Kyle J. Norton
Fat including cholesterol and triglycerides consists of hydrocarbon molecules.
Dyslipidemia is a condition of abnormal levels of lipids in their blood.
Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.
Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.
Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones, and bile acid to aid digestion in the small intestine.
Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).
The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.
On the other hand, triglyceride is fat in the blood that comes from an outside source used by the body to convert to energy.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
Triglyceride is stored in the fat cells used to produced energy between meals and in the case when food is scarce.
Compared to cholesterol, triglycerides in high levels are also associated with the risk of heart disease, particularly in people with high levels of LDL and low levels of HDL.
In finding a potential phytochemical for the treatment of diseases associated with high blood cholesterol, researchers examined the Omega 3 fatty acid activity in the management of hypertriglyceridemia.
According to the results of the study,
* Omega 3 fatty acids lowered LDL cholesterol and reduce CV risk.
* Omega 3 fatty acid also lowered triglyceride (TG) levels and elevated the high-density lipoprotein (HDL) cholesterol levels.
* Omega3 fatty acid inhibited the elevated TG levels that increased the risk of CV events and very high TG levels are associated with acute pancreatitis.
Collectively, researchers said, " This review focuses on the clinical practice guidelines for the management of hypertriglyceridemia and the role of prescription omega-3 fatty acids in preventing pancreatitis and CV disease in individuals with high and very high TG levels".
Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of dyslipidemia, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(2) A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids by Karalis DG. (PubMed)
Wednesday, 12 July 2023
#Lycopene Exerts #Chemoprevention, Such as Induced Apoptosis and Antiproliferation and Anti-Metastasis in Cancer, Researchers Say
Kyle J. Norton
Cancer is a class of diseases associated with cell growth disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of organs or glands. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Multitargeted therapy of cancer treatment, in general, induces an imbalance between cell survival and apoptosis through interference by enhancing the cell cycle regulators and proteins involved in apoptosis.
Dr. Mehta K, the lead scientist in the joint study led by The University of Texas MD Anderson Cancer Center, wrote, "The Society of Translational Cancer Research held its biennial meeting in the capital city of India, Delhi from February 6th through 9th, 2014 to discuss 'Multi-targeted Approach to Treatment of Cancer"
And "Talks were presented by leaders in the cancer research field from various countries. It became clear from this conference that coupling multiple targeted agents or using an agent that hits an individual target in several independent locations in the disease-causing pathway(s) may be the best approach to treat different cancers".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of cancer, researchers examined the role of lycopene (L) as a multi-targeted therapy for cancer.
In vitro, lycopene exerted many mechanisms of chemoprevention, including the induction of apoptosis and antiproliferation in cancer cells, and anti-metastatic activity.
Furthermore, lycopene also enhanced and promoted an antioxidant response in the synthesis of cytoprotective enzymes.
Moreover, lycopene, a substrate for carotene-9',10'-monooxygenase (CMO2) and can be converted to apo-10'-carotenal plays a critical to inhibit cancer cell migration and angiogenesis.
Taken altogether, lycopene found in tomatoes may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Multitargeted therapy of cancer by lycopene by van Breemen RB1, Pajkovic N. (PubMed)
(2) Multi-targeted approach to cancer treatment: an international translational cancer research symposium by Mehta K1, Gandhi V2, Pathak S3, Aggarwal BB2, Grover RK. (PubMed)
Cancer is a class of diseases associated with cell growth disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of organs or glands. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite, and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Multitargeted therapy of cancer treatment, in general, induces an imbalance between cell survival and apoptosis through interference by enhancing the cell cycle regulators and proteins involved in apoptosis.
Dr. Mehta K, the lead scientist in the joint study led by The University of Texas MD Anderson Cancer Center, wrote, "The Society of Translational Cancer Research held its biennial meeting in the capital city of India, Delhi from February 6th through 9th, 2014 to discuss 'Multi-targeted Approach to Treatment of Cancer"
And "Talks were presented by leaders in the cancer research field from various countries. It became clear from this conference that coupling multiple targeted agents or using an agent that hits an individual target in several independent locations in the disease-causing pathway(s) may be the best approach to treat different cancers".
Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a potential compound for the treatment of cancer, researchers examined the role of lycopene (L) as a multi-targeted therapy for cancer.
In vitro, lycopene exerted many mechanisms of chemoprevention, including the induction of apoptosis and antiproliferation in cancer cells, and anti-metastatic activity.
