Kyle J. Norton
Hyperglycemia is a medical condition characterized by abnormally high levels of glucose in the bloodstream
Although hyperglycemia is a hallmark in patients with diabetes, the condition can also occur in people without diabetes due to a certain medical condition such as pneumonia in the elderly.
Dr. Yuan Lin, the lead scientists in the examination of hyperglycemia in patients with an
acute pancreatitis (AP) wrote, "Hyperlipidemia, fatty liver, hypertension, endoscopic retrograde cholangiopancreatography treatment, acute hyperglycemia, elevated lactate dehydrogenase, and creatine kinase, decreased calcium, and AB blood type were risk factors for hyperglycemia development after AP".
The most common causes of hyperglycemia are associated with an uncontrolled diet, improper use of insulin, and skipping diabetic medication.
The most common symptoms of hyperglycemia are increased thirst frequent urination, fatigue (weak, and unintended weight loss. In severe cases, some patients may also experience symptoms of headaches, trouble concentrating, and blurred vision.
If you have experienced some of the aforementioned symptoms, you may have abnormally elevated high blood sugar.
Untreated hyperglycemia can lead to serious complications requiring emergency care, such as a diabetic coma. Over the long term, persistently mild hyperglycemia can lead to complications in the eyes, kidneys, nerve damage and heart disease, and stroke.
By following the guidelines and recommendations in the management of blood glucose accompanied by healthy and moderate exercise, diabetics may do just fine against hyperglycemia.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
In finding a potential compound for the treatment of hyperglycemia, researchers examined the effect of alliin against metabolic risk factors in diet-induced obese (DIO) mice.
Selected C57BL/6J DIO diet-induced obese mice are treated with drinking water with or without alliin (0.1 mg/ml) for 8 weeks.
Oral administration of alliin enhanced glucose homeostasis, increased insulin sensitivity, and improved the lipid profile in the DIO mic without affecting the body weight, adiposity, or energy balance.
In other words, alliin inhibited hyperglycemia selectively without normalizing the adiposity tissues' inappropriate responses of energy intake and energy expenditure.
Based on the tested results, researchers found that the efficacy of alliin in the inhibition of hyperglycemia is partly associated with the modulation of the intestinal microbiota composition, typically decreased Lachnospiraceae and increased Ruminococcaceae.
In order to reveal more information about alliin antihyperglycemic activity, researchers examined the production and therapeutic efficiency of alliin extracted from garlic leaves of plants grown under ex-situ and in-situ conditions.
According to the results of alliin aqueous leaf extracts (from ex-situ and in situ grown plants) were given to normal and alloxan-induced diabetic rats for five weeks, under in situ conditions, alliin extract lowered the serum glucose, triglycerides, total lipids, and total cholesterol, low-density lipoprotein (LDL)-, and very-low-density lipoprotein (VLDL)-cholesterol in diabetic rats by ~54%, 15%, 14%, 20%, 24%, and 15% compared to 35%, 14%, 10%, 12%, 17% and 11% from the ex-situ grown plants.
Furthermore, compared to glibenclamide, the leaf extract of plants lowered serum enzyme levels (alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase) associated with liver oxidative stress toward the normal.
Moreover, The histopathological alteration in the pancreas caused by alloxan was also inhibited markedly by leaf extract.
Based on the findings, Dr. Nasim SA, the lead scientist wrote, "These findings demonstrate leaf extract obtained from plants grown under in situ conditions possess higher therapeutic efficiency in comparison with leaf extract obtained from plants grown under ex-situ condition".
In other words, geographic growth may influence the therapeutic potential of phytochemicals in plants.
Taken together, alliin may be considered a supplement for the prevention and treatment of hyperglycemia, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice by Zhai B1, Zhang C1, Sheng Y1, Zhao C2, He X1,3, Xu W1,3, Huang K1,3, Luo Y. (PubMed)
(2) Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats by Nasim SA1, Dhir B, Kapoor R, Fatima S, Mahmooduzzafar, Mujib A. (PubMed)
(3) Risk Factors of Hyperglycemia in Patients After a First Episode of Acute Pancreatitis: A Retrospective Cohort by Yuan L1, Tang M, Huang L, Gao Y, Li X. (PubMed)
Saturday, 19 August 2023
#Broccoli or #BroccoliSprouts Show no Effects on #Thyroid-Stimulating Hormone, Free Thyroxine, and Thyroglobulin, According to Studies
Kyle J. Norton
Thyroid disease is a medical condition that causes a malfunction of the thyroid.
