Kyle J. Norton
Inflammatory bowel disease is a condition characterized by long-term inflammation of the gut. The disease affects over 1.6 million Americans today.
The most common types of IBD are
*Crohn’s disease (CD) is an inflammation of any part of the digestive tract. Most cases of CD affect the tail end of the small intestine.
* Ulcerative colitis is an inflammation of the large intestine.
* Crohn's disease is a type of inflammatory bowel disease caused by inflammation in the gastrointestinal tract.
The exact cause of Crohn's disease is not identified. However, some researchers suggested that people with a compromised immune system and genetic preposition are prone to the disease onset compared to people who do not
The most common symptoms of Crohn's disease are abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.
Risk factors of Crohn's disease include aging, family and person history, ethnicity, smoking and long-term use of Nonsteroidal anti-inflammatory medications.
Conventionally, most cases of CD are treated by anti-inflammatory medications, corticosteroids, immunomodulators, and antibiotics.
According to the statistics by Crohn's & Colitis Foundation, the total number of new cases of Crohn's disease diagnosed each year was 10.7 per 100,000 people. In other words, approximately 33,000 new cases are diagnosed each year.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
In finding a potential phytochemical for the treatment of chronic inflammatory diseases, researchers examined the omega-3 supplementation by oral capsule for patients with Crohn's disease (CD).
The study included a total of 6 patients with CD in remission who participated in this open-label clinical trial and received one bottle (100 ml) of the test formulation (IMARK S®) daily for 28 days. After a 1-month washout period, patients ingested two bottles of the formulation daily for another 28 days.
According to the results of the anthropometric and blood tests,* There were no side effects with the quantity of the injection.
* The application did not alter the body weight and body mass index of the participants.
* Most importantly, according to the CD activity index, participants showed a decrease in their scores after ingesting one bottle of the formulation.
Based on the findings, researchers said, "Supplementation with an omega-3 emulsifying formulation can be safe and useful for maintaining remission in patients with CD and warrants further studies".
Taken together, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of Crohn's disease (CD), pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Safety of Emulsifying Lipid Formulation Containing Omega-3 Polyunsaturated Fatty Acids for Patients with Crohn's Disease by Yasueda A1, Shinzaki S2, Iijima H2, Mizushima T3, Nishimura J4, Hiyama S5, Ohno S1, Ito T. (PubMed)
Friday, 4 August 2023
#Lycopene, Processes Anti-diabetic Nephropathy by Inhibiting Advanced Glycation End Products #AGEs, Researchers Find
Kyle J. Norton
Diabetic nephropathy (diabetic kidney disease) is a complication of kidney damage in diabetes.
Long-term unmanaged hyperglycemia has been found to damage parts of the kidneys, leading to reduced kidney function in filter waste from the blood filters, resulting in a 'leaky' syndrome that allows protein into your urine.
Diabetic nephropathy is the 3 stages of kidney change in patients with diabetes. In this stage, patients may experience symptoms of abnormally elevated urinary albumin excretion, compared to the 15 and 300 μg/min in the baseline situation.
The progression of diabetic nephropathy that leads to an increased rate of albumin excretion is higher in patients with increased blood pressure.
The condition in the advanced stage can lead to symptoms of worsening blood pressure, protein in the urine, swelling of feet, ankles, hands or eyes, increased need to urinate, loss of appetite, nausea and vomiting, fatigue and persistent itching.
In severe cases, patients may also experience symptoms of confusion or difficulty concentrating.
More importantly, if high blood pressure is left uncontrolled, diabetic nephropathy can induce persistent proteinuria >0.5 g/ 24 h that furtherly declines the renal function with the mean fall rate being around 1 ml/min/mo.
In other words, by treating hypertension and hyperglycemia in patients with diabetes, the progression of diabetics kidney disease may be slowed.
Some researchers suggested that by maintaining healthy blood glucose levels and keeping them within the target range and a change of healthful diet accompanied by moderate exercise, diabetic nephropathy can be control
Dr. Chijoke Onyenwenyi, "Kidney disease is common in patients with type 1 and type 2 diabetes mellitus and is associated with adverse health outcomes, including progression to end-stage renal disease. In the general population, adherence to a healthy lifestyle is known to reduce the risk of cardiovascular events and death".
And, "Among individuals with diabetic kidney disease, modifications in lifestyle factors, including diet, physical activity, smoking habits, and body mass index, represent a promising cost-effective therapeutic adjunct to pharmacologic treatment of kidney disease incidence and progression".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potent compound for the treatment of diabetic complications, researchers examined the effects of lycopene, a carotenoid, on oxidative stress-induced progression of diabetic nephropathy.
According to the tested assays, lycopene inhibited the menace ad oxidative stress and stress markers associated with advanced glycation end products (AGEs) both in vitro and in vivo.
