Kyle J. Norton
Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.
According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.
As of today, there is no cure for type 1 diabetes. Treatment focuses on managing blood sugar levels with insulin injection, diet, and lifestyle changes.
* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.
* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas's inability to produce enough insulin, because of the slow die-off of insulin-producing cells in the pancreas.
LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.
Therefore, LADA shares the same risk factors and symptoms similar to those of type 1 and 2 diabetes
* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.
Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding a potential plant that processes chronic diseases, researchers compared the effects of broccoli sprout powder, as an alternative and complementary treatment, to those of standard triple therapy, as a common medical treatment in cardiovascular diseases (CVD) risk in patients with type 2 diabetes.
The study included 86 type 2 diabetic patients with positive H.pylori stool antigen test (HpSAg) who were randomized to receive one of the three following regimens:
* STT) Standard triple therapy (omeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1000 mg, twice a day for 14 days),
* BSP) 6 g/d broccoli sprouts powder for 28 days, and
* Combination of these as STT + BSP. After 4 weeks of treatment.
Based on the results of the analysis of 77 participants who completed the study [STT (n = 28), BSP (n = 25), STT + BSP (n = 24)],
* Before treatment, the H.pylori eradication rates were 89.3%, 56.0%, and 91.7% in STT, BSP, and STT + BSP groups, respectively.
* After the treatment, both systolic and diastolic blood pressure significantly decreased in the STT + BSP group (P < 0.05).
* Serum triglycerides and TG/HDL-C ratio increased in the STT patients group (<0.05).
* Serum hs-CRP levels significantly decreased in the patients who were treated with BSP per se (3.0 ± 2.5 at baseline vs. 2.3 ± 2.1 after the treatment, P < 0.05).
Collectively, researchers said, "Compared to standard triple therapy, BSP regimen in addition to considerable effects on H.pylori eradication had also favorable properties on cardiovascular risk factors following the H.pylori eradication".
Taken together, broccoli may be considered a functional food for reducing the risk of CVD in diabetes, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes by Mirmiran P1, Bahadoran Z2, Golzarand M2, Zojaji H3, Azizi F. (PubMed)
Tuesday, 19 September 2023
#Indicaxanthin Combined with Vitamin C Show an Efficacy in Restoring Redox Balance, Scientists Say
Kyle J. Norton
The redox status refers to the balance between the levels of free radicals and other reactive species and antioxidants.
Oxidants or ROS species can be produced by the body's cell metabolism or from external sources such as the air we breathe and the foods we eat.
Free radicals in moderate amounts are necessary for the body's functioning, inclduing NO for vascular relaxation.
Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction.
Antioxidants are stable molecules that play a critical role in protecting our body against oxidation.
There are 2 types of antioxidants, antioxidants produced by the host are called antioxidant enzymes and antioxidants come from dietary intake.
Under normal conditions, antioxidants produced by the host are good enough to keep the levels of free radicals in check.
Imbalanced levels of free radicals and antioxidants induced oxidative stress, a major cause of many chronic ailments. In other words, free radicals overexpression caused by chain oxidative reaction that induces oxidative stress causes protein, lipid, and DNA, leading to chronic diseases including cardiovascular disease, diabetes, and cancer.
According to Dr. Parvin Mirmiran, and colleagues in the joint study led by the Beheshti University of Medical Sciences, on oxidative stress in patients with metabolic syndrome, wrote, "(By) following a healthy pattern filled with fruits and vegetables ameliorates oxidative stress status and on the contrary, attachment to an unhealthy pattern, characterized by higher intakes of fast foods and processed foods, aggravated the oxidative stress levels in Tehranian individuals suffering from the metabolic syndrome".
Therefore, by enhancing antioxidant status in the body through regular physical activity and intake of fruits and vegetables which contain a high amount of dietary antioxidants to offset the free-radical toxic effects, the risk of oxidative stress can be reduced substantially.
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains found abundantly in beets, chard, etc.
In finding a potential compound that processes chemo-activity, researchers examined the effect of Indicaxanthin as a natural chemoactive and chemopreventive agent.
The randomized, double-blind, placebo-controlled, and crossover design included 8 women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm, and BMI of 21.69±0.66 kg/m2) randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml Placebo containing the same concentration of fruit juice ingredients except for Vitamin C and indicaxanthin.
According to the blood samples from women taken before and after the effort test without supplementation (baseline), pre-and post-test, 24 h and 48 h post-test with OFI or Placebo supplementation every day for 3 days before of effort test on a cycle ergometer and continued to take it for 2 consecutive days after testing, free radical H2O2 levels were significantly decreased and total antioxidant capacity (PAT) significantly increase in the OFI group comapred to placebo.
In other words, by comparing the effect on OFI and placebo groups, the antioxidants vitamin C and indicaxanthin may be the major constituents in the induction of the efficacy of OFI in restoring redox balance.
