#Avocado Inhibits #ProstateCancer by Stimulating the Production of #Protein Associated with Cell Cycle Progression and Cell Apoptosis, Researchers Say

Kyle J. Norton

Scientists may have found a popular fruit that has a profound and positive effect on the prevention and treatment of prostate cancer, some studies suggested.

Prostate cancer is a medical and chronic disease characterized by cells growing disorderly and uncontrollably in the tissue of prostate gland. At the later stage, cancerous cells may travel a distance away from the prostate gland to infect other healthy tissue and organs.


According to a statistic in the US, 1 in 9 men will be diagnosed with prostate cancer during their lifetime. Approximately, 6 cases out of 10 diagnosed with the condition are men aged 65 or older.

In 2017, 21,300 men in Canada were diagnosed with prostate cancer which represents 21% of all new cancer cases in men. And 4,100 men died from the disease(4).

Although Inherited mutations such as BRCA1 and BRCA2 that cause abnormal cell growth in the prostate gland are considered a major cause of prostate cancer, Acquired gene mutations such as overproduction of androgens (male hormones) gene that promotes prostate cell growth also contribute to prostate cancer risk in some men.

However, years of studies also suggested that increases in age, ethnic group, family history, obesity, environmental chemical,.... and unhealthy diet also have a strong implication in induction to the onset of prostate cancer.


Due to the slow progression of the disease, most patients do not experience any symptoms until the advanced stage. The most common symptoms include blood in the urine (hematuria), burning or pain during urination, difficulty urinating, decreased flow or velocity of urine stream, ......more frequent urges to urinate at night.

In some cases, patients may also be a loss of bladder control.

If you experience some of the above symptoms, please check with your doctor immediately to rule out the possibility.

Avocados are a commercially valuable fruit cultivated in tropical climates throughout the world.

The fruit has a green-skinned, pear-shaped fruit that ripens after harvesting, native to the Caribbean, Mexico, South America, and Central America, belonging to the flowering plant family Lauraceae.


Chemical constituents
The fruit contains campesterol, high amounts of β-sitosterol; fatty acids (approximately 60% monounsaturated, 20% saturated, and 20% unsaturated); high amounts of glutathione (27.7 mg/100 g); approximately 2% protein; 6–9% carbohydrates and sugars (glucose, fructose, d-mannoheptulose, a taloheptulose, and an alloheptulose); two bitter substances (1-acetoxy-2,4-dihydroxyheptadeca-16-ene and 1,2,4-trihydroxyheptadeca-16-ene); carnitine; proanthocyanidins; persenones A and B(a).

According to the Case-control study of 209 men 40-80 years old with newly diagnosed, histologically confirmed prostate cancer and 226 cancer-free men attending the same urology clinics conducted by the University of the West Indie, intake of dietary MUFA from whole fruit of avocado are associated to reduced risk and treatment of prostate cancer(1).

Dr. Jackson MD, the lead scientist said, "Whole-blood and dietary MUFA reduced the risk of prostate cancer. The association may be related to avocado intakes. High blood linolenic acid was directly related to prostate cancer" and " Dietary intakes of other fats were not associated with PCa"(1).

The University of California study showed that the anti-prostate cancer effects of avocado are not attributed to a single ingredient such as carotenoids (zeaxanthin, alpha-carotene, and beta-carotene), lutein but the interaction of all ingredients in the whole fruit in combination with other diet-derived phytochemicals(2).

The study suggested, intake of avocado stimulated the increased production of increase in p27 protein which involves function as tumor suppressor in controlling the cell cycle progression, in incubated PC-3 cells(2)

Avocado induced PC- 3 cancer cell death through cell apoptosis through G(2)/M cell cycle arrest the study continued(2).

In the evaluation of the effect of the anticancer of avocado conducted by the Purdue University study also showed a positive effect of the whole fruit in inhibition of six human tumor cell lines in culture, including human prostate adenocarcinoma (PC-3) cells(3).

