Kyle J. Norton
The lipoprotein profiles or lipoprotein parameters are a general term comprised of the traditional lipoprotein profile including total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride.
Total cholesterol is the total amount of cholesterol in your blood, including the low-density lipoprotein (LDL, or “bad”) cholesterol and high-density lipoprotein (HDL, or “good”) cholesterol.
The healthy ratio of blood cholesterol is less than 4 of the low-density lipoprotein to 1 of the high-density lipoprotein.
Where low-density lipoprotein is produced by the liver or from food sources needed for the cells to build strong membranes, and produce steroid hormones, vitamin D, and bile to aid the digestive system in absorbing nutrients and fluids.
And high-density lipoprotein produced by the liver or from external sources is needed to return the low-density lipoprotein back to the liver.
Triglycerides, an important measure of heart health is the fat in the blood caused by the over-consumption of foods containing fat, carbohydrates, and simple sugars.
Factors that affect your lipoprotein profiles can be unpreventable including age, gender, race, and genetic preposition and preventable such as diet, weight, physical activity, and smoking.
Some researchers suggested that people who are obese are at a substantially higher risk of poor lipoprotein profiles.
Dr. Pandolfi C, the lead scientist wrote, "Lipid pattern has resulted in overlapping both in the two studied populations and in the two subgroups of pre-and postmenopausal women, while greater concentrations of Lp(a), (p < 0.001) and t-PA (p < 0.05) have been found in obese populations vs controls".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
In the urgency of finding natural sources of plant-based compound for the prevention of cardiovascular disease (CVD), researchers investigated regular consumption of bilberries in CVD risk reduction.
Women (n=25) and men (n=11) selected for the study received 150 g of frozen stored bilberries 3 times a week for 6 weeks. All parameters associated with the risk of CVD were measured by standard assays.
In both sexes, the consumption of bilberries led to a decrease in the parameters of lipoprotein profiles, including total cholesterol, LDL-C, TG, and a positive increase in HDL-C.
However, in men, additionally, favorable changes were observed in total cholesterol (P=.004), reduced oxidative stress, and HDL-C, but an increase in LDL-C compared to the women group.
In other words, the regular intake of bilberries can be important to reduce CVD risk, by promoting a decrease of LDL-C/TG and an increase of HDL-C.
Furthermore, in order to reveal more information about bilberry against CVD risk, researchers compared consumed dried sea buckthorn berries (SBs), sea buckthorn oil (SBo), sea buckthorn phenolics ethanol extract mixed with maltodextrin (SBe+MD, 1:1), or frozen bilberries on metabolic profiles.
In a total of 80 women selected to complete this randomized crossover study for 30 d, all interventions induced a significant effect on the overall metabolic profiles, particularly in lipid parameters observed both in participants who had a metabolic profile that reflected higher cardiometabolic risk at baseline (group B) and in participants who had a lower-risk profile (group A).
However, the bilberries treatment group caused beneficial changes in serum lipids and lipoproteins in group B, whereas the opposite was true in group A.
The finding clearly suggested bilberries modulated the parameters of lipids and lipoproteins depending on the risk of CVD.
Dr. Larmo PS, after taking into account co and confounders wrote, "Berry intake has overall metabolic effects, which depend on the cardiometabolic risk profile at baseline (including bilberry)".
Taken together, bilberry may be considered a functional remedy for the promotion of lipid-protein profiles in reducing the risk of CVD, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovascular disease by inducing favorable changes in lipoprotein profiles by Habanova M1, Saraiva JA2, Haban M3, Schwarzova M4, Chlebo P5, Predna L6, Gažo J7, Wyka J. (PubMed)
(2) Effects of sea buckthorn and bilberry on serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized crossover trial by Larmo PS1, Kangas AJ, Soininen P, Lehtonen HM, Suomela JP, Yang B, Viikari J, Ala-Korpela M, Kallio HP. (PubMed)
(3) [Lipoprotein(a), parameters of lipid metabolism and hemostasis in obese patients].[Article in Italian] by Pandolfi C1, Pellegrini L, Dedè A, Lo Vecchio M, Mercantini F. (PubMed)
Tuesday, 19 September 2023
#Sodium Ferulate and #Polysaccharides Fraction Found in Herbal #Angelica Induce a Strong and Positive Effect on #Osteoarthritis
Kyle J. Norton
Osteoarthritis (OA) is a form of arthritis, found in the general term of musculoskeletal disorders (MSDs) characterized by wear and tear on joints.
The chronic and medical condition affects over 25 million people in the United States alone.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty in moving the joint or joints. Therefore one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), compared to other types of arthritis.
Furthermore, the pain usually gets worse in a change of weather, at night, and in advanced diseases, and the pain can occur even at rest.
In contrast to the general belief, osteoarthritis only damages the joints of the hands and knees, but also causes inflammation of the joints in your hips and spine.
The condition is a slow development disease, often starting in the 40s and 50s, and affects almost all people to some degree by age 80.
