Kyle J. Norton
Scientists may have found a kitchen spice that processes the potential to induce cancer cell death by cytotoxicity, according to studies.
Cytotoxicity is a process that stimulates the ability of certain chemicals or mediator cells to destroy living cells.
In herbal medicine, injection of plant extracts in some cases also induce cytotoxic effects to kill cancer cells without causing harm to nearby healthy cells through the protection of increased production of antioxidant enzymes.
In other words, the use of herbal medicine for the treatment of cancer can induce no side effects.
In cancer, the cytotoxic activity is carried out by the overexpression reactive oxygen activity, leading to cancer cell apoptosis through a number of mechanisms, including cell death programming and cell cycle arrest proteins.
In healthy cells, the ROS cytotoxic activity can also cause significant damage to the proteins, lipids, and DNA, leading to the onset of chronic diseases, including cancer.
Some researchers suggested that activating the expression gene associated with tumor suppression to prevent the damage of healthy cells during the injection of chemo drugs may provide a necessary step for the prevention of chemo side effects in cancer patients.
Dr. Chit Fang Cheok, in the differentiation of protecting normal cells from the cytotoxicity of chemotherapy, wrote, "The occurrence of intolerable side effects in patients undergoing chemotherapy is still a major clinical hurdle. Finding tumor-specific therapy and exploiting the differences between normal cells and tumor cells has led to strategies targeting oncogenic mutations or the deficiency of tumor suppressor pathways in cancers".
And, "The concept requires the use of two drugs, the first to arrest the normal cells and the second, to kill only cycling (tumor) cells".
More interestingly, "several recent studies demonstrate that p53 activation protects normal cells from the toxicity of drugs acting in the S-phase or M-phase, including Ara-C,2 taxol,3 Aurora kinase inhibitors4, and Polo-like kinase inhibitors".
These results strongly suggested the model provided by herbal medicine may some days be used by conventional medicine for the treatment of cancer without causing severe side effects.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers to find a natural ingredient for the treatment of cancer examined ginger's cytotoxic activity on cancer cells.
In vivo, researchers compared the anticancer effect of ginger in a total of 80 OV and nitrosamine (OV/ DMN)-induced CCA hamsters fed with the ginger extract at doses of 1000, 3000, and 5000 mg/kg body weight daily or every alternate day for 30 days vs control groups consisting of 10 hamsters for each group fed with 5-fluorouracil (positive control) or distilled water (untreated control).
Injection of crude ethanolic extracts of ginger at a dose of 10.95, 53.15, and 27.86 μg/ml with Median IC50 (concentration that inhibits cell growth by 50%) values exerted strong cytotoxicity and antioxidant activities.
The crude ethanolic extracts of ginger demonstrated a 7-9 fold in the function of genes associated with the transportation of the chemo drugs observed by the DNA fragments on the cancer cell line.
The extract also induced acute and subacute toxicity at the maximum dose of 5,000 mg/kg body weight.
Furthermore, the injection displayed a strong effect on the survival time and survival rate of the CCA-bearing hamsters compared to the control group (median of 54 vs 17 weeks.
Dr. Plengsuriyakarn T, the lead scientist said, "Results from these in vitro and in vivo studies thus indicate promising anticancer activity of the crude ethanolic extract of ginger against CCA with the absence of any significant toxicity".
Moreover, in the examined ginger anti-cancer activity, researchers investigated the cytotoxic and antitumor activity of ginger essential oil (GEO).
GEO showed potent in vitro cytotoxic activity against DLA and EAC cell lines. The IC50 values for the DLA cell line and EAC cell line were 18 μg/ml. were found to be 11 μg/ml and 18 μg/ml, respectively.
However, on L929 cell lines and to Vero cells, The IC50 of GEO was found to be 41 μg/ml and ˃100 ug/ml, respectively, significantly higher compared to the DLA cell line and EAC cell line.
Additionally, treatment with GEO (500 mg/kg and 1000 mg/kg body weight) significantly reduced the volume of solid tumor development by 54.4% and 62.4% respectively and the lifespan was increased up to 50% in 1000 mg/kg b. wt GEO treated ascites tumor-induced animals.
The findings once again, reconfirm the cytotoxic and antitumor effects of ginger.