Based on the results, researchers said, " OFI supplementation might be used to restore redox balance after intense exercises in moderately trained women".
Taken together, indicaxanthin may be considered a remedy for restoring redox balance after intense exercises in moderately trained women, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women by Marianna Bellafiore, Anna Maria Pintaudi, Angelo Cataldo, Dario Cerasola, Alessandro Attanzio, Giuseppe Battaglia, Antonino Bianco, Antonio Palma. (Italian Journal of Anatomy and Embryology)
(2) Effect of dietary patterns on oxidative stress in patients with metabolic syndrome: Tehran Lipid and Glucose Study by Parvin Mirmiran, Ph.D. Hoda Hadavi, MSc, Azadeh Mottaghi, Ph.D., and Fereidoun Azizi, MD. (PMC)
The redox status refers to the balance between the levels of free radicals and other reactive species and antioxidants.
Oxidants or ROS species can be produced by the body's cell metabolism or from external sources such as the air we breathe and the foods we eat.
Free radicals in moderate amounts are necessary for the body's functioning, inclduing NO for vascular relaxation.
Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction.
Antioxidants are stable molecules that play a critical role in protecting our body against oxidation.
There are 2 types of antioxidants, antioxidants produced by the host are called antioxidant enzymes and antioxidants come from dietary intake.
Under normal conditions, antioxidants produced by the host are good enough to keep the levels of free radicals in check.
Imbalanced levels of free radicals and antioxidants induced oxidative stress, a major cause of many chronic ailments. In other words, free radicals overexpression caused by chain oxidative reaction that induces oxidative stress causes protein, lipid, and DNA, leading to chronic diseases including cardiovascular disease, diabetes, and cancer.
According to Dr. Parvin Mirmiran, and colleagues in the joint study led by the Beheshti University of Medical Sciences, on oxidative stress in patients with metabolic syndrome, wrote, "(By) following a healthy pattern filled with fruits and vegetables ameliorates oxidative stress status and on the contrary, attachment to an unhealthy pattern, characterized by higher intakes of fast foods and processed foods, aggravated the oxidative stress levels in Tehranian individuals suffering from the metabolic syndrome".
Therefore, by enhancing antioxidant status in the body through regular physical activity and intake of fruits and vegetables which contain a high amount of dietary antioxidants to offset the free-radical toxic effects, the risk of oxidative stress can be reduced substantially.
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains found abundantly in beets, chard, etc.
In finding a potential compound that processes chemo-activity, researchers examined the effect of Indicaxanthin as a natural chemoactive and chemopreventive agent.
The randomized, double-blind, placebo-controlled, and crossover design included 8 women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm, and BMI of 21.69±0.66 kg/m2) randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml Placebo containing the same concentration of fruit juice ingredients except for Vitamin C and indicaxanthin.
According to the blood samples from women taken before and after the effort test without supplementation (baseline), pre-and post-test, 24 h and 48 h post-test with OFI or Placebo supplementation every day for 3 days before of effort test on a cycle ergometer and continued to take it for 2 consecutive days after testing, free radical H2O2 levels were significantly decreased and total antioxidant capacity (PAT) significantly increase in the OFI group comapred to placebo.
In other words, by comparing the effect on OFI and placebo groups, the antioxidants vitamin C and indicaxanthin may be the major constituents in the induction of the efficacy of OFI in restoring redox balance.
Based on the results, researchers said, " OFI supplementation might be used to restore redox balance after intense exercises in moderately trained women".
Taken together, indicaxanthin may be considered a remedy for restoring redox balance after intense exercises in moderately trained women, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women by Marianna Bellafiore, Anna Maria Pintaudi, Angelo Cataldo, Dario Cerasola, Alessandro Attanzio, Giuseppe Battaglia, Antonino Bianco, Antonio Palma. (Italian Journal of Anatomy and Embryology)
(2) Effect of dietary patterns on oxidative stress in patients with metabolic syndrome: Tehran Lipid and Glucose Study by Parvin Mirmiran, Ph.D. Hoda Hadavi, MSc, Azadeh Mottaghi, Ph.D., and Fereidoun Azizi, MD. (PMC)
#Herbal #Turmeric Inhibits the Risk of Chronic Inflammatory Diseases through Its Antioxidant Activity, Researchers Suggest
Kyle J. Norton
Inflammation is a process of the immune system that responds to harmful pathogens.
Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, and the largest white blood cells in the first line of defense stimulates the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.
However, in some cases, the overproduction of proinflammatory cytokines may damage nearby healthy cells and tissues, causing the formation of scars.
In severe cases, a protein with duo functions in the production of pro and anti-inflammatory cytokines which produce anti-inflammatory cytokines under normal conditions also switch to produce pro-inflammatory cytokines.
Most cases of acute inflammation are resolved within a few days without causing damage to the wound tissues.
However, if the immune first line of defense can not completely destroy the invaders within a period of 3 to 8 weeks, it will compromise, leading to low-grade chronic inflammation.
