Kyle J. Norton
Inflammatory bowel disease (IBD) is a class of chronic conditions associated with the inflammation of the gastrointestinal tract, including
* Ulcerative colitis is a chronic inflammation and ulcers found in the innermost lining of the colon and rectum.
* Crohn's disease. is a type of IBD that causes inflammation of the lining of the digestive tract, other than the colon and rectum.
The most common symptoms of IBD are severe diarrhea, abdominal pain, fatigue, and weight loss. Long-term persistent symptoms such as weight loss may be life-threatening.
If you have experienced some of the aforementioned symptoms, please make sure to check with your doctor to rule out the possibility.
The causes of IBD are unknown. However, some researchers suggested that the promotion of a high-fat diet over the past few decades that caused the alternation of the ratio of gut microbiota may be the major culprit in facilitating the onset of IBD.
The research of Case Western Reserve University, wrote, "A high-fat diet may lead to specific changes in gut bacteria that could fight harmful inflammation -- a major discovery for patients suffering from Crohn's disease, research indicates. Crohn's disease, a type of inflammatory bowel syndrome, causes debilitating intestinal swelling, cramping, and diarrhea".
Betanin is a phytochemical in the class of red and yellow indole-derived pigments of betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find a treatment for inflammatory bowel disease (IBS), researchers examined the effect of beetroot (Beta vulgaris var. Rubra) products and their major component betanin on the reactive oxygen species (ROS) production and DNA damage in vitro.
In neutrophils isolated from the blood of patients with inflammatory bowel disease--ulcerative colitis (UC) and Crohn's disease (CD), injection of betanin at 100 μM for 24 h increased DNA damage, according to the comet assay.
However, in Caco-2 cells. injection of betanin at 100 μM for 24 h showed a lesser pronounced stimulation of DNA damage.
Treatment of Caco-2 cells with H2O2 caused a 4-fold increase of DNA strand breaks in comparison to untreated cells, but pre-treatment with betanin reduced DNA damage in these cells.
In other words, betanin exerted a cytotoxic effect against the DNA alternated cells but inhibited the free radical expression in the induction of DNA damage in normal cells.
More precisely, betanin led to the release of ROS and apoptotic cell death.
Based on the findings, researchers wrote, " betanin may exert anti-inflammatory and potentially cancer-preventive activity".
Taken altogether, betanin may be considered a supplement for the prevention and treatment of inflammatory bowel disease, pending the confirmation of a larger sample size and multicenter human study.
Intake of betanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) DNA damage and apoptosis in blood neutrophils of inflammatory bowel disease patients and in Caco-2 cells in vitro exposed to betanin by Zielińska-Przyjemska M1, Olejnik A2, Dobrowolska-Zachwieja A3, Łuczak M4, Baer-Dubowska W. (PubMed)
(2) High fat diet reduces gut bacteria, and Crohn's disease symptoms by Case Western Reserve University. (Science Daily)
Wednesday, 23 August 2023
#Pintobeans Inhibit Markers and Gene Associated with the Levels of #Cholesterol, Researchers Find
Kyle J. Norton
Cholesterol is a waxy substance carried around by lipoproteins, that do not mix with water-based blood in our body.
Cholesterol is needed for our body to build cell walls make hormones and vitamin D, and create bile salts that help to digest fat, particularly in the building of strong cell membranes. However, too much of it can be dangerous because cholesterol cannot dissolve in your blood.
There are 2 types of cholesterol. The low-density lipoprotein is also known as bad cholesterol which performs the aforementioned activity in the right levels and the high-density lipoprotein which returns cholesterol back to the liver for reuse.
However, overexpression of cholesterol can cause plaque building up on the arterial wall, leading to arterial narrowing, wall stiffness, and hardening, some major causes of heart disease and stroke.
Although high blood cholesterol does not induce any symptoms, a prolonged period of uncontrolled high blood cholesterol can cause complications of chest pain, the early signs of coronary artery disease, heart attack,.... and stroke.
According to medical guidelines, the normal goal of non-HDL cholesterol levels should be 30 mg/dL higher than the LDL cholesterol level.
For example, if your non-HDL cholesterol level is LDL cholesterol 30 mg/dL = 130 mg/dL and your HDL is 40 mg/dL = Non-HDL-c/HDL-c ratio of 3.25, the ideal range of the ratio.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lower than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
On finding a natural ingredient for the prevention and treatment of diseases associated with high blood cholesterol, scientists examined the changes in cholesterol metabolism in response to whole pinto beans (wPB) and their hulls (hPB) supplemented into a diet rich in saturated fat in hamsters.
The pinto bean is also known as the common bean, genus Phaseolus, and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish-beige background, thus appearing painted or spotted.
The study included forty-four 9-wk-old male Golden Syrian hamsters that were randomly assigned to 4 diet groups (n = 11), including a 5% (wt:wt) fat diet [normal-fat diet (NF)], a 15% (wt:wt) fat diet [diet rich in saturated fat (HSF), saturated fatty acids accounted for 70% of total fatty acids], or HSF supplemented with 5% (wt:wt) wPB or 0.5% (wt:wt) hPB for 4 wk.
According to the plasma, liver, intestinal, and fecal samples that were collected to evaluate multiple cholesterol markers and gene targets,
* The plasma non-high-density lipoprotein (non-HDL) concentration was significantly reduced in the wPB- and hPB-supplemented groups by 31.9 ± 3.5% and 53.6 ± 3.2%, respectively, compared to the HSF group (P < 0.01), to concentrations comparable with the NF group
* The wPB-supplemented hamsters had significantly lower liver cholesterol (45.1%, P < 0.001) and higher fecal cholesterol concentrations (94.8%, P = 0.001) than those of the HSF group.