The common risk factors of osteoarthritis are aging, gender, improper healing of injured joints at a young age, obesity, and bone deformity. However, people who have a job with tasks that place repetitive stress on a particular joint are associated with the onset of osteoarthritis in most industrial countries.
According to the statistics from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% of men and 13% of women.
Epidemiological strongly suggest that obese and overweight have a strong impact on the weight-bearing joints, the genetic preposition of a patient can make such a patient more susceptible to the disease compared to others who do not. People with a joint injury that did heal properly in a younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting, or other movements, and the increase in age are associated with the increased risk of the onset of the disease.
In finding a natural ingredient for the prevention and treatment of aging-related diseases, scientists examined the angelica phytochemical, sodium ferulate, and a polysaccharide fraction on osteoarthritis animal models or in human chondrocytes stimulated by the proinflammatory cytokine, Interleukine-1β.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the results of the experiment,* Sodium ferulate found in angelica exhibited marked anti-inflammatory and anti-apoptotic properties by inhibiting the TNF/TNFR signal transduction pathway associated with inflammation and autoimmunity.
* On another hand, the polysaccharide fraction which contains a mixture of various carbohydrates was found to promote proteoglycan biosynthesis in the cartilage matrix by stimulating the activity of the UDP-glycosyltransferases that synthesize the chondroitin sulfate chains of aggrecans.
In other words, both chemical compounds demonstrated strong protective effects against osteoarthritis through different mechanisms.
based on the findings, researchers said, "the combined action of sodium ferulate and polysaccharides fraction would prevent cartilage destruction in osteoarthritis and favor cartilage repair".
Taken together, herbal angelica may be considered an antioxidant remedy for the treatment of osteoarthritis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis and osteoarthritis: a natural therapeutic link? by Magdalou J1, Chen LB2, Wang H3, Qin J2, Wen Y2, Li XJ3, Shang L3, Li J. (PubMed)
Osteoarthritis (OA) is a form of arthritis, found in the general term of musculoskeletal disorders (MSDs) characterized by wear and tear on joints.
The chronic and medical condition affects over 25 million people in the United States alone.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty in moving the joint or joints. Therefore one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), compared to other types of arthritis.
Furthermore, the pain usually gets worse in a change of weather, at night, and in advanced diseases, and the pain can occur even at rest.
In contrast to the general belief, osteoarthritis only damages the joints of the hands and knees, but also causes inflammation of the joints in your hips and spine.
The condition is a slow development disease, often starting in the 40s and 50s, and affects almost all people to some degree by age 80.
The common risk factors of osteoarthritis are aging, gender, improper healing of injured joints at a young age, obesity, and bone deformity. However, people who have a job with tasks that place repetitive stress on a particular joint are associated with the onset of osteoarthritis in most industrial countries.
According to the statistics from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% of men and 13% of women.
Epidemiological strongly suggest that obese and overweight have a strong impact on the weight-bearing joints, the genetic preposition of a patient can make such a patient more susceptible to the disease compared to others who do not. People with a joint injury that did heal properly in a younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting, or other movements, and the increase in age are associated with the increased risk of the onset of the disease.
In finding a natural ingredient for the prevention and treatment of aging-related diseases, scientists examined the angelica phytochemical, sodium ferulate, and a polysaccharide fraction on osteoarthritis animal models or in human chondrocytes stimulated by the proinflammatory cytokine, Interleukine-1β.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the results of the experiment,* Sodium ferulate found in angelica exhibited marked anti-inflammatory and anti-apoptotic properties by inhibiting the TNF/TNFR signal transduction pathway associated with inflammation and autoimmunity.
* On another hand, the polysaccharide fraction which contains a mixture of various carbohydrates was found to promote proteoglycan biosynthesis in the cartilage matrix by stimulating the activity of the UDP-glycosyltransferases that synthesize the chondroitin sulfate chains of aggrecans.
In other words, both chemical compounds demonstrated strong protective effects against osteoarthritis through different mechanisms.
based on the findings, researchers said, "the combined action of sodium ferulate and polysaccharides fraction would prevent cartilage destruction in osteoarthritis and favor cartilage repair".
Taken together, herbal angelica may be considered an antioxidant remedy for the treatment of osteoarthritis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis and osteoarthritis: a natural therapeutic link? by Magdalou J1, Chen LB2, Wang H3, Qin J2, Wen Y2, Li XJ3, Shang L3, Li J. (PubMed)
#Casticin Found in #Chastetreeberry Induces Cytotoxicity Agaisnt #Leukemic Cells, Researchers Find
Kyle J. Norton
Oral Administrated ripe fruit of Vitex agnus-castus (Vitex) may reduce the risk of various types of solid tumor cells, particularly leukemia.
Leukemia is a condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the Tokyo University of Pharmacy and Life Sciences, casticin,, the major chemical compound found in extract from the ripe fruit of Vitex agnus-castus (Vitex) exhibited strong cytotoxic activities against leukemia cell lines, HL-60 and U-937 in dose depending manner.
