Kyle J. Norton
The colorectum including the large intestine and the rectum is the second part of the digestive system involved in the absorption of water from the small bowel contents and the breaking down of certain materials in the feces into substances some of which are reabsorbed and reused by the body.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining of the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is relatively very common and slowly growing and progresses cancer in a predictable way.
According to the statistics provided by the American Cancer Society, excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
The exact causes of colorectal cancer are unknown. Epidemiologically, the most common risk factors associated with the onset of the disease are
* Age
The disease is more common in people over the age of 50. Regular colonoscopy after the age of 50 is valuable to detect the disease in the early stage.
* Bowl inflammatory diseases
A prolonged period of inflammatory diseases of the colon, such as ulcerative colitis and Crohn’s disease, can increase your risk of colon cancer due to long term inflammation of the lining of the colon.
* Family History of colorectal cancer
People with parents, siblings, children who have had colorectal cancer are more likely to develop colon cancer.
* Inherited Syndromes
Genetic syndromes passed through generations can increase the risk of developing colon cancer.
However, most people with some of the aforementioned prevalent factors have never developed colorectal cancer.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, etc.
With an aim to find a potential compound for the treatment of colorectal cancer, researchers investigated the effects of curcumin nanoformulations anti-cancer activity by overcoming the limitations of the compound.
Application of the nanoformulations not only displayed a greater anticancer activity compared to free curcumin but also extended at the same time non-toxic to the normal cells.
Furthermore, curcumin also demonstrated a strong colorectal cancer effect in the regulation of multiple cell signaling pathways associated with tumor growth and anti-apoptosis.
Moreover, curcumin also promoted the expression of tumor suppressor gene which is crucial in cancer development and progression.
The joint study led by the Ahvaz Jundishapur University of Medical Sciences in the examination of curcumin, a bioactive substance originating from turmeric root anticancer properties showed that curcumin inhibited the expression of a gene associated with involved in tumor initiation and progression. In other words, through inhibition of this gene, curcumin reduced the risk of tumor metastasis.
Additionally, by inhibiting the insulin and insulin-like growth factor-1 receptor curcumin showed a greater decrease in the proliferation and migration of chemoresistant colorectal cancer cells.
Based on the results, Dr. Hosseini SA, the lead scientist said, "These results suggest the possible therapeutic effects of curcumin in adjuvant therapy in metastatic colorectal cancer".
Taken together, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of colorectal cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A Possible Mechanism Underlying the Anti-Growth and Anti-Migration in Chemoresistant Colorectal Cancer Cells by Hosseini SA1, Zand H2, Cheraghpour M. (PubMed)
(2) Curcumin Nanoformulations for Colorectal Cancer: A Review by Wong KE1,2, Ngai SC3, Chan KG4,5, Lee LH1,2,6, Goh BH1,2,6, Chuah LH. (PubMed)
(3) Bowel (Colorectal ) Cancer by Kyle J. Norton
Monday, 11 September 2023
#Brassica rapa Inhibits Liver Oxidativestress Markers and Pathways Associated with the Onset of #Liverdieases, Researchers Find
Kyle J. Norton
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reduction of partly or completely the function of the liver, including liver failure.
The most common types of liver disease in the US are
* Hepatitis C (26%) is a liver disease caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
* Alcoholic liver disease (21%) is a condition that caused long-term excessive alcohol drinking. It is known that years of alcohol abuse can cause the liver to become inflamed and swollen. Over time, it has been found to induce the formation of liver scars, known as cirrhosis. Cirrhosis is the final stage of liver disease.
* Hepatitis C plus alcoholic liver disease (15%).
* Cryptogenic causes (18%) is a condition with no apparent underlying reason. However, most researchers suggested that many cases of cryptogenic cirrhosis are likely caused by non-alcoholic fatty liver disease (NAFLD), a condition of fat accumulated in the liver.
* Hepatitis B and D (15%) are liver diseases caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
Human toxicity is a general term that refers to any substance which causes harm to human health if inhaled, ingested, or absorbed through the skin.
Liver toxicity is a process that causes liver damage by reducing the function of the liver.
Liver oxidative stress caused by a toxic substance such as an overdose of the supplement has been found to constitute most cases of acute liver damage.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of liver diseases, researchers examined the hepatoprotective effects of B. Rapa polysaccharides (BRPs) on acute liver injury induced by carbon tetrachloride (CCl4 ) in mice.