* The expressions of hepatic 3-hydroxy-3-methylglutaryl CoA reductase (Hmgcr) and small intestinal acyl-coenzyme A: cholesterol acyltransferase 2 (Acat2) associated with the elevation of blood cholesterol were significantly decreased in animals administered wPB (by 89.1% and 63.8%, respectively) and hPB (by 72.9% and 47.7%, respectively) compared to the HSF-fed counterparts (P < 0.05).
Based on the results, researchers suggest, "Pinto beans remediated high cholesterol induced by HSF in male hamsters by decreasing hepatic cholesterol synthesis and intestinal cholesterol absorption, effects which were partially exerted by the hulls".
Taken altogether, Pinto beans may be considered s functional for the treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pinto Beans (Phaseolus vulgaris L.) Lower Non-HDL Cholesterol in Hamsters Fed a Diet Rich in Saturated Fat and Act on Genes Involved in Cholesterol Homeostasis by Nguyen AT1,2, Althwab S3,4, Qiu H3, Zbasnik R1, Urrea C5, Carr TP3, Schlegel V. (PubMed)
Cholesterol is a waxy substance carried around by lipoproteins, that do not mix with water-based blood in our body.
Cholesterol is needed for our body to build cell walls make hormones and vitamin D, and create bile salts that help to digest fat, particularly in the building of strong cell membranes. However, too much of it can be dangerous because cholesterol cannot dissolve in your blood.
There are 2 types of cholesterol. The low-density lipoprotein is also known as bad cholesterol which performs the aforementioned activity in the right levels and the high-density lipoprotein which returns cholesterol back to the liver for reuse.
However, overexpression of cholesterol can cause plaque building up on the arterial wall, leading to arterial narrowing, wall stiffness, and hardening, some major causes of heart disease and stroke.
Although high blood cholesterol does not induce any symptoms, a prolonged period of uncontrolled high blood cholesterol can cause complications of chest pain, the early signs of coronary artery disease, heart attack,.... and stroke.
According to medical guidelines, the normal goal of non-HDL cholesterol levels should be 30 mg/dL higher than the LDL cholesterol level.
For example, if your non-HDL cholesterol level is LDL cholesterol 30 mg/dL = 130 mg/dL and your HDL is 40 mg/dL = Non-HDL-c/HDL-c ratio of 3.25, the ideal range of the ratio.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lower than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
On finding a natural ingredient for the prevention and treatment of diseases associated with high blood cholesterol, scientists examined the changes in cholesterol metabolism in response to whole pinto beans (wPB) and their hulls (hPB) supplemented into a diet rich in saturated fat in hamsters.
The pinto bean is also known as the common bean, genus Phaseolus, and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish-beige background, thus appearing painted or spotted.
The study included forty-four 9-wk-old male Golden Syrian hamsters that were randomly assigned to 4 diet groups (n = 11), including a 5% (wt:wt) fat diet [normal-fat diet (NF)], a 15% (wt:wt) fat diet [diet rich in saturated fat (HSF), saturated fatty acids accounted for 70% of total fatty acids], or HSF supplemented with 5% (wt:wt) wPB or 0.5% (wt:wt) hPB for 4 wk.
According to the plasma, liver, intestinal, and fecal samples that were collected to evaluate multiple cholesterol markers and gene targets,
* The plasma non-high-density lipoprotein (non-HDL) concentration was significantly reduced in the wPB- and hPB-supplemented groups by 31.9 ± 3.5% and 53.6 ± 3.2%, respectively, compared to the HSF group (P < 0.01), to concentrations comparable with the NF group
* The wPB-supplemented hamsters had significantly lower liver cholesterol (45.1%, P < 0.001) and higher fecal cholesterol concentrations (94.8%, P = 0.001) than those of the HSF group.
* The expressions of hepatic 3-hydroxy-3-methylglutaryl CoA reductase (Hmgcr) and small intestinal acyl-coenzyme A: cholesterol acyltransferase 2 (Acat2) associated with the elevation of blood cholesterol were significantly decreased in animals administered wPB (by 89.1% and 63.8%, respectively) and hPB (by 72.9% and 47.7%, respectively) compared to the HSF-fed counterparts (P < 0.05).
Based on the results, researchers suggest, "Pinto beans remediated high cholesterol induced by HSF in male hamsters by decreasing hepatic cholesterol synthesis and intestinal cholesterol absorption, effects which were partially exerted by the hulls".
Taken altogether, Pinto beans may be considered s functional for the treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pinto Beans (Phaseolus vulgaris L.) Lower Non-HDL Cholesterol in Hamsters Fed a Diet Rich in Saturated Fat and Act on Genes Involved in Cholesterol Homeostasis by Nguyen AT1,2, Althwab S3,4, Qiu H3, Zbasnik R1, Urrea C5, Carr TP3, Schlegel V. (PubMed)
#Cranberry Promotes #DigestiveFunction by Improving the Ratio of Gut Microbiota, According to Studies
Kyle J. Norton
Gut microbiota is a complex community with over a trillion microorganisms that live in our digestive tracts.
