Kyle J. Norton
The heart muscle or myocardium is one of three types of muscles in humans, that build the walls of the heart.
The most common diseases of heart muscle include angina pectoris myocardial infarction, and other heart muscle disease caused by restricting blood supply to the muscle.
The most common symptoms of heart muscle diseases include tightness, pain, or swelling of the legs, ankles, and feet
Some patients may also experience symptoms of gastrointestinal discomforts include bloating, abdominal pain and shortness of breath caused by the reduced blood supply.
The most common risk factors associated with heart muscle disease include high blood pressure, heart tissue damage, heart problems, metabolic syndrome, nutritional deficiencies, excessive alcohol drinking.
Some researchers suggested that genetic preposition may have a strong effect on the induction of heart muscle disease.
The Genetics Home Reference wrote, " mutations in more than 30 genes have been found to cause familial dilated cardiomyopathy. These genes provide instructions for making proteins that are found in cardiac muscle cells called cardiomyocytes.
And, "Mutations in one gene, TTN, account for approximately 20 percent of cases of familial dilated cardiomyopathy".
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
In finding a natural ingredient that protects the heart muscle against the onset of cardiovascular disease researchers examined the 3, 3'-Diindolylmethane (DIM) effects on cardiomyocytes.
Tested cell lines H9C2 used in the study were evaluated by DIM's influence on inflammation and apoptosis of cardiomyocytes induced by LPS. H9C2 cells incubated with DIM (10, 20, and 30 μM) with or without LPS for 24 h.
Treatment with various concentrations of DIM (10, 20, and 30 μM) inhibited the overabundance of pro-inflammatory cytokines (TNF-α and IL-6 mRNA expression) induced by LPS.
In other words, DIM normalized the levels of impaired TNF-α and IL-6 mRNA expression, in the LPS + DIM30(μM) group.
According to the tested assays, DIM treatment significantly blocked LPS-induced oxidative stress and inhibited LPS-induced apoptosis in H9C2 cardiomyocytes.
Furthermore, DIM significantly inhibited the LPS-induced expression of a protein associated with proapoptosis and enhanced the expression of a protein involved in anti-apoptosis.
Dr. Luo Q, the lead scientist, wrote in the final report, "DIM may have a protective effect for H9C2 cardiomyocytes against LPS-induced inflammatory response and apoptosis. DIM may be a new insight into the treatment of septic cardiomyopathy".
In order to find out more information about DIM anti-cardiovascular disease activity, researchers evaluated the function of DIM on hypoxia‑induced cardiac injury.
The study included H9c2 cells pretreated with DIM (1, 5 and 10 µM) for 12 h and exposed to hypoxia for 12 h.
DIM with different doses extended markedly attenuated the increased transcription of pro-inflammatory cytokines (interleukin (IL)‑1β, IL‑6, and tumor necrosis factor‑α) induced by hypoxia.
DIM also modulated the genes associated with transcription of autophagy, compared with the hypoxia group.
DIM also protected the cells against apoptosis by inhibiting and exhibiting the proteins associated with anti-apoptosis and pro-apoptosis, respectively.
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the protection of heart muscle against the risk of heart disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3,3'-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis by Luo Q1,2,3, Yang A1,2,3, Cao Q1,2,3, Guan H. (PubMed)
(2) 3,3'‑Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells by Liang K1, Qian WH1, Zong J. (PubMed)
(3) Familial dilated cardiomyopathy by The Genetics Home Reference. (NIH)
Tuesday, 5 September 2023
#Herbal #Turmeric Inhibits Kidney Damage and Injury Associated with Drugs, Heavy Metals and Substances Toxicity, Researchers Say
Kyle J. Norton
The kidneys are a pair of kidney-shaped organs located on either side of your spine with a function to filter out the wastes from the blood before passing the wastes through urinary secretion.
More than a detoxed organ, the kidneys also maintain the body fluid balance and regulate the production of red blood cells and high blood pressure.
Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.
Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.
The advance of CKD can cause dangerous levels of fluid, electrolytes, and waste build-up in the body.
According to statistics, approximately 14 percent of the US general population suffers from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.
Out of many risk factors associated with CKD, some researchers suggest high blood pressure is one most prevalent risk factors found in most patients.
The Natural Kidney Foundation wrote, "More than half the people with chronic kidney disease (CKD) have high blood pressure. High blood pressure increases the chance that kidney disease will get worse"
And "Following your treatment plan carefully and keeping your blood pressure under control can help to prevent these complications".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound with kidney protective properties, researchers investigated curcumin, a major phenolic compound the rhizome of the Curcuma species kidney toxicity.
