Wednesday, 13 September 2023

#TualangHoney Supplementation Shows a Strong Effect in Boosting Memory by Inhibiting #Oxidativestress Markers, Researchers Say

Kyle J. Norton

Honey may have a profound and positive effect on boosting human memory, some scientists suggested
Memory is a process of the mind in learning and storing information.

Memory impairment is a condition of not remembering new and current events which may be recalled in a short period of time, affecting mostly the older population.

Memory impairment is an early symptom associated with late-life neurodegenerative diseases.

In contrast to general belief, memory impairment not only is associated with the progression of neurodegenerative diseases but also can be caused by other factors such as medical conditions including stroke and brain injury.

Long-term use of certain medications such as antidepressants, antihistamines, anti-anxiety medications, excessive alcohol drinking, substance abuse, and tobacco are some major risk factors associated with the onset of memory loss.

Some researchers suggested that people who are living under long-term stress and anxiety or follow a nutritionally deficient diet are most vulnerable to the condition.

According to the article "Stress might lead to memory loss and brain shrinkage, study says" By Sandee LaMotte, CNN wrote, "If you live a high-stress life, you could have memory loss and brain shrinkage before you turn 50, according to a study published Wednesday in the journal Neurology".

"Higher levels of cortisol, a stress hormone, seem to predict brain function, brain size, and performance on cognitive tests," said study author Dr. Sudha Seshadri, professor of neurology at UT Health San Antonio.

"We found memory loss and brain shrinkage in relatively young people long before any symptoms could be seen," Seshadri said. "It's never too early to be mindful of reducing stress."

In other words, long-term stress can induce the production of certain hormones such as cortisol which have strong implications on the brain in the induction of memory loss.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.

In finding the correlation and association between aging and stress exposure and memory impairment, researchers examined the potential protective effects of Tualang honey supplementation on memory performance in aged rats exposed to noise stress.

Tested rats were given orally, 200 mg/kg body weight of Tualang honey supplementation for 28 days, before exposing to loud noise, 100 dB(A), 4 hours daily for 14 days.

Rats subjected to noise stress exhibited significantly lower memory performance and higher oxidative stress, through the increased expression of oxidative stress markers, elevated malondialdehyde, and protein carbonyl levels.

The stress rats also exhibited a reduction in the levels of antioxidant enzymes compared to the nonstressed rats.

Tualang honey supplementation applied to the stress rats showed a significant improvement in memory performance, by decreasing oxidative stress levels and increasing the brain-derived neurotrophic factor (BDNF) concentration, which was reduced due to stress.

Furthermore, Tualang honey also normalized the ratio of free radicals and antioxidants in the stress rat's body and enhanced neuronal proliferation in the medial prefrontal cortex (mPFC) and hippocampus associated with memory, particularly, in long-term memory.

Dr. Azman KF, the lead scientist in the final report wrote, "Tualang honey protects against memory decline due to stress exposure and/or aging via enhancement of mPFC and hippocampal morphology possibly secondary to a reduction in brain oxidative stress and/or upregulation of BDNF concentration and cholinergic system".

The results underlined the effects of Tualang honey effect in boosting short and long-term memory which was significantly reduced by stress exposure and/or aging.

Moreover, in the study of a total of forty-eight adult male rats randomly divided into the following four groups: i) nonstressed with a vehicle, ii) nonstressed with Tualang honey, iii) stressed with a vehicle, and iv) stressed with honey with supplement was given once daily via oral gavage at 0.2 g/kg body weight, researchers found that
* The rats subjected to noise stress were found to process higher levels of depressive-like behavior and lower memory functions compared to the unexposed control rats.

* Tuatang honey supplementation regimen successfully counteracted the effects of noise stress.

* Tualng honey also increased the climbing swimming and mobility times significantly.

These results suggested that Tualang honey normalizes the cognitive function of the rats exposed to noise stress, similar to those of the first study.

Taken together, Tualang honey may be considered a functional food for the prevention and combined with the primary therapy for the treatment of cognitive impairment, pending the larger and multicenter human study.