According to the ESMN, the microbiota can weigh up to 2 kg, including 1/3 of gut microbiota found in most people, compared to 2/3 that are specific to individuals depending on geography, environment, and lifestyle.
In healthy individuals, the ratio of good and bad microorganisms is balanced. In other words, healthy gut microbiota levels maintain the structure and function of the gastrointestinal tract.
A balanced ratio of gut microbiota plays a critical role in the digestion of certain foods that the stomach and small intestine have not been able to digest, in the production of vitamins, improvement of digestive functioning, and modulation of the immune function.
The use of antibiotics has been found to damage the gut ecosystem, leading to certain chronic illnesses such as inflammatory bowel disease, obesity, cancer, and autism.
Unhealthy gut microbiota has been found to
* Decrease the interaction with the immune function against inflammatory immune disorders.
* Increase the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
* Reduce nutrient extraction from the diet, thus increasing the risk of obesity and obesity complications.
* Increase the risk of controlling brain insulin signaling and metabolite levels that can lead to bad neurobehaviors.
Further, the unbalanced ratio of gut microbiota functions also alters immune homeostasis, leading to the onset of autoimmune disorders which in turn can affect the development of not only intestinal but also systemic autoimmune diseases.
Compared to probiotics, prebiotics is compound in food that induces the growth or activity of beneficial microorganisms in the gut.
In other definition, it is a special form of dietary fiber that acts as a fertilizer that promotes the growth of good bacteria in your gut.
In the gastrointestinal tract, prebiotics can alter the composition of organisms in the gut microbiome.
In other words, prebiotics raise the levels of healthy bacteria against bad bacteria.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound for the promotion of digestive functioning, researchers examined the effect of cranberries' impact on gut microbiota.
The randomized, double-blind, cross-over, controlled design trial included a total of 11 healthy adults consumed for 5 days each a control diet (animal-based diet (meats, dairy products, and simple sugars) plus 30 g/day placebo powder) and a cranberry diet (animal-based diet plus 30 g/day freeze-dried whole cranberry powder).
According to the tested analysis of the stool, urine, and blood samples, compared to the pre-control diet, the control diet modified 46 taxonomic clades in the gut, including an increase in the abundance of Firmicutes and a decrease in Bacteroidetes and increased bacteria-derived deoxycholic acid and decreased acetate and butyrate in stool
In other words, the control diet induces a significant change in gut microbiotas by favoring the "bad" organisms.
Compared to the post-control diet, the cranberry diet modified 9 taxonomic clades, including a decrease in the abundance of Firmicutes and an increase in Bacteroidetes in the flavor of the good organisms in the gut.
Furthermore, cranberry promoted the balancing ratio of gut microbiotas by attenuating control diet-induced increase in secondary bile acids decreasing the short-chain fatty acids (SCFA) and increasing urinary anthocyanins and bacterially derived phenolic acids.
Based on the findings, researchers said, "an animal-based diet altered the microbiota composition to a less favorable profile, increased carcinogenic bile acids, and decreased beneficial SCFA. Cranberries attenuated the impact of the animal-based diet on microbiota composition, bile acids, and SCFA, evidencing their capacity to modulate the gut microbiota".
Taken together, cranberry may be considered a remedy for the promotion of gut health, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries attenuate animal-based diet-induced changes in microbiota composition and functionality: a randomized crossover controlled feeding trial by Rodríguez-Morató J1, Matthan NR2, Liu J3, de la Torre R4, Chen CO. (PubMed)
(2) Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015 by Blumberg JB1, Basu A2, Krueger CG3, Lila MA4, Neto CC5, Novotny JA6, Reed JD3, Rodriguez-Mateos A7, Toner CD. (PubMed)
(3) The influence of antibiotics and dietary components on gut microbiota by Ruth K. Dudek-Wicher,
Adam Junka, and Marzenna Bartoszewicz. (PMC)
Gut microbiota is a complex community with over a trillion microorganisms that live in our digestive tracts.
According to the ESMN, the microbiota can weigh up to 2 kg, including 1/3 of gut microbiota found in most people, compared to 2/3 that are specific to individuals depending on geography, environment, and lifestyle.
In healthy individuals, the ratio of good and bad microorganisms is balanced. In other words, healthy gut microbiota levels maintain the structure and function of the gastrointestinal tract.
A balanced ratio of gut microbiota plays a critical role in the digestion of certain foods that the stomach and small intestine have not been able to digest, in the production of vitamins, improvement of digestive functioning, and modulation of the immune function.
The use of antibiotics has been found to damage the gut ecosystem, leading to certain chronic illnesses such as inflammatory bowel disease, obesity, cancer, and autism.
Unhealthy gut microbiota has been found to
* Decrease the interaction with the immune function against inflammatory immune disorders.
* Increase the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
* Reduce nutrient extraction from the diet, thus increasing the risk of obesity and obesity complications.
* Increase the risk of controlling brain insulin signaling and metabolite levels that can lead to bad neurobehaviors.
Further, the unbalanced ratio of gut microbiota functions also alters immune homeostasis, leading to the onset of autoimmune disorders which in turn can affect the development of not only intestinal but also systemic autoimmune diseases.
Compared to probiotics, prebiotics is compound in food that induces the growth or activity of beneficial microorganisms in the gut.
In other definition, it is a special form of dietary fiber that acts as a fertilizer that promotes the growth of good bacteria in your gut.
In the gastrointestinal tract, prebiotics can alter the composition of organisms in the gut microbiome.