Diseases associated with low-grade chronic inflammation include diabetes, cardiovascular disease, and cancer.
Dr. in the examination of the etiology of chronic inflammation (CI) suggested that CI can result from the following:
* Failure to eliminate the agent causing an acute inflammation such as infectious disease-induced organisms
* Long-term exposure to a low level of particular irritant or foreign materials that cannot be eliminated by an enzymatic breakdown in the body including substances or industrial chemicals.
* An autoimmune disorder caused by the immune system that attacks healthy tissue, such as rheumatoid arthritis, systemic lupus erythematosus (SLE)
* Recurrent episodes of acute inflammation.
* Inflammation that causes oxidative stress and mitochondrial dysfunction such as advanced glycation end products (AGEs).
Conventionally, treatment of acute phase inflammation is to manage inflammation and prevent the risk of long-term damage, including anti-inflammatory nonsteroidal anti-inflammatory drugs (NSAIDs) which can be bought without a prescription.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound for the treatment of chronic diseases, researchers examined the efficacy of turmeric on continued oxidative stress and oxidative damage that lead to chronic inflammation in the mediation of most chronic diseases.
At the molecular level, turmeric showed significant anti-inflammatory activity by suppressing the proteins associated with the production of pro-inflammatory cytokines, including the NF-κB and COX-2.
Furthermore, the proteins associated with the response to cytokines and growth factors such as signal transducer and activator of transcription 3 were also inhibited by the injection of turmeric.
Moreover, the administration of turmeric also inhibited the production of ROS by promoting the production of antioxidant enzymes such as nrf2, a protein that regulates the expression of antioxidant proteins that protect against oxidative damage.
Furthermore, numerous studies also indicated that curcumin not only is highly potent against antimicrobial disease but also inhibits the onset of various chronic diseases including cancers, diabetes, obesity, cardiovascular, pulmonary, neurological, and autoimmune diseases.
As of today, over 100 different clinical trials also showed that curcumin is safe, tolerable and effective against various chronic diseases in humans.
Taken together, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of chronic inflammatory diseases pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases by Kunnumakkara AB1, Bordoloi D1, Padmavathi G1, Monisha J1, Roy NK1, Prasad S2, Aggarwal BB. (PubMed)
(2) Curcumin, inflammation, and chronic diseases: how are they linked? by He Y1, Yue Y2, Zheng X3,4, Zhang K5, Chen S6, Du Z. (PubMed)
(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)
Inflammation is a process of the immune system that responds to harmful pathogens.
Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, and the largest white blood cells in the first line of defense stimulates the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.
However, in some cases, the overproduction of proinflammatory cytokines may damage nearby healthy cells and tissues, causing the formation of scars.
In severe cases, a protein with duo functions in the production of pro and anti-inflammatory cytokines which produce anti-inflammatory cytokines under normal conditions also switch to produce pro-inflammatory cytokines.
Most cases of acute inflammation are resolved within a few days without causing damage to the wound tissues.
However, if the immune first line of defense can not completely destroy the invaders within a period of 3 to 8 weeks, it will compromise, leading to low-grade chronic inflammation.
Diseases associated with low-grade chronic inflammation include diabetes, cardiovascular disease, and cancer.
Dr. in the examination of the etiology of chronic inflammation (CI) suggested that CI can result from the following:
* Failure to eliminate the agent causing an acute inflammation such as infectious disease-induced organisms
* Long-term exposure to a low level of particular irritant or foreign materials that cannot be eliminated by an enzymatic breakdown in the body including substances or industrial chemicals.
* An autoimmune disorder caused by the immune system that attacks healthy tissue, such as rheumatoid arthritis, systemic lupus erythematosus (SLE)
* Recurrent episodes of acute inflammation.
* Inflammation that causes oxidative stress and mitochondrial dysfunction such as advanced glycation end products (AGEs).
Conventionally, treatment of acute phase inflammation is to manage inflammation and prevent the risk of long-term damage, including anti-inflammatory nonsteroidal anti-inflammatory drugs (NSAIDs) which can be bought without a prescription.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound for the treatment of chronic diseases, researchers examined the efficacy of turmeric on continued oxidative stress and oxidative damage that lead to chronic inflammation in the mediation of most chronic diseases.
At the molecular level, turmeric showed significant anti-inflammatory activity by suppressing the proteins associated with the production of pro-inflammatory cytokines, including the NF-κB and COX-2.
Furthermore, the proteins associated with the response to cytokines and growth factors such as signal transducer and activator of transcription 3 were also inhibited by the injection of turmeric.
Moreover, the administration of turmeric also inhibited the production of ROS by promoting the production of antioxidant enzymes such as nrf2, a protein that regulates the expression of antioxidant proteins that protect against oxidative damage.
Furthermore, numerous studies also indicated that curcumin not only is highly potent against antimicrobial disease but also inhibits the onset of various chronic diseases including cancers, diabetes, obesity, cardiovascular, pulmonary, neurological, and autoimmune diseases.
