Kyle J. Norton
Scientists may have a pungent spice that processes a potential for the promotion of healthy longevity, according to the study.
Compared to life expectancy which is the average number of years remaining of a given age or living of a certain group of people, longevity is a long life out of the boundary of the life expectancy.
Truly, we all dream of living healthy and with longevity. However how many of us can maintain health and prevent the onset of chronic disease?
Some researchers suggested that by following a healthy lifestyle and moderate exercise healthy longevity can be achieved.
Dr. Mehta N in the study of the healthy lifestyle impact on life expectancy wrote, "Compared to the whole US population, those with such a favorable behavioral profile had a life expectancy at age fifty that was seven years longer, and they experienced a delay in the onset of disability of up to six years".
The results clearly suggested the massively damaging effects caused by unhealthy behavioral risks on health at older ages.
Furthermore, Dr. Vincent Gremeaux and colleagues on the differentiation of exercise and longevity said, "As the number of older individuals continues to increase, it is important to develop interventions that can be easily implemented and contribute to “successful aging”".
And, " In addition to a healthy diet and psychosocial well-being, the benefits of regular exercise on mortality, and the prevention and control of chronic disease affecting both life expectancy and quality of life are well established".
Regularly moderate exercise has been found to have partially reverse effects on the aging process on physiological functions and preserve functional capability in the elderly.
Epidemiological studies strongly suggest that healthy longevity can be achieved by maintaining a minimum quantity and quality of exercise, preventing the development of certain cancers, and lowering the risk of osteoporosis.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a bioactive compound for healthy longevity examined the shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae) activity in the population in the Okinawa Islands of Japan.
According to the review of the literature, culinary shell ginger may contribute to longevity among the population in Okinawa probably due to the procession of phytochemical content with antioxidants and its effects on anti-obesity properties.
Some researchers suggested that the longevity of the population may also be attributed to the shell ginger in the promotion of health in reduced diseases by exhibiting anti-inflammatory, fungistatic, and antibacterial activities against Escherichia coli, Bacillus subtilis, and Bacillus cereus activity.
Shell ginger also is proven to have a positive effect on neuraminidase enzymes and inhibition of human immunodeficiency virus (HIV-1).
Dr. Rolf Teschke in the examination of the mortality rate of Japan's general public compared to the population on the island wrote, "Cardiovascular disease as the top cause of death for both sexes and neoplasms as the second leading cause of death in Japan nationally, with major variations among the prefectures"
And, " Comparing Japan overall with Okinawa, the mean mortality rates from ischaemic heart disease, Alzheimer’s disease, breast cancer, and oesophageal cancer were not remarkably different. However, for Okinawa, four death categories were significantly lower, including ischaemic stroke, stomach cancer, pancreatic cancer, and liver cancer due to hepatitis C.
The finding clearly suggested that the intake of shell ginger which was not found in other areas in Japan may contribute to the healthy longevity of the population in the Okinawa Islands of Japan.
In a joint study led by Woosuk University, Korean scientists evaluated the compound 6-gingerol longevity-promoting activity. isolated from the most active ethyl acetate soluble fraction on Caenorhabditis elegans (C. elegans).
Injection of 6 gingerol elevated the survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The bioactive compound elevated the antioxidant enzyme activities of C. elegans and showed a dose-dependent reduction of intracellular reactive oxygen species (ROS) accumulation in worms.
Furthermore, 6 gingerols also demonstrated increased stress tolerance, leading to the promotion of stress resistance proteins.
The findings strongly suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.
Taken together, ginger and shell ginger may be considered functional foods for the promotion of healthy longevity with no side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 and Dae Keun Kim. (PubMed)
(2) Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet) for Human Longevity in Okinawa, Japan? by Rolf Teschke1,* and Tran Dang Xuan. (PMC)
(3) The Population Health Benefits Of A Healthy Lifestyle: Life Expectancy Increased And Onset Of Disability Delayed by Mehta N1, Myrskylä M. (PubMed)
(4) Exercise and longevity by Vincent Gremeaux, Duxabcdef, MathieuGay, RomualdLeperse, Philippe Sosneraghi, MartinJuneau, AnilNigam. (Science Direct)
Wednesday, 23 August 2023
#Fennel Essential Oil and Extract Process a Strong #Hypoglycemic Activity, Scientists Reveal
Kyle J. Norton
Fennel may have a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found. In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.
Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.
Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick, or high levels of stress in patients with diabetes also can cause blood glucose uptake.
Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.
Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections
Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean
The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and anti-depression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the examination of the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.
At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.
The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.
After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.
Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.
However, the injection of fennel extract exhibited the highest toxicity.
These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.
Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that
* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.
* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.
* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.
This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.
Taken together, fennel extract and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)
Fennel may have a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found. In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.
Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.
Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick, or high levels of stress in patients with diabetes also can cause blood glucose uptake.
Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.
Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections
Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean
The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and anti-depression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the examination of the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.
At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.
The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.
After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.
Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.
However, the injection of fennel extract exhibited the highest toxicity.
These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.
Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that
* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.
* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.
* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.
This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.
Taken together, fennel extract and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)
#Healthyfood #Cranberry #Proanthocyanidin (cPAC) Processes Anti Microbial and Antibiotic Resistance Activity, Scientists Say
Kyle J. Norton
Antibiotics are a group of conventional medicines used for the treatment of bacterial, fungal parasitic,... infections.
The medications have no effects on viral infection.
Infection is a disease caused by microorganism invasion.
After entering the body, the organisms selectively find a specific tissue or organ to start their multiplication.
Most infectious diseases can be passed from infected person to person or transmitted by bites from insects or animals.
However, acquired infectious diseases can also be caused by ingesting contaminated food or water or being exposed to organisms in the environment.
Most organisms before having a chance to induce infection are killed off by the immune system response in the acute phase of infection, by stimulating the production of a proinflammatory cytokine.
Unfortunately, if the immune system fails to destroy the invasive organism within a set period of time, normally in a few weeks, it will adapt to the change, causing chronic infection.
Antibiotics have been found to cause digestive discomforts such as nausea, and indigestion. vomiting, diarrhea, and bloating. the feeling of fullness, loss of appetite, and stomach cramping or pain, acutely.
Chronic use of antibiotics also induces more serious adverse effects, including skin rash, skin allergic reactions, upset stomach, and fungal (yeast) vaginal infections or oral thrush by weakening the immune system.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound for the treatment of infectious diseases, researchers investigated the antibacterial activity of cranberry proanthocyanidin (cPAC) on resistance to tetracycline in Escherichia coli and Pseudomonas aeruginosa.
According to the tested assays, cPAC exerted a potentiating effect, both in vitro and in vivo, on a broad range of antibiotic classes against pathogenic E. coli, Proteus mirabilis, and P. aeruginosa.
cPAC demonstrated the antibacterial effect through two antibiotic resistance mechanisms, namely, selective membrane permeability, and multidrug efflux pumps.
Based on the evidence, researchers said, " The use of cPAC to potentiate antibiotics and mitigate the development of resistance could improve treatment outcomes and help combat the growing threat of antibiotic resistance".
Taken together, cranberry may be considered an adjunct therapy as an antibiotic against bacterial pathogens, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Proanthocyanidin Interferes with Intrinsic Antibiotic Resistance Mechanisms of Gram-Negative Bacteria by Maisuria VB1, Okshevsky M1, Déziel E2, Tufenkji N. (PubMed)
Antibiotics are a group of conventional medicines used for the treatment of bacterial, fungal parasitic,... infections.
The medications have no effects on viral infection.
Infection is a disease caused by microorganism invasion.
After entering the body, the organisms selectively find a specific tissue or organ to start their multiplication.
Most infectious diseases can be passed from infected person to person or transmitted by bites from insects or animals.
However, acquired infectious diseases can also be caused by ingesting contaminated food or water or being exposed to organisms in the environment.
Most organisms before having a chance to induce infection are killed off by the immune system response in the acute phase of infection, by stimulating the production of a proinflammatory cytokine.
Unfortunately, if the immune system fails to destroy the invasive organism within a set period of time, normally in a few weeks, it will adapt to the change, causing chronic infection.
Antibiotics have been found to cause digestive discomforts such as nausea, and indigestion. vomiting, diarrhea, and bloating. the feeling of fullness, loss of appetite, and stomach cramping or pain, acutely.
Chronic use of antibiotics also induces more serious adverse effects, including skin rash, skin allergic reactions, upset stomach, and fungal (yeast) vaginal infections or oral thrush by weakening the immune system.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound for the treatment of infectious diseases, researchers investigated the antibacterial activity of cranberry proanthocyanidin (cPAC) on resistance to tetracycline in Escherichia coli and Pseudomonas aeruginosa.