In glucose, tartrazine-induced toxicity, curcumin protected the kidney against DNA damage in leucocytes.
In a streptozotocin-induced diabetes rat model, curcumin protected the kidney against overexpression of free radicals to cause kidney cell damage through its antioxidant activity.
In the long-term heavy metal model, curcumin inhibited the toxic effect caused by the accumulation of the metal in the induction of kidney cell damage.
In an animal model induced cisplatin-induced acute kidney injury by injection of cisplatin, curcumin enhanced the function of cisplatin-resistant cancer cells and decreased its unwanted side effects.
More interestingly, curcumin inhibited the nicotine receptors on kidney cells that link nicotine to accelerated kidney damage in cigarette smokers
In other words. if the kidneys are less able to excrete nicotine, in the long term, accumulated extracellular fluid and blood volumes increase, which can lead to severe kidney damage.
In other studies, kidney damage caused by maleate, malathion, nicotine, cisplatin, gentamicin, and methotrexate was also reversed by the injection of curcumin, similar to those of the aforementioned substances.
Taken altogether, turmeric and its bioactive compound curcumin may be considered remedies for the prevention and treatment of kidney damage, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis by Ramadan G1, El-Menshawy O. (PubMed)
(2) Protective effects of curcumin against toxic agents-induced renal failure: a review by Farkhondeh T1, Samarghandian S2, Azimi-Nezhad M2, Shahri AMP. (PubMed)
(3) High Blood Pressure and Chronic Kidney Disease by The Natural Kidney Foundation
The kidneys are a pair of kidney-shaped organs located on either side of your spine with a function to filter out the wastes from the blood before passing the wastes through urinary secretion.
More than a detoxed organ, the kidneys also maintain the body fluid balance and regulate the production of red blood cells and high blood pressure.
Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.
Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.
The advance of CKD can cause dangerous levels of fluid, electrolytes, and waste build-up in the body.
According to statistics, approximately 14 percent of the US general population suffers from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.
Out of many risk factors associated with CKD, some researchers suggest high blood pressure is one most prevalent risk factors found in most patients.
The Natural Kidney Foundation wrote, "More than half the people with chronic kidney disease (CKD) have high blood pressure. High blood pressure increases the chance that kidney disease will get worse"
And "Following your treatment plan carefully and keeping your blood pressure under control can help to prevent these complications".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound with kidney protective properties, researchers investigated curcumin, a major phenolic compound the rhizome of the Curcuma species kidney toxicity.
In glucose, tartrazine-induced toxicity, curcumin protected the kidney against DNA damage in leucocytes.
In a streptozotocin-induced diabetes rat model, curcumin protected the kidney against overexpression of free radicals to cause kidney cell damage through its antioxidant activity.
In the long-term heavy metal model, curcumin inhibited the toxic effect caused by the accumulation of the metal in the induction of kidney cell damage.
In an animal model induced cisplatin-induced acute kidney injury by injection of cisplatin, curcumin enhanced the function of cisplatin-resistant cancer cells and decreased its unwanted side effects.
More interestingly, curcumin inhibited the nicotine receptors on kidney cells that link nicotine to accelerated kidney damage in cigarette smokers
In other words. if the kidneys are less able to excrete nicotine, in the long term, accumulated extracellular fluid and blood volumes increase, which can lead to severe kidney damage.
In other studies, kidney damage caused by maleate, malathion, nicotine, cisplatin, gentamicin, and methotrexate was also reversed by the injection of curcumin, similar to those of the aforementioned substances.
Taken altogether, turmeric and its bioactive compound curcumin may be considered remedies for the prevention and treatment of kidney damage, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis by Ramadan G1, El-Menshawy O. (PubMed)
(2) Protective effects of curcumin against toxic agents-induced renal failure: a review by Farkhondeh T1, Samarghandian S2, Azimi-Nezhad M2, Shahri AMP. (PubMed)
(3) High Blood Pressure and Chronic Kidney Disease by The Natural Kidney Foundation
#Herbal Chaste Tree Berry Improves Hormone Expression in Natural and d-Galactose-Induced Aging, Researchers Say
Kyle J. Norton
Chaste tree berries may have a strong effect in reducing the risk of free radical progression in inducing various diseases, the renowned institute suggested.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.