Hyperthyroidism is a condition in which the thyroid gland is overactive and produces too much thyroid hormones.
The most common symptoms of hyperthyroidism are excessive sweating, heat intolerance, increased bowel movements, shaking, nervousness, agitation, anxiety, rapid heart rate, palpitations, irregular heart rate, weight loss, fatigue, weakness...
Hypothyroidism is a condition in which the thyroid gland is underactive and produces very little thyroid hormones.
Symptoms of hypothyroidism are depended on the severe stage of the disease. as it progresses slowly over years such as weight gain and fatigue, vitiligo and alopecia areata, chronic constipation, urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin, alopecia periorbital edema, amenorrhea, dyspareunia, PCO, PMS and breast tenderness, menstrual irregularities and infertility,...
Thyroid toxicity that affects the function of the thyroid gland not only causes thyroid dysfunction but also induce thyroid autoimmune disease.
According to Dr. Catherine Sutcliffe, the lead scientist in the study of "Endocrine Disruption of Thyroid Function" wrote, "The common factor in the direct thyroid toxicity mechanisms so far outlined is the reduction of thyroid hormone production and secretion. The reduction of thyroid hormones (T4 or T3) results in compensatory increased secretion of TSH due to the concomitant diminution of feedback control (see Figure 11.3)".
And, "It is important to note that increased TSH stimulation of the thyroid produces the same histopathological effects irrespective of the mechanism by which TSH is increased including thyroid growth evidenced by increased size and weight".
There are a number of causes of thyroid toxicity including short and long term intake of some medications (sunitinib has been found to cause thrombocytopenia and hypoglycemia in 62 patients) and xenobiotics.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding thyroidal toxicity of sulforaphane, a redox-active natural product present in cruciferous vegetables like broccoli. Broccoli sprout, researchers examined the effect of the phytochemical sulforaphane effect on Nrf2 (NFE2-related factor 2) that leads to thyroid dysfunction or thyroid autoimmune disease.
According to the results of the biochemical measures of thyroid function and thyroid autoimmunity in 45 female participants in a randomized clinical trial at baseline and after 84 days of beverage administration, researchers found that
* Broccoli sprout-derived products shows promising activity for the prevention of oxidative stress-related diseases.
* Sulforaphane did not affect the serum levels of thyroid-stimulating hormone, free thyroxine, and thyroglobulin.
* More importantly, sulforaphane does not affect thyroid autoimmunity status.
Based on the findings, researchers said, "These results provide evidence in favor of the safety of chemoprevention strategies that target the activation of Nrf2 to protect against environmental exposures and other oxidative stress-related pathologies".
Taken altogether, Broccoli sprouts may is safe for the prevention and treatment of oxidative stress-related diseases without causing thyroidal toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial by Chartoumpekis DV1, Ziros PG2, Chen JG3, Groopman JD4, Kensler TW1, Sykiotis GP. (PubMed)
(2) Thyroid Toxicity (Science Direct)
Thyroid disease is a medical condition that causes a malfunction of the thyroid.
Hyperthyroidism is a condition in which the thyroid gland is overactive and produces too much thyroid hormones.
The most common symptoms of hyperthyroidism are excessive sweating, heat intolerance, increased bowel movements, shaking, nervousness, agitation, anxiety, rapid heart rate, palpitations, irregular heart rate, weight loss, fatigue, weakness...
Hypothyroidism is a condition in which the thyroid gland is underactive and produces very little thyroid hormones.
Symptoms of hypothyroidism are depended on the severe stage of the disease. as it progresses slowly over years such as weight gain and fatigue, vitiligo and alopecia areata, chronic constipation, urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin, alopecia periorbital edema, amenorrhea, dyspareunia, PCO, PMS and breast tenderness, menstrual irregularities and infertility,...
Thyroid toxicity that affects the function of the thyroid gland not only causes thyroid dysfunction but also induce thyroid autoimmune disease.
According to Dr. Catherine Sutcliffe, the lead scientist in the study of "Endocrine Disruption of Thyroid Function" wrote, "The common factor in the direct thyroid toxicity mechanisms so far outlined is the reduction of thyroid hormone production and secretion. The reduction of thyroid hormones (T4 or T3) results in compensatory increased secretion of TSH due to the concomitant diminution of feedback control (see Figure 11.3)".