As of today, over 100 different clinical trials also showed that curcumin is safe, tolerable and effective against various chronic diseases in humans.
Taken together, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of chronic inflammatory diseases pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases by Kunnumakkara AB1, Bordoloi D1, Padmavathi G1, Monisha J1, Roy NK1, Prasad S2, Aggarwal BB. (PubMed)
(2) Curcumin, inflammation, and chronic diseases: how are they linked? by He Y1, Yue Y2, Zheng X3,4, Zhang K5, Chen S6, Du Z. (PubMed)
(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)
Xiao Wei Yan Powder (XWYP) Decoction Containing #Herbal #Dandelion Processes Anti #IntestinalMetaplasia and #AtypicalHyperplasia, Reserachers Say
Kyle J. Norton
The stomach located between the esophagus and the small intestine is a muscular, hollow, and important organ of the digestive tract.
The stomach plays a critical role in aiding the digestive system by secreting acid and enzymes that digest food induced by the stomach muscles that contract periodically, to churn the food and enhance digestion.
Atypical hyperplasia is a precancerous condition characterized by the accumulation of abnormal cells.
Intestinal metaplasia is a pre-gastric cancer condition caused by the change of cells in the stomach.
The exact causes of the condition are unknown. However, some researchers suggested that smoking and infection caused by H. pylori infection, genetic preposition, and environmental factors are some risk factors associated with the onset of intestinal metaplasia.
Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach lining in the beginning. At the advanced stage, the malignant cells can travel a distance away through blood and fluid circulation to infect other healthy tissues and organs.
Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.
Both atrophic gastritis and gastric cancer share the common symptoms of stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron deficiency anemia is found in the majority of patients with atrophic gastritis.
According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).
Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage has a 5 years survival rate of 67%.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belonging to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
In finding a natural ingredient for the prevention and treatment of gastric diseases, scientists examined the efficacy of Xiao Wei Yan Powder (XWYP) decoction on intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH).
XWYP is a traditional Chinese Medicine formula containing Smilax glabrate, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotundus, Bletilla striata, Glycyrrhiza uralensis, etc.
According to the results of 138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastric mucosa of chronic gastritis that was treated by Xiao Wei Yan Powder (XWYP) orally 5-7g, for a period from 2-4 months, compared to control, the decoction showed a significant effect rate of IM was 91.3% and that of the AH was 92.16% compared to the control group of 21.3% and 14.46% respectively.
More precisely, XWYP not only had marked therapeutic effects for IM and AH but also showed no toxic effects in the animal experiments revealed no toxic effect,
These results strongly suggested that a safety guarantee was provided for its clinical application.
Taken together, Dandelion in combination with other Chinese medicines may be considered a remedy for the treatment of intestinal metaplasia and atypical hyperplasia (AH), pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Treatment of intestinal metaplasia and atypical hyperplasia of gastric mucosa with xiao wei yan powder].[Article in Chinese] by Liu XR1, Han WQ, Sun DR. (PubMed)
The stomach located between the esophagus and the small intestine is a muscular, hollow, and important organ of the digestive tract.
The stomach plays a critical role in aiding the digestive system by secreting acid and enzymes that digest food induced by the stomach muscles that contract periodically, to churn the food and enhance digestion.
Atypical hyperplasia is a precancerous condition characterized by the accumulation of abnormal cells.
Intestinal metaplasia is a pre-gastric cancer condition caused by the change of cells in the stomach.
The exact causes of the condition are unknown. However, some researchers suggested that smoking and infection caused by H. pylori infection, genetic preposition, and environmental factors are some risk factors associated with the onset of intestinal metaplasia.
Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach lining in the beginning. At the advanced stage, the malignant cells can travel a distance away through blood and fluid circulation to infect other healthy tissues and organs.
Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.
Both atrophic gastritis and gastric cancer share the common symptoms of stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron deficiency anemia is found in the majority of patients with atrophic gastritis.
According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).
Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage has a 5 years survival rate of 67%.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belonging to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
In finding a natural ingredient for the prevention and treatment of gastric diseases, scientists examined the efficacy of Xiao Wei Yan Powder (XWYP) decoction on intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH).
XWYP is a traditional Chinese Medicine formula containing Smilax glabrate, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotundus, Bletilla striata, Glycyrrhiza uralensis, etc.
According to the results of 138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastric mucosa of chronic gastritis that was treated by Xiao Wei Yan Powder (XWYP) orally 5-7g, for a period from 2-4 months, compared to control, the decoction showed a significant effect rate of IM was 91.3% and that of the AH was 92.16% compared to the control group of 21.3% and 14.46% respectively.
More precisely, XWYP not only had marked therapeutic effects for IM and AH but also showed no toxic effects in the animal experiments revealed no toxic effect,
These results strongly suggested that a safety guarantee was provided for its clinical application.