Antioxidants are chemical compounds with the function of inhibiting oxidation caused by the production of free radicals with an aim to reduce the risk of oxidative damage to our body.
According to the Faculty of Pharmacy, Ege University, in the observation of the chemical activity of different preparations of Chaste tree berry, researchers showed that water and ethanol extract content is far stronger antioxidant activity in compared to n-hexane extracts.
In vitro antioxidant assays, the newly differentiated ingredients isolated from the Chaste tree berry, EtOAc extract displayed a significant antioxidant property in reduced free radicals caused by brain homogenate. at the concentration-dependent effect tested by 1,1-diphenyl-2-picrylhydrasyl (DPPH) free radical assay (IC(50) = 68 microg/mL) in compared fractions of MeOH-H(2)O and n-hexane fraction.
The study also suggested that the efficacy of the antioxidant effect in the extract may have resulted from the recently discovered phytochemicals, flavonoid constituents EtOAc extract, capsaicin, vitexin, and orientin as viewed in the tested essay.
More importantly, in support of the above differentiation, a study of mice subcutaneously injected with d-galactose (500 mg/kg/d for 45 days) induced aging and natural aging. administrated extract of Vitex (600 mg/kg/bid for 7 days by gavage) to 72 female NMRI mice (48 3-month-old normal mice and 24 18-24-month-old mice), weighing 30-35 g randomly divided into six groups: control, Vitex, d-galactose, Vitex + d-galactose, Aging, and Vitex + Aging, groups treated with chaste tree berry expressed a superior effect in restored estrous cycle and damage of uterus and ovarian tissues, through antioxidant activities in ameliorated oxidative stress and aging diseases.
Truly, mice treated with extract of Chaste tree berry only showed a reduced presence of free radicals but also improved hormone expression in natural and d-galactose-induced aging.
Taking together, there is no doubt that Chaste tree berries display a significant antioxidant potential in ameliorating the risk of free radicals in induced chronic diseases, but a large amount of intake should be taken with care.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Antioxidant activity of Vitex agnus-castus L. extracts by Sağlam H1, Pabuçcuoğlu A, Kivçak B.(PubMed)
(2) Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents by Hajdú Z1, Hohmann J, Forgo P, Martinek T, Dervarics M, Zupkó I, Falkay G, Cossuta D, Máthé I.(PubMed)
(3) Effects of Vitex agnus-castus fruit on sex hormones and antioxidant indices in a d-galactose-induced aging female mouse model by Ahangarpour A1, Najimi SA2, Farbood Y3.(PubMed)
Chaste tree berries may have a strong effect in reducing the risk of free radical progression in inducing various diseases, the renowned institute suggested.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.
Antioxidants are chemical compounds with the function of inhibiting oxidation caused by the production of free radicals with an aim to reduce the risk of oxidative damage to our body.
According to the Faculty of Pharmacy, Ege University, in the observation of the chemical activity of different preparations of Chaste tree berry, researchers showed that water and ethanol extract content is far stronger antioxidant activity in compared to n-hexane extracts.
In vitro antioxidant assays, the newly differentiated ingredients isolated from the Chaste tree berry, EtOAc extract displayed a significant antioxidant property in reduced free radicals caused by brain homogenate. at the concentration-dependent effect tested by 1,1-diphenyl-2-picrylhydrasyl (DPPH) free radical assay (IC(50) = 68 microg/mL) in compared fractions of MeOH-H(2)O and n-hexane fraction.
The study also suggested that the efficacy of the antioxidant effect in the extract may have resulted from the recently discovered phytochemicals, flavonoid constituents EtOAc extract, capsaicin, vitexin, and orientin as viewed in the tested essay.
More importantly, in support of the above differentiation, a study of mice subcutaneously injected with d-galactose (500 mg/kg/d for 45 days) induced aging and natural aging. administrated extract of Vitex (600 mg/kg/bid for 7 days by gavage) to 72 female NMRI mice (48 3-month-old normal mice and 24 18-24-month-old mice), weighing 30-35 g randomly divided into six groups: control, Vitex, d-galactose, Vitex + d-galactose, Aging, and Vitex + Aging, groups treated with chaste tree berry expressed a superior effect in restored estrous cycle and damage of uterus and ovarian tissues, through antioxidant activities in ameliorated oxidative stress and aging diseases.
Truly, mice treated with extract of Chaste tree berry only showed a reduced presence of free radicals but also improved hormone expression in natural and d-galactose-induced aging.
