#Greentea Inhibits the Onset of #Asthma Through its Anti-Inflammatory Activity, Researchers Say

Kyle J. Norton

Green tea may be a potential therapeutic functional food for the prevention and treatment of asthma, a chronic inflammatory disease, touching people of all ages, particularly in children, a renowned institute suggested.

Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will solve the problem.

According to the joint study led by the Ben Gurion University of the Negev, Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), a flavonoid found in green tea exhibited anti-oxidant/anti-inflammatory effects against various diseases, including asthma.

The study also demonstrated the function of Kaempferol in reducing oxidative stress through scavenging free radicals and superoxide radicals effects as well as preserving the activity of various antioxidant enzymes in attenuating the production of pro-inflammatory cytokines.

In fact, evidence from in vitro and in vivo assays postulated that aqueous fraction of green tea also exerted anti-asthmatic signaling activity in the ovalbumin-induced asthmatic model.

Furthermore, in the study of mice-induced asthma by ovalbumin, an aqueous extract of green tea displayed a potent anti-asthmatic activity by increasing the expression level of tumor necrosis factor-beta, (a protein involved in the production of one of the inflammatory cytokinin the acute phase) and interferon-gamma in the displacement of immune function against microbial infection and decreased expression of anti-asthmatic cytokines in the lung.

More importantly, green tea alleviated asthmatic symptoms by increasing the expression of Th1 cell-in, which regulated the production of interferon-gamma and interleukin (IL)-2, proinflammatory cytokines, and tumor necrosis factor.

Promisingly, another green tea constituent, namely Chafuroside A (CFA), water-soluble flavone C-glycoside, in experimental asthma/chronic obstructive pulmonary disease (COPD)-rat model, treatment with Chafuroside A at 0.5mg/kg, 1.0mg/kg could attenuate inflammatory symptoms and ameliorate antigen-induced airway inflammation, respectively.

Dr., Onoue S, the lead author in the above study said, " A self-assembled micellar (SAM) formulation might be an efficacious approach for enhancing the therapeutic potential of CFA for treatment of inflammatory diseases".

Unfortunately, there are few reports suggesting that green tea-induced asthma in tea-sensitive patients, as epigallocatechin gallate induced histamine release through IgE-mediated response.

Taken together, there is no doubt that green tea may be considered a functional food for the prevention and treatment of asthma, but people with tea-sensitive syndrome should avoid drinking green tea unless with the approval of related field specialists.



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Sources
(1) Kaempferol, a potential cytostatic cure for inflammatory disorders by Rajendran P1, Rengarajan T1, Nandakumar N2, Palaniswami R3, Nishigaki Y1, Nishigaki I4.(PubMed)
(2) An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers by Heo JC1, Rho JR, Kim TH, Kim SY, Lee SH.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)

#Healthyfood #Onion and #Garlic Reduce the Risk of #PancreaticCancer, Scientists Reveal

Kyle J. Norton

The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen.
The gland not only plays a critical role in aiding the digestive system to break down carbohydrates, proteins, and lipids by secreting pancreatic juice to the small intestine but also regulates the production of the hormone insulin to convert glucose to energy from the bloodstream.


Pancreatic cancer is a chronic medical condition caused by cell growth in the pancreas's innermost layer.

Pancreatic cancer found in the ducts (an exocrine component of the pancreas) that carry pancreatic juices with cancer of an epithelium that originates in glandular tissue accounts for over 75 - 90% of all cases of pancreatic cancers.

At the advanced stage, cancerous cells from the primary pancreas can also travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.


According to the statistics provided by the American Cancer Society, in 2019, approximately 56,770 Americans including 29,940 men and 26,830 women will be diagnosed with pancreatic cancer and pancreatic cancer will also cause the death of 45,750 Americans including 23,800 men and 21,950 women.

And the average lifetime risk of pancreatic cancer is about 1 in 64.

The most common symptoms of pancreatic cancer are
* Back pain is caused tumor growing in the back of the pancreas.

* Unexplained weight loss
Any unintentional weight loss over 10% may be a symptom of cancer.

* Loss of appetite
This is a general and common symptom in all forms of cancer.

* Pain and discomfort in the stomach area are a result of an oversized tumor that presses on the nerves in the area.

* Jaundice is a result of the oversized tumor that blocks the bile duct, causing bile back up to the liver.

* Fat in stool increase is a result of reduced bile that digests fat to the digestive system.


If you experience some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the possibility.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

With an aim to find a potential compound for the treatment of pancreatic cancer, researchers conducted a population-based case-control study to investigate the association between vegetables and fruits and pancreatic cancer.

