Kyle J. Norton
Triglycerides are accumulated in the blood for future use by converting any unused calories.
In other words, triglycerides are an ester derived from glycerol and three fatty acids (from tri- and glyceride).
Overexpression of hyperglyceridemia is found in patients with atherosclerosis even without the presence of high cholesterol levels, and predispose.
Hypertriglyceridemia is a condition characterized by high levels of triglycerides in the blood.
Hypertriglyceridemia can also accumulate in the arterial wall or combine with other substances to form plaque that narrows the arteries in transporting rich oxygenated blood to the heart and other parts of the body, leading to the onset of atherosclerosis.
Primary hypertriglyceridemia is found in 5% of patients associated with genetic preposition compared to 95% of secondary hypertriglyceridemia found in obese metabolic syndrome, diabetes,... patients.
Treating hypertriglyceridemia is difficult, as the condition frequently coexistence with other conditions that affect cardiovascular disease risks, such as high levels of low-density lipoprotein, obesity, metabolic syndrome, and type 2 diabetes.
In severe cases of hypertriglyceridemia, patients may also experience the complication of acute pancreatitis, independent of the risk of CVD.
On finding a potential whole food for the treatment of diabetes, researchers examined the effects of the once-daily intake of the green-plant membrane with dietary oil on postprandial hypertriglyceridemia in vitro and in vivo.
In vitro, green-plant membrane-bound hydrophobic bile acids but did not inhibit pancreatic lipase activity.
The green-plant membrane in rats, oral fat tolerance tests, and increased serum triglyceride levels were significantly reduced.
Moreover, fecal total lipid and bile acid volumes were significantly increased in rats that were administered 200 mg/mL green-plant membrane.
Based on the evidence, researchers said, "...green-plant membrane with dietary oil inhibits dietary fat absorption via promotion of bile acid excretion in feces and the effectiveness of eating green-plant membrane, such as green leafy vegetables, with meals".
Taken altogether, the green-plant membrane may be considered a functional food for the prevention of hypertriglyceridemia, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Intake of green-plant membrane with dietary oil suppresses postprandial hypertriglyceridemia in rats via promoting excretion of bile acids by Matsuda H1, Ooi S1, Otokozawa R1, Kumazaki K1, Udagawa E1, Asakura M1, Suzuki D1, Shirai T. (PubMed)
Tuesday, 5 September 2023
#Photocomposition (PC-1) Extract Processes a Strong Anti-Lipid Peroxidation (LPO)O and Antihemolytic Effect, Researchers Suggest
Kyle J. Norton
The liver is the largest internal and only organ in the human body that can regenerate itself.
The liver is the first line of detoxing defense by filtering the blood that comes from the digestive tract, before passing them to other organs and tissues in the body.
The liver also produces cholesterol that plays a critical role in building strong cell membranes, producing steroid hormones and vitamin D, and aiding the digestive function in food absorption and detoxifying chemicals and metabolizing drugs.
The hepatoprotective or liver protective effect is an action that maintains the healthy function of the liver against any harmful toxins.
Symptoms of liver diseases include jaundice, abdominal pain, swelling, swelling in the legs and ankles, itchy skin, dark urine, pale stool color, and a tendency to bruise easily.
There are no exact causes of liver disease. Viruses, toxins, genetics, alcohol, and unknown causes are some prevalent factors found in patients with chronic liver disease, including cancer.
In the US, most cases of liver disease are a result of hepatitis viral infection and autoimmune diseases. Infectious viral hepatitis can produce toxins to protect them against the antioxidant enzymes produced by the host body and prevent the attack of the systematic immune response.
Furthermore, in recent years, excessive alcohol drinking has been found to induce alcoholic liver disease in many parts of Asia and America.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used for thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches obstruction in the nasal passage, etc.
In finding a potential compound which processes a liver protective effect, researchers examined the highly active photocomposition (PC-1) containing oregano (Origanum vulgare), wild thyme (Thymus serpyllum) and coltsfoot (Tussilago farfara) aerial parts, valerian (Valeriana officinalis) leaves and little-leaf linden (Tilia cordata) flowers and PC-1 extract exhibited the strongest anti-lipid peroxidation (LPO)O and antihemolytic effects.
According to the tested results, PC-1 extract activated the Nrf2/antioxidant response is more effective compared to the extracts of other photocomposition.
Furthermore, oral administration of PC-1 extract (100-200 mg/kg) markedly protected the rat liver injury acutely or chronically against intoxication by carbon tetrachloride.
The liver protective activity of PC-1 was attributed to the activation of the levels of antioxidant enzymes in the host and the improvement of liver histology, blood chemistry parameters.
Moreover, the osmotic fragility test (OFT) also addressed that PC-1 extract inhibited the destruction of red blood cells in carbon tetrachloride intoxicated rats.
Based on the findings, researchers said, "These data support the strategy of in-vitro plant selection for developing efficacious tissue-protective photocomposition".
Taken together, coltsfoot may be considered a liver protective remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A composition of medicinal plants with an enhanced ability to suppress microsomal lipid peroxidation and a protective activity against carbon tetrachloride-induced hepatotoxicity by Aralbaeva AN1, Mamataeva AT1, Zhaparkulova NI2, Utegalieva RS1, Khanin M3, Danilenko M4, Murzakhmetova MK. (PubMed)
The liver is the largest internal and only organ in the human body that can regenerate itself.
