Kyle J. Norton
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
The condition is a widespread degenerative disease of skeletal joints and often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries and considered as a major health problem in both elderly men and women.
Scientists as of today do not know the exact causes of osteoporosis. However, they do know that certain factors are associated with the onset and progression of the disease.
Osteoporosis is a common disease among the elderly, probably due to the aging effect that induces nutrition deficiency such as
* Vitamin D insufficiency and reduced calcium absorption,
* Reduced hormone production, the drop of estrogen levels after menopause, can speed up bone loss.
* Reduced production of bone mass and increased bone reabsorption due to the balance shifts in favor of osteoclasts compared to those of osteoblasts.
Osteoclastogenesis is a procedure that includes many stages, that interfere with the specific stage of the process, diseases associated with imbalanced osteoclasts, and osteoblasts that may be preventable in the future.
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone and leads to bone resorption.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a potential compound for the improvement of bone mineral density, researchers examined the phytochemical Ligustilide (LIG), the main component of A. sinensis anti-osteoporotic effects.
According to the tested analysis, LIG significantly ameliorated the inhibition of bone formation in zebrafish caused by prednisolone.
Furthermore, the application also showed a strongly promoted osteoblast differentiation, including that of the pre-osteoblastic cell line MC3T3-E1 and bone marrow mesenchymal stem cells by reducing the oxidative stress to induce cell apoptosis by free radical H2O2 and enhancing the protein (Bcl-2) associated with anti-apoptotic functioning
The promotion of bone density of LIG was also found to induce the metabolic reaction of EGFR and ERK1/2 associated with instructions for making a receptor protein involved in bone formation by blocking the GPR30 signaling to induce bone mass increase.
Collectively, researchers said, "The results reveal that GPR30 is a positive switch for LIG to increase bone formation via regulation of EGFR, and these results provide evidence for the potential of LIG to treat osteoporosis".
Taken together, Herbal Angelica consists of LIG. maybe considered a functional herbal medicine for reducing the risk of osteoporosis, pending a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Ligustilide, a major bioactive component of Angelica sinensis, promotes bone formation via the GPR30/EGFR pathway by Yang F1,2, Lin ZW1,2, Huang TY1,2, Chen TT1,2, Cui J1,2, Li MY1,2, Hua YQ. (PubMed)
Wednesday, 30 August 2023
#Healthyfood #Honey Shows a Symptomatic Relief for Children's Nocturnal Cough and Sleep Difficulty, According to Studies
Kyle J. Norton
Scientists may have found a natural alternative for the treatment of chronic cough, according to studies. Cough is a natural human reflex that clears the throat of mucus or foreign irritants.
Although it is not common, coughing also is used to clear foreign substances and irritants infrequently associated with a certain lung infection.
Unlike an acute cough, chronic cough is a cough that lasts more than eight weeks. The most common causes of a chronic cough are a postnasal drip, asthma, and acid reflux.
Believe it or not, postnasal drip, asthma, and acid reflux are found in 90% of patients with a chronic cough.
According to the statistics, approximately, 2.% of US adults suffer from a chronic cough, and the risk of chronic cough of current smokers is substantially higher compared to non-smokers.
Besides smoking, people with chronic lung diseases such as asthma, bronchiectasis, COPD, and previous lung infections with scars are also at increased risk of developing a chronic cough.
Some researchers suggested that obese children may also be at risk of chronic conditions.
Dr. S Deane, the lead scientist in the assessment of the obese risk of chronic cough in children said, "Obese children have more respiratory symptoms than their normal-weight peers and respiratory-related pathology increases with increasing weight"
And, "Some will need specialist assessment (box 1). Obesity produces mechanical effects on respiratory system performance. Breathlessness, wheezing, and cough are not related to increased airway responsiveness and may respond more to weight loss than bronchodilator therapy. A significant number of obese children have signs and symptoms of obstructive sleep apnoea largely related to the effect of obesity on upper airway dimensions".
These results strongly suggested that the increased weight of obese children is the major risk factor for the development of chronic cough.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Scientists searching for a natural remedy for the treatment of a chronic cough without inducing adverse effects compared the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or Labiatae honey) to placebo (silan date extract) on nocturnal cough associated with childhood upper respiratory tract infections (URIs).
The study included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, Labiatae honey, or placebo administered 30 minutes before bedtime.
According to the results from 2 consecutive days, there was a significant improvement from the night before treatment to the night of treatment in the treatment group compared to the placebo.
Furthermore, according to the parents' review, the honey exhibited a higher than the silan date extract for symptomatic relief for their children's nocturnal cough and sleep difficulty.
In order to reveal more information about honey against a chronic cough in children, researchers examined the honey effect in the persistent post-infectious cough (PPC) that lasts more than three weeks or perhaps for many months.
The double-blind randomized controlled trial was conducted from 2008 to 2011 at the Baqiyatallah University Hospital, Tehran, Iran. included 97 adults who experienced PPC for more than three weeks randomly distributed into three groups.