In other words, prebiotics raise the levels of healthy bacteria against bad bacteria.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belonging to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound for the promotion of digestive functioning, researchers examined the effect of cranberries' impact on gut microbiota.
The randomized, double-blind, cross-over, controlled design trial included a total of 11 healthy adults consumed for 5 days each a control diet (animal-based diet (meats, dairy products, and simple sugars) plus 30 g/day placebo powder) and a cranberry diet (animal-based diet plus 30 g/day freeze-dried whole cranberry powder).
According to the tested analysis of the stool, urine, and blood samples, compared to the pre-control diet, the control diet modified 46 taxonomic clades in the gut, including an increase in the abundance of Firmicutes and a decrease in Bacteroidetes and increased bacteria-derived deoxycholic acid and decreased acetate and butyrate in stool
In other words, the control diet induces a significant change in gut microbiotas by favoring the "bad" organisms.
Compared to the post-control diet, the cranberry diet modified 9 taxonomic clades, including a decrease in the abundance of Firmicutes and an increase in Bacteroidetes in the flavor of the good organisms in the gut.
Furthermore, cranberry promoted the balancing ratio of gut microbiotas by attenuating control diet-induced increase in secondary bile acids decreasing the short-chain fatty acids (SCFA) and increasing urinary anthocyanins and bacterially derived phenolic acids.
Based on the findings, researchers said, "an animal-based diet altered the microbiota composition to a less favorable profile, increased carcinogenic bile acids, and decreased beneficial SCFA. Cranberries attenuated the impact of the animal-based diet on microbiota composition, bile acids, and SCFA, evidencing their capacity to modulate the gut microbiota".
Taken together, cranberry may be considered a remedy for the promotion of gut health, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries attenuate animal-based diet-induced changes in microbiota composition and functionality: a randomized crossover controlled feeding trial by Rodríguez-Morató J1, Matthan NR2, Liu J3, de la Torre R4, Chen CO. (PubMed)
(2) Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015 by Blumberg JB1, Basu A2, Krueger CG3, Lila MA4, Neto CC5, Novotny JA6, Reed JD3, Rodriguez-Mateos A7, Toner CD. (PubMed)
(3) The influence of antibiotics and dietary components on gut microbiota by Ruth K. Dudek-Wicher,
Adam Junka, and Marzenna Bartoszewicz. (PMC)
δ-#Tocopherol Supplemented Diet Inhibits the Risk and Onset of #ProstateCancer by Reduced Proliferation and Increased Apoptosis
Kyle J. Norton
The prostate gland wrapped around around a tube (the urethra), is a gland of the male reproductive system found in front of the rectum and just below the bladder. The prostate gland is a gland that makes and stores semen. It is located below the bladder and surrounds the tube that carries urine out of your body.
Additionally, the muscles of the prostate gland also play a critical role in propelling seminal fluid into the urethra during ejaculation
Symptoms of an enlarged prostate are associated with a natural impact on the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of an enlarged prostate.
Prostate cancer is a medical and chronic condition caused by the growth of cells irregularly in the tissue of the prostate.
Most cases of prostate cancer start in the cells on the surface of the inner lining of the prostate gland.
According to the statistics provided by the Canadian Cancer Society, prostate cancer is the third most common cancer among Canadian men and the 3rd leading cause of death from cancer in men in Canada.
In 2017, approximately 21,300 men were diagnosed with prostate cancer, accounting for 21% of all new cancer cases in men.
Furthermore, approximately 1 in 7 Canadian men will develop prostate cancer during their lifetime and 1 in 29 will die from it.
The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%.
In other words, For men diagnosed with prostate cancer that has not spread to other parts of the body, the 5-year survival rate is 100%.
However, the 5 years survival rate of prostate cancer that has spread to other parts of the body, is only 30%.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetables, and seed or nut oils, etc.
In finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocopherols on prostate cancer.
The study included specific Pten-/- (Ptenp-/-) mice induced cancer by activation of AKT cancer promotion signaling, fed by Ptenp-/- mice with AIN93M or 0.2% δ-T supplemented diet, at the age of 6 or 12 weeks. According to the analysis,
* δ-T treatment reduced prostate adenocarcinoma multiplicity at the age of 40 weeks by 53.3 and 42.7%, respectively.
* Furthermore, the phosphorylation of AKT (T308) that promotes cancer growth and survival was reduced in the prostate of the mice administered the δ-T diet.
* δ-T diet also, reduced proliferation and increased apoptosis in the prostate cancer cell line without affecting the oxidative stress.
Interestingly, α-tocopherol (α-T) at 0.2% in the diet exhibited anti-prostate cancer cell activity with no effects on prostate adenocarcinoma multiplicity in the Ptenp-/- mice.
After taking other factors into account, researchers said, " δ-T inhibits the development of prostate adenocarcinoma in Ptenp-/- mice, mainly through inhibition of AKT activation".