Taken together, ginger, the kitchen, and pungent spice may be considered a functional food for the prevention and combined with primary therapy for the treatment of cancer with no or little side effects, pending the validity of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Cytotoxicity, toxicity, and anticancer activity of Zingiber officinale Roscoe against cholangiocarcinoma by Plengsuriyakarn T1, Viyanant V, Eursitthichai V, Tesana S, Chaijaroenkul W, Itharat A, Na-Bangchang K. (PubMed)
(2) Antitumor and cytotoxic activity of ginger essential oil (Zingiber officinale roscoe) by Jeena Kottarapat, Vijayasteltar B Liju, R. Kuttan. (Research Gate)
(3) Protecting normal cells from the cytotoxicity of chemotherapy by Chit Fang Cheok. (PMC)
Friday, 6 October 2023
#GreenTea Shows a Signoificant and Positive Effect on #MetabolicSyndrome, Reserachers Suggest
Kyle J. Norton
A recent study conducted by renowned institutes suggested that regular drinking of green tea may reduce the risk of prevalence of metabolic syndrome.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Metabolic syndrome is a biochemical and physiological factor associated with the risk of cardiovascular disease and type 2 diabetes.
In a cross-sectional population-based survey including 8,821 adults (51.4% female) conducted in Krakow, Poland., both coffee and tea drinkers showed a negative association with MetS (OR 0.75, 95% CI 0.66, 0.86 and OR 0.79, 95% CI 0.67, 0.92, respectively).
The study also found that high tea consumers had lower BMI, and waist circumference, but moderated decreased diastolic blood pressure, as well as negatively correlated central obesity and fasting plasma glucose in women, but not in men, compared to low drinkers,
Other, in the study of dietary polyphenols, a major compound found in green tea including 8821 adults (51.4 % female), using food frequency questionnaires and matching food consumption data with the Phenol-Explorer database. conducted in Kraków, Poland, dietary polyphenol intake in the highest quartile was associated inversely to the development of MetS (OR 0.80; 95 % CI 0.64, 0.98 and OR 0.70; 95 % CI 0.56, 0.86 for both men and women, respectively).
g
Dietary polyphenols in high quality showed a negative association of WC, blood pressure, high lipoprotein cholesterol, and triglycerides in women, and fasting plasma glucose in both genders.
Dr. Grosso G, the lead author said, "(Depending on types of polyphenols) phenolic acids and stilbenes were significantly associated with MetS; lignans and stilbenes with WC; phenolic acids with blood pressure and triglycerides; and flavonoids with fasting plasma glucose" and " Among specific subclasses of polyphenols, hydroxycinnamic acids, flavonols, and dihydrochalcones had the most relevant role."
In support of the role of used of polyphenols in the treatment of Metabolic syndrome, a total of 2725 participants free of hypertension at baseline tested for blood pressure or taking hypertensive medication within the last 2 weeks at 2-4-year follow-up visit was conducted by the Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, researchers showed that diet of highest quartile of total polyphenol intake was associated with 31% decreased risk of hypertension compared with the lowest intake (OR 0.69, 95% CI 0.48, 0.98) in women with no significant association in men.
The study also stated that the most influential phytochemicals in reduced risk and treatment of metabolic syndrome ingredients are phenolic acids, and hydroxycinnamic acids as they showed independently associated with lower odds of hypertension (OR 0.66, 95% CI 0.47, 0.93) in comparison to others.
Taken together, green tea with major chemical compounds of polyphenol may be used as a functional food in the prevention and treatment of metabolic syndrome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3. (PubMed)
(2) Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Stefler D4, Bobak M4, Pająk A3. (PubMed)
(3) Dietary polyphenol intake and risk of hypertension in the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Kozela M3, Stefler D4, Bobak M4, Pajak A3.(PubMed)
A recent study conducted by renowned institutes suggested that regular drinking of green tea may reduce the risk of prevalence of metabolic syndrome.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Metabolic syndrome is a biochemical and physiological factor associated with the risk of cardiovascular disease and type 2 diabetes.
In a cross-sectional population-based survey including 8,821 adults (51.4% female) conducted in Krakow, Poland., both coffee and tea drinkers showed a negative association with MetS (OR 0.75, 95% CI 0.66, 0.86 and OR 0.79, 95% CI 0.67, 0.92, respectively).