And, "It is important to note that increased TSH stimulation of the thyroid produces the same histopathological effects irrespective of the mechanism by which TSH is increased including thyroid growth evidenced by increased size and weight".
There are a number of causes of thyroid toxicity including short and long term intake of some medications (sunitinib has been found to cause thrombocytopenia and hypoglycemia in 62 patients) and xenobiotics.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding thyroidal toxicity of sulforaphane, a redox-active natural product present in cruciferous vegetables like broccoli. Broccoli sprout, researchers examined the effect of the phytochemical sulforaphane effect on Nrf2 (NFE2-related factor 2) that leads to thyroid dysfunction or thyroid autoimmune disease.
According to the results of the biochemical measures of thyroid function and thyroid autoimmunity in 45 female participants in a randomized clinical trial at baseline and after 84 days of beverage administration, researchers found that
* Broccoli sprout-derived products shows promising activity for the prevention of oxidative stress-related diseases.
* Sulforaphane did not affect the serum levels of thyroid-stimulating hormone, free thyroxine, and thyroglobulin.
* More importantly, sulforaphane does not affect thyroid autoimmunity status.
Based on the findings, researchers said, "These results provide evidence in favor of the safety of chemoprevention strategies that target the activation of Nrf2 to protect against environmental exposures and other oxidative stress-related pathologies".
Taken altogether, Broccoli sprouts may is safe for the prevention and treatment of oxidative stress-related diseases without causing thyroidal toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial by Chartoumpekis DV1, Ziros PG2, Chen JG3, Groopman JD4, Kensler TW1, Sykiotis GP. (PubMed)
(2) Thyroid Toxicity (Science Direct)
#Asparagus Root #Extract Processes Anti Inflammatory Activity through Regualting the Immune Response, Researchers Suggest
Kyle J. Norton
Asparagus is a flowering plant belonging to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.
Asparagus may be the next potential whole food medicine in the inhibited expression of pro-inflammatory cytokines in inducing fever, pain, and swelling in the affected location,...
Inflammation is a natural expression by the immune system in the induction of white blood cells for the protection of our body against infection with foreign invasion.
According to the Korea Institute of Oriental Medicine, in an investigation of chronic skin inflammation, using 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema, administration at 200mg/kg (i.p.) of ethanolic extract from Asparagus cochinchinensis Merrill (ACE)expressed strong anti-inflammatory effect through inhibited topical edema in the mouse ear, and substantial reductions in skin thickness and tissue weight, inflammatory cytokine production,.....
Dr. Lee DY, the lead author in the study said, "ACE is an effective anti-inflammatory agent in murine phorbol ester-induced dermatitis" and " the compound may have therapeutic potential in a variety of immune-related cutaneous diseases."
The study of pharmacological properties of Asparagus racemosus root extracts (AR), also addressed the potential use of extract formulation for topical and/or transdermal drugs to provide anti-inflammatory activity, due to its significant attenuation involved in systemic inflammation, without causing toxicity to experiment monocytic leukemia cell line THP-1.
Furthermore, the extract from asparagus also exerts an inhibitory effect on pro-inflammatory cytokines, namely interleukin 1β and tumor necrosis factor α, and on the production of nitric oxide in free radical-mediated lipid oxidation stimulated by lipopolysaccharide in regulated immune response in vitro.
Some researchers insisted the properties of anti-inflammation of asparagus may also be due to the presence of phytochemical saponin contents in comparison to the group treated with crude saponin extracts in the rat paw-edema and the control group.
Taken together, Asparagus may have a potential anti-inflammatory effect in reduced risk and treatment of chronic inflammatory diseases. The efficacy is not due to a single ingredient in the food but the whole food.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation by Lee DY1, Choo BK, Yoon T, Cheon MS, Lee HW, Lee AY, Kim HK.(PubMed)
(2) Anti-inflammatory activity of liposomes of Asparagus racemosus root extracts prepared by various methods by Plangsombat N1, Rungsardthong K2, Kongkaneramit L3, Waranuch N4, Sarisuta N5.(PubMed)
(3) Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagusracemosus on pro-inflammatory cytokine and corticosterone levels produced by stress by Kanwar AS1, Bhutani KK.(PubMed)
(4) Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants by Hassan HS1, Sule MI, Musa AM, Musa KY, Abubakar MS, Hassan AS.(PubMed)
Asparagus is a flowering plant belonging to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.