Participants were given either a jam-like paste included honey plus coffee for the first group ('HC'), orprednisolone for the second group (steroid, 'S'), or guaifenesin for the third group (control, 'C').
All participants were told to dissolve a specified amount of their product in warm water and drink the solution every eight hours for one week.
The mean (+/- SD) cough scores pre- and post-treatment were: HC group 2.9 (0.3) pre-treatment and 0.2 (0.5) post-treatment (p < 0.001), and steroid ('S') group 3.0 (0.0) pre-treatment and 2.4 (0.6) post-treatment (p < 0.05)
The control ('C') group exerted mean (+/- SD) cough scores of 2.8 (0.4) pre-treatment and 2.7 (0.5) post-treatment (p > 0.05).
By Analysing the variance, researchers found that there is a significant difference between the mean cough frequency before and after treatment in the HC group, compared in the S group
Honey plus coffee was found to be the most effective modality for PPC, compared to other groups.
Taken together, honey may be considered an alternative remedy for the prevention and treatment of chronic coughs in children and adults, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study by Cohen HA1, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, Kozer E, Pomeranz A, Efrat H. (PubMed)
(2) Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial by Raeessi MA1, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi AA, Raeessi F. (PubMed)
(3) Obesity and the pulmonologist by S Deane and A Thomson. (PMC)
Scientists may have found a natural alternative for the treatment of chronic cough, according to studies. Cough is a natural human reflex that clears the throat of mucus or foreign irritants.
Although it is not common, coughing also is used to clear foreign substances and irritants infrequently associated with a certain lung infection.
Unlike an acute cough, chronic cough is a cough that lasts more than eight weeks. The most common causes of a chronic cough are a postnasal drip, asthma, and acid reflux.
Believe it or not, postnasal drip, asthma, and acid reflux are found in 90% of patients with a chronic cough.
According to the statistics, approximately, 2.% of US adults suffer from a chronic cough, and the risk of chronic cough of current smokers is substantially higher compared to non-smokers.
Besides smoking, people with chronic lung diseases such as asthma, bronchiectasis, COPD, and previous lung infections with scars are also at increased risk of developing a chronic cough.
Some researchers suggested that obese children may also be at risk of chronic conditions.
Dr. S Deane, the lead scientist in the assessment of the obese risk of chronic cough in children said, "Obese children have more respiratory symptoms than their normal-weight peers and respiratory-related pathology increases with increasing weight"
And, "Some will need specialist assessment (box 1). Obesity produces mechanical effects on respiratory system performance. Breathlessness, wheezing, and cough are not related to increased airway responsiveness and may respond more to weight loss than bronchodilator therapy. A significant number of obese children have signs and symptoms of obstructive sleep apnoea largely related to the effect of obesity on upper airway dimensions".
These results strongly suggested that the increased weight of obese children is the major risk factor for the development of chronic cough.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Scientists searching for a natural remedy for the treatment of a chronic cough without inducing adverse effects compared the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or Labiatae honey) to placebo (silan date extract) on nocturnal cough associated with childhood upper respiratory tract infections (URIs).
The study included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, Labiatae honey, or placebo administered 30 minutes before bedtime.
According to the results from 2 consecutive days, there was a significant improvement from the night before treatment to the night of treatment in the treatment group compared to the placebo.
Furthermore, according to the parents' review, the honey exhibited a higher than the silan date extract for symptomatic relief for their children's nocturnal cough and sleep difficulty.
In order to reveal more information about honey against a chronic cough in children, researchers examined the honey effect in the persistent post-infectious cough (PPC) that lasts more than three weeks or perhaps for many months.
The double-blind randomized controlled trial was conducted from 2008 to 2011 at the Baqiyatallah University Hospital, Tehran, Iran. included 97 adults who experienced PPC for more than three weeks randomly distributed into three groups.
Participants were given either a jam-like paste included honey plus coffee for the first group ('HC'), orprednisolone for the second group (steroid, 'S'), or guaifenesin for the third group (control, 'C').
All participants were told to dissolve a specified amount of their product in warm water and drink the solution every eight hours for one week.
The mean (+/- SD) cough scores pre- and post-treatment were: HC group 2.9 (0.3) pre-treatment and 0.2 (0.5) post-treatment (p < 0.001), and steroid ('S') group 3.0 (0.0) pre-treatment and 2.4 (0.6) post-treatment (p < 0.05)
The control ('C') group exerted mean (+/- SD) cough scores of 2.8 (0.4) pre-treatment and 2.7 (0.5) post-treatment (p > 0.05).
By Analysing the variance, researchers found that there is a significant difference between the mean cough frequency before and after treatment in the HC group, compared in the S group
Honey plus coffee was found to be the most effective modality for PPC, compared to other groups.
Taken together, honey may be considered an alternative remedy for the prevention and treatment of chronic coughs in children and adults, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study by Cohen HA1, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, Kozer E, Pomeranz A, Efrat H. (PubMed)
(2) Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial by Raeessi MA1, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi AA, Raeessi F. (PubMed)
(3) Obesity and the pulmonologist by S Deane and A Thomson. (PMC)
#Herbal #Angelica Extract Protects Bone Density Against the Risk of Osteoporosis, Researchers Show
Kyle J. Norton
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
The condition is a widespread degenerative disease of skeletal joints and is often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries, and is considered a major health problem in both elderly men and women.