Furthermore, lycopene decelerated the ribose-induced AGE formation in the normal adult human kidney. (HK-2) cells and in rat kidneys thereby inhibiting the expression RAGE involved in the inflammatory response, leading to reduced levels of nuclear factor κB (NFκB) and matrix metalloproteinase 2 (MMP 2) expressions.
Where nuclear factor κB (NFκB) and matrix metalloproteinase 2 (MMP 2) expressions. are associated with cytokine production under oxidative stress.
Most importantly, nephropathy (DN) induced by the administration of ribose was totally inhibited by the injection of lycopene.
Based on the findings, researchers wrote, "lycopene provides protection against the development of diabetic nephropathy and ameliorates renal function by halting AGE-RAGE axis".
Taken together, lycopene found in tomatoes may be considered a supplement for protection against the risk of diabetic nephropathy in diabetics, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene powers the inhibition of glycation-induced diabetic nephropathy: a novel approach to halting the AGE-RAGE axis menace by Tabrez S1, Al-Shali KZ2, Ahmad S. (PubMed)
(2) Beneficial effect of lycopene on anti-diabetic nephropathy through diminishing inflammatory response and oxidative stress by Guo Y1, Liu Y, Wang Y. (PubMed)
(3) Impact of Lifestyle Modification on Diabetic Kidney Disease by Chijoke Onyenwenyi, MD and Ana C. Ricardo, MD, MPH. (PMC)
Diabetic nephropathy (diabetic kidney disease) is a complication of kidney damage in diabetes.
Long-term unmanaged hyperglycemia has been found to damage parts of the kidneys, leading to reduced kidney function in filter waste from the blood filters, resulting in a 'leaky' syndrome that allows protein into your urine.
Diabetic nephropathy is the 3 stages of kidney change in patients with diabetes. In this stage, patients may experience symptoms of abnormally elevated urinary albumin excretion, compared to the 15 and 300 μg/min in the baseline situation.
The progression of diabetic nephropathy that leads to an increased rate of albumin excretion is higher in patients with increased blood pressure.
The condition in the advanced stage can lead to symptoms of worsening blood pressure, protein in the urine, swelling of feet, ankles, hands or eyes, increased need to urinate, loss of appetite, nausea and vomiting, fatigue and persistent itching.
In severe cases, patients may also experience symptoms of confusion or difficulty concentrating.
More importantly, if high blood pressure is left uncontrolled, diabetic nephropathy can induce persistent proteinuria >0.5 g/ 24 h that furtherly declines the renal function with the mean fall rate being around 1 ml/min/mo.
In other words, by treating hypertension and hyperglycemia in patients with diabetes, the progression of diabetics kidney disease may be slowed.
Some researchers suggested that by maintaining healthy blood glucose levels and keeping them within the target range and a change of healthful diet accompanied by moderate exercise, diabetic nephropathy can be control
Dr. Chijoke Onyenwenyi, "Kidney disease is common in patients with type 1 and type 2 diabetes mellitus and is associated with adverse health outcomes, including progression to end-stage renal disease. In the general population, adherence to a healthy lifestyle is known to reduce the risk of cardiovascular events and death".
And, "Among individuals with diabetic kidney disease, modifications in lifestyle factors, including diet, physical activity, smoking habits, and body mass index, represent a promising cost-effective therapeutic adjunct to pharmacologic treatment of kidney disease incidence and progression".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potent compound for the treatment of diabetic complications, researchers examined the effects of lycopene, a carotenoid, on oxidative stress-induced progression of diabetic nephropathy.
According to the tested assays, lycopene inhibited the menace ad oxidative stress and stress markers associated with advanced glycation end products (AGEs) both in vitro and in vivo.
Furthermore, lycopene decelerated the ribose-induced AGE formation in the normal adult human kidney. (HK-2) cells and in rat kidneys thereby inhibiting the expression RAGE involved in the inflammatory response, leading to reduced levels of nuclear factor κB (NFκB) and matrix metalloproteinase 2 (MMP 2) expressions.
Where nuclear factor κB (NFκB) and matrix metalloproteinase 2 (MMP 2) expressions. are associated with cytokine production under oxidative stress.
Most importantly, nephropathy (DN) induced by the administration of ribose was totally inhibited by the injection of lycopene.
Based on the findings, researchers wrote, "lycopene provides protection against the development of diabetic nephropathy and ameliorates renal function by halting AGE-RAGE axis".
Taken together, lycopene found in tomatoes may be considered a supplement for protection against the risk of diabetic nephropathy in diabetics, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene powers the inhibition of glycation-induced diabetic nephropathy: a novel approach to halting the AGE-RAGE axis menace by Tabrez S1, Al-Shali KZ2, Ahmad S. (PubMed)
(2) Beneficial effect of lycopene on anti-diabetic nephropathy through diminishing inflammatory response and oxidative stress by Guo Y1, Liu Y, Wang Y. (PubMed)
(3) Impact of Lifestyle Modification on Diabetic Kidney Disease by Chijoke Onyenwenyi, MD and Ana C. Ricardo, MD, MPH. (PMC)
#Broccoli's Sulforaphane (SF) Prosesses Anti Kidney Toxicity Induced by Chemo Drug, According to Studies
Kyle J. Norton
Kidneys are 2 bean-shaped organs found on the left and right side of the retroperitoneal space in the body.
