Kyle J. Norton
Scientists may have found a natural alternative for the treatment of reflux esophagitis, some studies found.
Acid Reflux or heartburn is a condition characterized by the going back up of acidic stomach contents to the esophagus. Most cases of acid reflux are happened immediately after eating causing a burning sensation or pain in the lower chest area.
According to the statistics, in the US, approximately, 20% of people with acid reflux will develop gastroesophageal reflux disease (GERD). More than 65% of people who suffer from acid reflux are 40 years old or older. And, 15 to 30 5 of the U.S. population has GERD.
Too much tea, coffee, and alcohol smoking pregnancy, obesity, and eating habits such as eating close to bedtime, eating a large meal, and eating fatty and fried foods are some of the risk factors that initiate the early onset of acid reflux, according to epidemiological studies.
Believe it or not, long-term intake of certain medications such as bronchodilators for asthma, progestin for birth control or to treat abnormal menstrual bleeding, sedatives for insomnia and anxiety, calcium channel blockers for high blood pressure.
Dr. Zeynel Mungan and colleagues in examing the medication risk of GERD wrote, "Gastroesophageal reflux disease (GERD), which is common in many communities, is associated with structural factors, eating habits, and the use of certain drugs".
And, "The use of such drugs can lead to the emergence of GERD and can also exacerbate existing reflux symptoms. These drugs can contribute to GERD by directly causing mucosal damage, by reducing lower esophageal sphincter pressure (LESP), or by affecting esophagogastric motility".
Therefore, if you currently taking some of the aforementioned medication, please make sure that you know all the side effects for preventive measure.
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Scientists finding a natural remedy for the treatment of acid reflux investigated the honey effect on reflux oesophagitis (RE).
Injection honey displayed a strong effect on reflux oesophagitis by inhibiting the free radical expression which has been found to be the mediator in the generation of RE.
Furthermore, besides inhibiting the overexpression of free radicals, honey also promotes the production of antioxidant enzymes in the host, leading to a balanced ratio of free radicals and antioxidants in the body.
Moreover, honey injection also reduced the levels of inflammation by inhibiting the nitric oxide and prostaglandin E2 production associated with free radicals and inflammation, respectively.
The effects of honey against RE are also attributed to the nature of high density, high viscosity, and low surface tension, which makes them stay longer in the esophagus as a coating on the mucous membrane.
Additionally, researchers also found that the anti-RE activity of honey was also due to its nonperoxide antibacterial activity.
The findings suggested honey inhibits the onset of progression RE through a number of mechanisms, including proteins associated with the production of pro-inflammatory cytokines and antioxidant enzymes produced by the honey and the host.
Taken altogether, honey may be considered a functional remedy for the prevention and combined with the primary therapy for the treatment of reflux esophagitis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Honey - A nutrient with medicinal property in reflux oesophagitis by Mahantayya V. Math,* Rita M. Khadkikar, and Yashoda R. Kattimani. (PubMed)
(2) Which drugs are risk factors for the development of gastroesophageal reflux disease? by Zeynel Mungan, Binnur Pınarbaşı Şimşek. (University School of Medicine and İstinye University School of Medicine)
Saturday, 26 August 2023
#Broccoli' #Sulforaphane (SFN) Exerts Chemo-Preventive Activity by Controlling CancerCell #Carcinogenesis, Studies Find
Kyle J. Norton
Cancer is the class of diseases associated with the growth of cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American Cancer Society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Chemo-drugs are a class of conventional medicine used for the treatment of cancers. including 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate.
Compared to other treatments, chemotherapy targets cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
Chemo drugs have been found to improve the survival rate of cancer patients. However, they also induce significant side effects.
The most common side effects of chemo-drugs are fatigue, hair loss, easy bruising, and bleeding. infection, anemia (low red blood cell counts) nausea and vomiting, appetite changes, and constipation.
The side effects of chemo drugs are the results of damage to the healthy blood-forming cells in the bone marrow, hair follicles, and cells in the mouth, digestive tract, and reproductive system.
According to the American Cancer Society, some chemo drugs have also been found to damage cells in the heart, kidneys, bladder, lungs, and nervous system.
Chemoprevention is the use of a medication, vitamin, or supplement to prevent the initiation of cancer.
In finding a potential plant for the treatment of cancers, researchers compared the effects of
The Brassica family of cruciferous vegetables such as broccoli is a rich source of isothiocyanates and sulforaphane (SFN) as a chemopreventive phytochemical.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
According to the differentiation, sulforaphane (SFN) exerted its potent chemopreventive agent based on its ability to target multiple mechanisms within the cell to control carcinogenesis.
More precisely, anti-inflammatory, pro-apoptotic, and modulation of histones are some of the more important and known mechanisms by which SFN demonstrates chemoprevention.
Furthermore, The effect of SFN on cancer stem cells is another area of interest that has been explored in recent years and may contribute to its chemopreventive properties.
Based on the results, researchers said, "In this paper, we briefly review structure, pharmacology, and preclinical studies highlighting chemopreventive effects of SFN".
Taken together, broccoli consisting of SFN may be considered a chemopreventive functional food, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review by Bayat Mokhtari R1,2,3,4, Baluch N5, Homayouni TS6, Morgatskaya E6, Kumar S6, Kazemi P6, Yeger H. (PubMed)https://www.ncbi.nlm.nih.gov/pubmed/28735362
Cancer is the class of diseases associated with the growth of cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American Cancer Society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Chemo-drugs are a class of conventional medicine used for the treatment of cancers. including 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate.