Furthermore, lycopene also enhanced and promoted an antioxidant response in the synthesis of cytoprotective enzymes.
Moreover, lycopene, a substrate for carotene-9',10'-monooxygenase (CMO2) and can be converted to apo-10'-carotenal plays a critical to inhibit cancer cell migration and angiogenesis.
Taken altogether, lycopene found in tomatoes may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Multitargeted therapy of cancer by lycopene by van Breemen RB1, Pajkovic N. (PubMed)
(2) Multi-targeted approach to cancer treatment: an international translational cancer research symposium by Mehta K1, Gandhi V2, Pathak S3, Aggarwal BB2, Grover RK. (PubMed)
#Cabbage Inhibits #EstrogenResponseMarker and Increased Cytotoxicity in #EndometrialCancer Cells in Vivo, Researchers Say
Kyle J. Norton
The endometrium is the inner lining of the mammalian uterus and is very susceptible to hormone change, particularly in the menstrual cycle.
Endometrial cancer is a chronic condition characterized by irregular cells in the tissue of the endometrium.
It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
Most cases of endometrial cancer start on the cells on the surface of the inner lining of the endometrium. At the advanced stage, after penetrating into the deeper layers, malignant cancer cells may travel a distance away to infect other healthy tissue and organs.
Endometrial cancer has been found to metastasize to the rectum, bladder, pelvic and para-aortic lymph nodes, and vagina.
The exact causes of endometrial cancer are unknown. Epidemiological studies suggested that the increase in age, more years of menstruation, never been pregnant, obesity, and the use of hormone therapy are some of the major prevalent risk factors associated with endometrial cancer.
Some researchers indicated that hormone changes in women's bodies such as higher androgen and estrogen levels and lower levels of progesterone due to polycystic.
In the US, endometrial cancer is the most common cancer of the female reproductive organs. Every year, approximately About 63,000 new cases of uterus cancer are diagnosed, causing the death of 11,000 women.
The 5-year survival rates for white and black women with the disease are 84% and 62% respectively.
At the invasive stage, the survival rate is 16%.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
In findings a natural whole for the treatment of cancer, researchers examined the effects of 3,3'-Diindolylmethane (DIM), a major in vivo product of indole-3-carbinol (I3C), which is a promising anticancer agent derived from vegetables of the Brassica genus including cabbage on the endometrial cancer cell line.
According to the results of the tested analysis,* DIM induced cytotoxic activity by increasing the level of TGF-alpha transcripts by approximately 4-fold within 24 h of indole treatment in the tested cancer cells.
* DIM also induced a 4-fold increase in the activity of the estrogen response marker, alkaline phosphatase (AP), the cancer markers.
In other words, DIM increased the maximum stimulatory effect of estrogen on TGF-alpha expression to induce cancer cell death.
* DIM alone treatment stimulated levels of secreted TGF-alpha protein by >10-fold. More precisely, the elevated addition of TGF-alpha inhibited the growth of Ishikawa cells, whereas incubation with a TGF-alpha antibody partially reversed the growth inhibitory effects of DIM.
Based on the results, researchers wrote, " ligand-independent estrogen receptor agonist activity of DIM, and uncover an essential role for the stimulation in TGF-alpha expression and the TGF-alpha activated signal transduction pathway in the potent cytostatic effects of DIM in endometrial cancer cells".
Taken altogether, cabbage may be considered a functional food for the treatment of endometrial cancer pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression by Leong H1, Firestone GL, Bjeldanes LF. (PubMed)
The endometrium is the inner lining of the mammalian uterus and is very susceptible to hormone change, particularly in the menstrual cycle.
Endometrial cancer is a chronic condition characterized by irregular cells in the tissue of the endometrium.
It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
Most cases of endometrial cancer start on the cells on the surface of the inner lining of the endometrium. At the advanced stage, after penetrating into the deeper layers, malignant cancer cells may travel a distance away to infect other healthy tissue and organs.
Endometrial cancer has been found to metastasize to the rectum, bladder, pelvic and para-aortic lymph nodes, and vagina.
The exact causes of endometrial cancer are unknown. Epidemiological studies suggested that the increase in age, more years of menstruation, never been pregnant, obesity, and the use of hormone therapy are some of the major prevalent risk factors associated with endometrial cancer.
Some researchers indicated that hormone changes in women's bodies such as higher androgen and estrogen levels and lower levels of progesterone due to polycystic.