The function of the kidneys is to filter blood and control fluids. They are the second detoxed organs besides the liver and skin.
Due to millions of tiny filters called nephrons in each kidney, people may not experience any kidney dysfunction symptoms at an early stage.
Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in cases, complete loss of kidney function such as kidney failure.
Believe it or not, in the US, the leading causes of kidney failure and the end stage of chronic kidney diseases are diabetes and high blood pressure.
Chemotherapy is a drug treatment that kills cancer cells by inducing cytotoxicity. Most cases of chemotherapy have been found to cause severe side effects on the patient, including fatigue, loss of appetite, nausea, bowel issues such as constipation or diarrhea, hair loss, mouth sores, and skin and nail problems.
Chemo drugs have also been shown to induce nephrotoxicity, by increasing the production of ROS and inhibiting several antioxidant enzymes to orchestrate kidney oxidative stress injury.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding a potential plant that processes anti-kidney toxicity induced by chemo-drugs, researchers examined the effects of sulforaphane (SF), a natural constituent of cruciferous vegetables such as broccoli, on Cisplatin (cis-diamminedichloroplatinum II, CIS) nephropathy.
In rodents, before treatment with FN, cisplatin therapy triggered marked activation of stress signaling pathways to promote cancer cell death in the kidney by increasing the DNA fragmentation, apoptotic proteins,
Furthermore, CIS also exhibited the terminal associated with attenuation of various prosurvival signaling pathways and increased levels of the pro-inflammatory cytokines in the kidney.
In other words, the injection of CIS not only induced kidney injury but also caused damage to the death of the kidney cells, through several aforementioned mechanisms.
After the administration of SF, all these effects were significantly attenuated by the pretreatment of rodents with SFN.
Based on the evidence, researchers wrote, " SFN is able to prevent the CIS-induced renal injury by modulating these pathways, providing a novel approach for preventing this devastating complication of chemotherapy".
Taken together, the consequences of these results suggest that the broccoli process has the potential anti-side effect of CIS in the induction of kidney toxicity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy by Guerrero-Beltrán CE1, Mukhopadhyay P, Horváth B, Rajesh M, Tapia E, García-Torres I, Pedraza-Chaverri J, Pacher P. (PubMed)
Kidneys are 2 bean-shaped organs found on the left and right side of the retroperitoneal space in the body.
The function of the kidneys is to filter blood and control fluids. They are the second detoxed organs besides the liver and skin.
Due to millions of tiny filters called nephrons in each kidney, people may not experience any kidney dysfunction symptoms at an early stage.
Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in cases, complete loss of kidney function such as kidney failure.
Believe it or not, in the US, the leading causes of kidney failure and the end stage of chronic kidney diseases are diabetes and high blood pressure.
Chemotherapy is a drug treatment that kills cancer cells by inducing cytotoxicity. Most cases of chemotherapy have been found to cause severe side effects on the patient, including fatigue, loss of appetite, nausea, bowel issues such as constipation or diarrhea, hair loss, mouth sores, and skin and nail problems.
Chemo drugs have also been shown to induce nephrotoxicity, by increasing the production of ROS and inhibiting several antioxidant enzymes to orchestrate kidney oxidative stress injury.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
In finding a potential plant that processes anti-kidney toxicity induced by chemo-drugs, researchers examined the effects of sulforaphane (SF), a natural constituent of cruciferous vegetables such as broccoli, on Cisplatin (cis-diamminedichloroplatinum II, CIS) nephropathy.
In rodents, before treatment with FN, cisplatin therapy triggered marked activation of stress signaling pathways to promote cancer cell death in the kidney by increasing the DNA fragmentation, apoptotic proteins,
Furthermore, CIS also exhibited the terminal associated with attenuation of various prosurvival signaling pathways and increased levels of the pro-inflammatory cytokines in the kidney.
In other words, the injection of CIS not only induced kidney injury but also caused damage to the death of the kidney cells, through several aforementioned mechanisms.
After the administration of SF, all these effects were significantly attenuated by the pretreatment of rodents with SFN.
Based on the evidence, researchers wrote, " SFN is able to prevent the CIS-induced renal injury by modulating these pathways, providing a novel approach for preventing this devastating complication of chemotherapy".