According to the results of Mice treated with CCl4 after the oral administration of BRPs (55, 110, and 220 mg/kg) or bifendate (100 mg/kg) for 7 days,
* BRP pre-treatment significantly decreased the enzymatic activities of liver oxidative stress markers ALT, ALP, and AST in the serum, by increasing the activities of antioxidant enzymes SOD and GSH-Px in the liver and reduced the MDA concentration in the liver.
* BRPs alleviated hepatocyte injury and markedly inhibited the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6.
* Furthermore, BRPs downregulated the CCl4 -induced hepatic tissue expression of caspase-3 involved in cell apoptosis.
* Moreover, BRPs inhibited the JAK2/STAT3 signaling pathway associated with the inhibition of cell division and stimulation of inflammation in a dose-dependent manner in the liver.
Based on the results, researchers wrote, " BRPs exert hepatoprotective effect against the CCl4 -induced liver injury via modulating the apoptotic and inflammatory responses and downregulating the JAK2/STAT3 signaling pathway".
Taken together, Brassica rapa may be considered supplementation for the prevention of acute liver damage, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Brassica rapa Polysaccharides Ameliorate CCl4 -Induced Acute Liver Injury in Mice through Inhibiting Inflammatory Apoptotic Response and Oxidative Stress by Li Q1, Yang H1, Wang W2, Li N1, Zou X1, Li Y2, Fan G1, Zhang Y1,2, Kuang T. (PubMed)
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reduction of partly or completely the function of the liver, including liver failure.
The most common types of liver disease in the US are
* Hepatitis C (26%) is a liver disease caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
* Alcoholic liver disease (21%) is a condition that caused long-term excessive alcohol drinking. It is known that years of alcohol abuse can cause the liver to become inflamed and swollen. Over time, it has been found to induce the formation of liver scars, known as cirrhosis. Cirrhosis is the final stage of liver disease.
* Hepatitis C plus alcoholic liver disease (15%).
* Cryptogenic causes (18%) is a condition with no apparent underlying reason. However, most researchers suggested that many cases of cryptogenic cirrhosis are likely caused by non-alcoholic fatty liver disease (NAFLD), a condition of fat accumulated in the liver.
* Hepatitis B and D (15%) are liver diseases caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
Human toxicity is a general term that refers to any substance which causes harm to human health if inhaled, ingested, or absorbed through the skin.
Liver toxicity is a process that causes liver damage by reducing the function of the liver.
Liver oxidative stress caused by a toxic substance such as an overdose of the supplement has been found to constitute most cases of acute liver damage.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of liver diseases, researchers examined the hepatoprotective effects of B. Rapa polysaccharides (BRPs) on acute liver injury induced by carbon tetrachloride (CCl4 ) in mice.
According to the results of Mice treated with CCl4 after the oral administration of BRPs (55, 110, and 220 mg/kg) or bifendate (100 mg/kg) for 7 days,
* BRP pre-treatment significantly decreased the enzymatic activities of liver oxidative stress markers ALT, ALP, and AST in the serum, by increasing the activities of antioxidant enzymes SOD and GSH-Px in the liver and reduced the MDA concentration in the liver.
* BRPs alleviated hepatocyte injury and markedly inhibited the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6.
* Furthermore, BRPs downregulated the CCl4 -induced hepatic tissue expression of caspase-3 involved in cell apoptosis.
* Moreover, BRPs inhibited the JAK2/STAT3 signaling pathway associated with the inhibition of cell division and stimulation of inflammation in a dose-dependent manner in the liver.
Based on the results, researchers wrote, " BRPs exert hepatoprotective effect against the CCl4 -induced liver injury via modulating the apoptotic and inflammatory responses and downregulating the JAK2/STAT3 signaling pathway".
Taken together, Brassica rapa may be considered supplementation for the prevention of acute liver damage, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Brassica rapa Polysaccharides Ameliorate CCl4 -Induced Acute Liver Injury in Mice through Inhibiting Inflammatory Apoptotic Response and Oxidative Stress by Li Q1, Yang H1, Wang W2, Li N1, Zou X1, Li Y2, Fan G1, Zhang Y1,2, Kuang T. (PubMed)
#Cocoa Polyphenol Extracts Alone or Combined with Beta-Sitosterol Process Antiproliferative Effects in Cancers, According to Studies
Kyle J. Norton
Cancer cell proliferation is the rapid reproduction of invasive cells in malignant tumors.