Scientists as of today do not know the exact causes of osteoporosis. However, they do know that certain factors are associated with the onset and progression of the disease.
Osteoporosis is a common disease among the elderly, probably due to the aging effect that induces nutrition deficiency, vitamin D, reduced hormone production and production of bone mass, and increased bone reabsorption.
Osteoclastogenesis is a procedure processed in many stages. Interferes with the specific stage of the process, can induce the imbalanced osteoclasts and osteoblast.
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone and leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a potential compound for the protection of bone density, researchers examined the effect of Angelica Sinensis (AS) extract on RANKL-induced osteoclast differentiation.
The study is to examine the osteoclast precursor cell line bone marrow macrophages (BMMs) cultured and stimulated with RANKL followed by treatment with AS at several doses by regulating the complex networks involved in osteoclastogenesis and bone resorption.
According to the results of the experiment, AS extract protected bone density by inhibiting RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) in a dose-dependent manner without any evidence of cytotoxicity.
AS extract also inhibited the mRNA expression of transcription factors that are activated in immune cells and other cell types following stimulation by a variety of factors in RANKL-treated BMMs.
In other words, AS protected bone density integrity against osteoclastogenesis and inhibited bone resorption, the expression of cytokines, growth factors, and hormones induced by the treatment of RANKL.
Taken together, herbal Angelica may be considered an anti anti-steoclastogenesis and bone resorption remedy to protect the bone mineral density against the onset of osteoporosis, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells by Kong L, Zhao Q, Wang X, Zhu J, Hao D1, Yang C. (PubMed)
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
The condition is a widespread degenerative disease of skeletal joints and is often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries, and is considered a major health problem in both elderly men and women.
Scientists as of today do not know the exact causes of osteoporosis. However, they do know that certain factors are associated with the onset and progression of the disease.
Osteoporosis is a common disease among the elderly, probably due to the aging effect that induces nutrition deficiency, vitamin D, reduced hormone production and production of bone mass, and increased bone reabsorption.
Osteoclastogenesis is a procedure processed in many stages. Interferes with the specific stage of the process, can induce the imbalanced osteoclasts and osteoblast.
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone and leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a potential compound for the protection of bone density, researchers examined the effect of Angelica Sinensis (AS) extract on RANKL-induced osteoclast differentiation.
The study is to examine the osteoclast precursor cell line bone marrow macrophages (BMMs) cultured and stimulated with RANKL followed by treatment with AS at several doses by regulating the complex networks involved in osteoclastogenesis and bone resorption.
According to the results of the experiment, AS extract protected bone density by inhibiting RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) in a dose-dependent manner without any evidence of cytotoxicity.
AS extract also inhibited the mRNA expression of transcription factors that are activated in immune cells and other cell types following stimulation by a variety of factors in RANKL-treated BMMs.
In other words, AS protected bone density integrity against osteoclastogenesis and inhibited bone resorption, the expression of cytokines, growth factors, and hormones induced by the treatment of RANKL.
Taken together, herbal Angelica may be considered an anti anti-steoclastogenesis and bone resorption remedy to protect the bone mineral density against the onset of osteoporosis, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells by Kong L, Zhao Q, Wang X, Zhu J, Hao D1, Yang C. (PubMed)
#Healthyfood #Honey Shows a Statistically Significant Reduction of Pain, According to Studies
Kyle J. Norton
Scientists may have found a natural alternative pain relief remedy for alleviating pain, according to studies. found.
Pain relief is an action to remove pain, distress, and oppression by blocking the pain-transmitting information from nerve cells to the brain neurons.
Acute pain is any pain that lasts less than 6 months. Most cases of acute pain are due to physical damage such as soft tissue damage of a sprained ankle or a paper cut. Acute pain is relatively sharper and severe.
On the other hand, there are many risk factors associated with chronic pain. Some chronic pains can be caused by single factors such as diseases involving nerve damage to injuries that fail to heal properly. Others may result from several factors including diseases associated with normal aging.
Over-the-counter medications used for the treatment of pain include acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs).
Besides the gastrointestinal discomforts, long-term use of Tylenol may be additive. Overdoses or consumption together with alcohol, Tylenol can cause liver damage in severe cases.
If you are taking some over-the-counter medicine for pain-relieving, please make sure you know all the side effects of the preventive measure.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Researchers on finding a natural ingredient for pain relief examined the honey effect as adjunct pain therapy.
The pain relief of honey was the result of the contribution of the numerous phytochemicals and components, including the interaction of protein, amino acid, flavonoids, phenolics, organic acid, pigment, water, and (high) sugar content in honey.
These components work together to relieve pain by exerting antibacterial, antiinflammation, and immunomodulation properties.