The newly isolated Compounds 3 form of avocado containing g 1,2,4-triol moiety and a long aliphatic chain that terminates as either an alkane, alkene, or alkyne, respectively, exerted the strongest activity against PC-3 comparable to adriamycin, an anti-cancer conventional medicine(3).


Furthermore, when tested against yellow fever mosquito larvae, the 3-form avocado also was more effective than rotenone, a natural botanical insecticide(3).

Therefore, men who are at high risk of prostate cancer may want to add a portion of avocado into their daily diet for preventive measures.

Taken together, avocados with abundant carotenoids (zeaxanthin, alpha-carotene, and beta-carotene), and lutein may be considered a functional food for the prevention and treatment of prostate cancer.

However, additional large sample sizes and multicenter clinical trials with human consumption during the course of the disease are necessary to reconfirm avocado anti-prostate cancer possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(a) Leung's Encyclopedia of Natural Ingredients:Chemical Composition of Avocado
(1) Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica by Jackson MD1, Walker SP, Simpson-Smith CM, Lindsay CM, Smith G, McFarlane-Anderson N, Bennett FI, Coard KC, Aiken WD, Tulloch T, Paul TJ, Wan RL. (PubMed)
(2) Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances. by Lu QY1, Arteaga JR, Zhang Q, Huerta S, Go VL, Heber D.(PubMed)
(3) Cytotoxic and insecticidal constituents of the unripe fruit of Perseaamericana by Oberlies NH1, Rogers LL, Martin JM, McLaughlin JL.(PubMed)
(4) Prostate cancer statistics, Canadian Cancer Society
12. Avocado and Skin health
13. Avocado and Cadiovascular diseases

#Greentea's Polyphenols Inhibits All Parameters Associated with the Onset of #MetabolicSyndrome, Researchers Say

Kyle J. Norton


A recent study conducted by some renowned institutes suggested that regular drinking of green tea may inhibit the early onset of metabolic syndrome.

Metabolic syndrome is a cluster condition associated with an increased risk of heart disease, stroke, and diabetes, including abnormal high blood pressure, high blood sugar, and cholesterol together with excess body fat around the waist.

People with 3 of the above medical conditions are considered to have metabolic syndrome.

According to statistics, approximately, 25% of the US adult population has metabolic syndrome.

Some researchers suggested that the syndrome is also associated with the condition of obesity as they share a similar component of insulin resistance.

Truly, the syndrome is not caused by a single condition but is associated with a collection of risk factors,
including increases with age. race, obesity, diabetes, and other diseases (cardiovascular disease, nonalcoholic fatty liver disease, or polycystic ovary syndrome).

The joint study led by the University of South Florida Morsani College of Medicine investigated the prevalence of metabolic syndrome (MetS) and its components among U.S. adults, using the National Health and Nutrition Examination Survey 2007-2014 data suggested, ".... from 2007 to 2014, the prevalence of MetS remained stable in all sex, age, and race/ethnicity groups. Among the components of MetS, the prevalence of hypertriglyceridemia and fasting hyperglycemia decreased". and "The prevalence of elevated blood pressure and low high-density lipoprotein cholesterol level remained stable"(4).

Further analysis of the data, scientists found that the prevalence of abdominal obesity continues to increase in women, which can have a strong and lifelong impact on the induction of a higher risk of metabolic syndrome.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.

In a cross-sectional population-based survey including 8,821 adults (51.4% female) conducted in Krakow, Poland., both coffee and tea drinkers showed a negatively associated with MetS (OR 0.75, 95% CI 0.66, 0.86, and OR 0.79, 95% CI 0.67, 0.92, respectively).

The study also found that high tea consumers had lower BMI, and waist circumference, but moderated decreased diastolic blood pressure, as well as negatively correlated central obesity and fasting plasma glucose in women, but not in men, in compared low drinkers,


Furthermore, in the study including 8821 adults (51.4 % female), using food frequency questionnaires and matching food consumption data with the Phenol-Explorer database. conducted in Kraków, Poland, dietary polyphenol intake, a major compound found in green tea was associated inversely to the development of MetS (OR 0.80; 95 % CI 0.64, 0.98, and OR 0.70; 95 % CI 0.56, 0.86 for both men and women, respectively) in the highest quartile.