Taken together, the consequences of these results suggest that the broccoli process has the potential anti-side effect of CIS in the induction of kidney toxicity, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy by Guerrero-Beltrán CE1, Mukhopadhyay P, Horváth B, Rajesh M, Tapia E, García-Torres I, Pedraza-Chaverri J, Pacher P. (PubMed)
#Antioxidant #Lycopene Inhibits Radiation-induced Acute Esophageal Toxicity and Esophagitis, According to Studies
Kyle J. Norton
Esophagitis or heartburn or gastroesophageal reflux disease (GERD). is a condition characterized by the going backup of acidic stomach contents to the esophagus?
Most cases of esophagitis are happened immediately after eating causing a burning sensation or pain in the lower chest area.
According to the statistics, in the US, approximately, 20% of people with acid reflux will develop esophagitis.
More than 65% of people who suffer from acid reflux are 40 years old or older. And, 15 to 30 5 of the U.S. population has esophagitis
There is no single cause of esophagitis. Epidemiologically, eating large meals or lying down right after a meal, snacking close to bedtime, smoking, being overweight or obese, overeating certain foods such as citrus, tomato, chocolate, mint, garlic, onions, or spicy or fatty foods are some prevalent factors associated with the risk of esophagitis
First-time pregnant women may also experience esophagitis caused by increasing levels of hormones combined with pressure from the growing fetus.
Furthermore, long-term intake of certain medications such as bronchodilators for asthma, progestin for birth control or to treat abnormal menstrual bleeding, sedatives for insomnia and anxiety, and calcium channel blockers for high blood pressure.
Dr. Zeynel Mungan and colleagues in examing the medication risk of esophagitis wrote, "Gastroesophageal reflux disease (GERD), which is common in many communities, is associated with structural factors, eating habits, and the use of certain drugs".
And, "The use of such drugs can lead to the emergence of GERD and can also exacerbate existing reflux symptoms. These drugs can contribute to GERD by directly causing mucosal damage, by reducing lower esophageal sphincter pressure (LESP), or by affecting esophagogastric motility".
Therefore, if you currently taking some of the aforementioned medications, please make sure that you know all the side effects for preventive measures.
Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of esophagitis, researchers examined the role of lycopene (L) on radiation-induced acute esophageal toxicity in an animal model.
60 Wistar albino rats.selected to the study were divided into five groups: control, L, radiotherapy (RT), L before RT (L + RT), and L before and after RT (L + RT + L). 6 mg/kg bw/day with L administered 7 days in the L group, 7 days before RT in the L + RT group, and 7 days before and after in the L + RT + L group.
According to the tested analysis, L levels were significantly higher in the L-receiving groups, compared to the RT group.
Esophagitis was significantly worse in the RT group than in the non-RT group. Injection of lycopene in the L + RT and the L + RT + L groups showed better results than the RT group.
Compared to the RT group, grade 2-3 degenerative changes-necrosis and vacuole formation were significantly lesser in the L + RT and the L + RT + L groups.
Furthermore, subepithelial bulla formation and inflammation in the L + RT and the L + RT + L groups were also significantly decreased compared to the RT group.
Moreover, L + RT + L groups exerted the highest decrease to regeneration-mitosis compared to a moderate decrease in the L + RT group, compared to RT groups.
Taken together, lycopene found in tomatoes may be considered supplements for the prevention and treatment of esophagitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene in the Prevention of Radiation-Induced Esophagitis by Coskun H1, Andic F1, Daglıoglu YK2, Doran F3, Sahin K4, Tunalı C1, Kucuk O. (PubMed)
(2) Which drugs are risk factors for the development of gastroesophageal reflux disease? by Mungan Z, Pınarbaşı Şimşek B. (PubMed)
Esophagitis or heartburn or gastroesophageal reflux disease (GERD). is a condition characterized by the going backup of acidic stomach contents to the esophagus?
Most cases of esophagitis are happened immediately after eating causing a burning sensation or pain in the lower chest area.
According to the statistics, in the US, approximately, 20% of people with acid reflux will develop esophagitis.
More than 65% of people who suffer from acid reflux are 40 years old or older. And, 15 to 30 5 of the U.S. population has esophagitis
There is no single cause of esophagitis. Epidemiologically, eating large meals or lying down right after a meal, snacking close to bedtime, smoking, being overweight or obese, overeating certain foods such as citrus, tomato, chocolate, mint, garlic, onions, or spicy or fatty foods are some prevalent factors associated with the risk of esophagitis
First-time pregnant women may also experience esophagitis caused by increasing levels of hormones combined with pressure from the growing fetus.
Furthermore, long-term intake of certain medications such as bronchodilators for asthma, progestin for birth control or to treat abnormal menstrual bleeding, sedatives for insomnia and anxiety, and calcium channel blockers for high blood pressure.
Dr. Zeynel Mungan and colleagues in examing the medication risk of esophagitis wrote, "Gastroesophageal reflux disease (GERD), which is common in many communities, is associated with structural factors, eating habits, and the use of certain drugs".