In the US, endometrial cancer is the most common cancer of the female reproductive organs. Every year, approximately About 63,000 new cases of uterus cancer are diagnosed, causing the death of 11,000 women.
The 5-year survival rates for white and black women with the disease are 84% and 62% respectively.
At the invasive stage, the survival rate is 16%.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
In findings a natural whole for the treatment of cancer, researchers examined the effects of 3,3'-Diindolylmethane (DIM), a major in vivo product of indole-3-carbinol (I3C), which is a promising anticancer agent derived from vegetables of the Brassica genus including cabbage on the endometrial cancer cell line.
According to the results of the tested analysis,* DIM induced cytotoxic activity by increasing the level of TGF-alpha transcripts by approximately 4-fold within 24 h of indole treatment in the tested cancer cells.
* DIM also induced a 4-fold increase in the activity of the estrogen response marker, alkaline phosphatase (AP), the cancer markers.
In other words, DIM increased the maximum stimulatory effect of estrogen on TGF-alpha expression to induce cancer cell death.
* DIM alone treatment stimulated levels of secreted TGF-alpha protein by >10-fold. More precisely, the elevated addition of TGF-alpha inhibited the growth of Ishikawa cells, whereas incubation with a TGF-alpha antibody partially reversed the growth inhibitory effects of DIM.
Based on the results, researchers wrote, " ligand-independent estrogen receptor agonist activity of DIM, and uncover an essential role for the stimulation in TGF-alpha expression and the TGF-alpha activated signal transduction pathway in the potent cytostatic effects of DIM in endometrial cancer cells".
Taken altogether, cabbage may be considered a functional food for the treatment of endometrial cancer pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression by Leong H1, Firestone GL, Bjeldanes LF. (PubMed)
#Omega-3 Fatty Acids Inhibit #GastrointestinalCancer through Their #Antioxidant and #AntiInflammatory Activities, Researchers Say
Kyle J. Norton
Cancer is a class of diseases in which a group of cells grow and multiply disorderly and uncontrollably in our body.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
The digestive system including the gastrointestinal tract, the liver, pancreas, and gallbladder play a critical role to maintain the body's normal function by providing nutrients and fluids to the body and remove waste through the secretary system.
The gastrointestinal tract formed part of the digestive system is a series of hollow organs that form a long continuous passage from our mouth to our anus, including our mouth, esophagus, stomach, small intestine, large intestine, and anus.
Gastrointestinal cancer is a medical and chronic condition caused by the alternation of cell DNA in the gastrointestinal tract including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum, and anus.
The most common gastrointestinal cancer is gastric cancer, which is the fourth most commonly occurring cancer in men and the seventh most commonly occurring cancer in women.
According to worldwide statistics, over 1 million new cases were diagnosed in 2018 with the South Korean leading the map, second to Mongolia.
In other words, if you are Asian, you are at an increased risk of gastric cancer.
At the advanced stage, the cancer cell of the affected tissues can travel a distance away to infect the other tissues and organs, leading to secondary metastasis.
Epidemiologically, primary gastrointestinal cancer is more likely to spread to the stomach, esophageal cancer, breast cancer, renal cell carcinoma, and ovarian cancer.
The exact causes of gastrointestinal cancer are not identified. However, genetic preposition, unhealthy lifestyle, and medical conditions are some of the prevalent risks of the disease.
Some researchers suggested that a poor diet may have a strong implication on the incidence of gastrointestinal cancer.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of digestive diseases, researchers examined the effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on gastrointestinal (GI) cancer.
* n-3 PUFAs may exert their anticancer actions by influencing multiple targets implicated in various stages of cancer development.
* n-3 PUFAs especially imposed excellent actions of antiinflammation and antioxidation, as well as their restorative actions against gastrointestinal cancer developing by restoring or modifying the inflammation-associated lipid distortion and alteration of lipid rafts.
* However, the study of the effects of n-3 PUFAs against GI cancer is still limited.
Taken together, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of GI cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 polyunsaturated Fatty acids as a potential chemopreventive agent for gastrointestinal cancer by Park JM1, Kwon SH1, Han YM2, Hahm KB3, Kim EH. (PubMed)
(2) Potential applications of fish oils rich in omega-3 polyunsaturated fatty acids in the management of gastrointestinal cancer by Eltweri AM1, Thomas AL2, Metcalfe M3, Calder PC4, Dennison AR3, Bowrey DJ. (PubMed)
Cancer is a class of diseases in which a group of cells grow and multiply disorderly and uncontrollably in our body.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
The digestive system including the gastrointestinal tract, the liver, pancreas, and gallbladder play a critical role to maintain the body's normal function by providing nutrients and fluids to the body and remove waste through the secretary system.