Dietary polyphenols in high quality also showed a negative association of WC, blood pressure, high lipoprotein cholesterol, and triglycerides in women, and fasting plasma glucose in both genders.

Dr. Grosso G, the lead author said, "(Depending on types of polyphenols) phenolic acids and stilbenes were significantly associated with MetS; lignans and stilbenes with WC; phenolic acids with blood pressure and triglycerides; and flavonoids with fasting plasma glucose" and " Among specific subclasses of polyphenols, hydroxycinnamic acids, flavonols, and dihydrochalcones had the most relevant role."

In support, of the role of a polyphenol for the treatment of Metabolic syndrome, a study of a total of 2725 participants free of hypertension at baseline tested for blood pressure or taking hypertensive medication within the last 2 weeks at 2-4-year follow-up visit was conducted by the Integrated Cancer Registry of Catania-Messina-Siracusa-Enna.

The final results showed that the diet of the highest quartile of total polyphenol intake was associated with a 31% decrease in the risk of hypertension compared with the lowest intake (OR 0.69, 95% CI 0.48, 0.98) in women with no significant association in men.

The study also stated that the most influential phytochemicals in reduced risk and treatment of metabolic syndrome ingredients are phenolic acids, hydroxycinnamic acids as they showed an independently associated with lower odds of hypertension (OR 0.66, 95% CI 0.47, 0.93) in comparison to others.

Taking together, green tea with major chemical compounds of polyphenol may be used as a functional food in inhibiting a cluster of conditions associated with the onset of metabolic syndrome.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years


Sources
(1) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3. (PubMed)
(2) Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Stefler D4, Bobak M4, Pająk A3. (PubMed)
(3) Dietary polyphenol intake and risk of hypertension in the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Kozela M3, Stefler D4, Bobak M4, Pajak A3. (PubMed)
(4) Trends in the prevalence of metabolic syndrome and its components in the United States 2007-2014 by Shin D1, Kongpakpaisarn K2, Bohra C(PubMed)

#Yoga Intervention May be Useful for Reducing Pain in Patients with #RheumaticDiseases by increasing the Release of Natural Pain-Relieving Chemicals Endorphins, Researchers Suggest

Kyle J. Norton

Yoga intervention may have a profound effect to alleviate pain and treat rheumatic diseases, some studies suggested.

Rheumatic diseases are a condition of Musculoskeletal disorders, affecting the joints and muscles.

Yoga, the accident technique practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts of Asia.

In a study to compare the effect of Tai Chi and yoga therapies in treatments for rheumatologic and musculoskeletal diseases, researchers filed the following report
* Both therapy displays a significant effect of Tai Chi and yoga in the management of rheumatologic diseases, particularly in osteoarthritis of the knee, hip, and hand, and rheumatoid arthritis pain.

* Tai Chi and yoga are safe, expressed a reduction of pain, and improvement of physical function and quality of life in patients with rheumatic diseases.

By the information collected, Uhlig T, the led author said, "Recommendations for Tai Chi in knee osteoarthritis have recently been issued by the American College of Rheumatology. To allow broader recommendations for the use of Tai Chi and yoga in rheumatic diseases".

The study from McGill University, Montreal suggested that yoga lessons not only improve stress and anxiety and promote a sense of calmness, general well-being, and quality of life but also reduced inflammatory mediators including C-reactive protein and interleukin-6 in overexpression pain in participants with rheumatic disease.

Truly, regular yoga practice can increase muscle strength and endurance, proprioception, the sense equilibrium, and balance, depending on the notion of force and balance, with emphasis on movement through a full range of motion to increase flexibility and mobility, thus reducing physical symptoms in patients with rheumatic diseases.