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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Tualang Honey Attenuates Noise Stress-Induced Memory Deficits in Aged Rats by Azman KF1, Zakaria R1, Abdul Aziz CB1, Othman Z2. (PubMed)
(2) Tualang honey improves memory performance and decreases depressive-like behavior in rats exposed to loud noise stress by Azman KF1, Zakaria R, AbdAziz C, Othman Z, Al-Rahbi B. (PubMed)
(3) Potential Role of Honey in Learning and Memory by Othman Z1, Zakaria R2, Hussain NHN3, Hassan A4, Shafin N5, Al-Rahbi B6, Ahmad AH. (PubMed)

#SauredyOil (3.5 g of LCMUFA and 3.4 g of Omega-3 FAs) Supplementation Processes a Positive Effect on Plasma Cholesterols in Healthy Individuals

Kyle J. Norton

Lipid refers to cholesterol and triglycerides.
Hypertriglyceridemia is a health issue associated with abnormally high blood levels of triglycerides,
Triglycerides are body fats found in humans derived from glycerol and saturated, monounsaturated, and polyunsaturated fatty acids.

The triglycerides are stored in your fat cells for energy in the future when the body needs them.
if the levels of triglycerides are above 500 mg/dL (above 5.7 mmol/L), you have high blood triglyceride.

Abnormal high levels of triglycerides have been found to induce symptoms of gastrointestinal pain. difficulty breathing, memory loss, dementia, and yellowish deposits of fat on or around the eyelids.

Hyperlipidemia is a medical condition of abnormally high levels of cholesterol and fat in the bloodstream.

High blood cholesterol is the most common cause of hyperlipidemia. According to statistics provided by the CDC, more than 12% of adults age 20 and older are living with high blood cholesterol with a total cholesterol higher than 240 mg/dL. and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

In other words, hyperlipidemia has a high prevalence ratio that affects over 100 million Americans and the condition is increasing at an alarming rate due to overweight and obesity.

Believe it or not, only half of the people with high blood cholesterol benefit from taking the lowering blood cholesterol medicine.

Cholesterol is produced by the liver and absorbed through diet to build cell walls, produce steroid hormone and vitamin D, and aid digestive, The primary of triglycerides function is to store unused calories and provide your body with energy.


The healthy ratio of low-density lipoprotein (LDL)/high-density lipoprotein (HDL) is a number that is less than 4.

Fish oil is derived from the tissues of fish, containing a high amount of omega-3 fatty acids.
The three main components of omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

In finding a potential phytochemical for the treatment of chronic disease, researchers launched a first-in-human trial of LCMUFA-rich saury fish oil supplementation effect on plasma lipids.

The double-blind, randomized, crossover clinical trial included 30 healthy normolipidemic adults (BMI <25 kg/m2; mean TG, 84 mg/dL) who were treated with either 12 g of Sauredy oil (3.5 g of LCMUFA and 3.4 g of omega-3 FAs) or identical capsules with control oil (a mixture of sardine and olive oil; 4.9 g of shorter-chain MUFA oleate and 3 g of omega-3 FAs).

According to the results, saury oil supplementation was safe and resulted in LDL particle counts 12% lower than control oil.

In a linear mixed effect model, saury oil also showed a minor effect on increasing HDL particle size (9.8 nm vs 9.7 nm; P < .05), compared to the control oil which increased LDL-C by only 7.5% compared with baseline.

Most importantly, saury oil exerted similar effects compared to control oil on lowering plasma TG levels, VLDL, and TG-rich lipoprotein particle counts (by ∼16%, 25%, and 35%, respectively; P < .05), and increasing HDL-C and cholesterol efflux capacity (by ∼6% and 8%, respectively; P < .05) compared with baseline.


Based on the findings, researchers said, "Saury oil supplementation is well tolerated and has beneficial effects on several cardiovascular parameters, such as LDL particle counts, HDL particle size, and plasma TG levels".

Taken altogether, fish oil may be considered a functional food for the protection of cardiovascular parameters, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Supplementation with saury oil, a fish oil high in omega-11 monounsaturated fatty acids, improves plasma lipids in healthy subjects by Yang ZH1, Amar M2, Sorokin AV2, Troendle J3, Courville AB4, Sampson M5, Playford MP6, Yang S4, Stagliano M2, Ling C5, Donkor K2, Shamburek RD2, Mehta NN6, Remaley AT. (PubMed)

hypertriglyceridemia
(1) Recent developments in pharmacotherapy for hypertriglyceridemia: what's the current state of the art? by Florentin M1, Kostapanos MS2, Anagnostis P3, Liamis G. (PubMed)

#Honey Normalizes Basal Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), and Heart Rate (HR), According to Human Studies

Kyle J. Norton

Scientists may have found a natural alternative for the treatment of hypertension, according to studies.
Hypertension is a condition of abnormally high blood pressure. It is a member of the cluster conditions associated with an increased risk of heart disease and stroke.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.