Additionally, the study also expressed an interesting result as the levels of cytotoxicity of Vitex/Casticin were largely attributed to the degree of differentiation of leukemia cells depending on cancer cell line maturity. compared to the HL-60 cell line with a less mature U-937 cell line.
Dr. Kikuchi H, the lead author said, "Casticin accounted for approximately 1% weight of Vitex. Dose-dependent cytotoxicity of Vitex and casticin was observed in both cell lines, and HL-60 cells were more sensitive to the cytotoxicity of Vitex/casticin compared to U-937 cells".
In a further study, casticin, also displayed significant anti-leukemia activity in cells through an expression molecular mechanism. apoptosis and cell cycle arrest were observed through different assays.
The application of casticin yielded a result of cancer cell death at 75.3% at 12 in the G2 phase in tumor cell cycle division, increased and subsequently declined to 27% at 48 h which was an indication of leukemic cell death via apoptosis and mitotic catastrophe.
Another study in support of the above differentiation suggested that the extract from the ripe fruit of Vitex angus-cactus (Vitex), inhibited the leukemia cell lines probably due to other mechanism such as significant decrease levels of intracellular reactive oxygen species (ROS) and level of gp91(phox), an important component of NADPH oxidase, in production of oxidation, and mediated cytotoxicity in HL-60 cells by regulating ROS generation...
Taken together, Chaste tree berry has a significant implication in reduced risk and treatment of leukemia through a number of mechanisms, but intake of large amounts should be taken with care to prevent toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines by Kikuchi H1, Yuan B, Nishimura Y, Imai M, Furutani R, Kamoi S, Seno M, Fukushima S, Hazama S, Hirobe C, Ohyama K, Hu XM, Takagi N, Hirano T, Toyoda H.(PubMed)
(2) Casticin induces leukemic cell death through apoptosis and mitotic catastrophe by Shen JK1, Du HP, Yang M, Wang YG, Jin J.(PubMed)
(3) Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus fruit extract by Kikuchi H1, Yuan B1, Yuhara E1, Imai M1, Furutani R1, Fukushima S1, Hazama S1, Hirobe C2, Ohyama K1, Takagi N3, Toyoda H1.(PubMed)
Oral Administrated ripe fruit of Vitex agnus-castus (Vitex) may reduce the risk of various types of solid tumor cells, particularly leukemia.
Leukemia is a condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the Tokyo University of Pharmacy and Life Sciences, casticin,, the major chemical compound found in extract from the ripe fruit of Vitex agnus-castus (Vitex) exhibited strong cytotoxic activities against leukemia cell lines, HL-60 and U-937 in dose depending manner.
Additionally, the study also expressed an interesting result as the levels of cytotoxicity of Vitex/Casticin were largely attributed to the degree of differentiation of leukemia cells depending on cancer cell line maturity. compared to the HL-60 cell line with a less mature U-937 cell line.
Dr. Kikuchi H, the lead author said, "Casticin accounted for approximately 1% weight of Vitex. Dose-dependent cytotoxicity of Vitex and casticin was observed in both cell lines, and HL-60 cells were more sensitive to the cytotoxicity of Vitex/casticin compared to U-937 cells".
In a further study, casticin, also displayed significant anti-leukemia activity in cells through an expression molecular mechanism. apoptosis and cell cycle arrest were observed through different assays.
The application of casticin yielded a result of cancer cell death at 75.3% at 12 in the G2 phase in tumor cell cycle division, increased and subsequently declined to 27% at 48 h which was an indication of leukemic cell death via apoptosis and mitotic catastrophe.
Another study in support of the above differentiation suggested that the extract from the ripe fruit of Vitex angus-cactus (Vitex), inhibited the leukemia cell lines probably due to other mechanism such as significant decrease levels of intracellular reactive oxygen species (ROS) and level of gp91(phox), an important component of NADPH oxidase, in production of oxidation, and mediated cytotoxicity in HL-60 cells by regulating ROS generation...
Taken together, Chaste tree berry has a significant implication in reduced risk and treatment of leukemia through a number of mechanisms, but intake of large amounts should be taken with care to prevent toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines by Kikuchi H1, Yuan B, Nishimura Y, Imai M, Furutani R, Kamoi S, Seno M, Fukushima S, Hazama S, Hirobe C, Ohyama K, Hu XM, Takagi N, Hirano T, Toyoda H.(PubMed)
(2) Casticin induces leukemic cell death through apoptosis and mitotic catastrophe by Shen JK1, Du HP, Yang M, Wang YG, Jin J.(PubMed)
(3) Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus fruit extract by Kikuchi H1, Yuan B1, Yuhara E1, Imai M1, Furutani R1, Fukushima S1, Hazama S1, Hirobe C2, Ohyama K1, Takagi N3, Toyoda H1.(PubMed)
#Nishamalaki (NA), a Combination of Curcuma Longa and Emblica Officinalis Effectively Prevents the Development of Diabetic Neuropathy
Kyle J. Norton
Diabetic neuropathy is a complication of patients with diabetes associated with nerve damage, ranging from pain and numbness in your legs and feet to problems with your digestive system.