According to additional differentiation, honey reduced pain through the expression of the level of the central and peripheral nervous system or at the autonomic receptor sites involved in pain transmission via the cyclooxygenase pathway in nociception and pain.
Furthermore, in the examined the honey pain relief in post-tonsillectomy treatment with or without adenoidectomy, researchers launched a randomized, double-blind, placebo-controlled study that included 140 patients, who were older than eight.
Patients were divided into two equal groups, honey, and placebo.
Compared the acetaminophen plus honey for the honey group, and acetaminophen plus placebo for the placebo group, researchers found that
* According to the visual analog scale (VAS) and the number of painkillers taken within the first three postoperative days, acetaminophen and acetaminophen plus honey groups showed a statistically significant reduction of pain.
*The reduced use of painkillers differed significantly in every five postoperative days.
* Pain awoke at night is also reduced with no difference between groups.
* Honey injection exerted negligible side effects
These results strongly showed that postoperative honey administration reduces postoperative pain and analgesic requirements in patients after tonsillectomy.
Taken together, there is no doubt that honey may be considered a functional remedy for pain relief with few side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norriton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Chapter 10 - Honey—A Natural Remedy for Pain Relief by Author links open overlay panelN.M.LazimA.Baharudin. (PubMed)
(2) Post Tonsillectomy Pain: Can Honey Reduce the Analgesic Requirements? by Peyman Boroumand,1 Mohammad Mahdi Zamani,2 Masoumeh Saeedi,1Omid Rouhbakhshfar,1 Seyed Reza Hosseini Motlagh,1 and Fatemeh Aarabi Moghaddam. (PubMed)
Scientists may have found a natural alternative pain relief remedy for alleviating pain, according to studies. found.
Pain relief is an action to remove pain, distress, and oppression by blocking the pain-transmitting information from nerve cells to the brain neurons.
Acute pain is any pain that lasts less than 6 months. Most cases of acute pain are due to physical damage such as soft tissue damage of a sprained ankle or a paper cut. Acute pain is relatively sharper and severe.
On the other hand, there are many risk factors associated with chronic pain. Some chronic pains can be caused by single factors such as diseases involving nerve damage to injuries that fail to heal properly. Others may result from several factors including diseases associated with normal aging.
Over-the-counter medications used for the treatment of pain include acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs).
Besides the gastrointestinal discomforts, long-term use of Tylenol may be additive. Overdoses or consumption together with alcohol, Tylenol can cause liver damage in severe cases.
If you are taking some over-the-counter medicine for pain-relieving, please make sure you know all the side effects of the preventive measure.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.
Researchers on finding a natural ingredient for pain relief examined the honey effect as adjunct pain therapy.
The pain relief of honey was the result of the contribution of the numerous phytochemicals and components, including the interaction of protein, amino acid, flavonoids, phenolics, organic acid, pigment, water, and (high) sugar content in honey.
These components work together to relieve pain by exerting antibacterial, antiinflammation, and immunomodulation properties.
According to additional differentiation, honey reduced pain through the expression of the level of the central and peripheral nervous system or at the autonomic receptor sites involved in pain transmission via the cyclooxygenase pathway in nociception and pain.
Furthermore, in the examined the honey pain relief in post-tonsillectomy treatment with or without adenoidectomy, researchers launched a randomized, double-blind, placebo-controlled study that included 140 patients, who were older than eight.
Patients were divided into two equal groups, honey, and placebo.
Compared the acetaminophen plus honey for the honey group, and acetaminophen plus placebo for the placebo group, researchers found that
* According to the visual analog scale (VAS) and the number of painkillers taken within the first three postoperative days, acetaminophen and acetaminophen plus honey groups showed a statistically significant reduction of pain.
*The reduced use of painkillers differed significantly in every five postoperative days.
* Pain awoke at night is also reduced with no difference between groups.
* Honey injection exerted negligible side effects
These results strongly showed that postoperative honey administration reduces postoperative pain and analgesic requirements in patients after tonsillectomy.
Taken together, there is no doubt that honey may be considered a functional remedy for pain relief with few side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norriton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Chapter 10 - Honey—A Natural Remedy for Pain Relief by Author links open overlay panelN.M.LazimA.Baharudin. (PubMed)
(2) Post Tonsillectomy Pain: Can Honey Reduce the Analgesic Requirements? by Peyman Boroumand,1 Mohammad Mahdi Zamani,2 Masoumeh Saeedi,1Omid Rouhbakhshfar,1 Seyed Reza Hosseini Motlagh,1 and Fatemeh Aarabi Moghaddam. (PubMed)
#Phytochemical 3,3'-Diindolylmethane In the Promotion of Enzymes and Antioxidant Activity Associated with Anti- Hematopoietic Injury, Researchers Find
Kyle J. Norton
Scientists may have found a bioactive ingredient for the protection of hematopoiesis with no side effects, according to studies.
Hematopoiesis is the process by which blood cells are formed, including the formation of all of the cellular components of blood and blood plasma.
1. Red blood cells with a function to transport oxygen and hemoglobin to the body.
2. White blood cells that form parts of the immune system, including
* T cells and B cells, that fight viruses, and tumors.
