#TopicalLeek Cream Processes Anti-Symptomatic Hemorrhoid Property Compared to Standard Medicines, Researchers Say

Kyle J. Norton

Hemorrhoids, also called piles are a common condition characterized by swollen veins in the anus and lower rectum.
Symptomatic hemorrhoidal tissues located above the dentate line are associated with the development of internal hemorrhoids that induce bleeding and prolapse.

The causes of hemorrhoids are unknown.

However, some researchers suggested that straining during bowel movements, a prolonged period of sitting due to the occupation that induces increased pressure on these veins are associated with the early onset of the condition.

In women, a pregnancy that causes pressure on the anus and swollen veins and lower rectum veins may also increase the risk of hemorrhoids.

According to statistics, a quarter of the adult population in the US has hemorrhoids developed at some point in their lives.

Most patients with hemorrhoids do not experience any symptoms. But in some infectious cases, hemorrhoids may induce symptoms of itching, discomfort, and bleeding.

Please be aware that some internal hemorrhoids can grow so large that they stick out of the anus. Prolapsed hemorrhoids, most of the time may require surgery to heal.

Dr. Seok-Gyu Song, the lead scientist wrote, "The traditional therapeutic strategies of medicine include surgical, as well as non-surgical, treatment. To alleviate symptoms caused by hemorrhoids, oral treatments, such as fiber, suppositories, and Sitz baths have been applied to patients".

And, "Other non-surgical treatments, such as infrared photocoagulation, injection sclerotherapy, and rubber band ligation have been used to fixate hemorrhoid's cushion. If non-surgical treatment has no effect, surgical treatments, such as a hemorrhoidectomy, procedure for prolapsed hemorrhoids, and transanal hemorrhoidal dearterialization are used".

Leek is a genius of Allium, belongings to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed and usually reach maturity in the autumn months, and have few pest or disease problems.

In finding a potential plant for the treatment of swollen veins. researchers compared the effects of topical herbal formulations and Allium ampeloprasum subsp iranicum (Leek) anti-hemorrhoidal activity.

According to the results of 20 patients with symptomatic hemorrhoids that were randomly allocated to receive the topical leek extract cream or standard anti-hemorrhoid cream for 3 weeks,* There was a significant decrease in the grade of bleeding severity and defecation discomfort in both the leek and anti hemorrhoid cream groups after the intervention.
* There was no significant change in pain scores.

* There was no significant difference between the leek and anti-hemorrhoid cream groups with regard to mean changes in outcome measures.

Collectively, researchers said, "This pilot study showed that the topical use of leek cream can be as effective as a standard anti-hemorrhoid cream".


Taken together, leeks may be considered a functional food for the prevention and treatment of symptomatic hemorrhoids, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Topical Allium ampeloprasum subsp Iranicum (Leek) extract cream in patients with symptomatic hemorrhoids: a pilot randomized and controlled clinical trial by Mosavat SH1, Ghahramani L2, Sobhani Z3, Haghighi ER4, Heydari M. (PubMed)
(2) Optimal Treatment of Symptomatic Hemorrhoids by Seok-Gyu Song and Soung-Ho Kim. (PMC)

#Lyophilized Stem Juice of #Banana Processes a Strong Hypoglycemic Effect on #Diabetes, According to Studies

Kyle J. Norton

Unripe banana may be considered a functional for the prevention and treatment of diabetes, some scientists suggested.

Diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate glucose as the result of either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

In some cases, diabetes is also caused by allergic reactions of cells in the immune system or immune
system mistakenly attacks the cells which produce insulin, leading to insulin resistance.

The death of beta cells in the pancreas is triggered by the massive overproduction of short strands of ribonucleic acid, known as microRNA (miR) 200. These results suggested that blocking miR-200 may guarantee the survival of beta cells, even ones under extreme stress.

In the case of the pancreas clogged up with fat accumulation, some researchers found that losing less than one gram of that fat through weight loss reverses diabetes.

Professor Taylor of Newcastle University said, “So if you ask how much weight you need to lose to make your diabetes go away, the answer is one gram! But that gram needs to be far from the pancreas. At present, the only way we have to achieve this is by calorie restriction by any means – whether by diet or an operation.