Compared to other treatments, chemotherapy targets cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
Chemo drugs have been found to improve the survival rate of cancer patients. However, they also induce significant side effects.
The most common side effects of chemo-drugs are fatigue, hair loss, easy bruising, and bleeding. infection, anemia (low red blood cell counts) nausea and vomiting, appetite changes, and constipation.
The side effects of chemo drugs are the results of damage to the healthy blood-forming cells in the bone marrow, hair follicles, and cells in the mouth, digestive tract, and reproductive system.
According to the American Cancer Society, some chemo drugs have also been found to damage cells in the heart, kidneys, bladder, lungs, and nervous system.
Chemoprevention is the use of a medication, vitamin, or supplement to prevent the initiation of cancer.
In finding a potential plant for the treatment of cancers, researchers compared the effects of
The Brassica family of cruciferous vegetables such as broccoli is a rich source of isothiocyanates and sulforaphane (SFN) as a chemopreventive phytochemical.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
According to the differentiation, sulforaphane (SFN) exerted its potent chemopreventive agent based on its ability to target multiple mechanisms within the cell to control carcinogenesis.
More precisely, anti-inflammatory, pro-apoptotic, and modulation of histones are some of the more important and known mechanisms by which SFN demonstrates chemoprevention.
Furthermore, The effect of SFN on cancer stem cells is another area of interest that has been explored in recent years and may contribute to its chemopreventive properties.
Based on the results, researchers said, "In this paper, we briefly review structure, pharmacology, and preclinical studies highlighting chemopreventive effects of SFN".
Taken together, broccoli consisting of SFN may be considered a chemopreventive functional food, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review by Bayat Mokhtari R1,2,3,4, Baluch N5, Homayouni TS6, Morgatskaya E6, Kumar S6, Kazemi P6, Yeger H. (PubMed)https://www.ncbi.nlm.nih.gov/pubmed/28735362
#Healthy Food #Honey Improves the Antioxidant Status in Reducing the Risk of Cholesterol Overexpression, Researchers Say
Kyle J. Norton
Scientists may have found a natural alternative for the treatment of hyperlipidemia according to a study. Hyperlipidemia is a condition of high levels of cholesterol in the bloodstream. Cholesterol is a waxy substance that is needed for the body to build cell walls, aid digestion, and make steroid hormones and vitamin D.
Cholesterol can be produced by the liver or by eating some fatty foods. There are 2 types of cholesterol, the low-density lipoprotein (LDL) which carries the aforementioned functions, and the high-density lipoprotein (HDL) which returns the cholesterol to the liver for reuse.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lower than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
Although there are many risk factors associated with the onset of hyperlipidemia, some researchers suggested that the association between widespread obesity and hyperlipidemia in US adults is worrisome in the scientific community.
Dr. Boudewijn Klop and their colleagues at the Diabetes and Vascular Centre, Sint Franciscus Gasthuis wrote, "Obesity increases cardiovascular risk through risk factors such as increased fasting plasma triglycerides, high LDL cholesterol, low HDL cholesterol, elevated blood glucose, and insulin levels and high blood pressure. Novel lipid-dependent, metabolic risk factors associated with obesity are the presence of the small dense LDL phenotype, postprandial hyperlipidemia with an accumulation of atherogenic remnants, and hepatic overproduction of apoB-containing lipoproteins".
And, "All these lipid abnormalities are typical features of the metabolic syndrome and may be associated with a pro-inflammatory gradient which in part may originate in the adipose tissue itself and directly affect the endothelium".
The results strongly suggested the association between obesity and the onset of abnormal blood cholesterol in the contributes to many complications and diseases.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
Scientists on finding a natural compound for the treatment of cholesterol examined honey's effects on patients with high cholesterol concentrations.
The study included 60 volunteers with high cholesterol, stratified according to gender and hydroxymethyl-glutaryl-coenzyme A reductase inhibitor (statin) treatment (yes/no), randomized to receive 75 g of the honey solution or a honey-comparable sugar solution once daily over a period of 14 days.
Measurements repeated 2 weeks later, showed that BMI and high-density lipoprotein (HDL) cholesterol values were significantly correlated (r = -0.487; P < .001) as were BMI and a lower ratio of low-density lipoprotein (LDL) cholesterol to HDL cholesterol (r = 0.420; P < .001).
In other words, with the injection of honey, subjects with a high BMI had a lower HDL cholesterol value.
Even though neither solution influenced significantly cholesterol or triglyceride values in the total group; substituting honey for sugar in their diet was shown to reduce the BMI and lower the LDL cholesterol value.
The finding suggested honey does not have a direct effect on normalizing the levels of blood cholesterol but indirectly reduces the patient's BMI value, which has been found to have strong effects in decreasing the levels of cholesterol.
Furthermore, according to research presented at the national meeting of the American Chemical Society, the world's largest scientific society, honey fights cholesterol as well as some fruits and vegetables.
The study included 25 men between the ages of 18 - and 68 who were given a mixture of water and honey, about four tablespoons per 16-ounce glass in a five-week.
A blood sample withdrawn at the end of the experience showed reduced levels of cholesterol by improving the antioxidant levels in the blood.
Moreover, the application of the mixture also has a significant effect in reducing the risk of atherosclerosis caused by plaque such as cholesterol and other substances build up on the arterial wall.
The onset of atherosclerosis is a major cause of heart disease in the US.
The results suggested that replacing the use of sweetening agents, like sugar with honey may improve the antioxidant status in reducing the risk of cholesterol overexpression in the bloodstream.