Most cases of diabetic neuropathy are involved in diabetics who have a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart.
Diabetic neuropathy can be classified into 4 main types, including.
* Peripheral neuropathy is the most common type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms.
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs, and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks, or legs.
* Mononeuropathy or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso), or leg.
The exact causes of diabetic neuropathy are totally depending on the type of neuropathy. However, damage of nerves and blood vessels in the affected area has been found to induce over time, uncontrolled high blood sugar.
In other words, diabetic neuropathy is preventable by keeping the blood glucose in the healthy range.
Dr. Michael Greger M.D. FACLM in the article "the best diet for diabetic neuropathy" wrote, "
(By examing) people eating different diets found that nine months or more on a strict plant-based diet appeared to remove the trans fat from their bodies (or at least their butts). Their pain, however, didn’t take nine months to get better—it got better in days".
In the explanation of the results, the researcher continued, "More likely, it was due to an improvement in blood flow. “[N]erve biopsies in diabetics with severe progressive neuropathy…have shown small vessel disease within the nerve. There are blood vessels within our nerves that can get clogged up too. The oxygen levels in the nerves of diabetics were found to be lower than even the levels of oxygenated blood".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic neuropathy researchers examined the turmeric's antioxidant properties, anti-inflammatory, CNS depressant effect, and antibacterial and antifungal properties.
According to the results of the experiment, turmeric inhibited the pathogenesis of diabetic neuropathy by improving the antioxidant in the reduction of the level of oxidative stress associated with the occurrence of the present complication.
Furthermore, turmeric also enhances the anti-inflammatory and antibacterial activity against the spread of infection.
In other words, turmeric inhibits diabetic neuropathy through a number of mechanisms involved in antioxidant, anti-inflammatory, and antibacterial activity.
In order to review more information about the turmeric effect, researchers investigated Nishamalaki (NA), a combination of Curcuma longa and Emblica officinalis in the prevention of diabetic neuropathy.
The study included diabetic neuropathy in type 2 diabetic Wistar rats under treatment for 12 weeks.
Selected rats were randomly divided into group I (Control) vehicle-treated consisting of 6 rats and
group II-VII Diabetic Control, NA low dose, NA High dose, Glibenclamide, Pioglitazone, and Epalrestat respectively.
Diabetes-induced in 36 Wistar rats with Streptozotocin (STZ) (35mg/kg) intraperitoneally followed by High Fat High Fructose diet. After confirmation of the development of diabetes; rats were divided into six groups as the aforementioned division.
Compared to other treatment groups, Nishamalaki (NA) not only controlled hyperglycemia and reduced lipid levels but also effectively prevented the development of diabetic neuropathy.
Taken together, turmeric used alone or combined with other herbal medicines may be considered supplements for the prevention of diabetic neuropathy, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy by Grover M1, Shah K2, Khullar G3, Gupta J1, Behl T. (PubMed)
(2) Evaluation of Effect of Nishamalaki on STZ and HFHF Diet Induced Diabetic Neuropathy in Wistar Rats by Dawane JS1, Pandit VA2, Bhosale MS3, Khatavkar PS. (PubMed)(3) Best Diet for Diabetic Neuropathy. Written By Michael Greger M.D. FACLM on January 1st, 2019
Diabetic neuropathy is a complication of patients with diabetes associated with nerve damage, ranging from pain and numbness in your legs and feet to problems with your digestive system.
Most cases of diabetic neuropathy are involved in diabetics who have a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart.
Diabetic neuropathy can be classified into 4 main types, including.
* Peripheral neuropathy is the most common type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms.
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs, and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks, or legs.
* Mononeuropathy or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso), or leg.
The exact causes of diabetic neuropathy are totally depending on the type of neuropathy. However, damage of nerves and blood vessels in the affected area has been found to induce over time, uncontrolled high blood sugar.
In other words, diabetic neuropathy is preventable by keeping the blood glucose in the healthy range.
Dr. Michael Greger M.D. FACLM in the article "the best diet for diabetic neuropathy" wrote, "
(By examing) people eating different diets found that nine months or more on a strict plant-based diet appeared to remove the trans fat from their bodies (or at least their butts). Their pain, however, didn’t take nine months to get better—it got better in days".
In the explanation of the results, the researcher continued, "More likely, it was due to an improvement in blood flow. “[N]erve biopsies in diabetics with severe progressive neuropathy…have shown small vessel disease within the nerve. There are blood vessels within our nerves that can get clogged up too. The oxygen levels in the nerves of diabetics were found to be lower than even the levels of oxygenated blood".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic neuropathy researchers examined the turmeric's antioxidant properties, anti-inflammatory, CNS depressant effect, and antibacterial and antifungal properties.
According to the results of the experiment, turmeric inhibited the pathogenesis of diabetic neuropathy by improving the antioxidant in the reduction of the level of oxidative stress associated with the occurrence of the present complication.
Furthermore, turmeric also enhances the anti-inflammatory and antibacterial activity against the spread of infection.