”In patients who had started with Type 2 diabetes, fat levels in the pancreas (pancreatic triglyceride) decreased by 1.2% over the 8 weeks. Very exact methods were needed to be able to measure this and a new method using a special MRI scan was developed. With an average pancreas for a person with Type 2 diabetes having a volume of 50 ml, this is the equivalent of around 0.6 grams of fat.

According to the study by ETH Zurich and the International Diabetes Foundation, there are over 380 million diabetics around the world. Approximately, by the year 2030, over half a billion people will be suffering from type 2 diabetes.

Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belonging to the family of the lily and the orchid.

In the study reaffirming the traditional use of bananas for the treatment of diabetes in India, researchers at the University College of Medical Sciences, Dilshad Garden launched an investigation to assess the antidiabetic and antihyperlipidemic effects of the stem of the banana. In the experiment, diabetes was induced in rats by streptozotocin injection (45 mg/kg, i.p.). Diabetic rats were treated for 2 weeks with different doses of lyophilized stem juice of banana. (25, 50, and 100 mg/kg) to select the most effective dose.

* The most effective dose of lyophilized stem juice of M. sapientum Linn (Banana) was 50 mg/kg.

* The four weeks treatment with this dose resulted in significant decreases in fasting and postprandial plasma glucose (FPG, PPG) levels.

* Serum insulin increased (P < 0.05) whereas HbA1c decreased (P < 0.05).

* Diabetes-induced changes to the lipid profile, muscle and liver glycogen, and enzyme activity (i.e. glucokinase, glucose-6-phosphatase, and HMG-CoA reductase) were restored near to normal levels by the application of banana.

These results suggested that lyophilized stem juice of banana (M. sapientum Linn) exhibits antidiabetic and antihyperlipidemic effects.

Furthermore, in the study to find out the mechanism of the hypoglycemic effect of ethanol extract of banana pseudostem (EE) researchers suggested
* The ethanol extract of banana significantly inhibited mammalian intestinal α-glucosidases and yeast α-glucosidase.

* Oral administration (100-200 mg kg(-1) body weight) of EE significantly suppressed the maltose/glucose-induced postprandial plasma glucose elevation and wielded an antihyperglycaemic effect in normal and alloxan-induced diabetic rats.

Dr. Ramu R, the lead scientist said, "EE might exert an anti-diabetic effect by inhibition of α-glucosidases from the intestine, in turn suppressing the carbohydrate absorption into the bloodstream. Hence the results extend a foundation for the future prospects of the food-derived enzyme inhibitors in the treatment of diabetes".

Additionally, according to the Central Food Technological Research Institute, banana flower and pseudostem have a low glycemic index and a high content of dietary fiber and antioxidants.

Application of the flower and pseudostem showed to inhibit diabetic symptoms like hyperglycemia, polyuria, polyphagia, polydipsia, urine sugar, and body weight in the rat model.

Taken all together, an unripe banana may be used as a functional food for the prevention and combined with primary therapy for the treatment of diabetes in humans, depending on the confirmation of further data collection from the large example size and multi-center studies.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Antidiabetic and antihyperlipidemic effects of the stem of Musasapientum Linn. in streptozotocin-induced diabetic rats by Dikshit P1, Shukla K, Tyagi MK, Garg P, Gambhir JK, Shukla R.(PubMed)
(2) Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats by Ramu R1, Shirahatti PS, Zameer F, Nagendra Prasad MN. (PubMed).
(3) Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats by Bhaskar JJ1, Shobha MS, Sambaiah K, Salimath PV. (PubMed)
(4) The life and death of beta cells by ETH Zurich
(5) Type 2 diabetes reversed by losing fat from pancreas by New Castle University

#Healthyfood #KaleJuices Reduces the Risk of Coronary Artery Disease by Lowering the Levels of Blood Cholesterols, Researchers Say

Kyle J. Norton

Cardiovascular diseases are a class of conditions associated with heart and blood vessels. Anything that affects the normal heart and blood vessel functioning is considered risk factors of the diseases, including the heart's muscle, valves or rhythm, and blockage of blood vessels.

