Sensitivity in the Central Nervous System
Claire Heit, Hongbin Dong,b Ying Chen, David C. Thompson,c Richard A. Deitrich,d and Vasilis Vasiliou. (PMC)
(3) Curing hangovers the Chinese way by Timeout
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