In other words, turmeric inhibits diabetic neuropathy through a number of mechanisms involved in antioxidant, anti-inflammatory, and antibacterial activity.
In order to review more information about the turmeric effect, researchers investigated Nishamalaki (NA), a combination of Curcuma longa and Emblica officinalis in the prevention of diabetic neuropathy.
The study included diabetic neuropathy in type 2 diabetic Wistar rats under treatment for 12 weeks.
Selected rats were randomly divided into group I (Control) vehicle-treated consisting of 6 rats and
group II-VII Diabetic Control, NA low dose, NA High dose, Glibenclamide, Pioglitazone, and Epalrestat respectively.
Diabetes-induced in 36 Wistar rats with Streptozotocin (STZ) (35mg/kg) intraperitoneally followed by High Fat High Fructose diet. After confirmation of the development of diabetes; rats were divided into six groups as the aforementioned division.
Compared to other treatment groups, Nishamalaki (NA) not only controlled hyperglycemia and reduced lipid levels but also effectively prevented the development of diabetic neuropathy.
Taken together, turmeric used alone or combined with other herbal medicines may be considered supplements for the prevention of diabetic neuropathy, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy by Grover M1, Shah K2, Khullar G3, Gupta J1, Behl T. (PubMed)
(2) Evaluation of Effect of Nishamalaki on STZ and HFHF Diet Induced Diabetic Neuropathy in Wistar Rats by Dawane JS1, Pandit VA2, Bhosale MS3, Khatavkar PS. (PubMed)(3) Best Diet for Diabetic Neuropathy. Written By Michael Greger M.D. FACLM on January 1st, 2019
#Bromelain Inhibits Platelet Aggregation Associated with Levels of ADP and TRAP-6, Researchers Say
Kyle J. Norton
Fibrinolysis is the condition associated with the enzymatic breakdown of the fibrin in blood clots.
Where fibrin plays an essential role in hemostasis as the primary product of the coagulation cascade of fibrinolysis.
In other words, fibrinolysis is a process that prevents blood clots from growing to induce certain health problems such as cardiovascular disease.
Platelet aggregation is a condition characterized by platelets clumping together in the blood. The process also is necessary for the cover of vascular injury. However, overexpression of platelet counts in the blood is problematic to human health.
In other words, the production of blood platelets is to protect tissue injury against infection.
Furthermore, platelet disorders can lead to abnormal bleeding. The most common types of the genetic proposition of platelet disorders including
* Disorder of platelet adhesion, also known as Bernard-Soulier Syndrome is a condition in which the platelets fail to adhere together, leading to frequent bruises, nose bleeds, and bleeding in the mouth and gums.
* Disorder of platelet aggregation also known as Glanzmann Thrombasthenia is a condition that the platelets not only fail to cover at the site of an injury but also prolong the bleeding.
* Disorder of platelet secretion is a condition that causes the slowing down of normal platelet adhesion, aggregation, and repair of the blood vessel.
* Disorder of platelets procoagulant activity, also known as Scott Syndrome is a condition in which the platelets fail to promote activation of the blood clotting proteins.
Conventionally, certain medications with blood-thinning activity such as aspirin (ASA) and other drugs containing aspirin non-steroidal anti-inflammatory drugs, and some antibiotics may have a strong implication for the formation of platelets coagulation.
Dr. Wolberg AS in the examination of fibrinolysis in the changes in the local concentrations of pro- and anti-coagulants and cellular activities may affect the clot-forming wrote, "patterns of abnormal thrombin generation produce clots with altered fibrin structure and that these changes are associated with an increased risk of bleeding or thrombosis".
These results strongly outline the importance of fibrin in the formation of a blood clot in the presence of thrombin that converts fibrinogen to fibrin.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the treatment of fibrinolysis, researchers examined the influence of bromelain on platelet count, platelet aggregation, and platelet activity in vitro.
The study included blood samples taken from the antecubital vein of 10 healthy male non-smokers.
According to the tested observation, platelet count decreased after incubation with 2.5 and 5 mg bromelain/ml.
The levels of ADP and TRAP-6 associated with platelet aggregation were inhibited after incubation with 2.5 mg or 5 mg compared to control.
Interestingly, according to the flow cytometry, the percentage of the total number of platelets or unstimulated CD62P positive platelets.
In other words, under normal conditions, bromelain does not have any effect on unstimulated CD62P positive platelets even with higher incubation with 5 mg bromelain/ml compared to control.
However, after TRAP-6 stimulation with platelet aggregation, the incubation with 5 mg bromelain/ml led to a remarkable decrease, compared to the untreated control.
The changes of CD62P (TRAP-stimulated) and the results of platelet aggregation after incubation with bromelain in vitro may demonstrate the potential of bromelain as a substance for platelet inhibition.
Based on the findings, researchers said, "The changes of CD62P (TRAP-stimulated) and the results of platelet aggregation after incubation with bromelain in vitro may demonstrate the potential of bromelain as a substance for platelet inhibition".
These results suggested that bromelain has a strong effect on the prevention and treatment of cardiovascular disease associated with platelet aggregation.