According to the statistics, in the US, approximately, 610,000 people die of heart disease every year that's 1 in every 4 deaths. The disease is the leading cause of death for both men and women.

The causes of cardiovascular diseases are associated with the location that affects the functioning of the heart and blood vessels, including atherosclerosis caused by the blockade of the blood vessel due to the accumulation of plaques in the arteries and arrhythmias caused by abnormal heart rhythms.

Coronary artery disease is a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial walls, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc.

The disease has been found to affect the small blood vessels that supply blood and oxygen to the heart.

Coronary artery disease (CHD) is the leading cause of death in the United States.
According to statistics, coronary artery disease is the most common type of heart disease that causes the death of over 370,000 people every year, representing 28% of all death in the United States.

Sadly, according to the Centers for Disease Control and Prevention, approximately, 735,000 Americans have a heart attack each year.

What causes plaques to build up on the arterial is debatable. However, researchers suggested that the Western diet is associated with a significantly increased risk of coronary artery disease.

Kale is a species of Brassica Oleracea, belonging to the family Brassicaceae, native to coastal southern and western Europe. Since kale leave is highly nutritious and easy to grow with a range of long seasons from the middle of winter through the beginning of spring, it is cultivated as food in most parts of Europe.

In finding a potential whole for the treatment of cardiovascular diseases, researchers evaluated the effect of 3-month kale (Brassica oleracea acephala) juice supplementation on coronary artery disease.

The study included 32 men with hypercholesterolemia (> 200 mg/dL) recruited after annual health examinations among the faculty and staff at the university and consumed 150 mL of kale juice per day for a 12-week intervention period.

Based on the blood samples used to evaluate biochemical profiles before and after supplementation, researchers found that
* Serum concentrations of HDL-cholesterol, and HDL- to LDL-cholesterol ratio were significantly increased by 27% and 52%, respectively.

* The LDL-cholesterol concentration and the atherogenic index were significantly reduced by 10% (P=0.0007) and 24.2% (P<0.0001), respectively without affecting body mass index, waist and hip circumferences, or nutrient intakes after three months of supplementation.

Based on the findings, researchers said, "Regular meals supplementation with kale juice can favorably influence serum lipid profiles and antioxidant systems, and hence contribute to reducing the risks of coronary artery disease in male subjects with hyperlipidemia".

Taken together, kale may be considered a functional food for the prevention and treatment of coronary artery disease in patients with hyperlipidemia, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Kale juice improves coronary artery disease risk factors in hypercholesterolemic men by Kim SY1, Yoon S, Kwon SM, Park KS, Lee-Kim YC. (PubMed)

#Field Mustard Kills #LungCancer Cells by inducing Cell Cycle Arrest and Apoptosis and Suppressjng Migration, According to Studies

Kyle J. Norton

Cancer is a class of diseases caused by cell growth and multiplication disorderly and uncontrollably due to the alternation of the DNA.

After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.

The most advanced stage of cancer may result in the death of the patient.

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions that inhale oxygen from the air and then transport them to the bloodstream to nourish the body cells' needs and to exhale carbon dioxide from the bloodstream.

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells.

The exact cause of lung cancer is not identified. However, epidemiologically, smoking, second smoke, exposure to certain chemicals, family history, people who have lung disease, and excessive drinking are some prevalent factors associated with lung cancer developing.


Current and past smoking account for most cases of lung cancer. The risk of developing lung cancer is about 23 times higher in male smokers compared to non-smokers, epidemiologically.

The most common glands and organs of lung cancer metastases are adrenal glands, bones, brain, and liver.

According to the statistics provided by the American cancer society, lung cancer accounts for 14% of all new cancers diagnosed in the US. In 2018, there were about 234,030 new cases of lung cancer (121,680 in men and 112,350 in women). Lung cancer also causes the death of 83,550 in men and 70,500 in women in the same year.

In finding a potential plant that processes anti-invasive tumor activity researchers compared the effects of an n-butanol subfraction of B. Rapa L. (BRBS) anti-tumor effect on A549 lung adenocarcinoma cell.