Taken together, honey may be considered a functional remedy for the prevention and treatment of high blood cholesterol, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on serum cholesterol and lipid values by Münstedt K1, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. (PubMed)
(2) Honey Fights Cholesterol As Well As Some Fruits And Vegetables by American Chemical Society. (Science Daily)
(3) Dyslipidemia in Obesity: Mechanisms and Potential Targets by Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas. (PMC)
Scientists may have found a natural alternative for the treatment of hyperlipidemia according to a study. Hyperlipidemia is a condition of high levels of cholesterol in the bloodstream. Cholesterol is a waxy substance that is needed for the body to build cell walls, aid digestion, and make steroid hormones and vitamin D.
Cholesterol can be produced by the liver or by eating some fatty foods. There are 2 types of cholesterol, the low-density lipoprotein (LDL) which carries the aforementioned functions, and the high-density lipoprotein (HDL) which returns the cholesterol to the liver for reuse.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lower than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
Although there are many risk factors associated with the onset of hyperlipidemia, some researchers suggested that the association between widespread obesity and hyperlipidemia in US adults is worrisome in the scientific community.
Dr. Boudewijn Klop and their colleagues at the Diabetes and Vascular Centre, Sint Franciscus Gasthuis wrote, "Obesity increases cardiovascular risk through risk factors such as increased fasting plasma triglycerides, high LDL cholesterol, low HDL cholesterol, elevated blood glucose, and insulin levels and high blood pressure. Novel lipid-dependent, metabolic risk factors associated with obesity are the presence of the small dense LDL phenotype, postprandial hyperlipidemia with an accumulation of atherogenic remnants, and hepatic overproduction of apoB-containing lipoproteins".
And, "All these lipid abnormalities are typical features of the metabolic syndrome and may be associated with a pro-inflammatory gradient which in part may originate in the adipose tissue itself and directly affect the endothelium".
The results strongly suggested the association between obesity and the onset of abnormal blood cholesterol in the contributes to many complications and diseases.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
Scientists on finding a natural compound for the treatment of cholesterol examined honey's effects on patients with high cholesterol concentrations.
The study included 60 volunteers with high cholesterol, stratified according to gender and hydroxymethyl-glutaryl-coenzyme A reductase inhibitor (statin) treatment (yes/no), randomized to receive 75 g of the honey solution or a honey-comparable sugar solution once daily over a period of 14 days.
Measurements repeated 2 weeks later, showed that BMI and high-density lipoprotein (HDL) cholesterol values were significantly correlated (r = -0.487; P < .001) as were BMI and a lower ratio of low-density lipoprotein (LDL) cholesterol to HDL cholesterol (r = 0.420; P < .001).
In other words, with the injection of honey, subjects with a high BMI had a lower HDL cholesterol value.
Even though neither solution influenced significantly cholesterol or triglyceride values in the total group; substituting honey for sugar in their diet was shown to reduce the BMI and lower the LDL cholesterol value.
The finding suggested honey does not have a direct effect on normalizing the levels of blood cholesterol but indirectly reduces the patient's BMI value, which has been found to have strong effects in decreasing the levels of cholesterol.
Furthermore, according to research presented at the national meeting of the American Chemical Society, the world's largest scientific society, honey fights cholesterol as well as some fruits and vegetables.
The study included 25 men between the ages of 18 - and 68 who were given a mixture of water and honey, about four tablespoons per 16-ounce glass in a five-week.
A blood sample withdrawn at the end of the experience showed reduced levels of cholesterol by improving the antioxidant levels in the blood.
Moreover, the application of the mixture also has a significant effect in reducing the risk of atherosclerosis caused by plaque such as cholesterol and other substances build up on the arterial wall.
The onset of atherosclerosis is a major cause of heart disease in the US.
The results suggested that replacing the use of sweetening agents, like sugar with honey may improve the antioxidant status in reducing the risk of cholesterol overexpression in the bloodstream.
Taken together, honey may be considered a functional remedy for the prevention and treatment of high blood cholesterol, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on serum cholesterol and lipid values by Münstedt K1, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. (PubMed)
(2) Honey Fights Cholesterol As Well As Some Fruits And Vegetables by American Chemical Society. (Science Daily)
(3) Dyslipidemia in Obesity: Mechanisms and Potential Targets by Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas. (PMC)
#Propionic Acid (HDMPPAK) Found in #KoreanCabbage Inhibits the Risk of #Atherosclerosis, Researchers Show
Kyle J. Norton
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to supply oxygen and nutrients and remove of metabolic wastes.
Heart disease is a group of medical conditions caused by narrowed or blocked blood vessels that can lead to a heart attack, coronary heart disease, or stroke.
According to the statistics from the CDC, approximately 600,000 Americans die of heart disease every year. The condition is a leading cause of death in both men and women.
Atherosclerosis is a medical condition associated with plaque building up in the arteries, leading to the narrowing of the arterial function in the transportation of oxygenated blood to the heart and other blood of the body.
Plaques are substances made up of the accumulated fat, cholesterol, calcium, and other substances found in the blood, including cadmium.
Long-term accumulation of plaque can also cause hardening and stiffening of arterial walls can lead to the blockage of the arteries and risk of heart disease depending on the location of the blockage.
Most people in the early stage of atherosclerosis do not experience any symptoms. However, as the condition progresses and the location is affected, patients may develop chest pain, shortness of breath, sweating, and anxiety.