Asparagus may be the next potential whole food medicine in the inhibited expression of pro-inflammatory cytokines in inducing fever, pain, and swelling in the affected location,...
Inflammation is a natural expression by the immune system in the induction of white blood cells for the protection of our body against infection with foreign invasion.
According to the Korea Institute of Oriental Medicine, in an investigation of chronic skin inflammation, using 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema, administration at 200mg/kg (i.p.) of ethanolic extract from Asparagus cochinchinensis Merrill (ACE)expressed strong anti-inflammatory effect through inhibited topical edema in the mouse ear, and substantial reductions in skin thickness and tissue weight, inflammatory cytokine production,.....
Dr. Lee DY, the lead author in the study said, "ACE is an effective anti-inflammatory agent in murine phorbol ester-induced dermatitis" and " the compound may have therapeutic potential in a variety of immune-related cutaneous diseases."
The study of pharmacological properties of Asparagus racemosus root extracts (AR), also addressed the potential use of extract formulation for topical and/or transdermal drugs to provide anti-inflammatory activity, due to its significant attenuation involved in systemic inflammation, without causing toxicity to experiment monocytic leukemia cell line THP-1.
Furthermore, the extract from asparagus also exerts an inhibitory effect on pro-inflammatory cytokines, namely interleukin 1β and tumor necrosis factor α, and on the production of nitric oxide in free radical-mediated lipid oxidation stimulated by lipopolysaccharide in regulated immune response in vitro.
Some researchers insisted the properties of anti-inflammation of asparagus may also be due to the presence of phytochemical saponin contents in comparison to the group treated with crude saponin extracts in the rat paw-edema and the control group.
Taken together, Asparagus may have a potential anti-inflammatory effect in reduced risk and treatment of chronic inflammatory diseases. The efficacy is not due to a single ingredient in the food but the whole food.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation by Lee DY1, Choo BK, Yoon T, Cheon MS, Lee HW, Lee AY, Kim HK.(PubMed)
(2) Anti-inflammatory activity of liposomes of Asparagus racemosus root extracts prepared by various methods by Plangsombat N1, Rungsardthong K2, Kongkaneramit L3, Waranuch N4, Sarisuta N5.(PubMed)
(3) Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagusracemosus on pro-inflammatory cytokine and corticosterone levels produced by stress by Kanwar AS1, Bhutani KK.(PubMed)
(4) Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants by Hassan HS1, Sule MI, Musa AM, Musa KY, Abubakar MS, Hassan AS.(PubMed)
#Healthyfood #Cranberry Processes Anticancer Activity, According to Studies
Kyle J. Norton
Cancers are a class of chronic and medical conditions characterized by cells growth irregularly and disorderly in the tissue of a specific organ.
Most cases of cancer start in the cell on the surface of the inner lining of organ tissue caused by the alternation of the cell DNA.
At the early stage, due to the very small size of the tumor, patients may not experience any symptoms. However, as the cancer progression, cancer cells may penetrate into deeper layers, before colonizing entire organs. At this stage, the primary cancer cells can travel a distance away from the original site to infect other healthy tissue and organ via fluid and blood circulation.
According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes, based on the 2013–2015 data.
In 2017, about15,270 children and adolescents ages 0 to 19 were diagnosed with cancer. Cancer in the same year also causes the death 1,790 of children and adolescents Americans.
As of today, researchers do not know the exact cause of cancer neither they know why people with the same health condition and family history, some are susceptible to DNA alternation in facilitating the onset of cancer, while others do not.
There are many prevalent factors associated with cancer onset, including an increase of age, excessive alcohol consumption, exposure to chemical toxins and sunlight, and infectious pathogens.
Most common factors that cause the rise of cancer, including colorectal cancer in the Western world according to Dr. Omran S, the led author in the study of "Dietary and Lifestyle Risk Factors for Colorectal Cancer in Apparently Healthy Adults in Jordanian Hospitals" are dietary patterns, sedentary lifestyle, and other practices.
In CRC risk, the doctor continued, aging with the mean age of 57.0 ± 8.56 years, male gender with less than secondary school formal education.
And, the commonest risk factors for CRC among the participants were overweight or obesity (76.1 %), lack of exercise (71.6 %), limited consumption of vegetables (70.8 %), smoking (60.6 %), over-consumption of red meat (56.3 %), and diabetes mellitus (24.1 %)".