The gastrointestinal tract formed part of the digestive system is a series of hollow organs that form a long continuous passage from our mouth to our anus, including our mouth, esophagus, stomach, small intestine, large intestine, and anus.
Gastrointestinal cancer is a medical and chronic condition caused by the alternation of cell DNA in the gastrointestinal tract including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum, and anus.
The most common gastrointestinal cancer is gastric cancer, which is the fourth most commonly occurring cancer in men and the seventh most commonly occurring cancer in women.
According to worldwide statistics, over 1 million new cases were diagnosed in 2018 with the South Korean leading the map, second to Mongolia.
In other words, if you are Asian, you are at an increased risk of gastric cancer.
At the advanced stage, the cancer cell of the affected tissues can travel a distance away to infect the other tissues and organs, leading to secondary metastasis.
Epidemiologically, primary gastrointestinal cancer is more likely to spread to the stomach, esophageal cancer, breast cancer, renal cell carcinoma, and ovarian cancer.
The exact causes of gastrointestinal cancer are not identified. However, genetic preposition, unhealthy lifestyle, and medical conditions are some of the prevalent risks of the disease.
Some researchers suggested that a poor diet may have a strong implication on the incidence of gastrointestinal cancer.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of digestive diseases, researchers examined the effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on gastrointestinal (GI) cancer.
* n-3 PUFAs may exert their anticancer actions by influencing multiple targets implicated in various stages of cancer development.
* n-3 PUFAs especially imposed excellent actions of antiinflammation and antioxidation, as well as their restorative actions against gastrointestinal cancer developing by restoring or modifying the inflammation-associated lipid distortion and alteration of lipid rafts.
* However, the study of the effects of n-3 PUFAs against GI cancer is still limited.
Taken together, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of GI cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 polyunsaturated Fatty acids as a potential chemopreventive agent for gastrointestinal cancer by Park JM1, Kwon SH1, Han YM2, Hahm KB3, Kim EH. (PubMed)
(2) Potential applications of fish oils rich in omega-3 polyunsaturated fatty acids in the management of gastrointestinal cancer by Eltweri AM1, Thomas AL2, Metcalfe M3, Calder PC4, Dennison AR3, Bowrey DJ. (PubMed)
#Healthyfood #Honey Normalizes the Levels of Blood Cholesterol by Improving the Antioxidant Levels in the Blood, Researchers Find
Kyle J. Norton
Scientists may have found a natural alternative for the treatment of hyperlipidemia according to a study. Hyperlipidemia is a condition of high levels of cholesterol in the bloodstream. Cholesterol is a waxy substance that is needed for the body to build cell walls, aid digestion, and make steroid hormones and vitamin D.
Cholesterol can be produced by the liver or by eating some fatty foods. There are 2 types of cholesterol, the low-density lipoprotein (LDL) which carries the aforementioned functions, and the high-density lipoprotein (HDL) which returns the cholesterol to the liver for reuse.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lowers than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
Although there are many risk factors associated with the onset of hyperlipidemia, some researchers suggested that the association between widespread obesity and hyperlipidemia in US adults is worrisome in the scientific community.
Dr. Boudewijn Klop and their colleagues at the Diabetes and Vascular Centre, Sint Franciscus Gasthuis wrote, "Obesity increases cardiovascular risk through risk factors such as increased fasting plasma triglycerides, high LDL cholesterol, low HDL cholesterol, elevated blood glucose, and insulin levels and high blood pressure. Novel lipid-dependent, metabolic risk factors associated with obesity are the presence of the small dense LDL phenotype, postprandial hyperlipidemia with an accumulation of atherogenic remnants, and hepatic overproduction of apoB-containing lipoproteins".
And, "All these lipid abnormalities are typical features of the metabolic syndrome and may be associated with a pro-inflammatory gradient which in part may originate in the adipose tissue itself and directly affect the endothelium".
The results strongly suggested the association between obesity and the onset of abnormal blood cholesterol contributes to many complications and diseases.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener.
Scientists on finding a natural compound for the treatment of cholesterol examined honey's effects on patients with high cholesterol concentrations.