The most common causes of atherosclerosis are the imbalance of the ratio of bad cholesterol and good cholesterol in the blood, long-term smoking, obesity, an increase in age, obesity, and some medical conditions, such as diabetes and high blood pressure.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem that is crowded with a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention and treatment of heart disease, researchers examined the effect of effects of 3-(4'-hydroxyl-3',5'-methoxyphenyl)propionic acid (HDMPPA) originating from Korean cabbage on the prevention of atherosclerosis.
The experiments included 21 3-month-old rabbits fed an atherogenic diet containing 0.5% (w/w) cholesterol and 10% (w/w) coconut oil, whereas another two groups were given an atherogenic diet with intravenous injection of either HDMPPA or simvastatin (0.33 mg/kg/day) for 4 weeks.
According to the tested analysis, the HDMPPA injected group not only showed a significant effect on the inhibition of the oxidative modification of low-density lipoprotein (IC 50 = 1.4 microg/mL) but also increased 2,2'-diphenyl-1-picrylhydrazyl radical scavenging activity (IC 50 = 0.78 microg/mL) in a dose-dependent manner.
In hypercholesterolemic rabbits, the thickness of the innermost tunica (layer) of an artery or vein in the HDMPPA group was significantly reduced (control versus HDMPPA, 42%; simvastatin, 38%) without affecting the levels of cholesterol.
Furthermore, the plasma of the HDMPPA group exerted a significantly decreased activity against oxidation compared to that of the control group.
More precisely, HDMPPA also inhibited the generation of vascular reactive oxygen species by inhibiting the levels of cyclooxygenase-2 in the initiation of inflammation.
Based on the findings, researchers said, "HDMPPA prevents the development of aortic atherosclerosis in high-cholesterol-fed rabbits. The antiatherosclerotic effect of HDMPPA may be due to an antioxidative effect at a low dose without cholesterol-lowering effects".
Taken together, Korean cabbage may be considered a supplement for the prevention and treatment of atherosclerosis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid, an active principle of kimchi, inhibits development of atherosclerosis in rabbits by Kim HJ1, Lee JS, Chung HY, Song SH, Suh H, Noh JS, Song YO. (PubMed)
(2) Beneficial effects of polyphenol-rich Olive Oil in patients with early atherosclerosis by RJ Widmer,*,1 MA Freund,*,1 AJ Flammer,1 J Sexton,1 R Lennon,1 A Romani,2 N Mulinacci,2FF Vinceri,2 LO Lerman,1 and A Lerman. (PMC)
The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to supply oxygen and nutrients and remove of metabolic wastes.
Heart disease is a group of medical conditions caused by narrowed or blocked blood vessels that can lead to a heart attack, coronary heart disease, or stroke.
According to the statistics from the CDC, approximately 600,000 Americans die of heart disease every year. The condition is a leading cause of death in both men and women.
Atherosclerosis is a medical condition associated with plaque building up in the arteries, leading to the narrowing of the arterial function in the transportation of oxygenated blood to the heart and other blood of the body.
Plaques are substances made up of the accumulated fat, cholesterol, calcium, and other substances found in the blood, including cadmium.
Long-term accumulation of plaque can also cause hardening and stiffening of arterial walls can lead to the blockage of the arteries and risk of heart disease depending on the location of the blockage.
Most people in the early stage of atherosclerosis do not experience any symptoms. However, as the condition progresses and the location is affected, patients may develop chest pain, shortness of breath, sweating, and anxiety.
The most common causes of atherosclerosis are the imbalance of the ratio of bad cholesterol and good cholesterol in the blood, long-term smoking, obesity, an increase in age, obesity, and some medical conditions, such as diabetes and high blood pressure.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem that is crowded with a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention and treatment of heart disease, researchers examined the effect of effects of 3-(4'-hydroxyl-3',5'-methoxyphenyl)propionic acid (HDMPPA) originating from Korean cabbage on the prevention of atherosclerosis.
The experiments included 21 3-month-old rabbits fed an atherogenic diet containing 0.5% (w/w) cholesterol and 10% (w/w) coconut oil, whereas another two groups were given an atherogenic diet with intravenous injection of either HDMPPA or simvastatin (0.33 mg/kg/day) for 4 weeks.
According to the tested analysis, the HDMPPA injected group not only showed a significant effect on the inhibition of the oxidative modification of low-density lipoprotein (IC 50 = 1.4 microg/mL) but also increased 2,2'-diphenyl-1-picrylhydrazyl radical scavenging activity (IC 50 = 0.78 microg/mL) in a dose-dependent manner.
In hypercholesterolemic rabbits, the thickness of the innermost tunica (layer) of an artery or vein in the HDMPPA group was significantly reduced (control versus HDMPPA, 42%; simvastatin, 38%) without affecting the levels of cholesterol.
Furthermore, the plasma of the HDMPPA group exerted a significantly decreased activity against oxidation compared to that of the control group.
More precisely, HDMPPA also inhibited the generation of vascular reactive oxygen species by inhibiting the levels of cyclooxygenase-2 in the initiation of inflammation.
Based on the findings, researchers said, "HDMPPA prevents the development of aortic atherosclerosis in high-cholesterol-fed rabbits. The antiatherosclerotic effect of HDMPPA may be due to an antioxidative effect at a low dose without cholesterol-lowering effects".