Some researchers suggested that regular yoga practice
* can improve stress management and can have a feedback effect on improving chronic pain, by affecting the response to pain, and decreasing the level of perceived suffering.

* can improve the movement of joints, as motion and muscle stretching can decrease the intensity of pain or relieve your pain completely in some patients.

Furthermore, yoga breathing, and medication also were found to reduce chronic pain by calming the nervous system to block responses to pain messages, reducing inflammatory chemicals from communicating with nerves, and increasing the release of natural pain-relieving chemicals called endorphins.

However, in the review of randomized controlled trials (RCTs) by comparing yoga with control interventions in patients with rheumatic diseases by searching databases of Medline/PubMed, Scopus, the Cochrane Library, and IndMED through February 2013, eight RCTs selected met the guideline with a total of 559 subjects with two RCTs with a low risk of bias, researchers found that all studies expressed very low evidence for effects on pain and disability, in patients with rheumatic diseases participated in yoga classes, long and short terms.

Taken together, yoga practice may have a profound effect to alleviate pain and treat rheumatic diseases, however, larger randomized controlled trials. are necessary to reaffirm these possibilities


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Yoga for rheumatic diseases: a systematic review by Cramer H1, Lauche R, Langhorst J, Dobos G.(PubMed)
(2) Yoga in rheumatic diseases by Bartlett SJ1, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd.(PubMed)
(3) Tai Chi and yoga as complementary therapies in rheumatologic conditions by Uhlig T1.(PubMed)

Posted by Cha

#Polyphenon E Found in #Greent's Catechin Extract and Greentea's #EGCG Inhibit the Onset of #UlcerativeColitis through Inhibited Production of Inflammatory Factors, Researchers Find

Kyle J. Norton

Green tea may have a therapeutic and positive effect on the prevention and treatment of Ulcerative Colitis, some scientists suggested.

Ulcerative Colitis is a digestive condition characterized by inflammatory bowel disease (IBD) that induces chronic inflammation and ulcers (sores) in the digestive tract.

According to statistics, approximately, 250,000 and 500,000 people are infected by ulcerative colitis in the United States. The risk of ulcerative colitis onset is between 2 to 7 per 100,000 persons.

The most common symptoms are abdominal pain and diarrhea. However, some patients may also experience symptoms of fatigue or tiredness, loss of appetite, dehydration feeling the urge to empty the bowels constantly,.... and weight loss.

If you have some of the symptoms above, please check with your doctor to rule out the possibility of ulcerative colitis.

Researchers do not know the exact cause of Ulcerative Colitis.

Neither do they know why ulcerative colitis induces chronic inflammation and ulcers (sores) in the digestive tract.

However, they do know that certain risk factors are associated with the development of the disease, including genetic mutation of a certain gene, environmental toxins, overreaction of the immune system,.... and long-term high levels of linoleic acid intake.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.

As yin in nature, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

In mild to moderate ulcerative colitis (UC) patients, 15 received 400 mg or 800 mg of total Polyphenon E daily, administered in split doses or 4 in placebo in a double-blinded, placebo-controlled pilot study, researchers at the end of the experiential indicated that oral administration of the extracts exerts a potential effect of reduced levels of inflammation through the improvement of the reading of the mean UC disease activity index score compared to the entry score.

After 56 days of therapy, Polyphenon E treatment group exhibited strong improvement of over response rate of 66.7% (10 of 15) and remission rate of 53.3% (8/15) compared to 0% (0/4) in both response rate and remission rate in the placebo group.

Dr. Dryden GW, the lead author, after taking into account of other co-founder said, "Administration of Polyphenon E resulted in a therapeutic benefit for(ulcerative colitis (UC)) patients who were refractory to 5-aminosalicylic and/or azathioprine".

Polyphenon E is high-quality tea catechin extracted from natural tea leaves.

Further analysis of green tea bioactive polyphenols, epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway, indicated that application of the extract significantly improves the intestinal mucosal injury in rats through inhibited production of inflammatory factors which were overexpression during the acute phase of injuring and damage to induced further damage to the tissue.