The study included 60 volunteers with high cholesterol, stratified according to gender and hydroxymethyl-glutaryl-coenzyme A reductase inhibitor (statin) treatment (yes/no), randomized to receive 75 g of the honey solution or a honey-comparable sugar solution once daily over a period of 14 days.
Measurements repeated 2 weeks later, showed that BMI and high-density lipoprotein (HDL) cholesterol values were significantly correlated (r = -0.487; P < .001) as were BMI and a lower ratio of low-density lipoprotein (LDL) cholesterol to HDL cholesterol (r = 0.420; P < .001).
In other words, with the injection of honey, subjects with a high BMI had a lower HDL cholesterol value.
Even though neither solution influenced significantly cholesterol or triglyceride values in the total group; substituting honey for sugar in their diet showed to reduce the BMI and lower the LDL cholesterol value.
The finding suggested honey does not have a direct effect on normalizing the levels of blood cholesterol but indirectly reduces the patient's BMI value, which has been found to have strong effects in decreasing the levels of cholesterol.
Furthermore, according to research presented at the national meeting of the American Chemical Society, the world's largest scientific society, honey fights cholesterol as well as some fruits and vegetables.
The study included 25 men between the ages of 18 - and 68 who are given a mixture of water and honey, about four tablespoons per 16-ounce glass in a five-week.
A blood sample withdrawn at the end of the experience showed reduced levels of cholesterol by improving the antioxidant levels in the blood.
Moreover, the application of the mixture also has a significant effect in reducing the risk of atherosclerosis caused by plaque such as cholesterol and other substances build up on the arterial wall.
The onset of atherosclerosis is a major cause of heart disease in the US.
The results suggested that replacing the use of sweetening agents, like sugar with honey may improve the antioxidant status in reducing the risk of cholesterol overexpression in the bloodstream.
Taken altogether, honey may be considered a functional remedy for the prevention and treatment of high blood cholesterol, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on serum cholesterol and lipid values by Münstedt K1, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. (PubMed)
(2) Honey Fights Cholesterol As Well As Some Fruits And Vegetables by American Chemical Society. (Science Daily)
(3) Dyslipidemia in Obesity: Mechanisms and Potential Targets by Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas. (PMC)
Scientists may have found a natural alternative for the treatment of hyperlipidemia according to a study. Hyperlipidemia is a condition of high levels of cholesterol in the bloodstream. Cholesterol is a waxy substance that is needed for the body to build cell walls, aid digestion, and make steroid hormones and vitamin D.
Cholesterol can be produced by the liver or by eating some fatty foods. There are 2 types of cholesterol, the low-density lipoprotein (LDL) which carries the aforementioned functions, and the high-density lipoprotein (HDL) which returns the cholesterol to the liver for reuse.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lowers than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
Although there are many risk factors associated with the onset of hyperlipidemia, some researchers suggested that the association between widespread obesity and hyperlipidemia in US adults is worrisome in the scientific community.
Dr. Boudewijn Klop and their colleagues at the Diabetes and Vascular Centre, Sint Franciscus Gasthuis wrote, "Obesity increases cardiovascular risk through risk factors such as increased fasting plasma triglycerides, high LDL cholesterol, low HDL cholesterol, elevated blood glucose, and insulin levels and high blood pressure. Novel lipid-dependent, metabolic risk factors associated with obesity are the presence of the small dense LDL phenotype, postprandial hyperlipidemia with an accumulation of atherogenic remnants, and hepatic overproduction of apoB-containing lipoproteins".
And, "All these lipid abnormalities are typical features of the metabolic syndrome and may be associated with a pro-inflammatory gradient which in part may originate in the adipose tissue itself and directly affect the endothelium".
The results strongly suggested the association between obesity and the onset of abnormal blood cholesterol contributes to many complications and diseases.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener.
Scientists on finding a natural compound for the treatment of cholesterol examined honey's effects on patients with high cholesterol concentrations.
The study included 60 volunteers with high cholesterol, stratified according to gender and hydroxymethyl-glutaryl-coenzyme A reductase inhibitor (statin) treatment (yes/no), randomized to receive 75 g of the honey solution or a honey-comparable sugar solution once daily over a period of 14 days.
Measurements repeated 2 weeks later, showed that BMI and high-density lipoprotein (HDL) cholesterol values were significantly correlated (r = -0.487; P < .001) as were BMI and a lower ratio of low-density lipoprotein (LDL) cholesterol to HDL cholesterol (r = 0.420; P < .001).