The liver is the first line of detoxing defense by filtering the blood that comes from the digestive tract, before passing them to other organs and tissues in the body.
The liver also produces cholesterol that plays a critical role in building strong cell membranes, producing steroid hormones and vitamin D, and aiding the digestive function in food absorption and detoxifying chemicals and metabolizing drugs.
The hepatoprotective or liver protective effect is an action that maintains the healthy function of the liver against any harmful toxins.
Symptoms of liver diseases include jaundice, abdominal pain, swelling, swelling in the legs and ankles, itchy skin, dark urine, pale stool color, and a tendency to bruise easily.
There are no exact causes of liver disease. Viruses, toxins, genetics, alcohol, and unknown causes are some prevalent factors found in patients with chronic liver disease, including cancer.
In the US, most cases of liver disease are a result of hepatitis viral infection and autoimmune diseases. Infectious viral hepatitis can produce toxins to protect them against the antioxidant enzymes produced by the host body and prevent the attack of the systematic immune response.
Furthermore, in recent years, excessive alcohol drinking has been found to induce alcoholic liver disease in many parts of Asia and America.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used for thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches obstruction in the nasal passage, etc.
In finding a potential compound which processes a liver protective effect, researchers examined the highly active photocomposition (PC-1) containing oregano (Origanum vulgare), wild thyme (Thymus serpyllum) and coltsfoot (Tussilago farfara) aerial parts, valerian (Valeriana officinalis) leaves and little-leaf linden (Tilia cordata) flowers and PC-1 extract exhibited the strongest anti-lipid peroxidation (LPO)O and antihemolytic effects.
According to the tested results, PC-1 extract activated the Nrf2/antioxidant response is more effective compared to the extracts of other photocomposition.
Furthermore, oral administration of PC-1 extract (100-200 mg/kg) markedly protected the rat liver injury acutely or chronically against intoxication by carbon tetrachloride.
The liver protective activity of PC-1 was attributed to the activation of the levels of antioxidant enzymes in the host and the improvement of liver histology, blood chemistry parameters.
Moreover, the osmotic fragility test (OFT) also addressed that PC-1 extract inhibited the destruction of red blood cells in carbon tetrachloride intoxicated rats.
Based on the findings, researchers said, "These data support the strategy of in-vitro plant selection for developing efficacious tissue-protective photocomposition".
Taken together, coltsfoot may be considered a liver protective remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A composition of medicinal plants with an enhanced ability to suppress microsomal lipid peroxidation and a protective activity against carbon tetrachloride-induced hepatotoxicity by Aralbaeva AN1, Mamataeva AT1, Zhaparkulova NI2, Utegalieva RS1, Khanin M3, Danilenko M4, Murzakhmetova MK. (PubMed)
#Phytochemical I3C and 3,3'-#Diindolylmethane Process Anti-Proliferative and #Anticancer Activities, Scientists Say
Kyle J. Norton
3,3'-Diindolylmethane or DIM may have a p[otential effect on the treatment of cancer with no side effects, according to studies.
Cancer is a group of diseases characterized by the cell growth uncontrollably in the tissue of certain organs, due to the alternation of cell DNA.
Epidemiologically, researchers do not the exact causes of cancer. They cannot explain why people with the same health conditions in the same family, are prone to the disease while others do not.
Most cases of cancer start in the cells on the surface of the inner lining tissue of an organ and at the advanced stage, cancer cells can travel a distance away from the original site to infect other tissues and organs through the circulation of blood and fluids, leading to secondary metastasis.
Cancer diagnosed at the early stage can have a survival rate of up to 100%, depending on the type of cancer.
All cancers share the general symptoms of unintended weight loss, loss of appetite, fatigue, tiredness, and gastrointestinal discomfort.
Furthermore, most cancers at the early stage do not induce any symptoms, however, at the later stage, the overgrowth tumor may press on the nearby blood vessels and nerve cells, leading to severe bleeding and pain.
Although there are several risk factors associated with the onset of cancer, some researchers suggest the increase in aging that leads to a number of abnormal alternations may be one of the major causes.
Dr. Jan R. Aunan, the lead scientist wrote in the study of the biological role of age and cancer, "Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development".
And, "Mechanisms of aging are also found to occur in carcinogenesis, albeit with shared or divergent end-results. It is now clear that aging and cancer development either share or diverge in several disease mechanisms. Such mechanisms include the role of genomic instability, telomere attrition, epigenetic changes, loss of proteostasis, decreased nutrient sensing and altered metabolism, but also cellular senescence and stem cell function".
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
Scientists concerned about the side effects of chemotherapy for the treatment of cancer examined the effects of I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) anti-proliferative and anticancer activities against human cancer cells.
Application of I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) exerted a strong activity in the inhibition of altered expression and exhibition of the functions of proteins associated with cell cycle arrest.
I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) deactivated the signal transduction pathways in the stimulation of cancer cell growth.
Furthermore, the phytochemicals suppressed the genes associated with cancer cell survival and proliferation and the protein involved in the generation of new blood vessels for the tumor.