Taking together, there is no doubt that Chaste tree berries display a significant antioxidant potential in ameliorating the risk of free radicals in induced chronic diseases, but a large amount of intake should be taken with care.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Antioxidant activity of Vitex agnus-castus L. extracts by Sağlam H1, Pabuçcuoğlu A, Kivçak B.(PubMed)
(2) Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents by Hajdú Z1, Hohmann J, Forgo P, Martinek T, Dervarics M, Zupkó I, Falkay G, Cossuta D, Máthé I.(PubMed)
(3) Effects of Vitex agnus-castus fruit on sex hormones and antioxidant indices in a d-galactose-induced aging female mouse model by Ahangarpour A1, Najimi SA2, Farbood Y3.(PubMed)
#Fennel Inhibits Ulcerogenic Expression through its Antioxidant Activities, Researchers Find
Kyle J. Norton
Fennel may have a therapeutic and enhanced effect in improving the digestive system in absorbing nutrients and fluids from food intake, some scientists suggested.
The result of this efficacy was published online by several respectable institutes, including the University of Illinois at Chicago and Afyon Kocatepe University.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the study, researchers set out criteria and guideline to investigate the effect of fennel in the gram-negative bacterium Helicobacter pylori (HP), the microorganisms have been associated with the development of gastritis and peptic ulcer disease to confirm the theory used in traditional medicine fennel to treat a wide range of ailments, including gastrointestinal (GI) disorders such as dyspepsia, gastritis and peptic ulcer disease (PUD), application of methanol extracts of botanicals with a MIC of 50 microg/mL included Achillea millefolium, Foeniculum vulgare (seed), exerted a significant inhibitory effect against all susceptibility of 15 HP strains.
These results suggested that injection of fennel displayed potential in balancing the ratio of microorganisms in the gastrointestinal tract, thus improve the function in absorbed and distributed nutrients to the body and reassured the herbal medicine used in practice for the treatment of numbers symptoms of
digestive disorder.
Furthermore, in an animal model with rat-induced gastric lesions by injection of ethanol, the application of aqueous extracts of Foeniculum vulgare (FVE) showed strong activity in inhibiting ulcerogenic expression through its antioxidant activities.
In observation of the efficacy of 60 minutes pre-administration of the doses of 75, 150, and 300 mg/kg, with famotidine, histamine H₂ receptor antagonist with function to inhibit stomach acid production, used at the dose of 20 mg/kg, before injection of ethanol, researchers found that
* Pre-treatment of all doses exerted a significant gastric protective effect in reduced injury and damage caused by the injection of ethanol.
* Fennel extract demonstrated a therapeutic activity linearly compared to other doses and control at a dose of 300 mg/kg
* These activities were associated with reducing malondialdehyde (MDA) levels, a marker in the expression of severe levels of oxidative stress.
Additional analysis, also suggested that fennel stimulated the gastro-protect effect through its antioxidants and facilitated the production of antioxidants found in the body tissues in inhibited the overexpression of free radicals, thus maintaining the ratio of microorganisms in the digestive tract and its functioning.
After, taking into account other co and confounders, researchers also suggested that the result in part may also attributed to antioxidants in ameliorated lipid peroxidation.
The above differentiation was supported by the joint report led by the Joint Keio University in the investigation of fennel properties associated with functional dyspepsia (FD), a functional gastrointestinal disorder characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain.
Truly, Delayed gastric emptying and impaired gastric accommodation was found to play important roles in the development of FD.
Anethole (1-methoxy-4-((E)-propenyl)-benzene), a major component of fennel essential oil, in rodents, exerted a huge effect in improved clonidine-induced delayed gastric emptying without harming normal gastric emptying in mice, orally.
Also, the application of fennel oil plus Anchu-san (a Japanese herbal medicine containing anethole) also demonstrated an important activity in reducing the risk of functional dyspepsia (FD) by restoring delayed gastric emptying.
In other words, anethole processes a gastroprotective efficacy through stimulating gastric accommodation.
Taken together, whole fennel, fennel essential oil, and its bioactive compound anethole may be used as a secondary application in reduced risk and treatment of digestive disorder. Adding a portion of fennel to your diet may improve the digestive function in the absorption of nutrients and fluids from the food intake.
However, intake of supplements should be taken with extreme care as an overdose may cause acute liver toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders by Mahady GB1, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR.(PubMed)
(2) Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats by Birdane FM1, Cemek M, Birdane YO, Gülçin I, Büyükokuroğlu ME.(PubMed)
(3) Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents by Asano T1, Aida S2, Suemasu S2, Mizushima T3.(PubMed)
Fennel may have a therapeutic and enhanced effect in improving the digestive system in absorbing nutrients and fluids from food intake, some scientists suggested.