* Neutrophils that fight bacteria and fungi.
* Eosinophils that fight some parasites and initiate an inflammatory response.
* Basophils that release the histamines necessary for the inflammatory response.
* Macrophages, the first line of the immune response in the acute phase of infection.
3. Platelets (thrombocytes) for coagulation.
Diseases of the bone marrow, spleen, lymph nodes, and thymus may affect the process of hematopoiesis, leading to various diseases of the hematopoietic system.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
On finding a natural compound for the treatment of hematopoietic injury, researchers examined the 3,3'-Diindolylmethane (DIM) effect on the hematopoietic system injury induced by total body irradiation (TBI) that leads to the generation of intracellular reactive oxygen species (ROS) and DNA damage.
In TBI-induced lethality mice, DIM ameliorated TBI-induced hematopoietic injury by inhibiting the production of ROS production in hematopoietic stem cells (HSCs).
Furthermore, DIM improved the bone marrow (BM) HSC frequency, hematopoietic progenitor cell (HPC) clonogenic function, and multilineage engraftment after transplantation in tested mice.
In an additional analysis of DIM anti-hematopoietic injury, researchers found that DIM promotes the genes associated with the increased production of antioxidant enzymes (nuclear factor erythroid 2-related factor 2 (Nrf2)) in the hematopoietic stem cells (HSCs) and decreased the production of free radicals (NADPH oxidase 4 (NOX4)).
DIM also protected the cells against apoptosis by increasing the expression of the anti-apoptotic protein (Bcl-2) and decreasing the expression of the pro-apoptotic protein (Bax).
The results strongly suggested that DIM attenuates TBI-induced hematopoietic injury through the inhibition of both oxidative stress in HSCs and hematopoietic cell apoptosis.
Dr. Lu L and colleagues wrote in the final report, "DIM protected BM hematopoietic cells against ionizing radiation and led to increased clonogenicity in vitro. Therefore, DIM has the potential to be used as an effective radioprotectant to ameliorate TBI-induced hematopoietic injury".
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the protection and treatment of hematopoietic injury, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice by Lu L1, Dong J2, Li D2, Zhang J2, Fan S. (PubMed)
Scientists may have found a bioactive ingredient for the protection of hematopoiesis with no side effects, according to studies.
Hematopoiesis is the process by which blood cells are formed, including the formation of all of the cellular components of blood and blood plasma.
1. Red blood cells with a function to transport oxygen and hemoglobin to the body.
2. White blood cells that form parts of the immune system, including
* T cells and B cells, that fight viruses, and tumors.
* Neutrophils that fight bacteria and fungi.
* Eosinophils that fight some parasites and initiate an inflammatory response.
* Basophils that release the histamines necessary for the inflammatory response.
* Macrophages, the first line of the immune response in the acute phase of infection.
3. Platelets (thrombocytes) for coagulation.
Diseases of the bone marrow, spleen, lymph nodes, and thymus may affect the process of hematopoiesis, leading to various diseases of the hematopoietic system.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
On finding a natural compound for the treatment of hematopoietic injury, researchers examined the 3,3'-Diindolylmethane (DIM) effect on the hematopoietic system injury induced by total body irradiation (TBI) that leads to the generation of intracellular reactive oxygen species (ROS) and DNA damage.
In TBI-induced lethality mice, DIM ameliorated TBI-induced hematopoietic injury by inhibiting the production of ROS production in hematopoietic stem cells (HSCs).
Furthermore, DIM improved the bone marrow (BM) HSC frequency, hematopoietic progenitor cell (HPC) clonogenic function, and multilineage engraftment after transplantation in tested mice.
In an additional analysis of DIM anti-hematopoietic injury, researchers found that DIM promotes the genes associated with the increased production of antioxidant enzymes (nuclear factor erythroid 2-related factor 2 (Nrf2)) in the hematopoietic stem cells (HSCs) and decreased the production of free radicals (NADPH oxidase 4 (NOX4)).
DIM also protected the cells against apoptosis by increasing the expression of the anti-apoptotic protein (Bcl-2) and decreasing the expression of the pro-apoptotic protein (Bax).
The results strongly suggested that DIM attenuates TBI-induced hematopoietic injury through the inhibition of both oxidative stress in HSCs and hematopoietic cell apoptosis.
Dr. Lu L and colleagues wrote in the final report, "DIM protected BM hematopoietic cells against ionizing radiation and led to increased clonogenicity in vitro. Therefore, DIM has the potential to be used as an effective radioprotectant to ameliorate TBI-induced hematopoietic injury".
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the protection and treatment of hematopoietic injury, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice by Lu L1, Dong J2, Li D2, Zhang J2, Fan S. (PubMed)
Encapsulation of Asafoetida (ASF) and a CUR Found in #Herbal #Turmeric Provide Protection of the Onset of #Colitis, Scientists Say
Kyle J. Norton
Colitis is a condition associated with inflammation of the inner lining of the colon.
There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.