According to the tested assays, cPAC exerted a potentiating effect, both in vitro and in vivo, on a broad range of antibiotic classes against pathogenic E. coli, Proteus mirabilis, and P. aeruginosa.
cPAC demonstrated the antibacterial effect through two antibiotic resistance mechanisms, namely, selective membrane permeability, and multidrug efflux pumps.
Based on the evidence, researchers said, " The use of cPAC to potentiate antibiotics and mitigate the development of resistance could improve treatment outcomes and help combat the growing threat of antibiotic resistance".
Taken together, cranberry may be considered an adjunct therapy as an antibiotic against bacterial pathogens, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Proanthocyanidin Interferes with Intrinsic Antibiotic Resistance Mechanisms of Gram-Negative Bacteria by Maisuria VB1, Okshevsky M1, Déziel E2, Tufenkji N. (PubMed)
#TomatoPowder TP Decreasea the Rate of Aberrant Crypt Foci Associated with Early Onset of #ColorectalCancer, Researchers Say
Kyle J. Norton
Colorectal cancer is a medical condition caused by irregular cell growth in the tissues of the colon or rectum.
Most cases of colorectal cancer start in the cell on the surface of the inner lining of the colon or rectum, before penetrating into the deeper layer to induce localized tumors.
At the very early stage of colorectal cancer, most patients are asymptomatic due to the very size of the tumor which does not affect the function of the colon or rectum. However, at the advanced stage, the oversize tumor can press on the nearby blood vessels and nerves and affect the organ's functioning, leading to severe pain and bleeding and specific symptoms accompanied by the general symptoms shared by other types of cancer.
At this stage, cancer cells can also travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
According to the statistics provided by the American Cancer Society, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. Proximately, in 2019, 101,420 new cases of colon cancer and 44,180 rectal cancer will be diagnosed.
The lifetime risk of developing colorectal cancer is about 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
The 5-year survival rate of people with localized stage colorectal cancer is 90%. However, only 39% of patients are diagnosed at an early stage.
Out of many risk factors associated with the onset of colorectal cancer, some researchers suggested that the widespread of colorectal cancer in South Korea may be correlated with the promotion of a high-fat diet over the past few decades, particularly in men.
Dr. Kim, Jeehyun, wrote, "In men, total fat intake was not associated with risk of colorectal adenoma. However, the risk of colorectal adenoma increases with higher saturated fatty acid (SFA) intake. The adjusted odds ratio in the highest quintile was 1.71 (95% confidence interval, 1.01–2.91) compared with that in the lowest quintile".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to find a potential compound for the treatment of colon cancer, researchers investigated the effects of tomato powder (TP) on the development of azoxymethane (AOM)-induced colorectal cancer in Wistar rats.
According to the tested assays, TP added to feed at a 5% rate decreased the rate of aberrant crypt foci (ACF) associated with the early stage of colon cancer development and reduced the development of adenocarcinoma and growth of AOM-induced colorectal cancer in rats.
TP supplementation also demonstrated chemopreventive activities against the protein involved in the stimulating production of proinflammatory cytokines in the colon tissues and promoted cancer cell apoptosis.
Based on the findings, Dr. Tuzcu M, the lead scientist wrote, "Our findings identify an intimate connection between dietary supplementation of TP and the decreased risk of colorectal cancer in rats".
And "suggest that consumption of TP would be a natural candidate for the prevention of colorectal cancer in men".
Furthermore, according to the joint study led by the University of Almería, tomatoes showed significant time- and concentration-dependent inhibitory/cytotoxic effects on HT-29 cells.
Moreover, adding tomato carotenoids and olive oil to HT-29 cells in cultures demonstrated a better inhibitory effect compared to the application of individual compounds in CCD-18 normal cells.
In variety comparison, the Racimo tomato displayed the most anti-cancer activity against colorectal cancer cell proliferation compared to others, without affecting the normal CCD-18 cells.
In chemical analysis, olive oil and tomato carotenoids inhibited the HT-29 cancer cell proliferation synergistically compared to no effect of other phenolic compounds.