The study also found that high tea consumers had lower BMI, and waist circumference, but moderated decreased diastolic blood pressure, as well as negatively correlated central obesity and fasting plasma glucose in women, but not in men, compared to low drinkers,
Other, in the study of dietary polyphenols, a major compound found in green tea including 8821 adults (51.4 % female), using food frequency questionnaires and matching food consumption data with the Phenol-Explorer database. conducted in Kraków, Poland, dietary polyphenol intake in the highest quartile was associated inversely to the development of MetS (OR 0.80; 95 % CI 0.64, 0.98 and OR 0.70; 95 % CI 0.56, 0.86 for both men and women, respectively).
g
Dietary polyphenols in high quality showed a negative association of WC, blood pressure, high lipoprotein cholesterol, and triglycerides in women, and fasting plasma glucose in both genders.
Dr. Grosso G, the lead author said, "(Depending on types of polyphenols) phenolic acids and stilbenes were significantly associated with MetS; lignans and stilbenes with WC; phenolic acids with blood pressure and triglycerides; and flavonoids with fasting plasma glucose" and " Among specific subclasses of polyphenols, hydroxycinnamic acids, flavonols, and dihydrochalcones had the most relevant role."
In support of the role of used of polyphenols in the treatment of Metabolic syndrome, a total of 2725 participants free of hypertension at baseline tested for blood pressure or taking hypertensive medication within the last 2 weeks at 2-4-year follow-up visit was conducted by the Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, researchers showed that diet of highest quartile of total polyphenol intake was associated with 31% decreased risk of hypertension compared with the lowest intake (OR 0.69, 95% CI 0.48, 0.98) in women with no significant association in men.
The study also stated that the most influential phytochemicals in reduced risk and treatment of metabolic syndrome ingredients are phenolic acids, and hydroxycinnamic acids as they showed independently associated with lower odds of hypertension (OR 0.66, 95% CI 0.47, 0.93) in comparison to others.
Taken together, green tea with major chemical compounds of polyphenol may be used as a functional food in the prevention and treatment of metabolic syndrome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3. (PubMed)
(2) Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Stefler D4, Bobak M4, Pająk A3. (PubMed)
(3) Dietary polyphenol intake and risk of hypertension in the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Kozela M3, Stefler D4, Bobak M4, Pajak A3.(PubMed)
#Ginger Inhibits Muscle Pain Caused by Eccentric Exercise, Researchers Reveal
Kyle J. Norton
Scientists may have found a natural ingredient for the treatment of muscle pain with no side effects, according to a study.
Muscle pain is the condition of pain that originates from the muscle. Muscle pain may be caused by injury or overexertion, infections of soft tissues, or inflammatory conditions.
Systemic muscle pain is the pain throughout the body, often induced by an infection, an illness, or a side effect of long-term intake of certain medications, such as cholesterol medications.
There are many risk factors associated with muscle pain, including
1. Physical activity (PA) that requires the intensity, duration, and repetitiveness of muscular activity.
2. Occupations often involve static load, repetitive movements, and high peak forces, occurring for a prolonged duration are also some risk factors that causally relate to muscle pain development.
3. Overtraining in physical exercise.
Most muscle pains can be treated with over-the-counter painkillers. If you are currently taking them for the treatment of muscle pain, please make sure you know all the side effects for preventive measures.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of muscle pain quickly examined the effects of 11 days of raw (study 1) and heat-treated (study 2) ginger supplementation on muscle pain.
Study 1 and 2 were identical double-blind, placebo-controlled, randomized experiments with 34 and 40 volunteers, respectively
Also, participants consumed 2 grams of either raw (study 1) or heated (study 2) ginger or placebo for 11 consecutive days and participants performed 18 eccentric actions of the elbow flexors to induce pain and inflammation.
According to the assays, ginger showed a significant pain reduction in 24 hours after eccentric exercise compared to placebo.
There was no significant difference between both types of ginger and placebo on other measures.
Daily supplementation with ginger reduced muscle pain caused by eccentric exercise, and this effect was not enhanced by heat-treating ginger.
Dr. and colleagues wrote, "Daily consumption of raw and heat-treated ginger resulted in moderate-to-large reductions in muscle pain following exercise-induced muscle injury".