Taken together, Dandelion in combination with other Chinese medicines may be considered a remedy for the treatment of intestinal metaplasia and atypical hyperplasia (AH), pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Treatment of intestinal metaplasia and atypical hyperplasia of gastric mucosa with xiao wei yan powder].[Article in Chinese] by Liu XR1, Han WQ, Sun DR. (PubMed)
#Pure #Allicin and Water #Extract of #Garlic Powder Inhibit the Proliferation of #EndometrialCancerCells, Researchers Find
Kyle J. Norton
Scientists may have found a natural ingredient for the prevention and treatment of endometrial cancer with no side effects, according to studies.
The endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particularly to the menstrual cycle.
Endometrial cancer is a late adulthood cancer characterized by the cell growth irregularly and uncontrollably in the endometrial tissue.
The cause of endometrial cancer is an alternation of call DNA in the endometrium.
Most cases of endometrial cancer start in the cells on the surface of the inner lining of the endometrium. After penetrating deeper into the organ tissue, the cancerous cell may induce secondary metastasis through lymph and blood.
Endometrial cancer is the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer. The average age diagnosed with endometrial cancer is 60.
According to the statistics provided by the American Cancer Society, every year, approximately,
63,000 new cases of cancer of the body of the uterus (uterine body or corpus) will be diagnosed.
Endometrial cancer causes the death of 11,350 women,, every year.
The 5-year survival rate for women with uterine cancer is 81%. However, the 5 years mortality rate in black women is substantially higher, compared to white women.
The most common risk factors of endometrial cancer are associated with hormone change due to menopause, use of birth control pills, and tamoxifen pregnancy, ovarian tumors, and polycystic ovarian syndrome.
Some researchers suggested that obesity is one major cause of hormone change associated with the onset of endometrial cancer.
Dt. Evan L. Busch, the lead scientists analyzed the endometrial cancer risk factors, said, " Compared with not being obese, obesity increased the odds of having an ER-positive tumor at cut points of 0% to 20% [maximum OR, 2.92; 95% confidence interval (CI), 1.34–6.33] as well as the odds of having a PR-positive tumor at cut points of 70% to 90% (maximum OR, 2.53; 95% CI, 1.36–4.68)".
And, " Obesity may be associated with greater endometrial tumor expression of ER and PR. Adding either marker does not appear to improve mortality prediction beyond the standard predictors".
Allicin is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
With an aim to find the ingredients for the treatment of endometrial cancer, researchers determined whether pure allicin exhibits the antiproliferative effect reported for garlic in vitro models.
Treatment of allicin, but not its precursor alliin, inhibited the proliferation of human endometrial (Ishikawa) cancer cells (50% inhibitory concentration = 10-25 microM).
Furthermore, the pure allicin and water extract of garlic powder with equivalent allicin concentrations displayed a similar potency.
The result strongly suggested that allicin is responsible for the antiproliferative effect of the extract.
Allicin treatments inhibited the levels of antioxidants produced by the cancer cell line and the extent of the decrease in glutathione (GSH) levels correlated well (r = 0.75) with the growth-inhibitory activity of allicin.
However, the magnitude and kinetics of which significantly varied depending on the cancer cell type.
Dr. Hirsch K, the lead scientist said, allicin plays a major role in the antiproliferative effect of water-soluble garlic preparations and that this effect may be attributed to the ability of allicin to transiently deplete the intracellular GSH level.
Moreover, the treatment of allicin also induces cancer cell death through activating proteins associated with cell apoptosis and cell death programming.
, the efficacy of allicin also was attributed to the function of bioactive compounds stimulating the protein involved "on" or "off" switch of cell apoptosis, as well as inhibiting the antioxidant enzymes produced by the cancer cells.
Taken together, phytochemical allicin may be considered a bioactive compound for reducing risk and combined with the primary medicine for the treatment of endometrial cancer.
However, intake of allicin in the form of a supplement should be taken with extreme care as acute toxicity was reported in a number of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation by Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. (PubMed)
(2) Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway by Cha JH, Choi YJ, Cha SH, Choi CH, Cho WH. (PubMed)
(3) Endometrial Cancer Risk Factors, Hormone Receptors, and Mortality Prediction by Evan L. Busch, Marta Crous-Bou, Jennifer Prescott, Maxine M. Chen, Michael J. Downing, Bernard A. Rosner, George L. Mutter and Immaculata De Vivo. (AACR)
Scientists may have found a natural ingredient for the prevention and treatment of endometrial cancer with no side effects, according to studies.
The endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particularly to the menstrual cycle.
Endometrial cancer is a late adulthood cancer characterized by the cell growth irregularly and uncontrollably in the endometrial tissue.
The cause of endometrial cancer is an alternation of call DNA in the endometrium.
Most cases of endometrial cancer start in the cells on the surface of the inner lining of the endometrium. After penetrating deeper into the organ tissue, the cancerous cell may induce secondary metastasis through lymph and blood.