According to the results of 532 cases and 1,701 age- and sex-matched controls completed direct interviews between 1995 and 1999, onion showed a related risk ratio of 0.46 compared to 0.78 for citrus fruits and juice, 0.63 for dark leafy vegetables, 0.76 for cruciferous vegetables, 0.59 for yellow vegetables, 0.56 for carrots, 0.51 for beans.


In other words, the risk of pancreatic cancer is significantly lower in onion consumption compared to other healthy vegetables and fruits.


More precisely, including onion and garlic in your diet, the risk of pancreatic cancer was 0.49 (0.36-0.68) for more than nine servings per day compared to those of less than five servings per day of total vegetables and fruits combined.

The results strongly suggested that onion and garlic have a much stronger effect on pancreatic cancer compared to other fruits and vegetables.

Taken together, onion used alone or combined with other fruits and vegetables may be considered a remedy for the prevention and treatment of pancreatic cancer, pending the confirmation of the larger sample size and multicenter human study.



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Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area by Chan JM1, Wang F, Holly EA. (PubMed)

#Herbal #Bilberry Inhibits #Receptors Involved in #Gene Expression Against Lipid Accumulation and Oxidative-Stress, Researchers Suggest

Kyle J. Norton

Oxidative stress occurs when the ratio of the levels of free radicals and antioxidants is imbalanced. In other words, oxidative stress is a result caused by either overexpression of free radicals or depletion of antioxidant enzymes produced by the host.

Free radicals are an unstable atom with a lone electron in the outer ring. Therefore, in order to become stable, free radicals must steal or donate an electron from other stable atoms, leading to a chain reaction that is highly reactive and can be stopped until all single electron is paired or inhibited by antioxidants.

Antioxidants are stable atoms that inhibit oxidation.

Free radical exists in and outside our body. Externally, the air we breathe, the food we eat environmental toxins, and internally, the cell's metabolism, all contribute to the production of free radicals.

On the other hand, antioxidants can either be produced by the body internally or induced by the consumption of antioxidant-rich externally.

Under normal conditions, in a healthy individual, the production of antioxidant enzymes by the body is more than enough to counter the levels of free radicals in the body. However, for people with a weakened immune system or immature immune system, the intake of dietary sources of antioxidant-rich foods may be necessary.

Maintaining healthy levels of antioxidants in the body is the best way to prevent diseases associated with oxidative stress, including atherosclerosis, cancer, diabetes, and rheumatoid arthritis.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.

In the urgency to discover a bioactive compound for the treatment of diseases associated with oxidative stress, researchers examined the anti-adipogenic effect of the polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L., and cranberry Vacciniummacrocarpon Aiton fruits.

According to the tested assays, treatment with the extract (25-100 μg/mL) significantly decreased lipid accumulation and reactive oxygen species generation in adipocytes without showing cytotoxicity.

The extract at a concentration of 100 μg/mL suppressed adipogenesis and lipogenesis by inhibiting the receptors involved in gene expression.

Moreover, the extract also exerted the anti-adipogenic effect by a significant increase in the expression of adiponectin (4.4-fold) and decreased leptin expression (90%) made by adipose cells.


In the study to investigate the antihyperglycemic effects of four extracts obtained from leaves and fruits of Vaccinium myrtillus and Vacciniumcorymbosum in diabetic rats randomly divided into seven equal groups: NC-normal control, DC-diabetic control, PC-positive control treated with metformin, VML-received V. myrtillus leaf extract, VMLF-received VML, and fruit extract, VCL-received V. corymbosum leaf extract, and VCLF-received VCL and fruit extract, researchers found that according to the Bodyweight and glucose levels monitored every second week and after 8 weeks of treatment, serum glucose, insulin, and malondialdehyde measurement

* The treated group showed no significant decrease in weight compared to a decrease in body weight in all diabetic groups in the first weeks.

* VML, VMLF, and VCLF groups demonstrated a decrease in blood glucose levels compared to the increase in the DC, PC, and VCL groups.

* Additionally, serum insulin and glucose levels at the end of the experiment were lower in VML, VMLF, and VCLF groups compared to other unimproved groups.

* More importantly, V. myrtillus extracts prevented the development of cataracts compared with the DC group (P < .05).


The findings suggested that bilberry processes antioxidative stress activity against the onset of obesity and retinal degenerative disease.


Taken together, bilberry-processed abundantly bioactive compounds may be considered a functioning remedy for the prevention and treatment of diseases associated with oxidative stress, pending the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Inhibitory activity of chokeberry, bilberry, raspberry, and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells by Kowalska K1, Olejnik A1, Szwajgier D2, Olkowicz M. (PubMed)
(2) Vaccinium Extracts as Modulators in Experimental Type 1 Diabetes by Ştefănescu Braic R1, Vari C2, Imre S3, Huţanu A4, Fogarasi E5, Todea T6, Groşan A2, Eşianu S1, Laczkó-Zöld E1, Dogaru M. (PubMed)

#Cinnamon Supplementation Is Associated with Glycemic Control in Diabetes and its Complications, Researchers Say

Kyle J. Norton

Intake of cinnamon is found to improve fasting glucose, glucose tolerance, and insulin sensitivity in women with insulin resistance associated with polycystic ovary syndrome.

Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as an anti-fungal and bacterial level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

Cinnamaldehyde, in the animal study found in the husk of Cicer arietinum L. Monosaccharide, exhibited antioxidant effects in reduced 29% of free radical expression and glucolipid levels through its action on multiple signaling pathways including cell cycle arrest and anti-pro-inflammatory properties.

In vivo and in vitro, administered orally cinnamic acid and cinnamaldehyde lower acute blood glucose and improve glucose tolerance, through stimulating insulin secretion in isolated islets, according to the joint study led by the University of Karachi.

In a 16-week double-blind randomized control trial of 116 individuals with metabolic syndrome, dietary intervention groups with the administration of cinnamon [6 capsules (3 g) daily], significantly improved all components of metabolic syndrome in a sample of Asian Indians in north India.

Dr. Gupta Jain S lead author of the researchers said,"Significantly greater decrease [difference between means, (95% CI)] in fasting blood glucose (mmol/L) [0.3 (0.2, 0.5) p = 0.001], glycosylated hemoglobin (mmol/mol) [2.6 (0.4, 4.9) p = 0.023], waist circumference (cm) [4.8 (1.9, 7.7) p = 0.002] and body mass index (kg/m2 ) [1.3 (0.9, 1.5) p = 0.001] was observed in the cinnamon group compared to placebo group".

Other researchers in the study of cinnamon's (Cinnamomum cassia) anti-diabetic properties on obese patients also suggested, that its effectiveness in increasing the lipid storage capacity of white adipocytes and increasing the fatty acid oxidation capacity may be due to activities of some other components of cinnamon (Cinnamomum cassia) in the prevention of obesity-induced type II diabetes


Although cinnamon (Cinnamomum sp) has been shown to express good glycemic control to patients with type 2 diabetes mellitus (T2DM), the intake of cinnamon supplements and whole herb should only be given by the qualified herbal doctor to achieve a greater health effect without side effects.

According to traditional Chinese medicine, cinnamon is a very hot herb, and overdoses may induce toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Chromium and polyphenols from cinnamon improve insulin sensitivity. by Anderson RA1(PubMed)
(2) Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics, and safety by Zhu R1, Liu H1, Liu C2, Wang L1, Ma R1, Chen B1, Li L1, Niu J1, Fu M3, Zhang D4, Gao S5.(PubMed)
(3) Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro by Hafizur RM1, Hameed A2, Shukrana M3, Raza SA2, Chishti S2, Kabir N4, Siddiqui RA2. (PubMed)
(4) Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double-blind control trial by Gupta Jain S1, Puri S1, Misra A2, Gulati S3,4, Mani K5.(PubMed)
(5) Stimulatory Effects of Cinnamon Extract (Cinnamomum cassia) during the Initiation Stage of 3T3-L1 Adipocyte Differentiation by Lee SG1, Siaw JA2, Kang HW3.(PubMed)

#Lyophilized Bilberries or Blueberries Enhance Locomotion In Patients with Neurodegenerative Disease, Researchers Reveal

Kyle J. Norton

Locomotion is the ability to move from one place to the other. In humans, locomotion controlled by the cerebellum is a complex process that requires the integration of central and peripheral nervous signaling coordinated by the muscles.
In other words, every time you move any part of the body, the cerebellum fires into action.

Damage to the cerebellum of the brain has been found to induce difficulty with balance, coordination, and fine motor skills in patients.


Besides neurodegenerative diseases, alcohol abuse, certain medications, stroke, tumors, cerebral palsy, brain degeneration, and multiple sclerosis are the most common risk factors that can affect brain locomotion control.

In conventional medicine, depending on the causes that affect the locomotion, adaptive devices may be introduced to maintain independence. Other therapies such as physical, occupational, and speech therapy with moderate exercise have been found to be helpful.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.

In finding a potential compound for the improvement of locomotion in patients with neurodegenerative disease, researchers examined the possible effects of prolonged administration of lyophilized Vaccinium berries (blueberry, bilberry) on cognitive performance against the incidence of degenerative disorders.

Mice selected for the study were observed by step-down inhibitory avoidance, open field, elevated plus-maze, and radial maze tasks. The lyophilized berries were administered for 30 days before the first training.

According to the tested assays, lyophilized berries significantly enhanced locomotion by increasing the number of crossings in the first exposure to the open field.

Additionally, short-term treatment with lyophilized berries also improves rat performance on the elevated plus-maze task.