In order to reveal additional information about ginger in treating muscle pain, researchers evaluated the acute effects of ginger on muscle pain, inflammation, and dysfunction induced by eccentric exercise.
The double-blind, cross-over design, included 27 participants who performed 24 eccentric actions of the non-dominant elbow flexors and ingested a 2 g dose of ginger or placebo 24 h and 48 h after exercise.
Before ginger treatment, eccentric exercise caused moderate arm pain (39 ± 20 mm; mean ± SD) dysfunction (14% decrease in ROM), and an increase in volume (1.8%).
Ginger consumption demonstrated no effect on muscle pain, dysfunction, or metabolic rate compared with the placebo before 24 hours.
However, after 24 hours, arm pain was reduced (13%, -5.9 ± 8.8 mm) the following day, 48 h after exercise.
Based on the finding, researchers said, "a single 2 g dose of ginger does not attenuate eccentric exercise-induced muscle pain, inflammation or dysfunction 45 min after ingestion. However, ginger may attenuate the day-to-day progression of muscle pain".
Taken together, ginger may be considered a functional alternative for the treatment of muscle pain after 24 hours, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise by Black CD1, Herring MP, Hurley DJ, O'Connor PJ. (PubMed)
(2) Acute effects of dietary ginger on muscle pain induced by eccentric exercise by Black CD1, O'Connor PJ. (PubMed)
(3) Physical Activity as Cause and Cure of Muscular Pain: Evidence of Underlying Mechanisms by Karen Søgaard and Gisela Sjøgaard. (PMC)
Scientists may have found a natural ingredient for the treatment of muscle pain with no side effects, according to a study.
Muscle pain is the condition of pain that originates from the muscle. Muscle pain may be caused by injury or overexertion, infections of soft tissues, or inflammatory conditions.
Systemic muscle pain is the pain throughout the body, often induced by an infection, an illness, or a side effect of long-term intake of certain medications, such as cholesterol medications.
There are many risk factors associated with muscle pain, including
1. Physical activity (PA) that requires the intensity, duration, and repetitiveness of muscular activity.
2. Occupations often involve static load, repetitive movements, and high peak forces, occurring for a prolonged duration are also some risk factors that causally relate to muscle pain development.
3. Overtraining in physical exercise.
Most muscle pains can be treated with over-the-counter painkillers. If you are currently taking them for the treatment of muscle pain, please make sure you know all the side effects for preventive measures.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of muscle pain quickly examined the effects of 11 days of raw (study 1) and heat-treated (study 2) ginger supplementation on muscle pain.
Study 1 and 2 were identical double-blind, placebo-controlled, randomized experiments with 34 and 40 volunteers, respectively
Also, participants consumed 2 grams of either raw (study 1) or heated (study 2) ginger or placebo for 11 consecutive days and participants performed 18 eccentric actions of the elbow flexors to induce pain and inflammation.
According to the assays, ginger showed a significant pain reduction in 24 hours after eccentric exercise compared to placebo.
There was no significant difference between both types of ginger and placebo on other measures.
Daily supplementation with ginger reduced muscle pain caused by eccentric exercise, and this effect was not enhanced by heat-treating ginger.
Dr. and colleagues wrote, "Daily consumption of raw and heat-treated ginger resulted in moderate-to-large reductions in muscle pain following exercise-induced muscle injury".
In order to reveal additional information about ginger in treating muscle pain, researchers evaluated the acute effects of ginger on muscle pain, inflammation, and dysfunction induced by eccentric exercise.
The double-blind, cross-over design, included 27 participants who performed 24 eccentric actions of the non-dominant elbow flexors and ingested a 2 g dose of ginger or placebo 24 h and 48 h after exercise.
Before ginger treatment, eccentric exercise caused moderate arm pain (39 ± 20 mm; mean ± SD) dysfunction (14% decrease in ROM), and an increase in volume (1.8%).
Ginger consumption demonstrated no effect on muscle pain, dysfunction, or metabolic rate compared with the placebo before 24 hours.
However, after 24 hours, arm pain was reduced (13%, -5.9 ± 8.8 mm) the following day, 48 h after exercise.
Based on the finding, researchers said, "a single 2 g dose of ginger does not attenuate eccentric exercise-induced muscle pain, inflammation or dysfunction 45 min after ingestion. However, ginger may attenuate the day-to-day progression of muscle pain".