Taken together, tocopherols may be considered an adjunct therapy in the treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the prostate-specific international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoids, retinol, tocopherols, and prostate cancer risk: a pooled analysis of 15 studies by Key TJ1, Appleby PN2, Travis RC2, Albanes D3, Alberg AJ4, Barricarte A5, Black A3, Boeing H6, Bueno-de-Mesquita HB7, Chan JM8, Chen C9, Cook MB3, Donovan JL10, Galan P11, Gilbert R10, Giles GG12, Giovannucci E13, Goodman GE14, Goodman PJ15, Gunter MJ16, Hamdy FC17, Heliövaara M18, Helzlsouer KJ19, Henderson BE20, Hercberg S11, Hoffman-Bolton J21, Hoover RN3, Johansson M22, Khaw KT23, King IB24, Knekt P18, Kolonel LN25, Le Marchand L25, Männistö S18, Martin RM26, Meyer HE27, Mondul AM3, Moy KA3, Neal DE28, Neuhouser ML29, Palli D30, Platz EA31, Pouchieu C12, Rissanen H18, Schenk JM32, Severi G12, Stampfer MJ13, Tjønneland A33, Touvier M11, Trichopoulou A34, Weinstein SJ3, Ziegler RG3, Zhou CK3, Allen NE35; Endogenous Hormones Nutritional Biomarkers Prostate Cancer Collaborative Group. (PubMed)
(2) δ-Tocopherol inhibits the development of prostate adenocarcinoma in prostate specific Pten-/- mice by Wang H1, Yang X1, Liu A1, Wang G2, Bosland MC3, Yang CS. (PubMed)
The prostate gland wrapped around around a tube (the urethra), is a gland of the male reproductive system found in front of the rectum and just below the bladder. The prostate gland is a gland that makes and stores semen. It is located below the bladder and surrounds the tube that carries urine out of your body.
Additionally, the muscles of the prostate gland also play a critical role in propelling seminal fluid into the urethra during ejaculation
Symptoms of an enlarged prostate are associated with a natural impact on the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of an enlarged prostate.
Prostate cancer is a medical and chronic condition caused by the growth of cells irregularly in the tissue of the prostate.
Most cases of prostate cancer start in the cells on the surface of the inner lining of the prostate gland.
According to the statistics provided by the Canadian Cancer Society, prostate cancer is the third most common cancer among Canadian men and the 3rd leading cause of death from cancer in men in Canada.
In 2017, approximately 21,300 men were diagnosed with prostate cancer, accounting for 21% of all new cancer cases in men.
Furthermore, approximately 1 in 7 Canadian men will develop prostate cancer during their lifetime and 1 in 29 will die from it.
The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%.
In other words, For men diagnosed with prostate cancer that has not spread to other parts of the body, the 5-year survival rate is 100%.
However, the 5 years survival rate of prostate cancer that has spread to other parts of the body, is only 30%.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetables, and seed or nut oils, etc.
In finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocopherols on prostate cancer.
The study included specific Pten-/- (Ptenp-/-) mice induced cancer by activation of AKT cancer promotion signaling, fed by Ptenp-/- mice with AIN93M or 0.2% δ-T supplemented diet, at the age of 6 or 12 weeks. According to the analysis,
* δ-T treatment reduced prostate adenocarcinoma multiplicity at the age of 40 weeks by 53.3 and 42.7%, respectively.
* Furthermore, the phosphorylation of AKT (T308) that promotes cancer growth and survival was reduced in the prostate of the mice administered the δ-T diet.
* δ-T diet also, reduced proliferation and increased apoptosis in the prostate cancer cell line without affecting the oxidative stress.
Interestingly, α-tocopherol (α-T) at 0.2% in the diet exhibited anti-prostate cancer cell activity with no effects on prostate adenocarcinoma multiplicity in the Ptenp-/- mice.
After taking other factors into account, researchers said, " δ-T inhibits the development of prostate adenocarcinoma in Ptenp-/- mice, mainly through inhibition of AKT activation".
Taken together, tocopherols may be considered an adjunct therapy in the treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the prostate-specific international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoids, retinol, tocopherols, and prostate cancer risk: a pooled analysis of 15 studies by Key TJ1, Appleby PN2, Travis RC2, Albanes D3, Alberg AJ4, Barricarte A5, Black A3, Boeing H6, Bueno-de-Mesquita HB7, Chan JM8, Chen C9, Cook MB3, Donovan JL10, Galan P11, Gilbert R10, Giles GG12, Giovannucci E13, Goodman GE14, Goodman PJ15, Gunter MJ16, Hamdy FC17, Heliövaara M18, Helzlsouer KJ19, Henderson BE20, Hercberg S11, Hoffman-Bolton J21, Hoover RN3, Johansson M22, Khaw KT23, King IB24, Knekt P18, Kolonel LN25, Le Marchand L25, Männistö S18, Martin RM26, Meyer HE27, Mondul AM3, Moy KA3, Neal DE28, Neuhouser ML29, Palli D30, Platz EA31, Pouchieu C12, Rissanen H18, Schenk JM32, Severi G12, Stampfer MJ13, Tjønneland A33, Touvier M11, Trichopoulou A34, Weinstein SJ3, Ziegler RG3, Zhou CK3, Allen NE35; Endogenous Hormones Nutritional Biomarkers Prostate Cancer Collaborative Group. (PubMed)
(2) δ-Tocopherol inhibits the development of prostate adenocarcinoma in prostate specific Pten-/- mice by Wang H1, Yang X1, Liu A1, Wang G2, Bosland MC3, Yang CS. (PubMed)
#Fennel Biochemical Compounds Process A Strong Antioxidant Activity, Researchers Find
Kyle J. Norton
Imbalancing the ratio of the free radicals and antioxidants in the facilitation of oxidative stress was associated with the increased risk of the early onset of many chronic diseases, scientists found.