Taken together, bromelain may be considered a remedy for the prevention and treatment of fibrinolysis,, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Properties and Therapeutic Application of Bromelain: A Review by Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar. (PMC)
(2) Thrombin generation and fibrin clot structure by Wolberg AS. (PubMed)
Fibrinolysis is the condition associated with the enzymatic breakdown of the fibrin in blood clots.
Where fibrin plays an essential role in hemostasis as the primary product of the coagulation cascade of fibrinolysis.
In other words, fibrinolysis is a process that prevents blood clots from growing to induce certain health problems such as cardiovascular disease.
Platelet aggregation is a condition characterized by platelets clumping together in the blood. The process also is necessary for the cover of vascular injury. However, overexpression of platelet counts in the blood is problematic to human health.
In other words, the production of blood platelets is to protect tissue injury against infection.
Furthermore, platelet disorders can lead to abnormal bleeding. The most common types of the genetic proposition of platelet disorders including
* Disorder of platelet adhesion, also known as Bernard-Soulier Syndrome is a condition in which the platelets fail to adhere together, leading to frequent bruises, nose bleeds, and bleeding in the mouth and gums.
* Disorder of platelet aggregation also known as Glanzmann Thrombasthenia is a condition that the platelets not only fail to cover at the site of an injury but also prolong the bleeding.
* Disorder of platelet secretion is a condition that causes the slowing down of normal platelet adhesion, aggregation, and repair of the blood vessel.
* Disorder of platelets procoagulant activity, also known as Scott Syndrome is a condition in which the platelets fail to promote activation of the blood clotting proteins.
Conventionally, certain medications with blood-thinning activity such as aspirin (ASA) and other drugs containing aspirin non-steroidal anti-inflammatory drugs, and some antibiotics may have a strong implication for the formation of platelets coagulation.
Dr. Wolberg AS in the examination of fibrinolysis in the changes in the local concentrations of pro- and anti-coagulants and cellular activities may affect the clot-forming wrote, "patterns of abnormal thrombin generation produce clots with altered fibrin structure and that these changes are associated with an increased risk of bleeding or thrombosis".
These results strongly outline the importance of fibrin in the formation of a blood clot in the presence of thrombin that converts fibrinogen to fibrin.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for the treatment of fibrinolysis, researchers examined the influence of bromelain on platelet count, platelet aggregation, and platelet activity in vitro.
The study included blood samples taken from the antecubital vein of 10 healthy male non-smokers.
According to the tested observation, platelet count decreased after incubation with 2.5 and 5 mg bromelain/ml.
The levels of ADP and TRAP-6 associated with platelet aggregation were inhibited after incubation with 2.5 mg or 5 mg compared to control.
Interestingly, according to the flow cytometry, the percentage of the total number of platelets or unstimulated CD62P positive platelets.
In other words, under normal conditions, bromelain does not have any effect on unstimulated CD62P positive platelets even with higher incubation with 5 mg bromelain/ml compared to control.
However, after TRAP-6 stimulation with platelet aggregation, the incubation with 5 mg bromelain/ml led to a remarkable decrease, compared to the untreated control.
The changes of CD62P (TRAP-stimulated) and the results of platelet aggregation after incubation with bromelain in vitro may demonstrate the potential of bromelain as a substance for platelet inhibition.
Based on the findings, researchers said, "The changes of CD62P (TRAP-stimulated) and the results of platelet aggregation after incubation with bromelain in vitro may demonstrate the potential of bromelain as a substance for platelet inhibition".
These results suggested that bromelain has a strong effect on the prevention and treatment of cardiovascular disease associated with platelet aggregation.
Taken together, bromelain may be considered a remedy for the prevention and treatment of fibrinolysis,, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Properties and Therapeutic Application of Bromelain: A Review by Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar. (PMC)
(2) Thrombin generation and fibrin clot structure by Wolberg AS. (PubMed)
#Healthy Veggie #Broccoli + Standard Triple Therapy Inhibit Cardio-Risk Parameters in Diabetes, Researchers Say
Kyle J. Norton
Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.
According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.
As of today, there is no cure for type 1 diabetes. Treatment focuses on managing blood sugar levels with insulin injection, diet, and lifestyle changes.
* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.
* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas's inability to produce enough insulin, because of the slow die-off of insulin-producing cells in the pancreas.
LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.
Therefore, LADA shares the same risk factors and symptoms similar to those of type 1 and 2 diabetes
* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.
Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding a potential plant that processes chronic diseases, researchers compared the effects of broccoli sprout powder, as an alternative and complementary treatment, to those of standard triple therapy, as a common medical treatment in cardiovascular diseases (CVD) risk in patients with type 2 diabetes.
The study included 86 type 2 diabetic patients with positive H.pylori stool antigen test (HpSAg) who were randomized to receive one of the three following regimens:
* STT) Standard triple therapy (omeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1000 mg, twice a day for 14 days),
* BSP) 6 g/d broccoli sprouts powder for 28 days, and
* Combination of these as STT + BSP. After 4 weeks of treatment.