In other words, instead of dividing the number of times before replacing it with new cells, the cancer cells can divide indefinitely.
Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ, caused by irregular cell growth in the tissue or specific organ in the body due to the alternation of cell DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American Cancer Society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Anti-proliferative activity is the process of inhibiting cell growth and antiproliferative effects on tumor cells.
The cocoa bean or simply cocoa is the dried and fully fermented seed of Theobroma cacao, which appeared in different cultures worldwide for hundreds of years, particularly in many ancient South American countries.
In finding a potential phytochemical for the prevention and treatment of cancer, researchers examined the inhibitory effect of different cocoa polyphenol extracts, alone or combined with beta-sitosterol, on two human prostate cancer cell lines (nonmetastatic 22Rv1 cells and metastatic DU145 cells) and a normal human prostate cell line (RWEP-1).
According to the experimental analysis of cells treated independently with five products from 1 to 72 h: (1/) synthetic beta-sitosterol, (2/) a cocoa polyphenols extract supplemented with beta-sitosterol, (3/) three different cocoa polyphenols extracts naturally containing beta-sitosterol, at the highest tested concentration, cocoa polyphenols extracts induced a complete inhibition of growth of metastatic and nonmetastatic cancer cell lines.
Furthermore, cocoa polyphenol extracts alone were more active against local cancer cells than against metastatic cells,.
However, at the highest tested concentration, cocoa polyphenol extract alone is not effective on normal prostate cell lines.
On the other hand, beta-sitosterol induced low growth inhibition of both cancer cell lines, compared to cocoa polyphenols extracts which are significantly more active and showed strong and fast inhibition of cell growth than beta-sitosterol alone.
There is no synergy or addition that was observed when beta-sitosterol was tested together with the cocoa polyphenols extract.
Based on the findings, researchers said, "Our results show that cocoa polyphenols extracts have an antiproliferative effect on prostate cancer cell growth but not on normal cells, at the highest tested concentration".
Taken together, beta-sitosterol may be considered a supplement for the prevention and treatment of stomach cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells by Jourdain C1, Tenca G, Deguercy A, Troplin P, Poelman D. (PubMed)
Cancer cell proliferation is the rapid reproduction of invasive cells in malignant tumors.
In other words, instead of dividing the number of times before replacing it with new cells, the cancer cells can divide indefinitely.
Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ, caused by irregular cell growth in the tissue or specific organ in the body due to the alternation of cell DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American Cancer Society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Anti-proliferative activity is the process of inhibiting cell growth and antiproliferative effects on tumor cells.
The cocoa bean or simply cocoa is the dried and fully fermented seed of Theobroma cacao, which appeared in different cultures worldwide for hundreds of years, particularly in many ancient South American countries.
In finding a potential phytochemical for the prevention and treatment of cancer, researchers examined the inhibitory effect of different cocoa polyphenol extracts, alone or combined with beta-sitosterol, on two human prostate cancer cell lines (nonmetastatic 22Rv1 cells and metastatic DU145 cells) and a normal human prostate cell line (RWEP-1).
According to the experimental analysis of cells treated independently with five products from 1 to 72 h: (1/) synthetic beta-sitosterol, (2/) a cocoa polyphenols extract supplemented with beta-sitosterol, (3/) three different cocoa polyphenols extracts naturally containing beta-sitosterol, at the highest tested concentration, cocoa polyphenols extracts induced a complete inhibition of growth of metastatic and nonmetastatic cancer cell lines.
Furthermore, cocoa polyphenol extracts alone were more active against local cancer cells than against metastatic cells,.
However, at the highest tested concentration, cocoa polyphenol extract alone is not effective on normal prostate cell lines.
On the other hand, beta-sitosterol induced low growth inhibition of both cancer cell lines, compared to cocoa polyphenols extracts which are significantly more active and showed strong and fast inhibition of cell growth than beta-sitosterol alone.
There is no synergy or addition that was observed when beta-sitosterol was tested together with the cocoa polyphenols extract.