In other words, with the injection of honey, subjects with a high BMI had a lower HDL cholesterol value.
Even though neither solution influenced significantly cholesterol or triglyceride values in the total group; substituting honey for sugar in their diet showed to reduce the BMI and lower the LDL cholesterol value.
The finding suggested honey does not have a direct effect on normalizing the levels of blood cholesterol but indirectly reduces the patient's BMI value, which has been found to have strong effects in decreasing the levels of cholesterol.
Furthermore, according to research presented at the national meeting of the American Chemical Society, the world's largest scientific society, honey fights cholesterol as well as some fruits and vegetables.
The study included 25 men between the ages of 18 - and 68 who are given a mixture of water and honey, about four tablespoons per 16-ounce glass in a five-week.
A blood sample withdrawn at the end of the experience showed reduced levels of cholesterol by improving the antioxidant levels in the blood.
Moreover, the application of the mixture also has a significant effect in reducing the risk of atherosclerosis caused by plaque such as cholesterol and other substances build up on the arterial wall.
The onset of atherosclerosis is a major cause of heart disease in the US.
The results suggested that replacing the use of sweetening agents, like sugar with honey may improve the antioxidant status in reducing the risk of cholesterol overexpression in the bloodstream.
Taken altogether, honey may be considered a functional remedy for the prevention and treatment of high blood cholesterol, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on serum cholesterol and lipid values by Münstedt K1, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. (PubMed)
(2) Honey Fights Cholesterol As Well As Some Fruits And Vegetables by American Chemical Society. (Science Daily)
(3) Dyslipidemia in Obesity: Mechanisms and Potential Targets by Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas. (PMC)
#Dry-Tomato-Peel (DTP) Reduces the Development of Indicators of MetabolicSyndrome, Particularly #InsulinResistance, Researchers Suggest
Kyle J. Norton
Insulin resistance is a condition in which cells that convert glucose to energy in the muscles, body fat, intestine, and liver ignore the signal o the hormone insulin signaling.
In other words, patients with insulin resistance are hyperglycemic. The syndrome is a hallmark of type 2 diabetes.
According to statistics, over 100 million Americans are living with insulin resistance. Approximately 1 in 3, including half of those age 60 and older have a silent blood sugar problem known as insulin resistance.
There are no single causes of insulin resistance, Epidemiologically, aging, ethnicity, overweight or obesity, too much belly fat, physical inactivity, smoking, and certain medical conditions such as Cushing’s disease or polycystic ovary disease is some of the prevalent factors that induce the risk of the condition.
However, most people with some of the aforementioned risk factors have never developed insulin resistance.
The most common symptoms of patients with insulin resistance are tiredness, hunger, and difficulty concentrating.
If you have experienced the above symptoms persistently, you may have insulin resistance, please make sure that you check with your doctor to rule out the possibility.
Out of many factors that increase the risk of insulin resistance, some researchers suggested the promotion of a high-fat diet over the past few decades may have a strong and negative impact on the rise of insulin resistance in the US.
Dr. Chad R. Hancock, the lead scientist wrote, "Feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria"
And, "a high-fat diet that raises FFA results in a gradual increase in mitochondria in rat skeletal muscle, with an increase in the capacity for fat oxidation, concomitant with the development of muscle insulin resistance".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
To find healthy food for controlling high blood glucose, researchers examined the effect of dry tomato peel (DTP) on insulin resistance, and atherogenic dyslipidemia induced by a high-saturated fat (HSF) diet in an animal model for 12 weeks.
The study included 40 selected BALB/c male mice (n=40) (8 weeks old, weighing 22.2±1.0 g) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the results from the tested assays, supplementation with DTP not only increased the plasma lycopene concentration and reduced the development of indicators of metabolic syndrome, particularly insulin resistance.
However, hepatic steatosis and inflammation caused by the injection of high-fat diet mice were not reversed with DTP supplementation.
In other words, DTP improved the plasma concentration of lycopene by normalizing the levels of blood glucose in tested mice through its anti-insulin resistance activity.
Dr. Zidani S, the lead scientist said, "Among mice fed the HSF/HC diet, DTP supplementation appears to have a beneficial effect on insulin resistance, which confirms the antiatherogenic effect of DTP".