The most common symptoms of colitis are totally depending on the type, including abdominal pain, cramping, diarrhea, with or without blood in the stool.
Types of colitis according to the Catholic University of the Sacred Heart, include
microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis.
Epidemiologically, people with untreated colitis may experience complications of
* Congenital abnormalities
Women who are pregnant with Ulcerative colitis are associated with a significantly increased risk of some selected congenital abnormalities (limb deficiencies, obstructive urinary, and multiple congenital abnormalities) according to the birth outcomes in women with ulcerative colitis examined in nationwide.
* Nutritional deficiency
Malnutrition, particularly protein-energy malnutrition and vitamin and micronutrient deficiencies, as well as dysregulation of the intestinal microbiota, are common features of IBD.
Conventionally, besides treating colitis with antibiotics, certain medications also are prescribed to improve the symptoms and quality of life of the patients, including anti-diarrheal medications.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a natural compound for the treatment of colitis, researchers examined the effects of a novel gut health product (GHP), an encapsulation of asafoetida (ASF) and a CUR complex used as a carrier agent to encapsulate bioactive components for the treatment of colitis.
According to the rat model of 5%, dextran sulfate sodium (DSS) induced UC, treatment of GHP significantly attenuated the disease activity index, colitis score, histopathological changes, and myeloperoxidase activity.
Furthermore, GHP also demonstrated significant protective effects against DSS-induced colitis.
Additionally, in an animal model of dextran sodium sulfate (DSS)-induced colitis, a specific, curcumin preparation containing essential turmeric oils (ETO-curcumin) compared to standard curcumin at three specific doses (0, 5, 25, or 50 mg/kg), both ETO and standard curcumin treatments provided protection against DSS-induced inflammation.
However, according to the tested assays, ETO-curcumin improved disease activity index (DAI) dose-dependently, compared to the anti-inflammatory efficacy of standard curcumin remained constant.
In other words, ETO-curcumin was superior in the expression of anti-inflammatory efficacy compared to standard curcumin.
Moreover, ETO-curcumin displayed anti-colitis activity in the colon by exerting anti-inflammatory cytokines including IL-10 and IL-11 as well as FOXP3.
Collectively, Dr. Toden S., the lead scientist, wrote in the final report, " The combined treatment of curcumin and essential turmeric oils provides superior protection from DSS-induced colitis than curcumin alone, highlighting the anti-inflammatory potential of turmeric".
Taken altogether, turmeric plus essential turmeric oils may be considered supplements for the prevention of colitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Preparation, characterization, and anti-colitis activity of curcumin-asafoetida complex encapsulated in turmeric nanofiber by Gopi S1, Amalraj A2, Jude S2, Varma K2, Sreeraj TR2, Haponiuk JT3, Thomas S. (PubMed)
(2) Essential turmeric oils enhance the anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis by Toden S1, Theiss AL2, Wang X3, Goel A. (PubMed)
(3) Colitis - The Complications by Kyle J. Norton
Colitis is a condition associated with inflammation of the inner lining of the colon.
There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.
The most common symptoms of colitis are totally depending on the type, including abdominal pain, cramping, diarrhea, with or without blood in the stool.
Types of colitis according to the Catholic University of the Sacred Heart, include
microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis.
Epidemiologically, people with untreated colitis may experience complications of
* Congenital abnormalities
Women who are pregnant with Ulcerative colitis are associated with a significantly increased risk of some selected congenital abnormalities (limb deficiencies, obstructive urinary, and multiple congenital abnormalities) according to the birth outcomes in women with ulcerative colitis examined in nationwide.
* Nutritional deficiency
Malnutrition, particularly protein-energy malnutrition and vitamin and micronutrient deficiencies, as well as dysregulation of the intestinal microbiota, are common features of IBD.
Conventionally, besides treating colitis with antibiotics, certain medications also are prescribed to improve the symptoms and quality of life of the patients, including anti-diarrheal medications.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a natural compound for the treatment of colitis, researchers examined the effects of a novel gut health product (GHP), an encapsulation of asafoetida (ASF) and a CUR complex used as a carrier agent to encapsulate bioactive components for the treatment of colitis.
According to the rat model of 5%, dextran sulfate sodium (DSS) induced UC, treatment of GHP significantly attenuated the disease activity index, colitis score, histopathological changes, and myeloperoxidase activity.
Furthermore, GHP also demonstrated significant protective effects against DSS-induced colitis.
Additionally, in an animal model of dextran sodium sulfate (DSS)-induced colitis, a specific, curcumin preparation containing essential turmeric oils (ETO-curcumin) compared to standard curcumin at three specific doses (0, 5, 25, or 50 mg/kg), both ETO and standard curcumin treatments provided protection against DSS-induced inflammation.
However, according to the tested assays, ETO-curcumin improved disease activity index (DAI) dose-dependently, compared to the anti-inflammatory efficacy of standard curcumin remained constant.
In other words, ETO-curcumin was superior in the expression of anti-inflammatory efficacy compared to standard curcumin.