Endometrial cancer is the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer. The average age diagnosed with endometrial cancer is 60.
According to the statistics provided by the American Cancer Society, every year, approximately,
63,000 new cases of cancer of the body of the uterus (uterine body or corpus) will be diagnosed.
Endometrial cancer causes the death of 11,350 women,, every year.
The 5-year survival rate for women with uterine cancer is 81%. However, the 5 years mortality rate in black women is substantially higher, compared to white women.
The most common risk factors of endometrial cancer are associated with hormone change due to menopause, use of birth control pills, and tamoxifen pregnancy, ovarian tumors, and polycystic ovarian syndrome.
Some researchers suggested that obesity is one major cause of hormone change associated with the onset of endometrial cancer.
Dt. Evan L. Busch, the lead scientists analyzed the endometrial cancer risk factors, said, " Compared with not being obese, obesity increased the odds of having an ER-positive tumor at cut points of 0% to 20% [maximum OR, 2.92; 95% confidence interval (CI), 1.34–6.33] as well as the odds of having a PR-positive tumor at cut points of 70% to 90% (maximum OR, 2.53; 95% CI, 1.36–4.68)".
And, " Obesity may be associated with greater endometrial tumor expression of ER and PR. Adding either marker does not appear to improve mortality prediction beyond the standard predictors".
Allicin is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
With an aim to find the ingredients for the treatment of endometrial cancer, researchers determined whether pure allicin exhibits the antiproliferative effect reported for garlic in vitro models.
Treatment of allicin, but not its precursor alliin, inhibited the proliferation of human endometrial (Ishikawa) cancer cells (50% inhibitory concentration = 10-25 microM).
Furthermore, the pure allicin and water extract of garlic powder with equivalent allicin concentrations displayed a similar potency.
The result strongly suggested that allicin is responsible for the antiproliferative effect of the extract.
Allicin treatments inhibited the levels of antioxidants produced by the cancer cell line and the extent of the decrease in glutathione (GSH) levels correlated well (r = 0.75) with the growth-inhibitory activity of allicin.
However, the magnitude and kinetics of which significantly varied depending on the cancer cell type.
Dr. Hirsch K, the lead scientist said, allicin plays a major role in the antiproliferative effect of water-soluble garlic preparations and that this effect may be attributed to the ability of allicin to transiently deplete the intracellular GSH level.
Moreover, the treatment of allicin also induces cancer cell death through activating proteins associated with cell apoptosis and cell death programming.
, the efficacy of allicin also was attributed to the function of bioactive compounds stimulating the protein involved "on" or "off" switch of cell apoptosis, as well as inhibiting the antioxidant enzymes produced by the cancer cells.
Taken together, phytochemical allicin may be considered a bioactive compound for reducing risk and combined with the primary medicine for the treatment of endometrial cancer.
However, intake of allicin in the form of a supplement should be taken with extreme care as acute toxicity was reported in a number of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation by Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. (PubMed)
(2) Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway by Cha JH, Choi YJ, Cha SH, Choi CH, Cho WH. (PubMed)
(3) Endometrial Cancer Risk Factors, Hormone Receptors, and Mortality Prediction by Evan L. Busch, Marta Crous-Bou, Jennifer Prescott, Maxine M. Chen, Michael J. Downing, Bernard A. Rosner, George L. Mutter and Immaculata De Vivo. (AACR)
#Herbal #Ashwagandha Porcesses Anti Inflammatory Effects Agaisnt #RheumatoidArthritis RA, Researchers Find
Kyle J. Norton
Rheumatoid Arthritis, a type of musculoskeletal disorder (MSD) is a chronic disorder characterized by inflammation of the flexible (synovial) joints tissues, and organs in the body.
The disease affects more women than men and generally occurs after the age of 50, causing the diminished quality of life of many elders.
Musculoskeletal disorders (MSDs) are medical conditions mostly caused by work-related occupations and working environments, affecting patients’ muscles, joints, tendons, ligaments, and nerves and developing over time.
According to a community sample of 73 females and 32 males aged 85 and over who underwent a standardized examination at home, musculoskeletal pain was reported by 57% of those interviewed.
According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affect over 52 million adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.
Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.
A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.
Patient with rheumatoid arthritis (RA) often associates with valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot. The kinematic and kinetic gait changes in rheumatoid arthritis (RA) are the result of a significant reduction in joint motions, and joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...
Long-term bone damage and the prolonged onset of the disease can induce deformities of the hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.
The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations that can affect daily living and quality of life.
Furthermore, rheumatoid nodules, lumps on the skin, closed to the joint have been found to affect the joints of patients with RA.
Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in the early stage of rheumatoid arthritis.
Dr. Motl RW and Dr. McAuley E. in the assessment of chronic diseases said, " The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) are embedded in the "Graying of America""(29), including patients with RA.
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In finding a potent compound for the treatment of arthritis, researchers examined the effect of Cannabis sativa, Prunella vulgaris, and Withania somnifera) possess anti-inflammatory, rheumatic arthritis properties.