In vivo, also in high-fat diet (HF)-induced obese mice, tomato vinegar beverage (TVB) at 14 mL kg(-1) body weight for 6 weeks not only inhibited the symptoms associated with fat accumulated in the liver but also promoted glucose tolerance, hyperinsulinemia, and HOMA-IR levels.
Levels of antioxidants in the tested were also significantly improved by TVB. TVB inhibited oxidative stress by significantly increasing glucokinase activity and decreased glucose-6-phosphatase activity in the liver,
More precisely, TVB enhanced glucose metabolism in obese mice. against the onset of insulin resistance.
Based on the findings, researchers wrote, "These results suggest that TVB prevents visceral obesity and insulin resistance via AMPK/PPARα-mediated fatty acid and glucose oxidation (Antioxidant property(TVB)".
Taken together, tomatoes may be considered a dietary supplement for the prevention and treatment of insulin resistance, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice by Seo KI1, Lee J, Choi RY, Lee HI, Lee JH, Jeong YK, Kim MJ, Lee MK. (PubMed)
(3) High-fat diets cause insulin resistance despite an increase in muscle mitochondria by Chad R. Hancock, Dong-Ho Han, May Chen, Shin Terada, Toshihiro Yasuda, David C. Wright, and John O. Holloszy. (PubMed)
Insulin resistance is a condition in which cells that convert glucose to energy in the muscles, body fat, intestine, and liver ignore the signal o the hormone insulin signaling.
In other words, patients with insulin resistance are hyperglycemic. The syndrome is a hallmark of type 2 diabetes.
According to statistics, over 100 million Americans are living with insulin resistance. Approximately 1 in 3, including half of those age 60 and older have a silent blood sugar problem known as insulin resistance.
There are no single causes of insulin resistance, Epidemiologically, aging, ethnicity, overweight or obesity, too much belly fat, physical inactivity, smoking, and certain medical conditions such as Cushing’s disease or polycystic ovary disease is some of the prevalent factors that induce the risk of the condition.
However, most people with some of the aforementioned risk factors have never developed insulin resistance.
The most common symptoms of patients with insulin resistance are tiredness, hunger, and difficulty concentrating.
If you have experienced the above symptoms persistently, you may have insulin resistance, please make sure that you check with your doctor to rule out the possibility.
Out of many factors that increase the risk of insulin resistance, some researchers suggested the promotion of a high-fat diet over the past few decades may have a strong and negative impact on the rise of insulin resistance in the US.
Dr. Chad R. Hancock, the lead scientist wrote, "Feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria"
And, "a high-fat diet that raises FFA results in a gradual increase in mitochondria in rat skeletal muscle, with an increase in the capacity for fat oxidation, concomitant with the development of muscle insulin resistance".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
To find healthy food for controlling high blood glucose, researchers examined the effect of dry tomato peel (DTP) on insulin resistance, and atherogenic dyslipidemia induced by a high-saturated fat (HSF) diet in an animal model for 12 weeks.
The study included 40 selected BALB/c male mice (n=40) (8 weeks old, weighing 22.2±1.0 g) divided into four treatment groups (10 mice/group): (a) high-fat control diet (HF Ctrl), which contains sunflower oil as a sole source of fat; (b) HSF/high-cholesterol (HC) diet; (c) HSF/HC diet supplemented with 9% DTP and (d) HSF/HC diet supplemented with 17% DTP.
According to the results from the tested assays, supplementation with DTP not only increased the plasma lycopene concentration and reduced the development of indicators of metabolic syndrome, particularly insulin resistance.
However, hepatic steatosis and inflammation caused by the injection of high-fat diet mice were not reversed with DTP supplementation.
In other words, DTP improved the plasma concentration of lycopene by normalizing the levels of blood glucose in tested mice through its anti-insulin resistance activity.
Dr. Zidani S, the lead scientist said, "Among mice fed the HSF/HC diet, DTP supplementation appears to have a beneficial effect on insulin resistance, which confirms the antiatherogenic effect of DTP".
In vivo, also in high-fat diet (HF)-induced obese mice, tomato vinegar beverage (TVB) at 14 mL kg(-1) body weight for 6 weeks not only inhibited the symptoms associated with fat accumulated in the liver but also promoted glucose tolerance, hyperinsulinemia, and HOMA-IR levels.
Levels of antioxidants in the tested were also significantly improved by TVB. TVB inhibited oxidative stress by significantly increasing glucokinase activity and decreased glucose-6-phosphatase activity in the liver,
More precisely, TVB enhanced glucose metabolism in obese mice. against the onset of insulin resistance.
