#Ginger Protects Our Eyes Against Diabetic #Cataracts by Inhibiting Advanced Dlycation End Products (AGE), Researchers Say

Kyle J. Norton


A cataract is a condition with a decrease in vision, caused by the clouding of the lens in the eye found mostly in older adults. Eye injuries, inflammation, and some other eye diseases are also found to initiate the condition.

According to the statistics provided by the World Health Organization, 51% of world blindness, which represents about 20 million people (2010) worldwide are the result of a cataract. The condition can be reversed by surgery.

Aging cataracts can be classified into 3 primary types, including
* Nuclear sclerotic cataracts

It is the most common type of cataract in the elderly caused by the gradual clouding of the central portion of the lens.

* Cortical cataracts
It is a type of cloudiness that develops in the lens cortex outside the edge of the lens.

* Posterior subcapsular cataracts
It is a type of cataract that begins with a cloudy area on the back surface of the lens.


Epidemiological studies suggested that people who are smokers, have occupations associated with ultraviolet light exposure, diabetes mellitus, and are overweight are susceptible to a higher risk of the disease.

However, some researchers suggested that the widespread cataract in the aging population over the past few decades may be associated with the promotion of a high-fat diet.

Dr. Chung-Jung Chiu, the lead scientist said, "Two major dietary patterns were identified by principal component analysis and named Oriental and Western patterns. The Oriental pattern was characterized by a higher intake of vegetables, legumes, fruit, whole grains, tomatoes, and seafood. The Western pattern was characterized by higher intake of red meat, processed meat, high-fat dairy products, French fries, refined grains, and eggs".

And, "Our data indicate that consuming a Western dietary pattern is significantly associated with increased odds of early nuclear opacity".

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Researchers on finding a natural compound for the treatment of diabetic cataracts caused by advanced glycation end products (AGE) examined ginger anti-AGE activity.


The study included diabetes Wistar-NIN rats induced by intraperitoneal injection of streptozotocin (35 mg/kg body weight) and the control rats received vehicle alone.

In diabetic rats, a set of diabetic animals was given the AIN-93 diet, and another set was given either 0.5 or 3% ginger in their diet for a period of two months.

According to the tested assays, ginger not only delayed the onset but also the progression of cataracts in rats.

Ginger significantly inhibited the formation of various AGE products including carboxymethyl lysine in the eye lens.

Furthermore, the injection of ginger also inhibited the hyperglycemia-induced osmotic stress in the lens.

The results suggested ginger protects the eye against cataracts in rats through a number of mechanisms involved in the development of several pathophysiologies, including diabetic cataracts.


Dr. Saraswat M, the lead scientist wrote at the end of the study, "The results indicated that ginger was effective against the development of diabetic cataract in rats mainly through its antiglycation potential and to a lesser extent by inhibition of the polyol pathway".

Moreover, in the study of oxidative stress and aldose reductase-induced diabetic complications, researchers analyzed the protective effect against diabetic eye complications of purple waxy corn and ginger.


The study included streptozotocin-induced diabetics with blood glucose levels >250 mg·dL(-1) orally given the extract at doses of 50, 100, and 200 mg/kg·BW(-1) for 10 weeks.
All doses of PWCG showed significant inhibition of decreased lens opacity, the levels of oxidative stress Malondialdehyde (MDA), and anti-reflective coating (AR) in the lens of diabetic rats.

PWCG also improved the antioxidant profile in the treated rats.


Most importantly, the anti-retinopathy property of the combined extract was also confirmed by the increased number of neurons in the ganglion cell layer and the thickness of the total retina and retinal nuclear layer in diabetic rats.

Dr. Thiraphatthanavong P, the lead researcher said, "PWCG is the potential functional food to protect against diabetic cataracts and retinopathy. However, further studies concerning toxicity and clinical trials are still essential".


Taken together, ginger processed with a high amount of bioactive compounds may be considered a functional alternative for the prevention and treatment of cataracts, pending the confirmation of a large sample size and multicenter human study.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats by Saraswat M1, Suryanarayana P, Reddy PY, Patil MA, Balakrishna N, Reddy GB. (PubMed)
(2) The combined extract of purple waxy corn and ginger prevents cataractogenesis and retinopathy in streptozotocin-diabetic rats by Thiraphatthanavong P1, Wattanathorn J2, Muchimapura S2, Thukham-mee W2, Lertrat K3, Suriharn B. (PubMed)
(3) American Major Dietary Patterns and Age-related Cataracts by Chung-Jung Chiu, Gary Gensler, and Allen Taylor. (FASEB Journal)

#Phytochemical #Piperine inhibits Proteins Associated with the Apoptosis of #BreastCancer Cells, According to Studies

Kyle J. Norton

Piperine may be the new source of phytochemicals used for the prevention and treatment of breast cancer, some studies suggested.
Breast cancer is a medical condition caused by the alternation of DNA of cells in the breast tissue.