Taken together, Korean cabbage may be considered a supplement for the prevention and treatment of atherosclerosis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid, an active principle of kimchi, inhibits development of atherosclerosis in rabbits by Kim HJ1, Lee JS, Chung HY, Song SH, Suh H, Noh JS, Song YO. (PubMed)
(2) Beneficial effects of polyphenol-rich Olive Oil in patients with early atherosclerosis by RJ Widmer,*,1 MA Freund,*,1 AJ Flammer,1 J Sexton,1 R Lennon,1 A Romani,2 N Mulinacci,2FF Vinceri,2 LO Lerman,1 and A Lerman. (PMC)
Dry Tomato Peel (DTP) Supplementation Inhibits Metabolic Syndrome, Particularly Insulin Resistance, Researchers Say
Kyle J. Norton
Insulin resistance is a condition in which cells that convert glucose to energy in the muscles, body fat, intestine, and liver ignore the signal of the hormone insulin signaling.
In other words, patients with insulin resistance are hyperglycemic. The syndrome is a hallmark of type 2 diabetes.
According to statistics, over 100 million Americans are living with insulin resistance. Approximately 1 in 3, including half of those age 60 and older have a silent blood sugar problem known as insulin resistance.
There are no single causes of insulin resistance, Epidemiologically, aging, ethnicity, overweight or obesity, too much belly fat, physical inactivity, smoking, and certain medical conditions such as Cushing’s disease or polycystic ovary disease are some of the prevalent factors that induce the risk of the condition.
However, most people with some of the aforementioned risk factors have never developed insulin resistance.
The most common symptoms of patients with insulin resistance are tiredness, hunger and difficulty concentrating.
If you have experienced the above symptoms persistently, you may have insulin resistance, please make sure that you check with your doctor to rule out the possibility.
Out of many factors that increase the risk of insulin resistance, some researchers suggested the promotion of a high-fat diet over the past few decades may have a strong and negative impact on the rise of insulin resistance in the US.
Dr. Chad R. Hancock, the lead scientist wrote, "Feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria"
And, "a high-fat diet that raises FFA results in a gradual increase in mitochondria in rat skeletal muscle, with an increase in the capacity for fat oxidation, concomitant with the development of muscle insulin resistance".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
To find healthy food for controlling high blood glucose, researchers examined the effect of dry tomato peel (DTP) on insulin resistance, and atherogenic dyslipidemia induced by a high-saturated fat (HSF) diet in an animal model for 12 weeks.
The study included 40 selected BALB/c male mice (n=40) (8 weeks old, weighing 22.2±1.0 g) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the results from the tested assays, supplementation with DTP not only increased the plasma lycopene concentration and reduced the development of indicators of metabolic syndrome, particularly insulin resistance.
However, hepatic steatosis and inflammation caused by the injection of high-fat diet mice were not reversed with DTP supplementation.
In other words, DTP improved the plasma concentration of lycopene by normalizing the levels of blood glucose in tested mice through its anti-insulin resistance activity.
Dr. Zidani S, the lead scientist said, "Among mice fed the HSF/HC diet, DTP supplementation appears to have a beneficial effect on insulin resistance, which confirms the antiatherogenic effect of DTP".
In vivo, also in high-fat diet (HF)-induced obese mice, tomato vinegar beverage (TVB) at 14 mL kg(-1) body weight for 6 weeks not only inhibited the symptoms associated with fat accumulated in the liver but also promoted glucose tolerance, hyperinsulinemia, and HOMA-IR levels.
Levels of antioxidants in the tested were also significantly improved by TVB. TVB inhibited oxidative stress by significantly increasing glucokinase activity and decreased glucose-6-phosphatase activity in the liver,
More precisely, TVB enhanced glucose metabolism in obese mice. against the onset of insulin resistance.
Based on the findings, researchers wrote, "These results suggest that TVB prevents visceral obesity and insulin resistance via AMPK/PPARα-mediated fatty acid and glucose oxidation (Antioxidant property(TVB)".
Taken together, tomatoes may be considered a dietary supplement for the prevention and treatment of insulin resistance, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice by Seo KI1, Lee J, Choi RY, Lee HI, Lee JH, Jeong YK, Kim MJ, Lee MK. (PubMed)
(3) High-fat diets cause insulin resistance despite an increase in muscle mitochondria by Chad R. Hancock, Dong-Ho Han, May Chen, Shin Terada, Toshihiro Yasuda, David C. Wright,and John O. Holloszy. (PubMed)
Insulin resistance is a condition in which cells that convert glucose to energy in the muscles, body fat, intestine, and liver ignore the signal of the hormone insulin signaling.
In other words, patients with insulin resistance are hyperglycemic. The syndrome is a hallmark of type 2 diabetes.
According to statistics, over 100 million Americans are living with insulin resistance. Approximately 1 in 3, including half of those age 60 and older have a silent blood sugar problem known as insulin resistance.
There are no single causes of insulin resistance, Epidemiologically, aging, ethnicity, overweight or obesity, too much belly fat, physical inactivity, smoking, and certain medical conditions such as Cushing’s disease or polycystic ovary disease are some of the prevalent factors that induce the risk of the condition.
However, most people with some of the aforementioned risk factors have never developed insulin resistance.
The most common symptoms of patients with insulin resistance are tiredness, hunger and difficulty concentrating.
If you have experienced the above symptoms persistently, you may have insulin resistance, please make sure that you check with your doctor to rule out the possibility.
Out of many factors that increase the risk of insulin resistance, some researchers suggested the promotion of a high-fat diet over the past few decades may have a strong and negative impact on the rise of insulin resistance in the US.