According to the experimental results,
* BRBS treatment in a dose- and time-dependent manner, significantly inhibited the proliferation of A549 cells.

* Furthermore, by activating the increased reactive oxygen species (ROS) production to induce cytotoxic effects, BRBS significantly induced cell cycle arrest and apoptosis in A549 cells.

* Moreover, the inhibition was also found to exhibit cancer cell mitochondrial dysfunction characterized by a reduction in mitochondrial membrane potential and the release of cytochrome c, which promoted caspase-3 and poly(ADP-ribose) polymerase processing.

* Additionally, BRBS significantly suppressed the migration of A549 cells in vitro.

Collectively, scientists wrote, "BRBS inhibited A549 cell proliferation through increased ROS production and the mitochondria-dependent apoptosis pathway. Consequently, BRBS might be a potential candidate for the treatment of lung cancer".

Taken together, field mustard may be considered a functional food for the prevention and treatment of lung cancer, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway by Aipire A1, Chen Q2, Cai S3, Li J4, Fu C5, Ying T6, Lu J7, Li J. (PubMed)

#Potato Exerts A Significant Effect on #OralHealth Against Oral Bacterial Strains, Researchers Find

Kyle J. Norton

Infectious diseases are a class of conditions caused by the invasion of pathogenic microorganisms, such as bacteria, viruses, parasites, or fungi.

Bacteria is a type of biological cell consisting of a single cell with a simple internal structure.

Out of millions of bacteria present in this world, only a hundred of them cause infectious diseases. And, most bacteria that cause large-scale diseases in human history may be close to extinction.

In contrast to general belief, most bacteria live as independent cells, they share the basic characteristics of all living things, they breathe, metabolize, produce waste, and maintain a membrane potential.

However, bacteria do not process a nucleus in which their DNA is separated from the rest of the cell.

In the differentiation of bacteria, one must know that not all bacteria are bad. Some bacteria found in the digestive tract have been found to aid digestion and prevent the imbalance of bad and good bacteria. In other words, most bacteria are harmless.

The most common diseases caused by bacteria include strep throat, urinary tract infections, and tuberculosis.

Infection occurs when the bacteria successfully invade the body and start to multiply. Most cases of infectious diseases caused by bacteria are treated with antibiotics.

And, most cases of infectious disease are transmitted by airborne you can get sick if you breathe into the air that carries infectious bacteria in air particles, vector-borne if you are stunk by the insect that the bacteria, and vehicle-borne if you are eating food or carrying the materials contaminated by the bacteria.

Potato is the genus Solanum, belongs to the family Solanaceae. It is a good source of protein and according to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. It now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.

On finding a potential plant that processes anti-infectious properties, researchers evaluated the antibacterial and cytotoxic activity of a new experimental tooth based on Solanum tuberosum "Tocosh" on the cell lines 3T3 and DU145.

According to the tested analysis
* Solanum tuberosum (toosh) was not cytotoxic because it only had one CC50 at the concentration of 0.26927 mg/mL and 0.26845 mg/mL for cell lines 3T3 and DU145, respectively.

* However, tocosh toothpaste (TD) has an antibacterial effect against S. aureus and S. mutans.

In other words, Solanum tuberosum showed no effects to induce cell death in the tested cancer cell lines but exerted a strong activity against certain oral bacterial strains.

Collectively, researchers said, "This research has great potential for clinical use because this new dentifrice has antimicrobial activity against different oral germs".

Taken altogether, potatoes may be considered a functional food for the prevention and treatment of infectious diseases, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity by Mayta-Tovalino F1, Sedano-Balbin G2, Romero-Tapia P2, Alvítez-Temoche D3, Álvarez-Paucar M4, Gálvez-Calla L5, Sacsaquispe-Contreras S. (PubMed)

#Herbal #shwagandha Enhances the Fertility Rate in Normozoospermic Men, Researchers Say

Kyle J. Norton

Fertility is a natural process to ensure the survival of human species. Through natural selection, we produce many offsprings when the reproductive system works at its peak in a suitable environment.