And, "The use of such drugs can lead to the emergence of GERD and can also exacerbate existing reflux symptoms. These drugs can contribute to GERD by directly causing mucosal damage, by reducing lower esophageal sphincter pressure (LESP), or by affecting esophagogastric motility".
Therefore, if you currently taking some of the aforementioned medications, please make sure that you know all the side effects for preventive measures.
Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of esophagitis, researchers examined the role of lycopene (L) on radiation-induced acute esophageal toxicity in an animal model.
60 Wistar albino rats.selected to the study were divided into five groups: control, L, radiotherapy (RT), L before RT (L + RT), and L before and after RT (L + RT + L). 6 mg/kg bw/day with L administered 7 days in the L group, 7 days before RT in the L + RT group, and 7 days before and after in the L + RT + L group.
According to the tested analysis, L levels were significantly higher in the L-receiving groups, compared to the RT group.
Esophagitis was significantly worse in the RT group than in the non-RT group. Injection of lycopene in the L + RT and the L + RT + L groups showed better results than the RT group.
Compared to the RT group, grade 2-3 degenerative changes-necrosis and vacuole formation were significantly lesser in the L + RT and the L + RT + L groups.
Furthermore, subepithelial bulla formation and inflammation in the L + RT and the L + RT + L groups were also significantly decreased compared to the RT group.
Moreover, L + RT + L groups exerted the highest decrease to regeneration-mitosis compared to a moderate decrease in the L + RT group, compared to RT groups.
Taken together, lycopene found in tomatoes may be considered supplements for the prevention and treatment of esophagitis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lycopene in the Prevention of Radiation-Induced Esophagitis by Coskun H1, Andic F1, Daglıoglu YK2, Doran F3, Sahin K4, Tunalı C1, Kucuk O. (PubMed)
(2) Which drugs are risk factors for the development of gastroesophageal reflux disease? by Mungan Z, Pınarbaşı Şimşek B. (PubMed)
#BetaSitosterol Regulates mRNA and Protein Expression Against the Onset of #LiverFibrosis in Vitro and Vivo
Kyle J. Norton
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process associated with responding to injury.
In some cases, the forming of scaring is also caused by the overproduction of proinflammatory cytokines and/or interruption in the stage of injury recovery.
Liver fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the liver. In other words, hepatic fibrosis is a condition in which a portion of the liver was affected by scar formation.
The exact causes of liver fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of liver fibrosis.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of severe scarring of the liver and life-threatening liver disease, including liver cancer.
The most common scale to grade the stage of liver fibrosis is the METAVIR scoring system. By examing the grade and stage of liver fibrosis of patients, their doctors can now determine the degree of severity to which patients' liver is affected.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the β-sitosterol, a cholesterol-like phytosterol, which is widely distributed in the plant kingdom. the anti-fibrotic effect on human hepatic stellate cell (HSC) model and dimethylnitrosamine (DMN)-induced mouse hepatic fibrosis model.
According to the results of the analysis of the hepato-fibrotic effect of β-sitosterol, at both of the mRNA and protein levels,
* β-sitosterol inhibited scar formation by down-regulating the mRNA and protein expression levels of collagen-1 and α-smooth muscle actin (α-SMA), a key biomarker for liver fibrosis and in activated HSC.
* Furthermore, oral administration of the β-sitosterol successfully alleviated the DMN-induced mouse liver damage and prevented collagen accumulation.
In other words, β-sitosterol exerted liver cell-protective effects against the liver damage and parameters associated with the onset of liver fibrosis.
Based on the findings, researchers said, " the effect of β-sitosterol on the TGF-β -or DMN-induced hepatofibrosis. Hence, we demonstrate the β-sitosterol as a potential therapeutic agent for the hepatofibrosis".
Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of liver fibrosis, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of β-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis by Kim KS, Yang HJ, Lee JY, Na YC, Kwon SY, Kim YC, Lee JH1, Jang HJ. (PubMed)
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process associated with responding to injury.
In some cases, the forming of scaring is also caused by the overproduction of proinflammatory cytokines and/or interruption in the stage of injury recovery.
Liver fibrosis is a condition characterized by overly exuberant wound healing causing excessive connective tissue builds up in the liver. In other words, hepatic fibrosis is a condition in which a portion of the liver was affected by scar formation.
The exact causes of liver fibrosis are unknown. However, certain risk factors such as repeated liver injury caused by a virus infection, and a blockage in the bile ducts are found to elaborate on the onset of liver fibrosis.
Long-term untreated liver fibrosis can lead to cirrhosis, a condition of severe scarring of the liver and life-threatening liver disease, including liver cancer.
The most common scale to grade the stage of liver fibrosis is the METAVIR scoring system. By examing the grade and stage of liver fibrosis of patients, their doctors can now determine the degree of severity to which patients' liver is affected.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the β-sitosterol, a cholesterol-like phytosterol, which is widely distributed in the plant kingdom. the anti-fibrotic effect on human hepatic stellate cell (HSC) model and dimethylnitrosamine (DMN)-induced mouse hepatic fibrosis model.