Fennel is a species of Foeniculum Vulgare, belonging to the family Apiaceae (Umbelliferae), and native to the shores of the Mediterranean, may process a potential effect in improving the levels of antioxidant enzymes produced by the human body, therefore, adding a portion of fennel on your daily diet should be helpful in reducing the risk of diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke ...
Dr. Moylan JS, the lead author in the study "Oxidative stress, chronic disease, and muscle wasting", wrote, "If an overproduction of oxidants overwhelms the antioxidant defenses, oxidative damage of cells, tissues, and organs ensue. In some cases, oxidative stress is assigned a causal role in disease pathogenesis, whereas in others the link is less certain".
Free radicals are unstable molecules with unpaired electrons produced daily in our body, reactive oxygen species, and reactive nitrogen can induce a domino's effect by stealing an electron from other molecules, leading to a continued function that cannot stop until they are paired or inhibited by the presence of antioxidant molecules.
If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, the process can cause oxidative damage accumulated during the life cycle, leading to the disruption in the function of the cells.
There are many risk factors that can increase the overexpression of free radicals, including fried foods, alcohol, tobacco smoke, pesticides, and air pollutants.
Therefore by changing your diet pattern with more fruits and vegetables, whole grains, and less red meat and processed foods and maintaining an active lifestyle, you can absolutely balance the ratio of free radicals and antioxidants in your body, thus decreasing the risk of many related chronic diseases.
In the review of the traditional use of fennel essential oils (EO) possess antimicrobial, anti-inflammable oil and insect repellent, anti-cancer, and antioxidant properties, researchers launched a comparison of essential oils and their main constituents in Citrus aurantium, C. limon, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare, and Thymus vulgaris.
EO of fennel showed the best free radicals scavenging capacity compared to others.
Fennel EO also was most effective against lipid peroxidation along with EO of C. limon.
Interestingly, after in-depth analysis, researchers discovered the antioxidant and anti-inflammatory activities of the EOs were plant-species-dependent and not always attributable to the EO's main components.
Additionally, in the evaluation of chemical constituents from essential oil from (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculum vulgare var. Vulgare, researchers suggested
* trans-Anethole, estragole, fenchone and limonene found highly abundant in all of the examined oils demonstrated strong antioxidant activities in the DPPH radical scavenging, lipid peroxidation, and metal chelating assays
* All 3 tested essentials display significant antimicrobial activities against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria.
Finally, in the study to assess the efficacy of medicinal plants used traditionally in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer, researchers found that fennel in comparison to other medical exerts a strong antioxidant effect through many of its bioactive compound such as phenolic compounds.
However, Dr. Škrovánková S, the lead scientist in the concerns of some conditions that may affect the herbal quality, said, "The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing.
Taken together, adding a portion of fennel into your diet may have a potential effect in increasing the levels of antioxidants in your body and countering the risk of overexpression of free radicals.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-oxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial essential oils by Aazza S, Lyoussi B, Megías C, Cortés-Giraldo I, Vioque J, Figueiredo AC, Miguel MG. (PubMed)
(4) Distillation time modifies essential oil yield, composition, and antioxidant capacity of fennel (Foeniculum vulgare Mill) by Zheljazkov VD1, Horgan T, Astatkie T, Schlegel V.(PubMed)
(3) Antioxidant activity and protecting health effects of common medicinal plants.
(4) Oxidative stress, chronic disease, and muscle wasting by Moylan JS1, Reid M. (PubMed)
Imbalancing the ratio of the free radicals and antioxidants in the facilitation of oxidative stress was associated with the increased risk of the early onset of many chronic diseases, scientists found.
Fennel is a species of Foeniculum Vulgare, belonging to the family Apiaceae (Umbelliferae), and native to the shores of the Mediterranean, may process a potential effect in improving the levels of antioxidant enzymes produced by the human body, therefore, adding a portion of fennel on your daily diet should be helpful in reducing the risk of diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke ...
Dr. Moylan JS, the lead author in the study "Oxidative stress, chronic disease, and muscle wasting", wrote, "If an overproduction of oxidants overwhelms the antioxidant defenses, oxidative damage of cells, tissues, and organs ensue. In some cases, oxidative stress is assigned a causal role in disease pathogenesis, whereas in others the link is less certain".
Free radicals are unstable molecules with unpaired electrons produced daily in our body, reactive oxygen species, and reactive nitrogen can induce a domino's effect by stealing an electron from other molecules, leading to a continued function that cannot stop until they are paired or inhibited by the presence of antioxidant molecules.
If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, the process can cause oxidative damage accumulated during the life cycle, leading to the disruption in the function of the cells.
There are many risk factors that can increase the overexpression of free radicals, including fried foods, alcohol, tobacco smoke, pesticides, and air pollutants.
Therefore by changing your diet pattern with more fruits and vegetables, whole grains, and less red meat and processed foods and maintaining an active lifestyle, you can absolutely balance the ratio of free radicals and antioxidants in your body, thus decreasing the risk of many related chronic diseases.
In the review of the traditional use of fennel essential oils (EO) possess antimicrobial, anti-inflammable oil and insect repellent, anti-cancer, and antioxidant properties, researchers launched a comparison of essential oils and their main constituents in Citrus aurantium, C. limon, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare, and Thymus vulgaris.
EO of fennel showed the best free radicals scavenging capacity compared to others.
Fennel EO also was most effective against lipid peroxidation along with EO of C. limon.
Interestingly, after in-depth analysis, researchers discovered the antioxidant and anti-inflammatory activities of the EOs were plant-species-dependent and not always attributable to the EO's main components.