Moreover, green tea bioactive polyphenols, epigallocatechin gallate (EGCG) also reduced chronic inflammation and maintained the balance of the ratio of Th1/Th2 T-helper (Th) lymphocytes that prevent alterations in cellular immunity in patients with ulcerative colitis.

Imbalance of Th1/Th2 was found to associate to the occurrence and development of ulcerative colitis.

Additionally, the injection of green tea EGCG also reduced the levels of TLR4 signaling in activated the intracellular signaling pathway NF-κB and inflammatory cytokine production to imitate inflammation.

Amazingly, researchers also found that injection of TLR4 antagonism not only shows a significantly reduced protective effect of EGCG on intestinal mucosal injury colitis but also increased the expressions of inflammatory factors in the production of pro-inflammatory cytokines.

Moreover, in the examine the antioxidant activity of green tea catechins in a model of colitis induced by 2.4.6 trinitrobenzene sulfonic acid (TNBS) using 35 young adult Sprague-Dawley rats which are divided into four groups: normal control (n=5), catechins (n=9), TNBS (n=9) and 2.4.6 trinitrobenzene sulfonic acid (TNBS) plus catechins (n=12), at the end of the experiment researchers at the Joint study, American University of Beirut, found that groups with TNBS and catechin express strong anti-inflammatory and anti-oxidant effects of amelioration of symptoms and expression of ulcerative colitis through stabilizing the mast cells production, induced by injection of TNBS in compared to TNBS treated group.

Dr. the lead authors in the joint study suggested that the study depicted a significant amelioration in the TNBS- and EGCG-treated rats compared to the non-treated animals in similar to histological data, as the mechanism of action occurred basically through the NF-kB pathway and possibly through crosstalk with other pathways.

Taken together, green tea and its bioactive polyphenols may be considered as functional foods for the prevention and treatment of ulcerative colitis through the expression of antioxidant and anti-inflammatory activity.

Intake of green tea extract should be taken with extreme care as acute toxicity has been reported in some cases.

https://kylejnorton.blogspot.com/2018/09/green-tea-beverage-which-blocks-onset.html

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299



Sources
(1) A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenol E in patients with mild to moderate ulcerative colitis by Dryden GW1, Lam A, Beatty K, Qazzaz HH, McClain CJ. (PubMed)
(2) Tea catechins induce crosstalk between signaling pathways and stabilize mast cells in ulcerative colitis by Gerges Geagea A1,2, Rizzo M2, Eid A1, Hajj Hussein I3, Zgheib Z1, Zeenny MN1, Jurjus R4, Uzzo ML5, Spatola GF5, Bonaventura G5, Leone A5, Massaad-Massade L6,7,8, Jurjus A1.(PubMed)
(3) EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats by TNBS,1 Liu Xuelei,2 Dong Wanwei,3 Liang Linlang,1 and Chen Keyan3(Hindawi)

#DriedPea #SolubleFiber Improves Postprandially in the Glycemic, Insulinemic, and FFA Responses In Type 2 Diabetes, Scientists Find

Kyle J. Norton

Scientists may have found a whole food with a potential effect on the management of type 2 diabetes, some studies suggested.

Type 2 Diabetes is a chronic medical condition characterized by insufficient insulin entering the bloodstream to neutralize the levels of glucose.

Type 2 Diabetes is caused either by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

In some cases, diabetes can also be caused by allergic reactions of cells in the immune system.

The exact causes of type 2 diabetes are unknown as researchers do not know why? people with same
health condition, some are susceptible to early onset of type 2 diabetes, while others do not.

However, some researchers suggested there are some major risk factors such as genetics and lifestyle associated with the early onset of insulin resistance.

Epidemiological studies also suggested that conditions such as being overweight, obesity, physical inactivity, family history, race, age, and high blood pressure are some prevalent risk factors for type 2 diabetes, especially, in women with polycystic ovary syndrome and previous gestational diabetes.