According to the statistic, in 2010, over 250,000 new cases of breast cancer were diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.

Most cases of breast cancer start with cell growth on the surface of the inner lining of the breast tissue. However, at the later stage, malignant cells can infect other healthy cells and tissue far away from the breast through fluids and blood circulation.

The exact causes of breast cancer are unknown. However, the genetic prepositions that link to breast cancer onset have been under intensive study over the last few decades.

Women who inherited the mutated gene BRCA 1 and 2 are associated with over 60% of breast cancer risk compared to women who do not.
Another risk factor associated with breast cancer risk has been mentioned in the scientific community
are a diet high in saturated and trans fat, red meat, and processed foods and low in fruits and vegetables.

Dr. Stoll BA in the Oncology Department, St. Thomas' Hospital, in the study "Breast cancer and the western diet, the role of fatty acids and antioxidant vitamins" said, "An increased ratio of n-3 to n-6 polyunsaturated fatty acids (PUFAs) in the diet inhibits the growth of the rat mammary cancer model" and " There is also evidence that members of then-3 PUFA series can inhibit the growth of human breast cancer cells both in vitro and in explants".

" Clinical trials of supplementary n-3 PUFAs in conjunction with a reduced fat intake have been proposed for breast cancer prevention".

These results suggested women who reduce the intake of saturated and trans fat, red meat, and processed food and replace them with foods that contain a high amount of polyunsaturated fatty acids and antioxidants such as fruits and vegetables are at a reduced risk of breast cancer.

Piperine is a phytochemical alkaloid in the class of organosulfur compounds, found abundantly in white and black pepper, long pepper, etc.

Dr. Do MT and colleagues in the cancer programs at the Chungnam National University, in the finding a natural compound for the treatment of genetic mutation that causes breast cancer, launched an investigation to examine the effect of Piperine, a bioactive component of black pepper, Piper nigrum Linn, molecular mechanisms by which piperine exerts antitumor effects in HER2-overexpressing breast cancer cells.

In HER2-overexpressing breast cancer cells, piperine strongly inhibited proliferation and induced apoptosis through caspase-3 activation and PARP cleavage, the proteins with the function to program cell death.
Piperine also inhibited HER2 gene expression in the promotion of cancer cell proliferation by blockading ERK1/2 signaling. Piperine significantly reduced levels of SREBP-1 and FAS expression which is associated with promoting cancer growth and survival.

Further analysis suggested that piperine suppressed the growth of tumors by stimulating the protein in the induction of cell apoptosis and inhibiting the protein in the promotion of cell proliferation and survival.

Dr.Do MT in the final report of the study said, "Piperine may be a potential agent for the prevention and treatment of human breast cancer with HER2 overexpression".

Moreover, in the study of piperine on the tumor growth and metastasis of mouse 4T1 mammary carcinoma in vitro and in vivo, researchers showed that the application of Piperine (35-280 μmol/L) inhibits the growth of 4T1 cells in time- and dose-dependent manners (the IC(50) values were 105 ± 1.08 and 78.52 ± 1.06 μmol/L, respectively, at 48 and 72 h).

Piperine (70-280 μmol/L) dose-dependently induced apoptosis of 4T1 cells through the proteins that program cell death.

Piperine (140 and 280 μmol/L) significantly increased the percentage of cells in the G(2)/M phase before inducing apoptosis with a reduction in the expression of cyclin B1 in facilitating cell proliferation.

Additionally, Piperine (140 and 280 μmol/L) significantly decreased the expression of MMP-9 and MMP-13 in promoting the cancer cell division and survival and inhibited 4T1 cell migration in vitro.

At the final phase of the experiment, researchers also discovered that injection of piperine (2.5 and 5 mg/kg) dose-dependently suppressed the primary 4T1 tumor growth and injection of piperine (5 mg/kg) significantly inhibited the lung metastasis.