However, most people with some of the aforementioned risk factors have never developed cancer.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound that processes chemopreventive activity, researchers assessed the anti-cancer activities of Chlorhexidine (CHX) and Cranberry against oral cancer cell lines.
According to the results of AW13516 (poorly to moderately differentiated squamous cell carcinoma of the tongue) and KB (Nasopharyngeal carcinoma) using Sulforhodamine B (SRB) assays, the CHX efficacy of 80.15% & 95.7% of growth inhibition against AW13516 & KB cell line respectively.
* Administration of CE (80µg/ml) showed no anti-cancer properties against the AW13516 cell line.
*However, CE inhibited 70.6% growth against the KB cell line.
Furthermore, both CHX and CE were less potential than the positive control drug Adriamycin, at the values of GI50, TGI, and LC50.
Based on the findings, researchers said, "CHX exhibited better anti-cancer properties than CE for both the oral cancer cell lines".
In other words, CE exerted anti-cancer activity depending on the types of primary cancer cells.
Taken together, cranberry may be considered a remedy for the prevention and treatment of cancer, depending on the types of primary cancer cells, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anticancer activity of chlorhexidine and cranberry extract: an in-vitro study by Khairnar MR1, Wadgave U1, Jadhav H2, Naik R. (PubMed)
(2) Cranberry and its phytochemicals: a review of in vitro anticancer studies by Neto CC. (PubMed)
Cancers are a class of chronic and medical conditions characterized by cells growth irregularly and disorderly in the tissue of a specific organ.
Most cases of cancer start in the cell on the surface of the inner lining of organ tissue caused by the alternation of the cell DNA.
At the early stage, due to the very small size of the tumor, patients may not experience any symptoms. However, as the cancer progression, cancer cells may penetrate into deeper layers, before colonizing entire organs. At this stage, the primary cancer cells can travel a distance away from the original site to infect other healthy tissue and organ via fluid and blood circulation.
According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes, based on the 2013–2015 data.
In 2017, about15,270 children and adolescents ages 0 to 19 were diagnosed with cancer. Cancer in the same year also causes the death 1,790 of children and adolescents Americans.
As of today, researchers do not know the exact cause of cancer neither they know why people with the same health condition and family history, some are susceptible to DNA alternation in facilitating the onset of cancer, while others do not.
There are many prevalent factors associated with cancer onset, including an increase of age, excessive alcohol consumption, exposure to chemical toxins and sunlight, and infectious pathogens.
Most common factors that cause the rise of cancer, including colorectal cancer in the Western world according to Dr. Omran S, the led author in the study of "Dietary and Lifestyle Risk Factors for Colorectal Cancer in Apparently Healthy Adults in Jordanian Hospitals" are dietary patterns, sedentary lifestyle, and other practices.
In CRC risk, the doctor continued, aging with the mean age of 57.0 ± 8.56 years, male gender with less than secondary school formal education.
And, the commonest risk factors for CRC among the participants were overweight or obesity (76.1 %), lack of exercise (71.6 %), limited consumption of vegetables (70.8 %), smoking (60.6 %), over-consumption of red meat (56.3 %), and diabetes mellitus (24.1 %)".
However, most people with some of the aforementioned risk factors have never developed cancer.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound that processes chemopreventive activity, researchers assessed the anti-cancer activities of Chlorhexidine (CHX) and Cranberry against oral cancer cell lines.
According to the results of AW13516 (poorly to moderately differentiated squamous cell carcinoma of the tongue) and KB (Nasopharyngeal carcinoma) using Sulforhodamine B (SRB) assays, the CHX efficacy of 80.15% & 95.7% of growth inhibition against AW13516 & KB cell line respectively.
* Administration of CE (80µg/ml) showed no anti-cancer properties against the AW13516 cell line.
*However, CE inhibited 70.6% growth against the KB cell line.
Furthermore, both CHX and CE were less potential than the positive control drug Adriamycin, at the values of GI50, TGI, and LC50.
Based on the findings, researchers said, "CHX exhibited better anti-cancer properties than CE for both the oral cancer cell lines".
In other words, CE exerted anti-cancer activity depending on the types of primary cancer cells.