Furthermore, the tested bioactive compound also activated the protein associated with the pro-apoptosis against the gene involved in anti-apoptosis of the cancer cells.
Additionally, I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) also overexpressed the gene involved in cell cycle arrest against the progression of cancer.
Dr.Noroozi MK and colleagues wrote at the end of the experiment, "I3C and its dimeric product, 3, 3'-diindolylmethane (DIM), have been widely investigated for their importance against a number of human cancers both in vitro and in vivo".
In the microRNA-21 analysis, researchers found that DIM inhibits the microRNA (miRNAs) expression against colon cancer (CAC) pathogenesis.
MicroRNAs (miRNAs) are a class of small noncoding RNAs of ∼22nt in length involved in the regulation of gene expression including inflammation and angiogenesis.
In mesothelioma, injection of DIM exerted anti-mesothelioma potentials, by lowering the expression of microRNA regulatory activities by suppressing macrophage infiltration and pro-inflammatory cytokines.
In other words, DIM modulated the immune response against the onset and progression of mesothelioma in stimulating the production of oxidative stress due to the overexpression of inflammatory cytokines in the initiation of the disease.
Taken altogether, DIM may be considered a supplement for the prevention and combined with primary medicine for the treatment of cancer, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Molecular targets, anti-cancer properties, and potency of synthetic indole-3-carbinol derivatives by Noroozi MK1, Mahmoodi M1, Jafarzadeh A1, Darekordi A2, Hajizadeh MR1, Hassanshahi G. (PubMed)
(2) Enhancing miR-132 expression by aryl hydrocarbon receptor attenuates tumorigenesis associated with chronic colitis by Alzahrani AM1, Hanieh H2, Ibrahim HM2, Mohafez O3, Shehata T4, Bani Ismail M2, Alfwuaires M. (PubMed)
(3) The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks by Jan R. Aunan,1,2,* William C Cho,3 and Kjetil Søreide. (PubMed)
3,3'-Diindolylmethane or DIM may have a p[otential effect on the treatment of cancer with no side effects, according to studies.
Cancer is a group of diseases characterized by the cell growth uncontrollably in the tissue of certain organs, due to the alternation of cell DNA.
Epidemiologically, researchers do not the exact causes of cancer. They cannot explain why people with the same health conditions in the same family, are prone to the disease while others do not.
Most cases of cancer start in the cells on the surface of the inner lining tissue of an organ and at the advanced stage, cancer cells can travel a distance away from the original site to infect other tissues and organs through the circulation of blood and fluids, leading to secondary metastasis.
Cancer diagnosed at the early stage can have a survival rate of up to 100%, depending on the type of cancer.
All cancers share the general symptoms of unintended weight loss, loss of appetite, fatigue, tiredness, and gastrointestinal discomfort.
Furthermore, most cancers at the early stage do not induce any symptoms, however, at the later stage, the overgrowth tumor may press on the nearby blood vessels and nerve cells, leading to severe bleeding and pain.
Although there are several risk factors associated with the onset of cancer, some researchers suggest the increase in aging that leads to a number of abnormal alternations may be one of the major causes.
Dr. Jan R. Aunan, the lead scientist wrote in the study of the biological role of age and cancer, "Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development".
And, "Mechanisms of aging are also found to occur in carcinogenesis, albeit with shared or divergent end-results. It is now clear that aging and cancer development either share or diverge in several disease mechanisms. Such mechanisms include the role of genomic instability, telomere attrition, epigenetic changes, loss of proteostasis, decreased nutrient sensing and altered metabolism, but also cellular senescence and stem cell function".
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
Scientists concerned about the side effects of chemotherapy for the treatment of cancer examined the effects of I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) anti-proliferative and anticancer activities against human cancer cells.
Application of I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) exerted a strong activity in the inhibition of altered expression and exhibition of the functions of proteins associated with cell cycle arrest.
I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) deactivated the signal transduction pathways in the stimulation of cancer cell growth.
Furthermore, the phytochemicals suppressed the genes associated with cancer cell survival and proliferation and the protein involved in the generation of new blood vessels for the tumor.
Furthermore, the tested bioactive compound also activated the protein associated with the pro-apoptosis against the gene involved in anti-apoptosis of the cancer cells.
Additionally, I3C and its dimeric product, 3, 3'-diindolylmethane (DIM) also overexpressed the gene involved in cell cycle arrest against the progression of cancer.
Dr.Noroozi MK and colleagues wrote at the end of the experiment, "I3C and its dimeric product, 3, 3'-diindolylmethane (DIM), have been widely investigated for their importance against a number of human cancers both in vitro and in vivo".
In the microRNA-21 analysis, researchers found that DIM inhibits the microRNA (miRNAs) expression against colon cancer (CAC) pathogenesis.
MicroRNAs (miRNAs) are a class of small noncoding RNAs of ∼22nt in length involved in the regulation of gene expression including inflammation and angiogenesis.
In mesothelioma, injection of DIM exerted anti-mesothelioma potentials, by lowering the expression of microRNA regulatory activities by suppressing macrophage infiltration and pro-inflammatory cytokines.
In other words, DIM modulated the immune response against the onset and progression of mesothelioma in stimulating the production of oxidative stress due to the overexpression of inflammatory cytokines in the initiation of the disease.