Taken together, ginger may be considered a functional alternative for the treatment of muscle pain after 24 hours, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise by Black CD1, Herring MP, Hurley DJ, O'Connor PJ. (PubMed)
(2) Acute effects of dietary ginger on muscle pain induced by eccentric exercise by Black CD1, O'Connor PJ. (PubMed)
(3) Physical Activity as Cause and Cure of Muscular Pain: Evidence of Underlying Mechanisms by Karen Søgaard and Gisela Sjøgaard. (PMC)
#Herbal Ashwagandha Inhibits Cardio-Toxicity Induced by Doxorubicin, Researchers Suggest
Kyle J. Norton
Cardiotoxicity is a condition caused by toxin accumulated in the heart that leads to damage to the heart muscle.
Cardiotoxicity reduces the heart's pumping blood capability, leading to a decrease in oxygen-rich blood to nourish the body tissues and organs.
The most common symptoms of cardiotoxicity, are tiredness fatigue, chronic cough, water retention, and shortness of breath.
If you have experienced some of the aforementioned symptoms that can be healed within a week or 2, please check with your doctor to rule out the possibility.
The most common causes of cardiotoxicity are associated with patients receiving chemotherapy and the intake of certain medications. However, infection, excessive alcohol consumption, medical conditions such as diabetes and thyroid disease, high blood pressure, and thiamine, and Vitamin B deficiency have also been found to induce cardiotoxicity.
Cardiomyopathy is a severe case of cardiotoxicity.
Cardiomyopathy in most occurs in patients under chemotherapy. However, a group of diseases or disorders can also lead to damaged heart muscle. Injury to the heart muscle may induce cardiomyopathy, including viruses - such as human immunodeficiency virus (HIV), infection, long-standing high blood pressure, chronic or long-term alcohol use, and diabetes.
Conventionally, treatment of cardiotoxicity depending on the cause of the disease may include
* Beta-blockers, for the improvement of the blood flow and reduction of palpitations, arrhythmias, and high blood pressure.
*ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow.
* Diuretics, by getting rid of excess fluids that reduce heart function in blood pumping
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers It is considered anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of cardiovascular diseases, researchers examined the protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.
According to the results of the experiment, doxorubicin (10 mg/kg) -)-induced cardiac toxicity in male Wistar rats showed an increase of necrosis and apoptosis in heart tissues.
Furthermore, the elevation of malondialdehyde and protein carbonyl levels and catalase activity associated with the expression of oxidative stress also were found in the doxorubicin (10 mg/kg) rats.
The doxorubicin (10 mg/kg) rats also exhibited depletion of total antioxidant capacity and of superoxide dismutase level in cardiac tissues, accompanied by increases of myeloperoxidase activity, total calcium content, and the expression of Bcl-2 protein in heart tissues.
Most importantly, all parameters induced by the injection of doxorubicin alterations were effectively attenuated by the administration of the purified standardized extract (1.5% withanolides; manufactured by Idea Sphere Inc., American Fork, UT, USA) of Withania somnifera (300 mg/kg).
Based on the evidence, researchers said, "Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug".
Taken together, Ashwagandha may be considered a supplement for the prevention and treatment of cardiotoxicity induced by medications, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats by Hamza A1, Amin A, Daoud S. (PubMed)
Cardiotoxicity is a condition caused by toxin accumulated in the heart that leads to damage to the heart muscle.
Cardiotoxicity reduces the heart's pumping blood capability, leading to a decrease in oxygen-rich blood to nourish the body tissues and organs.
The most common symptoms of cardiotoxicity, are tiredness fatigue, chronic cough, water retention, and shortness of breath.
If you have experienced some of the aforementioned symptoms that can be healed within a week or 2, please check with your doctor to rule out the possibility.
The most common causes of cardiotoxicity are associated with patients receiving chemotherapy and the intake of certain medications. However, infection, excessive alcohol consumption, medical conditions such as diabetes and thyroid disease, high blood pressure, and thiamine, and Vitamin B deficiency have also been found to induce cardiotoxicity.
Cardiomyopathy is a severe case of cardiotoxicity.