According to the results of the analysis of the hepato-fibrotic effect of β-sitosterol, at both of the mRNA and protein levels,
* β-sitosterol inhibited scar formation by down-regulating the mRNA and protein expression levels of collagen-1 and α-smooth muscle actin (α-SMA), a key biomarker for liver fibrosis and in activated HSC.
* Furthermore, oral administration of the β-sitosterol successfully alleviated the DMN-induced mouse liver damage and prevented collagen accumulation.
In other words, β-sitosterol exerted liver cell-protective effects against the liver damage and parameters associated with the onset of liver fibrosis.
Based on the findings, researchers said, " the effect of β-sitosterol on the TGF-β -or DMN-induced hepatofibrosis. Hence, we demonstrate the β-sitosterol as a potential therapeutic agent for the hepatofibrosis".
Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of liver fibrosis, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of β-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis by Kim KS, Yang HJ, Lee JY, Na YC, Kwon SY, Kim YC, Lee JH1, Jang HJ. (PubMed)
#Turmeric Inhibits the Adiponectin Expression Against the Onset of Non-Small Cell Lung Cancer Cells In Vitro
Kyle J. Norton
Cancer is a class of medical and chronic diseases caused by irregular cell growth due to the alternation of cell DNA in the tissue of a specific organ.
Cancer cell that grows and multiply disorderly and uncontrollably over time can induce the forming of tumor after penetrating deeper layers of the infected organ tissue.
At the advanced stage, most invasive tumors can travel a distance away to infect other organs in the body via lymph or blood.
The lung is a vital organ located near the backbone on either side of the heart with the function of inhaling oxygen from the air before passing them to other parts of the body and exhaling carbon dioxide from the bloodstream.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells.
According to the statistics provided by the American Cancer Society, lung cancer is by far the leading cause of cancer death among both men and women in the US. Believe it or not, each year, more people die of lung cancer than of colon, breast, and prostate cancers combined.
Most people diagnosed with lung cancer are 65 or older, compared to a very small number of those younger than 45.
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, that usually grows and spreads methodically and predictably including
* Squamous-cell carcinoma is a type of NSCLC often found in an outer area of the lung.
* Large-cell carcinoma is a type of NSCLC found in the center of the lung by an air tube.
* Adenocarcinoma is the type of NSCLC found in any part of the lung.
Dr. Paris D. Makrantonakis, the lead scientist in examined the correlation of NSCLC risk and treatment in the elderly wrote, "The population is aging both in developing and developed countries. What is clear is that currently, over 50% of all patients with non-small cell lung cancer (NSCLC) are 65 years of age or older".
And, "recently published studies have focused on the issue and have provided strong evidence of improved progression-free survival, overall survival, and quality of life in elderly patients with appropriately treated NSCLC".
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential ingredient for the treatment of non-small cell lung cancer (NSCLC), researchers examined the effect of curcumin on the expression of adiponectin in paired tumors and normal lung tissues from 77 patients with NSCLC.
Epidemiologically, patients with low adiponectin expression ratio (<1) were found to have significantly longer survival time compared to those with a high expression ratio and adiponectin may be a prognostic indicator of NSCLC.
Administration of curcumin showed to inhibit the migratory and invasive ability of A549 cells by inhibiting the adiponectin expression.
Furthermore, Curcumin treatment also inhibited the in vivo tumor growth of A549 cells associated with the adiponectin expression.
More precisely, the efficacy of curcumin that inhibits the NSCLC was attributed to the mediation of pathways involved in promoting tumor invasion.
Additionally, according to the Shanxi Province Tumor Hospital study, curcumin inhibited the A549 cell proliferation also was found by decreasing intracellular ROS levels and increasing SOD and gamma-glutamylcysteine synthetase (γ-GCS) activity passcode with cancer cells apoptosis.
The results strongly suggested that curcumin-induced reduction of A549 viability. by inhibiting the expression of oxidative stress.
Taken together, turmeric-processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of non-small cell lung cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin Inhibits Non-Small Cell Lung Cancer Cells Metastasis through the Adiponectin/NF-κb/MMPs Signaling Pathway by Tsai JR1,2, Liu PL1, Chen YH3, Chou SH1,4, Cheng YJ5, Hwang JJ1,2, Chong IW. (PubMed)
(2) Curcumin inhibits the growth via Wnt/β-catenin pathway in non-small-cell lung cancer cells by Wang JY1, Wang X, Wang XJ, Zheng BZ, Wang Y, Wang X, Liang B. (PubMed)
(3) Non-Small Cell Lung Cancer in the Elderly by Paris D. Makrantonakis, Eleni Galani, and Peter G. Harper. (The Oncologist)
Cancer is a class of medical and chronic diseases caused by irregular cell growth due to the alternation of cell DNA in the tissue of a specific organ.