Taken altogether, DIM may be considered a supplement for the prevention and combined with primary medicine for the treatment of cancer, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Molecular targets, anti-cancer properties, and potency of synthetic indole-3-carbinol derivatives by Noroozi MK1, Mahmoodi M1, Jafarzadeh A1, Darekordi A2, Hajizadeh MR1, Hassanshahi G. (PubMed)
(2) Enhancing miR-132 expression by aryl hydrocarbon receptor attenuates tumorigenesis associated with chronic colitis by Alzahrani AM1, Hanieh H2, Ibrahim HM2, Mohafez O3, Shehata T4, Bani Ismail M2, Alfwuaires M. (PubMed)
(3) The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks by Jan R. Aunan,1,2,* William C Cho,3 and Kjetil Søreide. (PubMed)
#Phytochemical #Alliin Inhibits Metabolic Syndrome Against the Risk of #Cardiovasculardisease
Kyle J. Norton
Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular disease and diabetes, including too much fat around the waist, high blood pressure, triglycerides, and blood sugar, and low HDL cholesterol.
In other words, if you process 3 of the aforementioned conditions, you are at a higher risk of heart disease, stroke, and diabetes. However, most people with metabolic syndrome have never developed
CVD and diabetes.
Other than high blood glucose, induced thirst and urination, fatigue, and blurred vision, most patients with other metabolic conditions are asymptomatic.
Epidemiologically, aging, ethnicity, obesity, medical conditions such as diabetes, nonalcoholic fatty liver disease, and polycystic ovary syndrome are the most common risk factors found in patients with the syndrome.
Some researchers suggested that the promotion of the Western diet in the US over the past few decades may have a strong effect in inducing the widespread metabolic syndrome.
Dr. Drake I, the lead scientist wrote, "The 'Western' dietary pattern was inversely associated with HDL-cholesterol and positively with all other response variables (both at baseline and follow-up), but there was no association with LDL at follow-up".
And, " In conclusion, this study supports current food-based dietary guidelines suggesting that a 'Western' dietary pattern with high intakes of sugar-sweetened beverages and red and processed meats and low intakes of wine, cheese, vegetables, and high-fiber foods is associated with detrimental effects on cardio-metabolic health".
The results clearly suggested that if you are following a traditional diet with high fruits and vegetables and fewer processed foods, saturated and trans fat, and red meat accompanied with moderate exercise daily, you are at substantially decreased risk of metabolic syndrome, compared to those who follow the Western diet.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
In the urgency to find a potential compound for the treatment of metabolic syndrome, researchers examined pure allicin, prepared biosynthetically by reacting synthetic alliin with an immobilized alliinase enzyme the protect against cardiovascular disease.
S-ally-mercapto captopril (CPSSA), a new stable synthetic compound produced by a chemical reaction between allicin and the angiotensin-converting enzyme inhibitor captopril was tested in a fructose-induced metabolic syndrome rat model.
Allicin (8 mg/(kg day)) used alone significantly reduced insulin, triglycerides, and homocysteine concentrations, and had a slight effect on SBP associated with the risk of metabolic syndrome.
On the other hand, Captopril (50mg/(kg per day)) only improved blood pressure and homocysteine.
Treatment with a low dose of CPSSA (5mg/(kg day)) lowered SBP but did not improve any other measured parameter, while treatment with a higher dose of Captopril (50mg/(kg day)) significantly decreased blood pressure, triglycerides, and homocysteine concentrations.
In other words, CPSSA exerted a strong anti-metabolic syndrome better than those of individual compounds in a dose-dependent manner.
Based on the findings, researchers wrote, " the combined molecule CPSSA integrates the anti-hypertensive, lipid-lowering, and homocysteine-reducing effects of both allicin and captopril, making it a potential cardiovascular protective agent".
Taken together, alliin may be considered a supplement for the prevention and treatment of metabolic syndrome, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of S-ally-mercapto captopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome by Oron-Herman M1, Rosenthal T, Mirelman D, Miron T, Rabinkov A, Wilchek M, Sela BA. (PubMed)
(2) Role of phytochemicals in the management of metabolic syndrome by Cicero AF1, Colletti A. (PubMed)
(3) A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome by Drake I1, Sonestedt E1, Ericson U1, Wallström P2, Orho-Melander M. (PubMed)
Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular disease and diabetes, including too much fat around the waist, high blood pressure, triglycerides, and blood sugar, and low HDL cholesterol.
In other words, if you process 3 of the aforementioned conditions, you are at a higher risk of heart disease, stroke, and diabetes. However, most people with metabolic syndrome have never developed
CVD and diabetes.
Other than high blood glucose, induced thirst and urination, fatigue, and blurred vision, most patients with other metabolic conditions are asymptomatic.
Epidemiologically, aging, ethnicity, obesity, medical conditions such as diabetes, nonalcoholic fatty liver disease, and polycystic ovary syndrome are the most common risk factors found in patients with the syndrome.
Some researchers suggested that the promotion of the Western diet in the US over the past few decades may have a strong effect in inducing the widespread metabolic syndrome.