The result of this efficacy was published online by several respectable institutes, including the University of Illinois at Chicago and Afyon Kocatepe University.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the study, researchers set out criteria and guideline to investigate the effect of fennel in the gram-negative bacterium Helicobacter pylori (HP), the microorganisms have been associated with the development of gastritis and peptic ulcer disease to confirm the theory used in traditional medicine fennel to treat a wide range of ailments, including gastrointestinal (GI) disorders such as dyspepsia, gastritis and peptic ulcer disease (PUD), application of methanol extracts of botanicals with a MIC of 50 microg/mL included Achillea millefolium, Foeniculum vulgare (seed), exerted a significant inhibitory effect against all susceptibility of 15 HP strains.
These results suggested that injection of fennel displayed potential in balancing the ratio of microorganisms in the gastrointestinal tract, thus improve the function in absorbed and distributed nutrients to the body and reassured the herbal medicine used in practice for the treatment of numbers symptoms of
digestive disorder.
Furthermore, in an animal model with rat-induced gastric lesions by injection of ethanol, the application of aqueous extracts of Foeniculum vulgare (FVE) showed strong activity in inhibiting ulcerogenic expression through its antioxidant activities.
In observation of the efficacy of 60 minutes pre-administration of the doses of 75, 150, and 300 mg/kg, with famotidine, histamine H₂ receptor antagonist with function to inhibit stomach acid production, used at the dose of 20 mg/kg, before injection of ethanol, researchers found that
* Pre-treatment of all doses exerted a significant gastric protective effect in reduced injury and damage caused by the injection of ethanol.
* Fennel extract demonstrated a therapeutic activity linearly compared to other doses and control at a dose of 300 mg/kg
* These activities were associated with reducing malondialdehyde (MDA) levels, a marker in the expression of severe levels of oxidative stress.
Additional analysis, also suggested that fennel stimulated the gastro-protect effect through its antioxidants and facilitated the production of antioxidants found in the body tissues in inhibited the overexpression of free radicals, thus maintaining the ratio of microorganisms in the digestive tract and its functioning.
After, taking into account other co and confounders, researchers also suggested that the result in part may also attributed to antioxidants in ameliorated lipid peroxidation.
The above differentiation was supported by the joint report led by the Joint Keio University in the investigation of fennel properties associated with functional dyspepsia (FD), a functional gastrointestinal disorder characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain.
Truly, Delayed gastric emptying and impaired gastric accommodation was found to play important roles in the development of FD.
Anethole (1-methoxy-4-((E)-propenyl)-benzene), a major component of fennel essential oil, in rodents, exerted a huge effect in improved clonidine-induced delayed gastric emptying without harming normal gastric emptying in mice, orally.
Also, the application of fennel oil plus Anchu-san (a Japanese herbal medicine containing anethole) also demonstrated an important activity in reducing the risk of functional dyspepsia (FD) by restoring delayed gastric emptying.
In other words, anethole processes a gastroprotective efficacy through stimulating gastric accommodation.
Taken together, whole fennel, fennel essential oil, and its bioactive compound anethole may be used as a secondary application in reduced risk and treatment of digestive disorder. Adding a portion of fennel to your diet may improve the digestive function in the absorption of nutrients and fluids from the food intake.
However, intake of supplements should be taken with extreme care as an overdose may cause acute liver toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders by Mahady GB1, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR.(PubMed)
(2) Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats by Birdane FM1, Cemek M, Birdane YO, Gülçin I, Büyükokuroğlu ME.(PubMed)
(3) Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents by Asano T1, Aida S2, Suemasu S2, Mizushima T3.(PubMed)
#Chaste Tree Berry Exerts a Significantly #Osteoprotective Activity, Scientists Say
Kyle J. Norton
Chaste tree berry is found to be processability in reduced MALE osteopenia turnover, the early sign of osteoporosis, a renowned institution study reported.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
In a total of 60, 3-month-old male rats orchidectomized and divided into five groups with each group either receiving soy-free food (C), estradiol (E), testosterone (T), or Vitex agnus castus in different concentrations (AC high/AC low) for 12 weeks, rats treated with Vitex agnus castus at highest dose displayed a recover of 88.4% of the trabecular bone area, 80.7% of the trabecular number and 66.9% of the number of trabecular nodes compared with other administrations.