Taken together, tomatoes alone or combined with olive oil may be considered supplements for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-κB and regulating Nrf2/HO-1 pathway by Tuzcu M1, Aslan A, Tuzcu Z, Yabas M, Bahcecioglu IH, Ozercan IH, Kucuk O, Sahin K. (PubMed)
(2) Phytochemical composition and in vitro anti-tumor activities of selected tomato varieties by Ramos-Bueno RP1, Romero-González R2, González-Fernández MJ1, Guil-Guerrero JL. (PubMed)
(3) Association between dietary fat intake and colorectal adenoma in Korean adults
A cross-sectional study by Kim, Jeehyun, MD; Oh, Seung-Won, MD, MBA, PhD; Kim, Young-Sun, MD, PhD; Kwon, Hyuktae, MD, MPH, Ph.D.; Joh, Hee-Kyung, MD, MPH, PhD; Lee, Ji-Eun, MD; Park, Danbee, MD; Park, Jae-Hong, MD; Ko, Ah-Ryoung, MD; Kim, Ye-Ji, MD. (Medicine)
Colorectal cancer is a medical condition caused by irregular cell growth in the tissues of the colon or rectum.
Most cases of colorectal cancer start in the cell on the surface of the inner lining of the colon or rectum, before penetrating into the deeper layer to induce localized tumors.
At the very early stage of colorectal cancer, most patients are asymptomatic due to the very size of the tumor which does not affect the function of the colon or rectum. However, at the advanced stage, the oversize tumor can press on the nearby blood vessels and nerves and affect the organ's functioning, leading to severe pain and bleeding and specific symptoms accompanied by the general symptoms shared by other types of cancer.
At this stage, cancer cells can also travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
According to the statistics provided by the American Cancer Society, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. Proximately, in 2019, 101,420 new cases of colon cancer and 44,180 rectal cancer will be diagnosed.
The lifetime risk of developing colorectal cancer is about 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
The 5-year survival rate of people with localized stage colorectal cancer is 90%. However, only 39% of patients are diagnosed at an early stage.
Out of many risk factors associated with the onset of colorectal cancer, some researchers suggested that the widespread of colorectal cancer in South Korea may be correlated with the promotion of a high-fat diet over the past few decades, particularly in men.
Dr. Kim, Jeehyun, wrote, "In men, total fat intake was not associated with risk of colorectal adenoma. However, the risk of colorectal adenoma increases with higher saturated fatty acid (SFA) intake. The adjusted odds ratio in the highest quintile was 1.71 (95% confidence interval, 1.01–2.91) compared with that in the lowest quintile".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to find a potential compound for the treatment of colon cancer, researchers investigated the effects of tomato powder (TP) on the development of azoxymethane (AOM)-induced colorectal cancer in Wistar rats.
According to the tested assays, TP added to feed at a 5% rate decreased the rate of aberrant crypt foci (ACF) associated with the early stage of colon cancer development and reduced the development of adenocarcinoma and growth of AOM-induced colorectal cancer in rats.
TP supplementation also demonstrated chemopreventive activities against the protein involved in the stimulating production of proinflammatory cytokines in the colon tissues and promoted cancer cell apoptosis.
Based on the findings, Dr. Tuzcu M, the lead scientist wrote, "Our findings identify an intimate connection between dietary supplementation of TP and the decreased risk of colorectal cancer in rats".
And "suggest that consumption of TP would be a natural candidate for the prevention of colorectal cancer in men".
Furthermore, according to the joint study led by the University of Almería, tomatoes showed significant time- and concentration-dependent inhibitory/cytotoxic effects on HT-29 cells.
Moreover, adding tomato carotenoids and olive oil to HT-29 cells in cultures demonstrated a better inhibitory effect compared to the application of individual compounds in CCD-18 normal cells.
In variety comparison, the Racimo tomato displayed the most anti-cancer activity against colorectal cancer cell proliferation compared to others, without affecting the normal CCD-18 cells.
In chemical analysis, olive oil and tomato carotenoids inhibited the HT-29 cancer cell proliferation synergistically compared to no effect of other phenolic compounds.