Dr. Drake I, the lead scientist wrote, "The 'Western' dietary pattern was inversely associated with HDL-cholesterol and positively with all other response variables (both at baseline and follow-up), but there was no association with LDL at follow-up".
And, " In conclusion, this study supports current food-based dietary guidelines suggesting that a 'Western' dietary pattern with high intakes of sugar-sweetened beverages and red and processed meats and low intakes of wine, cheese, vegetables, and high-fiber foods is associated with detrimental effects on cardio-metabolic health".
The results clearly suggested that if you are following a traditional diet with high fruits and vegetables and fewer processed foods, saturated and trans fat, and red meat accompanied with moderate exercise daily, you are at substantially decreased risk of metabolic syndrome, compared to those who follow the Western diet.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
In the urgency to find a potential compound for the treatment of metabolic syndrome, researchers examined pure allicin, prepared biosynthetically by reacting synthetic alliin with an immobilized alliinase enzyme the protect against cardiovascular disease.
S-ally-mercapto captopril (CPSSA), a new stable synthetic compound produced by a chemical reaction between allicin and the angiotensin-converting enzyme inhibitor captopril was tested in a fructose-induced metabolic syndrome rat model.
Allicin (8 mg/(kg day)) used alone significantly reduced insulin, triglycerides, and homocysteine concentrations, and had a slight effect on SBP associated with the risk of metabolic syndrome.
On the other hand, Captopril (50mg/(kg per day)) only improved blood pressure and homocysteine.
Treatment with a low dose of CPSSA (5mg/(kg day)) lowered SBP but did not improve any other measured parameter, while treatment with a higher dose of Captopril (50mg/(kg day)) significantly decreased blood pressure, triglycerides, and homocysteine concentrations.
In other words, CPSSA exerted a strong anti-metabolic syndrome better than those of individual compounds in a dose-dependent manner.
Based on the findings, researchers wrote, " the combined molecule CPSSA integrates the anti-hypertensive, lipid-lowering, and homocysteine-reducing effects of both allicin and captopril, making it a potential cardiovascular protective agent".
Taken together, alliin may be considered a supplement for the prevention and treatment of metabolic syndrome, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of S-ally-mercapto captopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome by Oron-Herman M1, Rosenthal T, Mirelman D, Miron T, Rabinkov A, Wilchek M, Sela BA. (PubMed)
(2) Role of phytochemicals in the management of metabolic syndrome by Cicero AF1, Colletti A. (PubMed)
(3) A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome by Drake I1, Sonestedt E1, Ericson U1, Wallström P2, Orho-Melander M. (PubMed)
#Phytochemical #Lycopene Is Inversely Associated with the Risk of HIV Injecting Drug Users (IDUs), Researchers Say
Kyle J. Norton
Infection is a condition that causes the invasion of stimuli and micropathogens, including viral infection.
A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.
Anti-viral effects are an act in which certain substances are used to cause the destruction of a virus.
In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells.
The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.
The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, attacks the white blood cells of the immune system,
The viral infection has been known to carry over some different stages, after successfully attaching to the host cell, the virus releases its mRNA into the host cell, leading to the recruitment of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.
The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.
However, if the immune system can not kill off the invaders within 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.
HIV infection left untreated will weaken the host immune system, leading to AIDs, a major cause of life-threatening infections and disease.
According to the statistics from the US government, approximately 1.1 million people in the U.S. are living with HIV today. About 15 percent of them (1 in 7) are unaware they are infected. In approximately38,700 Americans were newly infected with HIV.
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas.
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of cardiovascular diseases (HIV), researchers examined the serum antioxidant levels in 175 HIV-positive and 210 HIV-negative injecting drug users (IDUs) in Baltimore, Maryland.
According to the results of data collection of 30 HIV-positive IDUs who were receiving antiretroviral therapies (ART), mean serum levels of lycopene and lutein/zeaxanthin were significantly lower in HIV-positive IDUs than in HIV-negative IDUs.
In other words, lycopene and lutein/zeaxanthin an inversely associated with the risk of HIV injecting drug users (IDUs).
Furthermore, serum alpha-tocopherol levels were significantly higher in HIV-positive IDUs than HIV-negative IDUs (medians = 744 microg/dl and 718 microg/dl, respectively; p = 04).
Levels of antioxidant levels by ART regimen are lower among HIV-positive study subjects, comapred to the HIV-negative group.
After adjusting to other factors such as injecting drug use, dietary intake, supplement intake, gender, and alcohol intake, levels of alpha-tocopherol, beta-carotene, and beta-cryptoxanthin significant overall differences by ART regimen.
The protease inhibitor (PI) treatment group showed significant levels of three antioxidants comapred to the other three ART groups combined.
In other words, the protease inhibitor (PI) blocked the HIV replication for the production of infectious viral particles by exerting a significant antioxidant effect against oxidative stress levels in HIV-positive IDUs.
Based on the findings, researchers said, "circulating levels of lycopene, a biomarker of tomato-rich food, may play a role in early stages of atherogenesis and may have clinical and public health relevance".