Cancer cell that grows and multiply disorderly and uncontrollably over time can induce the forming of tumor after penetrating deeper layers of the infected organ tissue.
At the advanced stage, most invasive tumors can travel a distance away to infect other organs in the body via lymph or blood.
The lung is a vital organ located near the backbone on either side of the heart with the function of inhaling oxygen from the air before passing them to other parts of the body and exhaling carbon dioxide from the bloodstream.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells.
According to the statistics provided by the American Cancer Society, lung cancer is by far the leading cause of cancer death among both men and women in the US. Believe it or not, each year, more people die of lung cancer than of colon, breast, and prostate cancers combined.
Most people diagnosed with lung cancer are 65 or older, compared to a very small number of those younger than 45.
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, that usually grows and spreads methodically and predictably including
* Squamous-cell carcinoma is a type of NSCLC often found in an outer area of the lung.
* Large-cell carcinoma is a type of NSCLC found in the center of the lung by an air tube.
* Adenocarcinoma is the type of NSCLC found in any part of the lung.
Dr. Paris D. Makrantonakis, the lead scientist in examined the correlation of NSCLC risk and treatment in the elderly wrote, "The population is aging both in developing and developed countries. What is clear is that currently, over 50% of all patients with non-small cell lung cancer (NSCLC) are 65 years of age or older".
And, "recently published studies have focused on the issue and have provided strong evidence of improved progression-free survival, overall survival, and quality of life in elderly patients with appropriately treated NSCLC".
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential ingredient for the treatment of non-small cell lung cancer (NSCLC), researchers examined the effect of curcumin on the expression of adiponectin in paired tumors and normal lung tissues from 77 patients with NSCLC.
Epidemiologically, patients with low adiponectin expression ratio (<1) were found to have significantly longer survival time compared to those with a high expression ratio and adiponectin may be a prognostic indicator of NSCLC.
Administration of curcumin showed to inhibit the migratory and invasive ability of A549 cells by inhibiting the adiponectin expression.
Furthermore, Curcumin treatment also inhibited the in vivo tumor growth of A549 cells associated with the adiponectin expression.
More precisely, the efficacy of curcumin that inhibits the NSCLC was attributed to the mediation of pathways involved in promoting tumor invasion.
Additionally, according to the Shanxi Province Tumor Hospital study, curcumin inhibited the A549 cell proliferation also was found by decreasing intracellular ROS levels and increasing SOD and gamma-glutamylcysteine synthetase (γ-GCS) activity passcode with cancer cells apoptosis.
The results strongly suggested that curcumin-induced reduction of A549 viability. by inhibiting the expression of oxidative stress.
Taken together, turmeric-processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of non-small cell lung cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin Inhibits Non-Small Cell Lung Cancer Cells Metastasis through the Adiponectin/NF-κb/MMPs Signaling Pathway by Tsai JR1,2, Liu PL1, Chen YH3, Chou SH1,4, Cheng YJ5, Hwang JJ1,2, Chong IW. (PubMed)
(2) Curcumin inhibits the growth via Wnt/β-catenin pathway in non-small-cell lung cancer cells by Wang JY1, Wang X, Wang XJ, Zheng BZ, Wang Y, Wang X, Liang B. (PubMed)
(3) Non-Small Cell Lung Cancer in the Elderly by Paris D. Makrantonakis, Eleni Galani, and Peter G. Harper. (The Oncologist)
#Omega 3 Fatty Acids Improve the Immune Function by Regulating Immunoregulatory Cytokines, According to Studies
Kyle J. Norton
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, viruses, parasites, etc., and tumor cells, including irregular cell growth, and cancer cells to keep us healthy.
In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.
Although the immune system has done a great job in protecting us against foreign invasion, unfortunately, during the process of their functions, they may induce the production of free radicals and a chain of free radicals that can be harmful to our body.
Immunomodulatory activity is an action that improves the underactive immune function susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, depending on the substances that affect the immunomodulatory process, some may improve the immune function by modulating the genes involved in immune responses and protect the immune system against toxins or immunotoxic effects such as abnormal allergic reactions, others such as heavy metals can induce opposite effects.
In normal immunity, active immunity may also be artificially acquired active immunity is caused by the injection of the vaccine, a substance that contains antigen, and passive immunity is an auto-response of the immune system against infection through the production of antigen.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
In finding a potential phytochemical for the improvement of immune functioning, researchers examined the long-chain n-3 PUFAs (LCPUFAs) anti-atopic disease risk in infants.
The study included pregnant Sprague-Dawley rats randomly assigned to consume either SDA (3 g SDA/100 g fat) or a control (no SDA) diet, 5 d before parturition and through lactation (21 d).