Additionally, in the evaluation of chemical constituents from essential oil from (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculum vulgare var. Vulgare, researchers suggested
* trans-Anethole, estragole, fenchone and limonene found highly abundant in all of the examined oils demonstrated strong antioxidant activities in the DPPH radical scavenging, lipid peroxidation, and metal chelating assays
* All 3 tested essentials display significant antimicrobial activities against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria.
Finally, in the study to assess the efficacy of medicinal plants used traditionally in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer, researchers found that fennel in comparison to other medical exerts a strong antioxidant effect through many of its bioactive compound such as phenolic compounds.
However, Dr. Škrovánková S, the lead scientist in the concerns of some conditions that may affect the herbal quality, said, "The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing.
Taken together, adding a portion of fennel into your diet may have a potential effect in increasing the levels of antioxidants in your body and countering the risk of overexpression of free radicals.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-oxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial essential oils by Aazza S, Lyoussi B, Megías C, Cortés-Giraldo I, Vioque J, Figueiredo AC, Miguel MG. (PubMed)
(4) Distillation time modifies essential oil yield, composition, and antioxidant capacity of fennel (Foeniculum vulgare Mill) by Zheljazkov VD1, Horgan T, Astatkie T, Schlegel V.(PubMed)
(3) Antioxidant activity and protecting health effects of common medicinal plants.
(4) Oxidative stress, chronic disease, and muscle wasting by Moylan JS1, Reid M. (PubMed)
#Ginger and #ShellGinger Promotie Healthy Longevity by Exhibiting Anti-Inflammatory, Fungistatic, and Antibacterial Activities, According to Studies
Kyle J. Norton
Scientists may have a pungent spice that processes a potential for the promotion of healthy longevity, according to the study.
Compared to life expectancy which is the average number of years remaining of a given age or living of a certain group of people, longevity is a long life out of the boundary of the life expectancy.
Truly, we all dream of living healthy and with longevity. However how many of us can maintain health and prevent the onset of chronic disease?
Some researchers suggested that by following a healthy lifestyle and moderate exercise healthy longevity can be achieved.
Dr. Mehta N in the study of the healthy lifestyle impact on life expectancy wrote, "Compared to the whole US population, those with such a favorable behavioral profile had a life expectancy at age fifty that was seven years longer, and they experienced a delay in the onset of disability of up to six years".
The results clearly suggested the massively damaging effects caused by unhealthy behavioral risks on health at older ages.
Furthermore, Dr. Vincent Gremeaux and colleagues on the differentiation of exercise and longevity said, "As the number of older individuals continues to increase, it is important to develop interventions that can be easily implemented and contribute to “successful aging”".
And, " In addition to a healthy diet and psychosocial well-being, the benefits of regular exercise on mortality, and the prevention and control of chronic disease affecting both life expectancy and quality of life are well established".
Regularly moderate exercise has been found to have partially reverse effects on the aging process on physiological functions and preserve functional capability in the elderly.
Epidemiological studies strongly suggest that healthy longevity can be achieved by maintaining a minimum quantity and quality of exercise, preventing the development of certain cancers, and lowering the risk of osteoporosis.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a bioactive compound for healthy longevity examined the shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae) activity in the population in the Okinawa Islands of Japan.
According to the review of the literature, culinary shell ginger may contribute to longevity among the population in Okinawa probably due to the procession of phytochemical content with antioxidants and its effects on anti-obesity properties.
Some researchers suggested that the longevity of the population may also be attributed to the shell ginger in the promotion of health in reduced diseases by exhibiting anti-inflammatory, fungistatic, and antibacterial activities against Escherichia coli, Bacillus subtilis, and Bacillus cereus activity.
Shell ginger also is proven to have a positive effect on neuraminidase enzymes and inhibition of human immunodeficiency virus (HIV-1).
Dr. Rolf Teschke in the examination of the mortality rate of Japan's general public compared to the population on the island wrote, "Cardiovascular disease as the top cause of death for both sexes and neoplasms as the second leading cause of death in Japan nationally, with major variations among the prefectures"
And, " Comparing Japan overall with Okinawa, the mean mortality rates from ischaemic heart disease, Alzheimer’s disease, breast cancer, and oesophageal cancer were not remarkably different. However, for Okinawa, four death categories were significantly lower, including ischaemic stroke, stomach cancer, pancreatic cancer, and liver cancer due to hepatitis C.
The finding clearly suggested that the intake of shell ginger which was not found in other areas in Japan may contribute to the healthy longevity of the population in the Okinawa Islands of Japan.
In a joint study led by Woosuk University, Korean scientists evaluated the compound 6-gingerol longevity-promoting activity. isolated from the most active ethyl acetate soluble fraction on Caenorhabditis elegans (C. elegans).
Injection of 6 gingerol elevated the survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The bioactive compound elevated the antioxidant enzyme activities of C. elegans and showed a dose-dependent reduction of intracellular reactive oxygen species (ROS) accumulation in worms.
Furthermore, 6 gingerols also demonstrated increased stress tolerance, leading to the promotion of stress resistance proteins.
The findings strongly suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.