Dr. Chad R. Hancock, the lead scientist wrote, "Feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria"
And, "a high-fat diet that raises FFA results in a gradual increase in mitochondria in rat skeletal muscle, with an increase in the capacity for fat oxidation, concomitant with the development of muscle insulin resistance".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
To find healthy food for controlling high blood glucose, researchers examined the effect of dry tomato peel (DTP) on insulin resistance, and atherogenic dyslipidemia induced by a high-saturated fat (HSF) diet in an animal model for 12 weeks.
The study included 40 selected BALB/c male mice (n=40) (8 weeks old, weighing 22.2±1.0 g) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the results from the tested assays, supplementation with DTP not only increased the plasma lycopene concentration and reduced the development of indicators of metabolic syndrome, particularly insulin resistance.
However, hepatic steatosis and inflammation caused by the injection of high-fat diet mice were not reversed with DTP supplementation.
In other words, DTP improved the plasma concentration of lycopene by normalizing the levels of blood glucose in tested mice through its anti-insulin resistance activity.
Dr. Zidani S, the lead scientist said, "Among mice fed the HSF/HC diet, DTP supplementation appears to have a beneficial effect on insulin resistance, which confirms the antiatherogenic effect of DTP".
In vivo, also in high-fat diet (HF)-induced obese mice, tomato vinegar beverage (TVB) at 14 mL kg(-1) body weight for 6 weeks not only inhibited the symptoms associated with fat accumulated in the liver but also promoted glucose tolerance, hyperinsulinemia, and HOMA-IR levels.
Levels of antioxidants in the tested were also significantly improved by TVB. TVB inhibited oxidative stress by significantly increasing glucokinase activity and decreased glucose-6-phosphatase activity in the liver,
More precisely, TVB enhanced glucose metabolism in obese mice. against the onset of insulin resistance.
Based on the findings, researchers wrote, "These results suggest that TVB prevents visceral obesity and insulin resistance via AMPK/PPARα-mediated fatty acid and glucose oxidation (Antioxidant property(TVB)".
Taken together, tomatoes may be considered a dietary supplement for the prevention and treatment of insulin resistance, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice by Seo KI1, Lee J, Choi RY, Lee HI, Lee JH, Jeong YK, Kim MJ, Lee MK. (PubMed)
(3) High-fat diets cause insulin resistance despite an increase in muscle mitochondria by Chad R. Hancock, Dong-Ho Han, May Chen, Shin Terada, Toshihiro Yasuda, David C. Wright,and John O. Holloszy. (PubMed)
#Broccoli and #Tomato #Extract Regulate the Glucose Metabolic Against the Onset of #InsulinResistance, Researchers Say
Kyle J. Norton
Insulin resistance is a hallmark of type 2 diabetes characterized by the inability of the body to use the insulin produced by the pancreas properly.
In other words, signals sent out by the hormone insulin caused by the clog-up of the insulin receptors was ignored by the cell of the muscles, body fat, and liver that process the function to convert glucose into energy.
More precisely, as the clogged-up insulin receptors ignore the signals of the hormone insulin, insulin resistance develops, leading to more production of insulin by the beta cells and over time causing permanent damage to the cells in the pancreas.
Epidemiologically, people with insulin resistance are associated with an increased risk of prediabetes, type 2 diabetes, and chronic conditions such as heart attacks, strokes, and cancer.
A 2016 joint study led by MSA University, suggested that tomato and broccoli extract affects on glucose homeostasis in high-fat diet-induced obesity in rats by regulating the adipocyte hormone Resistin.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Tomato is red, edible fruit, genus Solanum, belongs to the family Solanaceae, native to South America. Because of its health benefits, tomato is grown worldwide for commercial purposes
and often in the greenhouse.
According to the US statistics, approximately, 60 to 70 million individuals are affected by insulin resistance with 40% of individuals older than 50 years may be at risk of insulin resistance.
Believe it or not, the most common risk factors associated with insulin resistance are obesity and hypertension associated with the promotion of a high-fat diet over the past few decades.
Dr. Merat S, the lead scientist wrote, " Contrary to expectation, IR was induced in mice fed the Western diet,,,. The Western diet group had higher average glucose levels (187+/-16 versus 159+/-12 mg/dL) and 4.5-fold higher plasma insulin levels".
A total of 48 male albino rats included in the study were divided into 8 groups as follows: control, HFD, stop fat diet (SD), Tomato 200 mg/kg (T200), Tomato 400 mg/kg (T400), Broccoli 200 mg/kg (B200), Broccoli 400 mg/kg (B400), and Chromax (CX).
According to the tested differentiation after 1 month of treatment,
* Serum levels of resistin were significantly reduced in all groups treated with tomato, broccoli, and CXIn other words, T 200, T 400, B 200, B 400 and CX groups reduced levels of resistin to: 4.13 ± 0.22 ng/ml, 1.51 ± 0.04 ng/ml, 4.13 ± 0.22 ng/ml, 2.32 ± 0.15 ng/ml and 1.37 ± 0.03 ng/ml, compared to the baseline, respectively.
Where resistin is an adipocyte hormone associated with regulating glucose metabolism. Elevated levels of resistin have been found to cause insulin resistance in diabetics.
Increased levels of serum levels of leptin significantly reduced anti-elevated levels of resistin in the T 400 group compared to the B 400 and CX groups.
Additionally, serum levels of adiponectin associated with insulin resistance were significantly increased in the T 400 group (131 ± 3.84 pg/ml).
The results strongly suggested that broccoli and tomato extract inhibited the elevated levels of hormone resistin that cause insulin resistance in the high-fat-diet-induced diabetes animal model.