Additionally, for oral tolerance (OT) treatment, 10-d-old pups were fed ovalbumin (Ova; 200 μL of 8 mg/mL) or placebo daily for 5 d. At 21 d,
According to the experimental results of pups (both sexes) that were weaned to their respective maternal diet until 6 wk of age and killed, the SDA-enriched maternal diet showed higher levels of plasma phospholipid (PL) EPA (15 times higher), docosapentaenoic acid (DPA; 3 times higher), and DHA (1.3 times higher) content in 3-wk-old pups, accompanied by higher B-cell function [plasma ovalbumin-specific IgG1, compared with the control diet.
Furthermore, compared with pups fed a control diet, the splenocytes from pups fed with the SDA diet had more (23%) helper T (Th) cells (CD3+CD4+) and activated (12%) Th cells (CD4+CD28+) (P < 0.02) than controls.
Moreover, at 6 wk, the SDA group stimulated ex vivo with LPS, also had 30% more CD4+CD25+ splenocytes and produced less inflammatory IL-6 (50%) and TNF-α (30%) and more immunoregulatory IL-10 (45%) cytokines, compared to the control group.
However, the splenocytes and plasma PLs from the 6-week-old SDA group had more EPA (2x) and DPA (3.5x) (P < 0.05), but not DHA, compared to the control group.
Additionally, the Ova-exposed group also had less (30%) plasma Ova-IgG1 than the placebo group.
Based on the findings, researchers said, "Feeding SDA during lactation and weaning altered immune responses in directions believed to be beneficial".
Taken altogether, Omega-3 fatty acids may be considered a functional food for the improvement of the immune response, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Feeding a Bioactive Oil Enriched in Stearidonic Acid during Early Life Influences Immune System Maturation in Neonatal Sprague-Dawley Rats by Patel D1, Goruk S1, Newell M1, Chen G1, Richard C1, Field CJ. (PubMed)
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, viruses, parasites, etc., and tumor cells, including irregular cell growth, and cancer cells to keep us healthy.
In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.
Although the immune system has done a great job in protecting us against foreign invasion, unfortunately, during the process of their functions, they may induce the production of free radicals and a chain of free radicals that can be harmful to our body.
Immunomodulatory activity is an action that improves the underactive immune function susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, depending on the substances that affect the immunomodulatory process, some may improve the immune function by modulating the genes involved in immune responses and protect the immune system against toxins or immunotoxic effects such as abnormal allergic reactions, others such as heavy metals can induce opposite effects.
In normal immunity, active immunity may also be artificially acquired active immunity is caused by the injection of the vaccine, a substance that contains antigen, and passive immunity is an auto-response of the immune system against infection through the production of antigen.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
In finding a potential phytochemical for the improvement of immune functioning, researchers examined the long-chain n-3 PUFAs (LCPUFAs) anti-atopic disease risk in infants.
The study included pregnant Sprague-Dawley rats randomly assigned to consume either SDA (3 g SDA/100 g fat) or a control (no SDA) diet, 5 d before parturition and through lactation (21 d).
Additionally, for oral tolerance (OT) treatment, 10-d-old pups were fed ovalbumin (Ova; 200 μL of 8 mg/mL) or placebo daily for 5 d. At 21 d,
According to the experimental results of pups (both sexes) that were weaned to their respective maternal diet until 6 wk of age and killed, the SDA-enriched maternal diet showed higher levels of plasma phospholipid (PL) EPA (15 times higher), docosapentaenoic acid (DPA; 3 times higher), and DHA (1.3 times higher) content in 3-wk-old pups, accompanied by higher B-cell function [plasma ovalbumin-specific IgG1, compared with the control diet.
Furthermore, compared with pups fed a control diet, the splenocytes from pups fed with the SDA diet had more (23%) helper T (Th) cells (CD3+CD4+) and activated (12%) Th cells (CD4+CD28+) (P < 0.02) than controls.
Moreover, at 6 wk, the SDA group stimulated ex vivo with LPS, also had 30% more CD4+CD25+ splenocytes and produced less inflammatory IL-6 (50%) and TNF-α (30%) and more immunoregulatory IL-10 (45%) cytokines, compared to the control group.
However, the splenocytes and plasma PLs from the 6-week-old SDA group had more EPA (2x) and DPA (3.5x) (P < 0.05), but not DHA, compared to the control group.
Additionally, the Ova-exposed group also had less (30%) plasma Ova-IgG1 than the placebo group.
Based on the findings, researchers said, "Feeding SDA during lactation and weaning altered immune responses in directions believed to be beneficial".
Taken altogether, Omega-3 fatty acids may be considered a functional food for the improvement of the immune response, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Feeding a Bioactive Oil Enriched in Stearidonic Acid during Early Life Influences Immune System Maturation in Neonatal Sprague-Dawley Rats by Patel D1, Goruk S1, Newell M1, Chen G1, Richard C1, Field CJ. (PubMed)
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