Bad eating habits, unhealthy lifestyle and certain medical conditions such as kidney disease, diabetes, and sleep apnea are some of the risk factors of high blood pressure.

However, some researchers suggested that the prevalence of obesity over the past few decades may have a strong impact on the increased high blood pressure risk in the US.


Dr. Shu-Zhong Jiang and colleagues in examining obesity and the high blood pressure risk wrote, "Obesity is a major risk for essential hypertension, diabetes and another morbidity that contribute to the development of kidney disease because it mainly increases tubular reabsorption to impair pressure natriuresis and cause volume expansion,...".

, "Additionally, obesity causes cardiovascular and renal diseases through several mechanisms including hypertension, hyperglycemia, inflammation, dyslipidemia, and atherosclerosis, which are disorders that can coexist, particularly in the presence of excess visceral fat to cause metabolic syndrome (65) and are characterized by alteration in fat metabolism through lipid accumulation".

The results strongly suggested that obesity not only is associated with hypertension but also is a major contributor to the risk of other chronic diseases.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.

Researchers on finding a herbal remedy for the treatment of hypertension with no side effects examined the honey effect on blood pressure and heart rate.

The study included 50 healthy male subjects, who were given 20 ml of honey to consume, and their systolic SBP, DBP, and HR were measured at different intervals; 15 minutes, 30 minutes, and 60 minutes after the intake of honey.

Honey treatment significantly (p = 0.05) decreased SBP from 117.80±0.88 to 110.20±2.14 after 15 minutes of honey intake.

The blood pressure of the honey treatment was maintained as the reading after 30 minutes of honey consumption was 111.33±2.14, and 60 minutes of honey intake was 110.4±2.08.

The findings clearly suggested that honey has a short-term effect in reducing blood pressure in healthy individuals.

In order to reveal more information about honey anti-high blood pressure activity, researchers investigated the honey effect on blood pressure and heart rate in healthy males and females.


The study included 100 healthy male and female participants who were given 20ml honey orally administered. The basal systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) before injection of honey were taken as the control values.

Diastolic blood pressure and heart rate were measured at 15, 30, and 60 minutes with a digital sphygmomanometer and analog sphygmomanometer as a check.

The results showed that mean SBP decreased significantly in female compared to male at control, after 15, 30 and 60 minutes of oral administration of 20ml of honey.


DBP decreased significantly in female compared to male at control, after 15 minutes and 60 minutes of oral administration of 20ml of honey and HR decreased (p=.05) significantly.

The results indicated that honey has a strong effect in reducing blood pressure in females compared to the male counterpart, probably due to hormone expression.

Taken together, honey may be considered a functioning remedy for the prevention and treatment of high blood pressure, particularly in females, pending the confirmation of a large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1)Honey’s Ability to Reduce Blood Pressure and Heart Rate in Healthy Male Subjects by Esther Oluwasola Aluko, Nigeria Titilope Helen Olubobokun, Dara Ezekiel Atang. (Research Gate)
(2) Comparative Study of Effect of Honey on Blood Pressure and Heart Rate in Healthy Male and Female Subjects Aluko Esther Olusola1*, Olubobokun Titilope Helen1, I. Bassey Enobong2 and Atang Dara Ezekiel. (British Journal of Medicine & Medical Research)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)

#Healthyfood #Onion's #Quercetin Polyuronide Contents Process Anti-Atherogenic Property Associated with A Reduced Risk of CardiovascularDisease, Researchers Say

Kyle J. Norton

Atherosclerosis is a condition characterized by the accumulated plaque on the arterial wall. Over time the condition can cause stiffening and hardening of the arteries, leading to cardiovascular disease.
Anti-atherogenic activity is the process of preventing or inhibiting atherogenesis associated with the reduced formation of fatty plaques in the arteries.

In other words, anything, including the use of substances such as herbal remedy that prevents the blockage or narrowing of the arteries is considered atheroprotective effects.