Taken together, cranberry may be considered a remedy for the prevention and treatment of cancer, depending on the types of primary cancer cells, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anticancer activity of chlorhexidine and cranberry extract: an in-vitro study by Khairnar MR1, Wadgave U1, Jadhav H2, Naik R. (PubMed)
(2) Cranberry and its phytochemicals: a review of in vitro anticancer studies by Neto CC. (PubMed)
#Antioxidant #Lycopene Inhibits #SkinCancer Associated with Enhancing the Expression of the Tight Junction Complexes, Researchers Say
Kyle J. Norton
Skin cancer is a medical condition associated with irregular cell growth in the skin tissues.
Most cases of skin cancer start in the cells on the surface of the outermost inner lining tissue before penetrating into deeper layers.
After growing in size at the advanced stage, the cells of the tumor may travel a distance away to infect other healthy tissue and organs through blood and fluid circulation.
The most common secondary metastasis of skin cancer is breast, lung, and colon.
Believe it or not, more people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. As of today, there are 58 million Americans living with skin cancer.
Approximately, 1 in 5 Americans will develop skin cancer by the age of 70.
If you have experienced some of the symptoms such as a sore that doesn't heal or comes back after healing, pale white or yellow flat areas that look like scars, raised and scaly red patches, small, smooth, and shiny lumps that are pearly white, pink or red, a pink growth with raised edges and indents in the center and a growth that has small blood vessels on the surface of the skin, you may be on the early stage of skin cancer, please check with your doctor immediately.
The 5-year survival of all people with melanoma of the skin is 92% compared to 100% of those localized skin cancer.
Out of many prevalent factors that cause skin cancer, some researchers suggested exposure to UVB is one of most risk associated with skin cancer onset in the US.
Dr. Calzavara-Pinton P, the lead scientist said, "BCC is much more strongly related to measures of intermittent ultraviolet exposure (particularly those of childhood or adolescence) than to measures of cumulative exposure".
And, " In contrast, SCC is more strongly related to constant or cumulative sun exposure. Photobiological studies have clarified that sunlight and UVB radiation are complete carcinogens for AK and SCC although the relationship with UVA exposure is much less known".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In the urgency to find a natural compound for the treatment of skin cancer without side effects, researchers evaluated the effect of lycopene, a kind of carotenoid inhibitory function on skin tumor cell migration.
In the human sSCC cell line COLO-16 selected for the study, the administration of lycopene inhibited the cell proliferation and migration of COLO-16 cells without affecting the normal keratinocytes.
Furthermore, the inhibitory activity was found by exhibiting Zonula occludens (ZO)-1, inhibition of ZO-1 expression, and its failure to accumulate at cell junctions (ZO-1 and claudin-1) have been found to induce cancer progression.
In other words, lycopene inhibited the SCC cell line COLO-16 proliferation by enhancing the expression of the tight junction complexes that regulate the permeability of epithelial against cancer cells.
Additionally, cell cycle division proteins (JNK and ERK ) in the induction of mitogen associated with the decreasing levels of ZO-1 and claudin-1 were also inhibited by the injection of lycopene.
More precisely, lycopene inhibited the progression of human sSCC cell line COLO-16 by reducing the proteins involved in promoting cell cycle division and increasing cancer cell permeability and autophagy,
Based on the findings researchers said, "This study indicates that lycopene might be a useful chemopreventive agent against cSCC".
Taken together, lycopene may be considered supplements for the prevention and treatment of skin cancer, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene upregulates ZO-1 and downregulates claudin-1 through autophagy inhibition in the human cutaneous squamous cell carcinoma cell line COLO-16 by Bi S1,2, Li L1, Gu H1, Li M1, Xu S1, Bu W1, Zhang M1, Zhou Z2, Chen X. (PubMed)
(2) Suppressive effects of lycopene and β-carotene on the viability of the human esophageal squamous carcinoma cell line EC109 by Ngoc NB1,2, Lv P1,3, Zhao WE1. (PubMed)
Skin cancer is a medical condition associated with irregular cell growth in the skin tissues.
Most cases of skin cancer start in the cells on the surface of the outermost inner lining tissue before penetrating into deeper layers.
After growing in size at the advanced stage, the cells of the tumor may travel a distance away to infect other healthy tissue and organs through blood and fluid circulation.
The most common secondary metastasis of skin cancer is breast, lung, and colon.
Believe it or not, more people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. As of today, there are 58 million Americans living with skin cancer.