According to the World Health Organization, the number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014.

The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014.

Diabetes prevalence has been rising more rapidly in middle- and low-income countries.

Sadly, untreated or improperly managed diabetes are leading cause of kidney failure, lower-limb amputations, and adult-onset blindness.

Dried peas are a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae.

Fried peas are also healthy sources of protein, fiber, vitamins, and minerals that are good for everyone's diet.

To understand more of a low-glycemic response versus a high-glycemic response breakfast meal on postprandial serum glucose, insulin, and free fatty acid (FFA) responses after consumption of a standardized mid-day meal in adult individuals with Type 2 diabetes mellitus (DM), researchers launched a randomized crossover intervention using control and test meals was conducted over a 3-week-period following an overnight fast of 8-10 h.

Patients included in the study were given either Breakfast (A), a high glycemic load breakfast meal consisting of farina (kJ 1833; carbohydrate (CHO) 78 g and psyllium soluble fiber 0 g), or breakfast (B) a low-glycemic load breakfast meal consists of a fiber-loop cereal (kJ 1515; CHO 62 g and psyllium soluble fiber 6.6 g) randomly.

Forty-five Type 2 DM subjects included in the study have completed the requirements. By observation of post-breakfast analyses experiment, researchers found that

* Breakfast B had significantly lower area under the curve (AUC) values for plasma glucose and insulin compared to Breakfast A (P<0.05).

* Post-lunch analyses indicated similar glucose responses for the two breakfast types.

* Insulin AUC values for Breakfast B were significantly lower than Breakfast A (P<0.05) (95% confidence level).

These result suggested that psyllium soluble fiber have a strong effect to reduce fasting glucose compared to a meal without. However, intake of psyllium soluble fiber showed insignificant improvement postprandially in the glycemic, insulinemic, and FFA responses after the consumption of the lunch meal.

Dr. Clark CA, the lead researcher also indicated, "These data revealed no residual postprandial effect of the psyllium soluble fiber breakfast meal beyond the second meal consumed".

Additionally, in a study to evaluate the glycemic and insulinemic effects of dried peas compared to potatoes researchers at the University of Göttingen conducted a study, using 3 different meals based on dried peas, potatoes, or both in patients with type 2 diabetes undergoing dietary treatment.

The tested meals were prepared according to local recipes and consumed at weekly intervals in random order at lunchtime, containing comparable amounts of carbohydrates, fat, protein, and water. The carbohydrate source of the meals differed and was supplied from either dried peas (meal 1), potatoes (meal 3), or a combination thereof (meal 2). Peripheral and venous blood was sampled over 180 min.

In the final report, researchers wrote,
* The increases in postprandial plasma glucose and insulin concentrations were delayed and significantly smaller after the peameal than after the potato meal.

* The areas under the glucose curve were 164, 257, and 381 mmol x 180 min/L for meals 1, 2, and 3, respectively (P < 0.01).

* The areas under the insulin curve were 13.8, 15.4, and 31.2 nmol x 180 min/L, respectively.

These results further reaffirm the effect of dried peas in delay and lower postprandial plasma glucose and insulin concentrations compared to potatoes.

Interestingly, researchers also strongly suggested, "..... carbohydrates in dried peas may be largely disregarded in carbohydrate counting and that type 2 diabetic patients should probably increase their consumption of low-glycemic, high-fiber foods at the expense of high-glycemic, low-fiber foods".


Taken together, dried peas may be considered a functional food for diabetes management by reducing postprandial plasma glucose and insulin concentrations in patients with type 2 diabetes.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299

References
(1) Effects of breakfast meal composition on second meal metabolic responses in adults with Type 2 diabetes mellitus by Clark CA, Gardiner J, McBurney MI, Anderson S, Weatherspoon LJ, Henry DN, Hord NG. (PubMed)
(2) Comparison of the effects of dried peas with those of potatoes in mixed meals on postprandial glucose and insulin concentrations in patients with type 2 diabetes by Schäfer G, Schenk U, Ritzel U, Ramadori G, Leonhardt U.(PubMed)

#Long Term #YogaExercises May Be Useful For the Improvement of#CognitiveFunction of Patients with #Schizophrenia, According to Studies

Kyle J. Norton

Epidemiological studies do agree that yoga lessons may reduce symptoms and complications expression in patients with Schizophrenia, a renowned university study suggested.