Based on the finding, researchers said, " tomato and broccoli extract treatment regulates glucose homeostasis via reduction of serum resistin and may be a useful non-pharmacological therapy for obesity".
Taken together, broccoli and tomato extract may be considered supplements for the prevention and treatment of insulin resistance, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats by Aborehab NM1, El Bishbishy MH2, Waly NE. (PubMed)
(2) Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet by Merat S1, Casanada F, Sutphin M, Palinski W, Reaven PD. (PubMed)
Insulin resistance is a hallmark of type 2 diabetes characterized by the inability of the body to use the insulin produced by the pancreas properly.
In other words, signals sent out by the hormone insulin caused by the clog-up of the insulin receptors was ignored by the cell of the muscles, body fat, and liver that process the function to convert glucose into energy.
More precisely, as the clogged-up insulin receptors ignore the signals of the hormone insulin, insulin resistance develops, leading to more production of insulin by the beta cells and over time causing permanent damage to the cells in the pancreas.
Epidemiologically, people with insulin resistance are associated with an increased risk of prediabetes, type 2 diabetes, and chronic conditions such as heart attacks, strokes, and cancer.
A 2016 joint study led by MSA University, suggested that tomato and broccoli extract affects on glucose homeostasis in high-fat diet-induced obesity in rats by regulating the adipocyte hormone Resistin.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Tomato is red, edible fruit, genus Solanum, belongs to the family Solanaceae, native to South America. Because of its health benefits, tomato is grown worldwide for commercial purposes
and often in the greenhouse.
According to the US statistics, approximately, 60 to 70 million individuals are affected by insulin resistance with 40% of individuals older than 50 years may be at risk of insulin resistance.
Believe it or not, the most common risk factors associated with insulin resistance are obesity and hypertension associated with the promotion of a high-fat diet over the past few decades.
Dr. Merat S, the lead scientist wrote, " Contrary to expectation, IR was induced in mice fed the Western diet,,,. The Western diet group had higher average glucose levels (187+/-16 versus 159+/-12 mg/dL) and 4.5-fold higher plasma insulin levels".
A total of 48 male albino rats included in the study were divided into 8 groups as follows: control, HFD, stop fat diet (SD), Tomato 200 mg/kg (T200), Tomato 400 mg/kg (T400), Broccoli 200 mg/kg (B200), Broccoli 400 mg/kg (B400), and Chromax (CX).
According to the tested differentiation after 1 month of treatment,
* Serum levels of resistin were significantly reduced in all groups treated with tomato, broccoli, and CXIn other words, T 200, T 400, B 200, B 400 and CX groups reduced levels of resistin to: 4.13 ± 0.22 ng/ml, 1.51 ± 0.04 ng/ml, 4.13 ± 0.22 ng/ml, 2.32 ± 0.15 ng/ml and 1.37 ± 0.03 ng/ml, compared to the baseline, respectively.
Where resistin is an adipocyte hormone associated with regulating glucose metabolism. Elevated levels of resistin have been found to cause insulin resistance in diabetics.
Increased levels of serum levels of leptin significantly reduced anti-elevated levels of resistin in the T 400 group compared to the B 400 and CX groups.
Additionally, serum levels of adiponectin associated with insulin resistance were significantly increased in the T 400 group (131 ± 3.84 pg/ml).
The results strongly suggested that broccoli and tomato extract inhibited the elevated levels of hormone resistin that cause insulin resistance in the high-fat-diet-induced diabetes animal model.
Based on the finding, researchers said, " tomato and broccoli extract treatment regulates glucose homeostasis via reduction of serum resistin and may be a useful non-pharmacological therapy for obesity".
Taken together, broccoli and tomato extract may be considered supplements for the prevention and treatment of insulin resistance, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats by Aborehab NM1, El Bishbishy MH2, Waly NE. (PubMed)
(2) Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet by Merat S1, Casanada F, Sutphin M, Palinski W, Reaven PD. (PubMed)
#Phytochemical #Lycopene Exerts a Signifcant Effect Against the Risk of #ColorectalCancer, Researchers Suggest
Kyle J. Norton
Colorectal cancer is a chronic condition that causes cell growth irregularly in the tissue of the colon and rectum. In other words, colorectal cancer includes colon and rectal cancer.
The colon and rectum form parts of the digestive system with the function of reabsorbing fluids and processing and secreting waste products from the body.
Most cases of colorectal cancer start in the cells on the surface of the issue of either the colon or rectum. At the very early stage, due to the very small size of the tumor, colorectal cancer may not induce any symptoms.
However, at the advanced stage, the cancerous cells travel may travel a distance away from the colon and rectum to infect other healthy tissue and organ, leading to secondary metastasis.
According to statistics provided by WHO, colorectal cancer is the third most common cancer occurring in men and the second most commonly occurring cancer in women. Over 1.8 million new cases of colorectal cancer were diagnosed in 2018 worldwide.
Out of many prevalent factors associated with the risk of colorectal cancer, some researchers suggested that the rise in the incidence of the disease was linked to the promotion of the Western diet over the past few decades in the US and economic prosperity in Southeast Asia.
More precisely, the increase in colorectal cancer at an alarming rate is a result of replacing the traditional diet with the Western diet due to economic prosperity.
Dr. Alan Moss, the lead scientist wrote, "Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes” by Mehta et al2 helps us to move beyond generalizations about Western diet and CRC risk, to a more detailed understanding of the association between diet and colorectal tumor location and also molecular subtypes".