Based on the results of the analysis of 77 participants who completed the study [STT (n = 28), BSP (n = 25), STT + BSP (n = 24)],
* Before treatment, the H.pylori eradication rates were 89.3%, 56.0%, and 91.7% in STT, BSP, and STT + BSP groups, respectively.
* After the treatment, both systolic and diastolic blood pressure significantly decreased in the STT + BSP group (P < 0.05).
* Serum triglycerides and TG/HDL-C ratio increased in the STT patients group (<0.05).
* Serum hs-CRP levels significantly decreased in the patients who were treated with BSP per se (3.0 ± 2.5 at baseline vs. 2.3 ± 2.1 after the treatment, P < 0.05).
Collectively, researchers said, "Compared to standard triple therapy, BSP regimen in addition to considerable effects on H.pylori eradication had also favorable properties on cardiovascular risk factors following the H.pylori eradication".
Taken together, broccoli may be considered a functional food for reducing the risk of CVD in diabetes, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes by Mirmiran P1, Bahadoran Z2, Golzarand M2, Zojaji H3, Azizi F. (PubMed)
Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.
According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.
As of today, there is no cure for type 1 diabetes. Treatment focuses on managing blood sugar levels with insulin injection, diet, and lifestyle changes.
* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.
* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas's inability to produce enough insulin, because of the slow die-off of insulin-producing cells in the pancreas.
LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.
Therefore, LADA shares the same risk factors and symptoms similar to those of type 1 and 2 diabetes
* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.
Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding a potential plant that processes chronic diseases, researchers compared the effects of broccoli sprout powder, as an alternative and complementary treatment, to those of standard triple therapy, as a common medical treatment in cardiovascular diseases (CVD) risk in patients with type 2 diabetes.
The study included 86 type 2 diabetic patients with positive H.pylori stool antigen test (HpSAg) who were randomized to receive one of the three following regimens:
* STT) Standard triple therapy (omeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1000 mg, twice a day for 14 days),
* BSP) 6 g/d broccoli sprouts powder for 28 days, and
* Combination of these as STT + BSP. After 4 weeks of treatment.
Based on the results of the analysis of 77 participants who completed the study [STT (n = 28), BSP (n = 25), STT + BSP (n = 24)],
* Before treatment, the H.pylori eradication rates were 89.3%, 56.0%, and 91.7% in STT, BSP, and STT + BSP groups, respectively.
* After the treatment, both systolic and diastolic blood pressure significantly decreased in the STT + BSP group (P < 0.05).
* Serum triglycerides and TG/HDL-C ratio increased in the STT patients group (<0.05).
* Serum hs-CRP levels significantly decreased in the patients who were treated with BSP per se (3.0 ± 2.5 at baseline vs. 2.3 ± 2.1 after the treatment, P < 0.05).
Collectively, researchers said, "Compared to standard triple therapy, BSP regimen in addition to considerable effects on H.pylori eradication had also favorable properties on cardiovascular risk factors following the H.pylori eradication".
Taken together, broccoli may be considered a functional food for reducing the risk of CVD in diabetes, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes by Mirmiran P1, Bahadoran Z2, Golzarand M2, Zojaji H3, Azizi F. (PubMed)
#Indicaxanthin Combined with Vitamin C Show an Efficacy in Restoring Redox Balance, Scientists Say
Kyle J. Norton
The redox status refers to the balance between the levels of free radicals and other reactive species and antioxidants.
Oxidants or ROS species can be produced by the body's cell metabolism or from external sources such as the air we breathe and the foods we eat.
Free radicals in moderate amounts are necessary for the body's functioning, inclduing NO for vascular relaxation.
Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction.
Antioxidants are stable molecules that play a critical role in protecting our body against oxidation.
There are 2 types of antioxidants, antioxidants produced by the host are called antioxidant enzymes and antioxidants come from dietary intake.
Under normal conditions, antioxidants produced by the host are good enough to keep the levels of free radicals in check.
Imbalanced levels of free radicals and antioxidants induced oxidative stress, a major cause of many chronic ailments. In other words, free radicals overexpression caused by chain oxidative reaction that induces oxidative stress causes protein, lipid, and DNA, leading to chronic diseases including cardiovascular disease, diabetes, and cancer.
According to Dr. Parvin Mirmiran, and colleagues in the joint study led by the Beheshti University of Medical Sciences, on oxidative stress in patients with metabolic syndrome, wrote, "(By) following a healthy pattern filled with fruits and vegetables ameliorates oxidative stress status and on the contrary, attachment to an unhealthy pattern, characterized by higher intakes of fast foods and processed foods, aggravated the oxidative stress levels in Tehranian individuals suffering from the metabolic syndrome".
Therefore, by enhancing antioxidant status in the body through regular physical activity and intake of fruits and vegetables which contain a high amount of dietary antioxidants to offset the free-radical toxic effects, the risk of oxidative stress can be reduced substantially.
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains found abundantly in beets, chard, etc.