Cardiomyopathy in most occurs in patients under chemotherapy. However, a group of diseases or disorders can also lead to damaged heart muscle. Injury to the heart muscle may induce cardiomyopathy, including viruses - such as human immunodeficiency virus (HIV), infection, long-standing high blood pressure, chronic or long-term alcohol use, and diabetes.
Conventionally, treatment of cardiotoxicity depending on the cause of the disease may include
* Beta-blockers, for the improvement of the blood flow and reduction of palpitations, arrhythmias, and high blood pressure.
*ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow.
* Diuretics, by getting rid of excess fluids that reduce heart function in blood pumping
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers It is considered anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of cardiovascular diseases, researchers examined the protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.
According to the results of the experiment, doxorubicin (10 mg/kg) -)-induced cardiac toxicity in male Wistar rats showed an increase of necrosis and apoptosis in heart tissues.
Furthermore, the elevation of malondialdehyde and protein carbonyl levels and catalase activity associated with the expression of oxidative stress also were found in the doxorubicin (10 mg/kg) rats.
The doxorubicin (10 mg/kg) rats also exhibited depletion of total antioxidant capacity and of superoxide dismutase level in cardiac tissues, accompanied by increases of myeloperoxidase activity, total calcium content, and the expression of Bcl-2 protein in heart tissues.
Most importantly, all parameters induced by the injection of doxorubicin alterations were effectively attenuated by the administration of the purified standardized extract (1.5% withanolides; manufactured by Idea Sphere Inc., American Fork, UT, USA) of Withania somnifera (300 mg/kg).
Based on the evidence, researchers said, "Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug".
Taken together, Ashwagandha may be considered a supplement for the prevention and treatment of cardiotoxicity induced by medications, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats by Hamza A1, Amin A, Daoud S. (PubMed)
#Bromelain Processes Anti #ChronicRhinosinusitis Activity, According to Studies
Kyle J. Norton
Rhinosinusitis (RS) is a condition associated with the inflammation of the sinuses and nasal cavity.
Sinusitis is an inflammation of the paranasal sinuses that causes a headache as a result of exposure to a cold or flu virus, or an allergic reaction to pollen, mold, dust, or smoke.
Sinusitis affects 37 million people each year.
Other symptoms of RS include nasal congestion or obstruction, facial or dental pain, purulent rhinorrhea, postnasal drainage, headache, and cough.
Some patients may also experience symptoms of fever, fatigue, hyposmia, ear fullness or pressure, voice changes, epiphora, fever, psychological effects, and fatigue.
If you have some of the above symptoms that last more than 12 weeks, you may have chronic rhinosinusitis,
If you experience some of the aforementioned symptoms without a cold or flu, you may have rhinosinusitis. Conventionally, most cases of bacterial rhinosinusitis (BRS) are treated by antibiotics.
In viral rhinosinusitis (VRS), medication focuses on reducing symptoms and improving quality of life.
Out of many risk factors involved in the onset of the condition, some researchers suggested that people with an immune deficiency may be vulnerable to rhinosinusitis developing.
Dr. Sergio E. Chiarella, the lead scientist wrote, "CRS is a common disease; in those patients with frequent exacerbations or who are refractory to treatment, an immunodeficiency evaluation should be considered. Treatment includes vaccination, antibiotic therapy, immunoglobulin replacement, and surgery".
More precisely, people who are using immune suppressants or weakened and immature immune systems are at an increased risk of rhinosinusitis.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for the treatment of an inflammatory condition associated with the sinuses and nasal cavity, researchers examined the bromelain effects on patients with chronic rhinosinusitis (CRS).
40 patients including 20 patients were given bromelain 500 mg tablet twice daily for 30 days, and 20 controls enrolled in the study.
According to the observation in the turbinate and ethmoid mucosas and in the serum of both groups, bromelain showed significant anti-inflammatory activity in paranasal sinus pathologies.
In other words, the efficacy of bromelain anti-chronic rhinosinusitis was attributed to its function in distribution evenly in the sinuses and nasal cavity.