Taken together, ginger and shell ginger may be considered functional foods for the promotion of healthy longevity with no side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 and Dae Keun Kim. (PubMed)
(2) Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet) for Human Longevity in Okinawa, Japan? by Rolf Teschke1,* and Tran Dang Xuan. (PMC)
(3) The Population Health Benefits Of A Healthy Lifestyle: Life Expectancy Increased And Onset Of Disability Delayed by Mehta N1, Myrskylä M. (PubMed)
(4) Exercise and longevity by Vincent Gremeaux, Duxabcdef, MathieuGay, RomualdLeperse, Philippe Sosneraghi, MartinJuneau, AnilNigam. (Science Direct)
Scientists may have a pungent spice that processes a potential for the promotion of healthy longevity, according to the study.
Compared to life expectancy which is the average number of years remaining of a given age or living of a certain group of people, longevity is a long life out of the boundary of the life expectancy.
Truly, we all dream of living healthy and with longevity. However how many of us can maintain health and prevent the onset of chronic disease?
Some researchers suggested that by following a healthy lifestyle and moderate exercise healthy longevity can be achieved.
Dr. Mehta N in the study of the healthy lifestyle impact on life expectancy wrote, "Compared to the whole US population, those with such a favorable behavioral profile had a life expectancy at age fifty that was seven years longer, and they experienced a delay in the onset of disability of up to six years".
The results clearly suggested the massively damaging effects caused by unhealthy behavioral risks on health at older ages.
Furthermore, Dr. Vincent Gremeaux and colleagues on the differentiation of exercise and longevity said, "As the number of older individuals continues to increase, it is important to develop interventions that can be easily implemented and contribute to “successful aging”".
And, " In addition to a healthy diet and psychosocial well-being, the benefits of regular exercise on mortality, and the prevention and control of chronic disease affecting both life expectancy and quality of life are well established".
Regularly moderate exercise has been found to have partially reverse effects on the aging process on physiological functions and preserve functional capability in the elderly.
Epidemiological studies strongly suggest that healthy longevity can be achieved by maintaining a minimum quantity and quality of exercise, preventing the development of certain cancers, and lowering the risk of osteoporosis.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a bioactive compound for healthy longevity examined the shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae) activity in the population in the Okinawa Islands of Japan.
According to the review of the literature, culinary shell ginger may contribute to longevity among the population in Okinawa probably due to the procession of phytochemical content with antioxidants and its effects on anti-obesity properties.
Some researchers suggested that the longevity of the population may also be attributed to the shell ginger in the promotion of health in reduced diseases by exhibiting anti-inflammatory, fungistatic, and antibacterial activities against Escherichia coli, Bacillus subtilis, and Bacillus cereus activity.
Shell ginger also is proven to have a positive effect on neuraminidase enzymes and inhibition of human immunodeficiency virus (HIV-1).
Dr. Rolf Teschke in the examination of the mortality rate of Japan's general public compared to the population on the island wrote, "Cardiovascular disease as the top cause of death for both sexes and neoplasms as the second leading cause of death in Japan nationally, with major variations among the prefectures"
And, " Comparing Japan overall with Okinawa, the mean mortality rates from ischaemic heart disease, Alzheimer’s disease, breast cancer, and oesophageal cancer were not remarkably different. However, for Okinawa, four death categories were significantly lower, including ischaemic stroke, stomach cancer, pancreatic cancer, and liver cancer due to hepatitis C.
The finding clearly suggested that the intake of shell ginger which was not found in other areas in Japan may contribute to the healthy longevity of the population in the Okinawa Islands of Japan.
In a joint study led by Woosuk University, Korean scientists evaluated the compound 6-gingerol longevity-promoting activity. isolated from the most active ethyl acetate soluble fraction on Caenorhabditis elegans (C. elegans).
Injection of 6 gingerol elevated the survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The bioactive compound elevated the antioxidant enzyme activities of C. elegans and showed a dose-dependent reduction of intracellular reactive oxygen species (ROS) accumulation in worms.
Furthermore, 6 gingerols also demonstrated increased stress tolerance, leading to the promotion of stress resistance proteins.
The findings strongly suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.
Taken together, ginger and shell ginger may be considered functional foods for the promotion of healthy longevity with no side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 and Dae Keun Kim. (PubMed)
(2) Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet) for Human Longevity in Okinawa, Japan? by Rolf Teschke1,* and Tran Dang Xuan. (PMC)
(3) The Population Health Benefits Of A Healthy Lifestyle: Life Expectancy Increased And Onset Of Disability Delayed by Mehta N1, Myrskylä M. (PubMed)
(4) Exercise and longevity by Vincent Gremeaux, Duxabcdef, MathieuGay, RomualdLeperse, Philippe Sosneraghi, MartinJuneau, AnilNigam. (Science Direct)
#Fennel Essential Oil and Extract Process a Strong #Hypoglycemic Activity, Scientists Reveal
Kyle J. Norton
Fennel may have a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found. In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.
Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.
Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick, or high levels of stress in patients with diabetes also can cause blood glucose uptake.
Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.
Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections
Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean
The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and anti-depression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the examination of the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.
At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.
The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.
After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.
Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.
However, the injection of fennel extract exhibited the highest toxicity.
These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.
Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that
* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.
* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.
* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.
This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.
Taken together, fennel extract and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)
Fennel may have a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found. In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.
Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.
Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick, or high levels of stress in patients with diabetes also can cause blood glucose uptake.
Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.
Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections
Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean
The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and anti-depression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the examination of the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.
At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.
The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.
After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.
Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.
However, the injection of fennel extract exhibited the highest toxicity.
These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.
Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that
* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.
* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.
* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.
This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.
Taken together, fennel extract and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)
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