Taken together, piperine, a major pungent alkaloid present in the pepper family may be considered a functional phytochemical for the prevention and combined with the primary therapy for the treatment of breast cancer, depending on large sample size and multicenter human study

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Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)

Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(I) Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells by Do MT, Kim HG, Choi JH, Khanal T, Park BH, Tran TP, Jeong TC, Jeong HG. (PubMed)
(2) Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model by Lai LH, Fu QH, Liu Y, Jiang K, Guo QM, Chen QY, Yan B, Wang QQ, Shen JG.(PubMed)
(3) Breast cancer and the western diet: role of fatty acids and antioxidant vitamins by Stoll BA. (PubMed)

#Herbal #ChasteTreeBerry Induces Oxidation and Apoptosis in Cancer Cells, Reserachers Suggest

Kyle J. Norton

Chaste tree berry is found to exhibit significant anti-cancer activity, a recent study by a renowned study advised.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.

Cancer is a class of diseases characterized by cells growing and multiplying in disordered and uncontrollable ways in our bodies. In the late stage, the cancer cell may travel away from the originated site
to infect other tissues and organs.



According to the Tianjin Institute for Biomedicinal Research, in the evaluated the apoptosis-inducing effect of chaste tree berry, using observation under a light microscope, flow cytometric analysis, and agarose gel electrophoresis, vitexicarpin, a flavonoid found in chaste tree berry significantly inhibited proliferation of human cancer cells lines A2780(human ovarian carcinoma), HCT-15(human, colon, colorectal adenocarcinoma), HT-1080(fibrosarcoma cell line) and K562(Human chronic myeloid leukemia cells), depending to the concentration.

Dr. Wang HY the lead researcher in the study said, "Vitexicarpin induces apoptosis.... via mitochondria(in regulated cell metabolism)-controlled apoptotic pathway".


In support of the above analysis, the crude extract prepared with ethanol from dried ripened Vitex agnus-castus fruits exerted strong cytotoxic effects against cancer cell lines of human uterine cervical canal fibroblast (HCF), human embryo fibroblast (HE-21), ovarian cancer (MCF-7), cervical carcinoma (SKG-3a), breast carcinoma (SKOV-3), gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), and small cell lung carcinoma (Lu-134-A-H) cells.

The inhibition of the extract is attributed to the effect on cell death through apoptosis and increased intracellular oxidation in the tumor cells.

Other researchers suggested that the cytotoxic effects. of Chaste tree, berry may be involved in various aspects, including the JNK (apoptosis) pathway. as indicated in the new native lignan VB6 study.

Taking together, there is no doubt, that chaste tree berries may be considered a valuable chemotherapeutic agent for the treatment of various types of cancer, depending on further evaluation.


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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including world wide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway].[Article in Chinese] by Wang HY1, Cai B, Cui CB, Zhang DY, Yang BF.(PubMed)
(2) Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth by Ohyama K1, Akaike T, Hirobe C, Yamakawa T.(PubMed)
(3) Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway by Zhou J1, Hu H, Long J, Wan F, Li L, Zhang S, Shi YE, Chen Y.(PubMed)

#Greentea and GABA #Greentea (GGT) Reduce Symptoms and Risk of Depression, According to Studies

Kyle J. Norton

Green tea is found to have a psychological effect on patients with depression, a renowned institute study suggested.

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, or an illness, affecting the way you eat, sleep, and the way you feel about yourself. Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate.

Green tea, a precious drink processes the number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

In a cross-sectional study of the consumption of green tea and coffee ascertained with a validated dietary questionnaire and the amount of caffeine intake estimated from these beverages, green tea consumption is associated with reduced symptoms of depression, depending on the amount of intake.

In comparison to the amount intake of participants, the study also found that participants who consumed ≥4 cups of green tea/d had a 51% significantly lower prevalence odds of having depressive symptoms than those who consumed less than 1 cup/d.

Dr. Pham NM, the lead author in the study said, "Higher consumption of green tea, coffee, and caffeine may confer protection against depression".


In vivo, green tea(GT) and GABA green tea (GGT) also expressed a protective activity against post-stroke depression (PSD), a common consequence of stroke, according to a joint study led by Pavia University.

In a mouse model of post-stroke depression, GGT and GT enhance the activity in the modulation of depressive symptoms through decreased oxidative stress, and increased antioxidant endogenous defenses, including polyphenol, theanine, glutamine, etc......