Taken altogether, lycopene found in tomatoes combined with conventional medicine may be considered supplements for the prevention and treatment of HIV infection, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The potential role of lycopene for human health by Gerster H. (PubMed)
(2) Improved antioxidant status among HIV-infected injecting drug users on potent antiretroviral therapy by Tang AM1, Smit E, Semba RD, Shah N, Lyles CM, Li D, Vlahov D. (PubMed)
Infection is a condition that causes the invasion of stimuli and micropathogens, including viral infection.
A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.
Anti-viral effects are an act in which certain substances are used to cause the destruction of a virus.
In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells.
The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.
The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, attacks the white blood cells of the immune system,
The viral infection has been known to carry over some different stages, after successfully attaching to the host cell, the virus releases its mRNA into the host cell, leading to the recruitment of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.
The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.
However, if the immune system can not kill off the invaders within 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.
HIV infection left untreated will weaken the host immune system, leading to AIDs, a major cause of life-threatening infections and disease.
According to the statistics from the US government, approximately 1.1 million people in the U.S. are living with HIV today. About 15 percent of them (1 in 7) are unaware they are infected. In approximately38,700 Americans were newly infected with HIV.
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas.
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of cardiovascular diseases (HIV), researchers examined the serum antioxidant levels in 175 HIV-positive and 210 HIV-negative injecting drug users (IDUs) in Baltimore, Maryland.
According to the results of data collection of 30 HIV-positive IDUs who were receiving antiretroviral therapies (ART), mean serum levels of lycopene and lutein/zeaxanthin were significantly lower in HIV-positive IDUs than in HIV-negative IDUs.
In other words, lycopene and lutein/zeaxanthin an inversely associated with the risk of HIV injecting drug users (IDUs).
Furthermore, serum alpha-tocopherol levels were significantly higher in HIV-positive IDUs than HIV-negative IDUs (medians = 744 microg/dl and 718 microg/dl, respectively; p = 04).
Levels of antioxidant levels by ART regimen are lower among HIV-positive study subjects, comapred to the HIV-negative group.
After adjusting to other factors such as injecting drug use, dietary intake, supplement intake, gender, and alcohol intake, levels of alpha-tocopherol, beta-carotene, and beta-cryptoxanthin significant overall differences by ART regimen.
The protease inhibitor (PI) treatment group showed significant levels of three antioxidants comapred to the other three ART groups combined.
In other words, the protease inhibitor (PI) blocked the HIV replication for the production of infectious viral particles by exerting a significant antioxidant effect against oxidative stress levels in HIV-positive IDUs.
Based on the findings, researchers said, "circulating levels of lycopene, a biomarker of tomato-rich food, may play a role in early stages of atherogenesis and may have clinical and public health relevance".
Taken altogether, lycopene found in tomatoes combined with conventional medicine may be considered supplements for the prevention and treatment of HIV infection, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The potential role of lycopene for human health by Gerster H. (PubMed)
(2) Improved antioxidant status among HIV-infected injecting drug users on potent antiretroviral therapy by Tang AM1, Smit E, Semba RD, Shah N, Lyles CM, Li D, Vlahov D. (PubMed)
#BrassicaOleraceaVegetablesJuices Inhibit the Onset of Breast Cancer through Its Anti-Proliferative Activity, Researchers Say
Kyle J. Norton
Cancer is a class of diseases in which a group of cells grow and multiply disorderly and uncontrollably in our body.
The prevalence of breast cancer has been acknowledged in the scientific community worldwide. Breast cancer widespread in women in Southeast Asia as a result of over 2 decades of economic prosperity caused by an unhealthy diet is a major concern.
The women's breasts are made up of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of a woman's breast is totally determined by the amount of fat.
Breast cancer is a medical condition characterized by cell growth irregularly and disorderly in the breast tissue.
Most cases of breast cancer start in the cells on the surface of the inner lining of the breast tissue before spreading into deeper layers of the breast.
Breast cancer is first noticed as a painless lump in the breast or armpit and is most often discovered by the women themselves.
Breast skin irritation or dimpling, nipple pain, nipple retraction (turning inward), redness, and scaliness that cannot be healed within 3 weeks are also the signs and symptoms of breast cancer.
According to statistics, the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
People who inherited the genetic preposition of BRCA1 and 2 are associated with over 60% of the risk of breast cancer.
However, an unhealthy diet and lifestyle are some of the preventable risk factors that form a major cause of breast cancer onset.
In postmenopause, weight control is the major factor throughout life that appears to prevent breast cancer after menopause.
Daily physical activity and reduced intake of alcohol throughout life are associated with reduced risk of developing pre- and postmenopausal breast cancer, however, smoking during adolescence or early adulthood increases later risk of breast cancer.
Interestingly, in the depth discussion of the diet pattern in the risk of breast cancer, researchers do not find a direct link to breast cancer risk.
These results suggested by actively following a healthy lifestyle and moderate exercise, the risk of breast cancer can be decreased substantially.
Kale is a species of Brassica Oleracea, belonging to the family Brassicaceae, native to coastal southern and western Europe. The veggie leaf is highly nutritious and cultivated as a food in most parts of Europe.
In finding a potent compound for the prevention and treatment of cancers, researchers examined the antiproliferative activity of juice obtained from leaves of several varieties of Brassica oleracea on both estrogen receptor (ER)-positive (ER+; MCF-7 and BT474) and ER-negative (ER-; MDA-MB-231 and BT20) human breast cancer cell lines.