Based on the findings, researchers said, "Our results show that cocoa polyphenols extracts have an antiproliferative effect on prostate cancer cell growth but not on normal cells, at the highest tested concentration".
Taken together, beta-sitosterol may be considered a supplement for the prevention and treatment of stomach cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells by Jourdain C1, Tenca G, Deguercy A, Troplin P, Poelman D. (PubMed)
#Sulforaphane (SFN) Found in #CruciferousVegetables Reduce the Risk of #CardiovascularDiseases (CVD) and #Cancer, Researchers Find
Kyle J. Norton
Chronic diseases are medical conditions that last more than 3 months depending on the type of disease.
In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.
According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.
Cardiovascular diseases are chronic diseases that refer to heart diseases, affecting millions of people in the world. According to statistics, over 17.7 million people died from CVDs in 2015.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, which causes damage to the heart tissue and reduced function of the arteries.
Hyperlipidemia and hypertension are the risk factors of the diseases.
According to the statistics cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware that heart disease is such a risk for them, according to Jean Hailes for Women Health in the article Cardiovascular Health.
According to statistics, heart disease is the second leading cause of death, claiming more than 48,000 lives every year.in Canada.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
In finding a potential remedy for the prevention and treatment of cardiovascular diseases, researchers the effect of sulforaphane against cardiovascular disease via Nrf2 activation.
According to the results of the experiment,
* Sulforaphane (SFN) is an ITC that exerted anticancer activity in both in vivo and epidemiological studies.
* SFN demonstrated strong antioxidant and anti-inflammatory properties in CVD.
* SFN-activated NF-E2-related factor 2 (Nrf2) that serves as a defense mechanism against oxidative stress and electrophilic toxicants by inducing more than a hundred cytoprotective proteins, including antioxidants and phase II detoxifying enzymes.
Based on the results, researchers said, "the evidence from clinical studies and animal experiments relating to the potential mechanisms by which SFN modulates Nrf2 activation and protects against CVD".
Taken together, cruciferous vegetables may be considered functional remedies for the prevention of CVD, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye FloatersContrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How to Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation by Bai Y1, Wang X2, Zhao S3, Ma C4, Cui J5, Zheng Y. (PubMed)
Chronic diseases are medical conditions that last more than 3 months depending on the type of disease.
In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.
According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.
Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.
Cardiovascular diseases are chronic diseases that refer to heart diseases, affecting millions of people in the world. According to statistics, over 17.7 million people died from CVDs in 2015.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, which causes damage to the heart tissue and reduced function of the arteries.
Hyperlipidemia and hypertension are the risk factors of the diseases.
According to the statistics cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware that heart disease is such a risk for them, according to Jean Hailes for Women Health in the article Cardiovascular Health.
According to statistics, heart disease is the second leading cause of death, claiming more than 48,000 lives every year.in Canada.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
In finding a potential remedy for the prevention and treatment of cardiovascular diseases, researchers the effect of sulforaphane against cardiovascular disease via Nrf2 activation.
According to the results of the experiment,
* Sulforaphane (SFN) is an ITC that exerted anticancer activity in both in vivo and epidemiological studies.
* SFN demonstrated strong antioxidant and anti-inflammatory properties in CVD.
* SFN-activated NF-E2-related factor 2 (Nrf2) that serves as a defense mechanism against oxidative stress and electrophilic toxicants by inducing more than a hundred cytoprotective proteins, including antioxidants and phase II detoxifying enzymes.
Based on the results, researchers said, "the evidence from clinical studies and animal experiments relating to the potential mechanisms by which SFN modulates Nrf2 activation and protects against CVD".
Taken together, cruciferous vegetables may be considered functional remedies for the prevention of CVD, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye FloatersContrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How to Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation by Bai Y1, Wang X2, Zhao S3, Ma C4, Cui J5, Zheng Y. (PubMed)
#PrudentPattern and #VegetarianDietaryPattern Inhibit #Westerndiet in InducingThe Risk of #MetabolicSyndrome, Researchers Say
Kyle J. Norton
The Western pattern diet or typical American diet is a modern dietary pattern associated with a high intake of processed foods, red meat, processed meat, fried and refined foods, and high sugar.