In other words, female fertility is the ability of women to conceive a biological child before menopause compared to male fertility which generally relies on the quantity and quality of the sperm.

But regardless of all factors, most women are capable of conceiving during their menstrual cycle before reaching the stage of menopause.

Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to term.

The condition affects over 5 million couples alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seek help from a professional specialist.

Male infertility is a medical condition associated with the male's inability to cause pregnancy in a fertile female.

Male infertility accounts for 40–50% of all cases of infertility, affecting over 7% of all men.
Most cases of male infertility are the results of deficiencies in the semen, and semen quality that lead to reduced function of male fecundity.

The exact causes of male infertility are not identified. However, abnormal sperm production or function due to genetic defects, and medical conditions such as diabetes, or infectious diseases such as chlamydia, gonorrhea, mumps are some of the prevalent factors that are involved in the increased risk of male infertility.

Believe it or not, stress caused by a number of health problems, including heart disease, asthma, obesity, and depression may lead to reduce sperm and semen quality in male fertility.

Dr. Nargund VH said, "Psychological stress can be defined as any uncomfortable 'emotional experience' accompanied by predictable biochemical, physiological and behavioral changes or responses. Many clinical studies looking at the effects of psychological stress on male fertility have shown that stress is associated with reduced paternity and abnormal semen parameters".

And, "psychological stress could severely affect spermatogenesis, mainly as a result of varying testosterone secretion. The hypothalamic-pituitary-adrenal axis has a direct inhibitory action on the hypothalamic-pituitary-gonadal (HPG) axis and Leydig cells in the testes. The newly discovered hormone, gonadotropin-inhibitory hormone (GnIH), also has an inhibitory effect on the HPG axis. Inhibition of the HPG axis results in a fall in testosterone levels, which causes changes in Sertoli cells and the blood-testis barrier, leading to the arrest of spermatogenesis".

Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

In finding a potential compound for the improvement of male fertility, researchers examined the efficacy and safety of W. somnifera treatment in infertile men.

The evidence-based systematic review and meta-analysis were conducted by searching the database of medical literature PubMed/MEDLINE, EMBASE, Scopus, the Cochrane Library, and DHARA. Grey literature was assessed from the WHO International Clinical Trials Registry Platform (http://apps.who.int/trialsearch/) and the US National Institutes of Health (https://clinicaltrials.gov/).

According to the 4 clinical trials (comprising 5 publications: observational, n = 4; randomized controlled trial [RCT], n = 1), only one RCT were included in the analysis, W. somnifera treatment significantly improved semen parameters including semen volume: mean difference [MD], 0.28  ml; sperm concentration: MD, 13.57 million/ml; sperm motility: MD, 8.50%

Furthermore, W. somnifera administration also improves the fertility rate in normozoospermic men by 14%


Moreover, according to the results of the meta-analysis, W. somnifera treatment also exerted a significant improvement in serum hormonal profile, oxidative biomarkers, and antioxidant vitamins in seminal plasma.

No adverse effects were reported during the study.

In other words, W. somnifera enhances all parameters associated with sperm integrity and viability in the promotion of conception without inducing any side effects.

Based on the findings, researchers after taking other factors into account wrote, "Due to a small number of eligible studies, the available data, though promising, are too limited to provide novel and sufficiently robust evidence of the benefits of W. somnifera in male infertility. Additional RCTs of high quality with a larger sample size are warranted to further strengthen clinical use of W. somnifera in treating male factor infertility".

Taken together, Ashwagandha may be considered a remedy for the treatment of male infertility, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Role of Withania somnifera (Ashwagandha) in the management of male infertility by Sengupta P1, Agarwal A2, Pogrebetskaya M3, Roychoudhury S4, Durairajanayagam D5, Henkel R. (PubMed)
(2) Withania somnifera (Indian ginseng) in male infertility: An evidence-based systematic review and meta-analysis by Durg S1, Shivaram SB2, Bavage S. (PubMed)
(3) Effects of psychological stress on male fertility by Nargund VH. (PubMed)

#Isonitrogenous and Isocaloric Diets Supplemented with #Artichoke Bracts (AB) Promote Healthy Levels of Free Fatty Acids, Researchers Find

Kyle J. Norton

Free fatty acids found in fats and oils and in cell membranes are the by-products produced in the metabolism of fat in adipose tissues.