The study also found out that Vitex agnus castus is more protective in treating osteoporosis in the male population compared female counterpart.
Dr. Sehmisch S, the lead author said, " Vitex agnus castus demonstrated osteoprotective effects in males. It preserves the cortical as well as the trabecular bone and might be a safe alternative for HRT".
Furthermore, In the study to compare a group of animals (n = 8) treated subcutaneously (s.c.) with 60 mg/kg of Vac essential oil once a day for 3 weeks and control animals (n = 8) received sterile olive oil s.c. by the same schedule, Vitex agnus-castus L. (Vac) essential oil-treated group also exerted a significant bone metabolism in 16-month-old male Wistar rats.
The osteoporosis protection can be observed through the lower Serum osteocalcin (OC) and calcium (Ca2+) in Vitex agnus-castus L. (Vac) essential oil and decreased bone turnover treated group in compared control in middle-aged male rats.
Taking together, Chaste tree berry showed strong support in the reduced early onset of osteoporosis of male gander through improved bone metabolism and calcium status, but further, large size and centers studies are necessary to validate this potency.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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Sources
(1) Vitex agnus castus as prophylaxis for osteopenia after orchidectomy in rats compared with estradiol and testosterone supplementation by Sehmisch S1, Boeckhoff J, Wille J, Seidlova-Wuttke D, Rack T, Tezval M, Wuttke W, Stuermer KM, Stuermer EK. (PubMed)
(2) Vitex agnus-castus essential oil affects thyroid C cells and bone metabolism in middle-aged male rats (Researchgate)
Chaste tree berry is found to be processability in reduced MALE osteopenia turnover, the early sign of osteoporosis, a renowned institution study reported.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
In a total of 60, 3-month-old male rats orchidectomized and divided into five groups with each group either receiving soy-free food (C), estradiol (E), testosterone (T), or Vitex agnus castus in different concentrations (AC high/AC low) for 12 weeks, rats treated with Vitex agnus castus at highest dose displayed a recover of 88.4% of the trabecular bone area, 80.7% of the trabecular number and 66.9% of the number of trabecular nodes compared with other administrations.
The study also found out that Vitex agnus castus is more protective in treating osteoporosis in the male population compared female counterpart.
Dr. Sehmisch S, the lead author said, " Vitex agnus castus demonstrated osteoprotective effects in males. It preserves the cortical as well as the trabecular bone and might be a safe alternative for HRT".
Furthermore, In the study to compare a group of animals (n = 8) treated subcutaneously (s.c.) with 60 mg/kg of Vac essential oil once a day for 3 weeks and control animals (n = 8) received sterile olive oil s.c. by the same schedule, Vitex agnus-castus L. (Vac) essential oil-treated group also exerted a significant bone metabolism in 16-month-old male Wistar rats.
The osteoporosis protection can be observed through the lower Serum osteocalcin (OC) and calcium (Ca2+) in Vitex agnus-castus L. (Vac) essential oil and decreased bone turnover treated group in compared control in middle-aged male rats.
Taking together, Chaste tree berry showed strong support in the reduced early onset of osteoporosis of male gander through improved bone metabolism and calcium status, but further, large size and centers studies are necessary to validate this potency.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Vitex agnus castus as prophylaxis for osteopenia after orchidectomy in rats compared with estradiol and testosterone supplementation by Sehmisch S1, Boeckhoff J, Wille J, Seidlova-Wuttke D, Rack T, Tezval M, Wuttke W, Stuermer KM, Stuermer EK. (PubMed)
(2) Vitex agnus-castus essential oil affects thyroid C cells and bone metabolism in middle-aged male rats (Researchgate)
#Diphenylhydantoin and #Valproicacid Isolated From Chaste Tree Berry Process Anticonvulsant Activity, Researchers Show
Kyle J. Norton
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.
In a study using an animal model of maximal electroshock seizures (MES) and induced seizures (MES) by administrated pentylenetetrazole (PTZ), intake of ethanolic leaf extract of Vitex-negundo, at doses of 250, 500, and 1000 mg/kg p.o, exerted a significant of postictal depression, an altered state of consciousness after an epileptic seizure in the dose of 1000 mg/kg body weight in comparison to control but no effects in other applications.
At doses of (1000 mg/kg, PO), the ethanolic leaf extract exhibited a 50% half-life protection in chronic seizures after a 24-hour injection against PTZ-induced seizures. Researchers also found that the efficacy of the extract at that dose is the result of valproic acid, a major ingredient found in Chaste tree berries.