Plaque in the arteries is formed by substances including fat, cholesterol, calcium, and other substances found in the blood in the bloodstream. However, most cases of atherosclerosis are also involved in the amount of cholesterol that normally returns to the liver in healthy individuals remaining in the blood due to low levels of good cholesterol (HDL) or overexpression of bad cholesterol (LDL).

In other words, an unhealthy ratio of low and high-density lipoprotein is also one of the major risk factors for atherosclerosis.

The healthy ratio of blood cholesterol is any number that is less than 4 (LDL)/ 1 (HDL).

Some researchers suggested by increasing the levels of good cholesterol in the blood, the risk of atherosclerosis can be reduced.

Dr. Feig JE and colleagues wrote, "Pharmacologic agents, such as fibrates and niacin that increase HDL cholesterol levels have been associated with decreased cardiovascular events and beneficial effects on the coronary and carotid arteries".

And, "...potential mechanisms by which HDL may exert these anti-atherogenic effects, namely through its role in reverse cholesterol transport, its effects on endothelial cells, and its anti-inflammatory/antioxidant activities".

The results strongly suggested a healthy diet including nuts, coffee, cocoa, grapes, and berries with high levels of HLD may have a profound effect on the prevention of atherosclerosis.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.

In finding a potent ingredient that processes cardioprotection researchers examined the quercetin and polyuronide contents of rapidly dried onion (Allium cepa L. cv. Momiji No. 3) powder (OP) prepared from the outer layers (from second to the fourth scale leaves from the surface) of onion bulbs anti-atherogenic effect.

The study included rats fed a high-fat diet treated by quercetin 4'-glucoside (50%), free quercetin (30%), and quercetin 3,4'-glucoside (20%) as quercetin derivatives in boiling-water extraction.

According to the tested differentiation, in a high-fat diet, Wistar rats, additional OP did not show a significant difference in total cholesterol, HDL-cholesterol, and triglyceride concentrations compared to rats fed a high-fat diet without OP.

However, the atherogenic index (AI) associated with cardiovascular disease risk of Wistar rats fed an OP-added high-fat diet was lower compared to those fed a diet without OP.

Moreover, the incremental elastic modulus (IEM), a measurement of the stiffness of the larger arteries from rats fed the OP-added diet was also significantly lower compared to rats fed by diet without OP.

Additionally, both rat groups were found to exert similar AI and IEM values if the rats fed the diet without OP were allowed spontaneous exercise.

In other words, OP protected the cardio-tissue by exerting an anti-atherogenic effect through other unknown mechanisms associated with regular exercise, without affecting the parameters of cholesterol.

Based on the results, researchers wrote, "These results suggest that OP intake is effective for decreasing the risk of arteriosclerosis".

Taken altogether, onion processed with a higher amount of Onionin A (ONA) may be considered a remedy for the prevention and treatment of arteriosclerosis, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Physicochemical characteristics of rapidly dried onion powder and its anti-atherogenic effect on rats fed high-fat diet by Hamauzu Y1, Nosaka T2, Ito F3, Suzuki T4, Torisu S3, Hashida M5, Fukuzawa A6, Ohguchi M3, Yamanaka. (PubMed).
(2) Atheroprotective effects of HDL: beyond reverse cholesterol transport by Feig JE1, Shamir R, Fisher EA. (PubMed)

#Healthyfood #Onion Supplementation Reduces Significant Motor Incoordination and Memory Deficits By Inhibiting the Expression of #Oxidativestress, Researchers Say

Kyle J. Norton

Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.

In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.

Neurodegenerative disease is the class of condition associated with the progressive loss of neurons occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).

Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into advanced stage.


According to the statistics, dementia affects over 47.5 million people worldwide, and approximately 58 percent are living in low and middle-income countries.

Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019, and two-thirds of people with Alzheimer's disease are women.

Conventionally, as of today, there is no cure for dementia. Treatment of dementia focuses focusing improving dementia symptoms and slowing down the progression of the disease.

Some researchers suggested that the increased incidence of the onset of Alzheimer's disease over the past few decades may be correlated to the promotion of a high-fat diet in the US.

Dr. Rollins CPE, the lead scientist wrote, "HFD-induced obesity during adolescence exacerbated brain volume alterations by adult life in the 3xTg mouse model in comparison to control-fed mice and mediated volumetric alterations of select brain regions, such as the hippocampus".