And, "Processed meats result from salting, smoking, fermenting, or curing the meat, and common examples include ham, bacon, and sausage.5 Furthermore, red meat was declared as probably carcinogenic to humans, and red meat was listed as a group 2A substance.4 Red and processed meats are considered significant components of a “Western” diet".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a plant-based compound for the treatment of colorectal cancer (CRC), researchers examined the effect of lycopene in the risk of colorectal cancer developing.
The study was conducted by searching the studies published in the PubMed and EMBASE medical databases.
According to 15 included in the meta-analysis,
* The comparison of summary relative risk (RR) for the highest versus lowest category, there was no significant association between lycopene consumption and the risk of colorectal cancer.
* However, lycopene consumption showed a significant effect in reducing the risk of colon cancer.
In other words, lycopene not only is associated with the risk of colorectal cancer but also is a phytochemical that processes anti-colon cancer properties.
Additionally, according to the data on lycopene on HT-29 colorectal cancer cells and on animal models studies, injection of lycopene not only inhibited cell proliferation but also the progression of the CRC by interacting with various cellular signaling pathways, including proteins involved in pro-inflammatory production and cell death programming.
More precisely, lycopene suppresses colorectal cancer cells through its antioxidant activity.
Taken altogether, lycopene found in tomato may be considered a supplement for the prevention and treatment of colorectal cancer, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the LKarate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene Consumption and Risk of Colorectal Cancer: A Meta-Analysis of Observational Studies by Wang X1, Yang HH2, Liu Y3, Zhou Q4, Chen ZH. (PubMed)
(2) Colorectal cancer: an update on the effects of lycopene on tumor progression and cell proliferation by Carini F1, David S1, Tomasello G1,2, Mazzola M1,2, Damiani P3, Rappa F1,4, Battaglia L5, Gerges Geagea A1,6, Jurjus R7, Leone A. (PubMed)
(3) The Association Between Diet and Colorectal Cancer Risk: Moving Beyond Generalizations
Alan Moss, and Kumanan Nalankilli. (Gastroenterology)
Colorectal cancer is a chronic condition that causes cell growth irregularly in the tissue of the colon and rectum. In other words, colorectal cancer includes colon and rectal cancer.
The colon and rectum form parts of the digestive system with the function of reabsorbing fluids and processing and secreting waste products from the body.
Most cases of colorectal cancer start in the cells on the surface of the issue of either the colon or rectum. At the very early stage, due to the very small size of the tumor, colorectal cancer may not induce any symptoms.
However, at the advanced stage, the cancerous cells travel may travel a distance away from the colon and rectum to infect other healthy tissue and organ, leading to secondary metastasis.
According to statistics provided by WHO, colorectal cancer is the third most common cancer occurring in men and the second most commonly occurring cancer in women. Over 1.8 million new cases of colorectal cancer were diagnosed in 2018 worldwide.
Out of many prevalent factors associated with the risk of colorectal cancer, some researchers suggested that the rise in the incidence of the disease was linked to the promotion of the Western diet over the past few decades in the US and economic prosperity in Southeast Asia.
More precisely, the increase in colorectal cancer at an alarming rate is a result of replacing the traditional diet with the Western diet due to economic prosperity.
Dr. Alan Moss, the lead scientist wrote, "Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes” by Mehta et al2 helps us to move beyond generalizations about Western diet and CRC risk, to a more detailed understanding of the association between diet and colorectal tumor location and also molecular subtypes".
And, "Processed meats result from salting, smoking, fermenting, or curing the meat, and common examples include ham, bacon, and sausage.5 Furthermore, red meat was declared as probably carcinogenic to humans, and red meat was listed as a group 2A substance.4 Red and processed meats are considered significant components of a “Western” diet".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a plant-based compound for the treatment of colorectal cancer (CRC), researchers examined the effect of lycopene in the risk of colorectal cancer developing.
The study was conducted by searching the studies published in the PubMed and EMBASE medical databases.
According to 15 included in the meta-analysis,
* The comparison of summary relative risk (RR) for the highest versus lowest category, there was no significant association between lycopene consumption and the risk of colorectal cancer.
* However, lycopene consumption showed a significant effect in reducing the risk of colon cancer.
In other words, lycopene not only is associated with the risk of colorectal cancer but also is a phytochemical that processes anti-colon cancer properties.
Additionally, according to the data on lycopene on HT-29 colorectal cancer cells and on animal models studies, injection of lycopene not only inhibited cell proliferation but also the progression of the CRC by interacting with various cellular signaling pathways, including proteins involved in pro-inflammatory production and cell death programming.
More precisely, lycopene suppresses colorectal cancer cells through its antioxidant activity.
Taken altogether, lycopene found in tomato may be considered a supplement for the prevention and treatment of colorectal cancer, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the LKarate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene Consumption and Risk of Colorectal Cancer: A Meta-Analysis of Observational Studies by Wang X1, Yang HH2, Liu Y3, Zhou Q4, Chen ZH. (PubMed)
(2) Colorectal cancer: an update on the effects of lycopene on tumor progression and cell proliferation by Carini F1, David S1, Tomasello G1,2, Mazzola M1,2, Damiani P3, Rappa F1,4, Battaglia L5, Gerges Geagea A1,6, Jurjus R7, Leone A. (PubMed)
(3) The Association Between Diet and Colorectal Cancer Risk: Moving Beyond Generalizations
Alan Moss, and Kumanan Nalankilli. (Gastroenterology)
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