Furthermore, in the review of Embase, PubMed, and Chinese National Knowledge Infrastructure databases from their inception through August 2014, tea consumption of more than 3 cups a day showed a significant decrease in the risk of depression of 37% (RR = 0.63, 95% CI: 0.55-0.71), in compared to individuals with lower tea consumption and those with higher tea consumption.

Taken together, there is no doubt, that green tea may be used as a functional food in reduced symptoms and risk of depression if consumed daily. However, oral administration of large amounts daily should be taken with care, particularly for people with yin constituents.



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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Sources
(1) Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population by Pham NM1, Nanri A1, Kurotani K1, Kuwahara K1, Kume A1, Sato M2, Hayabuchi H3, Mizoue T1. (PubMed)
(2) Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression by Di Lorenzo A1, Nabavi SF2, Sureda A3, Moghaddam AH4, Khanjani S4, Arcidiaco P5, Nabavi SM2, Daglia M1. (PubMed)
(3) Effect of green tea on reward learning in healthy individuals: a randomized, double-blind, placebo-controlled pilot study by Zhang Q1, Yang H, Wang J, Li A, Zhang W, Cui X, Wang K.(PubMed)

#Coffee Lowers the Risk of #Gout, Researchers Say

Kyle J. Norton

Good News for coffee lovers, coffee consumed daily is associated with reduced risk and treatment of chronic and recurrent gout. a renowned institute proposed.

Gout mostly affects one joint, is an acute and recurrent condition of arthritis as a result of uric acid building up in the blood, inducing joint inflammation.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study led by Central South University, in the review literature of PubMed and EMBASE databases, up to April 2015, out of a total of 11 observational studies (6 cross-sectional, 3 cohort, and 2 case-control studies), coffee consumption showed a significant inverse association with incidence of gout.

The study also found that the efficacy of coffee consumption in reducing the risk of gout showed no significant difference between the highest and the lowest coffee intake in terms of serum uric acid (SUA) level.

Additionally, in the total of 45,869 men with no history of gout at baseline with an intake of coffee, decaffeinated coffee, tea, and total caffeine evaluated in every 4 years, participants in returned questionnaires indicated that increasing coffee intake was (1-3, 4-5, and > or = 6 cups per day) inversely associated with the risk of gout depending to numbers of cups consumed daily.

The related risk of gout incidence in coffee drinkers is as low as .41 in comparison to noncoffee-consumed participants.

Most importantly, the total caffeine levels from all sources, including coffee and tea intake showed no associated risk of gout.

Other researchers, in the finding of gout developed, suggested that coffee intake of 4 to 5 and >/=6 cups daily lower risk of gout compared to no intake (0.26 mg/dl and 0.43 mg/dl respectively) and total caffeine from coffee and other beverages and tea intake were not associated with serum uric acid levels.

Also, according to the data from 14,758 participants ages >/=20 years in the Third National Health and Nutrition Examination Survey (1988-1994), coffee consumption is associated with ameliorated serum uric acid level and hyperuricemia frequency.

Taken together, coffee consumption is associated with attenuated risk and treatment of gout caused by elevated serum uric acid levels, depending on the number of cups taken daily.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all rights reserved.
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) Is coffee consumption associated with a lower risk of hyperuricaemia or gout? A systematic review and meta-analysis by Zhang Y1, Yang T1, Zeng C1, Wei J2, Li H1, Xiong YL1, Yang Y1, Ding X1, Lei G1.(PubMed)
(2) Coffee consumption and risk of incident gout in men: a prospective study by Choi HK1, Willett W, Curhan G.(PubMed)
(3) Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey by Choi HK1, Curhan G.(PubMed)

#Cabbage #Extract Inhibits CardiovascularDisease Agaisnt Oxidative Stress, Researchers Suggest

Kyle J. Norton

The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also causes long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

Dr. Ercal N, the lead author in the study of the relation of toxic metals and oxidative stress, wrote, "Antioxidants may play an important role in abating some hazards of heavy metals. In order to prove the importance of using antioxidants in heavy metal poisoning, pertinent biochemical mechanisms for metal-induced oxidative stress".

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative bursts from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Liver oxidative stress markers such as serum MDA refer to oxidative stress in the liver tissues caused by the overexpression of free radicals or reduced levels of antioxidant enzymes in the liver.


Dr. Halina Cichoż-Lach, the lead scientist said, "Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases.".