Schizophrenia is a mental disorder induced by inconsistent or contradictory elements such as the breakdown of certain relations in thought, emotion, and behavior, leading to faulty perception, inappropriate actions,.... and feelings.

The exact causes of schizophrenia are unknown. However, the National Health Service suggested that certain risk factors involving physical, genetic, psychological, and environmental circumstances are associated with the likeliness of a person to develop the condition.

Sadly, researchers do not know, why people with the same health condition, are susceptible to Schizophrenia development the while others do not.

Furthermore, stressful or emotional life events might trigger a psychotic episode in patients with Schizophrenia.

Yoga, the accident technique practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the clinically stable, adult outpatients with SZ (n=286) completed baseline assessments randomized to treatment as usual (TAU), supervised yoga training with TAU (YT) or supervised physical exercise training with TAU (PE) researchers at the joint study led by the University of Pittsburgh filed the following results
* After six months and follow-up, yoga showed a significant improvement in the speed index of the attention domain compared to control groups.

* In cognitive domains, yoga group demonstrated a significant improvement compared to PE and with TAU alone, respectively

The further assessment also suggested that both YT and PE improved attention and additional cognitive domains well past the training period, but only the YT group showed a beneficial effect on the speed index of the attention domain.

These results of improvement may be attributed to the repeated practice of attentional focus and redirecting attention may be a possible active ingredient for developing greater attentional control

Moreover, the physical and cognitive benefits associated with yoga and mindfulness may be due to mechanisms that activated the parasympathetic nervous system through meditative or contemplative practices.

Some researchers also suggested long-term yoga practice increases body perception, stronger functional connectivity within the basal ganglia, and increased activation of grey matter volume and amygdala with regional enlargement.

Additionally, in the review literature published in the databases of MEDLINE, PubMed, Embase, CINAHL, BIOS, AMED, and PsychINFO involved randomized controlled trials (RCTs) including people with schizophrenia comparing yoga as a package of care with standard-care control, researchers found only 3 studies with all outcomes were short-term (less than eight weeks) with none of them displayed a significant change of yoga group in compared to control.

The findings indicated that short-term yoga practice may have little effect on the improvement of cognitive function.

More importantly, from a patient perspective, in a study of a total of 100 schizophrenia patients (male: female = 57:43; age: 35.8 ± 9.2 years) attending the psychiatry out-patient services of a tertiary neuropsychiatry hospital administered a survey questionnaire, researchers at the National Institute of Mental Health and Neuro Sciences reported the following results
* 46% of a participant was aware that yoga is also one of the complementary therapies useful in schizophrenia.

* 32% had tried yoga in the past for some reason, but only 31% of them were continuing yoga with reasons of lack of motivation (31%) and inability to spare time (27.6%).

* However, the majority (88.5%) of them were willing to take up add-on yoga therapy on an outpatient basis along with their regular medical follow-up.

Taken together, long-term yoga lessons may be used as a secondary and therapeutic enhancement of cognitive function in patients with schizophrenia.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Yoga as part of a package of care versus standard care for schizophrenia by Broderick J1, Vancampfort D.(PubMed)
(2) A randomized controlled trial of adjunctive yoga and adjunctive physical exercise training for cognitive dysfunction in schizophrenia by Bhatia T1, Mazumdar S2, Wood J3, He F2, Gur RE4, Gur RC4, Nimgaonkar VL5, Deshpande SN6.(PubMed)
(3) Yoga for schizophrenia: Patients' perspective by Govindaraj R1, Varambally S1, Gangadhar BN1.(PubMed)
(4) Effects of weekly one-hour Hatha yoga therapy on resilience and stress levels in patients with schizophrenia-spectrum disorders: an eight-week randomized controlled trial by Ikai S1, Suzuki T, Uchida H, Saruta J, Tsukinoki K, Fujii Y, Mimura M.(PubMed)
(5) A yoga program for cognitive enhancement by (PMC)