The Western pattern diet has also been found to induce chronic diseases. Dr. Hariharan D, the lead scientist wrote, "Characteristics of the Western diet that fueled the obesity epidemic may also impact kidney disease incidence and progression. Enlarging portion sizes over the past half-century have been accompanied by increased intake of protein, sodium, and processed foods while consumption of fruits and vegetables has declined".
And, ", the Western diet, characterized by high intake of red meat, animal fat, sweets, and desserts and low intake of fresh fruits and vegetables and low-fat dairy products, increases risk of chronic diseases".
The results clearly suggested, that if you are following a traditional diet with high fruits and vegetables and fewer processed food, saturated and trans fat, and red meat accompanied by moderate exercise daily, you are at a substantially decreased risk of chronic disease, compared to those who follow the Western diet.
Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular disease and diabetes, including too much fat around the waist, high blood pressure, triglycerides, and blood sugar, and low HDL cholesterol.
In other words, if you process 3 of the aforementioned conditions, you are at a higher risk of heart disease, stroke, and diabetes. However, most people with metabolic syndrome have never developed
CVD and diabetes.
Other than high blood glucose, most patients with metabolic conditions are asymptomatic.
Epidemiologically, aging, ethnicity, obesity, medical conditions such as diabetes, nonalcoholic fatty liver disease, and polycystic ovary syndrome are the most common risk factors found in patients with the syndrome.
Green peas are a species of Pisum Sativum belonging to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalayas Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
In finding a potent ingredient for the reduced risk of cardiovascular disease and diabetes, researchers investigated the association between major dietary patterns and the prevalence of metabolic syndrome in individuals with impaired glucose tolerance.
The cross-sectional study included a total of 425 subjects 35 to 55 years of age. According to the returned food-frequency questionnaire from participants,
* The Western pattern with a high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs was associated with greater odds of having increased triacylglycerol (odds ratio 1.76, 95% confidence interval 1.01-3.07) and blood pressure (odds ratio 2.62, 95% confidence interval 1.32-5.23).
* The prudent pattern with a high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables was associated with a prevalence of low high-density lipoprotein cholesterol levels (odds ratio 0.55, 95% confidence interval 0.31-0.96).
* The vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level (odds ratio 2.26, 95% confidence interval 1.25-4.06).
Based on the findings, researchers said, "Major dietary patterns were significantly associated with the risk of metabolic syndrome".
Taken together, People who follow the Western diet are at a higher risk of cardiovascular disease and diabetes comapred to other dietary patterns.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
(2) The Western Diet and Chronic Kidney Disease by Hariharan D1, Vellanki K, Kramer H. (PubMed)
The Western pattern diet or typical American diet is a modern dietary pattern associated with a high intake of processed foods, red meat, processed meat, fried and refined foods, and high sugar.
The Western pattern diet has also been found to induce chronic diseases. Dr. Hariharan D, the lead scientist wrote, "Characteristics of the Western diet that fueled the obesity epidemic may also impact kidney disease incidence and progression. Enlarging portion sizes over the past half-century have been accompanied by increased intake of protein, sodium, and processed foods while consumption of fruits and vegetables has declined".
And, ", the Western diet, characterized by high intake of red meat, animal fat, sweets, and desserts and low intake of fresh fruits and vegetables and low-fat dairy products, increases risk of chronic diseases".
The results clearly suggested, that if you are following a traditional diet with high fruits and vegetables and fewer processed food, saturated and trans fat, and red meat accompanied by moderate exercise daily, you are at a substantially decreased risk of chronic disease, compared to those who follow the Western diet.
Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular disease and diabetes, including too much fat around the waist, high blood pressure, triglycerides, and blood sugar, and low HDL cholesterol.
In other words, if you process 3 of the aforementioned conditions, you are at a higher risk of heart disease, stroke, and diabetes. However, most people with metabolic syndrome have never developed
CVD and diabetes.
Other than high blood glucose, most patients with metabolic conditions are asymptomatic.
Epidemiologically, aging, ethnicity, obesity, medical conditions such as diabetes, nonalcoholic fatty liver disease, and polycystic ovary syndrome are the most common risk factors found in patients with the syndrome.