Taken altogether, bromelain may be considered a supplement for the prevention and treatment of chronic rhinosinusitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis by Passali D1, Passali GC2, Bellussi LM1, Sarafoleanu C3, Loglisci M1, Manea C3, Iosif C4, Passali FM. (PubMed)
(2) Alternative therapies for chronic rhinosinusitis: A review by Griffin AS1, Cabot P, Wallwork B, Panizza B. (PubMed)
(3) Immune deficiency in chronic rhinosinusitis: screening and treatment by Sergio E. Chiarella and Leslie C. Grammer. (PMC)
#Herbal #Angelica Inhibits Oxidativestress In the Induction of Inflammation, Researchers Say
Kyle J. Norton
Inflammation is the natural response of the immune system macrophages, the first line of defense in stimulating the production of inflammatory cytokines to protect our body against the infection caused by foreign microorganisms during the acute phase of body damage and injury.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.
Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nervous system, the immune first line of defense stimulates the production of blood platelets to cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.
Acute inflammation usually receded after a few days or weeks depending on the size and damage.
However, in people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
The most common symptoms of acute inflammation that occur within a short period of time such as hours is pain, redness, immobility, swelling, and heat.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
Chronic inflammation is the result of the immune system's inability to kill off all the microorganisms that participated in the acute phase of infection, leading to the formation of autoimmune and chronic inflammatory diseases such as RA and diabetes.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune properties to curb foreign pathogens.
Diseases associated with chronic inflammation asthma are chronic peptic ulcer, tuberculosis, rheumatoid arthritis, and periodontitis.
In finding a natural ingredient for the prevention and treatment of diseases associated with chronic inflammation, scientists compared the anti-inflammatory activity of Chinese herbal extracts, Drynaria baronii (DB), Angelica sinensis (AS), and Cornus officinalis Sieb. et Zucc(CO).
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the tested analysis,
* DB, AS, and CO inhibited nitric oxide (NO) production by lipopolysaccharide (LPS)-activated mouse macrophage-like RAW264.7 cells by inhibition of inducible NO synthase (iNOS) expression at both protein and mRNA levels.
* Furthermore, DB, AS, and CO dose-dependently scavenged the NO radical produced by NOC-7 (a nitric oxide (NO)).
* Moreover, DB and CO effectively inhibited the PGE(2) production by LPS-stimulated RAW264.7 cells, although the extent of inhibition of PGE(2) production was slightly lower than that of NO production.
* More importantly, DB, AS, and CO inhibited cyclooxygenase (COX)-2 expression involved in the initiation of inflammation at both protein and mRNA levels, compared to much lesser extents as compared with that for iNOS expression
* Finally, AS only marginally inhibited the LPS-stimulated PGE(2) production
Taken together, Danggui may be considered an anti-inflammatory remedy for the treatment of chronic inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells by Chu Q1, Hashimoto K, Satoh K, Wang Q, Sakagami H. (PubMed)
Inflammation is the natural response of the immune system macrophages, the first line of defense in stimulating the production of inflammatory cytokines to protect our body against the infection caused by foreign microorganisms during the acute phase of body damage and injury.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.
Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nervous system, the immune first line of defense stimulates the production of blood platelets to cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.
Acute inflammation usually receded after a few days or weeks depending on the size and damage.
However, in people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
The most common symptoms of acute inflammation that occur within a short period of time such as hours is pain, redness, immobility, swelling, and heat.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
Chronic inflammation is the result of the immune system's inability to kill off all the microorganisms that participated in the acute phase of infection, leading to the formation of autoimmune and chronic inflammatory diseases such as RA and diabetes.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune properties to curb foreign pathogens.
Diseases associated with chronic inflammation asthma are chronic peptic ulcer, tuberculosis, rheumatoid arthritis, and periodontitis.
In finding a natural ingredient for the prevention and treatment of diseases associated with chronic inflammation, scientists compared the anti-inflammatory activity of Chinese herbal extracts, Drynaria baronii (DB), Angelica sinensis (AS), and Cornus officinalis Sieb. et Zucc(CO).
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the tested analysis,
* DB, AS, and CO inhibited nitric oxide (NO) production by lipopolysaccharide (LPS)-activated mouse macrophage-like RAW264.7 cells by inhibition of inducible NO synthase (iNOS) expression at both protein and mRNA levels.
* Furthermore, DB, AS, and CO dose-dependently scavenged the NO radical produced by NOC-7 (a nitric oxide (NO)).
* Moreover, DB and CO effectively inhibited the PGE(2) production by LPS-stimulated RAW264.7 cells, although the extent of inhibition of PGE(2) production was slightly lower than that of NO production.