#Glycoalkaloids Derived from Eggplant Exert A Strong #Anti-#Cancer Activity, Scientists show

Kyle J. Norton

Eggplant, the nightshade vegetable may be considered a functional food for the prevention and treatment of cancers, some researchers suggested.
Cancers are a class of chronic diseases caused alternation of DNA of healthy cells.

In other words, healthy cells become cancerous if they grow uncontrollably and disorderly out of range of a normal healthy cell population which can only divide between 40 and 60 times.

According to the Hayflick limit theory, most cells' survival is totally dependent on the telomeres on the ends of each chromosome.

Every time, healthy cells undergo division, the telomeres are shortened. Once the telomeres shorten to a critical length, the cells will die off.

In the advanced stage, traveling through fluid and blood circulation, most invasive cancer cells can infect healthy cells or tissue a distance away from the originated site.

According to the statistic provided by the Canadian Health Service, In 2017, over 200,000 Canadians will be diagnosed with cancer, and 80,000 will die from cancer.

Sadly, 1 in 2 Canadians will be diagnosed with cancer during their lifetime and 1 in 4 will die from the disease.

Lung, colorectal, breast, and prostate cancers are the most common cancer found in Canadian, accounting for half of all cancers diagnosed.

And 60% of Canadians diagnosed with cancer will survive at least 5 years after their diagnosis.

Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.

The plant has been cultivated in southern and eastern Asia since prehistory.

Eggplant is famous for its deep purple and the best eggplant can be found from August through October when it is in season.


In an effort to find plant-derived foods such as potatoes, eggplants, and tomatoes with potential antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells, researchers at Yeungnam University conducted a study to evaluate a series of structurally related individual compounds in these plants, using microculture tetrazolium (MTT) assay.
Glycoalkaloids solamargine and solasonine and their common aglycon solasodine; and the nonsteroidal alkaloid jervine isolated from eggplant were selected to test the possibilities of the anti-cancer compared to other compounds isolated from potatoes and tomatoes.

After taking into account other factors, researchers found that
* Glycoalkaloids derived from eggplant exert the most active anticancer cells compared to others. However, its hydrolysis products are less active compared to glycoalkaloids.

* Compounds isolated from eggplant are very effective against liver cancer cells compared to colon cancer cells.

Dr. Lee KR, the lead author on the final report said, "....safety considerations should guide the use of these compounds preventative or therapeutic treatments against carcinomas".

Furthermore, in the study to investigate the inhibitory effect of eggplant (Solanum melongena var. marunasu) extract on the human fibrosarcoma HT-1080 cell invasion of reconstituted basement membrane [Matrigel (MG)], researchers discovered

* Delphinidin, a flavonoid pigment contained in the peel demonstrates the most effective against human fibrosarcoma HT-1080 cells.

* Interestingly, the application of eggplant extract and delphinidin did not affect tumor cell adhesion to MG or haptotaxis migration to MG.

Further analysis of these effects, researchers found that the inhibition of cancer was attributed to
delphinidin of blocking the activity of Matrix metalloproteinases MMPs which are responsible for the degradation of most extracellular matrix proteins during organogenesis, growth, and normal tissue turnover.

The findings suggested that the frequency of eggplant intake may associate to reduce the risk of cancers. However, further data collection on large example size and multi-center studies performed with human consumption of whole food eggplant during the course of cancer will be necessary to complete the picture of eggplant and its bioactive ingredients anti-cancer possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M.(PubMed)
(2) Inhibitory effect of delphinidin from Solanum melongena on human fibrosarcoma HT-1080 invasiveness in vitro by Nagase H1, Sasaki K, Kito H, Haga A, Sato T.(PubMed)