Green peas are a species of Pisum Sativum belonging to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalayas Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
In finding a potent ingredient for the reduced risk of cardiovascular disease and diabetes, researchers investigated the association between major dietary patterns and the prevalence of metabolic syndrome in individuals with impaired glucose tolerance.
The cross-sectional study included a total of 425 subjects 35 to 55 years of age. According to the returned food-frequency questionnaire from participants,
* The Western pattern with a high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs was associated with greater odds of having increased triacylglycerol (odds ratio 1.76, 95% confidence interval 1.01-3.07) and blood pressure (odds ratio 2.62, 95% confidence interval 1.32-5.23).
* The prudent pattern with a high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables was associated with a prevalence of low high-density lipoprotein cholesterol levels (odds ratio 0.55, 95% confidence interval 0.31-0.96).
* The vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level (odds ratio 2.26, 95% confidence interval 1.25-4.06).
Based on the findings, researchers said, "Major dietary patterns were significantly associated with the risk of metabolic syndrome".
Taken together, People who follow the Western diet are at a higher risk of cardiovascular disease and diabetes comapred to other dietary patterns.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
(2) The Western Diet and Chronic Kidney Disease by Hariharan D1, Vellanki K, Kramer H. (PubMed)
#MonofloralHoney Process Anti- Human immunodeficiency Virus HIV-1 Through Inhibiting Effect of Methylglyoxal, Researchers Say
Kyle J. Norton
Honey may have a profound effect in reducing the risk and treatment of HIV-1, some scientists suggested.
Human immunodeficiency virus HIV-1 is the most widespread type worldwide that can lead to acquired immunodeficiency syndrome (AIDS).
Acquired immunodeficiency syndrome (AIDS) is a chronic condition caused by the infection of the human immunodeficiency virus (HIV).
According to epidemiological studies, people who serval sexual partners are the most at risk of HIV infection.
However, the virus can also be transmitted through infected blood transfusion, and infected mother to children.
Most people infected by the HIV virus may experience symptoms of fever, muscle aches, and joint pain similar to those of influenza in the early stage of the viral attacks.
At the final stage of the infection, the virus can weaken the immune system to the point that causes the onset of AIDS and induces more severe symptoms including the general symptoms of cancers accompanied by soaking night sweats, recurring fever, and persistent white spots or unusual lesions on your tongue or in your mouth.
Dr. Seth C Kalichman and colleagues in the infectious team, concerned about the risk of HIV in people with multiple sexual partners in the examining the 209 HIV-positive men and 291 HIV-positive women recruited conveniently from HIV/AIDS support groups and antiretroviral clinics found that 63% and 309 (62%) participants were currently sexually active, of whom 247 (80%) reported only one sex partner in the previous 3 months and 62 (20%) reported two or more partners during that time".
Although the use of a condom may have some protective effects in the prevention of HIV transmitting disease, however, the team said, "Steady sex partners of participants with multiple partnerships were significantly less likely to be protected by condoms than steady partners of individuals with only one sex partner".
Dangerously, in the final report, the team wrote, "Individuals with multiple sex partners were also significantly less likely to have disclosed their HIV status".
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient or whole food for the inhibition of human immunodeficiency virus HIV-1 before they can cause acquired immunodeficiency syndrome (AIDS), researchers evaluated the anti-HIV-1 activity of eight different kinds of honey.
The tested Monofloral Iranian honey from eight floral sources was analyzed to determine their anti-HIV-1 activities as well as their effects on lymphocyte proliferation.
According to the quantitative polymerase chain reaction (PCR) assay and high pure viral nucleic acid kit, 6 out of 8 monofloral kinds of honey from Petro selinum sativum, Nigella sativa, Citrus sinensis, Zataria multiflora, Citrus aurantium, and Zizyphus mauritiana flowers exerted a significantly inhibitory HIV-1 activity at different doses.
The half-maximal effective concentration (EC50) values of 6 out of 8 monofloral kinds of honey are 37.5, 88, 70, 88, 105, and 5 µg/ml respectively.
The monofloral Iranian kinds of honey from Astragalus gummier and Chamaemelum Nobile flowers had a weak anti-HIV-1 activity, compared to others.
The frequency and intensity of cluster of differentiation CD4 expression on Peripheral blood mononuclear cells (PBMC) increased in the presence of all honey types, an indication of immune activity.