Moreover, ETO-curcumin displayed anti-colitis activity in the colon by exerting anti-inflammatory cytokines including IL-10 and IL-11 as well as FOXP3.
Collectively, Dr. Toden S., the lead scientist, wrote in the final report, " The combined treatment of curcumin and essential turmeric oils provides superior protection from DSS-induced colitis than curcumin alone, highlighting the anti-inflammatory potential of turmeric".
Taken altogether, turmeric plus essential turmeric oils may be considered supplements for the prevention of colitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Preparation, characterization, and anti-colitis activity of curcumin-asafoetida complex encapsulated in turmeric nanofiber by Gopi S1, Amalraj A2, Jude S2, Varma K2, Sreeraj TR2, Haponiuk JT3, Thomas S. (PubMed)
(2) Essential turmeric oils enhance the anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis by Toden S1, Theiss AL2, Wang X3, Goel A. (PubMed)
(3) Colitis - The Complications by Kyle J. Norton
#Organosulfides, the Bioactive compoundsisolated from Garlic Process Strong Anti #SkinCancer Activity, Researchers Suggest
Kyle J. Norton
Polysulfides isolated from the organosulfides may have a profound effect in reducing the risk and treatment of skin cancer, according to studies.
Skin, a large organ that forms the out layers of our body has a serval layer of ectodermal tissue and protects the underlying muscles, bones, ligaments and internal organs against foreign pathogenic invasion.
Skin cancer is a medical condition characterized by disordered and irregular cell growth in the skin.
Most cases of primary skin cancer start in the cell on the surface of the inner lining of the skin. At the advanced stage, the cancerous cells can travel a distance away from the skin to infect other healthy tissues and organs through blood and fluid circulation.
There are 3 main types of cells in the top layer of the skin (called the epidermis):
Squamous cells, Basal cells, and Melanocytes.
Long-term cumulative sun exposure is one of the major causes of basal cell and squamous cell skin cancer. Exposure to ultraviolet (UV) radiation is the leading cause of melanoma.
Certain risk factors that make some people more susceptible to the development of skin cancer than others include the increase in age, weakened immune system, gender, skin tone, genetic preposition, and family history.
Some researchers also suggested that the general knowledge about the protection of skin against the onset of skin cancer is lacking, therefore, more education in this field may be necessary before the prevalence of skin cancer can be reduced.
Dr. Lee Wheless, the lead scientist in the concern of the association between skin characteristics and skin cancer prevention behaviors said, "Behaviors such as sunscreen use and wearing sun-protective clothing are thought to prevent certain types of skin cancer and precancerous lesions".
However, "The overall prevalence of prevention behaviors was low. Those with phenotypic risk factors for skin cancer were most likely to use sunscreen and sun-protective clothing. Those with high-risk skin cancer phenotypes may also be those who are most receptive to skin cancer prevention educational interventions".
Polysulfides are phytochemicals in a class of chemical compounds containing chains of sulfur atoms, belonging to the group of Organosulfides found abundantly in the oxidized product, including beer, wine, whiskey, garlic oil, etc.
In the concern of incidence of skin cancer which increases at an alarming rate, researchers at the National Taiwan University evaluated the anti-skin cancer activity of sulfur metabolites in garlic oil.
Diallyl trisulfide (DATS), a member of polysulfides was found to be more potent than mono- and disulfides against skin cancer.
Injection of DATS inhibited cell growth of human melanoma A375 and basal cell carcinoma (BCC) cells by increasing the cytotoxicity of the reactive oxygen species (ROS).
Furthermore, DATS also induced apoptosis of skin cancer cells through inducing the DNA damage and through cell cycle arrest at the G2/M phase, endoplasmic reticulum (ER) stress associated with the cancer cell proliferation and survival, and mitochondria-mediated apoptosis.
These results indicated the importance of DATS in the prevention and treatment of skin cancer by focusing on molecular mechanisms.
Furthermore, in the in-depth analysis of the effects of Diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS), extracts from crushed garlic by steam-distillation against human melanoma A375 cells and basal cell carcinoma cells, researchers showed that DATS reveals better growth inhibition of A375 and BCC cells than DADS and DAS do.
Similar to the previous study, DATS increased intracellular reactive oxygen species (ROS) generation in the induction of cytotoxicity to the tested cancer cell lines.
The cell viability analysis reconfirmed the previous finding that DATS kills tested cancer cells in G(2)/M arrest.
Interestingly, DATS activated the p53 pathway in response to the oxidative DNA damage.
Where p53 is a protein associated with the regulation of the cell cycle and functions as a tumor suppression.
Dr. Wang HC, the lead scientist wrote in the final report of the experiment, "DATS also displayed a selective target of growth inhibition between skin cancer cells and normal keratinocyte HaCaT cells".