Approximately, 1 in 5 Americans will develop skin cancer by the age of 70.
If you have experienced some of the symptoms such as a sore that doesn't heal or comes back after healing, pale white or yellow flat areas that look like scars, raised and scaly red patches, small, smooth, and shiny lumps that are pearly white, pink or red, a pink growth with raised edges and indents in the center and a growth that has small blood vessels on the surface of the skin, you may be on the early stage of skin cancer, please check with your doctor immediately.
The 5-year survival of all people with melanoma of the skin is 92% compared to 100% of those localized skin cancer.
Out of many prevalent factors that cause skin cancer, some researchers suggested exposure to UVB is one of most risk associated with skin cancer onset in the US.
Dr. Calzavara-Pinton P, the lead scientist said, "BCC is much more strongly related to measures of intermittent ultraviolet exposure (particularly those of childhood or adolescence) than to measures of cumulative exposure".
And, " In contrast, SCC is more strongly related to constant or cumulative sun exposure. Photobiological studies have clarified that sunlight and UVB radiation are complete carcinogens for AK and SCC although the relationship with UVA exposure is much less known".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In the urgency to find a natural compound for the treatment of skin cancer without side effects, researchers evaluated the effect of lycopene, a kind of carotenoid inhibitory function on skin tumor cell migration.
In the human sSCC cell line COLO-16 selected for the study, the administration of lycopene inhibited the cell proliferation and migration of COLO-16 cells without affecting the normal keratinocytes.
Furthermore, the inhibitory activity was found by exhibiting Zonula occludens (ZO)-1, inhibition of ZO-1 expression, and its failure to accumulate at cell junctions (ZO-1 and claudin-1) have been found to induce cancer progression.
In other words, lycopene inhibited the SCC cell line COLO-16 proliferation by enhancing the expression of the tight junction complexes that regulate the permeability of epithelial against cancer cells.
Additionally, cell cycle division proteins (JNK and ERK ) in the induction of mitogen associated with the decreasing levels of ZO-1 and claudin-1 were also inhibited by the injection of lycopene.
More precisely, lycopene inhibited the progression of human sSCC cell line COLO-16 by reducing the proteins involved in promoting cell cycle division and increasing cancer cell permeability and autophagy,
Based on the findings researchers said, "This study indicates that lycopene might be a useful chemopreventive agent against cSCC".
Taken together, lycopene may be considered supplements for the prevention and treatment of skin cancer, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene upregulates ZO-1 and downregulates claudin-1 through autophagy inhibition in the human cutaneous squamous cell carcinoma cell line COLO-16 by Bi S1,2, Li L1, Gu H1, Li M1, Xu S1, Bu W1, Zhang M1, Zhou Z2, Chen X. (PubMed)
(2) Suppressive effects of lycopene and β-carotene on the viability of the human esophageal squamous carcinoma cell line EC109 by Ngoc NB1,2, Lv P1,3, Zhao WE1. (PubMed)
#Anethole found in #Fennel Exerts a Orotective Effect Against Micro Imbalance in Initiated #GastrointestinalDisorder, Researchers Say
Kyle J. Norton
Fennel may have a potential and therapeutic effect in reduced risk, progression, and treatment of gastrointestinal dysbiosis, some scientists suggested.
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract, particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as a warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil on the risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in a reduced concentration of the growth of potential pathogens compared to the isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. Amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decreases levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180-day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut microflora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), diet accompanied with 2 mentioned mixed powder plants (0.5% of total diet), diet with TF mixed powder plant and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through an expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti-antimicrobial activity of the gut compared to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a functional herb for reduced risk, and progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP.(PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut microflora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE, AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
Fennel may have a potential and therapeutic effect in reduced risk, progression, and treatment of gastrointestinal dysbiosis, some scientists suggested.
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract, particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as a warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil on the risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in a reduced concentration of the growth of potential pathogens compared to the isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. Amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decreases levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180-day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut microflora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), diet accompanied with 2 mentioned mixed powder plants (0.5% of total diet), diet with TF mixed powder plant and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through an expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti-antimicrobial activity of the gut compared to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a functional herb for reduced risk, and progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP.(PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut microflora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE, AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
#Isothiocyanates (ITC) Found in #CruciferousVegetables Inhibit the Freeradical Induced Inflammation through Their Antioxidant Activity, Acccording to Studies
Kyle J. Norton
Inflammation is a natural expression by the immune system in induction of white blood cells for protect our body against infection with foreign organisms,
Cruciferous vegetables are a group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
In a randomized controlled trial in healthy young adults, isothiocyanates found in cruciferous vegetables exhibited anti-inflammatory effects through altered serum concentrations of interleukin (IL)-6, IL-8, C-reactive protein (CRP)), in increased increases in the presence of inflammation in the body tumor, and necrosis factor (TNF) α,, involved in systemic inflammation.