And, "Further, HFD-induced obesity aggravated memory in all mice, lowering certain memory measures of B6129s control mice to the level of 3xTg mice maintained on a CD. Moreover, a decline in the volumetric trajectories of hippocampal regions for all mice was associated with the degree of spatial memory impairments on the MWM.".

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a closely related of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.

In finding a potential compound for the treatment of cognitive impairment, researchers examined the neuroprotective potential of Allium cepa (A. cepa, Onion) in aluminum chloride-induced animal model neurotoxicity.


The study included mice-induced neurotoxicity by aluminum chloride (50 mg/kg/day) orally was treated supplemented with different doses of A. cepa hydroethanolic extract for a period of 60 days.

Before the treatment of onion, aluminum chloride-treated mice resulted in significant motor incoordination and memory deficits, observed by the increased oxidative stress and elevated levels of acetylcholinesterase (AChE) and aluminum levels in the brain.

Onion supplement injection in aluminum exposed animals not only significantly improved muscle coordination and memory deficits but also decreased the levels of oxidative stress, AChE, and decreased abnormal aluminum deposition induced by the aluminum chloride.

Decreased vacuolated cytoplasm associated with the death of neurons and pyramidal cells in the hippocampal area of the mice brain caused by toxicity was also reversed by the injection of A. cepa supplementation.

The results strongly suggested that onion processes anti-neuro-toxicity induced cognitive impairment in an animal model.

Dr. Singh T, the lead scientist, after taking other factors into account wrote, "significant neuroprotective potential of A. cepa in aluminum-induced neurotoxicity".

Taken together, onion may be considered a neuroprotective remedy, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Neuroprotective effect of Allium cepa L. in aluminium chloride-induced neurotoxicity by Singh T1, Goel RK. (PubMed)
(2) Protective effects of onion-derived quercetin on glutamate-mediated hippocampal neuronal cell death by Yang EJ1, Kim GS, Kim JA, Song KS. (PubMed)
(3) Contributions of a high-fat diet to Alzheimer's disease-related decline: A longitudinal behavioural and structural neuroimaging study in mouse models by Rollins CPE1, Gallino D2, Kong V3, Ayranci G2, Devenyi GA4, Germann J2, Chakravarty MM. (PubMed)

#GreenTea Powder Inhibits #Dementia and #CognitiveImpairment, Researchers Say

Kyle J. Norton

Green tea injection is associated with reduced risk of age-related cognitive decline, a recent study postulated.
Cognitive impairment is a condition of the decline of memory and thinking skills due to aging considered as an early sign of neurodegenerative diseases.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a piece of ginger will solve the problem.

In a total of 12 elderly nursing home residents with cognitive dysfunction, participants who drink green tea powder 2 g/day for 3 months showed a significantly improved cognitive performance and reduced the progression of cognitive dysfunction indicated by the Mini-Mental State Examination Japanese version (MMSE-J) score.

In another study (of Japanese residents aged >60 years from Nakajima, Japan (the Nakajima Project) of 723 participants with normal cognitive function at a baseline survey (2007-2008), 490 completed the follow-up survey in 2011-2013, suggested that the incidence of dementia and cognitive impairment are lower among individuals who consumed green tea 1-6 days per week compared with individuals who did not consume green tea at all.

Additionally, according to the double-blind, randomized controlled study of 39 nursing home residents with cognitive dysfunction (four men, 29 women) divided into two groups either with
consumption of 2 g/day of green tea powder (containing 220.2 mg of catechins) or placebo powder (containing 0.0 mg of catechins), green tea treated group showed a significantly reduced cognitive dysfunction in 3 months follow up in compared to placebo.

The efficacy of green tea in decreased progression of cognitive impairment in the short term may be attributed to ameliorated oxidative stress and levels of low-density lipoprotein.