And, "Hepatocytic proteins, lipids, and DNA are among the cellular structures primarily affected by ROS and reactive nitrogen species. The process results in structural and functional abnormalities in the liver".

In other words, liver oxidative stress over the long-term induced damage of proteins, and lipid and alternation of cell DNA can lead to liver diseases, including cancer.

Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

In finding a natural wholefood for the treatment of cardio-diseases, researchers examined the effects of cabbage extract on oxidative stress in H9c2 cardiomyoblasts.


Based on the results of the experiment,* Cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects.

* Cabbage extract suppressed ROS production and increased expression of antioxidant proteins (SOD-1, catalase, and GPx).

* Cabbage extract also inhibited apoptotic responses and activation of MAPK proteins in initiating cellular response in oxidative stress-exposed H9c2 cells.


* Cabbage extract preserved mitochondrial functions upon oxidative stress.

Based on the results, researchers wrote, "Cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".

Taken together, cabbage may be used to treat oxidative stress-induced cardiovascular diseases, pending confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea var. capitata) Protects against H2o2-induced oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (PubMed)
(2) Oxidative stress as a crucial factor in liver diseases by Halina Cichoż-Lach and Agata Michalak (PMC)

#Greentea #Polyphenols (GTP) Supplement and/or Tai Chi Show a Protective Effect on Bone health, Reserachers Show

Kyle J. Norton

Evidence from laboratory studies opinionated, that regular drinking of green tea improved bone health and reduced the risk of osteoporosis and fractures.

Bone health is measured by bone mineral density which has a direct influence on the risk of osteoporosis and fractures.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will benign the problem.

According to the Texas Tech University Health Sciences Center, green tea lovers have a reduced risk of lower bone mineral density due to its bioactive components with bone-protective properties.


The study also found that regular green tea drinking promotes bone health in bone mineral loss menopausal women through increased bone mass, thus reducing the risk of osteoporosis, a common disease in the aging population.


Furthermore, the intake of green also protected the early onset of bone mineral loss in obese subjects.

Another study conducted by the same group of researchers also stated the bone density protective effect of green tea may involve the bioactive components' effects in decreasing the risk of fracture by supporting osteoblastic activities while suppressing osteoclastic activities as well as attenuating oxidative stress in promoting healthy levels of bone mineral density.

In the postmenopausal osteopenic women study, green tea with an optimized dose of polyphenols showed an enhanced osteoprotective efficacy in improved bone mass, microarchitecture integrity, and bone strength observed through the advanced imaging technology.


Dr, Shen CL, the lead author in the studies said, " Tea polyphenols enhance osteoblastogenesis and suppress osteoclastogenesis in vitro" and "Animal studies reveal that intake of tea polyphenols have pronounced positive effects on bone as shown by higher bone mass and trabecular bone volume, number, and thickness and lower trabecular separation via increasing bone formation and inhibition of bone resorption, resulting in greater bone strength".


Promisingly, in a total study of 171 postmenopausal osteopenic women to compare the efficacy of green tea polyphenols (GTP) supplement and/or Tai Chi in the risk of osteoporosis, randomly assigned to four groups: (1) placebo (500 mg starch/day), (2) GTP (500 mg GTP/day), (3) placebo + TC (placebo plus TC training at 60 min/session, three sessions/week), and (4) GTP + TC (GTP plus TC training).for 6 months, intake of green and tai chi exercise groups increased bone-specific alkaline phosphatase(bone protective glycoprotein found on the surface of osteoblasts) and improved BAP/(tartrate-resistant acid phosphatase, osteoclast increased risk of bone turnover)/TRAP ratio.

Additionally, the group that received green tea showed significantly improved muscle strength in postmenopausal women with osteopenia.


Taken together, green tea may be served as a functional food to protect bone mineral density in all people with/ without risk of osteoporosis.


Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Sources
(1) Green tea and bone health: Evidence from laboratory studies by Shen CL1, Yeh JK, Cao JJ, Chyu MC, Wang JS. (PubMed)
(2) Green tea and bone metabolism by Shen CL1, Yeh JK, Cao JJ, Wang JS. (PubMed)
(3) Tea and bone health: steps forward in translational nutrition by Shen CL1, Chyu MC, Wang JS.(PubMed)
(4) Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial by Shen CL1, Chyu MC, Yeh JK, Zhang Y, Pence BC, Felton CK, Brismée JM, Arjmandi BH, Doctolero S, Wang JS. (PubMed)