At low concentrations to a final concentration 5-15 mL/L,
* All cauliflower varieties tested suppressed cell proliferation in a dose-dependent manner.
* Although no evidence of apoptosis was found, cancer cell growth inhibition was accompanied by significant cell death at the higher juice concentrations.
* All juices showed a preference in the inhibition of breast cancer cells compared with other mammalian cell lines, such as ECV304, VERO, Hep2, 3T3, and MCF-10A.
In the cell levels, all juices exerted the inhibition of proliferation associated with significantly reduced CDK6 expression, and an increased level of p27 involved cell division and cell cycle arrest, respectively, in ER+ cells but not in ER- cells.
Based on the results, researchers said, "the edible part of Brassica oleracea contains substances that can markedly inhibit the growth of both ER+ and ER- human breast cancer cells, although through different mechanisms".
Taken together, kale, a member of cruciferous vegetables may be considered a functional food for the treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Mechanisms of action and antiproliferative properties of Brassica oleracea juice in human breast cancer cell lines by Brandi G1, Schiavano GF, Zaffaroni N, De Marco C, Paiardini M, Cervasi B, Magnani M. (PubMed)
Cancer is a class of diseases in which a group of cells grow and multiply disorderly and uncontrollably in our body.
The prevalence of breast cancer has been acknowledged in the scientific community worldwide. Breast cancer widespread in women in Southeast Asia as a result of over 2 decades of economic prosperity caused by an unhealthy diet is a major concern.
The women's breasts are made up of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of a woman's breast is totally determined by the amount of fat.
Breast cancer is a medical condition characterized by cell growth irregularly and disorderly in the breast tissue.
Most cases of breast cancer start in the cells on the surface of the inner lining of the breast tissue before spreading into deeper layers of the breast.
Breast cancer is first noticed as a painless lump in the breast or armpit and is most often discovered by the women themselves.
Breast skin irritation or dimpling, nipple pain, nipple retraction (turning inward), redness, and scaliness that cannot be healed within 3 weeks are also the signs and symptoms of breast cancer.
According to statistics, the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
People who inherited the genetic preposition of BRCA1 and 2 are associated with over 60% of the risk of breast cancer.
However, an unhealthy diet and lifestyle are some of the preventable risk factors that form a major cause of breast cancer onset.
In postmenopause, weight control is the major factor throughout life that appears to prevent breast cancer after menopause.
Daily physical activity and reduced intake of alcohol throughout life are associated with reduced risk of developing pre- and postmenopausal breast cancer, however, smoking during adolescence or early adulthood increases later risk of breast cancer.
Interestingly, in the depth discussion of the diet pattern in the risk of breast cancer, researchers do not find a direct link to breast cancer risk.
These results suggested by actively following a healthy lifestyle and moderate exercise, the risk of breast cancer can be decreased substantially.
Kale is a species of Brassica Oleracea, belonging to the family Brassicaceae, native to coastal southern and western Europe. The veggie leaf is highly nutritious and cultivated as a food in most parts of Europe.
In finding a potent compound for the prevention and treatment of cancers, researchers examined the antiproliferative activity of juice obtained from leaves of several varieties of Brassica oleracea on both estrogen receptor (ER)-positive (ER+; MCF-7 and BT474) and ER-negative (ER-; MDA-MB-231 and BT20) human breast cancer cell lines.
At low concentrations to a final concentration 5-15 mL/L,
* All cauliflower varieties tested suppressed cell proliferation in a dose-dependent manner.
* Although no evidence of apoptosis was found, cancer cell growth inhibition was accompanied by significant cell death at the higher juice concentrations.
* All juices showed a preference in the inhibition of breast cancer cells compared with other mammalian cell lines, such as ECV304, VERO, Hep2, 3T3, and MCF-10A.
In the cell levels, all juices exerted the inhibition of proliferation associated with significantly reduced CDK6 expression, and an increased level of p27 involved cell division and cell cycle arrest, respectively, in ER+ cells but not in ER- cells.
Based on the results, researchers said, "the edible part of Brassica oleracea contains substances that can markedly inhibit the growth of both ER+ and ER- human breast cancer cells, although through different mechanisms".
Taken together, kale, a member of cruciferous vegetables may be considered a functional food for the treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Mechanisms of action and antiproliferative properties of Brassica oleracea juice in human breast cancer cell lines by Brandi G1, Schiavano GF, Zaffaroni N, De Marco C, Paiardini M, Cervasi B, Magnani M. (PubMed)
#Phytochemical #Betanin Inhibits the Risk of Acute Kidney Injury Associated with Overexpression of Oxidativestress, Scientists Suggest
Kyle J. Norton
Acute inflammation is a condition that lasts in the short term caused by an immune system response to the injury.
Symptoms of pain, redness, immobility (loss of function), swelling, and heat may occur within minutes or hours, depending on the size and penetration of the wound.
Overproduction of proinflammatory cytokines induced by the immune response may cause damage or death of nearby healthy cells, leading to the formation of scars.
The symptoms may disappear sooner in people with a stronger immune system compared to the elderly and the wound is covered quickly in a few days.
However, if the wound is quite large, then some stitches may be needed and the wound recovery will go through 4 overlapped stages, including
* The stage of hemostasis is the process of the wound being closed by clotting.