Peripheral blood mononuclear cells (PBMC) are round nucleus peripheral blood cells consisting of lymphocytes (T cells, B cells, NK cells), and CD4 cells or T4 helpers play critical roles to send signals to other types of immune cells with a function to destroy invasive pathogens.
Treatment with monofloral kinds of honey from Z. multiflora and N. Sativa also increased the CD19 markers for normal and neoplastic B cells.
According to the spectroscopic analysis, monofloral kinds of honey from P. sativum, N. sativa, Z. multiflora, and Z. mauritiana flowers processed a potency to be anti-HIV-1 agents.
In in-depth differentiation, researchers showed that the inhibitory effect of methylglyoxal is higher in the late stage of HIV-1 infection.
The chemical compound found to exert anti-HIV-1 activity was methylglyoxal.
Taken together, monofloral kinds of honey containing high amounts bioactive compound methylglyoxal may be considered a functional food for the prevention of HIV-1 infection and combined with the primary therapy for the treatment of AIDs.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Anti-HIV-1 activity of eight monofloral Iranian honey types by Behbahani M1. (PubMed)
(2) Recent multiple sexual partners and HIV transmission risks among people living with HIV/AIDS in Botswana by Seth C Kalichman, Dolly Ntseane, Keitseope Nthomang, Mosarwa Segwabe, Odireleng Phorano, and Leickness C Simbayi. (PMC)
Honey may have a profound effect in reducing the risk and treatment of HIV-1, some scientists suggested.
Human immunodeficiency virus HIV-1 is the most widespread type worldwide that can lead to acquired immunodeficiency syndrome (AIDS).
Acquired immunodeficiency syndrome (AIDS) is a chronic condition caused by the infection of the human immunodeficiency virus (HIV).
According to epidemiological studies, people who serval sexual partners are the most at risk of HIV infection.
However, the virus can also be transmitted through infected blood transfusion, and infected mother to children.
Most people infected by the HIV virus may experience symptoms of fever, muscle aches, and joint pain similar to those of influenza in the early stage of the viral attacks.
At the final stage of the infection, the virus can weaken the immune system to the point that causes the onset of AIDS and induces more severe symptoms including the general symptoms of cancers accompanied by soaking night sweats, recurring fever, and persistent white spots or unusual lesions on your tongue or in your mouth.
Dr. Seth C Kalichman and colleagues in the infectious team, concerned about the risk of HIV in people with multiple sexual partners in the examining the 209 HIV-positive men and 291 HIV-positive women recruited conveniently from HIV/AIDS support groups and antiretroviral clinics found that 63% and 309 (62%) participants were currently sexually active, of whom 247 (80%) reported only one sex partner in the previous 3 months and 62 (20%) reported two or more partners during that time".
Although the use of a condom may have some protective effects in the prevention of HIV transmitting disease, however, the team said, "Steady sex partners of participants with multiple partnerships were significantly less likely to be protected by condoms than steady partners of individuals with only one sex partner".
Dangerously, in the final report, the team wrote, "Individuals with multiple sex partners were also significantly less likely to have disclosed their HIV status".
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient or whole food for the inhibition of human immunodeficiency virus HIV-1 before they can cause acquired immunodeficiency syndrome (AIDS), researchers evaluated the anti-HIV-1 activity of eight different kinds of honey.
The tested Monofloral Iranian honey from eight floral sources was analyzed to determine their anti-HIV-1 activities as well as their effects on lymphocyte proliferation.
According to the quantitative polymerase chain reaction (PCR) assay and high pure viral nucleic acid kit, 6 out of 8 monofloral kinds of honey from Petro selinum sativum, Nigella sativa, Citrus sinensis, Zataria multiflora, Citrus aurantium, and Zizyphus mauritiana flowers exerted a significantly inhibitory HIV-1 activity at different doses.
The half-maximal effective concentration (EC50) values of 6 out of 8 monofloral kinds of honey are 37.5, 88, 70, 88, 105, and 5 µg/ml respectively.
The monofloral Iranian kinds of honey from Astragalus gummier and Chamaemelum Nobile flowers had a weak anti-HIV-1 activity, compared to others.
The frequency and intensity of cluster of differentiation CD4 expression on Peripheral blood mononuclear cells (PBMC) increased in the presence of all honey types, an indication of immune activity.