According to the tested analysis, the tested medical plants showed a significant effect on RA by targeting TNF-α through its anti-inflammatory activity.
More precisely, twenty unique molecules found in the medical plants including Withania somnifera were attributed to the utmost binding affinity and least binding energies associated with the interaction of receptor-ligand interactions of residues against RA.
Based on the findings, researchers said, "The RA patients should use reported compounds for the prescription of RA by targeting TNF-α. This report is opening new dimensions for designing innovative therapeutic targets to cure RA.".
Taken together, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of RA, pending the result of a larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withaniasomnifera compounds elucidating the medicinal properties against rheumatoid arthritis by Zaka M1, Sehgal SA2, Shafique S3, Abbasi BH. (PubMed)
(2) Most Common Diseases of elder: The Clinical Trials and Studies of musculoskeletal disorders: Osteoporosis - The Symptoms by Kyle J. Norton
(3) Physical activity, disability, and quality of life in older adults by Motl RW1, McAuley E. (PubMed)
Rheumatoid Arthritis, a type of musculoskeletal disorder (MSD) is a chronic disorder characterized by inflammation of the flexible (synovial) joints tissues, and organs in the body.
The disease affects more women than men and generally occurs after the age of 50, causing the diminished quality of life of many elders.
Musculoskeletal disorders (MSDs) are medical conditions mostly caused by work-related occupations and working environments, affecting patients’ muscles, joints, tendons, ligaments, and nerves and developing over time.
According to a community sample of 73 females and 32 males aged 85 and over who underwent a standardized examination at home, musculoskeletal pain was reported by 57% of those interviewed.
According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affect over 52 million adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.
Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.
A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.
Patient with rheumatoid arthritis (RA) often associates with valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot. The kinematic and kinetic gait changes in rheumatoid arthritis (RA) are the result of a significant reduction in joint motions, and joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...
Long-term bone damage and the prolonged onset of the disease can induce deformities of the hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.
The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations that can affect daily living and quality of life.
Furthermore, rheumatoid nodules, lumps on the skin, closed to the joint have been found to affect the joints of patients with RA.
Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in the early stage of rheumatoid arthritis.
Dr. Motl RW and Dr. McAuley E. in the assessment of chronic diseases said, " The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) are embedded in the "Graying of America""(29), including patients with RA.
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In finding a potent compound for the treatment of arthritis, researchers examined the effect of Cannabis sativa, Prunella vulgaris, and Withania somnifera) possess anti-inflammatory, rheumatic arthritis properties.
According to the tested analysis, the tested medical plants showed a significant effect on RA by targeting TNF-α through its anti-inflammatory activity.
More precisely, twenty unique molecules found in the medical plants including Withania somnifera were attributed to the utmost binding affinity and least binding energies associated with the interaction of receptor-ligand interactions of residues against RA.
Based on the findings, researchers said, "The RA patients should use reported compounds for the prescription of RA by targeting TNF-α. This report is opening new dimensions for designing innovative therapeutic targets to cure RA.".
Taken together, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of RA, pending the result of a larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withaniasomnifera compounds elucidating the medicinal properties against rheumatoid arthritis by Zaka M1, Sehgal SA2, Shafique S3, Abbasi BH. (PubMed)
(2) Most Common Diseases of elder: The Clinical Trials and Studies of musculoskeletal disorders: Osteoporosis - The Symptoms by Kyle J. Norton
(3) Physical activity, disability, and quality of life in older adults by Motl RW1, McAuley E. (PubMed)
#Phytochemical #Betanin and #Isobetanin, the Powerful Antioxidants In Beetroot Inhibit Diseases Associated with Oxidative Stress
Kyle J. Norton
Antioxidants are stable molecules that inhibit the onset of oxidation caused by free radicals.
Free radicals, on the other hand, are unstable molecules that cause oxidation, with unpaired electrons in the outermost ring.
Free radical scavengers are types of antioxidants that play a critical role in neutralizing free radicals before they can induce a chain reaction which can not be stopped until all unpaired electrons in the outermost are paired.
Overexpression of free radicals or depletion of antioxidant enzymes in the host body can lead to
oxidative stress, an indicator associated with the unbalanced ratio of the levels of antioxidants/free radicals
Epidemiologically, the imbalance ratio of free radicals/antioxidants has been linked to the onset of many chronic diseases, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke due to cellular, lipid and protein damage.
However, free radicals have the potential to be extremely harmful contaminants and extremely helpful for the treatment of cancers through their cytotoxic activity because of their high reactivity,
Believe it or not, free radicals present in the body in a moderate amount are important to the body's cardio-functioning, including the promotion of vascular function.
Some researchers in the examination of the effect of antioxidant-rich foods in the risk-free radicals initiation suggested that diet rich in fruits and vegetables and less in meat and process foods have a lower risk of oxidative stress and oxidative stress-related diseases.