Intake of Cruciferous Vegetables has been shown to reduce the circulation of proinflammatory cytokines, namely IL-6 through inhibiting the expression of an abnormal function of gene Glutathione S-Transferase Theta 1(GSTT1) metabolism in lower levels of glutathione, the antioxidant with anti-inflammatory properties.
Dr. Navarro SL, the lead researcher said, " IL-6 concentrations were significantly lower on day 14 of (the double-dose cruciferous) (2xC) and (cruciferous plus apiaceous (carrot family) 1xC+A diets than with the basal diet,...respectively]" and " Twenty-four-hour urinary isothiocyanate excretion was not associated with any of the inflammation markers overall; however, IL-6 was inversely associated with total isothiocyanate excretion in GSTM1".
In support of the above study, isothiocyanates (ITC) from cruciferous vegetables showed to increase levels of serum of Glutathione S-transferases (GST), the enzymes that detoxify a broad range of free radicals in reduced risk of inflammation, particularly in GSTM1-null women.
Furthermore, the phytochemical also increased GSTA1/2, the antioxidant enzyme in GSTM1-null/GSTT1-null men.
Taken together, the intake of Cruciferous Vegetables regularly is associated to lower the effect of proinflammatory cytokines, particularly in adults with gene GSTT1.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults by Navarro SL1, Schwarz Y2, Song X2, Wang CY2, Chen C2, Trudo SP3, Kristal AR2, Kratz M2, Eaton DL4, Lampe JW2. (PubMed)
(2) Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes by Navarro SL1, Chang JL, Peterson S, Chen C, King IB, Schwarz Y, Li SS, Li L, Potter JD, Lampe JW. (PubMed)
Inflammation is a natural expression by the immune system in induction of white blood cells for protect our body against infection with foreign organisms,
Cruciferous vegetables are a group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
In a randomized controlled trial in healthy young adults, isothiocyanates found in cruciferous vegetables exhibited anti-inflammatory effects through altered serum concentrations of interleukin (IL)-6, IL-8, C-reactive protein (CRP)), in increased increases in the presence of inflammation in the body tumor, and necrosis factor (TNF) α,, involved in systemic inflammation.
Intake of Cruciferous Vegetables has been shown to reduce the circulation of proinflammatory cytokines, namely IL-6 through inhibiting the expression of an abnormal function of gene Glutathione S-Transferase Theta 1(GSTT1) metabolism in lower levels of glutathione, the antioxidant with anti-inflammatory properties.
Dr. Navarro SL, the lead researcher said, " IL-6 concentrations were significantly lower on day 14 of (the double-dose cruciferous) (2xC) and (cruciferous plus apiaceous (carrot family) 1xC+A diets than with the basal diet,...respectively]" and " Twenty-four-hour urinary isothiocyanate excretion was not associated with any of the inflammation markers overall; however, IL-6 was inversely associated with total isothiocyanate excretion in GSTM1".
In support of the above study, isothiocyanates (ITC) from cruciferous vegetables showed to increase levels of serum of Glutathione S-transferases (GST), the enzymes that detoxify a broad range of free radicals in reduced risk of inflammation, particularly in GSTM1-null women.
Furthermore, the phytochemical also increased GSTA1/2, the antioxidant enzyme in GSTM1-null/GSTT1-null men.
Taken together, the intake of Cruciferous Vegetables regularly is associated to lower the effect of proinflammatory cytokines, particularly in adults with gene GSTT1.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults by Navarro SL1, Schwarz Y2, Song X2, Wang CY2, Chen C2, Trudo SP3, Kristal AR2, Kratz M2, Eaton DL4, Lampe JW2. (PubMed)
(2) Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes by Navarro SL1, Chang JL, Peterson S, Chen C, King IB, Schwarz Y, Li SS, Li L, Potter JD, Lampe JW. (PubMed)
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