Based on the findings, researchers wrote, "These results suggest that TVB prevents visceral obesity and insulin resistance via AMPK/PPARα-mediated fatty acid and glucose oxidation (Antioxidant property(TVB)".
Taken together, tomatoes may be considered a dietary supplement for the prevention and treatment of insulin resistance, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets by Zidani S1, Benakmoum A2, Ammouche A3, Benali Y4, Bouhadef A4, Abbeddou S. (PubMed)
(2) Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice by Seo KI1, Lee J, Choi RY, Lee HI, Lee JH, Jeong YK, Kim MJ, Lee MK. (PubMed)
(3) High-fat diets cause insulin resistance despite an increase in muscle mitochondria by Chad R. Hancock, Dong-Ho Han, May Chen, Shin Terada, Toshihiro Yasuda, David C. Wright, and John O. Holloszy. (PubMed)
#OleanolicAcid, Inhibits #Hyperglycemia that Causes #Diabetes and #CardiovascularDiseases in Vivo, According to Studies
Kyle J. Norton
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.
Traditional Chinese medicine views the pancreas as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our bodies.
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy). ...
Oleanolic acid is a phytochemical in the subclass of triterpenoid, belongings to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.
In finding a potential plant that processes anti-chronic disease activity researchers examined the hematological effects of oleanolic acid (OA) in streptozotocin- (STZ-) induced diabetic rats.
The study included animals that were separated into five groups; the non-diabetic group (ND), the diabetic control group (DC), and the treatment groups of insulin (170 μg/kg, s.c), metformin (500 mg/kg, p.o), and OA (80 mg/kg, p.o). OA was administered orally twice a day.
According to the results of the analysis,
* Untreated diabetic rats exhibited hyperglycemia, elevated glycated hemoglobin (HbA1c), oxidative stress, and a reduced erythropoietin (EPO) concentration when compared to ND rats.
* The administration of OA attenuated hyperglycemia, HbA1c, and EPO concentrations compared to DC rats.
* Furthermore, OA also decreased the blood glucose concentration, HbA1c, and improved EPO concentrations associated with a notable increase in red blood cell (RBC) count and other RBC indices.
* Moreover, OA increased the antioxidant status of the RBCs with a concomitant decrease in oxidative stress.
Collectively, researchers said, "These findings suggest that OA improves diabetes-induced hematological changes caused by hyperglycemia and attenuates the progression of cardiovascular complications in DM individuals".
Taken altogether, oleanolic acid may be considered a remedy for the prevention and treatment of diabetes, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers by Baloyi CM1, Khathi A1, Sibiya NH2, Ngubane PS. (PubMed)
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.
Traditional Chinese medicine views the pancreas as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our bodies.
According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.
About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.
Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.
Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.
Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy). ...
Oleanolic acid is a phytochemical in the subclass of triterpenoid, belongings to the group of Terpenes found abundantly in honey mesquite, garlic, java apple, clove, etc.
In finding a potential plant that processes anti-chronic disease activity researchers examined the hematological effects of oleanolic acid (OA) in streptozotocin- (STZ-) induced diabetic rats.
The study included animals that were separated into five groups; the non-diabetic group (ND), the diabetic control group (DC), and the treatment groups of insulin (170 μg/kg, s.c), metformin (500 mg/kg, p.o), and OA (80 mg/kg, p.o). OA was administered orally twice a day.
According to the results of the analysis,
* Untreated diabetic rats exhibited hyperglycemia, elevated glycated hemoglobin (HbA1c), oxidative stress, and a reduced erythropoietin (EPO) concentration when compared to ND rats.
* The administration of OA attenuated hyperglycemia, HbA1c, and EPO concentrations compared to DC rats.
* Furthermore, OA also decreased the blood glucose concentration, HbA1c, and improved EPO concentrations associated with a notable increase in red blood cell (RBC) count and other RBC indices.
* Moreover, OA increased the antioxidant status of the RBCs with a concomitant decrease in oxidative stress.
Collectively, researchers said, "These findings suggest that OA improves diabetes-induced hematological changes caused by hyperglycemia and attenuates the progression of cardiovascular complications in DM individuals".
Taken altogether, oleanolic acid may be considered a remedy for the prevention and treatment of diabetes, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers by Baloyi CM1, Khathi A1, Sibiya NH2, Ngubane PS. (PubMed)
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