Peripheral blood mononuclear cells (PBMC) are round nucleus peripheral blood cells consisting of lymphocytes (T cells, B cells, NK cells), and CD4 cells or T4 helpers play critical roles to send signals to other types of immune cells with a function to destroy invasive pathogens.
Treatment with monofloral kinds of honey from Z. multiflora and N. Sativa also increased the CD19 markers for normal and neoplastic B cells.
According to the spectroscopic analysis, monofloral kinds of honey from P. sativum, N. sativa, Z. multiflora, and Z. mauritiana flowers processed a potency to be anti-HIV-1 agents.
In in-depth differentiation, researchers showed that the inhibitory effect of methylglyoxal is higher in the late stage of HIV-1 infection.
The chemical compound found to exert anti-HIV-1 activity was methylglyoxal.
Taken together, monofloral kinds of honey containing high amounts bioactive compound methylglyoxal may be considered a functional food for the prevention of HIV-1 infection and combined with the primary therapy for the treatment of AIDs.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Anti-HIV-1 activity of eight monofloral Iranian honey types by Behbahani M1. (PubMed)
(2) Recent multiple sexual partners and HIV transmission risks among people living with HIV/AIDS in Botswana by Seth C Kalichman, Dolly Ntseane, Keitseope Nthomang, Mosarwa Segwabe, Odireleng Phorano, and Leickness C Simbayi. (PMC)
#Herbal #Angelica Sinensis (RAS) Supplementation Inhibits Gene Expression Associated with an Increased Weight Loss in Obesity, Researchers Find
Kyle J. Norton
Obesity is a medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.
The most common causes of obesity are associated with
* An increased intake of energy-dense foods that are high in saturated and trans fat, processed foods, and red meat.
* An increase in physical inactivity.
That leads to the accumulation of visceral fat in the body
Visceral fat in obesity is associated with 90% of patients with ischemic heart disease. In obese, accumulation of visceral fat is predominant in the intra-abdominal cavity.
Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.
However, in non-obese subjects, visceral fat accumulation is correlated with glucose intolerance, hyperlipidemia, and hypertension.
Obesity rates have increased for all age groups in the US over the last several decades, coincidently with the periods that promoted the Western diet.
The WHO in the explanation of the causes of obesity wrote, "Changes in dietary and physical activity patterns are often the result of environmental and societal changes associated with the development and lack of supportive policies in sectors such as health, agriculture, transport, urban planning, environment, food processing, distribution, marketing, and education".
Certain medical conditions such as hypothyroidism, polycystic ovary syndrome, Cushing's syndrome,..., genetic preposition, and use of certain medications that can cause weight gain or water retention, such as corticosteroids, antidepressants or some seizure medications, also increase the risk of overweight and obesity.
In finding a natural ingredient for the prevention of overweight, scientists examined the root of Angelica sinensis (RAS) supplementation effects on FTO gene expression and methylation status in body weight on an animal model,
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to tested analysis, high-fat-diet (HFD) induced obese female mouse that was divided into groups according to RAS dosage in the diet as follows: normal diet, HFD diet (HC), HFD with low-dosage RAS (DL), HFD with medium-dosage RAS (DM), and HFD with high-dosage RAS (DH). After RAS supplementation for 4 weeks,
* Bodyweight suppression and FTO expression associated with reduced weight in DH mice were significantly higher compared to HC mice and no significant change in FTO expression was detected between DM and DL mice or in their offspring.
* Furthermore, CpG island (the regions with a high frequency of CpG sites) in the FTO promoter was hypermethylated up to 95.44% in the HC group, 91.67% in the DH group, and 90.00% in the normal diet group.
* Most importantly, the adipocyte expression in the DH group was smaller than those in the HC group.
These results strongly suggested that RAS may have a potential role in the inhibition of obesity.
Based on the results, researchers suggest, that "RAS could ameliorate obesity induced by HFD and that the molecular mechanism might be associated with the expression of the FTO gene".
Taken altogether, Dandelion may be considered a remedy for the treatment of obesity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis Suppresses Body Weight Gain and Alters Expression of the FTO Gene in High-Fat-Diet Induced Obese Mice by Zhong T1, Duan XY1, Zhang H1, Li L1, Zhang HP1, Niu L. (PubMed).
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