In other words, free fatty acids are produced by breaking down fats into fatty acids, which can then be absorbed into the blood.

Fatty acids can be used as fuel for the cells if glucose is not available for energy.

Free fatty acids play a critical role in the maintenance of our body functioning, including
* Cell signaling through the formation of eicosanoids, a group of signaling molecules involved in the immune response.

* In metabolism, FFAs play essential roles in the regulation of energy metabolism and mediation of a wide range of metabolic processes.

* In cells, FFAs are used for the formation of cell membranes or walls.

* More importantly, FFAs also have a strong effect on endothelial function and dysfunction.

Dr. Carmen Gonzalez, the lead scientist in the examination of the role of free fatty acids wrote, "FFARs have been targeted in drug development for the treatment of type 2 diabetes and metabolic syndrome. FFAs upregulate transcription of uncoupling proteins, increasing their expression in brain, cardiac, and skeletal muscle that may be protective or cytotoxic, depending on the cellular energy state".

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belongings to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

With an aim to find a natural ingredient for the improvement of healthy levels of free fatty acids (FFAs) in humans, researchers examined the artichoke bracts (AB) in an animal model.

The study included a total of 120 rabbits aged 38 days divided into three groups fed with different isonitrogenous and isocaloric diets supplemented with AB at 0%, 5%, and 10%.

At 96 days of age, after observing the carcasses of 12 rabbits slaughtered in an experimental slaughterhouse without fasting, researchers found that the levels of α-linolenic acid proportion were decreased with the injection of AB supplementation from 3.58% to 2.59% in the LD muscle and from 4.74% to 3.62% in the perirenal fat.

Furthermore, the meat ether extract (FFAs) content also was increased from 0.68% to 0.94% on a fresh matter basis by the injection of AB supplementation.

The levels of n-6/n-3 ratio increased significantly with increasing AB inclusion from 7.15 to 10.20 in the LD muscle and from 6.68 to 9.35 in the perirenal fat.

The results suggested that artichoke has a strong impact on improving quality and fatty acid composition.

Moreover, in order to reveal additional information about artichoke on fatty acids, researchers launched an investigation of Nigella sativa, lupin, and artichoke seed oils' fatty acids (FA, as methyl esters) using gas chromatographic analysis (GLC).

At the end of the experiment, researchers found that three seed oils are rich in FFAs including oleic and linoleic acid content.

According to the results from the high-pressure liquid chromatography (HPLC) assay, artichoke oil was unique in having a high content of 5-stigma-, 7-stigma-, and avenasterol compared to those of Nigella sativa, Lupin, particularly in levels of FSG and ASG.

The findings lead us to say that artichoke seed oil can be recommended as a healthy oil and folk medicine, according to Dr. M Hassanein MM, the lead scientist at the National Research Centre, Fats, and Oils Dept, Egypt.

Taken altogether, artichoke (seed oils) may be considered a healthy choice of free fatty acids for reducing the risk of diseases associated with high blood pressure, insulin resistance, high triglycerides, and low “good” HDL cholesterol levels, pending the validation of larger sample size and multicenter human study


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Dried artichoke bracts in rabbits nutrition: effects on the carcass characteristics, meat quality and fatty-acid composition by Dabbou S1, Gasco L1, Gai F2, Zoccarato I1, Rotolo L1, Dabbou Fekih S3, Brugiapaglia A1, Helal AN3, Peiretti PG. (PubMed)
(2) Investigation of lipids profiles of Nigella, lupin and artichoke seed oils to be used as healthy oils by M Hassanein MM1, El-Shami SM, El-Mallah MH. (PubMed)
(3) Role of Free Fatty Acids in Physiological Conditions and Mitochondrial Dysfunction by Zbigniew K. Binienda, Sumit Sarkar, Sonia Silva-Ramirez, Carmen Gonzalez. (Scientific Research)