Taken together, tomatoes alone or combined with olive oil may be considered supplements for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-κB and regulating Nrf2/HO-1 pathway by Tuzcu M1, Aslan A, Tuzcu Z, Yabas M, Bahcecioglu IH, Ozercan IH, Kucuk O, Sahin K. (PubMed)
(2) Phytochemical composition and in vitro anti-tumor activities of selected tomato varieties by Ramos-Bueno RP1, Romero-González R2, González-Fernández MJ1, Guil-Guerrero JL. (PubMed)
(3) Association between dietary fat intake and colorectal adenoma in Korean adults
A cross-sectional study by Kim, Jeehyun, MD; Oh, Seung-Won, MD, MBA, PhD; Kim, Young-Sun, MD, PhD; Kwon, Hyuktae, MD, MPH, Ph.D.; Joh, Hee-Kyung, MD, MPH, PhD; Lee, Ji-Eun, MD; Park, Danbee, MD; Park, Jae-Hong, MD; Ko, Ah-Ryoung, MD; Kim, Ye-Ji, MD. (Medicine)
#Beta-Sitosterol BSS Inhibits Parameters Associated with the Onset of #Hypertension, Researchers Suggest
Kyle J. Norton
Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.
Hypertension or high blood pressure is a condition characterized by persistently or abnormally high blood pressure that leads to rising pressure in your heart.
It also is a member of the cluster of metabolic syndrome associated with the risk of diabetes and cardiovascular disease.
High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.
If the pressure stays high over time it can cause hardening and stiffening of the arterial wall,, a major risk factor of heart diseases.
The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.
In the US approximately, one-third of the adults have high blood pressure, affecting over 77 million people in the country.
Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.
High blood pressure can be acute or chronic. Acute high blood pressure most often occurs in people with sudden stress or intense physical exercise. As the heart must pump harder to provide the needs of nutrients and oxygen.
Most cases of chronic high blood pressure are associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.
If you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belonging to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the prevention and treatment of metabolic syndrome, researchers compared the effects of β-sitosterol (BSS) and lisinopril, antihypertension in rats.
According to the tested analysis of rat groups induced hypertension by cadmium chloride treated by BSS and lisinopril, * BSS showed a significant decrease (p<0.05) in the serum creatinine concentration, compared to hypertensive rats.
* Lisinopril treatment showed a significant increase (p<0.05) in the activity of oxidative stress markers AST and ALP, compared to normal rats.
* Treatment of with BSS and lisinopril showed slight variations in the concentration of serum electrolytes compared with normal and hypertensive rats.
* BSS significantly reduced calcium levels compared with the hypertensive group in the activation of oxidative stress.
Based on the findings, researchers said, "The study shows that BSS is effective in restoring basal liver and kidney functions in hypertensive rats.
Taken altogether, beta-sitosterol may be considered a supplement for the protection of liver and kidney functioning, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Ameliorative effects of β-sitosterol on some biochemical indices of hypertension in Wistar albino rats by Olaiya CO1, Esan AM1, Alabi TD. (PubMed)
Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.
Hypertension or high blood pressure is a condition characterized by persistently or abnormally high blood pressure that leads to rising pressure in your heart.
It also is a member of the cluster of metabolic syndrome associated with the risk of diabetes and cardiovascular disease.
High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.
If the pressure stays high over time it can cause hardening and stiffening of the arterial wall,, a major risk factor of heart diseases.
The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.
In the US approximately, one-third of the adults have high blood pressure, affecting over 77 million people in the country.
Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.
High blood pressure can be acute or chronic. Acute high blood pressure most often occurs in people with sudden stress or intense physical exercise. As the heart must pump harder to provide the needs of nutrients and oxygen.
Most cases of chronic high blood pressure are associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.
If you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belonging to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the prevention and treatment of metabolic syndrome, researchers compared the effects of β-sitosterol (BSS) and lisinopril, antihypertension in rats.
According to the tested analysis of rat groups induced hypertension by cadmium chloride treated by BSS and lisinopril, * BSS showed a significant decrease (p<0.05) in the serum creatinine concentration, compared to hypertensive rats.
* Lisinopril treatment showed a significant increase (p<0.05) in the activity of oxidative stress markers AST and ALP, compared to normal rats.
* Treatment of with BSS and lisinopril showed slight variations in the concentration of serum electrolytes compared with normal and hypertensive rats.
* BSS significantly reduced calcium levels compared with the hypertensive group in the activation of oxidative stress.
Based on the findings, researchers said, "The study shows that BSS is effective in restoring basal liver and kidney functions in hypertensive rats.
Taken altogether, beta-sitosterol may be considered a supplement for the protection of liver and kidney functioning, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Ameliorative effects of β-sitosterol on some biochemical indices of hypertension in Wistar albino rats by Olaiya CO1, Esan AM1, Alabi TD. (PubMed)
#Healthyfood #Honey For the Treatment of #Eczematous Ear Disease With No Side Effects, Scientists Say
Kyle J. Norton
In seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.
Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.
However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.
The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.
Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case that the disease may take weeks or months to recover.
Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention severe ear pain, and temporary loss of hearing, due to building up thick and dry skin can build up inside the ear canal, leading to narrowing the ear canal.
Untreated chronic otitis externa can cause deafness.
Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs.
Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.
Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.
According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops treatment of eczematous external otitis.
15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks.
Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.
Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, they did not eradicate Staphylococcus aureus infection.
Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.
Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".
Taken together, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. (PubMed)
(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (PubMed)
(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (AAFP)
In seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.
Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.
However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.
The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.
Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case that the disease may take weeks or months to recover.
Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention severe ear pain, and temporary loss of hearing, due to building up thick and dry skin can build up inside the ear canal, leading to narrowing the ear canal.
Untreated chronic otitis externa can cause deafness.
Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs.
Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.
Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.
According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.
Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.
The liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweeteners by many people.
In finding a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops treatment of eczematous external otitis.
15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks.
Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.
Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, they did not eradicate Staphylococcus aureus infection.
Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.
Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".
Taken together, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. (PubMed)
(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (PubMed)
(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (AAFP)
Tuesday, 22 August 2023
#Ursolicacid Isolated From #Herbal #Arctostaphylos uva-ursi Processes Anti=#GastricCancer Activity, Researchers Show
Kyle J. Norton
Scientists may have found a herbal remedy for the prevention and treatment of gastric cancer with no side effects, according to studies.
Gastric cancer or stomach cancer is a condition characterized by the abnormal growth of cells in the stomach tissue.
Most cases of gastric cancer start in the cells on the surface of the inner lining of the stomach tissue.
At stage 0, due to the gastric cancer cells being restricted or completely contained within the innermost layer of the lining, patients may not experience any symptoms.
However, at the later stage, the cancer cells can travel a distance away from the stomach to infect other tissue and organ, leading to secondary metastasis. If the tumor grows large enough, it may suppress the nearby blood vessels and nerve cells, causing blood to leak into the stomach and localized severe pain.
Besides common symptoms of cancers, patients with gastric cancer also experience some specific symptoms such as persistent abdominal (belly) pain., vague discomfort in the abdomen, a sense of fullness in the upper abdomen after eating a small meal, and heartburn or indigestion.
If you are having some of the above symptoms, please check with your doctor to rule out gastric cancer possibility.
Although there are many risk factors involved in the onset of the disease, such as family history, Helicobacter pylori infection, smoking, genetic preposition, certain stomach conditions, previous stomach surgery and type A blood, some researchers suggested that the most common cause of gastric cancer in the Western world is the Western diet-related disease.
Dr. Bertuccio P, the lead scientist at the Istituto di Ricerche Farmacologiche Mario Negri, in the concern of diet pattern in the risk of gastric cancer, wrote, " An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89)" and "A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category".
The results strongly indicated the risk of gastric cancer is substantially higher in the Western diet group compared to the lower risk of a healthy diet.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb plant has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infections, kidney stones, pelvic pain, etc.
The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
With an aim to find a natural ingredient or whole food for the treatment of gastric cancer, researchers at the Shanghai University of Traditional Chinese Medicine examined the effects of ursolic acid isolated from bearberry (Arctostaphylos uva-ursi) against the pathogenesis of gastric cancer characterized by excessive proliferation, abnormal differentiation, and reduced apoptosis.
Ursolic acid, extracted from the traditional Chinese medicine bearberry, inhibited gastric cancer cell proliferation and induced apoptosis.
Further assessment of anti-gastric cancer, researchers discovered that ursolic acid exhibited apoptotic activity through cancer cell degradation observed in the gastric cancer BGC-823 cells.
In other words, efficacy is associated with a translocation of cofilin-1 protein that activates the function of cytochrome c in programmed cell death from the mitochondria to the cytoplasm.
These results suggested that ursolic acid activated the function of proteins (the caspase cascade) associated with the cell death and apoptotic pathway.
Where Mitochondria are the major organelles involved in the biochemical execution of apoptosis
Dr. the lead scientist, after taking into account co and confounders said, "Mitochondrial translocation of cofilin-1 might play a crucial role in the promotion of apoptosis and might be a key target for future treatment of human gastric cancer".