Taken altogether, Diallyl trisulfide (DATS) a bioactive compound from garlic may be used for the prevention and treatment of skin cancer, pending to reconfirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression by Wang HC1, Pao J, Lin SY, Sheen LY. (PubMed)
(2) Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis By Wang HC1, Yang JH, Hsieh SC, Sheen LY. (PubMed)
(3) Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis by Cherng JM1, Tsai KD, Perng DS, Wang JS, Wei CC, Lin JC. (PubMed)
(4) The association between skin characteristics and skin cancer prevention behaviors by Lee Wheless,1 Ingo Ruczinski,3 Rhoda M. Alani,6,7 Sandra Clipp,4,10Judith Hoffman-Bolton,4,10 Timothy J. Jorgensen,4,11 Nanette J. Liégeois,6,8,9Paul T. Strickland,5 and Anthony J. Alberg. (PMC)
Polysulfides isolated from the organosulfides may have a profound effect in reducing the risk and treatment of skin cancer, according to studies.
Skin, a large organ that forms the out layers of our body has a serval layer of ectodermal tissue and protects the underlying muscles, bones, ligaments and internal organs against foreign pathogenic invasion.
Skin cancer is a medical condition characterized by disordered and irregular cell growth in the skin.
Most cases of primary skin cancer start in the cell on the surface of the inner lining of the skin. At the advanced stage, the cancerous cells can travel a distance away from the skin to infect other healthy tissues and organs through blood and fluid circulation.
There are 3 main types of cells in the top layer of the skin (called the epidermis):
Squamous cells, Basal cells, and Melanocytes.
Long-term cumulative sun exposure is one of the major causes of basal cell and squamous cell skin cancer. Exposure to ultraviolet (UV) radiation is the leading cause of melanoma.
Certain risk factors that make some people more susceptible to the development of skin cancer than others include the increase in age, weakened immune system, gender, skin tone, genetic preposition, and family history.
Some researchers also suggested that the general knowledge about the protection of skin against the onset of skin cancer is lacking, therefore, more education in this field may be necessary before the prevalence of skin cancer can be reduced.
Dr. Lee Wheless, the lead scientist in the concern of the association between skin characteristics and skin cancer prevention behaviors said, "Behaviors such as sunscreen use and wearing sun-protective clothing are thought to prevent certain types of skin cancer and precancerous lesions".
However, "The overall prevalence of prevention behaviors was low. Those with phenotypic risk factors for skin cancer were most likely to use sunscreen and sun-protective clothing. Those with high-risk skin cancer phenotypes may also be those who are most receptive to skin cancer prevention educational interventions".
Polysulfides are phytochemicals in a class of chemical compounds containing chains of sulfur atoms, belonging to the group of Organosulfides found abundantly in the oxidized product, including beer, wine, whiskey, garlic oil, etc.
In the concern of incidence of skin cancer which increases at an alarming rate, researchers at the National Taiwan University evaluated the anti-skin cancer activity of sulfur metabolites in garlic oil.
Diallyl trisulfide (DATS), a member of polysulfides was found to be more potent than mono- and disulfides against skin cancer.
Injection of DATS inhibited cell growth of human melanoma A375 and basal cell carcinoma (BCC) cells by increasing the cytotoxicity of the reactive oxygen species (ROS).
Furthermore, DATS also induced apoptosis of skin cancer cells through inducing the DNA damage and through cell cycle arrest at the G2/M phase, endoplasmic reticulum (ER) stress associated with the cancer cell proliferation and survival, and mitochondria-mediated apoptosis.
These results indicated the importance of DATS in the prevention and treatment of skin cancer by focusing on molecular mechanisms.
Furthermore, in the in-depth analysis of the effects of Diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS), extracts from crushed garlic by steam-distillation against human melanoma A375 cells and basal cell carcinoma cells, researchers showed that DATS reveals better growth inhibition of A375 and BCC cells than DADS and DAS do.
Similar to the previous study, DATS increased intracellular reactive oxygen species (ROS) generation in the induction of cytotoxicity to the tested cancer cell lines.
The cell viability analysis reconfirmed the previous finding that DATS kills tested cancer cells in G(2)/M arrest.
Interestingly, DATS activated the p53 pathway in response to the oxidative DNA damage.
Where p53 is a protein associated with the regulation of the cell cycle and functions as a tumor suppression.
Dr. Wang HC, the lead scientist wrote in the final report of the experiment, "DATS also displayed a selective target of growth inhibition between skin cancer cells and normal keratinocyte HaCaT cells".
Taken altogether, Diallyl trisulfide (DATS) a bioactive compound from garlic may be used for the prevention and treatment of skin cancer, pending to reconfirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression by Wang HC1, Pao J, Lin SY, Sheen LY. (PubMed)
(2) Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis By Wang HC1, Yang JH, Hsieh SC, Sheen LY. (PubMed)
(3) Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis by Cherng JM1, Tsai KD, Perng DS, Wang JS, Wei CC, Lin JC. (PubMed)
(4) The association between skin characteristics and skin cancer prevention behaviors by Lee Wheless,1 Ingo Ruczinski,3 Rhoda M. Alani,6,7 Sandra Clipp,4,10Judith Hoffman-Bolton,4,10 Timothy J. Jorgensen,4,11 Nanette J. Liégeois,6,8,9Paul T. Strickland,5 and Anthony J. Alberg. (PMC)
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