Dr. Tandon VR and co-author Dr. Gupta RK. of the study said, " The anticonvulsant activity of Vitex-negundo has not been found quite effective with standard drugs".
Furthermore, because the potentiation of diphenylhydantoin and valproic acid isolated Vitex-negundo displayed a significant effect in treating animal models, the extract may be used as an adjuvant therapy along with standard anticonvulsants.
Additionally, according to the Baqiyatallah University of Medical Sciences, hydrophilic extract of Vitex agnus castus fruit (Vitex) administered doses (60, 120, or 180 mg/kg) showed a strong anticonvulsant activity even at low doses (60 mg/kg) of Vitex by increasing the afterdischarge(AD) threshold and decrease the afterdischarge duration ( ADD) and stage 5 duration (S5D).
Promisingly, at the highest dose, the extract inhibited significantly the seizure stage (P<0.01) and reduced or prevented epileptic activity as demonstrated by the reduction of ADD and S5D (length of convulsion) in a dose-dependent manner.
More importantly, methanolic extract (ME) of the leaves of V. negundo also showed to process the analgesic properties and potentiated analgesia demonstrated by morphine and pethidine in protection against strychnine and leptazole-induced convulsions.
Taking together, Chaste Tree Berry may be one of the next-generation therapeutic herbal medicines that have a strong effect on the prevention and treatment of seizures as a result of abundant phytochemicals, but intake of the large amount should be taken with care to reduce the risk of toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) An experimental evaluation of anticonvulsant activity of Vitex-negundo by Tandon VR1, Gupta RK.(PubMed)
(2) The antiepileptic activity of Vitex agnus castus extract on amygdala kindled seizures in male rats by Saberi M1, Rezvanizadeh A, Bakhtiarian A.(PubMed)
(2) CNS activity of Vitex negundo Linn. in mice by Gupta M1, Mazumder UK, Bhawal SR.(PubMed)
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.
In a study using an animal model of maximal electroshock seizures (MES) and induced seizures (MES) by administrated pentylenetetrazole (PTZ), intake of ethanolic leaf extract of Vitex-negundo, at doses of 250, 500, and 1000 mg/kg p.o, exerted a significant of postictal depression, an altered state of consciousness after an epileptic seizure in the dose of 1000 mg/kg body weight in comparison to control but no effects in other applications.
At doses of (1000 mg/kg, PO), the ethanolic leaf extract exhibited a 50% half-life protection in chronic seizures after a 24-hour injection against PTZ-induced seizures. Researchers also found that the efficacy of the extract at that dose is the result of valproic acid, a major ingredient found in Chaste tree berries.
Dr. Tandon VR and co-author Dr. Gupta RK. of the study said, " The anticonvulsant activity of Vitex-negundo has not been found quite effective with standard drugs".
Furthermore, because the potentiation of diphenylhydantoin and valproic acid isolated Vitex-negundo displayed a significant effect in treating animal models, the extract may be used as an adjuvant therapy along with standard anticonvulsants.
Additionally, according to the Baqiyatallah University of Medical Sciences, hydrophilic extract of Vitex agnus castus fruit (Vitex) administered doses (60, 120, or 180 mg/kg) showed a strong anticonvulsant activity even at low doses (60 mg/kg) of Vitex by increasing the afterdischarge(AD) threshold and decrease the afterdischarge duration ( ADD) and stage 5 duration (S5D).
Promisingly, at the highest dose, the extract inhibited significantly the seizure stage (P<0.01) and reduced or prevented epileptic activity as demonstrated by the reduction of ADD and S5D (length of convulsion) in a dose-dependent manner.
More importantly, methanolic extract (ME) of the leaves of V. negundo also showed to process the analgesic properties and potentiated analgesia demonstrated by morphine and pethidine in protection against strychnine and leptazole-induced convulsions.
Taking together, Chaste Tree Berry may be one of the next-generation therapeutic herbal medicines that have a strong effect on the prevention and treatment of seizures as a result of abundant phytochemicals, but intake of the large amount should be taken with care to reduce the risk of toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) An experimental evaluation of anticonvulsant activity of Vitex-negundo by Tandon VR1, Gupta RK.(PubMed)
(2) The antiepileptic activity of Vitex agnus castus extract on amygdala kindled seizures in male rats by Saberi M1, Rezvanizadeh A, Bakhtiarian A.(PubMed)
(2) CNS activity of Vitex negundo Linn. in mice by Gupta M1, Mazumder UK, Bhawal SR.(PubMed)
#Herbal #Angelica Improves #Hyperglycemia, Glucose Tolerance and Plasma Insulin Levels in #Diabetes in Vivos, Researchers Say
Kyle J. Norton
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability, and gastrointestinal symptoms such as nausea.