In other words, lyophilized berries inhibited the neuro deficits associated with inactivity behavior such as anxiety.


Taken together, bilberry-processed abundantly bioactive compound anthocyanoside may be considered a functioning remedy for the improvement of locomotion in patients with neurodegenerative diseases, pending the validation of a larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Effect of lyophilized Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)

#Cranberry Inhibits Brain Cell Stress Associated with the Risk of β-Amyloid Aggregation, Researchers Say

Kyle J. Norton

Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, leading to the onset of Alzheimer's disease.
Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.

Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.


According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.

Alzheimer's disease is caused by a combination of genetic, lifestyle, and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic predisposition. Patients with such mutated genes on chromosomes 21, 14, and 1 are virtually guaranteed to develop the disease.

More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.

Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies, or social life. Alzheimer's gets worse over time, and it is fatal.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia.

Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

In finding a potential compound for the treatment of mental disorders, researchers examined the effect of cranberry supplementation on β-amyloid aggregation.

According to tested analysis, the cranberry protected the neurons by mediating Aβ toxicity alleviation required heat shock transcription factor (HSF)-1 rather than DAF-16, and was associated with cellular stress.

In other words, cranberry supplementation reduced Aβ toxicity-induced brain cell stress by reducing the transactivity of HSF-1 in an IIS-dependent manner.

More precisely, HSF-1 plays a pivotal role in maintaining proteostasis, a process that regulates proteins within the cell in order to maintain the neuron cellular health involved in oxidative stress.

Based on the findings, researchers aid, "(cranberry) elucidated the mechanism whereby cranberry attenuated Aβ toxicity in C elegans and stressed the significance of proteostasis in the prevention of age-related diseases from a practical point of view.".


Taken together, cranberry may be considered a remedy for the treatment of AD, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 in Caenorhabditis elegans Model of Alzheimer’s Disease by
Hong Guo, Min Cao, Sige Zou, 4 Boping Ye, and Yuqing Dong. (PMC)

#Bromelain Enzyme #Supplement Inhibits Symptoms and Improves Quality of Life in Children with Cystic Fibrosis, Researchers Find

Kyle J. Norton

Cystic fibrosis (CF) is a genetic preposition that leads to diseases mostly in the lungs in children and young adults.
Most cases of CF have been found to cause persistent infection in the lungs, leading to the destruction of lung tissues and reduced lung function, depending on the severity of the condition.

The most common complication of CF is difficulty digesting fats, proteins, and nutrient absorption, progressive lung damage caused by ongoing infections chronic low-grade inflammation, and CF-related diabetes.

According to statistics provided by the Canadian Cystic Fibrosis Foundation, approximately 1 in every 3,600 children born in Canada has CF.

In age perspective,
* 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.


* More than 47% of all Canadians with CF are over the age of 18 years.

* As of 2002, the median age of survival of Canadians with CF is 37 years of age.


The most common symptoms of CF are persistent cough with productive thick mucous, wheezing and shortness of breath, frequent chest infections, weight loss or failure to gain weight, infertility in men, and decreased fertility in women.

Conventionally, as of today, there is no cure for CF. Medications are focusing on reducing symptoms and improving quality of life, including
* Antibiotics for the treatment of lung infections.



* Anti-inflammatory medications to protect the lung airways.


* Medication to reduce cough up the mucus

* Inhaled medications to keep your airways open by relaxing the muscles around your bronchial tubes

* Medication to help the digestive tract in absorbing nutrients

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

In finding a natural compound for the treatment of cystic fibrosis, researchers compared identical capsules half-filled with mini-tablets of a new high lipase preparation in a randomized double-blind crossover study in children with cystic fibrosis.

All children who participated in the study received his/her usual number of capsules and the same dose of lipase during each period of the study.

According to the results from the 18 children who completed the study, the pancreatic enzyme applied in the high lipase preparation showed fewer gastrointestinal symptoms compared to the low lipase group.

Compared to the baseline, the pancreatic enzyme group showed a significant improvement in fat absorption and a reduction in fecal fat output.


Fecal energy loss was also improved in the treatment group.

Based on the findings, researchers at the St James's Hospital wrote, " (The) half-filled capsules of the new high lipase preparation are more effective than the standard preparation and it is likely that filled capsules would allow patients to use fewer than half the number of pancreatic enzyme capsules".

Taken together, bromelain may be considered a supplement for the prevention and treatment of symptoms of cystic fibrosis, pending the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements by Croft NM1, Marshall TG, Ferguson A. (PubMed)
(2) A double-blind lipase for lipase comparison of a high lipase and standard pancreatic enzyme preparation in cystic fibrosis by Bowler IM1, Wolfe SP, Owens HM, Sheldon TA, Littlewood JM, Walters MP. (PubMed)