The National Centre for Complementary and Integrative Health in the article "Antioxidants: In-Depth" wrote, "Several decades of dietary research findings suggested that consuming greater amounts of antioxidant-rich foods might help to protect against diseases. Because of these results, there has been a lot of research on antioxidant supplements".
And "Observational studies on the typical eating habits, lifestyles, and health histories of large groups of people have shown that those who ate more vegetables and fruits had lower risks of several diseases, including cardiovascular disease, stroke, cancer, and cataracts".
Isobetanin is Phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains, found abundantly in beets, chard,...
In finding a potent ingredient for the treatment of diseases associated with oxidative stress, researchers examined the chemical constituents of betacyanin of Djulis (Chenopodium fromosanum), a native cereal plant in Taiwan.
Betacyanin of Djulis exhibited a significant antioxidant capacity at the maximum absorbance at 530 nm, depending on the pH.
Major chemical compounds that exerted a significant antioxidant capacity are betanin (47.8%), isobetanin (30.0%) with m/z 551.0, and armaranthin (13.6%), isoamaranthinee (8.6%).
According to the purified form, the pigment extract by HPLC, Betanin, and Isobetanin totally accounted for more than 70% of FRAP(ferric-reducing antioxidant power) which plays an important role in this regard of absorptivity for a variety of antioxidants and free radical scavenging capacity.
These results strongly suggested that betanin and isobetanin antioxidants process a strong antioxidant activity that may provide a basis for its sustainable utilization in the food industry.
Taken altogether, isobetanin may be considered a remedy for the prevention and treatment of diseases associated with oxidative stress pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Thermal and pH stability of betacyanin pigment of Djulis (Chenopodium formosanum) in Taiwan and their relation to antioxidant activity" by Tsai PJ, Sheu CH, Wu PH, Sun YF.(PubMed)
Antioxidants are stable molecules that inhibit the onset of oxidation caused by free radicals.
Free radicals, on the other hand, are unstable molecules that cause oxidation, with unpaired electrons in the outermost ring.
Free radical scavengers are types of antioxidants that play a critical role in neutralizing free radicals before they can induce a chain reaction which can not be stopped until all unpaired electrons in the outermost are paired.
Overexpression of free radicals or depletion of antioxidant enzymes in the host body can lead to
oxidative stress, an indicator associated with the unbalanced ratio of the levels of antioxidants/free radicals
Epidemiologically, the imbalance ratio of free radicals/antioxidants has been linked to the onset of many chronic diseases, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke due to cellular, lipid and protein damage.
However, free radicals have the potential to be extremely harmful contaminants and extremely helpful for the treatment of cancers through their cytotoxic activity because of their high reactivity,
Believe it or not, free radicals present in the body in a moderate amount are important to the body's cardio-functioning, including the promotion of vascular function.
Some researchers in the examination of the effect of antioxidant-rich foods in the risk-free radicals initiation suggested that diet rich in fruits and vegetables and less in meat and process foods have a lower risk of oxidative stress and oxidative stress-related diseases.
The National Centre for Complementary and Integrative Health in the article "Antioxidants: In-Depth" wrote, "Several decades of dietary research findings suggested that consuming greater amounts of antioxidant-rich foods might help to protect against diseases. Because of these results, there has been a lot of research on antioxidant supplements".
And "Observational studies on the typical eating habits, lifestyles, and health histories of large groups of people have shown that those who ate more vegetables and fruits had lower risks of several diseases, including cardiovascular disease, stroke, cancer, and cataracts".
Isobetanin is Phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains, found abundantly in beets, chard,...
In finding a potent ingredient for the treatment of diseases associated with oxidative stress, researchers examined the chemical constituents of betacyanin of Djulis (Chenopodium fromosanum), a native cereal plant in Taiwan.
Betacyanin of Djulis exhibited a significant antioxidant capacity at the maximum absorbance at 530 nm, depending on the pH.
Major chemical compounds that exerted a significant antioxidant capacity are betanin (47.8%), isobetanin (30.0%) with m/z 551.0, and armaranthin (13.6%), isoamaranthinee (8.6%).
According to the purified form, the pigment extract by HPLC, Betanin, and Isobetanin totally accounted for more than 70% of FRAP(ferric-reducing antioxidant power) which plays an important role in this regard of absorptivity for a variety of antioxidants and free radical scavenging capacity.
These results strongly suggested that betanin and isobetanin antioxidants process a strong antioxidant activity that may provide a basis for its sustainable utilization in the food industry.
Taken altogether, isobetanin may be considered a remedy for the prevention and treatment of diseases associated with oxidative stress pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
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Holistic System In Existence That Will Show You How To
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Thermal and pH stability of betacyanin pigment of Djulis (Chenopodium formosanum) in Taiwan and their relation to antioxidant activity" by Tsai PJ, Sheu CH, Wu PH, Sun YF.(PubMed)
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