Taking together, Green tea may have the potential to reduce the risk of early-onset and progression of cognitive decline in the aging population, but long term and large amount injection should be taken with care.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months




Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Green tea consumption affects cognitive dysfunction in the elderly: a pilot study by Ide K1, Yamada H2, Takuma N3, Park M4, Wakamiya N5, Nakase J6, Ukawa Y7, Sagesaka YM8.(PubMed)
(2) Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline by Noguchi-Shinohara M1, Yuki S1, Dohmoto C1, Ikeda Y1, Samuraki M1, Iwasa K1, Yokogawa M2, Asai K3, Komai K4, Nakamura H5,(PubMed)
(3) Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study by Ide K1, Yamada H2, Takuma N3, Kawasaki Y1, Harada S1, Nakase J4, Ukawa Y4, Sagesaka YM4.(PubMed)

#Bromelain Increases the Cytotoxicity of #Cisplatin Significantly in Cancer Treatment, Particularly Peritoneal Mesothelioma, Researchers Suggest

Kyle J. Norton

Peritoneal mesothelioma is a medical condition characterized by irregular cell growth in the tissues of the abdomen (the peritoneum).

Most cases of peritoneal mesothelioma begin in the cell on the surface of the inner lining of the peritoneum, before penetrating into the deeper layers.

At the early stage, due to the small size of the tumor, patients with peritoneal mesothelioma are asymptomatic.

However, at the later stage, patients may experience symptoms of abdominal pain or swelling due to the larger size tumor pressed on the nearby nerve tissues and blood vessels, changes in bowel habits, feeling of fullness, and night sweat accompanied by the general symptoms shared by other types of cancer, such as unexplained weight loss, gastrointestinal discomforts, and loss of appetite.


According to the statistics provided by the American Cancer Society, compared to other types of cancer mesothelioma is rare, with approximately 2,000 to 3,000 new cases of mesothelioma in the US each year. The asbestos-related mesothelioma only accounts for less than 0.3 percent of all cancer diagnosed in the country.

Peritoneal mesothelioma accounts for less than 20 percent of all mesothelioma cases.

Dr. Rodolfo Fonte, the lead scientist in the examination of the risk of asbestos-induced peritoneal mesothelioma in a construction worker, wrote, "Peritoneal mesothelioma is a rare and aggressive asbestos-related malignancy. We present the case of a 65-year-old man who developed recurrent ascites after having been exposed to asbestos in the building industry for > 40 years".

And, "Occupational history and immunohistochemistry are helpful for the correct diagnosis, which, in turn, is important in relation to prognosis and treatment (adoption of new integrated procedures that seem to promise prolonged survival and increased quality of life), and in relation to medico-legal issues and occupation-related compensation claims following asbestos exposure".


Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

With an aim to find a natural ingredient for the treatment of peritoneal mesothelioma, researchers examined the effects of Bromelain (cysteine proteinase) effects on Mucin 1 (MUC1), a glycosylation-dependent protein that confers tumors with invasiveness, metastasis, and chemoresistance.

In the study in which researchers compared the efficacy with the application of various concentrations of bromelain and after 4 and 72 h and combinations of bromelain and cytotoxic drugs (cisplatin or 5-FU) at 72 h, MUC1-expressing MPM cell lines found that bromelain increased the cytotoxicity of cisplatin significantly in cell lines.

Compared to the aforementioned inhibition, combining fluorouracil with bromelain did not show a significant increase in cytotoxicity.

In other words, bromelain improves the chemotherapy depending totally on the types of drugs used for the treatment of peritoneal mesothelioma.

Furthermore, bromelain used alone also showed a significant effect in inducing cell death by apoptosis and autophagy.

In pancreatic and breast cancer cells, injection of bromelain also adversely affected the viability of MUC1 expressing on both cell lines.


Based on the findings, Bromelain used alone or combined with other chemo drugs might have a strong effect on the barrier function of MUC1.

Collectively, bromelain inhibited the progression and proliferation of peritoneal mesothelioma by blocking the activity of the gene MUC1.

Dr. Pillai K, the lead scientist said, "Current evidence indicates that bromelain may have the potential of being developed into an effective anticancer agent for MPM".

Taken together, bromelain may be considered a supplement for the prevention and treatment of peritoneal mesothelioma, pending the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anticancer effect of bromelain with and without cisplatin or 5-FU on malignant peritoneal mesothelioma cells by Pillai K1, Ehteda A, Akhter J, Chua TC, Morris DL. (PubMed)
(2) Anticancer property of bromelain with therapeutic potential in malignant peritoneal mesothelioma by Pillai K1, Akhter J, Chua TC, Morris DL. (PubMed)
(3) Asbestos-induced peritoneal mesothelioma in a construction worker by Rodolfo Fonte, Salvatore Gambettino, Mario Melazzini, Mario Scelsi, Claudio Zanon, and Stefano M Candura. (PMC)