Some patients may also experience symptoms of blurred vision and slow wound healing or ulcer.
Prediabetes is caused by unhealthy diets with high saturated fat, smoking, and excessive alcohol drinking. Therefore, understanding prediabetes is a very important issue for prediabetics, because with proper diets, quit smoking, control alcohol intake, and exercises, prediabetes can be reversed or delayed.
People with a glucose level between 111mg/dl-125 mg/dl are considered pre-diabetics
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occur in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy).
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million who are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of foreign microorganisms and inhibits the overactive immune system that causes autoimmune diseases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
In finding an herbal medicine for the prevention and treatment of diabetes, researchers investigated the effects of the decoction HemoHIM on hyperglycemia and the immune response in diabetic mice.
Mice selected for the study were divided into nondiabetic and diabetic mice induced by a single injection of streptozotocin (STZ, 200 mg/kg, i.p.) orally administered HemoHIM (100 mg/kg) once a day for 4 weeks.
Diabetic mice with HemoHIM showed improved hyperglycemia and glucose tolerance as well as elevated plasma insulin levels with the preservation of insulin staining in pancreatic β-cells, compared to the diabetic control group.
Furthermore, HemoHIM treatment restored parameters associated with the onset of diabetes including thymus weight, white blood cells, lymphocyte numbers, and splenic lymphocyte populations (CD4(+) T and CD8(+) T), which were reduced in diabetic mice.
Moreover, HemoHIM also animalized the IFN-γ production associated with innate and adaptive immunity in response to Con A stimulation in facilitating mediated T cell proliferation.
Based on the results, researchers said, "HemoHIM may have potential as a glucose-lowering and immunomodulatory agent by enhancing the immune function of pancreatic β-cells in STZ-induced diabetic mice".
Taken altogether, Herbal Angelica is used in combination with other herbal medicines for the treatment of diabetes, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice by Kim JJ1, Choi J1, Lee MK2, Kang KY3, Paik MJ3, Jo SK4, Jung U4, Park HR4, Yee ST. (PubMed)
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability, and gastrointestinal symptoms such as nausea.
Some patients may also experience symptoms of blurred vision and slow wound healing or ulcer.
Prediabetes is caused by unhealthy diets with high saturated fat, smoking, and excessive alcohol drinking. Therefore, understanding prediabetes is a very important issue for prediabetics, because with proper diets, quit smoking, control alcohol intake, and exercises, prediabetes can be reversed or delayed.
People with a glucose level between 111mg/dl-125 mg/dl are considered pre-diabetics
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occur in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy).
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million who are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of foreign microorganisms and inhibits the overactive immune system that causes autoimmune diseases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
In finding an herbal medicine for the prevention and treatment of diabetes, researchers investigated the effects of the decoction HemoHIM on hyperglycemia and the immune response in diabetic mice.
Mice selected for the study were divided into nondiabetic and diabetic mice induced by a single injection of streptozotocin (STZ, 200 mg/kg, i.p.) orally administered HemoHIM (100 mg/kg) once a day for 4 weeks.
Diabetic mice with HemoHIM showed improved hyperglycemia and glucose tolerance as well as elevated plasma insulin levels with the preservation of insulin staining in pancreatic β-cells, compared to the diabetic control group.
Furthermore, HemoHIM treatment restored parameters associated with the onset of diabetes including thymus weight, white blood cells, lymphocyte numbers, and splenic lymphocyte populations (CD4(+) T and CD8(+) T), which were reduced in diabetic mice.
Moreover, HemoHIM also animalized the IFN-γ production associated with innate and adaptive immunity in response to Con A stimulation in facilitating mediated T cell proliferation.
Based on the results, researchers said, "HemoHIM may have potential as a glucose-lowering and immunomodulatory agent by enhancing the immune function of pancreatic β-cells in STZ-induced diabetic mice".
Taken altogether, Herbal Angelica is used in combination with other herbal medicines for the treatment of diabetes, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice by Kim JJ1, Choi J1, Lee MK2, Kang KY3, Paik MJ3, Jo SK4, Jung U4, Park HR4, Yee ST. (PubMed)
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