* The second stage is involved in the production of inflammatory cytokines in the prevention of infection.
* The third stage is proliferation in which the wound is rebuilt with new tissues made up of collagen and extracellular matrix.
and
* The masturbating stage in which collagens are converted, the recovery is completed, and the wound is fully closed.
Any interruption of the overlapped stage may induce the formation of scars similar to those of overproduction of inflammatory cytokines.
Unfortunately, if the immune system can not kill off all invaders over a short period of time normally between 3 to 8 weeks, it will compromise, leading to chronic inflammation in facilitating several chronic diseases such as cardiovascular disease and diabetes.
Betanin is phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to discover a potential ingredient for the treatment of diseases associated with inflammation, researchers investigated the effects of the natural pigment betanin on oxidative stress and inflammation in the kidneys of paraquat-treated rats.
Selected rats were injected with Paraquat intraperitoneally to induce renal damage, then randomly divided into four groups: a control group, a paraquat group, and two paraquat groups that were treated with betanin at 25 and 100 mg/kg/d three days before and two days after paraquat administration.
Betanin treated group showed a significant effect in alleviating the paraquat-incurred acute kidney injury, evidenced by histological improvement, reducing serum and urine markers for kidney injury compared to the untreated group.
The bioactive compound also attenuated the inflammation induced by the injection of Paraquat observed by the reduced expression of inflammatory proteins.
Furthermore, betanin also inhibits the kidney's oxidative stress through its antioxidant activity.
Based on the findings, researchers said, "betanin may have a protective effect against paraquat-induced acute kidney damage. The mechanisms of the protection appear to be the inhibition of oxidative stress and inflammation".
Taken altogether, betanin may be considered a supplement for the prevention and treatment of diseases associated with inflammation, pending the confirmation of a larger sample size and multicenter human study.
Intake of betanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betanin attenuates oxidative stress and inflammatory reaction in kidneys of paraquat-treated rats by Tan D1, Wang Y2, Bai B1, Yang X2, Han J. (PubMed)
(2) Mechanism of interaction of betanin and indicaxanthin with human myeloperoxidase and hypochlorous acid by Allegra M1, Furtmüller PG, Jantschko W, Zederbauer M, Tesoriere L, Livrea MA, Obinger C. (PubMed)
Acute inflammation is a condition that lasts in the short term caused by an immune system response to the injury.
Symptoms of pain, redness, immobility (loss of function), swelling, and heat may occur within minutes or hours, depending on the size and penetration of the wound.
Overproduction of proinflammatory cytokines induced by the immune response may cause damage or death of nearby healthy cells, leading to the formation of scars.
The symptoms may disappear sooner in people with a stronger immune system compared to the elderly and the wound is covered quickly in a few days.
However, if the wound is quite large, then some stitches may be needed and the wound recovery will go through 4 overlapped stages, including
* The stage of hemostasis is the process of the wound being closed by clotting.
* The second stage is involved in the production of inflammatory cytokines in the prevention of infection.
* The third stage is proliferation in which the wound is rebuilt with new tissues made up of collagen and extracellular matrix.
and
* The masturbating stage in which collagens are converted, the recovery is completed, and the wound is fully closed.
Any interruption of the overlapped stage may induce the formation of scars similar to those of overproduction of inflammatory cytokines.
Unfortunately, if the immune system can not kill off all invaders over a short period of time normally between 3 to 8 weeks, it will compromise, leading to chronic inflammation in facilitating several chronic diseases such as cardiovascular disease and diabetes.
Betanin is phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to discover a potential ingredient for the treatment of diseases associated with inflammation, researchers investigated the effects of the natural pigment betanin on oxidative stress and inflammation in the kidneys of paraquat-treated rats.
Selected rats were injected with Paraquat intraperitoneally to induce renal damage, then randomly divided into four groups: a control group, a paraquat group, and two paraquat groups that were treated with betanin at 25 and 100 mg/kg/d three days before and two days after paraquat administration.
Betanin treated group showed a significant effect in alleviating the paraquat-incurred acute kidney injury, evidenced by histological improvement, reducing serum and urine markers for kidney injury compared to the untreated group.
The bioactive compound also attenuated the inflammation induced by the injection of Paraquat observed by the reduced expression of inflammatory proteins.
Furthermore, betanin also inhibits the kidney's oxidative stress through its antioxidant activity.
Based on the findings, researchers said, "betanin may have a protective effect against paraquat-induced acute kidney damage. The mechanisms of the protection appear to be the inhibition of oxidative stress and inflammation".
Taken altogether, betanin may be considered a supplement for the prevention and treatment of diseases associated with inflammation, pending the confirmation of a larger sample size and multicenter human study.
Intake of betanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betanin attenuates oxidative stress and inflammatory reaction in kidneys of paraquat-treated rats by Tan D1, Wang Y2, Bai B1, Yang X2, Han J. (PubMed)
(2) Mechanism of interaction of betanin and indicaxanthin with human myeloperoxidase and hypochlorous acid by Allegra M1, Furtmüller PG, Jantschko W, Zederbauer M, Tesoriere L, Livrea MA, Obinger C. (PubMed)
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