Taken together, Bearberry (herbal Arctostaphylos uva-ursi) processed a major compound of ursolic acid may be considered a functional remedy for the prevention and combined with other primary medicine for the treatment of gastric cancer, pending the confirmation of large sample size and multicenter human study.
However, intake of ursolic acid as a supplement should be taken with extreme care to prevent overdoses and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid by Tang Q, Ji Q, Tang Y, Chen T, Pan G, Hu S, Bao Y, Peng W, Yin P.(PubMed)
(2) Dietary patterns and gastric cancer risk: a systematic review and meta-analysis by Bertuccio P1, Rosato V, Andreano A, Ferraroni M, Decarli A, Edefonti V, La Vecchia C. (PubMed)
Scientists may have found a herbal remedy for the prevention and treatment of gastric cancer with no side effects, according to studies.
Gastric cancer or stomach cancer is a condition characterized by the abnormal growth of cells in the stomach tissue.
Most cases of gastric cancer start in the cells on the surface of the inner lining of the stomach tissue.
At stage 0, due to the gastric cancer cells being restricted or completely contained within the innermost layer of the lining, patients may not experience any symptoms.
However, at the later stage, the cancer cells can travel a distance away from the stomach to infect other tissue and organ, leading to secondary metastasis. If the tumor grows large enough, it may suppress the nearby blood vessels and nerve cells, causing blood to leak into the stomach and localized severe pain.
Besides common symptoms of cancers, patients with gastric cancer also experience some specific symptoms such as persistent abdominal (belly) pain., vague discomfort in the abdomen, a sense of fullness in the upper abdomen after eating a small meal, and heartburn or indigestion.
If you are having some of the above symptoms, please check with your doctor to rule out gastric cancer possibility.
Although there are many risk factors involved in the onset of the disease, such as family history, Helicobacter pylori infection, smoking, genetic preposition, certain stomach conditions, previous stomach surgery and type A blood, some researchers suggested that the most common cause of gastric cancer in the Western world is the Western diet-related disease.
Dr. Bertuccio P, the lead scientist at the Istituto di Ricerche Farmacologiche Mario Negri, in the concern of diet pattern in the risk of gastric cancer, wrote, " An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89)" and "A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category".
The results strongly indicated the risk of gastric cancer is substantially higher in the Western diet group compared to the lower risk of a healthy diet.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb plant has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infections, kidney stones, pelvic pain, etc.
The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
With an aim to find a natural ingredient or whole food for the treatment of gastric cancer, researchers at the Shanghai University of Traditional Chinese Medicine examined the effects of ursolic acid isolated from bearberry (Arctostaphylos uva-ursi) against the pathogenesis of gastric cancer characterized by excessive proliferation, abnormal differentiation, and reduced apoptosis.
Ursolic acid, extracted from the traditional Chinese medicine bearberry, inhibited gastric cancer cell proliferation and induced apoptosis.
Further assessment of anti-gastric cancer, researchers discovered that ursolic acid exhibited apoptotic activity through cancer cell degradation observed in the gastric cancer BGC-823 cells.
In other words, efficacy is associated with a translocation of cofilin-1 protein that activates the function of cytochrome c in programmed cell death from the mitochondria to the cytoplasm.
These results suggested that ursolic acid activated the function of proteins (the caspase cascade) associated with the cell death and apoptotic pathway.
Where Mitochondria are the major organelles involved in the biochemical execution of apoptosis
Dr. the lead scientist, after taking into account co and confounders said, "Mitochondrial translocation of cofilin-1 might play a crucial role in the promotion of apoptosis and might be a key target for future treatment of human gastric cancer".
Taken together, Bearberry (herbal Arctostaphylos uva-ursi) processed a major compound of ursolic acid may be considered a functional remedy for the prevention and combined with other primary medicine for the treatment of gastric cancer, pending the confirmation of large sample size and multicenter human study.
However, intake of ursolic acid as a supplement should be taken with extreme care to prevent overdoses and acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid by Tang Q, Ji Q, Tang Y, Chen T, Pan G, Hu S, Bao Y, Peng W, Yin P.(PubMed)
(2) Dietary patterns and gastric cancer risk: a systematic review and meta-analysis by Bertuccio P1, Rosato V, Andreano A, Ferraroni M, Decarli A, Edefonti V, La Vecchia C. (PubMed)
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