* More importantly, DB, AS, and CO inhibited cyclooxygenase (COX)-2 expression involved in the initiation of inflammation at both protein and mRNA levels, compared to much lesser extents as compared with that for iNOS expression
* Finally, AS only marginally inhibited the LPS-stimulated PGE(2) production
Taken together, Danggui may be considered an anti-inflammatory remedy for the treatment of chronic inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells by Chu Q1, Hashimoto K, Satoh K, Wang Q, Sakagami H. (PubMed)
#Herbal #Bilberry Inhibits Biomarkers Associated with Nonalcoholic Fatty Liver Disease (NAFLD), According to Studies
Kyle J. Norton
People who have an accumulation of triglycerides within hepatocytes that exceeds 5% of liver weight are considered to have nonalcoholic fatty liver disease.
According to the statistics, nonalcoholic fatty liver disease (NAFLD) has risen rapidly over the past few decades and become the most common cause of chronic liver disease in the developing world. The disease affects between 17-30% of the population in Western countries and 2-4% worldwide.
Epidemiologically. obesity, type II diabetes, dyslipidemia, and insulin resistance are the well-known primary causes of NAFLD.
The findings strongly suggested that NAFLD is a geographically related disease associated with dietary patterns.
Dr. Alanna McCarthy, the lead scientist in the examination of diet patterns in the risk NAFLD wrote, "Non-alcoholic fatty liver disease (NAFLD) is a serious consequence of high-fat diet intake and currently affects approximately one-third of the world’s entire population".
And, "Recent evidence suggests that patients with NAFLD have a higher incidence of cardiovascular disease compared to the general population. However, little is known about the link between NAFLD and pathological cardiac remodeling leading to heart disease".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
With an aim to find natural prevention and treatment of non-alcoholic fatty liver disease (NAFLD), researchers investigated the effects of anthocyanin supplementation on insulin resistance and liver injury biomarkers in patients.
74 subjects with NAFLD included in the study were divided into 2 groups in this double-blind, randomized study. Patients received either purified anthocyanin (320 mg/d) derived from bilberry and black currant or placebo for 12 weeks.
During the experiment, the anthocyanin group exhibited a significant decrease in plasma alanine aminotransferase, cytokeratin-18 M30 fragment, and myeloperoxidase, the biomarkers associated with NAFLD, compared to controls.
Compared to the baseline, the anthocyanin group significantly decreased in fasting blood glucose and homeostasis model assessment for insulin resistance, however, these differences were not significant relative to placebo controls.
Not surprisingly, anthocyanin supplementation significantly decreased the 2-hour loading glucose level compared to control, according to the oral glucose tolerance test.
Based on the findings, researchers said, "A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients".
Furthermore, according to the results from the study of ApoE(∗)3Leiden mice fed a Western-type cholesterol-containing diet without (HC) or with 0.1% (w/w) Mirtoselect (HCM), an anthocyanin-rich bilberry extract for 20weeks on diet-induced NASH, Mirtoselect treatment group showed an attenuated HC-induced hepatic steatosis and reduced hepatic cholesteryl ester content.
Furthermore, injection of Mirtoselect also exerted local anti-inflammatory effects in the liver by reducing inflammatory cell clusters and neutrophil infiltration in HCM.
In other words, HCM protected the liver against the HC diet and significantly induced hepatic expression of pro-inflammatory and pro-fibrotic genes associated with the onset of NAFLD.
Dr. Morrison MC, the lead scientist, after taking other factors into account wrote, "Mirtoselect attenuates the development of NASH, reducing hepatic lipid accumulation, inflammation, and fibrosis, possibly mediated by local anti-inflammatory effects associated with reduced accumulation and crystallization of intrahepatic free cholesterol".
Taken altogether, bilberry-processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the treatment of nonalcoholic fatty liver disease, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease by Zhang PW1, Chen FX, Li D, Ling WH, Guo HH. (PubMed)
(2) Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice by Morrison MC1, Liang W2, Mulder P2, Verschuren L2, Pieterman E2, Toet K2, Heeringa P3, Wielinga PY2, Kooistra T2, Kleemann R. (PubMed)
(3) High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease and Cardiac Physiology in Mice by
Alanna McCarthy and Stephen Luckey. (Faseb Journal)
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