In finding a potential compound that processes chemo-activity, researchers examined the effect of Indicaxanthin as a natural chemoactive and chemopreventive agent.
The randomized, double-blind, placebo-controlled, and crossover design included 8 women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm, and BMI of 21.69±0.66 kg/m2) randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml Placebo containing the same concentration of fruit juice ingredients except for Vitamin C and indicaxanthin.
According to the blood samples from women taken before and after the effort test without supplementation (baseline), pre-and post-test, 24 h and 48 h post-test with OFI or Placebo supplementation every day for 3 days before of effort test on a cycle ergometer and continued to take it for 2 consecutive days after testing, free radical H2O2 levels were significantly decreased and total antioxidant capacity (PAT) significantly increase in the OFI group comapred to placebo.
In other words, by comparing the effect on OFI and placebo groups, the antioxidants vitamin C and indicaxanthin may be the major constituents in the induction of the efficacy of OFI in restoring redox balance.
Based on the results, researchers said, " OFI supplementation might be used to restore redox balance after intense exercises in moderately trained women".
Taken together, indicaxanthin may be considered a remedy for restoring redox balance after intense exercises in moderately trained women, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women by Marianna Bellafiore, Anna Maria Pintaudi, Angelo Cataldo, Dario Cerasola, Alessandro Attanzio, Giuseppe Battaglia, Antonino Bianco, Antonio Palma. (Italian Journal of Anatomy and Embryology)
(2) Effect of dietary patterns on oxidative stress in patients with metabolic syndrome: Tehran Lipid and Glucose Study by Parvin Mirmiran, Ph.D. Hoda Hadavi, MSc, Azadeh Mottaghi, Ph.D., and Fereidoun Azizi, MD. (PMC)
The redox status refers to the balance between the levels of free radicals and other reactive species and antioxidants.
Oxidants or ROS species can be produced by the body's cell metabolism or from external sources such as the air we breathe and the foods we eat.
Free radicals in moderate amounts are necessary for the body's functioning, inclduing NO for vascular relaxation.
Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction.
Antioxidants are stable molecules that play a critical role in protecting our body against oxidation.
There are 2 types of antioxidants, antioxidants produced by the host are called antioxidant enzymes and antioxidants come from dietary intake.
Under normal conditions, antioxidants produced by the host are good enough to keep the levels of free radicals in check.
Imbalanced levels of free radicals and antioxidants induced oxidative stress, a major cause of many chronic ailments. In other words, free radicals overexpression caused by chain oxidative reaction that induces oxidative stress causes protein, lipid, and DNA, leading to chronic diseases including cardiovascular disease, diabetes, and cancer.
According to Dr. Parvin Mirmiran, and colleagues in the joint study led by the Beheshti University of Medical Sciences, on oxidative stress in patients with metabolic syndrome, wrote, "(By) following a healthy pattern filled with fruits and vegetables ameliorates oxidative stress status and on the contrary, attachment to an unhealthy pattern, characterized by higher intakes of fast foods and processed foods, aggravated the oxidative stress levels in Tehranian individuals suffering from the metabolic syndrome".
Therefore, by enhancing antioxidant status in the body through regular physical activity and intake of fruits and vegetables which contain a high amount of dietary antioxidants to offset the free-radical toxic effects, the risk of oxidative stress can be reduced substantially.
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains found abundantly in beets, chard, etc.
In finding a potential compound that processes chemo-activity, researchers examined the effect of Indicaxanthin as a natural chemoactive and chemopreventive agent.
The randomized, double-blind, placebo-controlled, and crossover design included 8 women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm, and BMI of 21.69±0.66 kg/m2) randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml Placebo containing the same concentration of fruit juice ingredients except for Vitamin C and indicaxanthin.
According to the blood samples from women taken before and after the effort test without supplementation (baseline), pre-and post-test, 24 h and 48 h post-test with OFI or Placebo supplementation every day for 3 days before of effort test on a cycle ergometer and continued to take it for 2 consecutive days after testing, free radical H2O2 levels were significantly decreased and total antioxidant capacity (PAT) significantly increase in the OFI group comapred to placebo.
In other words, by comparing the effect on OFI and placebo groups, the antioxidants vitamin C and indicaxanthin may be the major constituents in the induction of the efficacy of OFI in restoring redox balance.
Based on the results, researchers said, " OFI supplementation might be used to restore redox balance after intense exercises in moderately trained women".
Taken together, indicaxanthin may be considered a remedy for restoring redox balance after intense exercises in moderately trained women, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women by Marianna Bellafiore, Anna Maria Pintaudi, Angelo Cataldo, Dario Cerasola, Alessandro Attanzio, Giuseppe Battaglia, Antonino Bianco, Antonio Palma. (Italian Journal of Anatomy and Embryology)
(2) Effect of dietary patterns on oxidative stress in patients with metabolic syndrome: Tehran Lipid and Glucose Study by Parvin Mirmiran, Ph.D. Hoda Hadavi, MSc, Azadeh Mottaghi, Ph.D., and Fereidoun Azizi, MD. (PMC)
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